US Patent No. 10,688,174

METHOD OF CONFERRING A PROTECTIVE IMMUNE RESPONSE TO NOROVIRUS


Patent No. 10,688,174
Issue Date June 23, 2020
Title Method Of Conferring A Protective Immune Response To Norovirus
Inventorship Charles Richardson, Cambridge, MA (US)
Thomas S. Vedvick, Cambridge, MA (US)
Thomas R. Foubert, Cambridge, MA (US)
William Tino, Cambridge, MA (US)
Assignee Takeda Vaccines, Inc., Cambridge, MA (US)

Claim of US Patent No. 10,688,174

1. A method of eliciting protective immunity to a Norovirus infection in a human comprising administering to the human a vaccine comprising at least two Norovirus virus-like particles (VLPs), wherein the at least two VLPs represent different Norovirus genotypes, wherein at least one Norovirus VLP is present in the vaccine in a dose amount of from about 1 ug to about 200 ug, and wherein the vaccine is able to elicit immunity against each Norovirus genotype represented in the vaccine.