1. A lyophilized pharmaceutical composition comprising: polymeric nanoparticles comprising: a poly(lactic) acid-block-poly(ethylene)glycol
copolymer or poly(lactic)-co-poly(glycolic) acid-block-poly(ethylene)glycol copolymer, and a therapeutic agent;
a sugar; and
wherein upon reconstitution of the lyophilized pharmaceutical composition in an aqueous medium, the composition comprises
4 to 6 weight percent of the sugar; and 7 to 12 weight percent of the hydroxypropyl ?-cyclodextrin.