US Pat. No. 10,362,951

NON-INVASIVE METHOD AND SYSTEM FOR CHARACTERIZING CARDIOVASCULAR SYSTEMS

Analytics For Life Inc., ...

1. A method of pre-processing data to extract variables for use in a machine learning operation to diagnose a pathology, the method comprising:receiving a biopotential signal data set associated with a subject, said biopotential signal data set being associated with a biopotential signal collected from one or more electrical leads;
generating, via a processor, an estimated noiseless model of the received biopotential signal data set, wherein generation comprises iterative selection of member atoms of a pre-defined dictionary of member atoms to form a sparse approximation of the received biopotential signal data set;
extracting, via the processor, a plurality of features from a low-energy complex sub-harmonic subspace derived from the estimated noiseless model, wherein one or more of the plurality of extracted features includes one or more fractional derivative derived features of the low-energy complex sub-harmonic subspace; and
linking, via the processor, the one or more of the plurality of extracted features to a genetic algorithm to generate outputs that correlate with clinical parameters describing tissue architecture, structure and/or function.

US Pat. No. 10,362,950

NON-INVASIVE METHOD AND SYSTEM FOR MEASURING MYOCARDIAL ISCHEMIA, STENOSIS IDENTIFICATION, LOCALIZATION AND FRACTIONAL FLOW RESERVE ESTIMATION

Analytics For Life Inc., ...

1. A method for non-invasively identifying and/or measuring or estimating a degree of myocardial ischemia, identifying one or more stenoses, and/or localizing and/or estimating fractional flow reserve, the method comprising:obtaining, by one or more processors, a data set associated with a plurality of wide-band gradient signals simultaneously from the subject via at least one electrode;
generating, by the one or more processors, a residue subspace data set and a noise subspace data set from the data set associated with the plurality of wide-band gradient signals;
determining, via the one or more processors, one or more coronary physiological parameters of the subject selected from the group consisting of a fractional flow reserve estimation, a stenosis value, and a myocardial ischemia estimation, based on the residue subspace data set and the noise subspace data set; and
output, via one or more of an output data set in a report and/or a display, the one or more coronary physiological parameters, wherein the output is used in the diagnosis of cardiac disease.

US Pat. No. 10,362,947

PRESSURE SENSING DEVICES

INTEGRA LIFESCIENCES SWIT...

1. A pressure sensing catheter, comprising:an elongate body having
a sidewall defining an inner lumen extending at least partially therethrough,
a distal portion configured to be disposed in a ventricle of a brain, the distal portion including a microchip embedded in the sidewall and having a pressure sensor formed therein, at least a portion of the pressure sensor being exposed to an external environment surrounding the elongate body such that the pressure sensor is effective to measure a pressure of the external environment,
at least one fluid-entry port formed in the elongate body proximal to the pressure sensor, the at least one fluid-entry port being in fluid communication with the inner lumen,
an antenna located at a proximal portion of the elongate body and coupled to the microchip, the antenna being adapted to wirelessly communicate the measured pressure from the pressure sensor to an external device,
an elongate slot formed in an exterior surface of the sidewall of the elongate body, the elongate slot having a proximal terminal end in the sidewall at a location that is distal to a proximal end of the elongate body, and
a connector seated in the elongate slot, the connector having a first terminal end at the microchip and a second terminal end at the antenna, the connector between its first and second terminal ends being exposed to the external environment surrounding the elongate body, the antenna and the connector being removable from the elongate body.

US Pat. No. 10,362,945

METHOD AND DEVICE FOR ASCERTAINING A BLOOD PRESSURE CURVE

CIS FORSCHUNGSINSTITUT FU...

1. A method for ascertaining the time-dependent curve of the blood pressure including the following steps:noninvasive detection of time-dependent and volume-dependent blood flow values, in the form of photoplethysmographic values P(t), in a section of tissue with blood circulation by means of a photoplethysmographically functioning sensor;
transformation of the photoplethysmographic values P(t) into blood pressure values B(t) through the use of the following transformation formula by means of a data processing unit:

determining the time interval between the occurrences of the first two peaks in the curve of the transformed blood pressure values B(t) within a signal period by means of the data processing unit;
outputting of the transformed blood pressure values B(t) as time-dependent blood pressure values to a display and/or memory unit; and
generating a warning signal if the time interval falls below a predetermined minimum time interval in order to signal a critical blood pressure by means of a signal output unit.

US Pat. No. 10,362,940

PERSONAL EMERGENCY RESPONSE (PER) SYSTEM

Empire IP LLC, Austin, T...

1. A wearable monitoring apparatus, comprising:a housing adapted to be worn by a person on a wrist of the person;
an accelerometer disposed in the housing;
a processor disposed in the housing;
a user input device disposed on the housing;
wherein the user input device is adapted for selecting a predefined exercise,
and wherein the processor computes activity data for the selected predefined exercise based on signals from the accelerometer.

US Pat. No. 10,362,933

OPHTHALMOLOGIC APPARATUS, TOMOGRAPHIC IMAGE GENERATION METHOD, AND PROGRAM THAT DETERMINE AN IMAGING REGION FOR CAPTURING A PLURALITY OF TOMOGRAPHIC IMAGES FOR GENERATING AN AVERAGED TOMOGRAPHIC IMAGE

Canon Kabushiki Kaisha, ...

1. An ophthalmologic apparatus comprising:a detection unit configured to detect a movement amount of a subject's eye;
an error obtaining unit configured to obtain a value of tracking error based on a result of the detection;
a determining unit configured to determine each position of a plurality of scanning lines at intervals corresponding to the value of tracking error;
a tomographic image obtaining unit configured to obtain a plurality of tomographic images by scanning each position of the plurality of scanning lines with measurement light; and
a generation unit configured to generate an averaged tomographic image by averaging pixel values of the plurality of tomographic images obtained by the tomographic image obtaining unit,
wherein the determining unit determines the intervals based on the value of tracking error.

US Pat. No. 10,362,925

DOSING DEVICE FOR DISPENSING A WASHING AGENT IN A WASHING MACHINE, IN PARTICULAR A DISH WASHING MACHINE

BITRON S.P.A., Turin (IT...

1. A dosing device for dispensing doses of a washing agent, towards a washing chamber of a washing machine, comprising:a hollow body oscillatable between a loading position and a vertical, operating position, and in which there are defined:
a main chamber adapted to contain an amount of said washing agent corresponding to a plurality of doses, and
a dosing chamber adapted to contain a volume of washing agent substantially corresponding to one dose, coming from the main chamber; and
an electrically controlled valve obturator driven in each cycle of operation of the machine by a first short pulse for the actuation of another function, and thereafter with a subsequent second long pulse in order to put the dosing chamber in communication with the main chamber and thereafter cause the dispensing of a dose of washing agent from the dosing chamber towards the washing chamber,
wherein in the hollow body there are further defined:
an auxiliary chamber adapted to contain an amount of said washing agent corresponding to a multiplicity of doses, and
an intermediate chamber comprising an upper end and a lower end, the intermediate chamber being disposed between the auxiliary chamber and the dosing chamber, and communicating permanently with the auxiliary chamber at the lower end of the intermediate chamber,
wherein a communication passage is defined between the intermediate chamber and the dosing chamber, wherein the dosing chamber comprises a dispensing opening, and wherein said valve obturator is movable in the dosing chamber between a position opening, and a second position in which the valve obturator opens said communication passage and closes said dispensing opening,
wherein the communication passage is located at the upper end of the intermediate chamber, under a top wall delimiting the upper end of the intermediate chamber,
wherein the intermediate chamber is adapted to:
trap an air bubble when said hollow body oscillates from the loading position to the vertical, operating position, and
discharge a washing agent contained therein towards said auxiliary chamber when the hollow body oscillates from the vertical, operating position to the loading position, and
wherein said valve obturator controls the communication between the intermediate chamber and the dosing chamber such that said first pulse causes the intermediate chamber to be put in communication with the dosing chamber for a short time, causing a partial discharge of said air bubble from the intermediate chamber to the dosing chamber and a corresponding increase of the amount of washing agent contained in the intermediate chamber, and said second pulse causes the intermediate chamber to be put in communication with the dosing chamber for a relatively longer time, sufficient to allow the storing of a dose of washing agent in the dosing chamber and, when said second pulse is over, the dispensing of said dose of washing agent stored in the dosing chamber.

US Pat. No. 10,362,918

SELF-PROPELLED AND SELF-STEERING FLOOR CLEANER AND METHOD FOR CLEANING A FLOOR SURFACE

robart GmbH, Linz (AT)

1. A self-propelled and self-steering floor cleaner comprising a cleaning device with at least one cleaning unit for cleaning a floor surface of a room, at least a section or sections of an obstacle located inside the room not being in contact with the floor surface, the obstacle being of such low height that the floor cleaner cannot move under the obstacle, the floor cleaner further comprising a transmission unit for emitting radiation directed at the obstacle and the floor surface, in order to spatially scan these, a detection unit for detecting reflected radiation and providing a detection signal relating thereto, a control unit coupled to the detection unit, and a chassis for movement on the floor surface comprising a drive unit coupled to the control unit, it being determinable by the control unit from the detection signal whether a space is present between the obstacle and the floor surface, if so, a floor surface section located underneath the obstacle being regarded as cleanable, and the drive unit being actuatable to move the floor cleaner for cleaning the floor surface section, with at least one cleaning unit reaching into the space,wherein the drive unit is actuatable to move the floor cleaner during cleaning of the floor surface section at a predetermined or predeterminable distance from the obstacle.

US Pat. No. 10,362,899

BARBECUE GRILL ACCESSORY AND METHOD FOR PREPARING FOOD

Adrenaline Barbecue Compa...

1. A grilling insert adapted for use in a barbecue grill having a recessed cooking chamber, said grilling insert comprising:a double-wall thermal barrier adapted for extending across the recessed cooking chamber of the barbecue grill, and dividing the cooking chamber into direct-heating and indirect-heating cooking sections, and said thermal barrier comprising a chordal water reservoir designed to extend from one point on a circular interior of the recessed cooking chamber to an opposite point, and wherein said thermal barrier has an asymmetrical V-shaped vertical cross-section with a first vertical wall of said thermal barrier being longer than a second vertical wall of said thermal barrier; and
a radiant heat chamber adjacent said double-wall thermal barrier, and designed for holding loose combustible material within the direct-heating cooking section of the barbecue grill, such that cooking temperature in the direct-heating cooking section is relatively high, and is reduced in the indirect-heating cooking section by said double-wall thermal barrier, and said radiant heat chamber comprising a vertical downwardly tapered peripheral wall curving between opposite ends of said thermal barrier and designed to reside proximate an interior surface of the barbecue grill, and said peripheral wall cooperating with said thermal barrier to define a relatively large open top of said heat chamber and a comparatively small bottom of said heat chamber.

US Pat. No. 10,362,890

METHOD FOR SIMULTANEOUSLY PEELING AND CUTTING COOKED VEGETABLES

Hosam Khalil Smiley, New...

1. A method for peeling, and cutting a cooked root vegetable comprising providing a cooked root vegetable having flesh and skin wherein same has been cut in half to provide cut surfaces; placing said cut in half and cooked root vegetable on a movable surface with the cut surface facing upward, said surface existing within a frame, said frame having front, rear and side surfaces so as to receive the cut in half and cooked root vegetable, said surface associated with the frame to enable said surface to move within the frame linearly and reciprocally along at least a portion of the height of the frame; fixing a mesh plate to the frame above said surface, the mesh plate oriented perpendicular to the movement of said surface; and providing power to enable said surface to move toward the mesh plate, whereby said surface moves the cut in half and cooked root vegetable through the mesh plate, such that said flesh of the cut in half and cooked vegetable is cut and the skin remains behind the mesh plate after all of said flesh has been fed through said mesh plate.

US Pat. No. 10,362,889

RECEPTACLE FOR RECEIVING AND SECURING PACKAGES AND OTHER ITEMS

BENCHSENTRY INC., Little...

1. A receptacle that is positionable on a porch or other area of a home and that is configured for securing a package, the receptacle comprising:a bottom panel;
four side panels that are coupled with the bottom panel and that are coupled together to form an exterior wall that extends upward from the bottom panel and that defines an interior space within which the package is positionable, wherein opposing ends of each panel of said four side panels include at least one interfacing member having a through hole, the interfacing members being arranged so that as the ends of the four side panels are assembled, the through holes of adjacent interfacing members are axially offset, and wherein said four side panels are coupled together via insertion of a rigid rod member through the through holes of the adjacent interfacing members, wherein said insertion of said rigid rod member axially aligns the through holes of the adjacent interfacing members and thereby increases a mating engagement of adjacent side panels and increases a rigidity of the receptacle;
a lid that is pivotably coupled with a back panel of said four side panels via a hinge mechanism, the lid being configured to cover an opening at a top end of the receptacle to enclose the package within the interior space, wherein the lid is configured to be pivoted open to enable the package to be removed from the interior space, and wherein the hinge mechanism is positioned relative to said four side panels so that a pivot point of the hinge mechanism is positioned above a top surface of the lid and is positioned forward of a rear surface of the back panel; and
a lock mechanism that is operably coupled with the lid and the exterior wall of the receptacle, the lock mechanism having a locked state in which the lid is locked and secured about the top end of the receptacle to prevent user access to the interior space and the lock mechanism having an unlocked state in which the lid is pivotable open to allow user access to the interior space; wherein:
a seam between each adjacent panel is covered and concealed by a component of the exterior wall so that the seam is not readily user accessible;
a vertical lip of the lid overlaps at least three sides of the top end of the exterior wall so that a seam between the lid and the top end of the exterior wall is covered by the lip.

US Pat. No. 10,362,887

APPARATUSES AND METHODS FOR PLACING A COVERING ABOUT A MATTRESS

Russo Inventions, LLC, G...

1. A tool for manipulating a bed covering, comprising:a proximal handle portion;
a distal end portion comprising a plurality of spaced-apart protrusions extending outwardly therefrom, wherein the spaced-apart protrusions are configured to engage and extend through a plurality of openings in said bed covering to manipulate said bed covering; and
end stop portions disposed directly adjacent to the spaced-apart protrusions sized and configured for abutting with said bed covering adjacent to the openings of said bed covering to limit how far the protrusions can extend through the openings.

US Pat. No. 10,362,883

UNITARY, CONTINUOUS AND LINEAR APPARATUS HAVING DUAL FUNCTIONALITY FOR TRANSPORTING AND SECURING COVER TO A SEATING OR RESTING DEVICE

Leann L. Bellini, Dixon,...

1. An apparatus for transporting a cover and for securing said cover to a seating or resting device comprising:a) a linear strap, wherein said linear strap further comprising:
i) a left strap,
ii) a stabilizing pad, wherein said stabilizing pad further comprises a first quilt stitching and a second quilt stitching, and
iii) a right strap,
b) a first fastening means for engaging a first end of said linear strap to said linear strap to form a first closed-loop of variable size to secure towel during transportation,
c) a second fastening means for engaging a second end of said linear strap to said linear strap to form a second closed-loop of variable size for use as a transportation sling, and
d) a variable coupling means for configuring said linear strap into a third closed-loop of variable size for securing said cover disposed on said seating or resting device.

US Pat. No. 10,362,881

COLLAPSIBLE, FOLDING MATTRESS SUPPORT WITH A HEADBOARD AND A FOOTBOARD THAT FOLD OUT

Best Price Mattress Inc.,...

1. A foldable mattress support comprising:a bedboard frame with a first portion and a second portion;
a central hinge portion that is pivotally attached to the first portion and the second portion;
a headboard frame; and
means for rotating the headboard frame from a collapsed state that is parallel and adjacent to the first portion to an unfolded state that is perpendicular to the first portion without pivoting the headboard frame about any axis whose position is fixed with respect to the first portion.

US Pat. No. 10,362,879

BED FRAME ASSEMBLED BY SLIDING THE ENDS OF HOLLOW METAL BARS INTO NARROW SLOTS CUT INTO OTHER METAL BARS

Zinus Inc., Tracy, CA (U...

1. A mattress support comprising:a first hollow bar with a rectangular cross section, a first end and a first slot, wherein the first hollow bar is made from metal having a first thickness;
a second hollow bar with a rectangular cross section, wherein a second slot is disposed in two adjacent sides of the second hollow bar, wherein the second slot has a first width that is greater than the first thickness but less than twice the first thickness, wherein a third slot is disposed in the two adjacent sides of the second hollow bar, and wherein the first end of the first hollow bar is adapted to be inserted into the second slot; and
a third hollow bar with a rectangular cross section and a top end, wherein the third hollow bar is made from metal having a second thickness, wherein the third slot has a second width that is greater than the second thickness but less than twice the second thickness, and wherein the top end of the third hollow bar is adapted to be inserted into the first slot and the third slot.

US Pat. No. 10,362,875

EASY FOLDING CROSS BRACE DESIGN

GCI OUTDOOR, INC., Higga...

1. An apparatus comprising:first and second U-shaped cross-members, each of said cross-members including a front portion, a rear portion, and a cross bar perpendicularly connecting the front portion to the rear portion, wherein the respective front portions of the first and second cross-members are pivotally connected with each other at central portions thereof and the respective rear portions of said cross-members are pivotally connected with each other at central portions thereof,
wherein the cross-members are mutually movable from a generally X-shaped set-up condition in which the cross bars of the first and second cross-members are transversely spaced apart, to a generally flat collapsed condition in which the cross bars of the first and second cross-members are generally adjacent one another; and
right and left frame side assemblies are pivotally connected to each of the first and second cross-members, wherein at least one of the right and left frame side assemblies is pivotally connected to one of the first and second cross-members by a lost motion linkage;
wherein said lost motion linkage comprises a longitudinal link having a first end pivotally connected to one of the first and second cross-members via a first pivot pin and a second end pivotally connected to the at least one of the right and left frame side assemblies via a second pivot pin, said longitudinal link further comprising a slot extending partially along a length of the link proximate at least one of the first end and the second end and in which the first pivot pin or the second pivot pin is received for sliding movement within said slot with movement of the cross-members between the set-up condition and the collapsed condition.

US Pat. No. 10,362,872

FOLDING DRAWER FOR CABINET

E-MAKE CO., LTD., Taichu...

1. A folding drawer for cabinet, comprising:a bottom board including a plurality of holes in a front end;
two side panels each including a plurality of holes in a front end, a slide on an outer surface, and an L-shaped positioning member on a top of a rear end;
a rear panel including two U-shaped grooves on two sides respectively, and two flexible projections each adjacent to the U-shaped groove wherein the L-shaped positioning member is configured to dispose in the U-shaped groove;
a front panel including a plurality of holes in a lower portion of a rear surface;
a plurality of pins each having two ends fitted in either the hole of the front panel and the hole of the bottom board respectively or the hole of the front panel and the hole of either side panel respectively; and
first, second and third hinges wherein the first hinge is disposed on a joining portion of a rear surface of the rear panel and a bottom of the bottom board, the second hinge is disposed on a joining portion of an inner surface of one side panel and a top of the bottom board, and the third hinge is disposed on a joining portion of an inner surface of the other side panel and the top of the bottom board.

US Pat. No. 10,362,866

METHODS FOR CONTROLLED DISPENSING

Cubex LLC, Phoenix, AZ (...

1. A method for selective actuation, comprising: translating an index plate in a first direction in proximity to a plurality of bins arranged relative to one another in a plurality of columns of bins and each having a corresponding trigger release arm, wherein the index plate defines a plane having a perimeter border and a plurality of protrusions extending from a surface of the plate entirely within the perimeter border of the plane such that the plurality of protrusions are non-planar relative to the index plate and where the plurality of protrusions define a plurality of rows arranged upon the plate in a collinear arrangement; aligning a single protrusion to a single trigger release arm along the first direction; and translating the index plate in a second direction transverse to the first direction such that the single protrusion engages with the single trigger release arm and actuates a preselected bin which corresponds to the single trigger release arm, wherein the plurality of protrusions further define a plurality of columns which are arranged upon the plate at an angle relative to a proximal or distal edge of the plate such that each protrusion is off-set relative to an adjacent protrusion along the plurality of columns of protrusions which are further arranged to actuate alternating columns from the plurality of columns of bins for dispensing.

US Pat. No. 10,362,865

SECURABLE AND COLLAPSIBLE WORK STATION

JPL Investments, LLC, Sa...

1. A securable work station comprising:a base portion comprising a housing having a bottom, a first side, an opposing second side, a front, a back and a top, and a generally planar work surface located at said top of said housing;
an upper portion movably mounted relative to said base portion, said work-bench portion having a first side, an opposing second side, a front, a back and a top and defining an interior area, said work-bench portion configured to move between a first lowered position in which said first side, said opposing second side, said front, said back and said top of said upper portion extend over and cover said first side, said opposing second side, top front, said back and said top of said base portion whereby said housing of said base portion located within said interior area of said upper portion, whereby said securable work station has a first height, and a second raised position in which said upper portion is raised upwardly relative to said base portion and said securable work station has a second height which is greater than said first height and said interior area of said upper portion defines a generally open work space above said generally planar work surface; and
an upper portion lift assist mechanism, said lift assist mechanism comprising at least one biasing mechanism which biases said upper portion upwardly relative to said base portion, said biasing mechanism being user-adjustable whereby a biasing force generated by said at least one biasing mechanism is modifiable by a user.

US Pat. No. 10,362,853

SWIVEL LIP APPLICATOR

CONCEPT WORKSHOP WORLDWID...

1. An applicator comprising:a body having a first top surface including an opening, a channel extending through the body away from the opening of the first top surface, and a first side and a second side including a first slot and a second slot respectively cut through the first and second sides;
a cover having a second top surface, a first arm and a second arm extending away from the second top surface, and a first and second hinges installed on the first and second arms respectively;
a support cup having a side wall, an inner-body opening configured to receive a product, and first and second recesses inscribed on opposite sides of the side wall; and
an indentation or hole on at least one of the first and second sides of the body and a peg on at least one of the corresponding first and second arms of the cover such that when the indentation or hole engages with the peg, the cover is prevented from moving longitudinally with respect to the body,
wherein the support cup is slidably fitted inside the channel of the body and the cover is hingedly coupled to the body via the first and second hinges of the cover,
wherein the first and second hinges protrude through the first and second slots of the body and engage with the first and second recesses of the support cup, respectively, and the cover and the support cup are slidable together in a longitudinal direction along the channel of the body, and
wherein the body is configured to allow the cover and support cup to slide in the longitudinal direction only after the cover is rotated away from a position in which the opening is covered.

US Pat. No. 10,362,852

ERGONOMIC MANICURING SUPPORT

Lori Ellen Halloway, Sal...

