1. A therapeutic nanoparticle comprising:
about 4 to about 25 weight percent of a therapeutic agent;
about 10 to about 99 weight percent of a diblock poly(lactic) acid-poly(ethylene)glycol copolymer comprising poly(lactic)
acid having a number average molecular weight of about 15 to 20 kDa, and poly(ethylene)glycol having a number average molecular
weight of about 4 to 6 kDa;
wherein the hydrodynamic diameter of the therapeutic nanoparticle is about 60 nm to about 140 nm; and
wherein the therapeutic nanoparticles releases less than 2% of the therapeutic agent over about one minute when placed in
a phosphate buffer solution at 37Â° C.