US Patent No. 10,835,597

COMPOSITIONS AND METHODS FOR STABILIZING FLAVIVIRUSES WITH IMPROVED FORMULATIONS


Patent No. 10,835,597
Issue Date November 17, 2020
Title Compositions And Methods For Stabilizing Flaviviruses With Improved Formulations
Inventorship Jill Ann Livengood, Fort Collins, CO (US)
Linda Marie Strange, Framingham, MA (US)
Steven Michael Erb, Fort Collins, CO (US)
Assignee TAKEDA VACCINES, INC., Cambridge, MA (US)

Claim of US Patent No. 10,835,597

1. A flavivirus composition comprising:one or more live flaviviruses;
at least one of trehalose in a concentration ranging from 5.0% to 15.0% (w/v) and sucrose in a concentration ranging from 5.0% to 15.0% (w/v);
urea;
mannitol; and
human serum albumin.