US Patent No. 10,632,184

COMPOSITIONS AND METHODS FOR STABILIZING ALPHAVIRUSES WITH IMPROVED FORMULATIONS


Patent No. 10,632,184
Issue Date April 28, 2020
Title Compositions And Methods For Stabilizing Alphaviruses With Improved Formulations
Inventorship Jill Ann Livengood, Fort Collins, CO (US)
Timothy Duane Powell, Maynard, MA (US)
Assignee TAKEDA VACCINES, INC., Cambridge, MA (US)

Claim of US Patent No. 10,632,184

1. A live attenuated alphavirus composition comprising:one or more live alphaviruses;
one or more amino acids that include histidine;
two or more carbohydrate agents; andwherein the composition does not include serum or gelatin and wherein the composition stabilizes live alphaviruses.