US Patent No. 9,550,795

HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE COMPOUNDS


Patent No. 9,550,795
Issue Date January 24, 2017
Title Hexahydropyrano[3,4-d][1,3]thiazin-2-amine Compounds
Inventorship Michael Aaron Brodney, Newton, MA (US)
Christopher Ryan Butler, Canton, MA (US)
Christopher John Helal, Mystic, CT (US)
Assignee Pfizer Inc., New York, NY (US)

Claim of US Patent No. 9,550,795

1. A compound selected from the group consisting of
(4aR,6R,8aS)-8a-(2-Fluorophenyl)-6-[(pyridin-2-yloxy)methyl]-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine;
(4aR,6R,8aS)-8a-(2-Fluorophenyl)-6-[(pyrazin-2-yloxy)methyl]-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine; and
(4aR,6R,8aS)-8a-(2-Fluorophenyl)-6-[(pyrimidin-2-yloxy)methyl]-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine;
or a pharmaceutically acceptable salt thereof.