1. An ergonomic manicuring support apparatus comprising:an angled ramp including a top edge, a bottom edge wider in length than the top edge and opposing side edges extending between the bottom edge and the top edge, wherein the angled ramp is configured to receive and support at least one forearm and at least one wrist of a user;
a platform including a top edge, a bottom edge wider in length than the top edge and connected to the top edge of the angled ramp and opposing side edges extending between the bottom edge and the top edge, wherein the platform is configured to receive and support at least one hand of the user;
at least one contoured convex hand support disposed proximate at least one opposing side edge of the platform, wherein the at least one contoured convex hand support is configured to support and prevent movement of the at least one hand of the user;
a pair of legs connected to and supporting the angled ramp and the platform, wherein the pair of legs are connected to a portion of the platform to allow the top edge of the platform to extend from the legs; and
support brackets extending between the pair of legs to structurally reinforce the angled ramp and the platform,
wherein the at least one forearm, wrist and hand of the user are positioned and supported by the angled ramp and at least one contoured convex hand support on the platform to elevate the at least one wrist and the at least one hand of the user and position one or more fingers of the user in a hanging downward position relative to the top edge of the platform to receive manicuring services.

US Pat. No. 10,362,844

MOVABLE DECORATIVE ELEMENTS

CHOPARD TECHNOLOGIES SA, ...

1. A decorative article comprising a movable decorative element which is freely mounted in rotation and translation between two walls (5, 6) whose inner faces are parallel to each other, at least one of which is transparent, the decorative element including a precious or semi-precious stone (2) mounted in a socket (1), the socket (1) including:a closed bottom (4), having an outer face (7) which is applied in contact against the inner face of one of said walls, with one of the contacting faces bulged to promote the rotation of the decorative element, and
an open outer face (7) opposite to the bottom (4) which is flush with or protrudes relative to the stone (2) to form a bearing surface against the other of said walls (5, 6),
characterized in that the precious or semi-precious stone (2) is held in said socket (1) by a plurality of arms (3) integral with the socket (1) and extend above a body (8) of the socket (1) terminating at a free end, crimp the stone (2), the body (8) of the socket with said plurality of integral arms (3) being closed by said closed bottom whose outer face in contact with said inner face of the other of said walls promotes the rotation of the decorative element, said arms (3) leaving, therebetween and above the body (8) of the socket (1), lateral openings (9) which are rotatable with the socket (1) and which let appear flanks of the stone (2) between the arms (3) during rotation of the decorative element, and said bearing surface is constituted by free ends of said arms (3) in the form of separate contact areas spaced from each other around the open outer face (7) of the socket (1) about a periphery thereof, the free ends of said plurality of arms (3) being able to come to bear against the other of said walls when the decorative element rotates and translates between the two walls.

US Pat. No. 10,362,841

ORNAMENT

MARIND CO., LTD., Osaka-...

1. An ornament comprising:an ornament body which is provided with a receiving portion;
a pivot shaft provided in erect fashion, and engaging the receiving portion in such manner that only a bottom end portion of the pivot shaft makes contact with said receiving portion;
a rigid suspending arm portion that protrudes from a top end portion of said pivot shaft; and
a jewelry member supported by a lower portion of said suspending arm portion;
wherein said pivot shaft, said suspending arm portion, and the jewelry member supported in pendant fashion by the lower portion of said suspending arm portion are formed in integral fashion; and
said pivot shaft is capable of swinging about a contact point of said receiving portion.

US Pat. No. 10,362,837

CLOSURE APPARATUS

Fastech Asia Worldwide, L...

1. A closure comprising:a male closure member comprising:
a first loop;
an arm fixedly attached to the first loop;
a bar fixedly attached to the arm, the bar having an upper portion extending orthogonally from the arm in a first direction and a lower portion extending orthogonally from the arm in a second direction opposite the first direction; and
a first loop extension fixedly attached to the first loop and extending orthogonally from the first loop in the second direction; and
a female closure member comprising:
a second loop; and
a base portion fixedly attached to the second loop, the base portion comprising:
a top edge;
a bottom edge;
a blind hole extending from the top edge toward the bottom edge into which the bar of the male closure member is insertable at the top edge and moveable along and configured for rotational pivoting of the bar in the blind hole;
a resilient protrusion disposed in and extending from the base portion at a position proximal to the bottom edge and configured to secure the first loop extension upon insertion and rotation of the bar in the blind hole; and
a recess configured to receive the arm attached to the bar inserted in the blind hole and positioned such that the upper portion of the bar and the lower portion of the bar are disposed between the top edge and the bottom edge.

US Pat. No. 10,362,828

HEADBAND ARRANGEMENT AND WELDING HELMET EQUIPPED WITH THE SAME

Tecmen Electronics Co., L...

1. A headband arrangement for a welding helmet, comprising:a fixed attachment structure; and
a helmet mounting structure cooperating with the attachment structure and comprising a lockable component,
wherein:
at least two stopping positions are defined longitudinally between the attachment structure and the helmet mounting structure,
the helmet mounting structure is selectively switchable between an unlocking state and a locking state,
in the unlocking state, the helmet mounting structure is slidable between the at least two stopping positions relative to the attachment structure, and
in the locking state, the helmet mounting structure is locked to one of the at least two stopping positions relative to the attachment structure and is adapted to be held at one of the at least two stopping positions by a magnetic force generated between a pair of magnetic parts the pair of magnetic parts comprising a first magnetic part secured on the lockable component and a second magnetic part, the second magnetic part secured on the helmet mounting structure or the attachment structure.

US Pat. No. 10,362,827

HEADGEAR ACCESSORY ATTACHMENT APPARATUS

Bryan Family Enterprises ...

1. A helmet accessory attachment apparatus adapted to be secured to the helmet, the helmet accessory attachment apparatus comprising:a band member comprising a central opening for receiving the helmet and at least one size adjustment member for adjusting the size of the flexible band member from a resting configuration, to an active configuration when the band member is fitted onto the helmet and the size adjustment feature is locked;
an accessory connector located on the band member for mounting a helmet accessory to the band member;
wherein the band member is sufficiently flexible to be manipulated from a floppy state in the resting configuration to a taut state in which the band member forms a secure clamp around a front edge of the helmet when the band member is fitted about the helmet and the size adjustment feature is locked, thereby prohibiting the apparatus from rising or rotating upwards on the helmet.

US Pat. No. 10,362,823

EYELASH EXTENSION CASE

Jessica Hill, Philadelph...

1. An eyelash extension case, comprising:an enclosure body defining a first internal region for storage of one or more eyelash extensions; and
a lid operative to cover the first internal region in a closed state and open to allow access to the first internal region in an open state;
wherein internal wall surfaces of the first internal region form a floor, and one or more eyelash extension retaining features,
each eyelash extension retaining feature including a protrusion that extends outward from the floor toward the lid along an axis,
each protrusion having curved wall surfaces that transition into the floor, and each protrusion having curved wall surfaces that define an outer profile of the protrusion surrounding the axis, and
wherein at least a portion of each protrusion is formed from a self-adhesive super-gel material to retain the one or more eyelash extensions
wherein the enclosure body is formed from two enclosure body halves that collectively define a second internal region.

US Pat. No. 10,362,821

OPENABLE GIFT PACKAGING DEVICE

Imprint Diamond Corp., S...

1. A gift packaging device comprising:a support device including a support member, a bore formed in said support member;
a stem slidably received and engaged through said bore of said support member and moveable up and down relative to said support member, said stem including an upper portion located above said support member,
a carrier member disposed on said stem for supporting a gift,
a plurality of flaps pivotally attached to said support member and rotateable relative to said support member between a folded position where the gift is covered and shielded with said flaps, and an opened position where the gift is viewable, and
a plurality of links coupled between said stem and said flaps for allowing said flaps to be rotated relative to said support member between said folded position and said opened position when said stem is moved relative to said support member of said support device, wherein
said support member includes a plurality of protrusions extended from said support member, and said flaps each include a stud pivotally attached to said protrusions of said support member.

US Pat. No. 10,362,818

UTILITY GLOVE

MADGRIP HOLDINGS, LLC, E...

1. A method of manufacturing a utility glove having a thumb, four fingers and a main body, said glove comprising a three dimensional molded portion, the molded portion comprising an elastomeric material bonded to a fabric material in a three dimensional configuration substantially conforming to three dimensional contours of at least a portion of a hand exclusive of any variations in thickness or features on the surface of the molded portion, comprising the steps of:a. placing a glove blank comprising a fabric material over a first mold part in the form of at least a portion of a hand;
b. bringing a second mold part into molding engagement with the first mold part to create a cavity with only a portion of the glove blank on the first mold part; and
c. injecting an elastomeric material into the cavity to form a molded portion, said molded portion having a thickness of from about 0.8 mm to about 10.8 mm with the elastomeric material on the fabric of the molded portion having a thickness of from about 0.4 mm to about 10.0 mm, wherein the elastomeric material of the molded portion is integrally formed to continuously extend up to and including 360° about the main body of the glove while leaving a portion of the fabric material of the glove blank without elastomeric material entirely surrounded by the molded portion.

US Pat. No. 10,362,815

ANTI-GRIP KIMONO

Lime Enterprises Limited,...

1. A reinforced martial arts kimono containing anti-grip reinforced panels which pop-off or release from the grip of an opponent grabbing the reinforced martial arts kimono, the reinforced martial arts kimono comprising:a kimono jacket that is formed from a first material;
the kimono jacket including right sleeve and right body portions;
the kimono further including left sleeve and left body portions and a collar;
the collar extending upwardly from upper ends of each of the left and right sleeves;
the right body portion includes an inner flap and the left body portion includes an outer flap;
each body portion includes a lapel which is contiguous with the collar;
the lapels extending downwardly from the collar toward the bottom of the kimono jacket;
wherein the lapel and inner flap of the right body portion extends under the lapel of the left body portion toward a left side of the wearer of the kimono jacket and the lapel and the outer flap of the left body portion extends over the inner flap of the right body portion and extends toward a right side of the wearer of the kimono jacket;
and the lapels and body portions are configured to be kept in place by a martial arts belt;
at least two anti-grip reinforcement panels affixed to an inside surface of the interior of the reinforced martial arts kimono;
the at least two reinforcement panels being located on the inside of the kimono form annular-shaped anti-grip reinforcement panels and the at least two reinforced panels are affixed to the inside of the sleeves of the reinforced anti-grip martial arts kimono jacket, adjacent to the cuffs of the each of the sleeves;
the at least two anti-grip reinforcement panels being of a second material which is different material than the first material forming the kimono jacket, the two reinforcement panels providing a sufficient popping-off tactile sensation or release of grip of an opponent grabbing the reinforced anti-grip martial arts kimono during the practice of martial arts;
and
wherein the second material adjacent to the cuff of each of the left and right sleeves extends from the cuff upwardly toward the collar of the anti-grip martial arts kimono jacket.

US Pat. No. 10,362,811

SOCK WITH SUPPORT ASSEMBLAGE

SOKSYSTEM, LLC, Beverly ...

1. A sock, comprising:a sock body defined by a toe section, a heel flap, a sole extending between the toe section and the heel flap on a bottom portion of the sock, and an instep extending between the toe section and the heel flap on a top portion of the sock, the toe section and the instep having a first elasticity coefficient;
an arch support assemblage, situated below the instep, in front of the heel flap, and behind the toe, the arch support assemblage adapted to cover an arch region of the sole of the sock excluding the toe section of the sock, the arch support assemblage having a second elasticity coefficient, wherein the second elasticity coefficient is lower than the first elasticity coefficient such that the arch support assemblage is stiffer than the toe, the heel flap, the instep, and the leg of the sock; and
an Achilles support assemblage, adapted to cover an Achilles tendon of a wearer of the sock when worn, the Achilles support assemblage running from a top edge of the heel flap to a top portion of a leg of the sock.

US Pat. No. 10,362,807

E-CIGARETTE PERSONAL VAPORIZER

AYR LTD., London (GB)

1. A re-fillable and re-chargeable inhalable vapor dispensing system including (i) a user-replaceable e-liquid reservoir for dispensing e-liquid and (ii) an e-liquid filling device; in which the reservoir is inserted into, or otherwise attached to, the e-liquid filling device and engages with an electrical or electronic fluid transfer system in the e-liquid filling device, the fluid transfer system being configured to transfer e-liquid from the e-liquid reservoir to a fluid storage chamber configured to supply e-liquid to an atomizing unit;and in which the reservoir is not user-refillable.

US Pat. No. 10,362,805

WICKLESS CARTOMIZER

Intrepid Brands, LLC, Lo...

1. A wickless cartomizer comprising:(a) a base;
(b) an outer wall extending from the base;
(c) an inner wall extending from the base;
(d) a vapor exit opening defined by the inner wall;
(e) a heating element disposed in the inner wall; and
an electrical connector disposed in the base, wherein the electrical connector is electrically coupled with the heating element.

US Pat. No. 10,362,798

ROASTING SYSTEM WITH CLEAN EMISSIONS AND HIGH THERMAL EFFICIENCY

Bellwether Coffee Co., B...

1. A bean roasting system, comprising:a roasting chamber coupled to a recirculating gas flow path;
a blower coupled to the recirculating gas flow path, the blower configured to provide a flow stream of gas through the recirculating gas flow path;
a variable diverter coupled to the recirculating gas flow path, the variable diverter configured to split the gas flow path into at least two flow paths including a treated flow path and a bypass flow path, the treated flow path including a series arrangement of a gas heater and a catalytic converter, the variable diverter configured to control a percentage of a flow stream of gas that is diverted into the bypass flow path; and
a controller configured to activate a plurality of different predetermined operating modes for the bean roasting system by controlling a state of the variable diverter and a state of the heater, gas flows out of the roasting chamber through the variable diverter and through the treated flow path and bypass flow path before returning to the roasting chamber along the recirculating flow path, the variable diverter is configured such that (1) the percentage of the flow stream of gas that is diverted into the bypass flow path controls a temperature in the roasting chamber as compared to a temperature in the catalytic converter, and (2) the temperature in the roasting chamber decreases relative to the temperature in the catalytic converter as the percentage of the flow stream of gas that is diverted into the bypass flow path is increased.

US Pat. No. 10,362,795

COLLAPSIBLE FOOD PREPARATION DEVICE

Alan Backus, Los Angeles...

1. A food preparation device using heated air, comprising:a heat source configured to heat air to food preparation temperatures;
a base enclosure configured to contain the heat source;
a first tray, stacked above the base enclosure, and including a generally flat floor configured to support foods to be processed, the floor being perforated to allow air passage from one side of the floor to the other side of the floor;
the floor being generally rectangular and comprising four generally straight edges;
the floor includes four generally planar hinged side walls, one each hinged to each of the four generally straight edges;
each of the four hinged side walls configured to rotate about its associated hinge axes from a generally horizontal disposition to a generally vertical disposition;
a second tray having substantially the same construction as the first tray,
the second tray configured to stack above the first tray when the four hinged side walls on the first tray are in their generally vertical dispositions;
wherein, when the heat source is activated during food preparation, the four hinged side walls on the first tray and the four hinged side walls on the second tray which is stacked above the first tray, are each in their vertical dispositions; and
wherein, when the heat source is not activated, and the device is not preparing food the four hinged side walls on the first tray and the four hinged side walls on the second tray are each oriented in their horizontal dispositions.

US Pat. No. 10,362,780

OXYGEN SUPPLY FOR ORGAN PERFUSION SYSTEMS

Organox Limited, Oxford ...

1. A perfusion system for the perfusion of an organ, the system comprising:a perfusion fluid circuit for circulating perfusion fluid through the organ;
an oxygenator for adding oxygen into the perfusion fluid, the oxygenator comprising a duct to carry the perfusion fluid, an oxygen chamber, and a permeable membrane between the duct and the oxygen chamber;
an oxygen supply arranged to supply oxygen to the oxygenator, wherein the oxygen supply comprises an oxygen concentrator, the oxygen concentrator comprising an inlet arranged to receive gas in the form of air, a compressor arranged in the inlet, and a nitrogen extractor arranged to extract nitrogen from the gas thereby to increase the oxygen concentration of the gas;
an air supply arranged to supply air to the oxygenator;
a carbon dioxide sensor arranged to measure a carbon dioxide content of the perfusion fluid;
an air control valve arranged to control the flow rate of air from an air supply to the oxygen chamber;
an oxygen control valve arranged to control the flow rate of oxygen from the oxygen concentrator to the oxygen chamber;
an oxygen sensor arranged to measure an oxygen content of the perfusion fluid; and
a controller arranged to define a first target range for said oxygen content, monitor the measured oxygen content and to control the oxygen control valve and the compressor in response to the measured oxygen content thereby to maintain the oxygen content within the first target range, and to define a second target range for said carbon dioxide content, to monitor the measured carbon dioxide content and to control the air control valve in response to the measured carbon dioxide content thereby to maintain the carbon dioxide content within the second target range.

US Pat. No. 10,362,773

AUTOMATIC RETRACTABLE FLOAT

RETRACT A FLOAT PTY LTD.,...

1. An automatic retractable float comprising:a body which floats in water;
the body comprising two halves connected to a central portion;
the central portion having a top handle, a pair of side handles and a line housing disposed about the outer surface, with a depression located under each side handle,
wherein about the outer surface of the central portion the line housing is positioned substantially opposite the top handle and the side handles are positioned substantially opposite each other such that each side handle is approximately midway between the top handle and the line housing and
wherein the line housing includes a conduit that passes through the outer surface of the central portion and provides access to an interior of the body;
each of the two halves having a pair of depressions positioned such that when each half is attached to the central portion, the pair of depressions are joined with the corresponding depression under each side handle;
an automatic retraction and extension mechanism contained within the interior of the body, the automatic retraction and extension mechanism including a spring mechanism for automatically extending and retracting a line from the body; and
at least one electronic device in communication with a mobile device such that the electronic device shares information or data with the mobile device.

US Pat. No. 10,362,765

PET TOY WITH SQUEAKER MECHANISM

Otomik Products, Inc., C...

1. An animal toy, comprising:a body member defining a cavity and including a sidewall, the sidewall defining a first opening in fluid communication with the cavity, the sidewall defining a second opening in fluid communication with the cavity, the first and second openings being disposed on an outer periphery of the body member, the first opening being different than the second opening; and
a squeaker member defining a lumen and configured to produce a sound in response to air passing through the lumen, the squeaker member being coupled to the body member such that at least a portion of the squeaker member is disposed within the cavity defined by the body member, the squeaker member including a switch configured to be moved from a first position to a second position, the switch being configured to prevent passing of air through the lumen when the switch is in the first position.

US Pat. No. 10,362,735

HARVESTING ATTACHMENT FOR A HARVESTER

BISO Schrattenecker GmbH,...

1. A harvesting attachment having a frame comprising:an elongated rear wall formed as an extrusion profile;
an elongated base wall formed as an extrusion profile;
an elongated curved connection wall curved in cross section formed as an extrusion profile;
wherein each of said rear wall, base wall and curved connection wall have a front wall and a back wall.

US Pat. No. 10,362,721

TILLAGE DEVICE FOR AGRICULTURAL MACHINERY OR IMPLEMENTS TO REDUCE COMPACTION CAUSED BY WHEELS IN A FIELD

AGRICULTURE CONCEPTS, LLC...

1. A system for tilling compression marks formed in soil of a field by agricultural machinery or equipment having a plurality of compaction forming members, the system comprising:a plurality of roller assemblies;
each of the plurality of roller assemblies having a plurality of blade assemblies positioned in spaced relation to one another;
each of the plurality of roller assemblies operatively connected to a frame member;
a plurality of row units;
wherein the plurality of row units are configured to plant seeds in the soil of the field;
wherein each of the plurality of roller assemblies are positioned between a pair of adjacent row units configured to plant seeds in the soil of the field;
wherein the plurality of roller assemblies are configured to rotate;
a movement device connected to each of the plurality of roller assemblies wherein when activated the movement device moves the associated roller assembly between a disengaged position, where the roller assembly does not penetrate the soil, and an engaged position, where the roller assembly does penetrate and till the soil;
each of the plurality of roller assemblies each having at least one guard positioned in spaced relation to the associated roller assembly;
wherein each guard is configured to deflect dirt that is kicked up during the tilling process;
wherein the plurality of roller assemblies are positioned behind and in alignment with a plurality of compaction forming members of the agricultural machinery or equipment;
wherein when the agricultural machinery or equipment moves through the field the compaction forming members form compression marks in the soil of the field;
wherein when in an engaged position, when the agricultural machinery or equipment moves through the field, the plurality of roller assemblies till the compression marks formed by the compaction forming members;
wherein when in an engaged position, when the agricultural machinery or equipment moves through the field, the plurality of roller assemblies till the compression marks formed by the compaction forming members the at least one guard associated with each roller assembly deflects dirt that is kicked up during the tilling process;
wherein positioning each of the plurality of roller assemblies behind and in alignment with a compaction forming member of the agricultural machinery or equipment facilitates tilling of the area behind and in alignment with the aligned compaction forming member while leaving the area between the compaction forming members untilled;
wherein the at least one guard associated with each roller assembly is configured to prevent dirt kicked up during the tilling process from landing outside of the tilled area which is behind and in alignment with the aligned compaction forming member.
US Pat. No. 10,363,303

MICRONEEDLE COMPOSITIONS AND METHODS OF USING SAME

VERNDARI, INC., Sacramen...

1. A microneedle device for administering a polypeptide, comprising:(a) a dehydrated composition comprising the polypeptide; and
(b) a substrate comprising a sheet and a plurality of microneedles extending therefrom, each microneedle of the plurality of microneedles comprising a tip, a base, a hinge at the base connecting the microneedle to the sheet, and a well comprising the dehydrated composition.
US Pat. No. 10,363,308

SELECTIVELY ALTERING MICROBIOTA FOR IMMUNE MODULATION

SNIPR Technologies Limite...

1. A method for treating a cancer in a patient, wherein the method comprises(a) exposing a microbiota in the patient to a guided nuclease to selectively target the genome of cells of a first species in the microbiota using the guided nuclease, wherein the first species is a bacterial or archaeal species; and simultaneously or sequentially administering to the patient an effective amount of an immunotherapy; and
(b) allowing the guided nuclease to cut one or more target nucleotide sequences comprised by first cells of a first strain of the first species, thereby killing the first cells or reducing the growth thereof, whereby the proportion of the first cells comprised by the microbiota is reduced;wherein(c) the selective targeting avoids targeting second cells comprised by the microbiota, wherein the second cells are of a different strain or a different species from the first cells; and
(d) the reducing of the proportion of the first cells modulates immune cells in the patient, whereby the efficacy of the immunotherapy is enhanced for treatment of the cancer in the patient.
US Pat. No. 10,364,332

HIGH TG EPOXY FORMULATION WITH GOOD THERMAL PROPERTIES

ISOLA USA CORP., Chandle...

