US Pat. No. 10,167,239

PELLETED FEATHER MEAL AND SOYBEAN MEAL BASED ORGANIC FERTILIZER

True Organic Products, In...

1. A pelleted feather meal, soybean meal, and meat and bone meal based organic fertilizer product, wherein the pelleted feather meal, soybean meal, and meat and bone meal based organic fertilizer product is produced from a process including:obtaining a quantity of feather meal;
obtaining a quantity of soybean meal;
obtaining a quantity of meat and bone meal;
combining at least part of the quantity of the feather meal, at least part of the quantity of the soybean meal, and at least part of the quantity of meat and bone meal to create a combination of feather meal, soybean meal, and meat and bone meal, where the combination of feather meal and soybean meal is at least 70% of the entire combination; and
processing the combination of feather meal, soybean meal, and meat and bone meal to create a pelletized blend feather meal and soybean meal based organic fertilizer product.

US Pat. No. 10,167,236

METHOD FOR PROVIDING AN INORGANIC COATING TO AMMONIUM NITRATE-BASED PARTICLES

YARA INTERNATIONAL ASA, ...

20. A method for reducing caking of an ammonium nitrate-based fertilizer, the method comprising applying the inorganic coating according to 13 on a particulate ammonium nitrate-based fertilizer.

US Pat. No. 10,167,210

METHODS FOR CONSERVING RESOURCES BY TREATING LIQUIDS WITH ELECTROMAGNETIC FIELDS

Reverse Ionizer Systems, ...

1. A method for conserving resources comprising:receiving data, representative of one or more resources of a transport system or reference system affected by treatment of unwanted material in a liquid, at a user control system or an agent control system (collectively “control system”),
computing an indication of the difference between an amount of resources currently being used by the transport system or the reference system based on the received data and a threshold amount of resources at the control system; and
wherein the treatment of the unwanted material in the liquid comprises generating and applying a magnetic field that includes a modulation signal corresponding to an ionic cyclotron frequency of the unwanted material to treat the unwanted material in the liquid using at least two immersible radial coils configured in a Helmholtz coil arrangement, and at least two axial coils.

US Pat. No. 10,167,182

VACUUM SIDE AIR VENT

The Coca-Cola Company, A...

1. A method for removing air within an air chamber, comprising:receiving a flow of a fluid at a first port of the air chamber from a fluid source in fluid communication with the air chamber;
dispensing the fluid at a second port of the air chamber; and
reversing the flow to draw the fluid into the air chamber to purge air within any one of the air chamber and the fluid source through a third port by reversing a pump.

US Pat. No. 10,167,174

ELECTROMAGNETIC LIFTER FOR HOT MATERIALS

SGM MAGNETICS S.P.A., Ma...

1. An electromagnetic lifter for moving hot materials, comprising:a ferromagnetic yoke formed by at least one horizontal core and a plurality of vertical polarities;
a plurality of coils wound around said at least one horizontal core and enclosed in a container;
a non-magnetic baffle arranged between the plurality of vertical polarities and below said container, the non-magnetic baffle adapted to protect the container from heat radiated by a hot material to be moved;
a first space between the container and the plurality of vertical polarities, the first space adapted to maintain a first predetermined distance between the container and the plurality of vertical polarities and to prevent contact between the container and the plurality of vertical polarities;
a second space between the container and the core, the second space adapted to maintain a second predetermined distance between the container and the core and to prevent contact between the container and the core;
a plurality of side spacers disposed in the first space between the container and the plurality of vertical polarities, the plurality of side spacers adapted to maintain the first predetermined distance between the container and the plurality of vertical polarities; and
a plurality of top spacers disposed in the second space between the container and the core, the plurality of top spacers adapted to maintain the second predetermined distance between the container and the core.

US Pat. No. 10,167,159

APPARATUS AND METHODS FOR TRANSPORTING WEBS OF MATERIAL

Curt G. Joa, Inc., Shebo...

1. A system comprising:a conveyor comprising a material surface for moving a web material along a transfer path;
a plurality of holes formed through the material surface, the plurality of holes in fluid communication with a cavity;
a fan plate for drawing air out of the cavity to cause air to flow through the holes and into the cavity, the fan plate being oriented substantially perpendicular to the conveyor;
wherein the fan plate is driven by the conveyor.

US Pat. No. 10,167,156

VACUUM COMMUTATION APPARATUS AND METHODS

Curt G. Joa, Inc., Shebo...

2. A system for processing a web, the system comprising:a rotating external porous roll rotating at a first rotational speed;
a rotating internal vacuum manifold communicatively coupled with at least a portion of said rotating external porous roll, said rotating internal vacuum manifold rotating at a variable rotational speed, from a second speed less than said first rotational speed, to said first rotational speed, to a third speed greater than said first rotational speed.

US Pat. No. 10,167,123

NON-REMOVABLE TAMPER RESISTANT LID

1. A tamper resistant lid comprising:a centre axis;
an outer member;
an inner member;
the outer member and the inner member each comprise an outer surface, an inner surface, a circular base having a circular wall extending around a periphery of the circular base wherein a distal surface of a distal end of the inner member comprises a first tilting surface inclined in a distal direction from the inner surface toward the outer surface of the inner member, and the outer member comprises a second tilting surface arranged on a proximal surface of a circumferential lock flange at a distal end of the outer member, the second tilting surface inclined in a proximal direction toward the centre axis of the tamper resistant lid, the first tilting surface and the second tilting surface providing a hook like lock configuration of the inner member with respect to the outer member; and
the outer member comprises at least one stop member, the at least one stop member having a third tilting surface.

US Pat. No. 10,167,122

NON-REMOVABLE TAMPER RESISTANT LID

1. A method for sealing a container comprising:providing a tamper resistant lid comprising a centre axis; an outer member; an inner member; the outer member and the inner member each comprise an outer surface and an inner surface wherein at least a part of the outer surface of the inner member is adjacent at least a part of the inner surface of the outer member, the inner member having a thread; and at least one stop member preventing the inner member from rotation with respect to the outer member,
placing the tamper resistant lid onto a container;
rotating the outer member in a first direction to allow the thread of the inner member to connect to a thread of a neck element of the container; and
disabling the at least one stop member by rupturing the at least one stop member by applying a designated force after the inner member has been connected to the container, so that the outer member can be freely rotated with respect to the inner member to thereby prevent removal of the tamper resistant lid from the container.

US Pat. No. 10,167,111

TAMPER-EVIDENT REUSABLE PACKAGE CLOSURE

VELCRO BVBA, Deinze (BE)...

1. A reusable closure system, comprising:a base configured to be bonded to underlying package material and including a first field of touch fasteners having one or more cut-lines therein defining a hinged pull-tab assembly; and
a hinged lid configured for movement between open and closed positions relative to the base and including a second touch fastener field that is complementary to the first touch fastener field, such that the first and second touch fastener fields engage with one another to provide a secure closure when the lid is in the closed position;
wherein upon opening of the lid, the hinged pull-tab assembly is exposed so that the pull-tab assembly can be selectively peeled back to its hinge while simultaneously removing a frangible region of the packaging material to which the base can be bonded to form a resulting hole in the packaging material, and so that the peeled-back pull-tab assembly can be securely stowed against the lid by operation of the first and second touch fastener fields thereby providing a lid-based plug configured to engage the resulting hole in the packaging material when the lid is in the closed position.

US Pat. No. 10,167,099

APPARATUS AND METHOD FOR EXPANDING AND ERECTING COLLAPSED OR FOLDED CARDBOARD PACKAGINGS TO STANDING ARRANGED COMPARTMENTS AND/OR OUTER PACKAGINGS

Krones Aktiengesellschaft...

1. An apparatus (01) for expanding and erecting collapsed or folded cardboard packagings (02) to standing compartments and/or outer packagings (03), comprising:a cardboard packaging supply (04) comprising at least one stack (41) of flatly collapsed cardboard packagings (02) arranged lying on top of each other,
an erecting device (05) arranged next to the cardboard packaging supply (04) as seen in the direction of a horizontal axis (11), and
a gripping device (06) for the simultaneous seizing one topmost cardboard packaging (02) from each stack (41) of the cardboard packaging supply (04), wherein:
the cardboard packagings (02) comprise a plurality of cardboard packaging walls (22) interconnected with each other, one forming a top flat side (23) and one forming a bottom flat side (24) of a flatly collapsed cardboard packaging (02),
the gripping device (06) has at least one tool (61) for holding the top flat side (23) of the cardboard packaging wall (22),
the gripping device (06) has at least one manipulator (62) with a manipulator head (63) that is at least movable along a horizontal axis (11), wherein the at least one tool (61) is arranged at the manipulator head (63) so that the at least one tool (61) is movable at least horizontally between the cardboard packaging supply (04) and the erecting device (05),
the erecting device (05) has at least one carrier (51) that is rotatable about a horizontal pivoting axis (13) from a horizontal position to a vertical position and vice versa,
the erecting device (05) has at least one tool (52), arranged at its at least one carrier (51), for each cardboard packaging (02) that is simultaneously seizable by the gripping device (06),
the at least one tool (52), in its horizontal position, seizes each cardboard packaging (02), at its bottom flat side (24),
each cardboard packaging (02) is expanded to a set of compartments and/or to an outer packaging (03) by an increase of the distance between the at least one tool (61) of the gripping device (06) and the at least one tool (52) of the erecting device (05) along a vertical axis (12), and
the at least one tool (52) holds each cardboard packaging (02) at least until the at least one carrier (51) has rotated about the horizontal pivoting axis (13) from its horizontal position into its vertical position so that access openings through which articles can be introduced into the expanded compartments and/or outer packaging (03) are in a vertical plane.

US Pat. No. 10,167,076

CORRUGATED LIFT FAN ROTOR

Kitty Hawk Corporation, ...

1. A rotor, comprising:an upper skin;
a lower skin; and
an at least partly corrugated core encased between the upper skin and the lower skin;
wherein the core includes a first portion associated with a central disk portion of the rotor and a second portion associated with one or more rotor blade portions of the rotor.

US Pat. No. 10,167,072

ATMOSPHERIC BALLOON DESCENT SYSTEM

Raven Industries, Inc., ...

1. An atmospheric balloon descent system comprising:a system housing including a drogue chamber and a parachute chamber, the system housing includes:
a drogue cover, the drogue cover configured to open the drogue chamber, and
a parachute cover, the parachute cover configured to open the parachute chamber;
a drogue chute within the drogue chamber;
a parachute within the parachute chamber, the parachute coupled with the drogue chute with a drogue tether; and
a riser tether assembly coupled with the parachute, the riser tether assembly includes:
a riser tether extending between a descent system end portion and a balloon system end portion, the descent system end portion coupled with the parachute, and
a drogue cover release coupled between the riser tether and the drogue cover.

US Pat. No. 10,167,061

BUOYANCY DEVICE FOR VERY DEEP WATER AND PRODUCTION METHOD THEREOF

Saipem S.p.A., San Donat...

1. A buoyancy device, comprising:a support structure which can be connected to one of an underwater installation and an underwater vehicle,
one or more buoyancy spheres connected to the support structure, said buoyancy spheres having a specific weight of less than 500 kg/m3, and a metal spherical shell defining a spherical inner volume and which has an outer diameter greater than 0.5 cm, and a radial thickness greater than 0.08 mm, wherein the spherical shell is obtained in one piece in nano-crystalline metal with an average grain size of less than 1000 nanometers.

US Pat. No. 10,167,052

LINEAR GEAR SHIFT MECHANISM FOR CHAINLESS VEHICLE

MOTIVE POWER INDUSTRY CO....

1. A linear gear shift mechanism for chainless vehicles, comprising:a gear shift unit having a support rotator, a plurality of transmission balls and a plurality of driving posts, with the transmission balls spaced apart from each other and movably disposed on the support rotator, with a cylindrical receiving portion disposed on each said transmission ball along a radial direction thereof, wherein the driving posts have inward ends movably disposed in the cylindrical receiving portions, respectively, along a radial direction of the support rotator and rotate from the radial direction of the support rotator to but not reach an axial direction of the support rotator;
an axial power input rotator having an inward-tilted power input annular surface and inputting power along the axial direction of the support rotator;
an axial power output rotator having an inward-tilted power output annular surface and outputting power along the axial direction of the support rotator, wherein the transmission balls are movably clamped between the inward-tilted power input annular surface, the inward-tilted power output annular surface and the support rotator;
a transverse power source for meshing with the axial power input rotator along the radial direction of the support rotator;
an axial power transfer portion for meshing with the axial power output rotator along the axial direction of the support rotator; and
a transverse power output portion for meshing with the axial power transfer portion along the radial direction of the support rotator;
wherein the axial power input rotator and the axial power output rotator are disposed on two opposite sides of the transmission balls, respectively, to movably clamp the transmission balls between the inward-tilted power input annular surface, the inward-tilted power output annular surface and an outer circumferential surface of the support rotator, with the cylindrical receiving portion being a cylindrical receiving recess, wherein the inward ends of the driving posts are movably disposed in the cylindrical receiving recesses, respectively, along the radial direction of the support rotator, wherein the gear shift unit has a driving ring, wherein outward ends of the driving posts are pivotally connected to the driving ring, and the driving ring moves along the axial direction of the support rotator.

US Pat. No. 10,166,999

SURROUND SOUND BASED WARNING SYSTEM

Ambarella, Inc., Santa C...

1. An apparatus comprising:an interface configured to receive data readings generated by a plurality of sensors; and
a processor configured to (a) perform a fusion operation on said data readings from said plurality of sensors to detect an event, (b) determine a location of said event with respect to a vehicle based on said data readings, (c) convert said location to spatial audio data and (d) generate an audio warning signal based on said spatial audio data, wherein (i) at least one of said sensors generates video data as one of said data readings, (ii) said processor performs video analysis on said video data to calculate measurements using a number of pixels to said event with respect to said vehicle to calculate said location, (iii) said spatial audio data is in a format compatible with a surround sound speaker system of said vehicle, (iv) said audio warning signal indicates said location of said event using said surround sound speaker system, (v) said fusion operation makes inferences from said plurality of sensors not possible from one of the sensors alone, (vi) said spatial audio data is configured to correlate said location of said event to a user location within said vehicle, (vii) one of said sensors comprises an interior camera and (viii) said processor is further configured to analyze video data from said interior camera to determine said user location.

US Pat. No. 10,166,947

SEALED WEB RETRACTORS FOR PERSONAL RESTRAINT SYSTEMS AND ASSOCIATED SYSTEMS AND METHODS

Shield Restraint Systems,...

1. A web retractor for use with an occupant restraint system in a vehicle, the web retractor comprising:a frame having a sidewall with a first opening;
a locking assembly having a housing with a second opening, wherein the housing is attached to the sidewall of the frame with the second opening adjacent to the first opening;
a spool shaft configured to carry a web wound thereon;
a shaft coupler operably coupling the shaft to the locking assembly through the first and second openings; and
at least one seal operably positioned in the first opening between the shaft coupler and the sidewall, wherein the shaft coupler is rotatably and sealably carried by the sidewall.

US Pat. No. 10,166,946

VEHICULAR AIRBAG DEVICE

AUTOLIV DEVELOPMENT AB, ...

1. A vehicular airbag device comprising an airbag which opens an airbag door openably sealing an opening formed on an instrument panel, which deploys and expands rearward in a vehicle longitudinal direction from the opening toward an occupant sitting on a front seat of a vehicle, and which is configured to contact the occupant while being supported by the instrument panel, whereinan outer shape of the airbag when fully deployed and expanded is line-symmetrical with respect to a center line of the opening in a vehicle left-right width direction, and a width dimension in the vehicle width direction at a rear edge position of the instrument panel in the vehicle longitudinal direction is greater than a width dimension in the vehicle width direction at a center position of the opening in the vehicle longitudinal direction which is more forward in the vehicle longitudinal direction than the rear edge position of the instrument panel,
wherein the width dimension in the vehicle width direction at the rear edge position of the instrument panel and the width dimension in the vehicle width direction at the center position of the opening in the vehicle longitudinal direction which is more forward in the vehicle longitudinal direction than the rear edge position of the instrument panel are both greater than a maximum width dimension in the vehicle width direction at a vertical section including an apex position of the airbag which is more rearward in the vehicle longitudinal direction than the rear edge position of the instrument panel.

US Pat. No. 10,166,942

MOTOR VEHICLE SEAT ARRANGEMENT OCCUPANCY DETECTION

GM GLOBAL TECHNOLOGY OPER...

1. A motor vehicle seat arrangement comprising:at least one seat having a seat cushion with a seating surface and a lower side facing away from the seating surface; and
a measurement arrangement including
a carrier fastened to a structural body element of a vehicle body, the carrier being formed by plastic and having a first modulus of elasticity;
a support layer positioned on the carrier on a carrier side opposite the structural body element and being formed by an elastomer, the support layer having a second modulus of elasticity, the first modulus of elasticity being at least twice the second modulus of elasticity; and
at least one sensor formed as a foil-like measurement layer on the support layer on a support layer side opposite the carrier and configured to detect a loaded state of the seat cushion by detecting at least one of a deformation or a force loading of the lower side of the seat cushion.

US Pat. No. 10,166,936

DAMPING MATERIAL

Nishikawa Rubber Co., Ltd...

1. A damping material to be attached to a vibration-suppression-target member, the damping material comprising:a mass body containing section in which a hollow section is formed for containing a mass body; and
a gripping section for fixing the damping material to the vibration-suppression-target member by pinching the vibration-suppression-target member,
the mass body containing section and the gripping section each being made of an elastic material, and
the mass body being inserted into the hollow section.

US Pat. No. 10,166,934

CAPTURING DRIVING RISK BASED ON VEHICLE STATE AND AUTOMATIC DETECTION OF A STATE OF A LOCATION

Lytx, Inc., San Diego, C...

1. A system for capturing an event, comprising:an interface to receive a vehicle location based at least in part on a GPS data;
a processor to:
determine that a vehicle is approaching a location of interest based at least in part on the vehicle location;
determine an estimated image capture time for the location of interest, wherein determining the estimated image capture time is based at least in part on a driver profile;
capture an image of the location of interest at the estimated capture time;
determine a state of the location of interest; and
detect an event based at least in part on the state of the location of interest.

US Pat. No. 10,166,920

TRACTOR-TRAILER CONNECTIONS FOR IMAGE CAPTURE DATA

Trimble Navigation Limite...

1. A system for use on a vehicle comprising a tractor and a trailer, the system comprising:a transmitter unit configured for mounting at the trailer, the transmitter unit comprising:
a video input configured to receive video data from one or more cameras mounted at the trailer, at least one of the one or more cameras spaced away from the transmitter unit;
a power input configured to receive power from a power line of the trailer;
a wireless communication module configured to communicate with a hand-held mobile communication device via a short range wireless communication link, the hand-held mobile communication device comprising a tablet or a smartphone;
a memory of the transmitter unit configured to store trailer information received from the hand-held mobile communication device via the wireless communication module, the trailer information comprising at least trailer ID data that uniquely identifies the trailer; and
a transmitter configured to wirelessly transmit the video data;
a receiver unit configured for mounting at the tractor, the receiver unit comprising:
a receiver configured to wirelessly receive the video data transmitted by the transmitter;
a power input configured to receive power from a power line of the tractor; and
an output configured to output the received video data;
wherein the receiver unit is further configured to receive the trailer information from the transmitter unit;
a media recorder configured for mounting at the tractor, the media recorder coupled to the receiver and configured to store the video data received by the receiver;
an onboard computer configured for mounting at the tractor, wherein one of the media recorder and the onboard computer is configured to associate the trailer ID with the video data stored on the media recorder; and
an onboard communication device coupled to one or both of the media recorder and the onboard computer, wherein the onboard communication device is configured to transmit the video data and associated trailer ID to a remote system.

US Pat. No. 10,166,813

AXLE WHEEL END AXIAL THRUST ASSEMBLY

KOYO BEARINGS NORTH AMERI...

1. An axle assembly of vehicle, comprising: a differential assembly; a first axle tube extending outwardly from a first side of the differential assembly, the first axle tube including a proximal end adjacent the differential assembly, an opposite distal end, and an axle bore extending therebetween; a first axle shaft rotatably received in the first axle tube, the first axle shaft including a proximal end disposed in the differential assembly, an opposite distal end extending outwardly from the distal end of the first axle shaft, and an annular groove extending radially inwardly from an outer surface of the first axle shaft;a retaining nut axially fixed to the distal end of the first axle tube; and a snap ring received in the annular groove of the first axle shaft,
wherein the snap ring bears against the retaining nut, thereby preventing outward motion of the first axle shaft with respect to the first axle tube.

US Pat. No. 10,166,807

METHOD AND DEVICE FOR APPLYING PORTIONS OF A BACKLINING MATERIAL TO THE BACK OF A BOOK BLOCK

MUELLER MARTINI HOLDING A...

1. A device for applying portions of a backlining material to backs of book blocks, the device comprising:a conveying apparatus configured to transport the book blocks through a book production line in a conveying direction;
a single pasting apparatus configured to apply an adhesive over an entire back length of the backs of the book blocks;
at least one backlining station comprising at least one supply apparatus configured to supply the backlining material and at least one cutting apparatus configured to cut the portions of the backlining material to length in accordance with a thickness of the back of a respective one of the book blocks to be supplied with the backlining material;
a first conveying device disposed after the single pasting apparatus in the conveying direction and configured to apply at least a first portion of the backlining material; and
at least one second conveying device disposed after the first conveying device in the conveying direction and configured to apply at least a second portion to the backs of the book blocks such that, in each case, at least one of the portions overlaps another one of the portions,
wherein the single pasting apparatus is the only pasting apparatus of the device.

US Pat. No. 10,166,796

TENSIONING DEVICE FOR PRINTER, UNWINDING DEVICE FOR PRINTER, AND PRINTER

BIXOLON CO., LTD., Seong...

1. An unwinding device for unwinding a sheet from a sheet roll disposed in a printer, and the sheet roll being inserted onto the device, the device comprising:a shaft;
a first rotating member and a second rotating member into which the shaft is inserted, configured to be rotatable with rotation of the sheet roll, the sheet roll being inserted onto the first rotating member and the second rotating member;
a first elastic member disposed between the first rotating member and the shaft, the first elastic member being configured to provide first back tension to the sheet when the first rotating member rotates;
a second elastic member disposed between the second rotating member and the shaft, the second elastic member being configured to provide second back tension to the sheet when the second rotating member rotates; and
a back tension controlling member disposed between the second elastic member and the shaft,
wherein the second back tension is not provided when the back tension controlling member is located in a first position, and
wherein the second back tension is provided when the back tension controlling member is located in a second position.

