US Patent No. 10,987,039

MICRONEEDLE ARRAY DEVICE AND METHOD OF MAKING


Patent No. 10,987,039
Issue Date April 27, 2021
Title Microneedle Array Device And Method Of Making
Inventorship Vincenza Di Palma, Cimitile (IT)
Maria Fortuna Bevilacqua, Gragnano (IT)
Andrea Di Matteo, Naples (IT)
Principia Dardano, Ercolano (IT)
Assignee STMICROELECTRONICS S.R.L., Agrate Brianza (IT)

Claim of US Patent No. 10,987,039

1. A microneedle array device comprising:a substrate;
an array of microneedles on the substrate, wherein each microneedle is made of a hydrogel, the hydrogel comprising a redox enzyme and a redox mediator; and
an electrically conductive layer on the substrate, wherein the electrically conductive layer extends along a sidewall of each microneedle of the array of microneedles to a first height without covering a tip of a corresponding microneedle, the first height being between about 30% to about 90% of a height of the corresponding microneedle, wherein the electrically conductive layer does not extend into the corresponding microneedle, wherein the electrically conductive layer does not extend directly under the corresponding microneedle, and wherein the tip of the corresponding microneedle not covered with the electrically conductive layer is configured to act as a sensing area of the microneedle array device and to shuttle electrons from the redox mediator through the hydrogel to the electrically conductive layer.