1. A prepreg comprising a b-staged varnish composition including:a multi-functional epoxy wherein the multi-functional resin is not an eight-functional bisphenol-A novolac epoxy resin;
an eight-functional bisphenol-A novolac epoxy resin;
a bifunctional epoxy resin;
a hardener selected from 4,4?-diaminodiphenylsulfone, 3,3?-diaminodiphenylsulfone and mixtures thereof; and
decabromodiphenylethane wherein the prepreg is capable of being c-staged to a composite having a DMA Tg in excess of 280° C. and a T288 time in excess of 20 minutes.
US Pat. No. 10,364,336

THERMOPLASTIC VULCANIZATE COMPOSITION, METHOD OF FORMING THE SAME AND PRODUCT THEREOF

FENG TAY ENTERPRISES CO.,...

1. A method for forming a thermoplastic vulcanizate, comprising:selecting a thermoplastic polyurethane;
selecting a rubber, wherein a hardness of the thermoplastic polyurethane is 19A greater than that of the rubber; a hardness of the thermoplastic polyurethane is equal to or greater than 70A, and a weight ratio of the thermoplastic polyurethane to the rubber is between 30:70 and 70:30; and
mixing the thermoplastic polyurethane and the rubber in a dynamic vulcanization process, comprising:
forming a first mixture, wherein the first mixture comprises the rubber and an additive;
forming a second mixture, wherein the second mixture comprises a vulcanizing agent, an accelerator and the first mixture; and
forming a third mixture, wherein the third mixture comprise the thermoplastic polyurethane and the second mixture; and the step of forming the third mixture comprises a reaction process in a batch-type reactor at a temperature higher than 145° C. for at least 3 minutes or in a continuous-type reactor at a temperature higher than 190° C. for at least 15 seconds.
US Pat. No. 10,363,316

PHARMACEUTICAL FORMULATION COMPRISING NSAID AND CYCLODEXTRIN

RECKITT BENCKISER HEALTHC...

1. A liquid throat spray composition for topical application to a sore throat consisting essentially of an aqueous solution of at least 1% w/v of flurbiprofen, a cyclodextrin, and a pharmaceutically acceptable buffer,wherein the molar ratio of the NSAID to the cyclodextrin is between 1:0.5 and 1:1.5; and
wherein the composition is provided in a unit volume of up to about 2 ml.
US Pat. No. 10,363,319

GLYCOCONJUGATES AND METHODS FOR THEIR USE

THE BOARD OF REGENTS OF T...

1. A neoglycoconjugate comprising a trisaccharide coupled to a carrier, wherein the trisaccharide is Gal?(1,3)Gal?(1,4)GlcNAc?.
US Pat. No. 10,364,353

SILICONE RUBBER COMPOSITION AND SILICONE RUBBER CROSSLINKED BODY

SUMITOMO RIKO COMPANY LIM...

1. A silicone rubber composition comprising:(a) an organopolysiloxane;
(b) a crosslinking agent; and
(c) a microcapsule type catalyst that comprises microparticles of a resin and a crosslinking catalyst encapsulated in the microparticles,
wherein the resin of (c) has a solubility parameter of 7.9 or higher, a thermal conductivity of 0.16 W/m·K or higher, and a glass transition temperature of 40 to 145 degrees C.,
wherein the resin of (c) comprises at least one of an epoxy resin, an acrylic resin, a polyvinylbutyral resin, and a styrene based polymer,
wherein the acrylic resin comprises a copolymer of ethyl methacrylate and methyl methacrylate, and the styrene based polymer comprises any one of a copolymer of styrene and butadiene, a copolymer of styrene and maleic anhydride, a copolymer of styrene and isoprene, a hydrogenated styrene-butadiene copolymer, and a hydrogenated styrene-isoprene copolymer.
US Pat. No. 10,363,339

WATER ABSORBENT AGENT COMPOSITION AND METHOD FOR PRODUCING SAME, AS WELL AS STORAGE AND STOCKING METHOD FOR SAME

NIPPON SHOKUBAI CO., LTD....

1. A water absorbent agent composition comprising: a polycarboxylic acid (salt)-based water absorbent resin as a main component; a natural ingredient produced by a living organism; and a temporal deterioration preventing agent in an amount of 0.05 ppm to 120 ppm, wherein said temporal deterioration preventing agent is at least one of (a) a water-soluble reducing agent selected from the group consisting of erythorbic acid, L-ascorbic acid, and sulfites, (b) water-soluble oxidants selected from the group consisting of hypochlorous acids and hypochlorites, (c) phenylphenols, (d) benzoic acid or esters thereof, and (e) hydroxybenzoic acid or esters thereof, where the polycarboxylic acid (salt)-based water absorbent resin is a crosslinked polymer of unsaturated monomers, and the unsaturated monomers contain iron (Fe) in an amount of not more than 2 ppm based on the water absorbent agent composition.
US Pat. No. 10,367,190

CYLINDRICAL SINGLE-PIECE LITHIUM-ION BATTERY OF 400AH AND ITS PREPARATION METHOD

Tianjin University, Tian...

1. A method of making a cylindrical single-piece lithium-ion battery, comprising steps as follows:(1) mixing evenly LiFePO4, conductive carbon black, graphite, polyvinylidene fluoride as adhesive, and N-methylpyrrolidone as solvent in a weight percentage ratio of 42.0-43.0:1.3-1.7:0.8-1.2:2.5-3.5:51.0-53.0 to form a first slurry and mixing evenly lithium titanate, conductive carbon black, graphite, polyvinylidene fluoride as adhesive and N-methylpyrrolidone as solvent in a weight percentage of 49.0-50.0:0.8-1.2:0.8-1.2:3.0-4.0:44.0-46.0 to form a second slurry;
(2) coating and rolling the first slurry and the second slurry to form a positive electrode sheet and a negative electrode sheet, respectively, wherein each of the positive and negative electrode sheets is of a length of 33.81m, has an aluminum foil as current-collector and exposes a foil edge, and the aluminum foil has a thickness between 28 ?m and 32 ?m and a width between 319 mm and 321 mm;
(3) baking the positive electrode sheet and the negative electrode sheet for 48 hours at 100° C.;
(4) aligning and stacking up the positive electrode sheet and the negative electrode sheet with a separating membrane in-between, which are then mounted to an automatic winding machine to form a cylindrical shape;
(5) welding a plurality of aluminium tabs onto the foil edge of the positive electrode sheet and a plurality of aluminium tabs onto the foil edge of the negative electrode sheet, wherein each of the aluminium tabs has a length between 69 mm and 71 mm, a width between 9.9 mm and 10.1 mm and thickness between 0.135 mm and 0.165 mm;
(6) securing each of the aluminium tabs in a space defined by wiring terminal 6 and sliding ring 7 using tab clamping nut 8 to form a cell pack;
(7) inserting the cell pack into an enclosure with two ends each being wrapped by a supporting bracket;
(8) connecting sequentially wiring terminal 6, O-ring 10, insulation cushion 9 and cover 11 together, which are then fixed with clamping nut 12 and locating screw 13; and
(9) sealing cover 11 to the enclosure using a laser welder.
US Pat. No. 10,367,199

CATHODE ACTIVE MATERIAL, LITHIUM SECONDARY BATTERY HAVING SAME, AND METHOD FOR PREPARING SAME

Korea Electronics Technol...

1. A cathode active material for lithium secondary batteries which is represented by Chemical Formula 1 below and is obtained by coating a dissimilar metal (M) on a surface of a transition metal precursor comprising Ni, Co and Mn and then heat-treating the transition metal precursor together with a lithium source so that a portion of Ni, Co and Mn is substituted with the dissimilar metal (M):LiNiaCobMncMdO2  [Chemical Formula 1 ]
wherein 0.65?a ?0.7, 0
US Pat. No. 10,364,403

MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS

Chevron Oronite Technolog...

1. A marine diesel cylinder lubricating oil composition which comprises:(a) a major amount of one or more Group I basestocks, and
(b) a detergent composition comprising:
(i) about 5 to about 15 wt. % on an actives basis, based on the total weight of the marine diesel cylinder lubricating oil composition, of one or more alkaline earth metal salts of an alkyl-substituted hydroxyaromatic carboxylic acid having a total base number (TBN) of about 100 to about 250, wherein the alkyl-substituted moiety of the alkaline earth metal salt of an alkyl-substituted hydroxyaromatic carboxylic acid is a C12 to C28 alkyl group; and
(ii) about 5 to about 16 wt. % on an actives basis, based on the total weight of the marine diesel cylinder lubricating oil composition, of one or more high overbased calcium alkyl toluene sulfonic acids or salts thereof having a TBN of greater than 250 to about 550; wherein the toluene moiety of the calcium alkyl toluene sulfonic acids or salts thereof contains no hydroxyl groups, and further wherein the alkyl moiety of the calcium alkyl toluene sulfonic acids or salts thereof is a C12 to C40 alkyl group; and
wherein the marine diesel cylinder lubricating oil composition has a TBN of about 55 to about 80.
US Pat. No. 10,364,415

1,4-DIOXANE-DEGRADING BACTERIA CULTURE METHOD, MEDIUM, AND 1,4-DIOXANE TREATMENT METHOD USING 1,4-DIOXANE-DEGRADING BACTERIA

TAISEI CORPORATION, Toky...

1. A 1,4-dioxane-degrading bacteria culture method comprising culturing/incubating 1,4-dioxane-degrading bacteria with a medium containing diethylene glycol at a concentration of 1.0 wt % or more and 10.0 wt % or less, thereby multiplying the 1,4-dioxane-degrading bacteria, wherein the 1,4-dioxane-degrading bacteria are at least one of Mycobacterium sp. D11 (Accession Number: NITE BP-01926) or Pseudonocardia sp. D17 (Accession Number: NITE BP-01927).
US Pat. No. 10,364,419

HUMAN SERUM ALBUMIN BINDING COMPOUNDS AND FUSION PROTEINS THEREOF

Covagen AG, Zug (CH)

1. A nucleic acid molecule encoding a polypeptide binding to human serum albumin, wherein the polypeptide comprises an amino acid sequence selected from the group consisting of: SEQ ID Nos: 4 to 40.
US Pat. No. 10,364,426

PROCESS FOR REDUCING CELL DEATH AND INCREASING GROWTH OF AN ALGAL CULTURE

MISSING LINK TECHNOLOGY, ...

1. A process for reducing cell death and increasing growth of an algal culture, the process comprising:mixing the algal culture with water in a first reactor, the first reactor being a continuously stirred reactor, the step of mixing comprising:
continually circulating nutrients and the algal culture in a toroidal pattern and in a bottom-to-top pattern within said first reactor;
strobing light onto the mixture of algal culture and water for a period of time at a frequency of between 10 Hz and 40 Hz and between twenty flashes per second and eighty flashes per second;
flowing the strobed mixture of the algal culture and water from said first reactor for a period of time to a second reactor, the second reactor being a plug flow reactor, the step of flowing further comprising:
discharging the strobed mixture through a central drain of the first reactor to decrease fluid velocity of the strobed mixture and obtain a Reynolds Number (NRE) of less than 2000 is the second reactor;
discharging the strobed mixture from the second reactor; and
reducing cell death and increasing growth of said algal culture at a growth rate exceeding 120 grams/m2/day.
US Pat. No. 10,364,434

COMPOSITIONS AND METHODS OF BIOSYNTHESIZING CAROTENOIDS AND THEIR DERIVATIVES

ARCH INNOTEK, LLC, St. L...

1. A recombinant microorganism comprising a nucleic acid construct comprising:a) a nucleic acid sequence encoding a lycopene s-cyclase enzyme encoded by LCYe from Lactuca sativa; and
b) a nucleic acid sequence encoding a carotenoid cleavage dioxygenase enzyme encoded by CCD1 from Daucus carota:
wherein the nucleic add sequences are operably linked to one or more expression control sequences, and wherein the microorganism further comprises lycopene.
US Pat. No. 10,364,187

JAMB SPRAY MIXES INCLUDING FUSED SILICA AND METHODS OF UTILIZING THE MIXES

Resco Products, Inc., Pi...

1. A jamb spray mix comprising:0.1% to 10% phosphate by weight based on total weight of dry ingredients in the mix;
5% to 15% plasticizer based on total weight of dry ingredients in the mix;
the balance of dry ingredients including fused silica particles and impurities; and
at least 20% water by weight based on total weight of the mix.
US Pat. No. 10,364,444

SACCHAROMYCES CEREVISIAE YEAST STRAINS AND METHODS OF USE THEREOF

Microbiogen Pty. Ltd., S...

1. A process for producing ethanol from starch-containing material, the process comprising the steps of:i) liquefying the starch-containing material at a temperature above the initial gelatinization temperature using an alpha-amylase;
ii) saccharifying using a glucoamylase;
iii) fermenting using a fermenting organism;wherein the fermenting organism is:Saccharomyces cerevisiae MBG4930 (deposited under Accession No. V15/004035 at National Measurement Institute, Victoria, Australia);
Saccharomyces cerevisiae MBG4931 (deposited under Accession No. V15/004036 at National Measurement Institute, Victoria, Australia); or
Saccharomyces cerevisiae MBG4932 (deposited under Accession No. V15/004037 at National Measurement Institute, Victoria, Australia).
US Pat. No. 10,364,446

STREPTOMYCES PSAMMOTICUS AND METHODS OF USING THE SAME FOR VANILLIN PRODUCTION

XIAMEN OAMIC BIOTECHNOLOG...

1. A method for producing vanillin using Streptomyces psammoticus strain OMK-4 having preservation number CCTCC M 2015329, wherein the method comprises the steps of:1) strain activation;
2) seed culture; and
3) fermentation of ferulic acid to produce vanillinwherein strain activation step 1 comprises:under aseptic conditions, a full inoculation loop of strain OMK-4 from a glycerin stock tube is spread evenly over an agar slant and cultured in a biochemical incubator at 26-30° C. for 24-48 hours, and wherein by percentage of weight, the agar slant comprises the following components:soluble starch 1.0-3.5%, KH2PO4 0.1-1.0%, NaCl 0.05-0.3% and yeast extract powder 0.1-1.0%, andwherein seed culture step 2 comprises:under aseptic conditions, a full inoculation loop of well-grown OMK-4 cells from the ager slant in step 1 is inoculated into a seed culture medium having an initial pH value of 5-8 and cultured at 28-35° C. with 200-500 rpm shaking until exponential growth phase, wherein the said seed culture medium by weight percentage comprises the following components:soluble starch 1.0-3.5%, KH2PO4 0.1-0.5%, urea 0.1-0.3%, MgSO4 0.05-0.1%, CaCO3 0.1-0.3%, yeast extract powder 0.1-1.0%, corn syrup 0.1-1.0%, (NH4)2SO4 0.1-0.6% and ferulic acid 0.1-0.3%, andwherein fermentation step 3 comprises:the OMK-4 cells from step 2 in exponential growth phase are inoculated into a fermentation medium with the volume ratio of 5-15% under aseptic conditions wherein the initial pH of the fermentation medium is 7.2 to 7.8 at 30-40° C. and 200-500 rpm shaking and 1:0.5 ventilation, to ferment the cells for 70-120 hours, wherein the fermentation medium by weight percentage comprises the following components: soluble starch 2.0-5.0%, KH2PO4 0.1-0.3%, urea 0.1-0.5%, MgSO4 0.05-0.1%, CaCO3 0.5-2.0%, yeast extract powder 0.1-1.0%, (NH4)2SO4 0.1-0.5% and ferulic acid 0.1-3.0%.
US Pat. No. 10,364,455

METHODS AND COMPOSITIONS FOR IMPROVING REMOVAL OF RIBOSOMAL RNA FROM BIOLOGICAL SAMPLES

BIOO Scientific Corporati...

1. A method for removing 28S rRNA from an RNA sample comprising:obtaining an RNA sample from a biological source, said RNA sample containing 28S rRNA;
mixing said RNA sample with one or more RNA subtractive hybridization probes, thereby forming a mixture comprising the RNA sample and the one or more RNA subtractive hybridization probes, wherein the one or more RNA subtractive hybridization probes comprise an affinity label, and wherein the one or more of the RNA subtractive hybridization probes hybridize to two or more discontinuous regions of the 28S rRNA in the RNA sample but do not hybridize to GC rich regions of the 28S rRNA;
incubating the mixture under conditions effective to allow hybridization of the one or more RNA subtractive hybridization probes with the 28S rRNA in the RNA sample, thereby forming a hybridized complex comprising the one or more RNA subtractive hybridization probes and the 28S rRNA;
incubating the hybridized complex with a solid support in a reaction composition containing components that facilitate association of the hybridized complex with the solid support, thereby forming a complex comprising the hybridized complex and the solid support, wherein the affinity label on the one or more RNA subtractive hybridization probes of the hybridized complex specifically binds to an affinity label recognition molecule attached to the solid support; and
removing the 28S rRNA from the RNA sample by removing the complex comprising the hybridized complex and the solid support from the reaction composition.
US Pat. No. 10,364,458

ISOTHERMAL METHODS FOR AMPLIFYING NUCLEIC ACID SAMPLES

Tangen Biosciences, Inc.,...

1. A two-stage nucleic acid amplification and real-time detection method comprising a providing a composition comprising a target nucleic acid template and at least one primer that anneals to the target nucleic acid template near a region of interest to be amplified; b. performing a first nucleic acid amplification reaction to amplify the region of interest, thereby forming a primary amplicon; c. dividing (b) into at least two secondary reactions, and including in at least one of the reactions a site-specific secondary primer that is complementary to a site-specific primer binding site that may be present within the primary amplicon and defines a site of interest within the region of interest; d. performing a second nucleic acid amplification reaction (second-stage reaction) thereby accelerating the amplification of the region of interest only if the site-specific primer binding site is complementary to the site-specific primer; and e. detecting and comparing in real-time the amplification rates of the at least two secondary reactions, wherein an enhanced relative rate of amplification in the reaction with the secondary primer indicates the presence of the site of interest that is complementary to the secondary primer.
US Pat. No. 10,364,459

METHOD OF QUANTITATIVELY AND QUALITATIVELY ANALYZING BIOMATERIAL IN REAL-TIME

SUGENTECH, Inc., Daejeon...

1. A method of quantitatively and qualitatively analyzing a biomaterial in real-time, the method comprising:preparing a device for detecting a biomaterial, wherein the device comprises a reaction container comprising an opening at an upper part thereof; and an element part separately connected to the reaction container via the opening, wherein the element part comprises a cap coupled to the opening of the reaction container; and a rod extended from a lower part of the cap, wherein the rod comprises a biochip having a third probe fixed to a surface of the biochip;
feeding a complex of first and second probes, a forward primer, a reverse primer, a sample comprising deoxynucleotide triphosphate (dNTP), a polymerase having exonuclease activity, and a sample comprising target genes, and a reaction solution comprising a buffer into the reaction container, wherein the first probe comprises oligonucleotide sequences complementary to nucleic acid sequences of the target genes in the sample, a first phosphor for generating a first fluorescence signal, and a first quencher for quenching the first phosphor, the second probe does not comprise oligonucleotide sequences complementary to the nucleic acid sequences of the target genes in the sample, but comprises oligonucleotide sequences complementary to the third probe, and the forward and reverse primers comprise oligonucleotide sequences complementary to the nucleic acid sequences of the target genes to amplify the target genes in the sample;
performing polymerase chain reaction comprising denaturation of the target genes in the sample, hybridization of the target genes, the complex, and the forward and reverse primers in the sample, and elongation of the primers through the polymerase having exonuclease activity, wherein the hybridization is only performed between the target genes and the first probe of the complex, and when the polymerase reaches the complex hybridized with the target genes during the elongation by the polymerase having the exonuclease activity, the second probe and the first phosphor are disassembled and released from the complex hybridized with the target genes by the exonuclease activity of the polymerase, and a first fluorescence signal is generated by the first phosphor;
allowing for DNA microarray in which elongation of the second probe on the third probe by the polymerase after hybridizing the released second probe and the third probe fixed to the biochip are performed, wherein the third probe comprises a second phosphor for generating a second fluorescence signal and a second quencher for quenching the second phosphor, and as the second probe is elongated on the third probe, the secondary structure of the third probe is disassembled, and the second quencher is spaced from the second phosphor, and a second fluorescence signal is generated by the second phosphor; and
detecting a first fluorescence signal by the first phosphor and a second fluorescence signal by the second phosphor.
US Pat. No. 10,364,204

PROCESS FOR MANUFACTURING METHYL TERTIARY-BUTYL ETHER (MTBE) AND OTHER HYDROCARBONS

Lyondell Chemical Techno...

1. A process for manufacturing methyl t-butyl ether (MTBE) comprising:a first step comprising cracking raw material comprising ethane or propane to form ethylene; and recovering residual uncracked raw material;
a second step comprising dimerizing ethylene to form a n-butylene feed stream, wherein the n-butylene feed stream comprises:
(i) about 30 to 50 wt. % of 2-butene, based on the total weight of the feed stream,
(ii) about 25 to 45 wt. % of 1-butene, based on the total weight of the feed stream, and
(iii) a higher molecular weight ethylene oligomer
wherein the dimerizing step is performed at a temperature of about 10-100° C., wherein the dimerizing step takes place in the presence of a dimerization catalyst, wherein the dimerization catalyst comprises a nickel compound and an aluminum compound, and wherein the catalyst has a Ni:Al ratio from 0.9:10 to 1:2.5;
a third step comprising isomerizing the n-butylene feed stream to form an isobutylene stream using a isomerization catalyst at a weight hourly space velocity (WHSV) of 0.2-4 kg feedstock per kg catalyst per hour at a pressure of about 345-3450 kPa and a temperature of about 40-200° C., wherein the isomerization catalyst is an acidic isomerization catalyst;
recovering unconverted n-butylene;
alkylating isobutylene with isobutane at a pressure of at least 600 kPa to form gasoline alkylate;
recovering gasoline alkylate;
isomerizing the higher molecular weight ethylene oligomer; and
recovering the isomerized higher molecular weight ethylene oligomer;
a fourth step comprising oxidizing methane to form methanol;
a fifth step comprising etherifying the isobutylene stream with methanol to form methyl t-butyl ether;
etherifying the higher molecular weight ethylene oligomer contained in the isobutylene stream with methanol to form a higher-molecular-weight-ethylene-oligomer-based methyl ether;
recovering the higher-molecular-weight-ethylene-oligomer-based methyl ether;
etherifying an isomerized higher molecular weight ethylene oligomer contained in the isobutylene stream with methanol to form an isomerized-higher-molecular-weight-ethylene-oligomer-based methyl ether; and
recovering the isomerized-higher-molecular-weight-ethylene-oligomer-based methyl ether; and
a sixth step comprising collecting the methyl t-butyl ether.
US Pat. No. 10,363,203

METHOD OF USE, AND COMPOSITION OF, FIRST RESPONDER WET WIPES

DIAMOND WIPES INTERNATION...

