US Patent No. 10,036,068

DIAGNOSIS, PROGNOSIS, AND TREATMENT OF MYOCARDIAL INFARCTION


Patent No. 10,036,068
Issue Date July 31, 2018
Title Diagnosis, Prognosis, And Treatment Of Myocardial Infarction
Inventorship Olivier Boutaud, Nashville, TN (US)
Elias Haddad, Nashville, TN (US)
Assignee Vanderbilt University, Nashville, TN (US)

Claim of US Patent No. 10,036,068

1. A kit for diagnosis, prognosis, and treatment associated with a cardiovascular event and/or anti-platelet therapy in a subject, comprising:a set of two, three, or four single nucleotide polymorphism (SNP)-specific probes wherein each SNP-specific probe is selected from the group consisting of:
a probe for detecting Rs7541936 in PTGER3 in a sample obtained from the subject;
a probe for detecting Rs977214 in PTGER3 in a sample obtained from the subject;
a probe for detecting Rs2206343 in PTGER3 in a sample obtained from the subject; and
a probe for detecting Rs4383756 in PTGER4 in a sample obtained from the subject;
the kit including the probe for detecting Rs4383756 in PTGER4 in the set of probes and/or an EP3 receptor antagonist;
wherein the kit does not include any probes in addition to the set of probes; and
wherein the probes are fluorescently-labeled.