US Pat. No. 10,427,035

GAME CONTROLLER WITH REMOVABLE TRIGGER ACCESSORY

MICROSOFT TECHNOLOGY LICE...

1. A game controller, comprising:a trigger-activation sensor;
a sensor-activation feature moveable relative to the trigger-activation sensor, wherein the trigger-activation sensor outputs a control signal based on a relative position of the sensor-activation feature and the trigger-activation sensor; and
a mounting platform including a trigger-retention feature configured to removably affix a selected removable trigger accessory to the mounting platform, the selected removable trigger accessory being one of a plurality of differently configured removable trigger accessories removably affixable to the mounting platform, the selected removable trigger accessory configured to change the relative position of the sensor-activation feature and the trigger-activation sensor based on finger manipulation of the selected removable trigger accessory when the selected removable trigger accessory is removably affixed to the mounting platform, and the mounting platform being configured to move with the selected removable trigger accessory responsive to finger manipulation of the selected removable trigger accessory when the selected removable trigger accessory is affixed to the mounting platform.

US Pat. No. 10,427,034

CONTACTLESS TACTILE FEEDBACK ON GAMING TERMINAL WITH 3D DISPLAY

IGT Canada Solutions ULC,...

1. An electronic gaming machine for providing a game to a player, the electronic gaming machine comprising:a display having a display surface,
a locating sensor generating an electronic signal based on a player's location in a three dimensional sensing space, the sensing space including a region adjacent to the display surface;
an ultrasonic emitter to emit an ultrasonic field when the ultrasonic emitter is activated, at least a portion of the ultrasonic field being located in the three dimensional sensing space, the ultrasonic field providing a pressure differential detectible by a human hand, the ultrasonic emitter located above, below, to the left or right of the three dimensional sensing space; and
a processor coupled to the display, the locating sensor and the ultrasonic emitter, the processor to:
identify a location of a player feature within the three dimensional sensing space based on the electrical signal from the locating sensor;
determine that a hand of the player has virtually contacted an interface element provided in the game based on the location of the player feature within the three dimensional sensing space; and
in response to determining that the player has virtually contacted the interface element, control the ultrasonic emitter based on the identified location to emit the ultrasonic field providing the pressure differential at the identified location to provide tactile feedback to the player to allow the player to feel a weight of the interface element on their hand.

US Pat. No. 10,427,033

DISPLAY CONTROL APPARATUS AND DISPLAY CONTROL METHOD

Sony Interactive Entertai...

1. A display control apparatus comprising:a position control section adapted to control a position of an object arranged in a virtual three-dimensional space based on a relative position between an input apparatus used by a user wearing a head-mounted display and the head-mounted display; and
a display control section adapted to generate an image in the virtual three-dimensional space including the object and display the image on the head-mounted display, wherein
when a distance between the input apparatus and the head-mounted display is equal to a first distance or more, the position control section linearly changes the object position in response to a change in position of the input apparatus, and
when the distance between the input apparatus and the head-mounted display is less than the first distance, the position control section determines the object position in accordance with a criterion different from that used when the distance between the input apparatus and the head-mounted display is equal to the first distance or more.

US Pat. No. 10,427,030

CUSTOMIZABLE DISPLAY OF BETTING LAYOUT

IGT, Las Vegas, NV (US)

1. A gaming system comprising:a housing;
a display device supported by the housing;
a plurality of input devices supported by the housing, the plurality of input devices comprising:
an acceptor of a first physical item associated with a first monetary value,
a validator configured to identify the first physical item, and
a cashout device configured to receive an input to cause an initiation of a payout associated with a player credit balance;
a processor; and
a memory device that stores a plurality of instructions which, when executed by the processor, cause the processor to:
cause, via the display device, a display of the player credit balance;
cause, via the display device, a display of a first betting layout comprising a first plurality of different bet options that are each player selectable via one of the input devices for a play of a game;
receive, via one of the input devices, an input from a player, said received input identifying a player selected one of the displayed first plurality of bet options to delete;
store data representing a second different betting layout in the memory device, the second different betting layout comprising a second plurality of different bet options that are each player selectable via one of the input devices for the play of the game, said second plurality of bet options comprising the first plurality of different bet options except for the bet option the player selected to delete;
use the stored data to display, via the display device, the second different betting layout;
receive, via one of the input devices, an input from the player, said received input selecting one of the second plurality of bet options for the play of the game;
cause, via the display device, a display of a video representation of the play of the game received by the gaming system via a data network; and
responsive to the bet option selected by the player being a winning outcome based on the play of the game, increasing the player credit balance.

