1. A method for determining a prognosis in a subject diagnosed with a disorder associated with increased threonyl-tRNA synthetase (TARS) activity, the method comprising:(a) obtaining a biological sample from the subject;
(b) measuring a TARS molecule level in the subject's biological sample;
(c) comparing the TARS molecule level of the subject's sample with a control level of the TARS molecule;
(d) correlating levels of the TARS molecule at least 25% greater than the control level with an indication of unfavorable prognosis and levels of the TARS molecule at or below the control level with a favorable prognosis; and
(e) administering to the subject with an indication of unfavorable prognosis a treatment selected from the group consisting of one or more of a medicament, surgery, radiation and chemotherapy
(f) wherein, the disorder is selected from prostate cancer and ovarian cancer.