1. An immunogenic composition comprising at least one Norovirus antigen and an effective amount of at least one adjuvant,
wherein the adjuvant is a toll-like receptor (TLR) agonist that is not a bacterial exotoxin, wherein said antigen comprises
Norovirus virus-like particles (VLPs), and wherein the composition is formulated as a stable dry powder, wherein the percent
aggregation of VLPs in the composition remains constant or decreases when measured over a twelve month period.