US Pat. No. 10,427,029

SMART BIN LOTTERY TICKET DISPENSER WITH MODULAR PRINTER BIN

Scientific Games Internat...

1. A lottery ticket dispenser array, comprising:a plurality of separate bins arranged within a frame, each bin defined by a housing having a front side that faces a purchaser in operational use of the dispenser array, an opposite back side, and an internal space for receipt of a supply of interconnected lottery tickets, wherein each lottery ticket contains a code printed thereon;
each bin having an electronic drive mechanism that dispenses the lottery tickets therefrom;
wherein the bins are separately removable and insertable into the array; and
a printer module having a size and configuration so as to be insertable into the array in place of at least one of the bins.

US Pat. No. 10,427,028

TILES ON SHAPES PUZZLE GAME

1. A tile-on-shape puzzle game comprising:at least one tile, wherein the at least one tile is either a first tile design or a second tile design;
wherein the first tile design further comprises:
an upper face;
a plurality of edges, where the plurality of edges is at least three linear edges, curved edges, or combination of linear edges and curved edges;
a lower face;
a play indicia disposed on the upper face;
wherein the second tile design further comprises:
an upper face;
a plurality of edges, where the plurality of edges is at least three linear edges, curved edges, or combination of linear edges and curved edges;
a lower face;
a play indicia disposed on the upper face;
at least one projection extending from the lower face;
a plurality of playing shapes, further comprising:
a shape surface having a first face and a second face;
a plurality of shape edges, where the plurality of shape edges is at least three linear edges, circumferential edges, or combination of linear edges and circumferential edges;
a plurality of sides, wherein the plurality of sides have a width smaller than the width of the first face;
at least one recess disposed on the first face, wherein the recess is complementary to the at least one tile of the first tile design or a projection extending from the at least one tile of the second tile design;
wherein the at least one recess has at least three linear edges, octagonal edges, circumferential edges, or combination of linear edges and circumferential edges;
wherein the at least one recess is dimensioned such that the at least one tile or the projection extending from the at least one tile is accepted within the at least one recess; and
at least one inverse tile recess disposed on the second face of the playing shapes and corresponding to the inverse location of the at least one recess on the at least one shape disposed on the first face;
wherein the at least one inverse tile recess has at least three linear edges, octagonal edges, circumferential edges, or combination of linear edges and circumferential edges;
wherein at least two of the edges of the recess are parallel to each other; and
wherein the at least one inverse recess is dimensioned such that the at least one tile or the projection extending from the at least one tile is accepted within the at least one inverse tile recess.

