US Patent No. 11,110,105

COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER


Patent No. 11,110,105
Issue Date September 07, 2021
Title Compounds, Composition And Uses Thereof For Treating Cancer
Inventorship Alison Pierson, Villejuif (FR)
Mathilde Boulpicante, Chevilly-Larue (FR)
Zafiarisoa Dolor Renko, Les Ulis (FR)
Mouad Alami, Bussy Saint Georges (FR)
Romain Darrigrand, Ivry sur Seine (FR)
Assignee INSTITUT GUSTAVE ROUSSY, Villejuif (FR)

Claim of US Patent No. 11,110,105


1. A medicament comprising a compound of formula



wherein R1 and R2 are independently selected from the group consisting of Na, H, —CH3, —CH2—CH3, —CH2—CH?CH3, n-CH2—CH2—CH3, P(O)(O—CH2—CH3)2, P(O)(OH)2 or P(O)(ONa)2 and wherein R1, R2, R3, R4 and R5 are not H simultaneously, wherein R1 is not —CH3 when R2 is P(O)(ONa)2 or P(O)(OH)2 and each of R3, R4 and R5 is H, and wherein R1 is not —CH3 or H when R2 is —CH3 and each of R3, R4 and R5 is H; and
wherein R3, R4 and R5 are independently selected from the group consisting of H, CH3, —CH2—CH3, —CH2—CH?CH3, and CnH2n+1 with n=3?10.