1. A composition comprising a genogroup I Norovirus virus-like particle (VLP) and a genogroup II Norovirus VLP, wherein the
genogroup I and genogroup II Norovirus VLPs are present in the composition in different amounts, and wherein the genogroup
I Norovirus VLP is present in the composition at an amount of about 15 ?g and the genogroup II Norovirus VLP is present in
the composition at an amount of about 50 ?g.