US Pat. No. 10,166,785

DIRECT PRINTABLE RIGID SUBSTRATE FOR INKJET PRINTING

Charta Group, Inc

1. A system for imprinting artwork and photography, consisting of:a rigid substrate having a surface, the rigid substrate selected from the group consisting of: metal and wood; and
an ink receptive layer coating the surface of the rigid substrate, the ink receptive layer having a thickness from about 0.005 mm to about 1 mm of:
(i) dispersing pigment selected from the group consisting of: aluminum oxide, silicon oxide, calcium carbonate, titanium oxide, and combinations of these;
(ii) binder selected from the group consisting of: poly-vinyl ethanol (PVOH), ethyl vinyl acetate (EVA), poly-urethane dispersion (PUD), latex polymer, and combinations of these; and
an inkjet print onto the ink receptive layer forming a high quality artwork image.

US Pat. No. 10,166,769

INKJET PRINTHEAD WITH MULTIPLE ALIGNED DROP EJECTORS

RF Printing Technologies ...

1. An inkjet printhead comprising:a two-dimensional array of drop ejectors arranged as a plurality of columns, each column including a plurality of banks, and each bank including a plurality of groups that each include a plurality of drop ejectors, wherein all of the drop ejectors in each bank are members of the plurality of groups in that bank, wherein the drop ejectors in each group are substantially aligned along a first direction, wherein the groups in each bank are spaced from each other along the first direction and are offset from each other along a second direction, wherein the banks in each column are spaced from each other along the first direction and are offset from each other along the second direction, wherein the columns are offset from each other along the second direction, wherein the two-dimensional array has a width W along the first direction and a length L greater than W along the second direction, and wherein each drop ejector in the two-dimensional array includes:
a nozzle;
an ink inlet that is configured to be in fluidic communication with a first ink source;
a pressure chamber in fluidic communication with the nozzle and the ink inlet; and
an actuator configured to selectively pressurize the pressure chamber for ejecting ink through the nozzle.

US Pat. No. 10,166,745

REMOVABLE FOAM TRACTION MAT

Marine Mat, Inc., Oldsma...

1. A removable cross-linked-closed-cell foam traction mat comprising:a layer of a cross-linked-closed-cell foam having an upper foam surface a lower foam surface, a foam weight, and a foam thickness;
a layer of a synthetic woven textile fiber having an upper fiber surface, a lower fiber surface, a fiber weight, a fiber thickness, a tensile strength, and a tongue tear strength, the upper fiber surface of the layer of synthetic woven textile fiber bonded to the lower foam surface of the cross-linked-closed-cell foam;
a layer of a non-skid base compound having an upper base compound surface, a lower base compound surface, a base compound weight, and a base compound thickness, the upper base compound surface of the layer of non-skid base compound bonded to the lower fiber surface of the layer of synthetic woven textile fiber, thereby forming a multi-layered structure having a structure weight and a kinetic coefficient of friction; and
a plurality of snaps, imbedded or otherwise incorporated into the multi-layered structure so as to allow the mat to be clasped and fastened to a desired location.

US Pat. No. 10,166,738

FLYING SPLICE TAPE WITH RESIDUE-FREE FASTENER FOR WOVEN AND NONWOVEN FIBROUS MATERIALS

TESA SE, Norderstedt (DE...

1. A method of providing a flying splice on a fibrous material, the method comprising:providing an adhesive tape comprising:
an adhesive layer,
a backing adjacent to the adhesive layer, and
a non-adhesive mechanical fastener;
contacting the adhesive layer to a leading edge of a top winding of a first roll of the fibrous material;
fastening the non-adhesive mechanical fastener to a second from the top winding of the first roll of the fibrous material;
contacting the adhesive layer with an unwinding second roll of the fibrous material without stopping or slowing the unwinding of the second roll of the fibrous material; and
releasing the non-adhesive mechanical fastener from the second from the top winding of the first roll of the fibrous material; wherein the released non-adhesive mechanical fastener does not leave a residue on the second from the top winding of the first roll of the fibrous material.

US Pat. No. 10,166,723

METHOD OF EDGE SEALING FOR SECONDARY LITHIUM BATTERY

NINGDE AMPEREX TECHNOLOGY...

1. A method of edge sealing for a secondary lithium battery, comprising steps of:a) prior to edge sealing, drawing a 3D model of a battery edge of a secondary lithium battery, and inputting the 3D model into a 3D printer;
b) prior to edge sealing, positioning the secondary lithium battery in a 3D printing area, and fixing a relative position of the secondary lithium battery in the 3D printing area;
c) stimulating, by the 3D printer, the battery edge according to the 3D model and setting a printing path;
d) adding edge sealing glue in a printing head of the 3D printer, the printing head moves according to the set printing path and in the meantime performs at least one time of printing, so that printed edge sealing glue covers the battery edge;
e) solidifying the edge sealing glue,
wherein, after accomplishing step e), further comprises coating edge folding glue on the battery edge coated with the solidified edge sealing glue, and performing single edge folding when the edge folding glue is half solidified, then fully solidifying the edge folding glue,
wherein, the edge folding glue is anaerobic glue, and
wherein, the anaerobic glue is tetraethylene glycol dimethacrylate anaerobic glue or hydroxyethyl methylacrylate anaerobic glue.

US Pat. No. 10,166,715

METHOD AND DEVICE FOR APPLYING PROTECTIVE SHEETING OF POLYMER MATERIAL TO A PIPELINE

SAIPEM S.p.A., San Donat...

1. A pipeline protective sheeting application device comprising:a carriage rotatable about a pipeline extending along a longitudinal axis and including a cutback bounded at opposite axial ends by two end portions of respective protective coatings of a polymer material;
an extrusion die mounted on the carriage, wherein in use, the extrusion die simultaneously winds about the pipeline and extrudes a protective sheeting of polymer material wide enough to cover the cutback and the end portions;
a heat treating unit mounted on the carriage and including at least two heaters, wherein the at least two heaters are located between the extrusion die and the pipeline, and in use, said heat treating unit directs and confines heat onto the end portions to directly heat free faces of the end portions; and
a roller configured to compress the protective sheeting against the pipeline including the end portions.

US Pat. No. 10,166,714

ROLLER AND METHOD FOR COMPRESSING PROTECTIVE SHEETING OF POLYMER MATERIAL AROUND A PIPELINE

SAIPEM S.P.A., San Donat...

1. A pipeline protective sheeting compression roller comprising:a shaft configured to rotate about an axis of rotation;
at least one first tubular portion which extends about the shaft and is configured to rotate about the axis of rotation, wherein the at least one first tubular portion varies in elasticity along the axis of rotation such that when the at least one first tubular portion compresses a protective sheeting of polymer material around a cutback of a pipeline including a raised portion, part of the at least one first tubular portion deforms for the raised portion of the pipeline to not alter a thickness of the protective sheeting; and
a second tubular portion which is fitted about the first tubular portion and includes a plurality of cylindrical walls movable with respect to one another and arranged end to end along the axis of rotation.

US Pat. No. 10,166,710

APPARATUS AND METHOD FOR DETECTING A POSITION OF AN ACTUATOR PISTON

Synventive Molding Soluti...

1. An injection molding system for implementing a molding process, comprising:a mold having a plurality of gates and a plurality of nozzles which during an injection cycle feed fluid material(s) into a common cavity of the mold, each nozzle having an associated valve pin, driven by an associated actuator, for opening and closing a respective gate into the common cavity,
a control system that controls movement of the valve pins over the course of the injection cycle in accordance with a set of predetermined process parameters,
a position sensor associated with each valve pin for monitoring a plurality of actual pin positions with respect to the gate and generating an output signal indicative of the plurality of actual pin positions as the valve pin moves between gate closed and gate open positions,
wherein, during an injection cycle, the system feeds the fluid material(s) to the nozzles at one or more predetermined times, starting by opening the valve pin of a respective nozzle at an opening time and allowing the fluid material to flow into the common cavity and wherein the fluid material(s) injected from the various nozzles joins together to form a single molded part in the common cavity,
the control system being configured to receive and process the output signal from the associated position sensor to determine, from the plurality of actual pin positions, one or more actual process parameters including an actual pin opening time and an actual pin opening velocity,
a display receiving and displaying the plurality of actual pin positions and the one or more actual process parameters by which a human operator can track the plurality of actual pin positions and the one or more actual process parameters in real time during the injection cycle, including the actual pin opening time and the actual pin opening velocity.

US Pat. No. 10,166,709

ACTUATOR COOLING APPARATUS AND METHOD

SYNVENTIVE MOLDING SOLUTI...

1. An injection molding apparatus comprising a clamp plate, a heated manifold, an actuator, a mold and a cooling device that cools the actuator, wherein when assembled the clamp plate and the mold are interconnected and spaced apart from each other, the manifold is disposed between the clamp plate and the mold and the actuator is mounted in thermally conductive communication with the manifold,wherein the cooling device comprises:
a heat transmitter comprising a distal arm or member and a proximal base or member, the distal arm or member being mounted by a spring loadable interconnection or engagement to the proximal base or member, the distal arm or member being comprised of a thermally conductive material having a distal end surface for engaging the clamp plate under a spring load and a proximal surface in sliding contact with a surface of the actuator for transmitting heat from the proximal surface to the distal end surface,
one or more surfaces of the distal arm being slidably engaged with one or more surfaces of the proximal base, the proximal base transmitting heat to the distal arm via the slidably engaged surfaces,
the actuator comprising a housing body that is thermally conductive and mounted in thermal communication with the manifold,
the proximal base or member being mounted to the housing body of the actuator in an arrangement wherein the distal end surface of the movable rod or arm is movable through the spring loadable interconnection toward and away from the actuator,
the spring loadable interconnection comprising one or more rods or tubes slidably mounted via one or more springs to the proximal base or member 504 and interconnected to the distal arm or member transmitting heat from the proximal base or member to the distal arm or member,
the clamp plate, the mold, the manifold, the actuator and the heat transmitter being assemblable together in an arrangement wherein the spring loadable interconnection is loaded urging the distal end surface of the movable rod or arm into compressed engagement with the clamp plate at least when the manifold is heated to an elevated operating temperature.

US Pat. No. 10,166,702

DEVICE AND METHOD FOR THE MANUFACTURING OF A SUPPORT FOR THE HUMAN BODY

SELLE ROYAL S.P.A., Pozz...

10. A process for manufacturing a support for the human body, wherein it comprises the steps of:providing a mould comprising a lower female portion and an upper male portion capable of being coupled with one another so as to define, between them, at least one cavity inside which at least one material in the fluid state, intended to make the support, can be poured, wherein said lower female portion of the mould has a lower through opening;
providing at least one mobile block for said female portion comprising at least two different surfaces, each surface configured to selectively close said at least one cavity at the lower through opening of said lower female portion of the mould for making respective different bottoms of said cavity during separate pouring steps of said at least one material;
positioning said at least one mobile block with a first surface at said cavity, said first surface being suitable for making up a respective first bottom for a first pouring step of said at least one material;
carrying out a first pouring step of said at least one material inside said cavity;
positioning said at least one mobile block with a second surface at said cavity, said second surface being suitable for making up a respective second bottom for a second pouring step of said at least one material;
carrying out a second pouring step of said at least one material inside said cavity; and
closing said male portion of the mould.

US Pat. No. 10,166,698

CRUSHING MILL FOR CRUSHING FIBROUS MATERIAL AND A UNIT FOR FORMING ABSORBENT CORES IN A MACHINE WHICH MAKES ABSORBENT SANITARY ARTICLES

GDM S.P.A., Bologna (IT)...

14. A crushing mill for crushing fibrous material for a unit for forming absorbent cores in a machine which makes absorbent sanitary articles, comprising:a casing including an infeed opening and an outfeed opening for fibrous material;
a rotor rotatable about an axis of rotation thereof and housed in the casing at an intermediate position between the infeed opening and the outfeed opening;
an auxiliary opening operatively interposed between the infeed opening and the outfeed opening, with reference to a direction of rotation of the rotor, and adapted to allow feeding particulate absorbent material into an intermediate zone between the infeed opening and the outfeed opening;
a diffuser member, the diffuser member including an infeed portion for feeding in the particulate absorbent material and an outfeed portion for feeding out the particulate absorbent material, the diffuser member being located at the auxiliary opening of the casing and extending along a direction of extension between the infeed portion and the outfeed portion, wherein a width of the infeed portion, measured at right angles to the direction of extension is smaller than a corresponding width of the outfeed portion.

US Pat. No. 10,166,688

METHOD FOR OBTAINING ONE OR A NUMBER OF STRIPS OF A BAND MATERIAL AND A CUTTING DIE FOR PUTTING THE METHOD INTO PRACTICE

Girnet Internacional, S.L...

1. A method for obtaining one strip (4) or a number of strips from a band material (1) which extends in a longitudinal direction (Y), comprising using a die carrier (8) and a cutting die (2) which has at least two cutting edges (3) of equal length which are repeatedly applied in consecutive cutting operations against longitudinally contiguous sections of the band and cooperate in order to cut two portions of band (1a) therebetween which are connected in order to form a continuous strip (4), there being at least two theoretic cutting start and end points (A, B) on each one of the cutting edges (3) which determine a predetermined cutting pattern between each other, wherein a cutting die (2) is used, the cutting edges (3) of which extend in at least one cutting line (7) beyond the theoretic cutting start point (A) or theoretic cutting end point (B), or in both, and said cutting lines (7) comprise a correcting section (7b) which extends in a direction that is not parallel to the cited longitudinal direction (Y), said correcting sections (7b) of the cutting lines (7) so as to compensate for a lateral discrepancy between the theoretic cutting start and end points (A) and (B) between two consecutive cutting operations.

US Pat. No. 10,166,659

RATCHET WRENCH

Powagrip Industrial Co. L...

1. A ratchet wrench comprising:a main body having an operating rod and a head portion, and a height of the head portion being slightly higher than the operating rod to form a stepped portion therebetween; an operating hole penetrating through a central portion of the head portion, and a ratchet gear, which is operated by a switching unit, installed inside the operating hole; a surface of the stepped portion having a slot which is horizontally extended toward and communicated with the operating hole, and after moved into the slot, a locating unit configured to extend toward an interior of the operating hole through an engaging portion thereof; an upper surface of the head portion, having a vertical connecting hole which is located close to a first lateral edge of the main body and communicated with the slot, and a bolt, which is positioned on an upper surface of the operating rod, located close to a second lateral edge of the main body;
the locating unit comprising a first end and a second end, and a pivotal hole formed on the first end, and an elongated slot, which is formed at a bottom portion of the locating unit, located close to the second end; the engaging portion located at an edge of the locating unit between the first end and the second end, and a height of the engaging portion being smaller than other portions of the locating unit;
at least an accessory tool installed in the ratchet gear of the main body, and by turning the operating rod, the accessory tool configured to be driven by the ratchet gear to achieve operation; a peripheral groove located at an end of the accessory tool along an outer periphery thereof; and
a spring positioned inside the elongated slot of the locating unit, and the pivotal hole of the locating unit aligned with the connecting hole of the main body to allow a locating piece to penetrate through both of the pivotal hole and the connecting hole such that the locating unit pivotally connected on the main body and the engaging portion of the locating unit positioned inside the slot; the bolt, which is positioned into the elongated slot, configured to bear against an end of the spring such that the spring, which bears against the locating unit at another end thereof, configured to allow the engaging portion of the locating unit to extend toward the interior of the operating hole, thereby engaging with the peripheral groove of the accessory tool, and the accessory tool configured to be secured on the operating hole of the main body when operation.

US Pat. No. 10,166,654

DENSE PACKING PARTICLE SIZE DISTRIBUTION FOR PDC CUTTERS

DIAMOND INNOVATIONS, INC....

1. A method of making a superabrasive compact, comprising:calculating a first metric value measuring a shift in the mean of a principle particle statistical distribution after mixing the principle particles with additional fine particles, the first metric value calculated as (d50)/(d50 principle particles) and equal to the mean of the distribution of a combination of principle particles mixed with additional fine particles (d50), divided by the mean of a distribution of principle particles (d50 principle particles), wherein the particles larger than d50 comprise a volume area A;
providing a support to the plurality of superabrasive particles; and
subjecting the support and the plurality of superabrasive particles to conditions of an elevated temperature and pressure suitable for producing the polycrystalline superabrasive compact, wherein the principle particles range in size from 1 micron to 100 microns.

US Pat. No. 10,166,644

PROCESSING INSPECTION WORKPIECE FOR MACHINE TOOL, AND ON-MACHINE MEASUREMENT METHOD USING SAID WORKPIECE

MITSUBISHI HEAVY INDUSTRI...

1. An on-machine measurement method using a processing inspection workpiece for a machine tool, the method comprising:Using the processing inspection workpiece which has at least one processing surface, and at least one reference surface facing in a direction in which the processing surface faces, and having a plurality of in-plane measurement points whose coordinates are known;
replacing an attachment of the machine tool with a measurement sensor configured to detect a contact position with the processing inspection workpiece, after the machine tool processes the processing inspection workpiece;
performing a first measurement to measure the measurement points on the reference surface by using the measurement sensor;
performing, after the first measurement, a second measurement to measure a measurement point on the processing surface near the measurement points on the reference surface by using the measurement sensor; and
detecting coordinates of all the measurement points by alternately performing the first measurement and the second measurement on all of the reference surface and the processing surface.

US Pat. No. 10,166,610

COMPENSATION CHUCK FOR CENTRICALLY CLAMPING WORKPIECES

HVM Technology GmbH, Oyt...

1. A compensation chuck for centrically clamping workpieces comprising:a housing,
two pairs of mutually diametrally opposite base jaws for receiving corresponding clamping jaws,
a drive unit which is moveable by power clamping having two pairs of drivable entrainment members, wherein two adjacent entrainment members are respectively coupled together by a first rocker and two further adjacent entrainment members are coupled together by a second rocker, and
a coupling ring which guides a first entrainment member and a diametrally opposite second entrainment member in the peripheral direction tangentially relative to a clamping axis (A), wherein a motion play is provided between the entrainment members and the coupling ring in the radial direction.

US Pat. No. 10,166,607

TETRAHEDRON-SHAPED CUTTING INSERT, INSERT HOLDER AND CUTTING TOOL

Iscar, Ltd., Tefen (IL)

1. A two-way indexable cutting insert (22) comprising:a regular tetrahedral basic shape defined by exactly four insert corner portions (30); and four insert face surfaces (32) mutually intersecting each other and comprising:
a first rake face surface (34a) and a first relief face surface (36a) that intersect to form a first major cutting edge (44a); and
a second rake face surface (34b) and a second relief face surface (36b) that intersect to form a second major cutting edge (44b) wherein:
each of the four insert face surfaces (32) has only one rake face surface (34a, 34b) or one relief face surface (36a, 36b), and none of the insert face surfaces has both a rake face surface (34a, 34b) and also a relief face surface (36a, 36b).

US Pat. No. 10,166,592

METHOD FOR FORMING A SHEET MADE OF AN ALUMINUM ALLOY INTO A COMPONENT OF COMPLEX SHAPE, PARTICULARLY A MOTOR-VEHICLE COMPONENT

C.R.F. Societa Consortile...

1. A method for forming a sheet made of an aluminium alloy into a component of complex shape, which comprises the following steps:providing a mould for blow-forming said sheet made of aluminium alloy with an aid of pressurized forming gas,
heating said sheet made of aluminium alloy and/or said mould to a predetermined heating temperature,
arranging, in a forming stage, the sheet within the mould, closing the mould and introducing pressurized forming gas into a chamber of the mould with a first face of the sheet facing this chamber, so that the sheet is pushed against a surface of the mould towards which a second face of the sheet is facing,
removing the sheet formed thereby from the mould and subjecting the sheet to a heat treatment,
said method being characterized in that:
the alloy constituting said sheet does not have superplasticity features,
said predetermined heating temperature is in the order of 400°-550° C.,
a maximum pressure reached by the forming gas is in the order of 20-30 bars, and
a time for forming the sheet within the mould is between 40 and 150 seconds,
wherein in a first part of the forming stage, the pressurized forming gas is fed into said chamber of the mould while clamping peripheral portions of the sheet between clamping surfaces of upper and lower elements of the mould with a force sufficient for ensuring sealing against pressurized gas in the mould, but not so high as to prevent a sliding movement of said peripheral portions with respect to said clamping surfaces the mould, parallel to said clamping surfaces, so that said peripheral portions slide relative to said clamping surfaces during said first part of the forming step, thereby enabling a first forming of the sheet without elongation thereof, and thereafter, in a second part of the forming stage, this sliding is prevented and the pressurized forming gas is kept to be fed into said chamber, so as to press the sheet against a wall of the mould, thus causing an elongation of the sheet until it reaches its final shape.

US Pat. No. 10,166,567

COATING APPARATUS AND METHOD OF COATING JOINT

Aegion Coating Services, ...

1. A coating apparatus for coating a perimeter surface of a pipeline, the coating apparatus comprising:a mounting frame configured to be selectively mounted on the pipeline;
a sprayer mounted on the mounting frame and configured to deliver a fluid along a flow path oriented toward the perimeter surface of the pipeline when the mounting frame is mounted on the pipeline, the sprayer being operable in at least one operational mode to deliver curable liquid along the flow path in a spray pattern, the coating apparatus being configured to move the sprayer circumferentially around the pipeline when the sprayer is operating in said at least one operational mode to coat the perimeter surface with the curable liquid;
a vacuum system operable to impart a vacuum pressure on a space adjacent the flow path to draw a divertible fluid delivered from the sprayer away from said space; and
an overspray shroud comprising a wall defining a shroud interior and having a sprayer opening and a vacuum opening formed therein, the overspray shroud and the sprayer being fixed in position relative one another such that the sprayer is oriented to deliver fluid along the flow path through the sprayer opening and the shroud interior, the vacuum system being operatively connected to the vacuum opening to draw the divertible fluid away from the shroud interior as the sprayer is operated to coat the perimeter surface with the curable liquid;
wherein the vacuum opening is spaced apart from the flow path.

US Pat. No. 10,166,546

REDUCED MASS PLATES FOR REFINERS AND DISPERSERS

Andritz Inc., Glens Fall...

1. A plate segment configured to be mounted on a disc of a disperser or refiner of comminuted cellulosic material, the plate segment comprising:a front face including disperser teeth or refining bars;
a back face opposing the front face, the back face including a raised post surrounding a hole configured to receive a fastener a raised plate positioning section;
lateral sides extending between the front face and the back face; and
a radially outer side and a radially inner side extending between the lateral sides, wherein the radially inner side comprises a contact edge;
wherein the back face lacks raised structures along the lateral aides,
wherein the raised post and raised plate positioning section each have contact surfaces, wherein the contact surfaces and the contact edge are aligned in a common contact plane, and wherein the back face is not configured to abut a disc of a disperser or a refiner of comminuted cellulosic material.

US Pat. No. 10,166,518

MULTI-HEATER METHOD FOR GROWING HIGH QUALITY DIAMOND

SUNSET PEAK INTERNATIONAL...

