US Patent No. 9,107,923

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS


Patent No. 9,107,923
Issue Date August 18, 2015
Title Heteroaromatic Compounds And Their Use As Dopamine D1 Ligands
Inventorship Michael Aaron Brodney, Newton, MA (US)
Jennifer Elizabeth Davoren, Cambridge, MA (US)
Amy Beth Dounay, Colorado Springs, CO (US)
Ivan Viktorovich Efremov, Brookline, MA (US)
David Lawrence Firman Gray, Groton, MA (US)
Michael Eric Green, Boston, MA (US)
Jaclyn Louise Henderson, Cambridge, MA (US)
Chewah Lee, Wallingford, CT (US)
Scot Richard Mente, Arlington, MA (US)
Bruce Nelsen Rogers, Belmont, MA (US)
Lei Zhang, Auburndale, MA (US)
Assignee Pfizer Inc., New York, NY (US)

Claim of US Patent No. 9,107,923

1. A compound selected from the group consisting of:
6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione;
1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)pyrimidine-2,4(1H,3H)-dione; and
6-{4-[(3-chloropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione,or a pharmaceutically acceptable salt thereof.