1. A method for decontaminating a skin surface by use of a wet wipe, wherein the wet wipe has a composition consisting essentially of:water, by wt. %, within a range of 90.00 to 98.00;
propanediol, by wt. %, within a range of 0.10 to 5.00;
a first blend, by wt. %, within a range of 0.001 to 1.00;
a second blend, by wt. %, within a range of 0.10 to 5.00;
polysorbate 20, by wt. %, within a range of 0.10 to 5.00;
a third blend, by wt. %, within a range of 0.001 to 1.00;
trisodium phosphate, by wt. %, within a range of 0.001 to 1.00;
citric acid, by wt. %, within a range of 0.001 to 1.00;
caprylyl glycol, by wt. %, within a range of 0.001 to 1.00;
benzalkonium chloride, by wt. %, within a range of 0.001 to 1.00;
phenoxyethanol, by wt. %, within a range of 0.001 to 1.00;
sodium benzoate, by wt. %, within a range of 0.001 to 1.00; and
potassium sorbate, by wt. %, within a range of 0.001 to 1.00;
wherein the first blend consists of the first group consisting essentially of chamomilla recutita (Matricaria) flower extract, cucumis sativus (cucumber) fruit extract, althaea officinalis root extract and avena sativa (oat) kernel extract;
wherein the second blend consists of the second group consisting essentially of decyl glucoside, polyglyceryl-10 caprylate/caprate, coco glucoside, and glyceryl oleata; and
wherein the third blend consists of tetrasodium glutamate diacetate and sodium hydroxide.
US Pat. No. 10,363,204

ZINC OXIDE WHICH IS COATED WITH SILICON OXIDE, METHOD FOR MANUFACTURING THE SAME, COMPOSITION WHICH INCLUDES THE ZINC OXIDE COATED WITH SILICON OXIDE, AND COSMETIC

SUMITOMO OSAKA CEMENT CO....

1. Zinc oxide which is coated with silicon oxide, whereinthe surfaces of zinc oxide particles are coated with silicon oxide coatings,
the silicon oxide coatings include at least one element selected from the group consisting of Mg, Ca, and Ba,
a total mass percentage of the at least one element included in the silicon oxide coating is greater than a mass percentage of an alkali metal included in the silicon oxide coatings; and
a total mass percentage of the at least one element included in the silicon oxide coating is 0.01 to 1% by mass and wherein said at least one element selected from a group consisting of Mg, Ca, and Ba in the silicon oxide coatings is present in a form of magnesium silicate, calcium silicate or barium silicate.
US Pat. No. 10,366,789

METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR NEUROLOGICAL HEALTH ISSUES

uBiome, Inc., San Franci...

1. A method for characterizing a pernicious anemia condition for a subject, the method comprising:for each sample of an aggregate set of samples comprising at least one sample comprising microorganisms associated with the pernicious anemia condition:
determining a microorganism nucleic acid sequence upon fragmenting nucleic acid material from the sample, and amplifying the fragmented nucleic acid material using a primer; and
determining an alignment of the microorganism nucleic acid sequence to a reference nucleic acid sequence, thereby determining alignments;
generating a microbiome feature dataset based on the alignments;
generating a characterization of the pernicious anemia condition based on the microbiome feature dataset;
determining a therapy for the subject based on the characterization and a subject sample from the subject; and
providing the therapy to the subject, wherein the therapy is operable to modulate microbiome composition to improve a state of the pernicious anemia condition.
US Pat. No. 10,364,485

ALUMINUM ALLOY SHEET THAT EXHIBITS EXCELLENT SURFACE QUALITY AFTER ANODIZING AND METHOD FOR PRODUCING THE SAME

UACJ CORPORATION, Chiyod...

1. An aluminum alloy sheet comprising a 5000 series aluminum alloy sheet containing 1.0-6.0 mass % of Mg, the Mg concentration in a solid-solution state that is present in an outermost surface area of the aluminum alloy sheet varying in a widthwise direction of the aluminum alloy sheet in the form of a band having a width of a least 0.05 mm and a difference in the concentration of Mg between adjacent bands is no more than 0.20 mass %, and an oxide coating provided thereon.
US Pat. No. 10,366,793

METHOD AND SYSTEM FOR CHARACTERIZING MICROORGANISM-RELATED CONDITIONS

uBiome, Inc., San Franci...

1. A method for characterizing a human behavior condition associated with microorganisms, the method comprising:collecting samples from a set of subjects, wherein the samples comprise microorganism nucleic acids associated with the human behavior condition;
generating a microorganism sequence dataset for the set of subjects based on the microorganism nucleic acids;
determining at least one of a set of microbiome composition diversity features and a set of microbiome functional diversity features associated with the set of subjects, based on the microorganism sequence dataset;
collecting supplementary data associated with the human behavior condition for the set of subjects;
generating a behavior characterization model based on the supplementary data and the at least one of the set of microbiome composition diversity features and the set of microbiome functional diversity features, wherein the behavior characterization model is associated with the human behavior condition;
generating a human behavior characterization of the human behavior condition for a user based on the behavior characterization model; and
providing a therapy to the user for the human behavior condition based on the human behavior characterization.
US Pat. No. 10,363,721

INTERMEDIATE FILM FOR LAMINATED GLASS AND LAMINATED GLASS

SEKISUI CHEMICAL CO., LTD...

1. An interlayer film for laminated glass comprising:a thermoplastic resin; and
at least one kind of ingredient among a phthalocyanine compound containing copper atom(s) and having a maximum absorption wavelength greater than or equal to 550 nm and less than or equal to 750 nm, a naphthalocyanine compound containing copper atom(s) and having a maximum absorption wavelength greater than or equal to 550 nm and less than or equal to 750 nm, an anthracyanine compound containing copper atom(s) and having a maximum absorption wavelength greater than or equal to 550 nm and less than or equal to 750 nm and an indanthrene compound containing copper atom(s) and having a maximum absorption wavelength greater than or equal to 550 nm and less than or equal to 750 nm,
wherein a content of the at least one kind of ingredient is greater than or equal to 0000001% by weight and less than or equal to 0.05% by weight in 100% by weight of the interlayer film, and
wherein a ratio L?s/Ls of the relative scotopic vision luminance L?s to the relative photopic vision luminance Ls is greater than or equal to 1.0 at the time of preparing laminated glass with two sheets of clear glass in accordance with JIS R3202 (1996).
US Pat. No. 10,363,217

NANO-LIPOSOME CARRIER COMPOSITION CONTAINING HYBRID OF CAS9 PROTEIN AND GUIDE RNA

Moogene Medi Co., Ltd., ...

19. A method for producing a nano-liposome carrier composition, the method comprising:mixing a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated protein 9 (Cas9) protein and a guide RNA that specifically binds to a target DNA of a human dipeptidyl peptidase-4 (DPP4) gene to produce a hybrid CRISPR complex;
mixing a lecithin, a metal chelating lipid, and a cholesterol in chloroform to produce a lipid film composition;
mixing the hybrid CRISPR complex with the lipid film composition to produce a lipid/CRISPR mixture and applying ultrasonic waves to the lipid/CRISPR mixture;
freezing and thawing the lipid/CRISPR mixture;
re-applying ultrasonic waves to the lipid/CRISPR mixture for a time sufficient to form nano-liposomes encapsulating the hybrid CRISPR complex; and
centrifuging the lipid/CRISPR mixture for a time sufficient to precipitate nano-liposomes encapsulating the hybrid CRISPR complex; and
collecting precipitated nano-liposomes encapsulating the hybrid CRISPR complex.
US Pat. No. 10,364,242

MODULATION OF N-ACYLETHANOLAMINE-HYDROLYSING ACID AMIDASE (NAAA) FOR DISEASE TREATMENT

FONDAZIONE ISTITUTO ITALI...

1. The compound (endo)-3-(4-butylphenoxy)-8-[(3,5-dimethyl-1H-pyrazol-4-yl)sulphonyl]-8-azabicyclo[3.2.1]octane, pharmaceutically acceptable salts thereof, its hydrates, solvates and racemic mixtures.
US Pat. No. 10,365,268

METHODS FOR IDENTIFYING MODULATORS OF MEMBRANE POTENTIALS IN BIPOLAR DISORDER AND ATTENTION DEFICIT HYPERACTIVITY DISORDER

PsychNostics, LLC, Ellic...

1. A method of identifying an agent for treatment of attention deficit hyperactivity disorder (ADHD) comprising:combining a first population of human ADHD patient cells comprising cells that express human calcium-activated potassium-channels hSK4, with a test agent suspected of altering human calcium-activated potassium channels hSK4 activity;
obtaining a test ratio of a mean membrane potential of the first population of human ADHD patient cells incubated in vitro in the presence of the test agent suspected of altering human calcium-activated potassium channels hSK4 activity and in the absence of K+, to a mean membrane potential of a second population of the human patient cells incubated in vitro in the absence of the test agent suspected of altering human calcium-activated potassium channels hSK4 activity and presence of K+;
comparing the test ratio to (a) and/or (b):
(a) a control ratio of a mean membrane potential from control human cells known to not have ADHD comprising cells that express human calcium-activated potassium-channels hSK4, incubated in vitro in the presence of a known agent that alters human calcium-activated potassium channels hSK4 activity and in the absence of K+, to a mean membrane potential of the control human cells incubated in vitro in the absence of the known agent that alters human calcium-activated potassium channels hSK4 activity and in the presence of K+,
(b) an ADHD control ratio of a mean membrane potential from ADHD control human cells known to have ADHD comprising cells that express human calcium-activated potassium-channels hSK4, incubated in vitro in the presence of the known agent that alters human calcium-activated potassium channels hSK4 activity and in the absence of K+, to a mean membrane potential of the ADHD control human cells incubated in vitro in the absence of the known agent that alters human calcium-activated potassium channels hSK4 activity and in the presence of K+;
wherein when:
(1) the test ratio is not significantly different from the control ratio of (a),
(2) the test ratio is decreased towards the control ratio of (a) in comparison to the ADHD control ratio of (b), or
(3) the test ratio is decreased in comparison to the ADHD control ratio of (b), the test agent suspected of altering human calcium-activated potassium channels hSK4 activity is identified as the agent for treatment of ADHD and wherein the known agent that alters human calcium-activated potassium channels hSK4 activity is selected from a group consisting of ethanol, amphetamine, ephedrine, cocaine, caffeine, nicotine, methylphenidate, lithium, ?-9-tetrahydrocannibinol, phencyclidine, lysergic acid diethylamide (LSD), mescaline, and combinations thereof.
US Pat. No. 10,363,221

MANUFACTURING SOLID PHARMACEUTICAL DOSAGE FORMS WITH VISIBLE MICRO- AND NANOSTRUCTURED SURFACES AND MICRO- AND NANOSTRUCTURED PHARMACEUTICAL DOSAGE FORM

I-Property Holding Corp.,...

1. A method of forming a pharmaceutical dosage form comprising:impressing, on at least one of a surface and an interface of the dosage form, an area with at least one micro- and/or nanostructure;
the dosage form comprising a quantity and distribution of ingredients so as to enhance an optical contrast effect caused by the impressed micro and/or nanostructure, so that the micro- and/or nanostructure is observable by the human eye,
wherein the impressing is defined by only direct compression of a mixture of selected ingredients with a punching tool to create the solid pharmaceutical dosage form, with the direct compression performed at room temperature without heating and without modifying the physical nature of the material in the mixture, the punching tool having a micro and/or nano-structured surface formed in a tool surface geometry, and wherein particles of the mixture of selected ingredients are sized such that at least some of the particles are reconfigured or deformed by the compressing, these particles thereby taking the shape of the micro and/or nano-structured surface of the punching tool.
US Pat. No. 10,365,272

HIGHLY SENSITIVE IMMUNOASSAY FOR RAPID QUANTIFICATION OF MENINGOCOCCAL CAPSULAR POLYSACCHARIDE ANTIGENS

SERUM INSTITUTE OF INDIA ...

1. A method for quantification of conjugated N. meningitidis serogroup X capsular polysaccharide in a sample using an immunological assay, the method comprising:providing a solid support coated with a capture polyclonal antibody;
providing a sample including N. meningitidis serogroup X capsular polysaccharide-TT conjugate and unconjugated N. meningtitidis serogroup X capsular polysaccharide, wherein the sample is lyophilized and resuspended in phosphate buffer saline having pH 7.2±0.2 comprising KCl at a concentration from 75 mM to 140 mM followed by further dilution or the sample is liquid and directly diluted with phosphate buffer saline having pH 7.2±0.2 comprising KCl at a concentration from 75 mM to 140 mM;
applying the sample to the solid support coated with capture polyclonal antibody;
removing unbound sample;
providing a detection monoclonal antibody;
applying the detection monoclonal antibody to the solid support;
removing unbound detection monoclonal antibody;
applying labeled secondary antibody with a label; and
detecting the label;
wherein the assay does not show any interference due to presence of sucrose and glucose excipients.
US Pat. No. 10,365,275

IMMUNOLOGICALLY ACTIVE POLYPEPTIDE

Institute of Arthritis Re...

1. A method for treating, reducing severity of, or reducing likelihood of occurrence of either or both of TLR2-mediated sepsis and TLR4-mediated sepsis in a subject, comprising administering to the subject a therapeutically effective amount of an immunomodulatory polypeptide of no more than 31, 30, 29, 28, 27, 26, 25, 24, 23, 22, 21, 20, 19, 18, 17, 16, 15, 14, 13 or 12 amino acids that comprises the amino acid sequence KSIAYLQMNSLK as set forth in SEQ ID NO:2.
US Pat. No. 10,365,277

METHOD FOR MEASURING HEMAGGLUTININ FROM INFLUENZA VIRUS

DENKA SEIKEN CO., LTD., ...

1. A method for measuring haemagglutinin of an influenza virus by a sandwich immunoassay method, said method comprising:extracting haemagglutinin from a sample containing the influenza virus by adding a cationic or anionic surfactant;
combining the extracted haemagglutinin with at least one lectin immobilized on a solid support and with a labeled anti-haemagglutinin antibody that undergoes antigen-antibody reaction with the haemagglutinin; and
measuring the haemagglutinin by sandwich immunoassay, wherein detection of the presence of haemagglutinin indicates the presence of influenza virus,
wherein the at least one lectin binds the haemagglutinin, but does not bind the anti-haemagglutinin antibody, and wherein the at least one lectin is Datura stramonium lectin, and
wherein the cationic and anionic surfactant is at least one selected from the group consisting of sodium dodecyl sulfate, lithium dodecyl sulfate, hexadecyltrimethylammonium bromide, hecadecyltrimethylammonium chloride and hexadecylpyridinium chloride.
US Pat. No. 10,363,232

COMPOSITIONS AND METHODS FOR TREATING SEVERE PAIN

Infirst Healthcare Limite...

1. A method of treating an individual with an inflammatory pain, the method comprising the step of: administering to the individual in need thereof a pharmaceutical composition, wherein the pharmaceutical composition comprises:a) a propionic acid derivative non-steroidal anti-pain drug (NSAID), or a pharmaceutically acceptable salt, solvate, or solvate of a salt thereof, in an amount of about 15% to about 30% of the total weight of the composition; and
b) a pharmaceutically-acceptable lipid in an amount of at least 50% of the total weight of the composition, the pharmaceutically-acceptable lipid comprising a pharmaceutically-acceptable triglyceride in an amount of at least 30% of the total weight of the composition, and a pharmaceutically-acceptable glyceride mixture including a monoglyceride, the pharmaceutically-acceptable glyceride mixture in an amount of at least 20% of the total weight of the composition,
wherein the pharmaceutical composition is formulated to be a solid at a temperature of about 15° C. or lower and have a melting point temperature of about 25° C. or higher.
US Pat. No. 10,363,233

GRANULAR FEED SUPPLEMENT

14. A method of supplementing the diet of a ruminant with lysine, the method comprising:providing the ruminant with a ruminant feed composition comprising:
a granulated core comprising lysine sulfate; and
a coating material of two or more layers surrounding the core, the coating material comprising;
oleic acid,
stearic acid, and
palmitic acid;
wherein the total amount of stearic and palmitic acids is at least 90 wt % of the total weight of the coating,
wherein the lysine exhibits a rumen bypass rate greater than 75%, and an intestinal digestibility rate greater than 70%, and
wherein the weight % ratio of core material to coating material is from 50:50 to 70:30.
US Pat. No. 10,364,515

HIGH MODULUS NYLON 6.6 CORDS

KORDSA TEKNIK TEKSTIL ANO...

1. A two or three-ply dipped and heat-set polyamide 6.6 cord comprising: a plurality of polyamide 6.6 raw yarns;wherein the plurality of polyamide 6.6 raw yarns have a tensile stress value greater than 1.30 cN/dtex;
wherein a stress value at 4% elongation of the polyamide 6.6 cord is higher than 1.2 cN/dtex and less than 2.0 cN/dtex,
wherein a heat shrinkage of the polyamide 6.6 cord is higher than 4.0% and less than 7.0% determined at 177° C. under 0.045 g/dtex pretension with 2 minutes exposure time;
wherein the tensile stress value is determined with a tensile tester according to ASTM D885-16.
US Pat. No. 10,364,265

ANHYDROSUGAR SYNTHESIS

William Marsh Rice Univer...

1. A method of making an anhydrosugar, comprising:a) dissolving a carbohydrate substrate in a solvent;
b) performing a Fischer glycosidation on the C1 carbon of said carbohydrate substrate by reacting said dissolved sugar substrate with an alcohol in the presence of a solid acid catalyst, wherein said Fischer glycosidation adds the alcohol on said C1 carbon as an ether;
c) removing said solid acid catalyst and said solvent to form a solid sample; and,
d) performing heat treatment on said solid sample to produce a desired anhydrosugar.
US Pat. No. 10,364,273

CYTOMEGALOVIRUS ANTIGENS

GLAXOSMITHKLINE BIOLOGICA...

1. A recombinant cytomegalovirus (CMV) gB protein, or an immunogenic fragment thereof, wherein(i) said gB protein, or immunogenic fragment thereof, does not comprise a transmembrane (TM) domain;
(ii) said gB protein, or immunogenic fragment thereof, comprises a hydrophobic surface 1 that corresponds to amino acid residues 154-160 and 236-243 of SEQ ID NO: 1 which comprises a mutation that results in a glycosylation site within said hydrophobic surface 1, but wherein the mutation is not a substitution of one amino acid in fusion loop 1 (FL1) which corresponds to amino acid residues 155-157 of SEQ ID NO: 1.
US Pat. No. 10,364,274

EXPRESSION OF CHIMERIC KSAC PROTEIN AND METHOD OF PRODUCING SOLUBLE PROTEINS BY HIGH PRESSURE

BOEHRINGER INGELHEIM ANIM...

1. A composition comprising (i) a refolded and solubilized fusion protein and (ii) dithiothreitol (DTT), wherein the fusion protein consists of leishmania antigens Kinetoplastid Membrane Protein 11 (KMP11), Sterol MethylTransferase (SMT), A2 and Cysteine Proteinase (CP), and wherein the fusion protein comprises the sequence as set forth in SEQ ID NO:2.
US Pat. No. 10,365,555

MASK BLANK, TRANSFER MASK AND METHODS OF MANUFACTURING THE SAME

HOYA CORPORATION, Tokyo ...

1. A mask blank comprising a light-semitransmissive film and a light-shielding film on a main surface of a transparent substrate, wherein:the light-semitransmissive film is made of a material that is capable of being dry-etched with an etching gas containing a fluorine-based gas,
the light-shielding film, except for a surface layer thereof, is made of a material that consists of tantalum, one or more elements selected from hafnium and zirconium, and one or more elements selected from nitrogen, carbon, hydrogen, boron and inert gases,
the surface layer of the light-shielding film is made of a material that consists of tantalum, oxygen, one or more elements selected from hafnium and zirconium, and one or more elements selected from nitrogen, carbon, hydrogen, boron and inert gases,
a ratio, given in percent, obtained by dividing the total content [at %] of hafnium and zirconium in the light-shielding film by the total content [at %] of tantalum, hafnium and zirconium in the light-shielding film is 10% or more and 50% or less,
an etching stopper film is provided between the light-semitransmissive film and the light-shielding film, and
the etching stopper film is made of a material that contains chromium and has an oxygen content of 20 at % or less.
US Pat. No. 10,365,556

MASK BLANK, PHASE SHIFT MASK, METHOD FOR MANUFACTURING PHASE SHIFT MASK, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE

HOYA CORPORATION, Shinju...

1. A mask blank, comprising a phase shift film on a transparent substrate,the phase shift film having a function of transmitting exposure light of an ArF excimer laser with a transmittance of 2% or more, and a function of generating a phase difference of 150 degrees or more between the exposure light that has been transmitted through the phase shift film and the exposure light that has passed through air by a distance that is the same as a thickness of the phase shift film,
the phase shift film having a structure in which a silicon layer and a phase shift layer are laminated in the stated order from the substrate side,
the phase shift layer being formed, except for a surface layer portion thereof, of a material made of silicon and nitrogen, or a material containing, in addition to the material made of silicon and nitrogen, one or more elements selected from non-metallic elements other than oxygen, and metalloid elements,
the phase shift layer having a thickness that is larger than that of the silicon layer,
wherein the silicon layer has a thickness of 3 nm or more and less than 12 nm.
US Pat. No. 10,364,276

PEPTIDE FOR INDUCING REGENERATION OF TISSUE AND USE THEREOF

STEMRIM INC., Osaka (JP)...

1. A method of stimulating migration of a cell, mobilizing a cell from bone marrow to peripheral blood, and/or regenerating a tissue, in the body of a subject, wherein said method comprises administering to the subject an effective amount of a substance of any one of (a) to (c) below;(a) a peptide consisting of a portion of an HMGB1 protein of SEQ ID NO:1 and having cell migration-stimulating activity;
(b) a cell secreting said peptide of (a); and
(c) a vector into which a DNA encoding said peptide of (a) is inserted, wherein said peptide has an activity of stimulating migration of a cell and said peptide consists of all or part of the amino acid sequence of positions 1 to 195 of SEQ ID NO:1.
US Pat. No. 10,363,255

STABLE AND SOLUBLE FORMULATIONS OF RECEPTOR TYROSINE KINASE INHIBITORS, AND METHODS OF PREPARATION THEREOF

FORSIGHT VISION4, INC., ...

1. A pharmaceutical solution comprising:(i) ?-cyclodextrin sulfobutyl ether, hydroxypropyl ?-cyclodextrin, or a combination thereof;
(ii) about 0.2% to about 1.0% of polyvinylpyrrolidone; and
(iii) about 30 mg/mL to about 60 mg/mL of an ophthalmic therapeutic agent having a solubility of less than 1 mg/mL in water;wherein the weight ratio of (i) to (iii) is from about 2:1 to about 8:1.
US Pat. No. 10,364,535

VOID REDUCING ASPHALT MEMBRANE COMPOSITION, METHOD AND APPARATUS FOR ASPHALT PAVING APPLICATIONS

Heritage Research Group, ...