1. A method of growing a diamond in a reaction cell containing a carbon source, a solvent metal, and a diamond seed crystal, the method comprising:preparing a high temperature, high pressure (HTHP) apparatus to enclose a reaction cell and subjecting the reaction cell to an isostatic pressure ranging from 5 to 7.5 GPa and a temperature ranging from 1200 to 1700 degree C.;
surrounding the reaction cell with a main heater, a first sub-heater and a second sub-heater, with the first sub-heater located at a top end of the main heater and the second sub-heater located at a bottom end of the main heater, with the main heater, first sub-heater and second sub-heater being powered from a first power supply;
surrounding the main heater, the first sub-heater and the second sub-heater with heat insulators;
controlling the main heater, the first sub-heater and the second sub-heater to melt the solvent metal and to create a predetermined temperature gradient from a high near the carbon source to a low at the diamond seed crystal;
allowing both the carbon source to dissolve in the molten solvent metal and the diamond seed crystal to grow to an initiation size for a predetermined time period;
controlling a second independent heater, which is configured as a ring heater disposed around the reaction cell to adjust the predetermined temperature gradient after elapsed of the predetermined time period, with the ring heater being powered from a second power supply; and
allowing the dissolved carbon in the molten solvent metal to deposit on the diamond seed crystal to obtain diamond at a controllable growth rate and with a controllable amount of inclusions.

US Pat. No. 10,166,517

PROCESS AND APPARATUS FOR PRODUCTION OF A GRANULAR UREA PRODUCT

Casale SA, Lugano (CH)

7. Equipment for carrying out a process according to claim 1, comprising at least:a first environment;
means adapted to feed at least a first flow of droplets of fresh urea melt and cooling air to said first environment, to cause the formation of solid starting particles,
means to feed at least a second flow of larger droplets of urea melt to said first environment, the droplets of said second flow being larger than droplets of said first flow,
a second environment in communication with the first environment and means for feeding particles formed in the first environment and droplets of urea and fluidizing air to said second environment for granulation of said solid particles under a fluidized-bed state;
wherein the means feeding said first flow of droplets being adapted to deliver droplets with a diameter equal to or less than 200 ?m.

US Pat. No. 10,166,513

SPACER FOR A MEMBRANE MODULE

NANYANG TECHNOLOGICAL UNI...

1. A spacer for a membrane module, the spacer comprising:a plurality of first filaments defining a plurality of fluid flow channels, in use the plurality of fluid flow channels being adjacent a membrane of the membrane module; and
a plurality of second filaments provided on the plurality of first filaments and extending into the fluid flow channels, the second filaments moveable relative to the first filaments in response to an external stimulus during flow of fluid in the fluid flow channels.

US Pat. No. 10,166,506

HYDROGEN GENERATION ASSEMBLIES AND HYDROGEN PURIFICATION DEVICES

Element 1 Corp., Bend, O...

1. A hydrogen purification device, comprising:first and second end frames including:
an input port configured to receive a mixed gas stream containing hydrogen gas and other gases;
an output port configured to receive a permeate stream containing at least one of a greater concentration of hydrogen gas and a lower concentration of the other gases than the mixed gas stream; and
a byproduct port configured to receive a byproduct stream containing at least a substantial portion of the other gases;
at least one hydrogen-selective membrane disposed between and secured to the first and second end frames, the at least one hydrogen-selective membrane having a feed side and a permeate side, at least part of the permeate stream being formed from the portion of the mixed gas stream that passes from the feed side to the permeate side, with the remaining portion of the mixed gas stream, which remains on the feed side, forming at least part of the byproduct stream;
at least one microscreen structure configured to support the at least one hydrogen-selective membrane; and
a plurality of frames disposed between the first and second end frames and the at least one hydrogen-selective membrane and secured to the first and second end frames, wherein each frame of the plurality of frames includes a perimeter shell defining an open region, the plurality of frames including at least one permeate frame disposed between the at least one hydrogen-selective membrane and the second end frame, the at least one permeate frame further includes:
an output conduit formed on the perimeter shell and configured to receive the at least part of the permeate stream from the at least one hydrogen-selective membrane, and
at least one membrane support structure that spans at least a substantial portion of the open region of the at least one permeate frame and that is configured to support the at least one microscreen structure, the at least one membrane support structure being free from perforations,
wherein the at least one microscreen structure is disposed between the at least one hydrogen-selective membrane and the at least one permeate frame, wherein the at least one microscreen structure includes generally opposed surfaces configured to provide support to the permeate side, and a plurality of fluid passages extending between the opposed surfaces, and wherein the at least one microscreen structure is not fitted within an open region of a frame of the plurality of frames.

US Pat. No. 10,166,501

GAS GENERATOR

DAICEL CORPORATION, Osak...

1. A gas generator comprising a housing foamed by a diffuser shell provided with a gas discharge port, and a closure shell, a cylindrical filter disposed inside the housing, a first combustion chamber and a second combustion chamber arranged inside the cylindrical filter,the cylindrical filter being disposed such that an outer circumferential surface is spaced apart from the gas discharge port, a first annular end surface is abutted against a top plate of the diffuser shell, and a second annular end surface is abutted against a bottom plate of the closure shell,
the first combustion chamber being a space on the outer side of an ignition device chamber provided with an ignition device for a first-b gas generating agent filled inside the first combustion chamber, and the second combustion chamber being filled with a second gas generating agent,
the ignition device chamber being a space filled with a first-a gas generating agent and surrounded by a cylindrical first holder, a first igniter and a first cup member provided with a plurality of first communication holes penetrating a circumference wall thereof in a thickness direction,
the cylindrical first holder being fixed to a first hole of the bottom plate of the closure shell, the first igniter being fixed inside the cylindrical first holder, and the first cup member being press-fitted to an inner side of the cylindrical first holder from an opening of the first cup member,
the second combustion chamber being a space filled with the second gas generating agent and surrounded by a cylindrical second holder, a second igniter and a second cup member provided with a plurality of second communication holes penetrating a circumferential wall thereof in a thickness direction,
the cylindrical second holder being fixed to a second hole of the bottom plate of the closure shell, the second igniter being fixed inside the cylindrical second holder, the second cup member being press-fitted to an outer side of the cylindrical second holder from an opening of the second cup member, and a surface of the circumferential wall including the plurality of the second communication holes being covered with a cover member from the outside,
further, a support member for the cylindrical filter being disposed on a bottom surface of the closure shell,
the support member including a bottom surface provided with holes corresponding to the first hole and the second hole formed in a bottom plate of the closure shell, and an outer circumferential wall provided vertically from an outer circumference of the bottom surface,
part of the outer circumferential wall of the support member being held from both sides in a thickness direction between the first holder and the cylindrical filter,
the bottom surface of the support member being held from both sides in a thickness direction between the bottom plate of the closure shell and an annular end surface of the opening of the second cup member press-fitted to the cylindrical second holder,
the outer circumferential wall of the support member being abutted against an inner circumferential surface of the cylindrical filter on the side of the second annular end surface so that a corner portion formed by the bottom surface and the outer circumferential wall of the support member is abutted against an abutting portion between the second annular end surface of the cylindrical filter and the bottom plate of the closure shell,
when the second igniter is actuated and the second gas generating agent in the second combustion chamber is ignited and burned to raise an internal pressure, a combustion gas flowing out between the second communication holes and the cover member in a direction of the bottom plate of the closure shell.

US Pat. No. 10,166,497

PLUNGER PUMPING ARRANGEMENT FOR A HOLLOW FIBER FILTER

Repligen Corporation, Wa...

23. A fluid filtration system, comprising:first and second process vessels;
a first filter housing having a first end in fluid communication with the first process vessel;
a second filter housing having a first end in fluid communication with the second process vessel;
a first plunger pump coupled to a second end of the first filter housing;
a second plunger pump coupled to a second end of the second filter housing;
a first actuator having a first movable plunger;
a second actuator having a second movable plunger;
wherein the first plunger pump includes a housing having a rigid portion and a flexible portion, the flexible portion having a plunger-engaging portion for coupling to the first movable plunger of the first actuator, the flexible portion being selectively deformable so that the flexible portion moves with respect to the rigid portion in response to movement of the first movable plunger by the first actuator, deformation of the flexible portion generating reciprocating vacuum and pressure to move fluid between the first plunger pump and the first process vessel;
wherein the second plunger pump includes a housing having a rigid portion and a flexible portion, the flexible portion having a plunger-engaging portion for coupling to the second movable plunger of the second actuator, the flexible portion being selectively deformable so that the flexible portion moves with respect to the rigid portion in response to movement of the second movable plunger by the second actuator, deformation of the flexible portion generating reciprocating vacuum and pressure to move fluid between the second plunger pump and the second process vessel; and
a controller in communication with the actuator for simultaneously actuating the first and second plunger pumps to cycle fluid between the first and second plunger pumps and the first and second process vessels.

US Pat. No. 10,166,492

BUBBLE REMOVING UNIT AND SUBSTRATE TREATING APPARATUS INCLUDING THE SAME

Semes Co., Ltd., Chungch...

1. A bubble removing unit comprising:a body having an inner space, through which a liquid can flow;
a liquid introducing pipe through which the liquid can be supplied to the body;
a liquid discharging pipe through which the liquid, from which bubbles are removed, can be discharged from the body;
a bubble discharging pipe through which the bubbles can be discharged from the inner space; and
a rod-shaped bar situated in the inner space and a length of which extends in a lengthwise direction of the body,
wherein a variable cross-section part situated between the liquid introducing pipe and the liquid discharging pipe and a cross-section of which varies along the lengthwise direction of the body is provided in the inner space of the body; and
wherein the bar has a spiral groove on an outer surface thereof in contact with the liquid.

US Pat. No. 10,166,464

PUZZLE

AGATSUMA CO., LTD., Toky...

1. A puzzle comprising:a housing main body;
three puzzle shafts secured relative to the housing main body, wherein each of the three puzzle shafts is fixed so as not to rotate around a shaft center thereof,
a plurality of pieces rotatably mounted on each of the three puzzle shafts so as to rotate around the shaft center, wherein puzzle patterns are provided on an outer periphery of each of the plurality of pieces, wherein each of the plurality of pieces includes a ratchet pawl; and
a ratchet mechanism configured with ratchet teeth formed on an outer periphery of each of the three puzzle shafts, wherein the ratchet pawl on each of the plurality of pieces is elastically configured to engage the ratchet teeth,
wherein the housing main body has two moving member main bodies disposed alongside the shafts used as right and left grip parts which are connected respectively to each of two outer puzzle shafts of the three puzzle shafts so as to move the two outer puzzle shafts in an outer direction orthogonal to a longitudinal extent of the three puzzle shafts,
wherein each of the two moving member main bodies is formed substantially with a shell shape, has a back face side that is hollow, and a front face side with finger-hooking recesses.

US Pat. No. 10,166,410

FOCUSED ULTRASOUND GUIDING SYSTEM AND METHOD THEREOF

CHANG GUNG UNIVERSITY, T...

1. An ultrasound system, which guides a focused ultrasound energy to a target point located in a tissue of a central nervous system, comprising:a focused ultrasound device generating a focus point and delivering said energy to said target point which is a tissue wrapped by a hard tissue, and said target point is located in an interested region of an individual;
a first tracking point, a second tracking point and a computer unit, wherein said first tracking point provides fixed reference coordinates and is arranged at a location whose relative position to said interested region of said individual is invariable, and wherein said second tracking point is arranged on an ultrasonic transducer of said focused ultrasound device, and said computer unit retrieves an image of said interested region of said individual, and said image of said interested region of said individual is a previously obtained image obtained with an MRI (Magnetic Resonance Imaging) technology or a CT (Computed Tomography) technology;
reference points on said interested region with spatial positions, and wherein said computer unit records said reference points on said interested region to determine coordinates of said reference points in said image of said interested region;
a calibration tracker connecting with said computer unit;
a dummy arranged on said ultrasonic transducer, wherein said dummy includes a tip pointing out a spatial position of said focus point, and said tip of said dummy, said second tracking point and said first tracking point are tracked by said calibration tracker and said computer unit to search said spatial position of said, focus point and said computer unit compares said spatial positions of said first tracking point, said second tracking point and said reference points with said coordinates of said first tracking point, said second tracking point and said reference points in said image of said interested region to establish the positional relationship between said first tracking point, said second tracking point and said reference points in said image of said interested region, whereby said spatial position of said focus point corresponds to coordinates of said focus point in said image of said interested region based on known positional relationship between said second tracking point and said focus point; and
a fixture fixing said interested region of said individual.

US Pat. No. 10,166,393

ACTIVE IMPLANTABLE MEDICAL DEVICE FOR HEART FAILURE TREATMENT BY STIMULATION OF THE VAGUS NERVE

SORIN CRM SAS, Clamart (...

1. An active implantable medical device for the treatment of heart failure by stimulation of a vagus nerve (VNS) or one of its branches, comprising:a VNS pulse generator and an electrode adapted to be placed on or close to the vagus nerve of a patient;
an activity sensor capable of delivering successive values of the patient's current activity level; and
a processor configured to:
collect the electrical activity of the heart, the electrical activity used to determine successive values of a current intrinsic heart rate of the patient;
calculate successive values of a reference heart rate based on the respective successive values of the patient's current activity level, wherein calculating the successive values of the reference heart rate comprises filtering the values of the calculated reference heart rate, by application of a time constant;
construct a first histogram from the reference heart rate depending on the respective values of the patient's current activity level delivered by the activity sensor, over a predefined monitoring period;
construct a second histogram, distinct from the first histogram, from the intrinsic heart rate values over the predefined monitoring period; and
derive an index representative of the patient's condition at the end of the predefined monitoring period, by comparing the first and second histograms.

US Pat. No. 10,166,371

NON-COMPLIANT MULTILAYERED BALLOON FOR A CATHETER

ABBOTT CARDIOVASCULAR SYS...

1. A method of making a multilayer balloon for a catheter comprising:selecting a first polymer material having a first maximum blow-up-ratio;
selecting a second polymer material having a second maximum blow-up-ratio greater than the first maximum blow-up-ratio;
selecting a third polymer material having a third maximum blow-up-ratio greater than the second maximum blow-up-ratio; and
forming a multilayer balloon having at least a first layer of the first polymer material, a second layer of the second polymeric material, and a third layer of the third polymeric material having a combined wall thickness, wherein the second layer is an inner layer relative to the first layer and the third layer is an inner layer relative to the second layer, and wherein the at least first, second, and third layers define a compliance less than that of a single layer balloon made of the first polymer material with a wall thickness equal to the combined wall thickness.

US Pat. No. 10,166,359

CONNECTOR FOR RESPIRATORY DUCTS

Intersurgical AG, Vaduz ...

1. A connector for connecting respiratory ducts together such that they are placed in fluid communication, the connector comprising:a first conduit having a female connector end; and
a second conduit having a male connector end adapted to be received within the female connector end of the first conduit such that the male and female connector ends overlap to provide a common conduit having an inner surface formed at least in part by the male connector end,
wherein the male connector end has a retaining formation which is adapted to abut a corresponding engagement formation on an overlapping portion of the female connector end so as to resist separation of the first and second conduits whilst permitting relative rotation thereof when connected,
and wherein the engagement formation comprises an annular recess on an inner surface of the female connector end shaped to accommodate the retaining formation with a close fit, and the inner surface of the overlapping portion of the female connector end comprises a plurality of depressions and raised portions in the regions between the depressions, the plurality of depressions and raised portions extending in a direction substantially parallel with an axis of the first conduit, the depressions leading into the annular recess.

US Pat. No. 10,166,336

AUTO-INJECTOR FOR RETRACTABLE PREFILLED SYRINGE

UNL Holdings LLC, New Yo...

1. An actuation mechanism for an automatic injector, comprising: a first actuation spring, a first actuation pill, a second actuation spring arranged distal to and coaxially with the first actuation spring and a second actuation pill, wherein in an initial configuration the first actuation spring resides in a compressed, energized state substantially within an upper portion of the first actuation pill, and the second actuation spring resides in a compressed, energized state between the first actuation pill and the second actuation pill, and the first actuation pill and the second actuation pill are detachably, directly connected to prevent relative movement between the first actuation pill and the second actuation pill and to maintain the second actuation spring in the compressed, energized state between the first actuation pill and the second actuation pill.

US Pat. No. 10,166,334

MEDICINE INJECTION APPARATUSES

Washington Biotech Corpor...

1. An apparatus forming a medicine injector, comprising:a barrel;
a receiving cavity within the barrel, the receiving cavity configured to receive a medicine ampule and needle assembly with an injection needle capable of being projected from the barrel to perform an injection;
a driver configured to operate within the barrel, the driver configured to move the needle into an injection position and dispense a medicine from the medicine ampule; and
a penetration controller configured to achieve a desired needle penetration depth when engaging the medicine ampule and needle assembly, the penetration controller comprising:
a control sleeve having flange lobes;
a spring located radially adjacent the control sleeve, wherein the control sleeve resides between the barrel and the spring in one cross section, and the spring includes at least one winding engaging the flange lobes; and
a cushion ring between the driver and the control sleeve.

US Pat. No. 10,166,332

APPARATUS TO INJECT FLUIDS INTO BONE MARROW AND OTHER TARGET SITES

1. An apparatus for delivering a quantity of fluid to bone marrow comprising:a drive housing comprising a first portion configured to engage a driver assembly and a second portion configured to engage a cartridge assembly, the drive housing configured to receive a rotational force from the driver assembly and to transmit the rotational force to the cartridge assembly, the cartridge assembly comprising a fluid reservoir and a plunger assembly slidably disposed in the fluid reservoir, the cartridge assembly engaged with a bone penetrating needle and configured to rotate to insert the bone penetrating needle into the bone marrow;
a plunger operating assembly configured to receive a portion of the plunger assembly of the cartridge assembly;
a retractable sleeve configured to displace longitudinally relative to the drive housing and the plunger operating assembly, the retractable sleeve configured to move from a first position to a second position;
a first spring configured to bias the retractable sleeve in the first position;
a second spring configured to move the plunger operating assembly such that the plunger operating assembly moves the plunger assembly of the cartridge assembly to deliver the quantity of fluid to the bone marrow;
a first release mechanism configured to release the second spring to move the plunger operating assembly; and
a second release mechanism configured to release the engagement between the second portion of the drive housing and the cartridge assembly when the quantity of fluid is delivered to the bone marrow,
wherein the first release mechanism releases the second spring to move the plunger operating assembly when the cartridge assembly is rotated to insert the bone penetrating needle into the bone marrow and the retractable sleeve is moved to its second position.

US Pat. No. 10,166,329

PATCH-SIZED FLUID DELIVERY SYSTEMS AND METHODS

DEKA Products Limited Par...

15. A method of making a delivery device, the method comprising:providing a first housing portion;
providing a second housing portion comprising providing a housing structure with an internal volume configured to selectively engage with and disengage from the first housing portion;
supporting a rotatable rotor for rotation comprising supporting the rotatable rotor on the second housing portion outside of the internal volume, the rotor having at least one pad or roller for movement in an annular path with the rotation of the rotor;
providing a conduit having a flexible portion;
coupling an interior volume of a reservoir in fluid flow communication with the conduit, the interior volume of the reservoir for containing a fluid;
supporting the flexible portion of the conduit on the first housing portion and arranging the flexible portion of the conduit within at least a portion of the annular path of the at least one pad or roller to be engaged at locations along the annular path by the at least one pad or roller when the second housing portion and the first housing portion are engaged, the flexible portion of the conduit being resiliency collapsible at the locations of engagement of the at least one pad or roller to provide a pumping action as the rotor rotates while the first and second housing portions are engaged, the conduit being connectable in fluid flow communication with an injection site;
supporting a drive device on the second housing portion; and
operatively coupling the drive device to the rotor for selectively rotating the rotor to provide the pumping action while the first and second housing portions are engaged comprising extending a rotor shaft having a longitudinal axis into the interior volume of the second housing portion, operatively coupling the rotor shaft to the rotor and to the drive device to transfer drive force from the drive device to the rotor.

US Pat. No. 10,166,328

INFUSION SYSTEM WHICH UTILIZES ONE OR MORE SENSORS AND ADDITIONAL INFORMATION TO MAKE AN AIR DETERMINATION REGARDING THE INFUSION SYSTEM

ICU Medical, Inc., San C...

1. An infusion system configured to be connected to a fluid delivery line and to an infusion container containing an infusion fluid, the infusion system comprising:a pump for pumping infusion fluid from the infusion container;
at least one force sensor connected to the pump or the fluid delivery line, the at least one force sensor configured to measure force on a plunger of the pump;
at least one processor in electronic communication with the pump and the at least one force sensor;
a memory in electronic communication with the at least one processor, the memory comprising programming code for execution by the at least one processor; and
wherein the programming code is configured to cause the at least one processor to:
estimate future derived force measurement based on an application of a Kalman filter on the measured force on the plunger, wherein the estimation of future derived force measurement comprises at least one of:
determine a mean force measurement based on the measured force;
determine a variance force measurement based on the measured force; and
determine a derivative force measurement based on the measured force;
calculate a residual between the future derived force measurement and the measured force;
construct a cumulative sum control chart based on the calculated residual; and
determine air in the fluid delivery line based on the cumulative sum control chart and volume of infusion fluid pumped from the infusion container.

US Pat. No. 10,166,326

DEVICES, SYSTEMS AND METHODS FOR DETERMINING PARAMETERS OF ONE OR MORE PHASES OF AN INJECTION PROCEDURE

BAYER HEALTHCARE LLC, Wh...

1. A system for enabling delivery of fluid in an injection procedure to be performed on a patient in connection with a diagnostic imaging procedure, the system comprising:(a) a controller operably associated with at least one pressurizing mechanism though which at least one of a first fluid and a second fluid contained within at least one fluid container is injectable into the patient, the first fluid comprising a contrast enhancing agent and adapted to enhance contrast of images obtained during the diagnostic imaging procedure, the second fluid comprising a non-contrast enhancing fluid;
(b) the controller including a programming system for programming of an injection protocol comprising a plurality of phases to effect enhancement of at least one region of interest of the patient over a scan duration of the diagnostic imaging procedure, the plurality of phases comprising a first phase in which the first fluid is to be injected and a second phase in which an admixture of the non-contrast enhancing fluid with the first fluid is to be injected;
(c) a parameter generator inclusive of an algorithm associated with the programming system, the parameter generator for determining parameters of the injection protocol based in part upon a type of the injection procedure to be performed and the algorithm according to which at least a volume of the first phase, Vol1, and a volume of the second phase, Vol2, are determined using:
Vol1=durationscan×Q1 and
Vol2=((tscan_end?propagation delay)?duration1)×Q2
where durationscan is the scan duration, Q1 is a flow rate of the first phase; duration1 is a duration of the first phase, propagation delay is a delay in propagation of the contrast enhancing fluid from an injection site to the at least one region of interest, Q2 is a flow rate of the second phase, and tscan-end is computed using:
tscan-end=ttest-bolus-peak+durationscan
where ttest-bolus-peak is a time to peak enhancement that can be obtained from an injection of a test bolus of the contrast enhanced fluid into the patient; and
(d) the parameter generator is further characterized in that the algorithm enables computation of a ratio of the admixture based on at least a peak enhancement that occurs in the at least one region of interest as a result of the injection of the test bolus.

US Pat. No. 10,166,324

METHODS AND SYSTEM FOR TREATING ARTHRITIS

TERUMO KABUSHIKI KAISHA, ...