US Pat. No. 10,427,027

CASINO TABLE GAME APPARATUS AND METHOD

1. A method of playing a dice game comprising:providing a dice cup with a flat base and substantially flat upper surface to the base;
providing a first pair of cubic dice with first and second die, with the first and second die of the first pair of cubic dice each having six flat sides and eight corresponding corners and each flat side of the first and second die having a marking to indicate a unique integer value from one to six;
providing a second pair of cubic bonus dice with first and second die, with the first and second die of the second pair of cubic bonus dice each having six flat sides and eight corresponding corners, the first die having five flat sides with no markings and one flat side with a “Y” marking, and the second die having five flat sides with no markings and one flat side with a “O” marking;
providing a designated game surface identified as a gaming layout or a dice landing tray with six designated point areas and corresponding markings for the numbers 4, 5, 6, 8, 9, and 10;
providing a dealer; and
providing at least one player;
wherein the method comprising the steps of:
(a) placing a play wager by each player;
(b) presenting the dice cup containing the first pair of cubic dice and the second pair of cubic bonus dice from the dealer to one player designated as a shooter;
(c) use of the dice cup by the shooter, prior to establishment of a number comparison point, to make a pre-point roll of the first pair of cubic dice and the second pair of cubic bonus dice on the designated surface at the same time;
(d) in response to the pre-point roll:
(i) recognizing a win and making a predetermined payout on each play whereby if the integers showing on upper sides of the first pair of cubic dice totals (11);
(ii) recognizing a tie for each play wager if the integers showing on upper sides of the first pair of cubic dice totals (7); and
(iii) recognizing a loss on and collecting each play wager if the integers showing on upper sides of the first pair of cubic dice total (2), (3) or (12); or
(iv) establishing the number comparison point for subsequent wagering and dice rolls if the integers showing on upper sides of the first pair of cubic dice total (4), (5), (6), (8), (9), or (10), and with the number comparison point corresponding to the integer total and the dealer denoting the established number comparison point with a marker on the corresponding designated area of the designated surface;
(e) repeating steps a-c until a number comparison point is established consistent with step (d)(iv);
(f) after a point is established, placing a late play wager by any new player and placing a bonus wager by any player who placed a play wager at step (a);
(g) use of the dice cup by the shooter to make a post-point roll of the first pair of cubic dice and the second pair of cubic bonus dice on the designated surface at the same time;
(h) in response to the post-point roll:
(i) repeating the post-point roll if the integers showing on upper sides of the first pair of cubic dice do not total the point or (7);
(ii) recognizing and making a predetermined payout on each play wager and each late pay wager if the integers showing on upper sides of the first pair of cubic dice total the point; or
(iii) recognizing a loss on and collecting each play wager if the integers showing on upper sides of the first pair of cubic dice total (7); and
(i) in response to each post-point roll:
(i) recognizing a loss on and collecting each bonus wager if the integers showing on upper sides of the first pair of cubic dice total (7) and the markings on upper sides of the second pair of cubic bonus dice are any combination other than the “Y” on the first die having the “Y” marking and the “O” on the second die having the “O” marking; or
(ii) recognizing and making a predetermined payout on each bonus wager on each dice roll after the point is established if the markings on upper sides of the second pair of cubic bonus dice are the “Y” on the first die having the “Y” marking and the “O” on the second die having the “O” marking.

US Pat. No. 10,427,026

LONGBOARD-SKATEBOARD AND LONGBOARD-SKATEBOARD CONVERSION KIT

1. A structural support member for a conventional snowboard for converting the conventional snowboard to a longboard-skateboard comprising:providing a conventional snowboard having a substantially flat deck; and
said deck having a length to width ratio of 6.15 to 1; and
said deck having a deck long-axis; and
said deck comprising an upper surface and a substantially flat lower surface; and
said deck further comprising a front portion, a rear portion and a middle portion; and
a single substantially linear structural member, comprising:
a length to width ratio of 14 to 1; and
a structural-member long-axis; and
a first end and a second end at each end of said long axis; and
both first and second end being between 0.375 and 0.75 of the thickness of the majority of the substantially linear member; and
said substantially linear member fixedly engaged with said deck substantially flat lower surface with said deck long-axis collinear with said structural-member long-axis; and
providing a first skateboard truck assembly and a second skateboard truck assembly; and
said first truck assembly mounted on said deck substantially flat lower surface, proximal to said deck front portion; and
said second truck assembly mounted on said deck substantially flat lower surface, proximal to said deck rear portion; anda conventional snowboard is converted to a skateboard as said substantially linear member provides sufficient structure to prevent excessive flexion of the deck such that the lower portion of the deck does not contact a surface over which the truck assemblies are in contact with; and wherein said substantially linear member returns to its original shape after being flexed.

US Pat. No. 10,427,024

MECHANICALLY PROPELLED SNOWBOARD

1. A mechanically propelled snowboard comprising:a board;
a frame coupled to the board and extending from an upper face of the board proximate to a tail section of the board;
a pair of bindings coupled to the upper face of the board wherein each binding is configured for coupling to a respective foot of a user for coupling the user to the board;
a propulsion assembly coupled to the frame, the propulsion assembly comprising:
an engine,
a pair of wheels, a respective wheel being operationally coupled to the engine, and
an endless track operationally coupled to the pair of wheels such that a lower limit of the endless track is substantially coplanar with a lower face of the board wherein the engine is positioned for selectively rotating the endless track concurrently with the respective wheel for propelling the board and the user along a surface;
a controller operationally coupled to the engine wherein the controller is positioned for selectively throttling, braking, and shifting the engine; and
the frame comprising
a pair of first plates coupled to the board and extending from the upper face of the board proximate to the tail section of the board;
a slot positioned in the tail section;
a pair of bars, each bar being coupled to and extending from a respective first plate through the slot such that the bar is substantially parallel to the lower face of the board; and
an engine mount coupled to and extending between the bars.