1. A method of forming a pavement construction joint, comprising:dispensing a band of a void reducing joint composition on a substrate using at least one spray application vehicle, wherein the band comprises a width of about 4 to about 24 inches and a sufficient thickness to permit migration upward into a paving pass positioned over the band to reduce an air void volume in such paving pass;
permitting the application of two paving passes to form a pavement construction joint having a volume of air voids, wherein the pavement construction joint is positioned over the band; and
allowing at least a portion of the joint composition to migrate upward into the two paving passes along the pavement construction joint to reduce the volume of air voids.
US Pat. No. 10,363,262

COMPOSITION FOR TREATING WOUND COMPRISING GYPENOSIDE LXXV

INTELLIGENT SYNTHETIC BIO...

1. A method of wound healing or skin regeneration, comprising administering a composition comprising gypenoside 75 (gypenoside LXXV).
US Pat. No. 10,363,263

ANTI-AGING COMPOSITIONS AND METHODS FOR USING SAME

Prescient Pharma, LLC, C...

1. A pharmaceutical composition comprising an effective amount of at least one lithium compound selected from lithium chloride, lithium bromide, lithium carbonate, lithium nitrate, lithium sulfate, lithium acetate, lithium lactate, lithium citrate, lithium aspartate, lithium gluconate, lithium malate, lithium ascorbate, lithium orotate, lithium succinate, and combinations thereof; an effective amount of at least one glycyrrhizic triterpenoid compound selected from glycyrrhizin, enoxolone, carbenoxolone, cicloxolone, and combinations thereof, or a pharmaceutically acceptable salt thereof; andan effective amount of at least one retinoic acid compound or a pharmaceutically acceptable salt thereof;
wherein the composition is formulated for oral administration.
US Pat. No. 10,364,289

ANTIBODY BINDING TO NEUROPILIN 1 AND USE THEREOF

SAMSUNG LIFE PUBLIC WELFA...

1. An antibody or an antigen-binding fragment thereof that binds to NRP1, comprising:a heavy chain variable region comprising CDRH1, CDRH2, and CDRH3, respectively, comprising sequences of SEQ ID NOS: 1 to 3 and a light chain variable region comprising CDRL1, CDRL2, and CDRL3, respectively, comprising sequences of SEQ ID NO: 4, ANN, and SEQ ID NO: 6;
a heavy chain variable region comprising CDRH1, CDRH2, and CDRH3, respectively, comprising sequences of SEQ ID NOS: 7 to 9 and a light chain variable region comprising CDRL1, CDRL2, and CDRL3, respectively, comprising sequences of SEQ ID NO: 10, SDN, and SEQ ID NO: 12; or
a heavy chain variable region comprising CDRH1, CDRH2, and CDRH3, respectively, comprising sequences of SEQ ID NOS: 7, 8, and 13 and a light chain variable region comprising CDRL1, CDRL2, and CDRL3, respectively, comprising sequences of SEQ ID NO: 10, SDS, and SEQ ID NO: 15.
US Pat. No. 10,363,524

PROCESS FOR REMOVING OXYGEN FROM A GAS MIXTURE COMPRISING HYDROCARBON AND OXYGEN

WACKER CHEMIE AG, Munich...

1. A process for removing oxygen from a recycle gas mixture containing hydrocarbon and oxygen from the preparation of vinyl acetate monomer, the process comprising:separating vinyl acetate and acetic acid from the recycle gas mixture, forming a partially purified recycle gas, contacting the partially purified recycle gas with a coated catalyst to remove oxygen to form an oxygen-depleted recycle gas containing carbon dioxide and water, freeing the oxygen-depleted recycle gas of carbon dioxide, removing water from the oxygen-depleted recycle gas now freed of carbon dioxide, and condensing ethylene by means of fractional low-temperature condensation to form an ethylene recycle stream wherein the coated catalyst comprises bentonite-containing catalyst supports, configured as shaped bodies, having an outer shell comprising the metals
a) gold, and
b) one or more metals selected from the group consisting of palladium, platinum, rhodium, and iridium,
wherein the metals are present in metallic form, as an alloy, in the form of salts, or mixtures thereof, wherein the outer shell does not contain any alkali metals or alkali metal salts.
US Pat. No. 10,363,271

COMPOSITIONS FOR BIOLOGICAL SYSTEMS AND METHODS FOR PREPARING AND USING THE SAME

SMART Surgical, Inc., Bo...

1. A method of making a composition for influencing biological growth configured for implantation within a subject, the method comprising:(A) obtaining a sample comprising human umbilical cord blood and having a first volume VUC, wherein the human umbilical cord blood includes red blood cells, cells other than red blood cells, and non-cellular material;
(B) combining the sample comprising human umbilical cord blood with a quantity of an aggregation agent or sedimentation agent having a volume VPC, wherein the ratio VUC/VPC is between about 0.60 and about 1.75 such that a supernatant is formed;
(C) layering within a container at least a portion of the supernatant over a layer of an isolation reagent, the at least a portion of the supernatant having a volume VS and the layer of the isolation reagent having a volume VR, wherein the volume of the layer of the isolation reagent VR is at least 67% the volume VS of the at least a portion of the supernatant;
(D) placing at least about 350 times the acceleration due to gravity on the contents of the container with a force vector directed toward a closed end of the container to safely cause at least a new layer substantially comprising mononuclear cells to form;
(E) combining at least some of the layer substantially comprising mononuclear cells with lactated Ringer's solution or an equivalent balanced or buffered solution to create a mononuclear cell solution;
(F) determining the total number of live cells NL in at least a portion of the mononuclear cell solution, the at least a portion of the mononuclear solution having a volume VM; and
(G) adding a volume VDD of Low Molecular Weight Dextran in Dextrose solution to the at least a portion of the mononuclear cell solution, the volume VDD based at least in part on the total number NL of live cells and the anticipated future viability of the live cells.
US Pat. No. 10,364,295

RECOMBINANT MONOCLONAL ANTIBODIES AND CORRESPONDING ANTIGENS FOR COLON AND PANCREATIC CANCERS

PRECISION BIOLOGICS, INC....

1. An isolated nucleic acid encoding at least one of the light or heavy chain of an a monoclonal antibody or antigen-binding fragment thereof that binds to the human colorectal and pancreatic carcinoma-associated antigen (CPAA) expressed by LS174T colorectal cancer cells and bound by the NPC-1 antibody consisting of the light chain variable region of SEQ ID NO: 1 and the heavy chain variable region of SEQ ID NO: 4, wherein said monoclonal antibody or antigen-binding fragment thereof comprises the light chain CDR1 amino acid sequence of SEQ ID NO:7, light chain CDR2 amino acid sequence of SEQ ID NO:8, and light chain CDR3 amino acid sequence of SEQ ID NO:9, and wherein said monoclonal antibody or antigen-binding region thereof comprises the heavy chain CDR1 amino acid sequence of SEQ ID NO:10, heavy chain CDR2 amino acid sequence of SEQ ID NO:11, and heavy chain CDR3 amino acid sequence of SEQ ID NO:12.
US Pat. No. 10,364,296

ANTIBODIES SPECIFIC FOR MMP9

CALYPSO BIOTECH SA, Plan...

1. An isolated antibody specific for MMP9 or an antigen-binding fragment thereof, said antibody or antigen-binding fragment comprising:a) a heavy chain variable region comprising:
(i) SEQ ID NO: 2 (heavy chain CDR1) or a variant thereof wherein 1, 2, or 3 amino acids of said heavy chain CDR1 is substituted by a different amino acid;
(ii) SEQ ID NO: 3 (heavy chain CDR2) or a variant thereof wherein 1, 2, or 3 amino acids of said heavy chain CDR2 is substituted by a different amino acid; and
(iii) SEQ ID NO: 4 (heavy chain CDR3) or a variant thereof wherein 1, 2, or 3 amino acids of said heavy chain CDR3 is substituted by a different amino acid; and
b) a light chain variable region comprising:
(i) SEQ ID NO: 21 (light chain CDR1) or a variant thereof wherein 1, 2, or 3 amino acids of said light chain CDR1 is substituted by a different amino acid;
(ii) SEQ ID NO: 22 (light chain CDR2) or a variant thereof wherein 1, 2, or 3 amino acids of said light chain CDR2 is substituted by a different amino acid; and
(iii) SEQ ID NO: 23 (light chain CDR3) or a variant thereof wherein 1, 2, or 3 amino acids of said light chain CDR3 is substituted by a different amino acid, or
c) a light chain variable region comprising:
(i) SEQ ID NO: 26 (light chain CDR1) or a variant thereof wherein 1, 2, or 3 amino acids of said light chain CDR1 is substituted by a different amino acid;
(ii) SEQ ID NO: 27 (light chain CDR2) or a variant thereof wherein 1, 2, or 3 amino acids of said light chain CDR2 is substituted by a different amino acid; and
(iii) SEQ ID NO: 28 (light chain CDR3) or a variant thereof wherein 1, 2, or 3 amino acids of said light chain CDR3 is substituted by a different amino acid.
US Pat. No. 10,363,273

PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY

IOVANCE BIOTHERAPEUTICS, ...

1. A method for treating a subject with head and neck cancer, the method comprising administering expanded tumor infiltrating lymphocytes (TILs) comprising:(a) obtaining a first population of TILs from a tumor resected from a subject by processing a tumor sample obtained from the subject into multiple tumor fragments;
(b) adding the tumor fragments into a closed system;
(c) performing a first expansion by culturing the first population of TILs in a cell culture medium comprising IL-2 to produce a second population of TILs, wherein the first expansion is performed in a closed container providing a first gas-permeable surface area, wherein the first expansion is performed for about 3-11 days to obtain the second population of TILs, wherein the second population of TILs is at least 50-fold greater in number than the first population of TILs, and wherein the transition from step (b) to step (c) occurs without opening the system;
(d) performing a second expansion by supplementing the cell culture medium of the second population of TILs with additional IL-2, OKT-3, and antigen presenting cells (APCs), to produce a third population of TILs, wherein the second expansion is performed for about 7-11 days to obtain the third population of TILs, wherein the second expansion is performed in a closed container providing a second gas-permeable surface area, and wherein the transition from step (c) to step (d) occurs without opening the system;
(e) harvesting the third population of TILs obtained from step (d), wherein the transition from step (d) to step (e) occurs without opening the system;
(f) transferring the harvested third TIL population from step (e) to an infusion bag, wherein the transfer from step (e) to (f) occurs without opening the system;
(g) cryopreserving the infusion bag comprising the harvested TIL population from step (f) using a cryopreservation process; and
(h) administering a therapeutically effective dosage of the third population of TILs from the infusion bag in step (g) to the subject.
US Pat. No. 10,363,274

RENAL CELL POPULATIONS AND USES THEREOF

INREGEN, Grand Cayman (K...

1. A method of identifying a heterogeneous renal cell population, said method comprising the steps:isolating cells from a mammalian kidney sample;
exposing said isolated cells to labeled detection moieties for biomarkers, wherein each labeled detection moiety is directed to a different biomarker and is labeled, wherein the biomarkers comprise GGT-1 and a cytokeratin;
determining the percentage of cells that express each of said different biomarker; and
determining whether the cell population comprises cells that express VEGF and KIM-1.
US Pat. No. 10,364,304

METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER

TOHO TITANIUM CO., LTD., ...

1. A method for producing a solid catalyst component, the method comprising:contacting a magnesium compound, a first tetravalent titanium halide compound, and an electron donor compound represented by formula (1) with each other:
(R1)kC6H4-k(COOR2)(COOR3)  (1);
reacting the magnesium compound, the first tetravalent titanium halide compound, and the electron donor compound represented by formula (1) to obtain a first reaction product;
washing the first reaction product to obtain a solid component;
contacting the solid component, a second tetravalent titanium halide compound, and one or more compound (2) selected from dimethyl isopropylbromomalonate, dimethyl butylbromomalonate, dimethyl isobutylbromomalonate, dimethyl isopropylmalonate, dimethyl butylmalonate, dimethyl isobutylmalonate, dimethyl isopentylmalonate, dimethyl diisopropylmalonate, dimethyl dibutylmalonate, dimethyl diisobutylmalonate, dimethyl diisopentylmalonate, dimethyl isopropylisobutylmalonate, dimethyl bis(3-chloro-n-propyl)malonate or dimethyl bis(3-bromo-n-propyl)malonate
reacting the solid component, the second tetravalent titanium halide compound, and said one or more compound (2) to obtain a second reaction product; and
washing the second reaction product, to obtain a solid catalyst component,
wherein:
R1 represents an alkyl group having 1 to 8 carbon atoms or a halogen atom;
R2 and R3 independently represent an alkyl group having 1 to 12 carbon atoms, wherein R2 and R3 are either identical or different;
k represents 0, 1, or 2, wherein R1 are either identical or different when k is 2;
wherein the electron donor compound represented by formula (1) and said one or more compound (2) are not contacted with each other in the preparation of the solid component and the solid catalyst component.
US Pat. No. 10,363,538

SUBSTRATE FOR BIOCHIPS AND METHOD FOR PRODUCING SAME

NIPPON LIGHT METAL COMPAN...

1. A substrate for biochips, comprising a surface which comprises carbon; and an acrylic polymer which comprises free carboxyl groups in a molecular structure thereof,wherein the carbon is amorphous carbon,
wherein the acrylic polymer is immobilized directly on said surface of said substrate,
wherein the acrylic polymer is selected from the group consisting of polyacrylic acid, polymethacrylic acid and a copolymer of acrylic acid and methacrylic acid, and
wherein the acrylic polymer has an average molecular weight of 2,000 to 100,000.
US Pat. No. 10,363,285

METHODS AND COMPOSITIONS FOR STIMULATION OF CELL PROLIFERATION AND PROVISION OF BIOLOGICALLY ACTIVE MIXTURES OF FGF2 ISOFORMS

SanBio, Inc., Mountain V...

1. A method for providing a mixture of cytoplasmic fibroblast growth factor-2 (FGF-2) isoforms to a cell, tissue or subject, the method comprising:contacting the cell, tissue or subject with a preparation obtained from descendants of mesenchymal stem cells (MSCs) that have been transiently transfected with a vector comprising sequences encoding a Notch intracellular domain (NICD), wherein the preparation is selected from one or both of a soluble cell-free extract and an insoluble cell residue.
US Pat. No. 10,364,309

SUPPORTED POLYMERISATION CATALYSTS

INEOS SALES (UK) LIMITED,...

1. A method for the preparation of a supported polymerisation catalyst system comprising the following steps:(a) pretreating a porous support with (i) a chemical dehydration agent and (ii) a hydroxy compound to form a pretreated support,
(b) adding a cocatalyst to the pretreated support, and
(c) adding a metallocene polymerisation catalyst to the pretreated support, and
adding a polymerisable monomer to the cocatalyst prior to adding the metallocene polymerization catalyst or concurrently with adding the metallocene polymerization catalyst.
US Pat. No. 10,363,287

METHOD OF MANUFACTURING AN OSMOTIC DELIVERY DEVICE

INTARCIA THERAPEUTICS, IN...

1. A method of manufacturing an osmotic delivery device comprising loading a suspension formulation into a reservoir of the osmotic delivery device,the suspension formulation comprising:
a particle formulation comprising
an insulinotropic peptide, an antioxidant, and a buffer, wherein the insulinotropic peptide is at least one of exenatide, a derivative of exenatide, and an analogue of exenatide; and
a non-aqueous, single-phase suspension vehicle that comprises about 20 wt % to about 60 wt % solvent and about 80 wt % to about 40 wt % pyrrolidone polymer, the suspension vehicle having a viscosity from 5,000 poise to 50,000 poise at 33° C.;
wherein:
the solvent is at least one of lauryl lactate, lauryl alcohol, and benzyl benzoate;
30 to 90% by weight of the particle formulation is the insulinotropic peptide; the particle formulation has a wt % ratio of insulinotropic peptide to antioxidant of 2.5/1 to 10/1; and the particle formulation is dispersed in the suspension vehicle.
US Pat. No. 10,363,288

INSULIN MIMOTOPES AND METHODS OF USING THE SAME

National Jewish Health, ...

1. A method for assessing the efficacy of a therapeutic or preventative therapy in a human subject with T1D, or suspected of having T1D, or at risk of developing T1D, comprising:contacting peripheral blood mononuclear cells (PBMC) from a first biological sample from a subject with a peptide comprising the amino acid sequence of SEQ ID NO:2 and detecting IFN-gamma and IL10 cytokine production by the PBMC by enzyme-linked immunospot (ELISPOT) assay;
contacting PBMC from a second biological sample taken from the subject after a period of treatment with the therapy, with a peptide comprising the amino acid sequence of SEQ ID NO:2 and detecting IFN-gamma and IL10 cytokine production by the PBMC by enzyme-linked immunospot (ELISPOT) assay;
assessing the therapy as effective when IFN-gamma cytokine production in the second sample is less than the IFN-gamma cytokine production in the first sample; and,
assessing the therapy as effective when IL10 cytokine production in the second sample is greater than the IFN-gamma cytokine production in the first sample.
US Pat. No. 10,363,544

PARTICULATE WATER-ABSORBING AGENT

NIPPON SHOKUBAI CO., LTD....

1. A particulate water-absorbing agent comprising a water-absorbing resin as a main component, and further including a water-insoluble metal phosphate including an anion of a phosphoric acid compound and a divalent or trivalent metal cation, the water-insoluble metal phosphate having a crystallite size of less than 0.15 ?m,wherein a proportion of particles included in a range of 150 ?m to 850 ?m is 95% by mass or more, particles having a size of 850 ?m or more is 0% to 5% by mass, and a proportion of the fine particles having a particle size of less than 150 ?m is 0% to 3% by mass,
the particulate water-absorbing agent has a fluid retention capacity under pressure of 2.06 kPa of 20 g/g or more, and
a moisture absorption blocking ratio after standing 1 hour at a temperature of 25° C. and a relative humidity of 90±5% RH is 30% by mass or less.
US Pat. No. 10,363,546

MULTILAYER POLYMERIC MEMBRANE

Liso Plastics LLC, Charl...

1. A multilayer sorbent polymeric membrane comprising at least one layer comprising: a matrix polymer, sorbent materials of about 100 wt. % or less, and a plurality of interconnecting pores having an average pore size of about 0.1 nm or greater,wherein the matrix polymer is a film-forming thermoplastic polymer selected from the group consisting of petroleum-based polymers, bio-based polymers, biodegradable polymers, and combinations thereof;
wherein the sorbent materials present in the membrane retain their initial sorbability and/or their initial porosity of about 100% or less; and
wherein the membrane has a porosity of about 85% or less and a Gurley air permeability of about 1 sec/100 cc or greater.
US Pat. No. 10,363,291

METHODS FOR INTRODUCING MANNOSE 6-PHOSPHATE AND OTHER OLIGOSACCHARIDES ONTO GLYCOPROTEINS AND APPLICATIONS THEREOF

Genzyme Corporation, Cam...

1. A method of coupling a beta-glucuronidase to an oligosaccharide comprising a phosphorylated mannose, comprising:(a) derivatizing an oligosaccharide comprising a phosphorylated mannose with a compound containing a carbonyl-reactive group;
(b) oxidizing a beta-glucuronidase having at least one oligosaccharide to generate at least one carbonyl group on the at least one oligosaccharide of the beta-glucuronidase, wherein less than or equal to about 10 mM periodate is used to oxidize one or more sialic acid residues on the beta-glucuronidase; and
(c) reacting the derivatized oligosaccharide with the oxidized beta-glucuronidase,
thereby coupling the oligosaccharide to the beta-glucuronidase.
US Pat. No. 10,362,781

METHODS OF CONTROLLING THE BREEDING BEHAVIOR OF BUTTERFLIES

University of the West In...

14. A method of controlling the population size of a citrus-feeding swallowtail butterfly (Heraclides andraemon) species which naturally feeds on a plant of interest, comprising:(a) providing a host plant in a pretreatment state and selecting a chemical attractant extracted from the plant of interest which naturally attract the citrus-feeding swallowtail butterfly (Heraclides andraemon) species;
(b) applying to the host plant the chemical attractant to attract the citrus-feeding swallowtail butterfly (Heraclides andraemon) species to the host plant and to cause the citrus-feeding swallowtail butterfly (Heraclides andraemon) species to lay eggs on the host plant; and
(c) applying to the host plant or directly to the citrus-feeding swallowtail butterfly (Heraclides andraemon) species or the laid eggs an extract from Piper plant that contains a toxin that kills the citrus-feeding swallowtail butterfly (Heraclides andraemon) species,
wherein a majority of the citrus-feeding swallowtail butterfly (Heraclides andraemon) species or the laid eggs die from ingesting or coming into contact with the extract.
US Pat. No. 10,362,782

METHOD FOR CONTROLLING RUST

UPL Limited, Haldia, Wes...

1. A fungicidal combination, consisting of:(i) mancozeb,
(ii) prothioconazole, and
(a) at least one succinate dehydrogenase inhibitor fungicide selected from the group consisting of benodanil, flutolanil, mepronil, fluopyram, fenfuram, carboxin, oxycarboxin, thifluzamide, bixafen, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad, sedaxane, and boscalid; or
(b) at least one quinone outside inhibitor fungicides selected from the group consisting of fenamidone, famoxadone, and a strobilurin fungicide selected from the group consisting of azoxystrobin, mandestrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, pyraoxystrobin, dimoxystrobin, enestrobin, fluoxastrobin, kresoxim-methyl, metominostrobin, orysastrobin, picoxystrobin, pyrametostrobin, triclopyricarb, fenaminstrobin, pyraclostrobin and trifloxystrobin; or
(c) at least one demethylation inhibitor fungicide selected from the group consisting of triflumizole, triforine, pyridinitrile, pyrifenox, fenarimol, nuarimol, triarimol, and a conazole fungicide selected from the group consisting of climbazole, clotrimazole, imazalil, oxpoconazole, prochloraz, prochloraz-manganese, triflumizole, azaconazole, bitertanol, bromuconazole, cyproconazole, diclobutrazol, difenoconazole, diniconazole, diniconazole-M, epoxiconazole, etaconazole, fenbuconazole, fluotrimazole, fluquinconazole, flusilazole, flutriafol, furconazole, imibenconazole, ipconazole, furconazole-cis, metconazole, hexaconazole, myclobutanil, pencoconazole, propiconazole, prothioconazole, quinconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, uniconazole, perfurazoate, and uniconazole-P; and
(iii) at least one agriculturally acceptable excipient.
US Pat. No. 10,363,294

YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS

GlobeImmune, Inc., Louis...

1. A method to treat cancer in an individual, comprising administering to an individual who has cancer, an immunotherapeutic composition comprising:a) a whole, inactivated yeast; and
b) a cancer antigen comprising a Brachyury antigen, wherein the Brachyury antigen comprises SEQ ID NO:6, positions 2-435 of SEQ ID NO:6, SEQ ID NO:18, or positions 2-435 of SEQ ID NO:18.
US Pat. No. 10,363,295

PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST NHL AND OTHER CANCERS

IMMATICS BIOTECHNOLOGIES ...

