US Patent No. 9,790,199

SULFOXIDE COMPOUND AND METHOD OF PRODUCING BENZOTHIOPHENE DERIVATIVES USING THE SAME


Patent No. 9,790,199
Issue Date October 17, 2017
Title Sulfoxide Compound And Method Of Producing Benzothiophene Derivatives Using The Same
Inventorship Ming-Jung Wu, Kaohsiung (TW)
Shih-Ming Wen, Kaohsiung (TW)
Assignee NATIONAL SUN YAT-SEN UNIVERSITY, Kaohsiung (TW)

Claim of US Patent No. 9,790,199

1. A method of producing benzothiophene derivatives, comprising:
performing a reaction between a sulfoxide compound of formula (I) and an alkynyl compound of formula (II) to produce the benzothiophene
derivatives of formula (III):


wherein R1 and R2 are individually and independently benzoyl group; alkyl, acyl or silyl group of C1-C6 straight chain or branched chain; or alkenyl group of C3-C6 straight chain or branched chain; and X is halogen atom;


wherein in the formula (II), A is hydrogen atom or silyl group, and R4 is benzoyl group; alkyl, acyl or silyl group of C1-C6 straight chain or branched chain; or alkenyl group of C3-C6 straight chain or branched chain; and


wherein in the formula (III), R1 and R2 are individually and independently hydrogen atom, benzoyl group; alkyl, acyl, or silyl group of C1-C6 straight chain or branched chain; or alkenyl group of C3-C6 straight chain or branched chain, and R3 is hydrogen atom or (1-piperidinyl)-(C1-C4)alkyl group.