US Patent No. 10,512,682


Patent No. 10,512,682
Issue Date December 24, 2019
Title Norovirus Vaccine Formulations
Inventorship Charles Richardson, Cambridge, MA (US)
Thomas S. Vedvick, Cambridge, MA (US)
Thomas R. Foubert, Cambridge, MA (US)
William T. Tino, Cambridge, MA (US)
Assignee Takeda Vaccines, Inc., Cambridge, MA (US)

Claim of US Patent No. 10,512,682

1. A method of generating an immune response to at least two Norovirus strains by administering to a patient an antigenic formulation comprising a combination of two or more monovalent Norovirus VLPs of different Norovirus genotypes, or an antigenic formulation comprising multivalent VLPs containing capsid proteins from two or more different Norovirus genotypes, such that the combination of VLPs within the formulation does not block the immunogenicity of each VLP type.