US Patent No. 10,363,232

COMPOSITIONS AND METHODS FOR TREATING SEVERE PAIN


Patent No. 10,363,232
Issue Date July 30, 2019
Title Compositions And Methods For Treating Severe Pain
Inventorship Robin M. Bannister, Essex (GB)
John Brew, Hertfordshire (GB)
Assignee Infirst Healthcare Limited, London (GB)

Claim of US Patent No. 10,363,232

1. A method of treating an individual with an inflammatory pain, the method comprising the step of: administering to the individual in need thereof a pharmaceutical composition, wherein the pharmaceutical composition comprises:a) a propionic acid derivative non-steroidal anti-pain drug (NSAID), or a pharmaceutically acceptable salt, solvate, or solvate of a salt thereof, in an amount of about 15% to about 30% of the total weight of the composition; and
b) a pharmaceutically-acceptable lipid in an amount of at least 50% of the total weight of the composition, the pharmaceutically-acceptable lipid comprising a pharmaceutically-acceptable triglyceride in an amount of at least 30% of the total weight of the composition, and a pharmaceutically-acceptable glyceride mixture including a monoglyceride, the pharmaceutically-acceptable glyceride mixture in an amount of at least 20% of the total weight of the composition,
wherein the pharmaceutical composition is formulated to be a solid at a temperature of about 15° C. or lower and have a melting point temperature of about 25° C. or higher.