US Patent No. 9,129,790

ORTHOGONAL ACCELERATION TOF WITH ION GUIDE MODE


Patent No. 9,129,790
Issue Date September 08, 2015
Title Orthogonal Acceleration Tof With Ion Guide Mode
Inventorship David G. Welkie, Trumbull, CT (US)
Assignee PerkinElmer Health Sciences, Inc., Waltham, MA (US)

Claim of US Patent No. 9,129,790

1. A system, comprising:
an electronic controller; and
a time-of-flight mass analyzer in communication with the electronic controller, the time-of-flight mass analyzer comprising:
a pulsing region defining a channel that extends along an axis, the pulsing region comprising:
a first electrode extending along the axis, the first electrode defining one or more apertures;
a second electrode extending along the axis, the first and second electrodes being positioned on opposing sides of the axis
in a first direction perpendicular to the axis;

a third electrode extending along the axis; and
a fourth electrode extending along the axis, the third and fourth electrodes being positioned on opposing sides of a plane
defined by the axis and the first direction,

wherein:
the electronic controller is programmed to apply a first set of voltages to the electrodes to constrain a motion of ions propagating
along the axis in a radial direction relative to the axis, and apply a second set of voltages to the electrodes to accelerate
the ions out of the pulsing region through the one or more apertures, where the first set of voltages comprises RF voltages
applied to the first and second electrodes, the RF voltages being in phase with each other.