US Pat. No. 10,427,020

BASKETBALL SHOT TRAINING DEVICE

1. A training device for training a player to shoot a basketball, the device comprising:a plate member configured to engage at least a portion of a hand and wrist of a non-shooting hand of the player;
at least one attachment member connected to the plate member and configured to secure the plate member to the non-shooting hand of the player;
a link strap connected at a first end to the plate member and having an aperture through which a wrist of a shooting hand of the player can be aligned;
wherein the plate member includes a main portion and a thumb portion extending from the main portion, and wherein the at least one attachment member includes a thumb strap configured to secure a thumb of the non-shooting hand to the plate member such that movement of the thumb relative to the plate member is restricted;
whereby the non-shooting hand and the shooting hand are linked together such that the non-shooting hand is restricted from rotation relative to the shooting hand when the non-shooting hand and the shooting hand are placed in spaced relation on an associated basketball.

US Pat. No. 10,427,016

GOLF CLUB TRACKING SYSTEM

1. A golf club tracking system for tracking the removal and replacement of golf clubs relative to a golf bag by a golfer, the golf club tracking system comprising:one or more golf club tags associated with one or more of the golf clubs such that the one or more golf club tags are located on the golf clubs and including a golf club tag housing and a golf club transmitter located within the golf club tag housing;
a golfer tag associated with the golfer such that the golfer tag is located on the golfer and including a golfer tag housing and a golfer transmitter located within the golfer tag housing;
a base detector associated with the golf bag including a processor in electronic communication with an antenna for detecting a signal of at least one of the golf club transmitters and the golfer transmitter to determine proximity of the one or more golf club tags and the golfer tag with the base detector;
wherein when the golfer tag is determined to be within proximity of the base detector based a signal of the golfer transmitter detected on the base detector, the one or more golf club tags are inventoried by determining a number of golf club tags in proximity to the base detector based on signals from the golf club transmitters of the one or more golf club tags being detected on the antenna of the base detector to indicate that the one or more golf clubs are therefore within the golf bag; and
wherein when fewer than all of the one or more golf club tags are detected by the base detector when the golfer tag is determined to be within proximity to the base detector, one of the base detector and golfer tag generates an alert.

US Pat. No. 10,427,014

GOLF CLUB

Taylor Made Golf Company,...

1. A golf club head for an iron-type club, the golf club head comprising:a cavity-back iron-type body including a heel portion, a sole portion, a toe portion, a top-line portion, and a face portion, wherein the sole portion extends rearwardly from a lower end of the face portion and the body defines an open cavity behind the face portion;
wherein the face portion includes an ideal striking location that defines the origin of a coordinate system in which an x-axis is tangential to the face portion at the ideal striking location and is parallel to a ground plane when the body is in a normal address position, a y-axis extends perpendicular to the x-axis and is also parallel to the ground plane, and a z-axis extends perpendicular to the ground plane, wherein a positive x-axis extends toward the heel portion from the origin, a positive y-axis extends rearwardly from the origin, and a positive z-axis extends upwardly from the origin;
wherein the club head includes a central region in which ?25 mm wherein at least one face channel is defined in the face portion in a location outside of the central region and proximate to at least one of the toe portion, heel portion and top line portion, the at least one channel being defined through an entire thickness of the face portion;
wherein at least one sole channel is defined in the sole portion, the at least one sole channel being defined through an entire thickness of the sole portion into the open cavity of the golf club head;
wherein a damper is included in the open cavity of the golf club head, wherein the damper does not extend over the at least one face channel; and
wherein at least one point on the face having an x-axis coordinate of ?30 mm has a contact time that is at most 130 microseconds less than a contact time at the ideal striking location.

US Pat. No. 10,427,013

GOLF CLUB HEAD OR OTHER BALL STRIKING DEVICE WITH FACE HAVING MODULUS VARIANCE

Karsten Manufacturing Cor...