1. An arthritis treatment method comprising:a gel injection step of injecting a gel-like material toward a lesion area in which crystal-induced arthritis occurs, wherein the gel-like material covers the lesion area;
an instrument introducing step of causing at least one instrument having a tubular shape to communicate with the lesion area, wherein the instrument is inserted between the gel-like material and the lesion area; and
a treatment step of removing a causative agent of the crystal-induced arthritis from the lesion area by perfusion and discharge of a lavage fluid through the at least one instrument while the instrument is inserted between the gel-like material and the lesion area, and wherein the lavage fluid is prevented from spreading from the lesion area via the gel-like material covering the lesion area during the treatment step.

US Pat. No. 10,166,323

BLOOD SEPARATION BY MICROFLUIDIC ACOUSTIC FOCUSING

The Charles Stark Draper ...

1. A method of cleansing blood comprising:flowing whole blood, including plasma, a plurality of formed elements, and a plurality of undesirable particles, into an inlet of a microfluidic separation channel having a predetermined width and defined in a thermoplastic;
introducing a plurality of lipid-based capture particles into the whole blood such that the lipid-based capture particles bind to a plurality of the undesirable particles;
selecting a wavelength of a standing acoustic wave such that the predetermined width of the microfluidic separation channel is between 30% and 45% of the wavelength of the standing acoustic wave; and
applying the standing acoustic wave transverse to a direction of flow of the whole blood through the microfluidic separation channel such that the formed elements aggregate to about the axial center of the microfluidic separation channel and the capture particles aggregate along at least one wall of the microfluidic separation channel; and
cycling off the standing acoustic wave such that the duty cycle of the standing acoustic wave is between 75% and 95%.

US Pat. No. 10,166,321

HIGH-FLOW PORT AND INFUSION NEEDLE SYSTEMS

AngioDynamics, Inc., Lat...

1. A multi-reservoir port system, comprising:a vascular access port, including:
a housing defining first and second reservoirs,
a first septum mounted within the housing sealing the first reservoir, the first septum comprising an elastomeric material having a first septum first layer having a first durometer and a first septum second layer having a second durometer, the first septum second layer being encapsulated on all sides by the first septum first layer,
a second septum mounted within the housing sealing the second reservoir, the second septum comprising an elastomeric material having a second septum first layer having a first durometer and a second septum second layer having a second durometer, the second septum second layer being encapsulated on all sides by the second septum first layer,
an inlet stem having an inlet lumen in fluid communication with the first reservoir, and
an outlet stem having an outlet lumen in fluid communication with the second reservoir; and
a dual-lumen catheter having a proximal end, a distal end, and first and second lumens extending therebetween;
wherein the inlet stem is dimensioned to receive the first lumen at the proximal end of the catheter; and
wherein the outlet stem is dimensioned to receive the second lumen at the proximal end of the catheter.

US Pat. No. 10,166,316

CONTROLLED RANDOMIZED POROUS STRUCTURES AND METHODS FOR MAKING SAME

1. A method for fabricating a porous structure for a medical implant, the method comprising the steps of:creating a model of a porous structure, said creating step comprising causing a computing device to perform the steps of:
defining a first three dimensional space having an outer boundary and an inner volume,
placing a plurality of seed points for the first three dimensional space, wherein placing the plurality of seed points includes placing a plurality of outer seed points along the outer boundary, and placing a plurality of inner seed points in the inner volume,
moving at least one seed point from one of said plurality of outer seed points and said plurality of inner seed points,
dividing the volume of the first three dimensional space among the outer and inner seed points, thereby defining a divided volume including a plurality of divided portions, wherein each of said divided portions corresponds to one of said seed points and partially defines a boundary of said divided volume, and wherein dividing the volume includes defining each of said divided portions based upon relative positions of the corresponding seed point and at least some of the other seed points,
defining a portion of the boundary of said divided volume with a plurality of struts and one or more nodes to form a scaffold, where each strut has a first end, a second end, and a continuous elongated body between the first and second ends for each strut, and each node is an intersection of at least two struts, and
selecting at least one thickness and at least one shape for one or more struts; and
fabricating the porous structure according to the model by exposing fusible material to an energy source.

US Pat. No. 10,166,310

COMBINATION DECONTAMINATION SYSTEM FOR TRANSPORTATION ASSETS

AEROCLAVE, LLC, Winter P...

1. A decontamination system, comprising:a plurality of interconnected and insulated panels configured to form a wall and a roof and to define an interior of an enclosure configured to enclose a transportation asset;
a humidifying module in fluid communication with the interior of the enclosure and configured to raise a temperature and a humidity of the interior of the enclosure to a predetermined temperature level and a predetermined humidity level for a timed duration, wherein the humidifying module is external relative to the interior of the enclosure;
at least one insulated conduit providing fluid flow communication between the humidifying module and the interior of the enclosure via at least one first opening in the enclosure;
a dehumidifying module in fluid communication with the interior of the enclosure and configured to lower the temperature and the humidity of the interior of the enclosure from the predetermined temperature level and the predetermined humidity level to ambient levels, wherein the dehumidifying module is external relative to the interior of the enclosure; and,
at least one insulated conduit providing fluid flow communication between the dehumidifying module and the interior of the enclosure via at least one second opening in the enclosure.

US Pat. No. 10,166,308

DISSINFECTOR AND METHOD OF DISINFECTION

READYDOCK, INC., West Ha...

1. A disinfecting station, comprising:a substantially opaque enclosure configured to receive at least one device therein through at least one openable side, the enclosure further including means for selectively sealing the at least one openable side;
at least one means for supporting the at least one device; and
at least one ultraviolet light source configured to produce disinfecting wavelengths of light only when the means for selectively sealing is in a closed position;
the at least one ultraviolet light source being activatable to produce disinfecting wavelengths of light, and configured to illuminate substantially each surface of the at least one device for a predetermined period of time when the at least one device is supported by the at least one means for supporting within the enclosure and the means for selectively sealing is in the closed position.

US Pat. No. 10,166,226

CGRP RECEPTOR ANTAGONISTS

Heptares Therapeutics Lim...

1. A method of preparing a compound of formula (I), or a salt thereof or an optical isomer thereof, the method comprising:reacting a compound of formula (V) wherein Ar1 is an optionally substituted 5 membered heterocyclic ring containing at least two nitrogen atoms,
with a compound of formula (III), or an optical isomer thereof, wherein R1 is H or F,
under conditions effective to provide the compound of formula (I), or a salt thereof or an optical isomer thereof, wherein R1 is H or F and Ar1 is an optionally substituted 5 membered heterocyclic ring containing at least two nitrogen atoms:

US Pat. No. 10,166,213

DERIVATIVES OF KORORMICIN USEFUL AS ANTIBIOTICS

8. A method of treating a bacterial disease comprising administering an effective amount of the compound of claim 1 to a subject in need thereof, wherein the bacterial disease is caused by a gram-negative bacteria.

US Pat. No. 10,166,211

NITRIC OXIDE RELEASING COMPOUND, PHARMACEUTICAL COMPOSITION, USE AND SYNTHESIS METHOD THEREOF

NATIONAL CHIAO TUNG UNIVE...

1. A pharmaceutical composition comprising:a nitric oxide releasing compound of formula (I),
anda carrying agent being water or an aqueous solution;
wherein the pharmaceutical composition is an injection formulation for a human or an animal.

US Pat. No. 10,166,207

ACAMPROSATE FORMULATIONS, METHODS OF USING THE SAME, AND COMBINATIONS COMPRISING THE SAME

Synchroneuron, Inc., Wal...

1. A method comprising steps of:orally administering to a human subject in a fasted state a pill comprising about 20-95% by weight acamprosate, or a pharmaceutically acceptable salt thereof and about 1-30% by weight of a carbomer homopolymer type B.

US Pat. No. 10,166,204

SPHINGOSINE KINASE TYPE 1 INHIBITORS AND USES THEREOF

Enzo Therapeutics, Inc., ...

1. A method for treating ulcerative colitis in a patient, comprising:administering to a patient in need of treatment for ulcerative colitis a compound having the formula

US Pat. No. 10,166,203

PHARMACEUTICAL COMPOSITION FOR TREATING CANCER INCLUDING 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROP-1-EN-1-YL)PHENOL AS ACTIVE INGREDIENT

1. A method for treating cancer, comprising administering to a subject in need thereof pharmaceutical composition comprising a pharmaceutically effective amount of a compound represented by the following formula 1; and a pharmaceutically acceptable carrier

US Pat. No. 10,166,201

SUBSTITUTED HYDROXYSTILBENES AND THEIR THERAPEUTIC APPLICATIONS

RESOLVEX PHARMACEUTICALS ...

1. A method of treating an immune deficient disease with a compound having a general formula I, comprising administering to a subject in need thereof a therapeutically effective amount of the compound, the general formula I is shown as following
wherein R1 is selected from H, halogen and CN; R2 is selected from H, halogen and CN; R3 is selected from H, halogen, OCH3 and CN; R4 is H; R5 is selected from H, halogen and CN; and R6 is alkyl or cycloalkyl;
wherein the immune deficient disease is selected from a group consisting of an inflammatory bowel disease, psoriasis, eczema.

US Pat. No. 10,166,199

TRANSDERMAL PATCH COMPRISING A ROPIVACAINE FORMULATION

Buzzz Pharmaceuticals Lim...

1. A transdermal patch comprising a pharmaceutical formulation, said formulation comprising:(i) ropivacaine,
(ii) a pharmaceutically-acceptable adhesive, and
(iii) two or three excipients selected from a penetration enhancer, a hydrophilic material, and a carrier oil having a ropivacaine solubility of greater than or equal to 1.5% (w/w);wherein said ropivacaine is present in its free base form and wherein said patch further comprises a backing membrane.

US Pat. No. 10,166,188

METHOD FOR VACUUM-ASSISTED PRESERVATION OF BIOLOGICS INCLUDING VACCINES

MERIAL, INC., Duluth, GA...

1. A process for vitrifying biological material comprising the steps of:(a) formulating a liquid biological preparation, wherein the liquid biological preparation comprises at least one active biologic ingredient selected from RNA and DNA viruses; and at least one stabilizer, wherein the at least one stabilizer comprises: 1) a bulking agent consisting of dextran, present in an amount of about 6% to about 10% w/v of the stabilizer: 2) one of the following combinations of sugars: glucose+raffinose; glucose+fructose; glucose+galactose; or glucose+sucrose, wherein the glucose is present in an amount of about 1% to about 5% w/v of the stabilizer and 3) optionally aspartic acid: wherein the stabilizer is capable of reducing or eliminating cryogenic damage to the biologic ingredient;
(b) adding a portion of the liquid biological preparation of step (a) to at least one vial;
(c) loading the at least one vial into a temperature-controlled container, wherein the temperature of the temperature-controlled container is between ?15° C. and 10° C.; and
(d) reducing the moisture content of the biological preparation to less than about 5% by weight by controlled changes in pressure and temperature, comprising the following steps in the following order:
1) reducing pressure from about 10-30 mbar to about 5 mbar, over about 5-15 minutes, then holding the pressure at about 5 mbar for about 40-50 minutes;
2) reducing pressure from about 5 mbar to about 3 mbar, over about 5-10 minutes, then holding the pressure at about 3 mbar for about 10-40 minutes; and
3) reducing pressure from about 3 mbar to about 1.5-2 mbar, over about 5-10 minutes, then holding the pressure at about 1.5-2 mbar for about 5-160 minutes;thereby reducing the moisture content of the biological preparation to less than about 5% by weight, and thereby vitrifying the biological material, and wherein the one or more biologic ingredients remains at least 85% viable for at least a year after vitrification, thereby the one or more biologic ingredients is stabilized.

US Pat. No. 10,166,175

COATING OF CLAY MICRO-TUBES ON SURFACES OF HAIR AND NATURAL FIBERS

Louisiana Tech Research C...

1. A method of coloring hair comprising the step of applying to the hair a coloring mixture for at least one minute, wherein the coloring mixture comprises:(a) an aqueous based carrier liquid which is at least 75% by weight water;
(b) alumino-silicate micro-tubes having an insoluable hair dye agent loaded into a lumen of the micro-tubes to at least a 4 weight percent dye loading efficiency;
(c) wherein the micro-tubes are present in the carrier liquid in a concentration of between about 5 mg/ml and about 50 mg/ml; and
(d) wherein the mixture has a pH of between about 4.0 and about 6.0.

US Pat. No. 10,166,172

DUAL CONFIGURATION BOTTLE ASSEMBLY

HANDI-CRAFT COMPANY, St....

1. A bottle assembly comprising:a container comprising an open end, a closed end, a base portion, a neck, and a rim on the neck of the container and defining the open end of the container, the container having a central axis;
a vent assembly positionable at least in part on the rim of the container to permit venting of the container during use and comprising at least one lateral vent extending other than parallel to the central axis of the container when the vent assembly is positioned on the rim of the container, the vent assembly further comprising an inner portion including a vent tube and a top wall oriented normal to the vent tube, the lateral vent extending upward from the top wall; and
a collar assembly generally defining a closure for the container and being releasably engageable with the neck of the container over the open end thereof, the collar assembly and vent assembly being configured relative to each other to permit selective configuration of the bottle assembly between:
a first configuration in which upon releasable engagement of the collar assembly with the neck of the container when the vent assembly is on the rim of the container, the collar assembly urges the vent assembly into substantially sealing engagement with the rim of the container such that at least a majority of a cross-section of the lateral vent is disposed below the rim; and
a second configuration in which upon releasable engagement of the collar assembly with the neck of the container when the vent assembly is omitted from the bottle assembly, the collar assembly substantially sealingly engages the rim of the container.

US Pat. No. 10,166,167

FINGER VIBRATOR

Mating Components, LLC, ...

1. A device for stimulation of a body part of a user, the device comprising:a vibrator mechanism;
a body enclosing the vibrator mechanism, wherein the body includes a neck; and,
a tether, wherein the tether includes a band, wherein the tether is attached to the body;
wherein the body and the tether are configured to allow fingers of the user to engage the neck while the fingers are inserted through the band for stability and control of the device when the body is applied to the body part of the user;
wherein the body further comprises a fastening mechanism;
wherein the tether further comprises an attachment mechanism; and,
wherein the attachment mechanism and the fastening mechanism are configured to allow the body to rotate relative to the tether without detaching the body from the tether.

US Pat. No. 10,166,166

APPARATUS FOR APPLYING PERIODIC PRESSURE TO THE LIMB OF A PATIENT AND METHOD OF USE

1. An apparatus for applying periodic pressure to the limb of a patient, comprising:a cuff having a bladder, said cuff shaped and dimensioned to wrap around the limb of the patient;
a pump for inflating said bladder to a maximum cuff pressure, said maximum cuff pressure being 55 mmHg;
a plurality of pressure application modes each of which control operation of said pump;
a pressure application mode selector disposed at said cuff; and,
at least one of said plurality of pressure application modes being a step pressure application mode which includes a plurality of increasing pressure steps, followed by a dwell period at said maximum cuff pressure, followed by a plurality of decreasing pressure steps.

US Pat. No. 10,166,165

SLIP RESISTANT WALKING SURFACE FOR USE WITH A MOBILITY AID

1. An attachment to a mobility aid for improving stability of a user on a slippery surface comprising:a pair of attachment brackets, each one of said pair of attachment brackets adapted to attach to an opposing side of the mobility aid; and
a retracting slip resistant surface and cleat assembly having a pair of pads, said retracting slip resistant surface and cleat assembly removably attached to each one of said pair of attachment brackets, the pair of pads positioned to contact the slippery surface;
retraction means, attaching each of the pair of pads to said retracting slip resistant surface and cleat assembly, for alternately retracting each of the pair of pads as the mobility aid is moved forward;
cleat means, coupled to each of the pair of pads, for positioning cleats into engagement with the slippery surface when the user steps on each of the pair of pads and disengagement with the slippery surface when the user steps off of each of the pair of pads,
whereby each of the pair of pads provide a slip resistant surface being positioned for a user to step on providing secure footing.

US Pat. No. 10,166,164

ADAPTIVE COMPRESSION THERAPY SYSTEMS AND METHODS

Radial Medical, Inc., Wo...

1. A device for providing compression therapy to a body part of a patient, the device comprising:a base plate;
a drive unit configured to be placed over or against the body part, the drive unit comprising;
one or more motors disposed on the base plate;
a controller configured to control operation of the one or more motors;
a power source in electrical communication with the one or more motors and the controller; and
a plurality of movable pulleys and a plurality of fixed pulleys, wherein the plurality of fixed pulleys are disposed on the base plate such that the fixed pulleys do not move relative to each other, and wherein the movable pulleys are configured to move relative to the fixed pulleys and the base plate;
one or more physical stops that limit the movement of the movable pulleys to an area over the base plate and are configured to align the movable pulleys;
one or more drive elements configured to be tensioned by the one or more motors, wherein the one or more drive elements are threaded around the plurality of movable pulleys and the plurality of fixed pulleys; and
one or more compression mechanisms configured to be wrapped at least partially around a portion of the body part, wherein the one or more compression mechanisms are attached to the movable pulleys and are configured to be tensioned by the fixed pulleys and the movable pulleys.

US Pat. No. 10,166,163

GLASS OBJECTS INCLUDING FLOATING CREMAINS IN THE FORM OF AN IMAGE AND METHOD OF MAKING THE SAME

1. A method of making a glass object, the method comprising:contacting a colored glass article with a first gob of molten glass;
contacting a pattern of cremated remains with the first gob of molten glass to transfer the pattern of cremated remains to a surface of the first gob;
contacting the transferred cremated remains and the first gob with a second gob of molten glass; and
annealing the glass to form the glass object having an exterior surface,
the pattern of cremated remains being disposed between the colored glass article and the exterior surface of the glass object and forming an image that appears to float above the colored glass article.

US Pat. No. 10,166,157

WHEELCHAIR FRAME STRUCTURE AND METHOD FOR ADJUSTING WHEELCHAIR

MIKI HOLDINGS CO., LTD., ...

1. A wheelchair frame structure comprising:a grounding frame to which a front wheel and a rear wheel are to be provided;
a body frame mounted on the grounding frame and including a mount at which a seat is to be provided;
a height adjustment mechanism via which a relative position between the grounding frame and the body frame in a height direction of a wheelchair is changed, the height adjustment mechanism comprising:
an adjustment pole extending along the height direction and mounted on one of the body frame and the grounding frame;
a pole reception mounted on another of the body frame and the grounding frame and engaged with the adjustment pole slidably in the height direction; and
a holding portion to hold not to relatively move the adjustment pole with respect to the pole reception;
a right body frame and a left body frame each comprising the adjustment pole;
an X frame coupled to the right body frame and the left body frame, the X frame comprising rotational rods connected for mutual rotation about midpoints thereof, a right seat frame and a left seat frame for the seat being mounted on upper ends of the rotational rods;
a slider which is slidably engaged with the adjustment pole in the height direction and on which lower ends of the rotational rods are rotatably mounted; and
a slider holding portion to hold not to relatively move the adjustment pole with respect to the slider,
wherein the slider is held at a predetermined position of the adjustment pole in accordance with a desired width of the wheelchair, and the right seat frame and the left seat frame are connected to the right body frame and the left body frame, respectively.

US Pat. No. 10,166,156

DIAPER CORE WITH TRIPLE LEAK GUARD

SJ CIRCLE SDN BHD, Kulim...

1. A triple leak guard diaper core for infant and adult, comprising:a center core comprising liquid absorbing material and a plurality of hollow sections disposed on the core longitudinally, allowing the core to bend upward or forming a U-channel, and a center core top surface is provided facing a liquid discharge source;
at least one layer of bottom core wrap encapsulates the center core with a bottom core gap disposed on the center core top surface; and
at least one layer of acquisition distribution layer is disposed on the top core wrap;
wherein
the bottom core wrap is provided a bottom core bottom surface disposed opposite of the bottom core gap;
a third leak guard comprising at least one layer of non-woven top sheet encapsulating the bottom core wrap, top core wrap, and acquisition distribution layer;
at least one second leak guard comprising at least one layer of non-woven with at least one elastic band embedded therein; and
at least one first leak guard comprising at least one layer of non-woven with at least one elastic band embedded therein, is disposed over a top sheet bottom surface;
wherein
the non-woven top sheet comprising at least one elastic band disposed outside of a bottom core wrap longitudinal edge and a top sheet bottom surface, the top sheet bottom surface comprising a top sheet gap disposed over the bottom core bottom surface; and
at least one PE film is disposed on the top sheet gap and top sheet bottom surface.

US Pat. No. 10,166,154

SHAPED NON-WOVEN FABRIC FOR ABSORBENT ARTICLE, ABSORBENT ARTICLE INCLUDING SAID SHAPED NON-WOVEN FABRIC, AND METHOD FOR MANUFACTURING SAID SHAPED NON-WOVEN FABRIC

UNICHARM CORPORATION, Eh...

1. A nonwoven fabric which is shaped to be used for an absorbent article, including a first surface, a second surface which is positioned on an opposite side of the first surface, and a thickness direction, and being used in a state in which the second surface faces a configuration member of the absorbent article, whereinthe nonwoven fabric includes a thermoplastic resin fiber,
the nonwoven fabric includes a plurality of recessed portions each having an aperture portion on the first surface and each being dented toward a second surface side, and a plurality of penetration holes each being provided in a region other than the recessed portions and each penetrating through from the first surface to the second surface,
each of the plurality of recessed portions includes a circumferential wall portion which extends in the thickness direction from an edge of the aperture portion toward the second surface side, and a bottom portion which is connected to an edge of the circumferential wall portion, the edge of the circumferential wall portion being positioned on an opposite side of the aperture portion,
at least a part of the plurality of recessed portions includes a hole portion which penetrates through the circumferential wall portion from the first surface to the second surface, in the circumferential wall portion
a partially ruptured portion which is formed by a part of the nonwoven fabric and a part of which being connected to the nonwoven fabric, is dented toward the second surface side, in each of the plurality of penetration holes,
the nonwoven fabric includes a plurality of fusion portions in which the thermoplastic resin fiber is fused, in the region other than the plurality of recessed portions, and
an end portion of the partially ruptured portion includes a part of the plurality of fusion portions, at least in a part of the plurality of penetration holes.

US Pat. No. 10,166,150

THERAPEUTIC COMPRESSION DEVICE AND METHOD

Norton Salas Group, Inc.,...

