US Patent No. 11,110,092

METHODS OF TREATING HEMATOLOGIC CANCERS


Patent No. 11,110,092
Issue Date September 07, 2021
Title Methods Of Treating Hematologic Cancers
Inventorship Shanta Bantia, Birmingham, AL (US)
Philip Breitfeld, Birmingham, AL (US)
Yarlagadda S Babu, Birmingham, AL (US)
Assignee BIOCRYST PHARMACEUTICALS, INC., Durham, NC (US)

Claim of US Patent No. 11,110,092


1. A method of treating a hematologic cancer in a subject comprising the steps of:a. administering to the subject an effective amount Forodesine; and
b. administering to the subject an effective amount of an alkylating agent, wherein the administration of Forodesine and the alkylating agent results in a synergistic effect, wherein the alkylating agent is Bendamustine and the hematologic cancer is resistant to Bendamustine and Fludarabine.