US Patent No. 9,308,249
NOROVIRUS VACCINE FORMULATIONS
| Patent No. | 9,308,249 |
|---|---|
| Issue Date | April 12, 2016 |
| Title | Norovirus Vaccine Formulations |
| Inventorship | Charles Richardson, Bozeman, MT (US) Thomas S. Vedvick, Federal Way, WA (US) Thomas R. Foubert, Bozeman, MT (US) William T. Tino, Belgrade, MT (US) |
| Assignee | TAKEDA VACCINES, INC., Bozeman, MT (US) |
Claim of US Patent No. 9,308,249
1. An immunogenic composition comprising at least one Norovirus antigen and an effective amount of at least one adjuvant,
wherein the adjuvant is a toll-like receptor (TLR) agonist that is not a bacterial exotoxin, wherein said antigen comprises
Norovirus virus-like particles (VLPs), and wherein the composition is formulated as a stable dry powder, wherein the percent
aggregation of VLPs in the composition remains constant or decreases when measured over a twelve month period.
wherein the adjuvant is a toll-like receptor (TLR) agonist that is not a bacterial exotoxin, wherein said antigen comprises
Norovirus virus-like particles (VLPs), and wherein the composition is formulated as a stable dry powder, wherein the percent
aggregation of VLPs in the composition remains constant or decreases when measured over a twelve month period.