1. A compression device for treating edema along a predetermined length and girth of a body part having a given contour, comprising:a mutually separated plurality of curved shells for encompassing the body part, each of said plurality of shells having an internal pad and a panel that is external to and stiffer than said internal pad, the stiffer panels of the mutually separated plurality of curved shells being arranged to encompass and confine the body part, each of said plurality of shells being adjacent to at least another one of said plurality of shells, each of said plurality of shells having a plurality of distinct edges, each adjacent pair of said plurality of shells being separated by a non-overlapping gap that is adapted to leave a portion of said body part uncovered by said plurality of shells and their internal pads; and
a ligature network routed across said plurality of shells, and atop said plurality of shells, said ligature network being divided into a plurality of independently adjustable circuits, said network including:
a plurality of tensioners directly attached to the panel of at least some of said plurality of shells, said plurality of tensioners being operable to separately adjust tension in different ones of said plurality of independently adjustable circuits to produce between said plurality of shells a pressure having a gradient for driving fluid in the body part in a desired direction, each of the independently adjustable circuits having separate portions that depart from an associated one of the plurality of tensionsers on an associated one of the plurality of shells to reach a separated pair of the plurality of distinct edges on the associated one of the plurality of shells, the separate portions adapted to be routed on the associated one of the plurality of shells in different directions relative to the girth of the body part, the separated pair of the plurality of distinct edges of the associated one of the plurality of shells facing away from each other, said plurality of tensioners contributing, compression forces perpendicular to the panels of the plurality of shells in order to apply compression forces between the panels along the length and girth of said body part, said panel having a stiffness that restricts flexing that is predominantly controlled by the contour of the body part, in order to avoid disparately redistributing compression force around the girth of said body part as tension changes in said plurality of circuits, the associated one of said plurality of tensioners being operable by increasing tension in one of said plurality of independently adjustable circuits to decrease the gap between the associated one of said plurality of shells and each of the plurality of shells adjacent to the separated pair of the plurality of distinct edges.

US Pat. No. 10,166,149

HARDENING INITIATION LAMP AND USE THEREOF

STRAXFIX.TECHNOLOGY IVS, ...

1. A hardening initiation lamp for illumination of a light-hardenable bandage, where said lamp is shaped so that it can at least partially enclose said bandage, where said lamp comprises:an inner side, which is substantially arranged to face inwards towards said bandage when the latter is illuminated;
an outer side, which is substantially arranged to face away from said bandages when the latter is illuminated, and where said lamp furthermore comprises:at least one hardening light source comprising means to initiate a hardening process in said bandage; andat least one illumination light source, which emits light in the visible spectrum, arranged to illuminate said bandage at least while said hardening process is initiated in said bandage, where both said hardening light source and said illumination light source are arranged to emit light from said inner side substantially in the direction of said bandage, and where said lamp furthermore comprises one or more transparent observation areas, where a light filter is arranged, which allows light from said illumination light source to pass through said lamp from said inner side and out through said outer side;
wherein the at least one hardening light source and the at least one illumination light source are arranged in a longitudinal direction along the hardening initiation lamp; and
wherein the one or more observation areas are interspersed between the at least one hardening light source and the at least one illumination light source.

US Pat. No. 10,166,145

INTRAOCULAR DRAINAGE DEVICE

New World Medical, Inc., ...

1. An intraocular drainage device, comprising:a main body;
a flow control device within the main body operable to allow fluid flow through the main body in a fluid flow direction;
a plurality of microgrooves formed on an outer surface of the main body, the plurality of microgrooves being arranged in parallel rows and extending substantially parallel to the fluid flow direction from a front end to a back end of the main body; and
a rigid top plate disposed within an opening in the main body, wherein the rigid top plate comprises a central portion and a pair of shelf members disposed on opposing sides of the central portion, and wherein the rigid top plate includes a top surface having an additional plurality of microgrooves that are parallel to the plurality of microgrooves on the outer surface of the main body,
wherein the rigid top plate comprises a step disposed between the pair of shelf members and the top surface, and wherein the main body is a flexible main body that includes a step that conforms to the step on the rigid top plate.

US Pat. No. 10,166,143

VERSATILE LIGHT-GUIDED OPHTHALMIC TREATMENT SYSTEM

IP LIBERTY VISION CORPORA...

1. A light-guided, ophthalmic-treatment device comprising:an ophthalmic treatment wand having a body made of light transmissive material, said ophthalmic treatment wand having a distal end;
a therapeutic applicator held at the distal end of the ophthalmic treatment wand; and
a plurality of emission ports at least partially circumscribing the therapeutic applicator;
wherein said ophthalmic treatment wand is configured to propagate light through the body to the plurality of emission ports.

US Pat. No. 10,166,141

INTRAUTERINE CONTRACEPTIVE DEVICE

SEBELA VLC LIMITED, Hami...

1. A contraceptive device for focally delivering a substance in a uterus, the contraceptive device comprising:only one elongate shape memory member, comprising:
two loops forming two tissue contact surfaces at opposing ends of the shape memory member, without any attached tissue contact members, wherein the two loops overlap when the contraceptive device is placed in a collapsed configuration inside a delivery device;
two arms extending toward one another from the two tissue contact surfaces;
two bends in the shape memory member, wherein the shape memory member crosses over itself at the two bends;
a middle portion extending down from the two bends; and
a spring portion at the bottom of the contraceptive device, formed as a loop at a midpoint between the two tissue contact surfaces; and
multiple copper sleeves disposed along a minority of a length of the shape memory member at locations to locally deliver copper, when the contraceptive device is placed in the uterus, to areas near the fallopian tubes and the cervical os, the multiple copper sleeves comprising:
at least one copper sleeve on a first arm of the two arms, near a first tissue contact surface of the two tissue contact surfaces;
at least one copper sleeve on a second arm of the two arms, near a second tissue contact surface of the two tissue contact surfaces; and
at least one copper sleeve on the middle portion, immediately above the spring portion.

US Pat. No. 10,166,139

DEVICE ENABLING FLOW OF FOOD BOLUS BETWEEN TWO STOMAS

CENTRE HOSPITALIER REGION...

1. A device enabling food bolus flow between an upstream stoma and a downstream stoma, said device comprising a pump having an entry opening and an exit opening, said pump configured for sucking a food bolus through said entry opening and releasing it through said exit opening, wherein said device further comprises:a first base onto which a food bolus collector is mounted, said first base having a first surface adapted for being fixed in a watertight manner to skin of a patient's abdomen, said base further having a second surface comprising said food bolus collector and at least one passage provided within said first base and opening into said food bolus collector;
a second base onto which the food bolus collector is mounted, said second base having a first surface adapted for being fixed in a watertight manner to the patient's skin, said second base further having a second surface comprising said food bolus collector and at least one passage provided within said second base and opening into said food bolus collector;
said pump being able to be activated by a user from the outside of said patient's body and suitable for being mounted on the patient's abdomen, in such a manner that once said device is mounted onto said patient's abdomen, food bolus flow can circulate from said upstream stoma to said downstream stoma outside of said patient's body.

US Pat. No. 10,166,130

METHODS FOR PLACING A STENT IN A BRANCHED VESSEL

Taheri LaDuca LLC, Santa...

1. A method of placing a stent at a target site within vasculature comprising a main vessel and at least one side branch vessel in fluid communication with the main vessel, the stent comprising a main lumen and a at least one side branch lumen, the method comprising:creating an incision within the vasculature;
advancing a catheter through the vasculature from the incision to the target site;
deploying the stent from the catheter at the target site wherein the stent is in a reduced dimension inside the catheter and expands to an expanded dimension in the vasculature, where deploying the stent comprises selectively tensioning the main lumen and the side branch lumen independently from one another such that the main lumen and the side branch lumen are independently repositionable in the main vessel and the side branch vessel, respectively,
Where the main lumen and side branch lumen are independently repositionable in the main vessel and side branch vessel, respectively, by expanding and reducing a diameter of the main lumen and side branch lumen.

US Pat. No. 10,166,122

APPARATUS FOR CONTROLLING PROSTHETIC ARM

Korea Institute of Scienc...

1. An apparatus to control a prosthetic hand, comprising:a display interface configured to be mounted on a head and to receive a signal of a movement of an eye;
an electromyogram input configured to receive an electromyogram signal;
a blink detector configured to detect a blink as a blink signal; and
a controller configured to control movement of the prosthetic hand based on the signal of the movement of the eye, the electromyogram signal, and the blink signal,
wherein the display interface comprises a camera configured track the movement of the eye,
wherein the display interface further comprises a basic-mode, a gesture-mode, and a grip-mode,
wherein the basic-mode is configured to enable selecting any one or any combination of any two or more of the gesture-mode, the grip mode, a command to bend an elbow of the prosthetic hand, and a command to stop operations of the prosthetic hand, and
wherein the command to stop the operations of the prosthetic hand is selected, in response to the blink detector detecting a double blink.

US Pat. No. 10,166,117

INTERVERTEBRAL IMPLANT DEVICE WITH LORDOTIC EXPANSION

Amendia, Inc., Marietta,...

1. An expandable interbody fusion implant device comprises:a frame having a first lateral side and a second lateral side and a distal end and a proximal end;
two ramp assemblies, one being a distal ramp assembly and the other a proximal ramp assembly, each ramp assembly has a translating ramp with a threaded opening, a first pivoting hinged ramp and a second pivoting hinged ramp, each pivoting hinged ramp being pivotably movable about a pinned end by a pivot pin oriented parallel to the second lateral side;
a first and a second base plate disposed between the distal end and the proximal end of the frame, each base plate being hinged to a first lateral side of the frame, the first base plate overlying the second base plate, each base plate being hinged to the distal ramp assembly and the proximal ramp assembly at the pivoting end of one of said pivoting hinged ramps of each ramp assembly, each base plate being pivotably affixed to and movable relative to the pivoting hinged ramps, each base plate having pockets for holding each pivoting hinged ramp at the pinned end transverse to the second lateral side;
a threaded drive shaft pinned to the proximal end of the frame, the drive shaft having a distal drive shaft component having threads for translating the distal ramp assembly and a proximal drive shaft component having threads for translating the proximal ramp assembly, each drive shaft component being coupled to the other, the proximal drive shaft component being affixed to the frame at the proximal end of the frame; and
wherein rotation of the drive shaft drives the translating ramp of the distal ramp assembly and the translating ramp of the proximal ramp assembly simultaneously in opposite directions as each of the first pivoting hinged ramp and the second pivoting hinged ramp pivots being moved by the translating ramps wherein each translating ramp has an exterior lift surface to guide and support the pivoting hinged ramps during expansion or contraction of the base plates, and wherein each pivoting hinged ramp has a bearing support surface configured to slide on the exterior lift surface of the translating ramp as the pivoting hinged ramp is moved by the translating ramp to selectively expand or contract a distance between the two base plates laterally relative the second lateral side of the frame, simultaneous rotation of both distal and proximal drive shaft components drives the distal and proximal ramps to selectively expand or contract a distance between both first and second base plates to a selected inclination of the first and second base plates relative to the frame over a range of lordotic angles.

US Pat. No. 10,166,114

INTERVERTEBRAL IMPLANT WITH IMPROVED SHAPE OF THE FIXING PLATE

MEDACTA INTERNATIONAL SA,...

1. An intervertebral implant for the fusion between two vertebral bodies of a vertebral column comprising:a fusion cage having a posterior side extending along an arcuate path, an anterior side extending along a straight path, and first and second lateral sides each extending between the posterior and anterior sides to define a central hole, the fusion cage adapted to be interposed between two adjacent vertebral bodies of a patient;
a fixing plate, attached to the fusion cage and having a plurality of upper passageways and lower passageways for the insertion of bone screws; and
a vertical median plane of the intervertebral implant dividing the fusion cage in two substantially symmetrical halves and also dividing the fixing plate in first and second generally asymmetrical halves, the first asymmetrical half secured directly to the anterior side of the fusion cage and having a height and width matching the anterior side of the fusion cage, and the second asymmetrical half extending outwardly and angularly offset from the anterior side of the fusion cage;
said plurality of upper passageways and lower passageways being provided only on said second asymmetrical half and being inclined towards the vertical median plane in the postero-anterior direction, the plurality of upper passageways being positioned above a top surface of the fusion cage, and the plurality of lower passageways being positioned below a bottom surface of the fusion cage.

US Pat. No. 10,166,107

FEMORAL STEM AND POST SYSTEM FOR HIP PROSTHESIS

1. A process for implanting a femoral stem for a hip joint prosthesis, comprising a femoral base having a generally elongated shape with a proximal end and a distal end, a femoral neck having a generally tubular shape extending from the proximal end of the femoral base and having a concentric axis, a lateral port on a side of the femoral base generally opposite the femoral neck and in line with the concentric axis, and a lateral post having a first end removably secured within the lateral port and a second end extending a predetermined distance from the side of the femoral base, comprising the steps of:preparing an end of a femur bone for implantation of the femoral stem;
implanting the femoral base in the femur bone;
drilling a lateral hole through a lateral cortex of the femur bone adjacent to the lateral port on the femoral stem;
measuring a depth of the lateral hole;
selecting the lateral post based upon the measured depth of the lateral hole such that the lateral post protrudes from the lateral cortex by at least 2 mm; and
installing the lateral post through the lateral hole and into the lateral port such that a portion of the lateral post protrudes from the lateral cortex of the femur bone.

US Pat. No. 10,166,101

METHODS FOR REPAIRING MITRAL VALVES

Edwards Lifesciences Corp...

1. A method of performing annuloplasty of a native mitral valve having valve leaflets and a condition resulting in diminished valve leaflet coaptation, comprising:determining that a posterior aspect of a native annulus of the native mitral valve includes an abnormality comprising a depression below a datum plane;
determining a transverse dimension and an anterior-posterior dimension of the native annulus;
selecting for implantation to the native annulus a mitral valve annuloplasty ring having a ring body covered by a suture-permeable sewing cuff, the ring body defining an orifice having a major axis perpendicular to a minor axis, the major and minor axes being generally perpendicular to a flow axis, wherein the ring body is continuous, closed around the orifice and generally rigid so that it retains its shape after implantation in opposition to the stresses that will be imparted by muscles of the heart throughout each beating cycle, and wherein
a) a major axis dimension of the ring body is less than the annulus transverse dimension, and
b) the ring body is configured to compensate for the depression of the posterior aspect of the native annulus and have a ratio of a minor axis dimension of the ring body to the major axis dimension less than the ratio of the anterior-posterior dimension to the transverse dimension of the mitral valve annulus; and
implanting the ring so as to constrict the native annulus and compensate for the depression, thereby restoring healthy coaptation between the leaflets.

US Pat. No. 10,166,091

AUGMENTED REALITY DENTAL DESIGN METHOD AND SYSTEM

Trispera Dental Inc., Ca...

1. A method of designing a dental appliance for a subject individual comprising:displaying a 3D model of the subject individual on a 3D display, the 3D model comprising:
a scanned feature comprising a dental arch of the subject individual, and a portion of a face of the subject individual and an arch for relating the arch to the face; and
an augmented reality feature comprising a dental appliance for the subject individual;
detecting an involuntary input with a sensor, wherein either (i) the involuntary input comprises a neural activity input and the sensor comprises a brain-computer interface, or (ii) the involuntary input comprises a change in a facial expression and the sensor comprises an optical sensor;
modifying the dental appliance in response to the involuntary input to provide a modified dental appliance;
repositioning the scanned feature in response to the modified dental appliance to provide a repositioned scanned feature;
updating the 3D model in response to the modified dental appliance and the repositioned scanned feature to provide an updated 3D model; and
displaying the updated 3D model on the 3D display.

US Pat. No. 10,166,083

METHOD AND SYSTEM FOR TRACKING OBJECTS IN COMPUTER-ASSISTED SURGERY

ORTHOSOFT INC., Montreal...

1. A method for tracking at least one instrument relative to a bone in computer-assisted surgery comprising:tracking, using one or more processors of a computer-assisted surgery system, a reference orientation of the bone in three axes with a reference device connected to the bone;
creating a magnetic field plane by rotating a magnet connected to one of the instrument and the bone;
using a magnetometer being mounted to the other of the instrument and the bone, producing signals as a function of at least an orientation of the magnetometer relative to the magnetic field plane; and
tracking and outputting, using one or more processors of a computer-assisted surgery system, an orientation of the instrument relative to the three axes of the reference orientation of the bone using said signals from the magnetometer subjected to the magnetic field plane, as the instrument is moved relative to the bone.

US Pat. No. 10,166,082

SYSTEM AND METHOD FOR CONTROLLING A ROBOTIC WRIST

VERB SURGICAL INC., Moun...

1. A method for controlling a robotic surgical tool during robotic surgery, comprising:receiving an input for a desired state for a distal end effector of a robotic surgical tool, the distal end effector having a robotic wrist and two distal end effector members coupled to the robotic wrist pivoting relative to each other, each distal end effector member being robotically manipulated via a pair of antagonistic cables imparting forces when tensioned;
calculating, by one or more processors, displacements of each pair of antagonistic cables based on the desired state;
generating a first command for position control to drive the robotic wrist and the distal end effector members based on the calculated displacements;
determining whether the desired state includes a desired grip force between the two distal end effector members;
responsive to a determination of the desired grip force, generating a second command for grip force control to tension at least one of the pair of antagonistic cables based on the desired grip force and a current grip force between the two distal end effector members, wherein the current grip force between the two distal end effector members is estimated based on measurements of current tensioning forces on the pairs of antagonistic cables using load cells or torque sensors;
generating a composite command by adding the second command for grip force control to the first command for position control; and
driving the distal end effector to effect the desired state based on the composite command, wherein the composite command provides simultaneous grip force control and position control for various degrees of freedom of the distal end effector.

US Pat. No. 10,166,069

NEUROMODULATION CATHETERS HAVING JACKETED NEUROMODULATION ELEMENTS AND RELATED DEVICES, SYSTEMS, AND METHODS

Medtronic Ardian Luxembou...

1. A neuromodulation catheter, comprising:an elongate shaft; and
a neuromodulation element operably connected to the shaft via a distal end portion of the shaft, the neuromodulation element being movable from a low-profile delivery state to a radially expanded deployed state, the neuromodulation element including:
a hypotube segment configured to have a first shape when the neuromodulation element is in the delivery state and a second shape when the neuromodulation element is in the deployed state, the second shape being more helical than the first;
a tubular jacket disposed around at least a portion of an outer surface of the hypotube segment, an outer surface of the jacket defining reduced-diameter segments spaced apart along its longitudinal; and
band electrodes respectively seated in the reduced-diameter segments and respectively forming closed loops extending circumferentially around the jacket,
wherein a minimum inner diameter of the band electrodes is smaller than a maximum outer diameter of jacket between the reduced-diameter segments.

US Pat. No. 10,166,068

APPARATUS AND METHODS TO MODULATE BLADDER FUNCTION

Amphora Medical, Inc., M...

1. A method of treating a bladder condition, the method comprising:a) inserting into a bladder a distal portion of an elongate ablation body defining a suction lumen and a pair of needle electrode ports;
b) drawing suction through the suction lumen and a plurality of suction ports defined in a face of the distal portion that is offset from and parallel to a central longitudinal axis at a center of the elongate ablation body, wherein the plurality of suction ports are positioned along a first side of the central longitudinal axis and face toward the central longitudinal axis, and said drawing suction causes the face of the distal portion to engage a mucosa surface of targeted bladder wall tissue within a trigone of the bladder;
c) extending a pair of electrode needles in a distal direction through the pair of needle electrode ports positioned along a second side of the central longitudinal axis that is opposite from the first side of the central longitudinal axis such that the plurality of suction ports face toward the central longitudinal axis and the pair of needle electrodes while the pair of needle electrodes penetrate into the targeted bladder wall tissue and extend generally parallel to the face of the distal portion engaging the mucosa surface of the targeted bladder wall tissue;
d) denervating said targeted bladder wall tissue within the trigone of the bladder using said pair of electrode needles;
e) relocating said pair of electrode needles to a next targeted location within the trigone of the bladder;
f) denervating said next targeted location with said pair of electrode needles; and
g) repeating steps b) through f) until regions of denervated tissue and untreated tissue are created in the bladder.

US Pat. No. 10,166,062

HIGH-RESOLUTION MAPPING OF TISSUE WITH PACING

EPiX Therapeutics, Inc., ...

1. A system for delivering ablative energy to targeted cardiac tissue of a subject and for confirming successful ablation of said targeted cardiac tissue, comprising:a catheter comprising a high-resolution electrode along a distal end of the catheter;
an energy delivery module comprising a processor, the energy delivery module being configured to operatively couple to the catheter, wherein the energy delivery module is configured to energize the high-resolution electrode to deliver the ablative energy to the targeted cardiac tissue adjacent the high-resolution electrode; and
a pacemaker, wherein the pacemaker is integral to the energy delivery module;
wherein the system is configured to detect a signal relating to a localized heart rate at the high-resolution electrode via the high-resolution electrode;
wherein the energy delivery module is configured to selectively pace cardiac the targeted tissue in order to attain capture of the heart of the subject;
wherein the system is configured, via a predetermined pacing signal provided to the catheter by the pacemaker, to increase the heart rate of the subject from a baseline level to an elevated level, the predetermined pacing signal comprising a pacing level greater than a pre-ablation pacing threshold level;
wherein the processor is configured to terminate the energization of the high-resolution electrode after loss of capture of the heart of the subject; and
wherein the high-resolution electrode comprises a distal portion and a proximal portion, the distal and proximal portions of the high-resolution electrode being operatively coupled to each other using at least one filtering element and wherein the distal and proximal portions function as a single electrode when the ablative energy is delivered by the high-resolution electrode to the targeted cardiac tissue, wherein the filtering element comprises a capacitor configured to energize both the proximal and distal portions when the ablative energy is delivered by the high-resolution electrode to the targeted cardiac tissue, wherein the predetermined pacing signal is configured to be delivered via the distal and proximal portions of the high-resolution electrode.

US Pat. No. 10,166,055

METHOD AND APPARATUS FOR BONE FIXATION

Biomet C.V., Warsaw, IN ...

1. A fastener assembly for use with fracture fixation, comprising:a cannulated proximal fastener member having a proximal fastener head configured to be seated on an exterior side of a bone, an opposed distal end and an internal wall defining an internal keyed anti-rotation feature and having an exterior wall defining a diameter, wherein a diameter of the head is larger than the diameter of the exterior wall such that the head has a lower surface configured to be seated against an exterior bone surface or a bone plate;
a distinct distal fastener member having a proximal end defining an internal bore and an external keyed anti-rotation feature, and a distal end defining a bone anchor; and
a distinct internal fastener member configured to be positioned in the proximal fastener member and threadably coupled to the distal fastener member such that the proximal end of the distal fastener member is telescopically received in the distal end of the proximal fastener member;
wherein rotation of the internal fastener member in a first rotational direction telescopically retracts the distal fastener member into the proximal fastener member so as to be adapted to compress a bone fracture, and rotation of the internal fastener member in a second opposite rotational direction extends the distal fastener member relative to the proximal fastener member,
and further comprising a retention arrangement including one or more pins mounted to the proximal fastener member that engage a groove around a head of the internal fastener member and are configured to prevent axial movement of the internal fastener member relative to the proximal fastener member while allowing relative rotational movement of the internal fastener member.

US Pat. No. 10,166,050

INSTRUMENT FOR CONNECTING A CORRECTION ROD TO A BONE SCREW

SILONY MEDICAL INTERNATIO...