1. An iron-type golf club head, comprising:a top portion;
a sole portion opposite the top portion;
a heel portion;
a toe portion opposite the heel portion;
a front portion including a ball striking surface and an inner surface opposite the ball striking surface;
an insert that is integral to the front portion;
a rear cavity opposite the front portion;
wherein the insert comprises a plurality of layers that extends from a portion of the ball striking surface to a portion of the inner surface, such that each layer thereof comprises a different modulus,
wherein the plurality of layers include a first layer, a second layer, a third layer, and a fourth layer, and
wherein the first layer has the highest modulus followed by the second layer, the third layer, and the fourth layer.

US Pat. No. 10,427,012

GOLF CLUB HEADS WITH RIBS AND RELATED METHODS

Karsten Manufacturing Cor...

1. A golf club head comprising:a body comprising:
a heel end, a toe end, a crown, a sole, a front wall comprising a strikeface, and a rear side;
an interior surface defined by the heel end, the toe end, the crown, the sole, the front wall, and the rear side; and
an interior cavity bounded by the interior surface;
and
ribs protruded from a rib surface of the body;
wherein:
the ribs comprise:
a first rib comprising:
a first first-rib endpoint;
a second first-rib endpoint; and
a first rib axis intersecting the first and second first-rib endpoints;
a first rib length, a first rib width, and a first rib height; wherein:
 the first rib length extends from the first first-rib endpoint to the second first-rib endpoint;
 the first rib width is substantially parallel to the rib surface and substantially orthogonal to the first rib length; and
 the first rib height is substantially orthogonal to the rib surface; and
a second rib comprising:
a first second-rib endpoint;
a second second-rib endpoint; and
a second rib axis intersecting the first and second second-rib endpoints;
a second rib length, a second rib width, and a second rib height; wherein:
 the second rib length extends from the first second-rib endpoint to the second second-rib endpoint;
 the second rib width is substantially parallel to the rib surface and substantially orthogonal to the second rib length; and
the second rib height is substantially orthogonal to the rib surface; and
a third rib comprising:
a first third-rib endpoint;
a second third-rib endpoint; and
a third rib axis intersecting the first and second third-rib endpoints;
 the third rib length extends from the first third-rib endpoint to the second third-rib endpoint;
 the third rib width is substantially parallel to the rib surface and substantially orthogonal to the third rib length; and
 the third rib height is substantially orthogonal to the rib surface; and
with respect to a top view of the golf club head:
the first, second, and third rib axes intersect each other and are tangent to a locus defined by a conic section perimeter; and
one or more of the first rib width, the second rib width, and the third rib width vary respectively across the first rib length, the second rib length, and the third rib length;
the first rib axis is tangent to the conic section perimeter at a first tangency point located towards a heelside end of the conic section perimeter;
the second rib axis is tangent to the conic section perimeter at a second tangency point located towards a toeside end of the conic section perimeter; and
the third rib axis is tangent to the conic section perimeter at one of:
a third tangency point located between the first tangency point and a most rearward point of the conic section perimeter; or
a fourth tangency point located between the second tangency point and the most rearward point of the conic section perimeter.

US Pat. No. 10,427,010

HIGH DENSITY OUTER LAYER OF A GOLF CLUB HEAD

Karsten Manufacturing Cor...

1. A golf club head comprising:a body comprising a body material having a body material density, the body including:
a crown,
a sole opposite the crown,
a heel,
a toe opposite the heel, and
a back end;
a strike face made of a strike face material having a strike face material density;
an outer surface;
an inner surface;
a weight pad or a weight member; and
a coating positioned directly on and in contact with the outer surface of a portion of the sole near the back end of the club head,
the coating consisting of a coating material having a coating material density, wherein:
the coating material density is greater than the body material density;
the coating material density is between 150 and 400 g/in3;
the coating comprises a thickness greater than 0.00001 inch and less than 0.001 inch; and
the body material comprises titanium;
wherein the coating covers over the weight pad or the weight member of the golf club head;
wherein a shape of the coating consists of a shape of the weight pad or weight member.

US Pat. No. 10,427,009

US Pat. No. 10,427,008

MULTI-LAYER CORE GOLF BALL INCORPORATING INTERMEDIATE COMPOSITE LAYER COMPRISED OF FUNCTIONALIZED NANOSTRUCTURES

Acushnet Company, Fairha...

