US Patent No. 9,409,962

METHODS AND COMPOSITIONS FOR EXPRESSING FUNCTIONAL CLASS XIV MYOSIN


Patent No. 9,409,962
Issue Date August 09, 2016
Title Methods And Compositions For Expressing Functional Class Xiv Myosin
Inventorship Kathleen M. Trybus, Burlington, VT (US)
Gary E. Ward, Burlington, VT (US)
Assignee University of Vermont and State Agricultural College, Burlington, VT (US)

Claim of US Patent No. 9,409,962

1. A method of producing a functional class XIV myosin polypeptide, the method comprising,
co-expressing three or more polynucleotides in a heterologous expression-system cell, wherein the three or more polynucleotides
comprise a class XIV heavy chain polypeptide-encoding polynucleotide, a first myosin light chain polypeptide-encoding polynucleotide,
and a parasite co-chaperone polypeptide-encoding polynucleotide, wherein the three or more polynucleotides are co-expressed
in the cell under conditions suitable to produce a functional class XIV myosin polypeptide comprising the class XIV heavy
chain polypeptide and the first myosin light chain polypeptide.