1. Instrument for connecting a correction rod to a bone screw, said instrument having an axial longitudinal direction and comprising an external first housing part, which comprises a cylindrical hollow portion having an internal thread and a portion that is approximately the shape of a half-shell and that forms a first clamp leg, said instrument comprising an external second housing part, which is approximately the shape of a half-shell and forms a second clamp leg that is hinged on the first clamp leg so as to be pivotable in a limited manner about a pivot axis that extends orthogonally to the axial longitudinal direction, and said instrument comprising an adjustment part, which axially penetrates the external housing parts and is thus internal, and which comprises an external thread on one portion and can thus be screwed into the internal thread of the external first housing part, a proximal end of the adjustment part being manually graspable from outside the housing parts for this purpose, and said instrument comprising a rod pressure part, which can be axially placed against the correction rod and which is axially coupled to the adjustment part but can rotate about the axial longitudinal direction relative to the adjustment part, such that rotational movements of the adjustment part are not transmitted to the rod pressure part, and the clamp legs surrounding the rod pressure part in a shell-like manner and guiding same in a longitudinally slidable manner, said clamp legs each comprising a distal end and a proximal end, the relevant distal end engaging on the bone screw and the proximal end being actuatable by finger pressure of the operating surgeon, characterized in that the distal ends of the two clamp legs are designed such that they comprise an accommodation opening having a radial transverse direction for accommodating the correction rod in said radial transverse direction, and in that said radial transverse direction extends orthogonally to the pivot axis of the clamp legs, further characterized in that, in a pivot joint for the two clamp legs, at least one joint pin projects radially inwards and the inner end thereof engages in a guide groove that extends in the axial longitudinal direction on a radial outer face of the rod pressure part and thus secures same against rotation but guides same in a longitudinally slidable manner in the longitudinal direction.

US Pat. No. 10,166,046

IMPLANT FOR IMMOBILIZING CERVICAL VERTEBRAE

Life Spine, Inc., Huntle...

1. An implant for immobilizing a first vertebra relative to a second vertebra, the implant comprising:a first component having a hook for attachment to a posterior arch of the first vertebra, a right wing, a left wing, a right element holder situated on the right wing, and a left element holder situated on the left wing, the right element holder free to translate laterally along the right wing and translate rotationally with respect to the right wing, the left element holder free to translate laterally along the left wing and translate rotationally with respect to the left wing;
a second component having a body configured to abut the second vertebra, a first rod holder extending from the body, and a first post extending from the body and configured to be received in the right element holder of the first component;
a third component having a body configured to abut the second vertebra of the spine, a second rod holder extending from the body, and a second post extending from the body and configured to be received in the left element holder of the first component; and
a rod configured to be received in and extend between the first rod holder of the second component and the second rod holder of the third component.

US Pat. No. 10,166,040

ORGAN RESECTION TOOL

National University Corpo...

1. An organ resection tool, comprising:a first brush-like structure connected to a central conductor;
a second brush-like structure directly physically connected to an external conductor and not connected to the central conductor;
wherein the first brush-like structure is capable of radiating microwaves generated by a microwave oscillator and the second brush-like structure is capable of receiving the microwaves simultaneously, wherein the microwaves radiate within a microwave irradiation range;
wherein the microwaves generated by the microwave oscillator are transmittable to the first brush-like structure via the central conductor, the first brush-like structure is capable of radiating the microwaves within the microwave irradiation range, the second brush-like structure is capable of receiving the microwaves if the microwaves are within the microwave irradiation range and transferring the microwaves to the external conductor;
wherein the second brush-like structure comprises a plurality of brush units which each radiate outward to a tip portion of the organ resection tool;
wherein at least one from the group consisting of the first brush-like structure and the second brush-like structure has a stiffness and elasticity capable of scraping an organ and applying a pressure to living tissue when brought into contact with the living tissue.

US Pat. No. 10,166,022

METHOD AND APPARATUS FOR BONE FIXATION

Biomet C.V., Warsaw, IN ...

1. An orthopedic implant for use in fixation or fusion of bone segments, the implant comprising:a longitudinally extending bridge member having an upper surface portion, an opposed lower surface portion and opposed sides extending between the upper and lower surface portions, at least the opposed sides being formed of a porous metal construct having a porous metal outer surface, wherein the opposed sides of the bridge member taper outwardly all the way from the lower surface portion up to the upper surface portion such that the bridge member includes a wedge shaped structure with the lower surface portion having a smaller width than a corresponding width of the upper surface portion; and
first and second cylindrical fixation members integrally connected with the bridge member at opposed longitudinal ends of the bridge member, the first and second fixation members including a cylindrical body having a body width in a direction perpendicular to a longitudinal axis of the bridge member greater than a corresponding bridge width of the bridge member and a member length between a top surface portion and an opposed bottom surface portion greater than a corresponding bridge length of the bridge member from the upper surface portion to the lower surface portion, at least the body being formed of the porous metal construct and having the porous metal outer surface;
wherein the bridge member and the first and second cylindrical fixation members include a solid core structure including a bridge core and integrally connected first and second cylindrical fixation member cores and the solid core structure is at least partially covered by the porous metal outer surface and wherein the lower surface portion of the bridge member is an exposed surface of the bridge core and is not covered by the porous metal;
wherein the implant is adapted to be positioned into the bone segments such that the bridge member is adapted to fix the bone segments in a first direction perpendicular to the longitudinal axis and the fixation members are adapted to fix the bone segments in a second direction parallel to the longitudinal axis.

US Pat. No. 10,166,014

HEART VALVE PROSTHESIS AND METHOD

Percutaneous Cardiovascul...

1. An atrioventricular heart valve prosthesis for replacing an atrioventricular valve of a heart, said prosthesis comprising a housing component and a valve component;wherein said housing component comprises:
a housing body having an atrial end having a diameter, a ventricular end having a diameter, and a housing passage extending from the atrial end to the ventricular end;
said housing body being configured to be located in, or adjacent to and communicating with, a native atrioventricular valve orifice of the heart;
a ventricular anchoring mechanism secured to said housing body and configured to engage chordae tendineae of the heart downstream of the native atrioventricular valve orifice and within the ventricle of the heart communicating with the native atrioventricular valve orifice, said ventricular anchoring mechanism comprising a super elastic, shape memory, nickel-titanium alloy;
said housing component being configurable between a housing collapsed state for delivery to the native atrioventricular valve orifice via catheterization and a housing expanded state to engage said ventricular anchoring mechanism with the chordae tendineae of the heart to fix said housing body in relation to the native atrioventricular valve orifice;
an atrial anchoring mechanism secured to said housing body and configured to extend over tissue surrounding the native atrioventricular valve orifice within the atrium of the heart communicating with the native atrioventricular valve orifice and to prevent said housing component from migrating into the ventricle when said housing component is in the housing expanded state, said atrial anchoring mechanism comprising a shape memory, nickel-titanium alloy; and
an annular sealing member extending radially outwardly from said housing body at a location between the atrial end and the ventricular end of said housing body and configured to inhibit blood flow from the ventricle to the atrium when said housing component is in the housing expanded state with said housing body disposed within the native atrioventricular valve orifice, the sealing member having an outer diameter greater than the diameters of the atrial end and the ventricular end of said housing body;
further wherein said valve component comprises:
a valve body having a valve passage extending therethrough;
said valve body being separate from said housing component and being configured to be located at least partially within said housing passage with said valve passage extending along said housing passage; and
one or more flexible valve elements secured to said valve body and extending across said valve passage for blocking blood flow in a first direction through said valve passage whilst allowing blood flow in an opposing second direction through said valve passage;
said valve component being configurable between a valve collapsed state for delivery to said housing passage via catheterization following delivery of said housing component to the native atrioventricular valve orifice and with said housing body in said housing expanded state, and a valve expanded state to engage said housing component and/or structure of the heart to fix said valve body at least partially within said housing passage.

US Pat. No. 10,166,013

FLEXIBLE MEMBER FOR ANGLED SYSTEM

Medtronic Xomed, Inc., J...

4. An instrument assembly, comprising:a flexible tube, including,
a first rigid member having a first lumen and a first end;
a second rigid member having a second lumen and a second end; and
a flexible portion having a third end coupled to the first end of the first rigid member and a fourth end coupled to the second end of the second rigid member;
wherein the flexible portion has a third lumen;
wherein the first lumen, the second lumen, and the third lumen are configured to be coupled to form a first liquid flow path;
wherein the flexible portion is configured to transfer a working torque from the first rigid member to the second rigid member;
wherein the flexible portion includes:
an inner polymer tube extending a first distance from the third end coupled to the first end of the first rigid member to the fourth end coupled to the second end of the second rigid member; and
an external coat formed of a plurality of wires twisted around the inner polymer tube extending a second distance from a fourth end to a fifth end;
wherein the second distance is greater than the first distance;
wherein the fourth end is coupled to the first rigid member beyond the inner polymer tube and the fifth end is coupled to the second rigid member beyond the inner polymer tube.

US Pat. No. 10,166,002

ULTRASONIC BONE MOTION TRACKING SYSTEM

OMNIlife science, Inc., ...

1. A computerized bone motion tracking system for non-invasively tracking a bone of a subject in three-dimensional space comprising:a 3D or 4D volumetric ultrasound imaging transducer comprising a 2D array of transducer elements configured to capture 3D image pixel volumes in real-time, wherein the 3D or 4D volumetric ultrasound imaging transducer is further configured to
(a) capture a first reference image volume I0 of a bone surface at an initial time t0,
and
(b) capture a second image volume I1 of the bone surface at a second time t1,
a three-dimensional position measuring device configured to measure a three-dimensional position of the 3D or 4D volumetric ultrasound imaging transducer at the times t0 and t1 and associating each position with the corresponding image volumes I0 and I1; and
a computer configured to
determine an initial position of the bone using the first reference image volume I0,
search for a relative position of image volumes I0 and I1 for which overlapping portions of the image volumes of I0 and I1 are closest aligned to one another and define this position as a best-match position, wherein the search is limited to a region of interest that includes pixels representing the bone surface in at least one of the first reference image volume and the second image volume, wherein the region of interest is a subset of each of the image volumes I0 and I1 and is selected by real-time segmentation,
determine a 3D transformation between the first reference image volume and the second image volume that corresponds to the best-match position, and
display the imaged bone surface on a display and show movements thereof in real-time.

US Pat. No. 10,165,984

CONFIGURABLE VITAL SIGNS SYSTEM

WELCH ALLYN, INC., Skane...

1. A system, comprising:an inflatable cuff configured to be disposed around a limb of a patient, and to transition a vessel within the limb from unoccluded to at least partially occluded upon inflation; and
a controller configured to determine an estimate of a hemodynamic parameter of the patient based at least in part on one or more measurements performed while transitioning the vessel, with the cuff, from unoccluded to at least partially occluded, wherein
performing the one or more measurements includes determining an initial value comprising one of a cuff pressure, cuff volume, blood pressure, heart rate, SpO2, or temperature value, and wherein determining the estimate of the hemodynamic parameter includes:
determining, with the controller, a difference between the initial value and a baseline associated with the initial value,
replacing the baseline with the initial value, in a memory associated with the controller, if the difference is outside of a predetermined range,
determining the estimate of the hemodynamic parameter based on values determined during the one or more measurements, and
outputting the estimate of the hemodynamic parameter.

US Pat. No. 10,165,970

TISSUE OXIMETER INTRAOPERATIVE SENSOR

ViOptix, Inc., Newark, C...

1. A method comprising:forming an oximeter probe comprising a sensor head and a handle;
on the probe face of the sensor head, forming first, second, and third sensor structures;
positioning the second sensor structure at a first distance from the first sensor structure;
positioning the third sensor structure at a second distance from the first sensor structure, wherein the first distance is different from the second distance;
coupling a light emitting diode to the first sensor structure;
coupling a first photodiode the second sensor structure;
coupling a second photodiode the third sensor structure;
coupling a processing circuit to the light emitting diode, first photodetector, and second photodetector;
coupling a battery to the light emitting diode, first photodetector, second photodetector, and processing circuit; and
coupling a flexible member, comprising a spring constant, coupled between the sensor head and the handle, whereby the flexible member adjusts a pressure that is applied to a tissue being measured by the sensor head to be less than a pressure applied by a user at the handle.

US Pat. No. 10,165,964

SYSTEMS AND METHODS FOR QUANTIFYING REGIONAL FISSURE FEATURES

Vida Diagnostics, Inc., ...

1. A method for analyzing a patient based on a volumetric pulmonary scan comprising:receiving a first volumetric pulmonary scan representative of the patient's pulmonary structure;
mapping the first volumetric pulmonary scan to a reference domain;
determining one or more fissure features associated with a plurality of regions in the reference domain and within the first volumetric pulmonary scan;
comparing, in each of the plurality of regions, the determined one or more fissure features to a plurality of fissure atlases, each atlas comprising statistical data associated with the one or more fissure features for a population based on regional analysis of volumetric pulmonary scans of that population;
classifying the patient into one or more of the populations based on the comparison of the determined one or more fissure features.

US Pat. No. 10,165,958

METHOD FOR DETECTING POSITION OF SIGNAL SOURCE IN LIVING BODY, AND DEVICE FOR DETECTING POSITION OF SIGNAL SOURCE IN LIVING BODY

TORAY ENGINEERING CO., LT...

7. A device for detecting a position of a signal source in a living body, based on voltages generated at a set of electrodes arranged on a surface of the living body, the device comprising:at least three electrodes forming the set of electrodes and being arrangeable on the surface of the living body;
a connector alternately connecting a first external resistance and a second external resistance in parallel between the set of electrodes and a ground potential;
a measurer measuring, in a state where the set of electrodes has been arranged on the surface of the living body, first voltages Vi (i=1, 2, 3) which are generated at the respective electrodes when the connector connects the first external resistance in parallel between the set of electrodes and the ground potential, and second voltages V?i (i=1, 2, 3) which are generated at the respective electrodes when the connector connects the second external resistance in parallel between the set of electrodes and the ground potential; and
a detector calculating three ratios Vi/V?i (i=1, 2, 3) from the first voltages Vi and the second voltages and detecting the position of the signal source in the living body based on the three ratios Vi/V?i (i=1, 2, 3).

US Pat. No. 10,165,950

VITAL SIGNS MONITOR

WELCH ALLYN, INC., Skane...

1. A multi-parametric vital signs monitoring system, said system comprising:a vital signs monitoring device, said monitoring device including a portable power supply enabling said monitoring device to operate in a first stand-alone mode and a wireless transceiver enabling said monitoring device to operate in an alternative second wireless networked mode with at least one remote station; and
a charging cradle adapted to receive said vital signs monitoring device, said charging cradle permitting said compact vital signs monitoring device to operate in a powered mode when said monitoring device is received by said charging cradle, said monitoring device being operable in said second networked mode when said monitoring device is in said charging cradle;
said vital signs monitoring device being defined by a compact housing, the compact housing including:
a pair of half housing sections, wherein one of the pair of half housing sections retains a display screen of the vital signs monitoring device and the other of the pair of half housing sections includes at least one connection port of the vital signs monitoring device for connection to said charging cradle,
a rubberized bladder disposed peripherally between the half housing sections and continuously extending about the entire periphery of the housing in order to assist the monitoring device from impact or shock loads and to prevent ingress of dust or contaminants into an interior of the housing, and
a pair of tabs in which each of the tabs is disposed on opposing lateral sides of one of the half housing sections, the tabs enabling attachment to a patient-wearable harness that receives the vital signs monitoring device, the housing of the vital signs monitoring device including a bottom facing surface, a rear facing surface and two opposing lateral sides in which a latching member and the connector port enabling connection to the charging cradle is formed in the bottom facing surface and a plurality of mounting feet extend from the rear facing surface of the housing to enable placement of the monitoring device on a flat surface,
the charging cradle being defined by an open-topped receptacle sized to retain a lower portion of the vital signs monitoring device and comprising a hanging bracket configured for connecting to a bed rail, the open-topped receptacle including a bottom surface having an electrical connector for engaging the connector port of the monitoring device and a latch for engaging the latching member of the monitoring device, the charging cradle further including a release button for disengaging the latch from the latching member.

US Pat. No. 10,165,949

ESTIMATING POSTURE USING HEAD-MOUNTED CAMERAS

Facense Ltd., Kiryat Tiv...

1. A system comprising:a frame configured to be worn on a user's head;
first and second cameras, physically coupled to the frame at locations that are to the right and to the left of a symmetry axis that divides the user's face to its right and left sides, respectively, and less than 15 cm away from the user's head;
wherein the first and second cameras are oriented downward such that portions of the user's torso are in respective fields of view of the first and second cameras when the user stands upright; and
a computer configured to estimate an angle between the user's head and the user's torso based on data received from the first and second cameras and orientation of the frame.

US Pat. No. 10,165,941

OPTICAL COHERENCE TOMOGRAPHY-BASED OPHTHALMIC TESTING METHODS, DEVICES AND SYSTEMS

Doheny Eye Institute, Lo...

1. An optical coherence tomography instrument comprising:an eyepiece for receiving at least one eye of a user;
at least one target display visible through said eyepiece;
a light source that outputs light that is directed through the eyepiece to the user's eye;
an interferometer configured to produce optical interference using light reflected from the user's eye;
an optical detector disposed so as to detect said optical interference; and
electronics coupled to the target display and said detector and configured to provide an output based on optical coherence tomography measurements obtained using said interferometer,
wherein said electronics are further configured to produce features on said target display of varying size and receive user responses to test the user's visual acuity, and
wherein the optical coherence tomography instrument is configured to allow the user to self-administer the visual acuity test.

US Pat. No. 10,165,889

FOOD STEAMER AND RACK SYSTEM

Meyer Intellectual Proper...

1. A cookware apparatus, the apparatus comprising:a) a vessel to retain a fluid, the vessel having a bottom and substantially upright sidewalls extending between the bottom and an upper rim of the vessel;
b) a spacer adapted to be selectively disposed on the vessel, the spacer comprising one or more generally upright sidewalls forming a perimeter of the spacer and defining an interior hollow therebetween, the spacer having an open bottom, wherein, when the spacer is disposed on the vessel, a lower rim of the spacer and the upper rim of the vessel are in generally sealed engagement;
c) a perforated rack adapted to be selectively positioned within the hollow between the lower rim and an upper rim of the spacer, wherein the perforated rack stably engages a portion of the sidewall when positioned within the hollow; and
d) a support rack defining an outer perimeter positionable within the hollow of the spacer, wherein the support rack is adapted to support the perforated rack when the spacer within which the perforated rack is positioned is lowered to surround at least an upper portion of the support rack.

US Pat. No. 10,165,866

BENCH

Furniture of America, Inc...

1. A furniture assembly, comprising:a bed frame having a headboard; and
a bench which comprises:
a base frame which comprises a seat frame and a leg frame downwardly extended from said seat frame; and
a back frame upwardly extended from said seat frame, wherein a shape of said back frame matches with a shape of said headboard of said bed frame, wherein said back frame comprises a back supporting panel upwardly extended from said seat frame, a back cushion overlapped on said back supporting panel, and a back enclosing layer that wraps said back cushion at said back supporting panel, wherein said seat frame comprises a seat supporting panel, a seat cushion overlapped on said seat supporting panel, and a top enclosing layer that wraps said seat cushion on said seat supporting panel, wherein a bottom edge of said back supporting panel of said back frame is upwardly and perpendicularly coupled with a rear edge of said seat supporting panel of said seat frame, wherein said back frame further comprises a coupling panel extended from said bottom edge of said back supporting panel to couple at a bottom of said seat frame.

US Pat. No. 10,165,828

ARTICLE OF FOOTWEAR WITH DECOUPLED UPPER

NIKE, Inc., Beaverton, O...

1. An article of footwear, comprising:a longitudinal direction extending along a major axis of the article of footwear and a lateral direction extending along a minor axis of the article of footwear;
an upper and a sole structure;
a first side extending along the longitudinal direction of the article of footwear;
a second side extending along the longitudinal direction of the article of footwear; the first side being on an opposite side of the article of footwear from the second side;
a connecting member including a sheet of material, the sheet of material forming the connecting member being folded along the longitudinal direction in a linear orientation along an entire length of the connecting member such that the connecting member includes an upper layer and a lower layer;
the upper layer being attached to the upper along the first side and the lower layer being attached to the sole structure along the first side; the second side of the sole structure and the second side of the upper being directly coupled to each other;
the upper layer and the lower layer of the connecting member being decoupled from one another at the first side such that the upper layer is configured to move substantially independently of the lower layer at the first side, wherein the decoupled upper layer and the decoupled lower layer allow a lower periphery of the upper to move substantially independently of an upper periphery of the sole structure on the first side of the article of footwear; and
wherein the first side is a medial side.

US Pat. No. 10,165,816

ADORNING APPARATUS AND HEADWEAR USING THE SAME

YUPOONG, INC., Seoul (KR...

1. A headwear and adorning apparatus assembly, comprising:a size controller having a male size control portion having a base end affixed to the headwear and a female size control portion having a base end affixed to the headwear, the male size control portion having a distal end, the female size control portion having a distal end, the distal ends affixing to one another, the distal ends defining an overlapping portion for selectively adjusting a head size of the headwear;
an adorning apparatus having an adorning portion and a support portion to support the adorning portion, the adorning apparatus being attachable to and detachable from the size controller,
wherein:
the size controller spans across an opening portion defined by the headwear,
the male size control portion has a coupling protrusion and the female size portion has a coupling hole,
the adorning portion has a front surface and a back surface, the front surface being three-dimensionally adorned and the back surface being flat,
the support portion extends away in a vertical direction from the adorning portion for a distance that is equal to a width of the size controller, the support portion being interposed between the male size control portion and the female size control portion and disposed within the overlapping portion,
the support portion is rectangular and is thinner than the adorning portion,
the support portion has a detachable coupling portion for detachably being coupled to the male size control portion,
a recess portion is formed in the size controller, and extended in a head circumferential direction corresponding to a thickness and a width of the support portion to receive the support portion,
the recess portion is located within a space defined by the opening portion, and
a height of the coupling protrusion is greater than a sum of a thickness of the size controller and the thickness of the support portion.

US Pat. No. 10,165,810

CUT RESISTANT GLOVE, AND MANUFACTURING METHOD OF CUT RESISTANT GLOVE

Showa Glove Co., Hyogo (...

1. A cut resistant glove comprising a glove main body manufactured by plating knitting using a ground yarn and an additional yarn, wherein the ground yarn comprises a core material, and a cover yarn wound around the core material, wherein the core material comprising a string made of a metal or glass fiber, wherein the core material further comprising a support yarn made of an organic fiber arranged along the string, wherein an average thickness of the support yarn being no less than 45 dtex and no greater than 100 dtex, and the additional yarn being made of organic fiber and comprising a core yarn and a cover yarn wound around the core yarn of the additional yarn, an elongation rate of 30-g load to 3-g load of the additional yarn is no greater than 30%, an average thickness of the ground yarn is no less than 135 dtex and no greater than 440 dtex, and an average thickness of the additional yarn is no less than 135 dtex and no greater than 670 dtex, and wherein a ratio of the average thickness of the additional yarn to the average thickness of the ground yarn is no less than 0.9 and no greater than 2.5, and the cut resistant glove is composed of stitches of at least 13 gauges and is provided with a coating layer made of a resin or rubber on an outer surface side of the glove.