1. A method of eliciting an immune response in a HLA-A*02+ patient who has cancer, comprising administering to the patient a population of activated antigen-specific CD8+ cytotoxic T cells that kill cancer cells that present at their surface a peptide consisting of the amino acid sequence of KLLNLISKL (SEQ ID NO: 274) in a complex with an MHC class I molecule,wherein the activated antigen-specific CD8+ cytotoxic cells are produced by a method comprising contacting in vitro CD8+ cytotoxic T cells with an antigen presenting cell presenting at its surface a peptide consisting of KLLNLISKL (SEQ ID NO: 274) in a complex with an MHC class I molecule, and
wherein said cancer is selected from the group consisting of non-Hodgkin lymphomas, chronic lymphocytic leukemia, uterine cancer, lung cancer, kidney cancer, brain cancer, stomach cancer, colon or rectal cancer, liver cancer, prostate cancer, acute myelogenous leukemia, breast cancer, Merkel cell carcinoma (MCC), melanoma, ovarian cancer, esophageal cancer, urinary bladder cancer, endometrial cancer, gall bladder cancer, and bile duct cancer.
US Pat. No. 10,363,296

PEPTIDES AND COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN IMMUNOTHERAPY AGAINST RENAL CELL CARCINOMA (RCC) AND OTHER CANCERS

IMMATICS BIOTECHNOLOGIES ...

1. A method of eliciting an immune response in a patient who has cancer, comprising administering to said patient a population of activated T cells that selectively recognize cancer cells that aberrantly present a peptide consisting of the amino acid sequence of TLMPNINKL (SEQ ID NO: 150),wherein said cancer is selected from the group consisting of brain cancer, stomach cancer, liver cancer, leukemias, melanoma, and esophageal cancer.
US Pat. No. 10,362,785

ACTIVATED HYDROGEN PEROXIDE BIOCIDE COMPOSITION

99 HOLDING S.A.R.L., Lux...

1. An aqueous composition consisting essentially of:0.1-1 g/kg Di-n-decyldimethyl ammonium chloride,
0.01-0.10 g/kg benzalkonium chloride,
50-79 g/kg stabilized H2O2,
0.02-0.10 g/kg hydroxyethylidene diphosphonic acid,
0.2-0.6 g/kg C10ethoxylated alcohol having a degree of ethoxylation of 6 mol,
0.01-0.02 g/kg sorbitan monolaurate having a degree of ethoxylation of 20 mol,
up to 1 kg deionized or purified water, and
a sufficient amount of phosphoric acid to reach a pH between 2-3;
wherein the aqueous composition is in the form of a dry mist made up of microdroplets having an average size of less than 5 ?m.
US Pat. No. 10,363,297

IMMUNOGENIC COMPOSITIONS CONTAINING ESCHERICHIA COLI H7 FLAGELLA AND METHODS OF USE THEREOF

The University Court of t...

1. A method for generating a mucosal and/or IgA response in a subject in need thereof, said method comprising the parenteral administration of Escherichia coli H7 or a Toll-like receptor 5 (TLR5) activating fragment thereof.
US Pat. No. 10,363,298

IMMUNOMODULATORY COMPOUNDS

University Court of the U...

1. A method of modulating or priming an immune response in a subject, the method comprising administering an immunomodulatory amount or quantity of Sp2CBMTD to a healthy subject in need thereof in more than one dose prior to an infection or a likely infection caused or contributed to by a pathogen.
US Pat. No. 10,363,299

COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING RHINOVIRUS INFECTIONS

UNIVERSITY OF VIRGINIA PA...

1. A method for inducing an immune response against a rhinovirus (RV) or for activating antigen-experienced RV-specific CD4+ T cells in a subject, said method comprising administering to said subject a pharmaceutical composition comprising an effective amount of at least one RV peptide epitope, wherein at least one of said RV peptide epitopes is a conserved RV peptide epitope recognized by antigen-experienced RV-specific CD4+ T cells, wherein said at least one RV peptide epitope is selected from the group consisting of SEQ ID NOs:1-53, 56, and 57, and biologically active fragments and homologs of said at least one RV peptide epitope.

US Pat. No. 10,368,367

METHOD AND APPARATUS FOR TRANSMITTING UPLINK SIGNAL IN WIRELESS LAN SYSTEM

LG ELECTRONICS INC., Seo...

1. A method of transmitting an uplink signal by a user equipment (UE) in a wireless communication system, the method comprising:receiving, by the UE, a Timing Advance (TA) command in subframe n; and
transmitting, by the UE, sidelink control information including TA information based on the TA command,
wherein the TA information is transmitted in fourth sidelink subframe from the subframe n, and
wherein when the UE transmits the sidelink control information at least two times within a sidelink control information period, the sidelink control information after a second transmission of the sidelink control information includes TA information included in a first transmission of the sidelink control information.

US Pat. No. 10,368,295

UNMANNED AERIAL VEHICLE GUIDANCE AND COMMUNICATION DEVICE WITH SYSTEM AND METHOD

FreeFlight Systems, Inc.,...

1. A guidance communication system comprising:a controller configured to manage flight path guidance data stored in a memory via a processor, the flight path guidance data configured to be updated via other data received via a receiver-transmitter, the flight path guidance data associated with at least one unmanned aerial vehicle in an environment controlled by the controller; and
at least one beacon configured to (i) be remotely deployed in the environment of the controller to define a flight path of the vehicle by transmitting the flight path guidance data to the vehicle, (ii) communicate with the receiver-transmitter of the controller via a beacon transmitter-receiver, and (iii) communicate with the vehicle via the beacon transmitter-receiver,
wherein,
the flight path includes a plurality of virtual lanes defined at least in part by the controller,
each of the plurality of virtual lanes has a direction of travel defined by the controller,
the plurality of virtual lanes include two adjacent lanes with opposite directions of travel defined by the controller,
the at least one beacon includes a plurality of beacons deployed in the environment of the controller to define at least a portion of the flight path,
each of the plurality of beacons spaced from each other at predetermined distances to provide redundancy such that, when one of the plurality of beacons is offline, one adjacent beacon maintains an adjacent portion of the flight path previously maintained by the one of the plurality of beacons that is offline, and
the adjacent portion of the flight path previously maintained by the one of the plurality of beacons that is offline is entirely maintained by only the one adjacent beacon so that all functionality of the offline beacon is maintained by the one adjacent beacon.

US Pat. No. 10,368,282

MODE CONTROL DESIGN

ITRON NETWORKED SOLUTIONS...

1. A method for optimizing communication modes between network nodes, comprising:storing, in a first node in a communication network, a data success rate for each of a plurality of communication modes;
receiving, by the first node, mode data from a second node in the communication network including at least a mode identifier for at least two of the plurality of communication modes;
determining, by the first node, a metric for each of the at least two communication modes based on at least a data success rate of transmissions using the respective communication mode;
selecting, by the first node, a preferred communication mode of the at least two communication modes based on the determined metric for each of the at least two communication modes; and
transmitting, by the first node, an initiation data message to the second node via the communication network indicating the selected preferred communication mode.

US Pat. No. 10,368,278

METHOD AND ENODEB FOR FORWARDING DOWNLINK AND UPLINK PACKETS BASED ON S1 HANDOVER

Huawei Technologies Co., ...

1. A method for forwarding uplink packets based on an S1 handover, the method comprising:forwarding, by a source evolved node (eNodeB), an uplink packet to a source serving gateway, wherein the uplink packet is successfully received from user equipment (UE);
discarding, by the source eNodeB, an uplink packet received out of sequence;
sending, by the source eNodeB, a packet data convergence protocol serial number (PDCP SN) to a target eNodeB in a control message,
wherein the PDCP SN is larger or equal to a maximum PDCP SN of the uplink packet;
sending, by the target eNodeB, packet state report information to the UE, wherein the packet state report information comprises the PDCP SN; and
receiving, by the target eNodeB, uplink packets from the UE, wherein the uplink packets include PDCP SNs that are equal to or larger than the PDCP SN of the packet state report information.

US Pat. No. 10,368,266

EFFICIENT UPLINK SCHEDULING MECHANISMS FOR DUAL CONNECTIVITY

Sun Patent Trust, New Yo...

1. A mobile node comprising:circuitry, which, in operation,
connects to a master base station and to a secondary base station via a split bearer that is split between the master base station and the secondary base station in a Packet Data Convergence Protocol (PDCP) layer;
determines whether a total buffer occupancy of the PDCP layer in the mobile node exceeds a threshold;
responsive to the total buffer occupancy exceeding the threshold, splits the total buffer occupancy of the PDCP layer into both a first PDCP buffer occupancy value for the master base station and a second PDCP buffer occupancy value for the secondary base station;
responsive to the total buffer occupancy not exceeding the threshold, splits the total buffer occupancy of the PDCP layer based on a defined split ratio into a first PDCP buffer occupancy value for the master base station and a second PDCP buffer occupancy value for the secondary base station, wherein the defined split ratio is configured such that one of the first and second PDCP buffer occupancy values is equal to the total buffer occupancy, and the other one of the first and second PDCP buffer occupancy values is equal to zero; and
a transmitter, which is coupled to the circuitry and which, in operation, transmits a first buffer status report based on the first PDCP buffer occupancy value to the master base station responsive to the first buffer occupancy value being more than zero, and a second buffer status report based on the second PDCP buffer occupancy value to the secondary base station responsive to the second buffer occupancy value being more than zero.

US Pat. No. 10,368,262

ENHANCING QUALITY OF SERVICE FOR HIGH PRIORITY SERVICES

Apple Inc., Cupertino, C...

1. A method for operating a user equipment device (UE) communicating with a packet switched network, the method comprising:at the UE:
establishing a first bearer having first quality of service (QoS) characteristics associated with a first priority, wherein the first bearer is a dedicated IP multimedia subsystem (IMS) signaling bearer used only for IMS signaling messages, wherein the first bearer is a default IMS signaling bearer, wherein the first QoS characteristics are identified by a QoS class identifier (QCI) value of 5;
establishing a second bearer having second QoS characteristics associated with a second priority lower than the first priority, wherein the second bearer is also a dedicated IMS signaling bearer used only for IMS signaling messages, wherein the second QoS characteristics are identified by a QCI value other than 5;
using the first bearer for communication for a first set of messages having the first priority; and
using the second bearer for communication for a second set of messages having the second priority.

US Pat. No. 10,368,254

DATA FORWARDING METHOD AND CONTROLLER

Huawei Technologies Co., ...

1. A controller comprising:a processor; and
a memory storing instructions that when executed by the processor configure the processor for:
obtaining first identification information of a terminal, wherein the first identification information comprises terminal capability information, service type information, and quality of service QoS information of the terminal;
obtaining information about an access standard supported by a network node accessed by the terminal;
determining N functional modules in L network nodes from M network nodes according to the first identification information, wherein the N functional modules are configured to process a data stream that corresponds to a service of the terminal; and
configuring, for the L network nodes, corresponding forwarding entries for forwarding the data stream, wherein the forwarding entries are used to enable the L network nodes to process the data stream by using the N functional modules,
wherein the determining the N functional modules in the L network nodes from the M network nodes according the first identification information comprises:
determining, according to the terminal capability information of the terminal, information about an access standard supported by the terminal;
determining an access standard of the terminal according to the information about an access standard supported by the terminal and the information about an access standard supported by a network node accessed by the terminal; and
selecting the N functional modules in the L network nodes from the M network nodes according to the access standard of the terminal, the service type information, and the QoS information.

US Pat. No. 10,368,235

WIRELESS DEVICE SIM ACTIVATION WHILE ROAMING

Apple Inc., Cupertino, C...

1. A method for activation of a subscriber identity module (SIM) of a universal integrated circuit card (UICC) included in a mobile device, the method comprising:by processing circuitry of the mobile device external to the UICC:
determining the SIM requires activation;
determining a geographic region for a mobile network operator (MNO) associated with the SIM;
determining a current geographic location of the mobile device; and
when i) the geographic region for the MNO associated with the SIM does not correspond to the current geographic location of the mobile device and ii) a data roaming capability of the mobile device is not enabled:
enabling the data roaming capability of the mobile device;
activating the SIM via a secure data connection between the UICC of the mobile device and a network-based server of the MNO associated with the SIM through a local roaming cellular wireless network; and
disabling the data roaming capability after activation of the SIM, wherein the mobile device is configured by default to not allow a roaming data connection to be established.

US Pat. No. 10,368,233

METHODS AND ARRANGEMENTS FOR TRACKING AND LOCATING LAPTOPS

Lenovo (Singapore) Pte. L...

1. A method comprising:obtaining, when a mobile device is not connected to a communications network and responsive to receiving an incorrect login attempt at the mobile device, data relating to a location of the mobile device using a receiver that receives the data from user devices in a vicinity of the mobile device, wherein the mobile device obtains an identifier broadcast from each of the user devices;
storing the data including the broadcast identifiers of the user devices within the mobile device;
thereafter transmitting, after establishing a communications network connection, the data including the broadcast identifiers of the user devices: and
determining, based on the received broadcast identifiers, a location of the mobile device: wherein the user devices comprise two or more fixed devices and mobile devices and wherein the data comprises two or more of: an access point ID, a cell phone tower ID, and signal strength information.

US Pat. No. 10,368,226

METHOD OF UPDATING A LOCATION INFORMATION REPRESENTING A PHYSICAL LOCATION OF A COMMUNICATION DEVICE, A COMPUTER PROGRAM PRODUCT FOR EXECUTING THE METHOD, AND A COMMUNICATION SYSTEM FOR UPDATING THE LOCATION INFORMATION

1. A method of updating location information, said location information representing a physical location of a communication device, wherein said location information is generated by a location source, and wherein said location information is sent from the location source to an electronic device having hardware comprising a processor, the method comprising:monitoring a second location information received subsequently to a first location information by the electronic device to detect an invalid location information included in the second location information, and,
in response to detection of the invalid location information, sending invalidation information indicating that location information of the first location information is invalid so that the first location information is discarded by non-transitory computer readable medium storing the first location information in response to the invalid location information.

US Pat. No. 10,368,223

LOW ENERGY AUDIO STREAMING

Orion Labs, San Francisc...

1. A method of transmitting audio data, the method comprising:a first communication device receiving over a low energy wireless communication link a plurality of audio data packet fragments from a second communication device, wherein each audio data packet fragment comprises audio data collected from an audio data stream;
the first communication device generating a plurality of audio data packets by assembling the received plurality of audio data packet fragments, wherein each audio data packet comprises a plurality of audio data packet fragments; and
the first communication device transmitting the plurality of audio data packets via a communication network.

US Pat. No. 10,368,216

LOCATION DETERMINATION SYSTEM HAVING MESH INFRASTRUCTURE TO REDUCE POWER CONSUMPTION

Sonitor Technologies AS, ...

1. A real-time location system in an environment, comprising:a location tag having a location ID, wherein the location tag is configured to transmit the location ID and a received acoustic ID from an acoustic transmitting device to a central server via a wireless mesh network;
the wireless mesh network comprising a first mesh network member and a second mesh network member, the first mesh network member and the second mesh network member being battery-powered devices, the first mesh network member having a first clock and the second mesh network member having a second clock, wherein the first mesh network member transmits a first timestamp of the first clock to the second mesh network member, and the second mesh network member generates a message for propagation to the central server, the message including identification of the first mesh network member and the second mesh network member, and the first timestamp and a second timestamp of the second clock; and
a central server configured to select a reference clock within the wireless mesh network, further configured to determine a time offset between the first clock and the reference clock based on the message; and further configured to propagate an acoustic transmission schedule to the first mesh network member,
wherein the first mesh network member and the location tag communicate acoustically based on the acoustic transmission schedule.

US Pat. No. 10,368,210

SERVICE PROCESSING METHOD, TERMINAL DEVICE, AND SERVICE ROAMING NETWORK

HUAWEI TECHNOLOGIES CO., ...

1. A service processing method, comprising:receiving, by a first local terminal, a service from a remote terminal using a mobile network,
determining, by the first local terminal, whether the service needs to be roamed by;
determining whether another local terminal that processes the service exists in the WiFi network; and
determining that the service needs to be roamed when the another local terminal that processes the service exists;
sending, by the first local terminal, a roaming request to a second local terminal when the service needs to be roamed, wherein the second local terminal is in communication with the first local terminal via the WiFi network;
receiving, by the first local terminal, a roaming response from the second local terminal;
and transferring, by the first local terminal, the service to the second local terminal.

US Pat. No. 10,368,208

LAYERS IN MESSAGING APPLICATIONS

APPLE INC., Cupertino, C...

1. A non-transitory machine readable medium storing executable program instructions which when executed by a data processing system cause the data processing system to perform a method comprising:receiving, by a first messaging app, a message from a second messaging app, the first messaging app and the second messaging app configured to communicate text messages through one or more messaging servers;
receiving, by the first messaging app, a first layer identifier associated with the message, the first layer identifier specifying, for a first layer, a Z depth of the first layer relative to at least one of one or more message bubbles in a sent message layer and one or more message bubbles in a received message layer in a message transcript;
receiving or generating, by the first messaging app, content for display in the first layer; and
displaying the sent message layer and a received message layer and the content in the first layer,
wherein the first layer is displayed at the Z depth relative to at least one of the one or more message bubbles in the sent message layer and the one or more message bubbles in the received message layer, and
wherein the sent message layer and the received message layer have different Z depths.

US Pat. No. 10,368,199

LOCATION SHARING

Apple Inc., Cupertino, C...

1. A method comprising:receiving, by a second device, a text message from a first device;
processing, by the second device, the text message to determine the text message includes at least a text string, the text string including:
(a) a first geographic location data associated with the first device, and
(b) a second geographic location data associated with the first device in the form of a first reduced size uniform resource locator (URL), the first reduced size URL reducing a size of the second geographic location data,
wherein the second geographic location data is contained in a longer URL, and
wherein the first reduced size URL is based on a hash of the longer URL;
presenting, by an application executing on the second device, at least part of the text string and the first reduced size URL;
obtaining, by the application, a first input to the first reduced size URL;
accessing, by a map service on the second device, a map service server based on the second geographic location data contained in the longer URL; and
presenting, by the second device in response to the obtained first input, a map display with a first location marker based on the second geographic location data.

US Pat. No. 10,368,176

EARPIECE FOR COUPLING A HEARING AID TO A USERS'S EAR CANAL AND A METHOD FOR MANUFACTURING SUCH AN EARPIECE

1. An earpiece for a hearing aid, the earpiece comprising:a seal configured to deform to a shape of a human ear canal,
wherein the seal is dome-shaped,
wherein the seal has a first section with a sound output bore and the sound output bore is configured to physically couple to a receiver for a hearing aid,
wherein the seal has a second section and the second section includes 50 to 2000 opening,
wherein the openings are laser-cut; and
wherein the openings have diameters from 80 to 150 micrometers.

US Pat. No. 10,368,171

AUDIO APPARATUS AND AUDIO OUTPUT PORT

RADSONE INC., Sungnam (K...

1. An audio apparatus comprising:an analog module configured to receive a digital left (L) channel signal and a digital right (R) channel signal, and output first and second analog L signals and first and second analog R signals;
a first output port including first to fifth conductors, to which the first and second analog L signals, the first and second analog R signals, and a ground voltage are provided, respectively; and
a second output port including sixth to ninth conductors, to which the first and second analog L signals and the first and second analog R signals are provided, respectively,
wherein, while an audio jack including first to third terminals remains inserted in the first output port, the first and second conductors remain connected to the first terminal, the third and fourth conductors remain connected to the second terminal, and the fifth conductor remains connected to the third terminal, and
wherein, while the audio jack remains inserted in the first output port, the first and second analog L signals and the first and second analog R signals are operated in a single-ended mode, and during at least a portion of a time during which the audio jack is not inserted into the first output port, the first and second analog L signals and the first and second analog R signals are operated in a differential mode.

US Pat. No. 10,368,167

AUDIO POWER CIRCUIT AND METHOD

MOTOROLA SOLUTIONS, INC.,...

1. An audio power circuit comprising:an audio amplifier having a power input;
a speaker connected to the audio amplifier;
a load switch coupled between a battery and the power input to selectively provide a supply of power from the battery to the power input;
a second load switch coupled between the battery and the power input in series with the load switch to selectively provide the supply of power from the battery to the power input;
a control circuit configured to be connected to the battery and the power input and to control the supply of power from the battery to the power input by controlling the load switch;
a thermal protection circuit connected between the audio amplifier and the speaker, the thermal protection circuit configured to generate a thermal protection signal and provide the same directly to the load switch to control the supply of power from the battery to the power input,
wherein the thermal protection circuit includes:
a comparator having a reference voltage input to receive a reference voltage, and a speaker voltage input to receive a speaker voltage, wherein the thermal protection circuit disables the supply of power from the battery to the power input by opening the load switch when the comparator indicates that the speaker voltage exceeds the reference voltage;
a rectifier connected to the speaker voltage input and configured to convert an alternating current (AC) voltage across the internal speaker to a direct current (DC) voltage, wherein the AC voltage is provided by the audio amplifier; and
a second thermal protection circuit connected between the audio amplifier and the speaker and in parallel to the thermal protection circuit, the second thermal protection circuit configured to generate a second thermal protection signal and provide the same directly to the second load switch to control the supply of power from the battery to the power input.

US Pat. No. 10,368,155

SYSTEM WITH WIRELESS EARPHONES

Koss Corporation, Milwau...

1. A wireless headphone assembly comprising:first and second earphones, wherein each of the first and second earphones comprises an acoustic transducer;
an antenna for receiving wireless signals;
a wireless communication circuit connected to the antenna, wherein the wireless communication circuit is for receiving and transmitting wireless signals to and from the wireless headphone assembly;
a processor in communication with the wireless communication circuit; and
a rechargeable battery for powering the wireless headphone assembly,
wherein the headphone assembly is configured, with the processor, to transition automatically from playing digital audio content received wirelessly by the headphone assembly via a first wireless network to playing digital audio content received wirelessly by the headphone assembly via a second wireless network.

US Pat. No. 10,368,154

SYSTEMS, DEVICES AND METHODS FOR EXECUTING A DIGITAL AUDIOGRAM

Listening Applications Lt...

1. A system for providing audio output, the system comprising:a remote computing device including a processor and an audio unit configured to generate one or more output signals of arbitrary amplitude;
earphones connectable to the computing device, configured to output said output signals; and
a microphone configured to record the power level of said output signals and calculate a proportionality constant for each frequency of said output signals; wherein said processor is further configured to:
analyze the proportionality constant for each frequency of one or more feedback signals from said one or more earphones to yield calibration data;
adjust the amplitude or frequency based at least on the calibration data to calibrate the device;
generate one or more audiograms resulting from a hearing test using the calibrated device; and
adjust a device power level according to said one or more audiograms.