US Pat. No. 10,165,797

CIGARETTE DISTILLATION AND ATOMIZATION DEVICE

SMISS TECHNOLOGY CO., LTD...

1. A cigarette distillation and atomization device, comprising: a support, an air inlet, and an air outlet, wherein the air inlet and the air outlet are provided on the support; a first heating system and a second heating system are provided in the support; the first heating system and the second heating system are hermetically connected; the first heating system comprises a first cylinder; the second heating system comprises a second cylinder; an inner cavity of the second cylinder is used to place a cigarette; a height of the second cylinder is 20 mm-64 mm, and an inner diameter of the second cylinder is equivalent to an outer diameter of the cigarette; the first heating system is provided with a first heating circuit used to preheat cold air that enters the first heating system, the second heating system is provided with a second heating circuit used to dilute, bake, and atomize the cigarette when the cigarette placed in the second heating system; air entering the air inlet is heated by the first heating system to form a hot air flow, and the hot air flow enters the second heating system; and the hot air flow and the second heating system simultaneously heat the cigarette placed in the second cylinder to form smoke, and the smoke goes out from the air outlet.

US Pat. No. 10,165,786

PASTRY BAG, AUXILIARY MEMBER, DECORATION FORMING TOY AND DECORATION FORMING TOY SET

EPOCH COMPANY, LTD., Tok...

1. A pastry bag comprising:a container configured to contain a creamy substance;
a connecting section at least partially disposed inside the container and extending outside of the container;
a nozzle connected to the container by the connecting section, the nozzle including an opening through which the creamy substance passes out of the container; and
an auxiliary member at least partially disposed inside of one or both of the connecting section and the nozzle, the auxiliary member comprising:
a fixing portion that holds the auxiliary member to the nozzle;
a positioning portion to be brought into contact with a creation surface on which a decoration is to be created, the positioning portion extending through the opening of the nozzle;
at least one connecting rod connecting the positioning portion and the fixing portion;
at least one front rib formed between a part of the positioning portion on a front side of the connecting rod and a front surface of the connecting rod, the at least one front rib extending from the at least one connecting rod towards the opening of the nozzle; and
at least one rear rib connecting a part of the positioning portion on a rear side of the connecting rod and a rear surface of the connecting rod, the at least one rear rib extending from the at least one connecting rod away from the opening of the nozzle,
wherein the fixing portion is sandwiched between the nozzle and the connecting section.

US Pat. No. 10,165,756

WIRELESS LOCATION ASSISTED ZONE GUIDANCE SYSTEM INCORPORATING A RAPID COLLAR MOUNT AND NON-NECROTIC STIMULATION

GPSIP, Inc., Oshkosh, WI...

1. A collar-mounted GPS and stimulation unit incorporating a rapid collar mount and non-necrotic stimulation, comprising:a body having a first major surface, a second major surface spaced from said first major surface, a superior lateral edge adjoining said first and second major surfaces, an inferior lateral edge distal and inferior to said superior lateral edge, a first longitudinal end, and a second longitudinal end distal to said first longitudinal end;
a plurality of stimulation electrodes within an exposed electrode plane substantially parallel with and immediately adjacent to said body second major surface;
a GPS sensor and associated electronics contained within said body, wherein said associated electronics further comprises a capacitive detector coupled to said plurality of stimulation electrodes, said capacitive detector configured to detect a capacitance of fur adjacent to said plurality of stimulation electrodes when said body is properly secured to a dog and configured to turn on said GPS sensor responsive to said fur capacitance detection;
a first quick-mount retention clip extending from said superior lateral edge adjacent to said first longitudinal end to a first clip termination and defining a first gap between said first clip termination and said first longitudinal end, said first gap configured to receive and retain a first collar portion between said first quick-mount retention clip and said first longitudinal end;
a second quick-mount retention clip extending from said inferior lateral edge adjacent to said first longitudinal end to a second clip termination and defining a second gap between said second clip termination and said first longitudinal end, said second gap configured to receive and retain a second collar portion between said second quick-mount retention clip and said first longitudinal end;
said first and second clip terminations spaced from each other by a distance less than a distance between said first and second quick mount retention clips adjacent to said first longitudinal end and thereby configured to operatively entrap a collar therebetween;
a third quick-mount retention clip extending from said superior lateral edge adjacent to said second longitudinal end to a third clip termination and defining a third gap between said third clip termination and said second longitudinal end, said third gap configured to receive and retain a third collar portion between said third quick-mount retention clip and said second longitudinal end; and
a fourth quick-mount retention clip extending from said inferior lateral edge adjacent to said second longitudinal end to a fourth clip termination and defining a fourth gap between said fourth clip termination and said second longitudinal end, said fourth gap configured to receive and retain a fourth collar portion between said fourth quick-mount retention clip and said second longitudinal end;
said third and fourth clip terminations spaced from each other by a distance less than a distance between said third and fourth quick mount retention clips adjacent to said second longitudinal end and thereby configured to operatively entrap said collar therebetween.

US Pat. No. 10,165,755

WIRELESS LOCATION ASSISTED ZONE GUIDANCE SYSTEM REGION LOOKUP

GPSIP, Inc., Oshkosh, WI...

1. A wireless location assisted zone guidance system comprising:a housing;
an electrical power source contained within said housing;
at least one animal stimulation apparatus coupled with said housing and electrically powered by said electrical power source;
a wireless location determination apparatus contained within said housing, powered by said electrical power source, and adapted to operatively generate electrical latitude and longitude information representative of a current position of said housing;
an electrical processor coupled to said wireless location determination apparatus and configured to receive said electrical latitude and longitude information therefrom;
memory electrically accessible by said electrical processor;
an electrically powered human interface adapted to convert electrical signal input to human-comprehendible output and adapted to receive electrical signals representative of human input;
a data table stored in said electrically accessible memory uniquely locating at least two geographically separated assisted guidance regions;
said electrical processor configured to operatively compare said received electrical latitude and longitude information to said data table to generate a first represented current position within said data table and to generate a second represented current position that is subsequent to said first represented current position and further configured to vary an output of said at least one animal stimulation apparatus responsive to said second represented current position relative to said first one of said at least two assisted guidance regions when said first represented current position of said housing is within said first one of said at least two assisted guidance regions, and configured to generate and convey a query to said human interface when said first represented position is outside of each one of said at least two assisted guidance regions.

US Pat. No. 10,165,728

EDGER WITH SHIELDING ASSEMBLY

Echo Incorporated, Lake ...

1. An edger comprising:a main frame that can be advanced controllably relative to subjacent terrain;
a cutting assembly on the main frame;
a drive for rotating the cutting assembly around a first axis,
the cutting assembly configured to produce a trench in underlying terrain as the cutting assembly is rotated by the drive in operation,
the produced trench having a width extending along the first axis,
the cutting assembly having a perimeter edge with a contour extending over an axial distance; and
a shielding assembly defining a radially inwardly facing surface that resides radially outside of the perimeter edge of the cutting assembly,
the radially inwardly facing surface having a shape that is at least nominally matched to the contour of an axial extent of the perimeter edge of the cutting assembly so that as the cutting assembly rotates the radially inwardly facing surface and perimeter edge of the cutting assembly cooperate to each avoid buildup of foreign matter on the other,
the radially inwardly facing surface, with the edger viewed in cross-section along a plane containing the first axis, having a non-straight shape where the radially facing surface extends over an axial extent of the perimeter edge of the cutting assembly.
US Pat. No. 10,167,382

SEALING MATERIAL

ENRICHMENT TECHNOLOGY COM...

1. A sealing material for the production of a gas seal, wherein the constituents of the sealing material include a bromobutyl elastomer in an amount of 100 parts by weight, a filler material in an amount between 10 and 100 parts by weight for setting the volume of the sealing material, a curing agent of a peroxide in an amount between 0.5 and 3.0 parts by weight for curing the sealing material, a material for acid neutralization, and a cross-linking component serving as a multi-functional reagent for peroxidically cross-linked elastomers in an amount between 0.1 and 2.0 parts by weight for further enhancing gas-tightness of the peroxidically cross-linked sealing material, wherein the material for acid neutralization consists essentially of an organic binder and activated magnesium oxide (MgO) embedded in the organic binder.
US Pat. No. 10,167,449

HUMAN BROWN ADIPOSE DERIVED STEM CELLS AND USES

BIORESTORATIVE THERAPIES,...

1. A human neonatal brown adipose tissue differentiated cell derived from an isolated human neonatal brown adipose tissue stem cell,wherein the isolated human neonatal brown adipose tissue stem cell is grown in a culture medium comprising fibronectin type III domain-containing protein 5 (FNDC5) and differentiates into the human neonatal brown adipose differentiated cell;
wherein UCP-1, ELOVL3, and PGC1A gene expression is upregulated in the human neonatal brown adipose tissue differentiated cell.
US Pat. No. 10,166,177

SILK PROTEIN FRAGMENT COMPOSITIONS AND ARTICLES MANUFACTURED THEREFROM

Silk Therapeutics, Inc., ...

1. A gel comprising a silk protein fragment composition comprising:pure silk fibroin-based protein fragments substantially devoid of sericin and comprising:
an average weight average molecular weight ranging from about 17 kDa to about 38 kDa; and
a polydispersity of between about 1.5 and about 3.0; and
water,
wherein the composition prior to gelation is a solution which does not spontaneously or gradually gelate and does not visibly change in color or turbidity when in the solution for at least 10 days,
wherein the gel includes between 0 ppm and 500 ppm of inorganic residuals, and
wherein the gel includes between 0 ppm and 500 ppm of organic residuals.
US Pat. No. 10,167,459

MODIFIED BETA-FRUCTOFURANOSIDASE FOR FRUCTOOLIGOSACCHARIDE PRODUCTION

STELLENBOSCH UNIVERSITY, ...

1. A modified polypeptide having fructofuranosidase activity, wherein the modified polypeptide comprises an amino acid sequence which is at least 90% identical to SEQ ID NO: 3 and which has at least one amino acid substitution including substitution of the alanine (A) at amino acid position 159 of SEQ ID NO: 3.
US Pat. No. 10,167,462

MODIFIED EL188 ENDOLYSIN SEQUENCE

LYSANDO AG, Triesenberg ...

1. A polypeptide comprising the sequence of SEQ ID NO: 1, wherein SEQ ID NO: 1 is characterized byX1 may be absent or any amino acid,
X120 may be any amino acid,
X126 may be any amino acid,
X128 may be any amino acid,
X134 may be any amino acid,
X135 may be any amino acid,
X138 may be any amino acid,
X171 may be any amino acid,
X173 may be any amino acid,
X182 may be any amino acid,
X187 may be any amino acid,
X197 may be any amino acid,
X198 may be any amino acid,
X204 may be any amino acid,
X230 may be any amino acid,
X231 may be any amino acid,
X234 may be any amino acid, andwherein the polypeptide does neither comprise the amino acid sequence of SEQ ID NO: 2 nor of SEQ ID NO: 183, wherein the polypeptide does not comprise an E155A mutation at position 155 of SEQ ID NO: 1, and wherein X135 is not C.
US Pat. No. 10,167,470

ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSIS

STICHTING KATHOLIEKE UNIV...

1. A method for treating a CEP290-related disease or condition requiring modulating, splicing of CEP290 c.2991+1655A>G, the method comprising administering to a subject in need thereof an exon skipping antisense oligonucleotide that is sufficiently complementary to SEQ ID NO: 6, SEQ ID NO: 7, or SEQ ID NO: 8 to specifically bind to SEQ ID NO:6, SEQ ID NO:7, or SEQ ID NO:8, respectively.
US Pat. No. 10,166,191

SUSTAINED-RELEASE DOSAGE FORMS OF RUXOLITINIB

Incyte Corporation, Wilm...

1. A sustained-release dosage form comprising:(1) about 12.2 wt % ruxolitinib phosphate;
(2) about 20 to about 22 wt % hypromellose;
(3) about 22 to about 42.3 wt % microcrystalline cellulose;
(4) about 20 to about 42.3 wt % lactose monohydrate;
(5) about 1 wt % colloidal silicon dioxide;
(6) about 0.5 wt % magnesium stearate; and
(7) about 2 wt % stearic acid;
wherein administration of said dosage form to a human for at least 16 weeks results in a mean decrease in mean hemoglobin of no more than about 15 g/L or a mean decrease in mean base platelet count of no more than about 100×109/L.
US Pat. No. 10,167,478

REPLICATIVE MINICIRCLE VECTORS WITH IMPROVED EXPRESSION

Nature Technology Corpora...

1. A method of constructing a eukaryotic replicative minicircle expression vector and expressing a gene of interest therefrom comprising:a) combining i) a eukaryotic region with 5? and 3? ends encoding a gene of interest and comprising an intron, the intron comprising a 5? splice donor and a 3? acceptor branch site, a bacterial replication origin selected from the group consisting of R6K replication origin, and ColE2-P9 replication origin, and an RNA selectable marker; with ii) a spacer region linking the 5? and 3? ends of the eukaryotic region, said spacer region being less than 500 basepairs in length, to create a eukaryotic replicative minicircle expression vector; and
b) introducing said replicative minicircle expression vector into a target eukaryotic cell or a eukaryotic organism comprising the target eukaryotic cell, under conditions wherein the target eukaryotic cell is transfected and said gene of interest is expressed.
US Pat. No. 10,167,494

METHOD FOR DETECTION, CHARACTERIZATION AND/OR IDENTIFICATION OF MICROORGANISMS IN A SEALED CONTAINER

bioMerieux, Inc., Durham...

1. A method for detecting and identifying an unknown microorganism that may be present in a test sample, said method comprising:(a) inoculating a specimen container comprising a culture medium with said test sample;
(b) detecting growth of said unknown microorganism in said specimen container using a first spectroscopic technique to obtain at least two time-dependent measurements of a growth composition comprising said sample and correlating said measurements to indicate growth of said unknown microorganism in said culture medium;
(c) subsequently separating said unknown microorganism from said culture medium by centrifugation of said test sample through a homogeneous density cushion to generate a microorganism pellet;
(d) interrogating the microorganism pellet in situ using front face mode intrinsic fluorescence spectroscopy to produce measurements; and
(e) identifying said unknown microorganism in the microorganism pellet to the species level based on the produced intrinsic fluorescence measurements; and
wherein steps (b), (c), and (d) are carried out in a sealed container and wherein said interrogation step (d) is non-invasive.
US Pat. No. 10,167,238

MICRONUTRIENT COMPOSITIONS AND SYSTEMS AND METHODS OF USING SAME

WINFIELD SOLUTIONS, LLC, ...

1. A method of spraying an agricultural spray admixture, comprising:spraying an admixture comprising citric acid and glutamic acid with a metal salt and a pesticide, the pesticide comprising phosphate, the metal salt comprising one or more zinc, boron, copper, iron, chloride, manganese, molybdenum, cobalt, magnesium, calcium, or nickel;
wherein the citric acid glutamic acid and metal salt form a chelate to thereby prevent the metal salt from forming an insoluble solid with the phosphate, and
wherein the citric acid and the glutamic acid are present in the composition at a molar ratio of about 6.8:0.5 to about 1:0.29,
wherein the admixture remains stable, non-precipitated for at least 72 hours.
US Pat. No. 10,167,248

PROCESS FOR THE REDUCTIVE AMINATION AND SELECTIVE HYDROGENATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN

Taminco BVBA, Ghent (BE)...

1. A process for the reductive amination of a halo-benzaldehyde in the presence of a nitrogen containing compound, wherein the halogen atom is selected from the list consisting of chlorine, bromine, iodine, and combinations thereof, in the presence of hydrogen and a heterogeneous catalyst supported on carbon, said heterogenous catalyst comprising at least one first metal comprising palladium, rhodium, or ruthenium, together with at least one second metal comprising silver, nickel, cobalt, tin, copper, or gold.
US Pat. No. 10,167,251

4-(P-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES

BIOELECTRON TECHNOLOGY CO...

1. A compound selected from the group consisting of 2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide and 2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide as its hydroquinone form; and salts, stereoisomers, and mixtures of stereoisomers thereof.
US Pat. No. 10,167,518

METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS

Syros Pharmaceuticals, In...

1. A method of diagnosing and treating a human subject suffering from myelodysplastic syndrome (MDS), the method comprising:a. diagnosing whether the subject has a tamibarotene-sensitive form of the MDS based on a level of retinoic acid receptor alpha (RARA) mRNA previously determined to be present in a sample of diseased cells from the subject, wherein the RARA mRNA is transcribed from a RARA gene that encodes a functional retinoic acid receptor-? and specifically excludes gene fusions that comprise all or a portion of the RARA gene; and
b. administering to the subject an amount of tamibarotene effective to treat the MDS,
wherein the level of RARA mRNA is equal to or above a predetermined threshold.
US Pat. No. 10,166,240

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS

Imprimis Pharmaceuticals,...

1. A method for inducing conscious sedation comprising orally administering to a patient in need thereof a pharmaceutical composition comprising:(a) a therapeutically effective quantity of a first pharmaceutically active compound selected from the group consisting of midazolam, diazepam, lorazepam, flunitrazepam, alprazolam, chlordiazepoxide, clonazepam and clorazepate, and pharmaceutically acceptable salts, hydrates, solvates or N-oxides thereof;
(b) a therapeutically effective quantity of a second pharmaceutically active compound selected from the group consisting of ketamine, dextrorphan, etomidate, methadone, memantine, amantadine, dextromethorphan, and pharmaceutically acceptable salts, hydrates, solvates or N-oxides thereof;
(c) a pharmaceutically suitable binder therefor; and
(d) optionally, a pharmaceutically acceptable excipient,
wherein the pharmaceutical composition is formulated as a solid item adapted for sublingual or buccal administration, the solid item being selected from the group consisting of a troche, a lozenge, a capsule, a pill, a cap, and a bolus,
thereby inducing conscious sedation in the patient.
US Pat. No. 10,167,524

VIRUS CAUSING RESPIRATORY TRACT ILLNESS IN SUSCEPTIBLE MAMMALS

Erasmus University Medica...

1. A kit for determining the presence of metapneumovirus (MPV) in a mammalian subject, the kit comprising:a DNA probe of at least 10 nucleotides that hybridizes under stringent conditions to a target polynucleotide,
wherein the target polynucleotide is a contiguous portion of a sequence encoding a polypeptide that is at least 90% identical to SEQ ID NO:8 or the complement of the sequence, and
wherein the DNA probe does not hybridize under stringent conditions to a polynucleotide from avian pneumovirus (APV).
US Pat. No. 10,166,245

ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES

Cassiopea S.P.A., Lainat...

1. Crystalline form I of cortexolone-17?-propionate characterized by:a DRX as shown in FIG. 1; or
a DRX with at least peaks at about: 7.6, 8.4, 14.3, 14.8, 15.7, 17.0, and 20.1 degrees 2theta.
US Pat. No. 10,165,744

INBRED CORN LINE KM5

Limagrain Europe, S.A., ...

1. A seed of inbred corn line designated KM5, wherein a representative sample of seed of said line was deposited under ATCC Accession No. PTA-125125.
US Pat. No. 10,168,318

METHOD OF MEASURING CELL-SUBSTRATE IMPEDANCE IN LIVING CELLS TO IDENTIFY COMPOUNDS AFFECTING RECEPTOR TYROSINE KINASE (RTK) ACTIVITY AND PATHWAYS

ACEA Biosciences, Inc., ...

1. A method of identifying a potential therapeutic compound that affects a Receptor Tyrosine Kinase (RTK) pathway in cancer cells, the method comprising:a) providing a device capable of measuring cell-substrate impedance, wherein the device comprises at least two wells, each well comprising an electrode array, further wherein the device is operably connected to an impedance analyzer;
b) culturing cells embodied as cancer cells in serum-free media in the at least two wells;
c) adding to a first well a proposed therapeutic compound that affects an RTK pathway and an RTK stimulating factor for the RTK pathway to form a test well, and adding to another well the RTK stimulating factor to form a control well;
d) continuously monitoring cell-substrate impedance of the at least two wells and optionally determining cell indices from the monitored cell-substrate impedance; and
e) determining a difference in impedance or optionally in cell index between the test well and control well; and if significantly different,
f) concluding the proposed therapeutic compound is therapeutically active in the RTK pathway within the cancer cells.
US Pat. No. 10,166,270

COMPOSITION AND METHOD FOR AFFECTING CYTOKINES AND NF-?B

Zivo Bioscience, Inc., K...

1. A method of treating inflammation in a subject in need thereof; the method comprising administering to said subject an effective amount of phyto-percolate derived from culturing microorganisms of ATCC Deposit #PTA-5863 wherein the inflammation is treated by the phyto-percolate up regulating anti-inflammatory cytokines while down regulating pro-inflammatory cytokines.
US Pat. No. 10,166,271

METHODS FOR PROMOTING HAIR GROWTH

THE REGENTS OF THE UNIVER...

1. A method for promoting hair growth in a subject, comprising:administering to a subject having a decrease in the number of hair follicles in the anagen phase an effective amount of a cyclic peptide non-selective antagonist of corticotrophin release factor (CRF) receptors 1 and 2 that increases the number of hair follicles in the anagen phase, wherein the antagonist is astressin B and administration is by subcutaneous, intraperitoneal, topical or transdermal delivery;
increasing the number of hair follicles in the anagen phase; and
promoting hair growth in the subject.
US Pat. No. 10,166,279

VACCINE

The Administrators of the...

1. A mutant of an E. coli heat-stable toxin (ST) having the following wild-type sequence:NSSNYCCELCCNPACTGCY (SEQ ID NO: 1)
wherein the mutant has one or two mutations, and wherein the mutant comprises a mutation selected from the group consisting of: A14T and N12T.
US Pat. No. 10,168,332

METHOD FOR PREDICTING PROGNOSIS OF ACUTE MYELOID LEUKEMIA RELAPSE

The Catholic University o...

1. A method for selecting treatment for an acute myeliod leukemia (AML) patient, comprising:i) obtaining a bone marrow sample from said leukemia patient following complete remission from acute myeloid leukemia;
ii) assaying cells of said bone marrow sample to determine levels of stromal cells selected from the group consisting of primitive mesenchymal stromal cells, differentiated mesenchymal stromal cells and osteoblastic cells;
iii) referring patients having increased levels of primitive mesenchymal stromal cells in said sample compared to levels of primitive mesenchymal stromal cells of a healthy, leukemia-free individual for anti-AML treatment, and/or
iv) referring patients having increased levels of differentiated mesenchymal stromal cells and/or osteoblastic cells in said sample compared to levels of differentiated mesenchymal stromal cells and/or osteoblastic cells of a healthy, leukemia-free individual for anti-AML treatment.
US Pat. No. 10,167,316

ANTI-CANCER PEPTIDE AND USE THEREOF

ENSOL BIOSCIENCES INC., ...