US Pat. No. 10,368,124

REAL-TIME AUDIENCE MEASUREMENT SYSTEM

TiVo Solutions Inc., San...

1. A method comprising:receiving, at a first server, an instant message from a client system comprising television viewer data, wherein the television viewer data includes:
a user client operational command input
and an identity of media content and
the television viewer data specifies the first server as recipient of the instant message, wherein the instant message is sent over an SSL connection that is maintained between the first server and the client system, and wherein the SSL connection is automatically reconnected if the connection is dropped;
analyzing data from the television viewer data;
generating output information using the analyzed data; and
transmitting the output information using the analyzed data to a second server.

US Pat. No. 10,368,110

SMOOTH MEDIA DATA SWITCHING FOR MEDIA PLAYERS

VisualOn, Inc., San Jose...

1. A system for smooth media data switching, comprising:an interface to:
receive a potential change indication from a user of a potential change to a media player parameter of a current video stream the user is watching, wherein the potential change indication comprises zooming in on a particular video area of the current video stream, wherein the media player parameter comprises a viewing angle selection type; and
receive a change indication from the user to change the media player parameter of the current video stream; and
a processor to:
determine a plurality of predicted pre-buffer streams in response to the potential change indication from the user, wherein a plurality of viewing angle streams are related to the particular video area of the current video stream zoomed in on, wherein the plurality of predicted pre-buffer streams corresponds to a top N predicted potential changes to the media player parameter;
provide the plurality of predicted pre-buffer streams in addition to the current video stream to a user device associated with the user, wherein the plurality of predicted pre-buffer streams are provided to the user device for pre-buffering, wherein providing the plurality of predicted pre-buffer streams begins after the potential change indication from the user, wherein the plurality of predicted pre-buffer streams comprises a plurality of viewing angle streams; and
in response to the change indication to change the media player parameter, determine whether the change to the media player parameter of the current video stream corresponds to one of the plurality of predicted pre-buffer streams.

US Pat. No. 10,368,108

DOWNSTREAM VIDEO COMPOSITION

ATI Technologies ULC, Ma...

1. A method of multi-layered video processing video at a video source and a display device, said video source comprising a composition engine having a composition buffer, said method comprising:at said video source:
forming decoded video images by decoding a first input video bitstream comprising compressed video;
forming decoded overlay images by decoding a second input graphics bitstream received as an auxiliary bitstream in addition to the first input video bitstream and comprising graphics overlay data, said decoded overlay images associated with said decoded video images; and
forming a plurality of additional decoded overlay images from a plurality of additional input bitstreams comprising additional graphics overlay data;
compositing, via said composition engine, said additional decoded overlay images with said decoded overlay images formed from said second input graphics bitstream to form composited overlay images;
configuring said composition engine, capable of compositing images, to not composite said decoded overlay images with said decoded video images;
concurrently transmitting to said display device capable of compositing images, a first stream comprising said decoded video images and a second stream comprising said composited overlay images;
at said display device:
receiving said first and second streams;
selectively performing image processing on said received decoded video images, without having composited said overlay images with said received video images, to form enhanced video images;
compositing, pixels from each of said composited overlay images with respective pixels from each of said enhanced video images to form output images for display at said display device.

US Pat. No. 10,368,100

VIDEO DATA DECODING METHOD AND VIDEO DATA DECODING APPARATUS

Electronics and Telecommu...

1. A method for decoding video data comprising:receiving coded video data comprising video data and depth data corresponding to the video data;
acquiring motion data for inter-view prediction of a coding unit of the video data from the depth data;
performing inter-view prediction based on the motion data; and
reconstructing video data according to the video data comprising the coding unit and the depth data based on the inter-view prediction, the coding unit comprising at least one prediction block,
wherein the acquiring motion data for inter-view prediction of the coding unit comprises deriving the motion data for inter-view prediction of the coding unit based on a location and a size of the coding unit,
wherein the motion data for inter-view prediction of a prediction block of the video data is calculated using information derived from a depth map picture to which the coding unit refers, the information including the disparity of the maximum value of the depth values of a corresponding unit of the depth map picture to which the coding unit refers, and
wherein, in response to the coding unit comprising prediction blocks for which the inter-view predication is applied, the maximum value is shared in the prediction blocks for the motion data calculation of inter-view prediction.

US Pat. No. 10,368,097

APPARATUS, A METHOD AND A COMPUTER PROGRAM PRODUCT FOR CODING AND DECODING CHROMA COMPONENTS OF TEXTURE PICTURES FOR SAMPLE PREDICTION OF DEPTH PICTURES

NOKIA TECHNOLOGIES OY, E...

1. A method comprising:obtaining a depth view component map;
decoding one or both chroma components of a coded texture picture into one or two decoded chroma sample arrays;
obtaining a reference sample array on the basis of said one or two decoded chroma sample arrays by modifying said one or two decoded chroma sample arrays, said modifying comprising:
segmenting said one or two decoded chroma sample arrays, wherein said segmenting comprises creating a histogram of sample values of said one or two decoded chroma sample arrays;
replacing the sample values in each segment by a representative value of said each segment wherein the representative value is derived from comparing segments of the histogram sample values of said one or two decoded chroma sample arrays with sample values of one or more regions of the depth map and using the sample values of the depth region spatially overlapping a majority of samples of a chroma sample array segment as the values of respective samples in each segment; and
forming a decoded depth view component on the basis of said reference sample array.

US Pat. No. 10,368,086

IMAGE CODING/DECODING METHOD, DEVICE, AND SYSTEM

Huawei Technologies Co., ...

1. An image decoding method, comprising:performing, by a processor included in an image decoding device, singular vector decomposition on a prediction block corresponding to a to-be-decoded image block, to obtain eigenvector matrices U and V of the prediction block;
obtaining, by the processor, a transform coefficient;
decoding, by the processor, difference information of the eigenvector matrix U and difference information of the eigenvector matrix V, wherein the difference information of the eigenvector matrix U is difference information between an eigenvector matrix U of residual data and the eigenvector matrix U of the prediction block obtained after the singular vector decomposition, and wherein the difference information of the eigenvector matrix V is difference information between an eigenvector matrix V of the residual data and the eigenvector matrix V of the prediction block obtained after the singular vector decomposition;
acquiring, by the processor, the eigenvector matrices U and V of the residual data according to the eigenvector matrices U and V of the prediction block and the decoded difference information of the eigenvector matrix U and the decoded difference information of the eigenvector matrix V;
performing, by the processor, an inverse transformation on the transform coefficient based on the eigenvector matrices U and V of the residual data to obtain the residual data; and
obtaining an image block based on the residual data.

US Pat. No. 10,368,079

METHOD AND APPARATUS FOR IMAGE COMPRESSION THAT EMPLOYS MULTIPLE INDEXED COLOR HISTORY BUFFERS

ATI Technologies ULC, Ma...

1. A method for encoding a source image that is segmented into a plurality of sub-images each having a sub-image pixel width, comprising:encoding, by an encoder, different horizontal pixel slices of the plurality of sub-images using a plurality of indexed color history (ICH) buffers associated with the source image to produce encoded pixel data, each of the plurality of indexed color history (ICH) buffers configured to correspond to a single horizontal pixel slice of each sub-image; and
outputting, by the encoder, the encoded pixel data for the different horizontal pixel slices of the plurality of sub-images.

US Pat. No. 10,368,069

CODING UNIT QUANTIZATION PARAMETERS IN VIDEO CODING

Texas Instruments Incorpo...

1. A method of video encoding, comprising:dividing a picture into a plurality of non-over-lapping blocks;
for a first of the plurality of non-over-lapping blocks of a first size from a first portion of the picture, determine a first minimum coding unit size for which a first quantization parameter will be determined wherein the first minimum coding unit size is less than the first size;
for a second of the plurality of non-over-lapping blocks of a second size from a second portion of the picture, determine a second minimum coding unit size for which a second quantization parameter will be determined wherein the second minimum coding unit size is less than the second size;
transforming the plurality of non-over-lapping blocks into a plurality of transformed coefficients in a frequency domain using a transform function;
quantizing the plurality of transformed coefficients using a plurality of quantization parameters including the first quantization parameter and the second quantization parameter; and
encoding the plurality of quantized transformed coefficients into a bit stream and signaling at a picture level in the bit stream the minimum coding unit size for which the first quantization parameter is determined for the first non-over-lapping block and the minimum coding unit size for which the second quantization parameter is determined for the second non-over-lapping block.

US Pat. No. 10,368,055

ACTOR-MOUNTED MOTION CAPTURE CAMERA

Two Pic MC LLC, Burbank,...

1. An external three-dimensional camera system comprising a plurality of head-mounted cameras configured to capture images of at least a portion of an actor's face from at least two different angles, wherein at least two head-mounted cameras of the plurality of head-mounted cameras are independently adjustable in position with respect to one another.

US Pat. No. 10,368,020

IMAGE CAPTURING APPARATUS AND CONTROL METHOD THEREFOR

CANON KABUSHIKI KAISHA, ...

1. An apparatus including a sensing device capable of acquiring a phase difference signal for use in focus detection and a pixel signal for an image, the apparatus comprising:a controller having a processor which executes instructions stored in a memory or having circuitry, the controller being configured to function as:
a control unit configured to switch acquisition of the phase difference signal on an area-by-area basis in a frame in the sensing device, and
a correction unit configured to select defect information associated with the pixel signal acquired from the sensing device and correct the pixel signal based on the selected defect information,
wherein the memory stores the defect information which includes at least first defect information and second defect information in a same format as that of the first defect information,
the control unit has at least a first drive mode and a second drive mode in which the phase difference signal is acquired for an area different from an area for which the phase difference signal is acquired in the first drive mode, and
the correction unit switches defect information used, based on a change of an area in a frame in which the phase difference signal is to be acquired, and uses the first defect information in a case where, in a frame to be acquired, the control unit performs the control in the first drive mode while using the second defect information in a case where the control unit performs the control in the second drive mode.

US Pat. No. 10,368,018

IMAGE CAPTURING APPARATUS, CONTROL METHOD THEREFOR, IMAGE SENSOR, AND CONTROL METHOD THEREFOR

Canon Kabushiki Kaisha, ...

1. An image capturing apparatus comprising:a pixel area composed of a plurality of pixels arranged in a matrix;
a plurality of output circuits that apply preset processing to signals which are read out in parallel from a plurality of divided areas obtained by dividing the pixel area in a column direction and output the processed signals;
a controller that performs control to execute first driving multiple times for reading out signals for obtaining correction data from each of the divided areas to the output circuits, and second driving for reading out image signals from the divided areas to the output circuits;
a correction circuit that obtains the correction data from the signals which are read out through the first driving, and corrects the image signals using the correction data; and
a memory that stores area-to-area differences in the correction data obtained from the divided areas,
wherein the controller executes the first driving with respect to pixels in a part of rows that includes a row at a border of the divided areas,
the correction circuit obtains the correction data by, for each column, removing one or more outliers of the signals that have been read out multiple times, and averaging a remainder of the signals, and
the correction circuit corrects the image signals obtained from the divided areas using the area-to-area differences in the correction data.

US Pat. No. 10,368,012

IMAGE CAPTURE APPARATUS, IMAGE PROCESSING SYSTEM, AND CONTROL METHOD THEREOF

Canon Kabushiki Kaisha, ...

1. An image capture apparatus comprising:an image sensor having a plurality of pixels, wherein each of the plurality of pixels has a plurality of photoelectric conversion units that respectively receives luminous fluxes that have passed through different regions on an exit pupil of an optical system;
one or more processors; and
a memory storing instructions which, when the instructions are executed by the one or more processors, cause the image capturing apparatus to:
obtain a plurality of first image data respectively corresponding to the different regions of the exit pupil, and a second image data corresponding to a plurality of regions of the exit pupil;
reduce the plurality of first image data;
generate distribution data representing distribution of defocus amount in the plurality of first image data;
generate extracted data for obtaining distribution data having higher resolution than the distribution data based on the first image data and the second image data; and
output the extracted data, the distribution data, and the second image data to be recorded in the image capture apparatus or transmitted outside.

US Pat. No. 10,368,011

CAMERA ARRAY REMOVING LENS DISTORTION

1. A camera system comprising:a camera array comprising camera modules, the camera modules comprising a master camera that includes a processor, a memory, a sensor, a lens and a switch, the switch configured to instruct each of the camera modules to initiate a start operation to start recording video data using the lens and the sensor in each of the camera modules and the switch configured to instruct the camera modules to initiate a stop operation to stop recording; and
an aggregation system communicatively coupled to the camera array to receive the video data from the camera array, the aggregation system including code and routines stored on a non-transitory memory and configured to provide lens distortion correction for the video data when executed by the processor based on a forward model to map a three-dimensional real-world point onto an undistorted two-dimensional image by capturing the three-dimensional real-world point (V), determining a length of V by calculating a Euclidean norm, determining a normalized three-dimensional point (VN) by normalizing V, and determining an angle of VN;
wherein the camera modules of the camera array are configured to provide at least a 3× field of view overlap; and
wherein the camera array comprises equator camera modules that are arranged around an equator of the camera array so that the equator camera modules are adjacent to one another and configured to capture images having a same orientation relative to one another, wherein the same orientation is a portrait orientation or a landscape orientation of an optical sensor.

US Pat. No. 10,368,009

IMAGING APPARATUS

SONY CORPORATION, Tokyo ...

1. An imaging apparatus configured to be used on a vehicle, the imaging apparatus comprising:an image forming system configured to condense light received from an approaching vehicle that approaches the vehicle;
an imaging unit configured to:
receive the light condensed by the image forming system; and
photoelectrically convert the light;
a protection member configured to:
protect the imaging unit; and
optically transmit the light received from the approaching vehicle,
wherein the protection member is between the image forming system and the imaging unit such that an imaging unit side surface of the protection member is at an oblique angle to a light receiving surface of the imaging unit, and
wherein the light that passes through the protection member and reflects on the imaging unit towards the protection member is reflected back on the imaging unit towards a road surface; and
an absorbing member in a second direction that the imaging unit side surface of the protection member faces,
wherein the absorbing member is configured to absorb the light reflected back on the imaging unit towards the road surface.

US Pat. No. 10,368,002

CAMERA MODULES WITH AUTOFOCUS AND OPTICAL IMAGE STABILIZATION FUNCTIONS

CORNING INCORPORATED, Co...

1. A camera module comprising:an image sensor;
a lens assembly positioned to focus an image on the image sensor and comprising a liquid lens comprising a liquid interface; and
a mechanical actuator that causes relative translation between the lens assembly and the image sensor in each of an X-direction parallel to a first lateral axis and a Y-direction parallel to a second lateral axis, the first lateral axis substantially perpendicular to an optical axis of the lens assembly, and the second lateral axis substantially perpendicular to each of the optical axis and the first lateral axis;
wherein the lens assembly is fixed relative to the image sensor in each of a first rotational direction about the first lateral axis and a second rotational direction about the second lateral axis;
wherein a tilt of the liquid interface is adjustable to adjust a focal point of the lens assembly in at least one of the X-direction or the Y-direction to perform an optical image stabilization (OIS) function in two or more axes; and
wherein the liquid lens and the mechanical actuator cooperatively operate to perform the OIS function in four or more axes with mechanical motion limited to an X-Y plane.

US Pat. No. 10,367,996

CALIBRATING PANORAMIC IMAGING SYSTEM IN MULTIPLE DIMENSIONS

IEC Infrared Systems, LLC...

1. An apparatus employed in a panoramic imaging system, the apparatus comprising:one or more processors configured to:
produce image correction data for a lens associated with the panoramic imaging system or a sensor associated with the lens and the panoramic imaging system, where the image correction data is based on an error identified in an individual image acquired by the lens or sensor, where the individual image was acquired with a plurality of pre-determined operating parameters;
produce strip correction data for the lens or sensor, where the strip correction data is based on an error identified in a strip of images pieced together from a plurality of individual images acquired by the lens or sensor;
produce panoramic image correction data for the lens or sensor, where the panoramic image correction data is based on an error identified in a panoramic image pieced together from two or more strips of images pieced together from the plurality of individual images acquired by the lens or sensor; and
store, in a memory, the image correction data, the strip correction data, the panoramic image correction data, or a combined correction value computed from the image correction data, the strip correction data, and the panoramic image data, and data that relates the pre-determined operating parameters to the image correction data, the strip correction data, the panoramic image correction data, or the combined correction value.

US Pat. No. 10,367,992

IMAGE SENSOR AND ELECTRONIC APPARATUS

Sony Corporation, Tokyo ...

1. An image sensor comprising a plurality of pixels, each pixel including:one on-chip lens; and
a plurality of photoelectric conversion layers formed below the on-chip lens,
wherein each of at least two of the plurality of photoelectric conversion layers is split, partially formed, or partially shielded from light with respect to a light-receiving surface,
wherein the pixels are phase difference detection pixels for performing auto focus (AF) by phase difference detection, and
wherein a difference in output between the photoelectric conversion layers in the plurality of phase difference detection pixels is used for the phase difference detection.

US Pat. No. 10,367,984

METHOD OF FORMING CAMERA MODULE FOR VEHICULAR VISION SYSTEM

MAGNA ELECTRONICS INC., ...

1. A method of forming a camera module for a vision system for a vehicle, said method comprising:providing a circuit board, wherein the circuit board has an imager and associated circuitry disposed thereat;
providing a lens holder for holding a lens assembly, the lens assembly including a plurality of optical elements;
disposing an adhesive in an uncured state at one or both of the lens holder and the circuit board;
positioning the lens holder at the circuit board with the uncured adhesive disposed between and contacting the lens holder and the circuit board;
optically aligning the plurality of optical elements with the imager at the circuit board;
with the plurality of optical elements optically aligned with the imager at the circuit board, and with the adhesive between and contacting the lens holder and the circuit board, forming a lens holder and circuit board construction by curing the adhesive to an at least partially cured state to secure the lens holder relative to the circuit board;
with the adhesive cured to the at least partially cured state, placing the lens holder and circuit board construction in a first mold, wherein, when placing the lens holder and circuit board construction in the first mold, the lens holder and circuit board construction is datumed in the first mold by a portion of the lens holder;
forming an inner molded construction by molding, using a first polymeric resin, an inner molding over and around the circuit board and over a portion of the lens holder;
placing the inner molded construction in a second mold, wherein, when placing the inner molded construction in the second mold, the inner molded construction is datumed in the second mold by the portion of the lens holder; and
forming an outer molded construction by molding, using a second polymeric resin, an outer molding over the inner molding and over another portion of the lens holder to encase the inner molding.

US Pat. No. 10,367,981

PORTABLE ELECTRONIC DEVICE, IMAGE-CAPTURING MODULE THEREOF AND CARRIER ASSEMBLY THEREOF

AZUREWAVE TECHNOLOGIES, I...

1. An image-capturing module, comprising:a circuit substrate having a top surface and a bottom surface;
an image-sensing chip disposed on the bottom surface of the circuit substrate and electrically connected to the circuit substrate, wherein the image-sensing chip has an image-sensing area;
at least one electronic component disposed on the bottom surface of the circuit substrate and electrically connected to the circuit substrate;
a package structure disposed on the bottom surface of the circuit substrate to cover the at least one electronic component; and
a lens assembly including a holder structure disposed on the top surface of the circuit substrate and a lens structure being held by the holder structure and corresponding to the image-sensing area,
wherein the package structure surrounds the image-sensing chip, and a thickness of the package structure is greater than a thickness of the image-sensing chip;
wherein the image-capturing module further comprises at least one conductive body disposed on the bottom surface of the circuit substrate and electrically connected to the circuit substrate, the at least one conductive body is partially covered by the package structure, and a bottom surface of the at least one conductive body is exposed out of the package structure, wherein the package structure has a flattening surface flush with the bottom surface of the at least one conductive body, and wherein the circuit substrate has an unoccupied area that is disposed on the top surface thereof and surrounded by the holder structure.

US Pat. No. 10,367,979

IMAGE PROCESSING APPARATUS, IMAGING APPARATUS, DRIVER MONITORING SYSTEM, VEHICLE, AND IMAGE PROCESSING METHOD

KYOCERA Corporation, Kyo...

1. An image processing apparatus comprising:an image acquirer configured to acquire a captured image capturing a subject illuminated by light from at least one light source; and
a controller configured to generate adjustment information for adjusting an intensity of the light from the at least one light source on the basis of a size of a pupil of the subject determined from the captured image,
wherein the controller is configured to detect a first position where brightness is maximum within a predetermined region of the captured image that includes the pupil, a first brightness at the first position, a second position at a first distance from the first position in the captured image, and a second brightness at the second position, and determine the size of the pupil on the basis of the first brightness and the second brightness.

US Pat. No. 10,367,978

CAMERA SWITCHING METHOD AND ELECTRONIC DEVICE SUPPORTING THE SAME

Samsung Electronics Co., ...

1. An electronic device comprising:a housing;
a first camera;
a second camera;
a display;
a memory;
a processor; and
at least one sensor,
wherein the processor is configured to:
display image data obtained through the first camera or through the second camera on the display,
analyze sensing information obtained through the at least one sensor, and to determine whether a cover is in a first arrangement state or a second arrangement state based on the analyzed sensing information, wherein the first arrangement state corresponds to a state in which the cover covers at least a part of the first camera, the second arrangement state corresponds to a state in which the cover covers at least a part of the second camera disposed on another surface of the housing,
if it is determined that the cover is in the first arrangement state, switch a photographing unit from the first camera to second camera, and terminate displaying the image data on the display, and
if it is determined the cover is in the second arrangement state, set the first camera to a photographing ready state.

US Pat. No. 10,367,967

APPARATUS AND METHOD TO FACILITATE PRINTING OF CATALOG LABELS

1. An electronic device comprising:a memory storing a digital catalog;
at least one processor coupled to the memory, wherein the at least one processor is configured to:
determine that a printer is associated with the digital catalog if a match is found between printer identification information received from the printer and printer identification information stored in the memory,
determine that the printer is not associated with the digital catalog if a match is not found between printer identification information received from the printer and printer identification information stored in the memory,
receive a request for an item or part number in the digital catalog after determining that the printer is not associated with the digital catalog or after determining that the printer is associated with the digital catalog,
transmit a barcode associated with the requested item or part number to the printer after determining that the printer is not associated with the digital catalog or after determining that the printer is associated with the digital catalog,
transmit a print request to the printer to print the barcode after determining that the printer is not associated with the digital catalog or after determining that the printer is associated with the digital catalog, and
if the printer is not associated with the digital catalog, receive a barcode label print acknowledgment request after transmitting the print request to the printer to print the barcode.

US Pat. No. 10,367,954

INFORMATION PROCESSOR AND STORAGE MEDIUM STORING CONVERSION METHOD SETTING PROGRAM FOR CONVERTING USER READ INFORMATION IN ACCORDANCE WITH SELECTED CONVERSION METHOD

Seiko Epson Corporation, ...

1. A networked computer system that facilitates printing operations by authenticating a user prior to performing those printing operations, the networked computer system comprising:a multifunction machine that is structured to at least perform a printing operation on a medium, the multifunction machine connecting to a reading device configured to receive credentials of the user, the credentials being used to authenticate the user with the networked computer system in order to perform the printing operation; and
a server computer system, wherein the server computer system is in communication with the multifunction machine and is configured to at least partially control operations of the multifunction machine, including the printing operation, the server computer system comprising:
a processor configured to:
obtain read information read from an authentication medium by the reading device of the multifunction machine;
convert the read information in accordance with a selected conversion method, wherein the selected conversion method is one of a plurality of candidate conversion methods, and wherein selecting the selected conversion method is performed by the following selection method:
selecting a first candidate conversion method included within the plurality of candidate conversion methods;
converting the read information using the first candidate conversion method and performing a comparison between the converted read information and comparative-purpose authentication information; and
if a match is identified as a result of the comparison, selecting the first candidate conversion method as the selected conversion method, but if the match is not identified, repeating the selection method using a different candidate conversion method included within the plurality of candidate conversion methods until the match is identified;
to obtain the comparative-purpose authentication information that is used for the comparison with the read information after the read information is converted; and
to set, when the converted read information and the comparative-purpose authentication information match each other, the selected conversion method as a particular conversion method to be used to convert the read information read by the reading device.

US Pat. No. 10,367,953

IMAGE PROCESSING DEVICE WITH DESTINATION SELECTION INTERFACE

KABUSHIKI KAISHA TOSHIBA,...

1. An image processing device comprising:a display device configured to display a FAX destination registration screen having: a destination registration region in which a plurality of registered FAX destinations are displayed in a list, and a destination input region in which a plurality of selectable FAX destinations are displayed;
an input device configured to:
receive a destination registration input with respect to the destination input region, the destination registration input indicating a selected FAX destination from the plurality of selectable FAX destinations,
receive a registered destination selection input with respect to the destination registration region, the registered destination selection input corresponding to a registered FAX destination from the plurality of registered FAX destinations, and
receive a transmission input; and
a processor configured to:
in response to receiving the destination registration input indicating the selected FAX destination, control the display device to update the destination registration region so that the selected FAX destination is added to the registered FAX destinations displayed in the list,
in response to receiving the registered destination selection input, control the display device to display a pop-up screen including: destination information regarding the registered FAX destination corresponding to the registered destination selection input, and a selectable clear button, and
in response to an input corresponding to the clear button, control the display device to update the destination registration region so that the registered FAX destination corresponding to the registered destination selection input is removed from the registered FAX destinations displayed in the list, and
in response to the transmission input, transmit an image to each registered FAX destination displayed in the list.

US Pat. No. 10,367,950

DEVICE NOTIFICATION ADJUSTMENT DEPENDENT ON USER PROXIMITY

Lenovo (Singapore) Pte. L...

1. A method, comprising:detecting a received communication at a device;
detecting, using at least one device sensor, a device environmental context, wherein the device environmental context is detected using at least one of: device orientation, ambient light level, user biometric data, and connectivity status;
the detected device environmental context being associated in time with the received communication;
identifying a proximity of a user to the device by mapping the device environmental context to one of a plurality of user-proximity device contexts, each identifying a proximity of the user to the device; and
adjusting, based upon the user not being proximate to the device, the magnitude of the notification of the received communication from a notification sound value set before receipt of the communication to an increased adjusted value.

US Pat. No. 10,367,949

ECHO CANCELLER DEVICE AND VOICE TELECOMMUNICATIONS DEVICE

MITSUBISHI ELECTRIC CORPO...

1. An echo canceller device comprising:an adaptive filtering unit to perform a filtering operation using a filter-coefficient group on a sequence of reception signals input thereto, and to adaptively update the filter-coefficient group on a basis of a voice-transmission signal input thereto from a sound collector;
a false echo calculator to acquire current and previous filter-coefficient groups which have been used by the adaptive filtering unit, and to calculate false echo signals by performing filtering operations using the current and previous filter-coefficient groups, respectively, on the sequence of reception signals;
an evaluation value calculator to calculate evaluated values of an echo cancellation quantity corresponding to the respective false echo signals on a basis of the voice-transmission signal and the false echo signals;
a false echo selector to select, as an estimated echo component, a false echo signal from among the false echo signals on a basis of the evaluated values of the echo cancellation quantity; and
a signal output unit to output a residual signal indicating a difference between the estimated echo component and the voice-transmission signal.

US Pat. No. 10,367,945

PERFORMING CONTEXTUAL ANALYSIS OF INCOMING TELEPHONE CALLS AND SUGGESTING FORWARDING PARTIES

INTERNATIONAL BUSINESS MA...

1. A computer-implemented method comprising:receiving, by a computing device, an incoming telephone call from a caller;
identifying, by the computing device, a telephone number associated with the telephone call;
determining an identity of the caller based on the telephone number; and
using the identity of the caller to identify the location of the identified caller from a location sharing system;
predicting, by the computing device, one or more reasons for the telephone call based on the location of the identified caller; and
displaying, by the computing device, the one or more reasons for the telephone call.

US Pat. No. 10,367,936

AUTOMATIC DISTRIBUTION OF INMATE PHONE RECORDINGS

DSI-ITI, INC., Reston, V...

1. A non-transitory computer-readable medium storing instructions that, when executed by a processor, cause the processor to perform operations for automatically distributing a recording of a call to an interested party, the call being placed by a calling party through an institutional system to a destination number, the operations comprising:associating forwarding criteria with the interested party;
establishing the call from the calling party to the destination number through the institutional system;
recording the call;
determining that the call satisfies the forwarding criteria associated with the interested party;
after the call is completed, setting a data flag; and
in response to the data flag setting, automatically distributing the recording of the call to the interested party, wherein the interested party has been approved by a facility administration associated with the institutional system.

US Pat. No. 10,367,927

WEARABLE DEVICE WITH AN ANTENNA SYSTEM

LOGITECH EUROPE, S.A., L...

1. A wearable electronic device comprising:a first earphone and a second earphone;
a controller module that comprises:
a printed circuit board having a ground plane;
electrical components that include a transceiver; and
an antenna configured to wirelessly communicate with an external electronic device, wherein the antenna has a loop shape and comprises a first connection point that is electrically connected to the ground plane and a second connection point that is electrically connected to the transceiver; and
a cable having a first cable portion that includes one or more first conductors that electrically couple the electrical components of the controller module to the first earphone and a second cable portion that includes one or more second conductors that electrically couple the electrical components of the controller module to the second earphone, wherein
the first cable portion comprises a first shield surrounding the one or more first conductors and having a first length,
the second cable portion comprises a second shield surrounding the one or more second conductors and having a second length that is different from the first length,
the first and second shields are electrically coupled to a first point and a second point on the ground plane of the printed circuit board, respectively, and
the first length of the first cable portion and the second length of the second cable portion are designed to improve the efficiency of the antenna at a wireless communication frequency.

US Pat. No. 10,367,922

METHOD AND APPARATUS FOR SENDING TRANSMISSION CONTROL PROTOCOL TCP DATA PACKET AND SYSTEM

Huawei Technologies Co., ...

1. A method for sending a Transmission Control Protocol (TCP) data packet, wherein the method comprises:obtaining a first round-trip time of sending a TCP data packet in a network;
determining a second round-trip time, wherein the second round-trip time is a round-trip time that exists when a congestion window that is determined according to a first algorithm and a congestion window that is determined according to a second algorithm have an equal size, wherein in the first algorithm an increase step size of the congestion window is determined according to the first round-trip time, in the second algorithm an increase step size of the congestion window is determined according to the first round-trip time and a target throughput, and the target throughput is a throughput expected to be obtained for a service corresponding to the TCP data packet;
using the congestion window determined according to the first algorithm as a first congestion window when the first round-trip time is longer than the second round-trip time;
using the congestion window determined according to the second algorithm as the first congestion window when the first round-trip time is shorter than or equal to the second round-trip time; and
sending the TCP data packet by using the first congestion window.

US Pat. No. 10,367,918

SYSTEM TO DYNAMICALLY ADJUST REQUEST VALUES AT A BACK-END APPLICATION SERVER

HARTFORD FIRE INSURANCE C...

1. A system to improve an accuracy of information generated by a back-end application computer server, comprising:(a) a communication port to facilitate receipt of a plurality of data streams of electronic messages, each data stream being received from one of a plurality of remote third-party administrator computer servers via a distributed communication network;
(b) a data stream computer store to store information received in the data streams of electronic messages;
(c) a rules computer store to store different sets of pre-determined rules for different third-party administrator computer servers;
(d) the back-end application computer server, coupled to the communication port, the data stream computer store, and the rules computer store, programmed to:
(i) receive from the data stream computer store information associated with a set of requests from a first third-party administrator computer server, each request being associated with a request value,
(ii) retrieve from the rules computer store a first set of pre-determined rules for the first third-party administrator computer server,
(iii) automatically apply the first set of pre-determined rules to the set of requests from the first third-party administrator computer server, said application resulting in at least one adjusted request value for the set of requests and an overall value based at least in part on the request values and the adjusted request value associated with the set of requests,
(iv) automatically transmit a settlement instruction, including the overall value, to an electronic transaction system, and
(v) as a result of application of the first set of pre-determined rules, automatically transmit a flag to an electronic messaging communication server;
(e) the electronic transaction system to receive the settlement instruction and to execute a settlement transaction in accordance with the overall value; and
(f) the electronic messaging communication server to receive said flag, and as a result of receiving said flag, trigger an electronic notification from the electronic messaging communication server to the remote computer device associated with the first third-party administrator computer server.

US Pat. No. 10,367,917

METHOD AND APPARATUS FOR DYNAMICALLY LOCATING RESOURCES

Apple Inc., Cupertino, C...

1. A method comprising:identifying, by a processor of a client device, a remote location from a plurality of locations from which to obtain a resource, the identifying based on preference criteria and dynamically changing conditions, and wherein the preference criteria include configuration information including an address of the remote location for the resource stored on the client device;
transparently obtaining a later version of the resource from the identified location, wherein an earlier version of the resource, which was previously installed, is available for use at the client device even when the client device is disconnected from a network;
updating the configuration information based upon the obtained later version; and
updating the earlier version of the resource with the later version of the resource for use by a user of the client device, wherein the updating of the earlier version includes installing the later version of the resource on the client device.

US Pat. No. 10,367,916

ENHANCED FEATURE VECTOR

SAP SE, Walldorf (DE)

1. A method for controlling access by an application to features on a client device, the method comprising:receiving, from a server, a Feature Vector (FV) that particularly corresponds to the application, the FV listing one or more of the features on the client device that are to be unavailable to the application while the application executes, on the client device, in a container that has been extended through use of at least one plug-in that is particularly configured to provide the application access to one or more native functionality features on the client device;
processing aspects of the FV including storing at least a portion of the FV in a local repository on the client device;
accessing the stored portion of the FV in the local repository to determine an availability of a particular native functionality feature of the one or more native functionality features that are accessible to the application through the at least one plug-in; and
providing to the application an indicia of the availability of the particular native functionality feature based on determining that the particular native functionality feature is not listed in the stored portion of the FV.

US Pat. No. 10,367,915

OPTIMIZED IMAGE DELIVERY OVER LIMITED BANDWIDTH COMMUNICATION CHANNELS

1. A method of retrieving large-scale images over network communications channel for display on an internet-capable digital phone, the method comprising:issuing a first request for a first image data parcel from the internet-capable digital phone to a remote computer, wherein the first image data parcel and a second image data parcel are selected based on a same operator controlled image viewpoint on the internet-capable digital phone relative to a predetermined image and the first and the second image data parcels contain data that are used to generate a display on the internet-capable digital phone according to the same operator controlled image viewpoint;
wherein the predetermined image is processed to obtain a series K1-N of derivative images of progressively lower detail level, wherein each respective derivative image of the series is subdivided into a regular array wherein each resulting image data parcel of the regular array has a predetermined detail level, and wherein the resulting image data parcels are stored on the remote computer, the resulting image data parcels comprising the first and the second image data parcels;
receiving the first image data parcel from the remote computer over the network communications channels, the first image data parcel being sent by the remote computer in response to the first request;
displaying on the internet-capable digital phone at least part of the predetermined image using the first image data parcel received by the internet-capable digital phone, wherein the first image data parcel uniquely forms a discrete portion of the predetermined image according to the same operator controlled image viewpoint;
issuing a second request for the second image data parcel from the internet-capable digital phone to the remote computer; and
receiving the second image data parcel from the remote computer over the network communications channel, the second image data parcel being sent by the remote computer in response to the second request;
displaying on the internet-capable digital phone at least part of the predetermined image using the second image data parcel received by the internet-capable digital phone, wherein the second image data parcel uniquely forms a discrete portion of the predetermined image according to the same operator controlled image viewpoint;
wherein the first and the second requests are issued according to prioritization from among a plurality of image data parcels selected for same operator controlled viewpoint.

US Pat. No. 10,367,910

INSTANTANEOUS NON-BLOCKING CONTENT PURGING IN A DISTRIBUTED PLATFORM

Verizon Digital Media Ser...

1. A computer-implemented method for non-blocking content purging, the method comprising:caching a plurality of content to memory of a content distribution server with a first timestamp corresponding to a time at which each content of the plurality of content is cached to the memory;
providing, by the content distribution server, a different second timestamp to a command designating removal of particular content from said memory, wherein the particular content is part of the plurality of content cached to said memory, and wherein the second timestamp corresponds to a time at which the command is received at the content distribution server;
maintaining a copy of the particular content in said memory in response to said command and before the content distribution server receives a user request for the particular content;
receiving by the content distribution server, a user request for the particular content; and
executing by the content distribution server, a cache miss, in response to the user request, based on the first timestamp of the particular content being older than the second timestamp of the command, wherein executing the cache miss comprises replacing the copy of the particular content in said memory with an updated copy retrieved from an origin server and sending the updated copy in answer to the user request.

US Pat. No. 10,367,896

SERVICE LAYER SESSION MIGRATION AND SHARING

Convida Wireless, LLC, W...

1. A node comprising a processor, a memory, and communication circuitry, the node being connected to a communications network via its communication circuitry and operating as a gateway or server in the network, the node further including computer-executable instructions stored in the memory of the node which, when executed by the processor of the node, perform functions of an instance of a service layer of the network and cause the node to:store, in the memory of the node, context comprising information concerning a communication session established between the service layer instance of the node and an application executing on a second node connected to the network; and
in response to a trigger condition indicating that the communication session between the service layer instance of the node and the application of the second node is to be migrated to or shared with a third node, transmit the stored context for the communication session from the node to a service layer instance executing on the third node.

US Pat. No. 10,367,879

DOWNLOAD PRIORITIZATION

Apple Inc., Cupertino, C...

1. A non-transitory machine-readable medium containingexecutable program instructions which when executed by a device cause the device to perform a method comprising:
receiving, from one or more processes running on the device, a plurality of download requests, wherein each download request corresponds to a request for a respective object;
determining a priority hint associated with a process running on the device;
scheduling, based on at least the priority hint associated with the process, a download request from the plurality of download requests;
based on the scheduling of the download request, starting a download process using the scheduled download request to download an object corresponding to the download request;
determining that a change has occurred in the priority hint during the download process;
based on determining that the change occurred, changing a characteristic of the download process; and
storing the object corresponding to the download process.

US Pat. No. 10,367,875

METHOD AND SYSTEM FOR DYNAMIC RATE ADAPTATION OF A STREAM OF MULTIMEDIA CONTENTS IN A WIRELESS COMMUNICATION NETWORK

Telecom Italia S.p.A., M...

1. A method of downloading a multimedia content from a server to a client device through a wireless communication network, the multimedia content being subdivided into a plurality of portions and for each portion the server storing a plurality of versions thereof each of which is encoded with a specific encoding quality, the method comprising:selecting, by the client device and among the plurality of versions of each portion of the multimedia content, a version of the portion of the multimedia content to be downloaded based on wireless communication parameters determined at at least two different layers of a wireless communication network OSI protocol stack at the client device, wherein the wireless communication parameters determined at the at least two different layers of the wireless communication network OSI protocol stack at the client device comprise first wireless communication parameters determined at an application layer of the OSI protocol stack, and wherein the first wireless communication parameters comprise a streaming service quality of the download of the multimedia content from the server to the client device determined at the application layer of the OSI protocol stack.

US Pat. No. 10,367,872

CLOUD-BASED VIDEO DELIVERY

Brightcove, Inc., Boston...

1. A method of making media content available for delivery via a data communications network, the method comprising:receiving, via a communications interface, a request to make media content available for delivery;
obtaining, via the communications interface, a media file having the media content;
determining a plurality of media profiles, based on the request, wherein:
each media profile of the plurality of media profiles determines one or more video playback properties of a respective output media file; and
the plurality of media profiles includes:
a first set of media profiles, and
a second set of media profiles;
transcoding, with a processing unit, the media file in accordance with the first set of media profiles to create a first set of output media files;
transcoding, with the processing unit, the media file in accordance with the second set of media profiles to create a second set of output media files, wherein the second set of output media files includes an output media file having one or more video playback properties different than each output media file of the first set of output media files;
subsequent to creating the first set of output media files, sending the first set of output media files to one or more distributed servers; and
subsequent to sending the first set of output media files to the one or more distributed servers, and prior to completing the transcoding of the media file in accordance with the second set of media profiles, sending a notification that the media content is available for delivery using at least the first set of media profiles, based on a determination that the media file has been transcoded in accordance with the first set of media profiles.

US Pat. No. 10,367,846

SELECTIVELY CHOOSING BETWEEN ACTUAL-ATTACK AND SIMULATION/EVALUATION FOR VALIDATING A VULNERABILITY OF A NETWORK NODE DURING EXECUTION OF A PENETRATION TESTING CAMPAIGN

XM Cyber Ltd., Hertzliya...

1. A method for penetration testing of a networked system by a penetration testing system using both active and passive validation methods wherein the penetration testing system is controlled by a user interface of a computing device, the method for penetration testing comprising:a. receiving, by the penetration testing system and via the user interface of the computing device, one or more manually-entered inputs;
b. determining a first target network node of the networked system to be the next network node to attempt to compromise;
c. determining a first vulnerability of network nodes to be used for compromising the first target network node;
d. determining a first damage to the first target network node that can be caused by validating the first vulnerability for the first target network node by using active validation;
e. selecting a first validation method for validating the first vulnerability for the first target network node, a type of the first validation method being:
A. selected from the type group consisting of active validation and passive validation; and
B. associated with the first damage;
f. validating the first vulnerability for the first target network node using the first validation method;
g. determining a second target network node of the networked system to be the next network node to attempt to compromise;
h. determining a second vulnerability of network nodes to be used for compromising the second target network node;
i. determining a second damage to the second target network node that can be caused by validating the second vulnerability for the second target network node by using active validation;
j. selecting a second validation method for validating the second vulnerability for the second target network node, a type of the second validation method being:
A. selected from the type group consisting of active validation and passive validation;
B. associated with the second damage; and
C. different from the type of the first validation method;
k. validating the second vulnerability for the second target network node using the second validation method; and
l. reporting at least one security vulnerability of the networked system determined to exist based on results of performing steps b-k, wherein the reporting comprises performing at least one operation selected from the group consisting of: (A) causing a display device to display a report containing information about the at least one security vulnerability of the networked system, (B) storing the report containing information about the at least one security vulnerability of the networked system in a file and (C) electronically transmitting the report containing information about the at least one security vulnerability of the networked system,wherein all of steps b-l are performed by the penetration testing system, and wherein the one or more manually-entered inputs received via the user interface explicitly define at least one item selected from the group consisting of (i) a type of a validation method associated with the first damage, and (ii) a type of a validation method associated with the second damage.

US Pat. No. 10,367,844

SYSTEMS AND METHODS OF NETWORK SECURITY AND THREAT MANAGEMENT

MASERGY COMMUNICATIONS, I...

12. A network security and threat management system, comprising:a computer configured to:
receive traffic information generated based, at least in part, upon an analysis of packets directed to a plurality of enterprise assets, wherein the traffic information includes a resource violation message reporting an unknown client's attempt to use an unknown protocol;
receive vulnerability information generated based, at least in part, upon an analysis of one or more of the plurality of enterprise assets;
receive vendor alert information provided by one or more third-party vendors;
continuously correlate:
the received traffic information, vulnerability information, and vendor alert information;
assign threat points to each of the plurality of security threats based, at least in part, upon the continuous correlation, wherein to assign the threat points the computer is further configured to:
upgrade the threat points associated with the given security threat in response to the traffic information being correlated with the vulnerability information;
upgrade the threat points associated with the given security threat in response to the traffic information being correlated with the vendor alert information; and
upgrade the threat points associated with the given security threat in response to the vulnerability information being correlated with the vendor alert information; and
dynamically adjust a priority of a given one of the plurality of security threats by escalating a security threat with a highest potential to be successful and modifying a risk associated with other security threats based, at least in part, upon the continuous correlation and upon an age of the given one of the plurality of security threats,
wherein escalating the security threat with the highest potential to be successful comprises identifying, based on an age of the vulnerability information, an enterprise asset of the plurality of enterprise assets being vulnerable to the security threat and the age of the vulnerability information with respect to the security threat.

US Pat. No. 10,367,836

METHOD AND APPARATUS FOR DETECTING ABNORMAL STATE OF BEACON DEVICE IN WIRELESS MESH NETWORK AND RECORDING MEDIUM STORING COMPUTER PROGRAM FOR EXECUTING THE METHOD

SK PLANET CO., LTD., Seo...

7. A service device for providing service information corresponding to beacon identification information to a plurality of user terminal devices through a communication network, the service device comprising:a communicator configured to:
communicate with a beacon device and the user terminal device, respectively; and
collect information regarding service traffic of the beacon device;
a processor configured to:
collect statistical data regarding the service traffic of the beacon device in a normal state;
monitor service traffic generated between the service device and the plurality of user terminal devices;
determine a state of the beacon device corresponding to the beacon identification information based on a variation of an amount of service traffic, wherein the beacon identification information is assigned to each beacon device;
receive, from the user terminal device, a service request based on the beacon identification information;
identify the service information stored in a memory that is corresponding to the beacon identification information; and
transmit, to the user terminal device, the identified service information corresponding to the beacon identification information; and
the memory configured to:
store the service information corresponding to the beacon identification information; and
store an average amount of the service traffic of the beacon device in the normal state based on the collected statistical data, wherein
the communicator is further configured to periodically receive, from the beacon device, a state check message; and
the processor is further configured to:
determine whether the service traffic of the beacon device is valid based on the received state check message; and
control the beacon device such that the beacon device changes channels.