1. A peptide consisting of the amino acid sequence of SEQ ID NO: 1 or a pharmaceutically acceptable salt thereof.
US Pat. No. 10,166,293

REDUCED-VISCOSITY CONCENTRATED PROTEIN FORMULATIONS

Genentech, Inc., South S...

1. A stable liquid formulation comprising a protein in an amount of at least about 80 mg/ml and a pharmaceutically acceptable acid, base or buffer in an amount of at least about 50 mM, so as to have either a pH of about 4.2 to about 4.9 or about 7.1 to about 12.0 and having a kinematic viscosity of about 50 cs or less at 25° C.
US Pat. No. 10,165,790

METHOD FOR CONDUCING CONCENTRATED CANNABIS OIL TO BE STABLE, EMULSIFIABLE AND FLAVORLESS FOR USE IN HOT BEVERAGES AND RESULTING POWDERIZED CANNABIS OIL

PIVOT NATURALS, LLC, Ana...

1. A method for making powderized cannabis oil consisting essentially of:selecting a cannabis oil with a desired concentration of THC;
measuring a desired quantity of the cannabis oil;
measuring a desired quantity of a maltodextrin to achieve a ratio of the maltodextrin to the cannabis oil, by weight;
wherein the ratio of the maltodextrin to the cannabis oil, by weight, is at least three grams of maltodextrin to every one-half of a gram of cannabis oil; and
mixing the cannabis oil and the maltodextrin until the cannabis oil is evenly absorbed by the maltodextrin.
US Pat. No. 10,165,791

USE OF RUBUSOSIDE FOR REDUCING OR SUPPRESSING CERTAIN UNPLEASANT TASTE IMPRESSIONS

Symrise AG, Holzminden (...

1. A method for masking the sour and/or astringent taste of a substance selected from the group consisting of quercitrin, gallic or ellagic acid esters of carbohydrates, pentagalloylglucose, galloylated catechins, galloylated epicatechins, proanthocyanidins, procyanidins, thearubigenin, and mixtures thereof, wherein the method is consisting of:adding to said substance, an amount of rubusoside that does not bring about a sweet taste impression that is greater than a sweet taste impression of a 1.5 wt. % aqueous sucrose solution, thereby masking sour and/or astringent taste of the substance.
US Pat. No. 10,167,352

POLYMERIZATION INITIATING SYSTEM AND METHOD TO PRODUCE HIGHLY REACTIVE OLEFIN FUNCTIONAL POLYMERS

University of Massachuset...

1. A process for the preparation of polybutene having an exo-olefin content of at least 50 mol. % from an impure isobutene or an isobutene-containing monomer feedstock containing from about 5 ppm to about 500 ppm of polar impurities, which process comprises contacting said impure isobutene or isobutene-containing feedstock, with a Lewis acid catalyst complexed with a Lewis base, in a substantially or completely apolar polymerization medium, and initiating polymerization of said isobutene or isobutene-containing feedstock with an initiator, wherein said Lewis acid catalyst is a Lewis acid of the formula R?AlCl2, wherein R? is a hydrocarbyl group; said Lewis base is a dihydrocarbyl ether wherein each hydrocarbyl group is independently selected from hydrocarbyl groups having 1 to 8 carbon atoms and one or both hydrocarbyl groups of the dihydrocarbyl ether are substituted with an electron withdrawing group and the initiator is a compound of the formula RX, wherein X is a halide; R is a hydrocarbyl group capable of forming a stable carbocation, and wherein the carbon linking group R to group X is tertiary, benzylic or allylic; wherein the amount of water in said feedstock is controlled to be between an amount at least equal to the molar amount of polar impurities in said feedstock, and less than 5 mM per liter of feedstock.
US Pat. No. 10,167,363

MODIFIED POLYBUTYLENE NAPHTHALATE FOR IMPROVED PERFORMANCE AND PROCESS OF MAKING THEREOF

Ester Industries Limited,...

1. A polybutylene naphthalate polyester having haze value less than 7 NTU comprising:naphthalate dicarboxylic acid or ester thereof; butane diol; crystallization suppressing agent in an amount of 1 to 20 wt % based on total weight of the polyester; agent selected from the group consisting of liquid plasticizer in an amount of 0.5 wt % to 2 wt %; nucleating agent in an amount of 10 ppm to 2000 ppm; branching agent in an amount of 10 ppm to 2000 ppm; anti-oxidizing agent in an amount of 0.1 wt % to 5 wt %; stabilizing agent; additive and optionally, end capped oligomer in an amount of 1 to 20 wt %, wherein said polyester exhibits one or more properties as follows:
color L* range is greater than 50;
color b* ranges from 1 to 15;
monoethylene content of less than 10%;
glass transition temperature in the range of 60° C. to 85° C.; and
haze value less than 7 NTU.

US Pat. No. 10,172,112

CORE NETWORK NODE AND METHOD—TIME COORDINATED CELLS FOR EXTENDED DISCONTINUOUS RECEIVE (EDRX)

Telefonaktiebolaget LM Er...

1. A core network (CN) node configured to interact with a plurality of radio access network (RAN) nodes to time coordinate a plurality of cells and maintain a reliability of paging a wireless device, the CN node comprising:a processor; and,
a memory that stores processor-executable instructions, wherein the processor interfaces with the memory to execute the processor-executable instructions, whereby the CN node is operable to:
transmit a paging request to one of the RAN nodes, wherein the paging request includes information associated with the wireless device, the information for using by the one RAN node to calculate a time remaining until a next paging opportunity for the wireless device within the cells comprising a paging area of the wireless device, and wherein the information comprises an International Mobile Subscriber Identity (IMSI) of the wireless device, an extended Discontinuous Receive (eDRX) cycle length of the wireless device, and a coverage class of the wireless device; and,
receive a paging response from the one RAN node, wherein the paging response includes the time remaining until a next paging opportunity for the wireless device.

US Pat. No. 10,172,101

NETWORK NODES, A WIRELESS DEVICE AND METHODS THEREIN FOR ENABLING TRANSMISSIONS IN A WIRELESS COMMUNICATIONS NETWORK

Telefonaktiebolaget LM Er...

1. A method performed by a second network node for performing a transmission in a wireless communications network, wherein the second network node and at least one first network node in the wireless communications network performs transmissions using contention-based transmission resources of the same frequency, the method comprising:obtaining indications of a maximum transmit power associated with two or more first network nodes;
determining a single overall indication of a first maximum transmission power for the transmission based on the obtained indications of the maximum transmit power associated with the two or more first network nodes; and
performing the transmission based on the first maximum transmission power when the contention-based transmission resources of the same frequency is available for transmissions by the at least one first network node in the wireless communications network.

US Pat. No. 10,172,090

SENSOR HEADROOM CONTROL CIRCUIT

InvenSense, Inc., San Jo...

1. A sensor headroom control circuit comprising:a front end analog circuit having configurable headroom and configured to receive a sensor input signal and output a sensor digital signal;
a digital compensation circuit configured to adjust the sensor digital signal to compensate for an active headroom state of the front end analog circuit and produce a compensated sensor signal; and
a headroom state selection circuit configured to select the active headroom state of the front end analog circuit responsive to a detected level of the compensated sensor signal.

US Pat. No. 10,172,057

HANDLING OF RADIO ACCESS NETWORK RE-SELECTION

TELEFONAKTIEBOLAGET LM ER...

1. A method of operation by a Circuit Switched (CS) control node performed with respect to a UE that switched from a Packet Switched (PS) connection to a CS connection for execution of a CS service, the method comprising:determining that the UE is capable of connecting to a PS RAN that provides PS service coverage for a current geographic location of the UE; and
in response to receiving an indication that the CS service shall be terminated:
generating a message that indicates one or more radio parameters of the PS RAN, to assist the UE in reselecting from the CS RAN to the PS RAN upon termination of the CS service; and
using Non-Access Stratum (NAS) signaling to send the message to the UE over the CS connection, such that the message passes transparently through a CS RAN that provides the CS connection.

US Pat. No. 10,172,049

NETWORK NODE AND METHOD THEREIN FOR HANDOVER IN WIRELESS COMMUNICATION NETWORK

TELEFONAKTIEBOLAGET LM ER...

1. A method performed in a network node for assisting a communication device to perform handover from a serving cell to a target cell in a communication network, wherein the network node is a serving node for the communication device in the serving cell, the method comprising:obtaining a first round trip time between the network node and a server;
obtaining a second round trip time between a target node in the target cell and the server;
deciding whether or not to instruct the communication device to perform handover from the serving cell to the target cell by considering at least the first round trip time and the second round trip time; and
conditionally instructing the communication device to perform handover from the serving cell to the target cell in accordance with the decision,
wherein deciding whether or not to instruct the communication device to perform handover from the serving cell to the target cell comprises:
deciding if the first round trip time is longer than the second round trip time, and if so then deciding to perform handover from the serving cell to the target cell.

US Pat. No. 10,172,022

DIAGNOSTIC ANALYZER FOR CONTENT RECEIVER USING WIRELESS EXECUTION DEVICE

Pearson Education, Inc., ...

1. A wireless interactive diagnostic system comprising a diagnostic analyzer server, an interactive content execution device, and one or more interactive content receiver devices:each of the one or more interactive content receiver devices comprising:
a processing unit comprising one or more processors;
a wireless network interface;
an input/output (I/O) subsystem configured to receive input data via one or more input devices connected to or integral with the interactive content receiver device; and
memory coupled with and readable by the processing unit and storing therein a set of instructions which, when executed by the processing unit, causes the interactive content receiver device to:
establish a wireless connection to the interactive content execution device via the wireless network interface;
receive diagnostic modules of interactive content from the interactive content execution device via the wireless network interface;
output the diagnostic modules of interactive content via the I/O subsystem;
receive input data via the I/O subsystem corresponding to responses to the interactive content; and
transmit the responses to the interactive content to interactive content execution device via the wireless network interface;
the interactive content execution device comprising:
a processing unit comprising one or more processors;
a plurality of network interfaces;
an input/output (I/O) subsystem configured to receive input data via one or more input devices connected to or integral with the interactive content receiver device; and
memory coupled with and readable by the processing unit and storing therein a set of instructions which, when executed by the processing unit, causes the interactive content execution device to:
establish wireless connections with the one or more interactive content receiver devices via a first network interface of the plurality of network interfaces;
receive selections via the I/O subsystem of diagnostic modules for execution on particular interactive content receiver devices;
in response to receiving selections of diagnostic modules via the I/O subsystem, retrieve the selected diagnostic modules from the diagnostic analyzer server via a second network interface;
initiate execution of selected diagnostic modules retrieved from the diagnostic analyzer server;
perform repeatedly during execution of the selected diagnostic modules:
identifying and transmitting particular interactive content within particular diagnostic modules to particular interactive content receiver devices via the first network interface; and
receiving responses to the particular interactive content via the first network interface;
after the execution of the selected diagnostic modules, determine performance measurements for the diagnostic modules based on the received responses to the particular interactive content;
transmit the determined performance measurements for an initial set of diagnostic modules to the diagnostic analyzer server via a second network interface;
receive selections of one or more subsequent diagnostic modules, from the diagnostic analyzer server, based on the performance measurements of the initial set of diagnostic modules; and
output the selections via the I/O subsystem of the subsequent diagnostic modules for particular interactive content receiver devices;
the diagnostic analyzer server comprising:
a processing unit comprising one or more processors; and
memory coupled with and readable by the processing unit and storing therein a set of instructions which, when executed by the processing unit, causes the diagnostic analyzer server to:
receive requests for diagnostic modules from the interactive content execution device, said requests associated with particular interactive content recipients;
in response to requests for diagnostic modules received from the interactive content execution device, retrieve the requested diagnostic modules from an interactive content data store and transmit the requested diagnostic modules to the interactive content execution device;
receive sets of performance measurements from the interactive content execution device, each said set of performance measurements corresponding to responses from a particular interactive content recipient to one or more diagnostic modules; and
in response to a particular set of received performance measurements associated with a particular interactive content recipient:
retrieving previously collected entity records associated with the particular interactive content recipient;
determining one or more subsequent diagnostic modules for the particular interactive content recipient, based on the particular set of received performance measurements and the previously collected entity records associated with the particular interactive content recipient; and
transmit the one or more subsequent diagnostic modules for the particular interactive content recipient, to the interactive content execution device.

US Pat. No. 10,172,018

WIRELESS SYSTEMS AND METHODS USING MILLIMETER WAVE BAND SIGNALS WITH ASYMMETRIC DIRECTIVITY

Phazr, Inc., Allen, TX (...

1. A wireless communication system using asymmetric directivity signals, comprising:a base station configured to transmit millimeter wave band low directivity downlink signals having a wide beamwidth in separate time slots in a shared frequency channel;
a plurality of communication devices configured to receive the millimeter wave band low directivity downlink signals in the shared frequency channel;
the plurality of communication devices each configured to transmit millimeter wave band high directivity uplink signals having narrow beamwidth in different respective frequency channels,
the base station configured to receive the millimeter wave band high directivity uplink signals having narrow beamwidth in the respective frequency channels.

US Pat. No. 10,172,017

METHOD AND APPARATUS FOR ASSIGNING CELL IDENTIFIER VALUES AND METHOD AND APPARATUS FOR MANAGING ASSIGNMENT OF CELL IDENTIFIER VALUES IN A COMMUNICATION NETWORK

Telefonaktiebolaget LM Er...

1. A method of assigning cell identifier values for cells within a border area in a communication network, the method comprising the steps of:selecting an identified frequency for identifying the border area in the communication network;
selecting a first managed cell set in the border area, wherein the first managed cell set is one of at least two managed cell sets within the border area that comprises the first managed cell set and at least one other managed cell set, and wherein each of the at least two managed cell sets is managed by a different one of at least two Operation Support Systems;
obtaining a set of candidate cell identifier values of each respective one of the at least one other managed cell set, wherein for each obtained set of candidate cell identifier values, each of the candidate cell identifier values in the obtained set is a cell identifier value that is available for assignment to a cell associated with the respective one of the at least one other managed cell set without conflicting with any cell identifiers assigned to border area cells of the at least one other managed cell set, wherein a cell identifier value is in conflict with another cell identifier value if the cell identifier value is the same as the cell identifier value of a neighboring cell or is the same as the cell identifier value of a cell that is neighboring the neighboring cell;
identifying as suitable cell identifier values for the first managed cell set, cell identifier values that are common among the sets of candidate cell identifier values for the at least one other managed cell set;
assigning a set of the suitable cell identifier values to the first managed cell set by providing the set of suitable cell identifier values to the Operation Support System that manages the first managed cell set;
updating the set of candidate cell identifier values based on the assigned set of suitable cell identifier values; and
selecting another one of the at least two managed cell sets within the border area and repeating the steps of the method until all of the managed cell sets within the border area have cell identifier values assigned.

US Pat. No. 10,172,010

ENHANCEMENTS FOR OPERATOR SPECTRUM SHARING

Nokia Solutions and Netwo...

1. A method comprising:receiving, at a first cell, radio resource information from a second cell, said first and second cells in at least one network controlled by two or more operators;
receiving operator identity information and cell-type information at said first cell from said second cell;
storing, at the first cell, said radio resource information, said operator identity information, and said cell-type information in at least one of a radio resource allocation table (RRAT) and a background interference matrix (BIM), wherein at least one of said RRAT and BIM comprise a first field for signifying said cell-type information and a second field for signifying said operator identity information; and
allocating radio resources shared between the first cell and the second cell in dependence on at least one of said RRAT and said BIM.

US Pat. No. 10,171,995

AUTOMATED CREDENTIAL PORTING FOR MOBILE DEVICES

Headwater Research LLC, ...

1. A method performed by a network system communicatively coupled to a wireless device by a wireless access network, the method comprising:receiving, from the wireless device, a request to replace a current phone number of the wireless device with a second phone number;
based on the current phone number and the second phone number, initiating a network-provisioning state change;
sending a message to the wireless device, the message indicating the network-provisioning state change;
receiving a request from the wireless device to initiate a programming session,
establishing a programming session with the wireless device;
obtaining an updated phone number from a database, the updated phone number associated with the wireless device;
provisioning one or more network elements in accordance with the updated phone number; and
sending the updated phone number to the wireless device.

US Pat. No. 10,171,973

METHOD AND SYSTEM FOR MTC EVENT MANAGEMENT

HUAWEI TECHNOLOGIES CO., ...

1. A method for management of a Machine Type Communication (MTC) event, the method comprising:receiving, by an Event Management Entity (EME), data indicative of an event context of the MTC event, the event context indicative of classification and correlation of the MTC event; and
transmitting, by the EME, a VNF state change trigger upon determination that a change in state of a Virtual Network Function (VNF) positioned in proximity and configured to utilize VNF resources to mitigate the MTC event is required.

US Pat. No. 10,171,963

CALL TRANSFER METHOD AND TERMINAL

HUAWEI TECHNOLOGIES CO., ...

1. A call transfer method, comprising:sending, by a first terminal, a local number query request to a second terminal using a near field communication link, wherein the local number query request requests the second terminal to query a local number of the second terminal;
receiving, by the first terminal, the local number of the second terminal from the second terminal; and
sending, by the first terminal, a call transfer request to a network side according to the local number of the second terminal, wherein the call transfer request requests the network side to update a call transfer target of the first terminal to the local number of the second terminal, and
wherein after sending, by the first terminal, the call transfer request to the network side, the method further comprises:
detecting, by the first terminal according to a preset period, whether the near field communication link established between the first terminal and the second terminal is valid, wherein valid means that near field communication manner is available and ca be used to transmit data; and
sending, by the first terminal, a second call transfer request to the network side when the near field communication link established between the first terminal and the second terminal is invalid, wherein the second call transfer request requests that the network side update the call transfer target of the first terminal to a preset local number.

US Pat. No. 10,171,960

MOBILE TERMINAL AND PROCESSOR

KYOCERA Corporation, Kyo...

1. A broadcast multicast service center (BM-SC) included in a system for mobile communication, the system including a general cell that supports broadcast delivery of Multimedia Broadcast Multicast Services (MBMS) data and a specific cell that does not support broadcast delivery of MBMS data, the BM-SC comprising:a processor; and
a memory communicatively coupled to the processor, wherein
the processor is configured to transmit, via the specific cell, first information to mobile terminal located in the specific cell, the first information originally transmitted in a transmission path that does not include the general cell, the transmission path being from the BM-SC to the user terminal, wherein
the first information is for receiving MBMS data and comprises:
information indicating a geographical area in which the MBMS data is delivered;
information indicating a frequency at which the MBMS data is delivered; and
information indicating an identifier of service by which the MBMS data is provided.

US Pat. No. 10,171,935

HEALTHCARE PROXIMITY SERVICES

MicroStrategy Incorporate...

1. A computer-implemented method comprising:receiving, from an application instance operating on a first client device, information indicating (i) a patient identifier corresponding to a patient associated with the first client device, (ii) a beacon identifier associated with a wireless proximity beacon that is associated with a physical location within a healthcare facility, and (iii) a proximity of the first client device to the wireless proximity beacon associated with the beacon identifier;
estimating a physical location of the first client device within the healthcare facility based at least on (i) the beacon identifier associated with the wireless proximity beacon, and (ii) the proximity of the first client device to the wireless proximity beacon;
accessing a patient profile associated with the patient identifier, the patient profile comprising patient information corresponding to the patient;
receiving, from each of one or more application instances that operate on one or more respective second client devices associated with one or more healthcare providers of the healthcare facility, (i) a beacon identifier associated with a wireless proximity beacon that is associated with a physical location within a healthcare facility, and (ii) a proximity of the second client device associated with the healthcare provider to the wireless proximity beacon associated with the beacon identifier;
estimating, for each of the one or more second client devices associated with the one or more healthcare providers, a physical location of the second client device associated with the healthcare provider within the healthcare facility based at least on (i) the beacon identifier associated with the wireless proximity beacon, and (ii) the proximity of the second client device associated with the healthcare provider to the wireless proximity beacon associated with the beacon identifier;
selecting, from among the one or more second client devices associated with the one or more healthcare providers, a particular second client device associated with a particular healthcare provider based at least on the estimated physical location of the first client device and the estimated physical locations of the one or more second client devices associated with the one or more healthcare providers; and
transmitting, to the particular second client device associated with the particular healthcare provider, at least a portion of the patient information for display at an interface of the particular second client device associated with the particular healthcare provider.

US Pat. No. 10,171,934

EFFICIENT GEO-FENCE DATA TRANSFER AND NOTIFICATIONS USING A TIME TO REACH VALUE

eBay Inc., San Jose, CA ...

1. A method comprising:accessing a current location of a client system;
identifying a plurality of geo-fences based on the current location of the client system;
receiving movement path data from the client system;
determining an average travel speed for the client system;
identifying a mode of travel for a user associated with the client system based on at least the average travel speed and the movement path data;
calculating a predicted travel route to each geo-fence in the plurality of geo-fences based on the current location of the client system and the identified mode of travel, the calculating of the predicted travel route for at least one geo-fence in the plurality of geo-fences including:
identifying at least one obstacle on the predicted travel route;
based on the identified mode of travel, determining whether the identified mode of travel by which the client system is traveling would be able to traverse the identified at least one obstacle;
in accordance with a determination that the identified mode of travel by which the client system is traveling would be unable to traverse the at least one obstacle, calculating the predicted travel route such that the at least one obstacle is avoided;
calculating a time to reach of the client system to each of the plurality of geo-fences based on the predicted travel route and the mode of travel, the time to reach indicating an arrival time to each of the plurality of geo-fences;
ranking the plurality of geo-fences based on the time to reach of each geo-fence of the plurality of geo-fences;
selecting a target geo-fence from the plurality of geo-fences based on a ranking of the target geo-fence in the plurality of geo-fences, the target geo-fence having a corresponding notification range, the corresponding notification range defining a time period within which notifications are to be presented at the client system, the time period comprising an earliest notification value and a latest notification value, such that no notification is generated before the earliest notification value and no notification is generated after the latest notification value;
determining that the arrival time of the client device to the target geo-fence is within the time period defined by the corresponding notification range; and
in accordance with the determination that the time to reach value associated with the target geo-fence is less than or equal to the notification range, presenting a notification that identifies the target geo-fence at the client system.

US Pat. No. 10,171,918

MEMS MICROPHONE MODULES AND WAFER-LEVEL TECHNIQUES FOR FABRICATING THE SAME

Heptagon Micro Optics Pte...

1. A module comprising:a MEMS microphone module including:
a first substrate;
a second substrate on which is mounted a MEMS microphone device, wherein the second substrate is separated from the first substrate by a first spacer;
an integrated circuit device mounted on the first substrate and arranged to perform processing of signals from the MEMS microphone device; and
a cover separated from the second substrate by a second spacer;
an opening in the cover or in the second spacer through which sound can enter; and
a second module joined to the MEMS microphone module, wherein the second module and the MEMS microphone module are side-by-side, and wherein interior regions of the second module and the MEMS microphone module are separated from one another by the first and second spacers.