1. A golf ball comprising:an inner core comprising a center formed from a first thermoset composition, wherein the inner core has a diameter of from 0.5000 inches to 1.580 inches, a center hardness of from 40 Shore C to 70 Shore C, and a surface hardness of from 50 Shore C to 95 Shore C;
an intermediate core layer having a thickness of from 0.0010 inches to 0.070 inches and an outer surface hardness of from 65 Shore D to 95 Shore D and formed from a composite composition comprising functionalized nano-structures selected from the group consisting of functionalized graphene, functionalized carbon nanotube, functionalized polyamide nano-fiber, and combinations thereof;
an outer core layer formed from a second thermoset composition and having a thickness of from 0.010 inches to 0.075 inches and an outer surface hardness of from 45 Shore C to 90 Shore C; and
a cover layer having a thickness of from 0.010 inches to 0.050 inches and formed from a composition having a material hardness of from 30 Shore D to 65 Shore D.

US Pat. No. 10,426,999

EXERCISE EQUIPMENT FOR THE PERFORMANCE OF HAMSTRING ECCENTRIC AND CONCENTRIC EXERCISES

1. An exercise apparatus for a performance of hamstring eccentric and/or concentric exercises, the exercise apparatus comprising:i. a collapsible frame comprising: a main support bar running centrally to a length of the exercise apparatus; an extended horizontal bar substantially perpendicular to the main support bar attached at a center thereof to a lower end of the main support bar; and
an extended vertical bar, substantially perpendicular both to the main support bar and to the extended horizontal bar, attached at a location along a length thereof to an upper end of the main support bar, so as to fix the main support bar in position, the extended vertical bar having a horizontal bar attached perpendicularly to a lower end thereof, such that, in combination with the extended horizontal bar at the lower end of the main support bar, a stable platform for the exercise apparatus is formed;
ii. a kneeling pad fixed to an upper surface of the main support bar, the kneeling pad configured to be of sufficient length to accommodate lower legs of a user from the user's knees to the user's ankles; and
iii. a foot anchor attached to an upper end of the extended vertical bar, proximal to an upper end of the kneeling pad, the foot anchor mounted above the kneeling pad and configured to maintain the lower legs of the user, from the user's knees to the user's ankles, against an upper face of the kneeling pad when the user performs the hamstring eccentric and/or concentric exercises, the foot anchor being linked to the collapsible frame in such a manner as to allow it to be height adjusted with respect to the kneeling pad;
wherein the main support bar is fixable in an inclined position with respect to a surface on which the exercise apparatus rests; and
wherein, when the exercise apparatus rests on the stable platform, the upper face of the kneeling pad is inclined between 5 degrees and 20 degrees with respect to a horizontal orientation relative to the surface, the extended vertical bar is adjacent to the kneeling pad, and the upper end of the extended vertical bar is spaced a vertical distance above the upper face of the kneeling pad.

US Pat. No. 10,426,996

REHABILITATION MACHINE AND APPARATUS

1. An exercise apparatus, comprising:a main support column;
a first arm with a proximal end and a distal end, hingedly connected at a first height to the main support column at the proximal end;
a second arm with a proximal end and a distal end, hingedly connected at a second height to the main support column at the proximal end, wherein the second height is greater than the first height;
a first rotary mechanism located at the distal end of the first arm, said first rotary mechanism adapted to move a set of pedals in a rotary fashion; and
a second rotary mechanism located at the distal end of the second arm, said second rotary mechanism adapted to move a set of handles in a rotary fashion.

US Pat. No. 10,426,995

ARM EXERCISE ASSEMBLIES

1. An arm exercise assembly, comprising:a frame shaped and sized to receive a human forearm;
a piston coupled to the frame;
a bracket pivotably coupled to the frame;
a wheel coupled to the piston and pivotably coupled to the bracket;
two locks extending radially through the wheel toward inner portions of the wheel; and
a handle pivotably coupled to the wheel, wherein the handle is capable of being abutted against one or both of the two locks.

US Pat. No. 10,426,992

BARBELL MASSAGE APPARATUS

1. In combination with a barbell having a cylindrical surface, wherein an improvement comprises:a barbell massage apparatus including:
a spherical member defining an exterior massage-contact surface;
at least two arms extending away from the exterior massage-contact surface that respectively flank two sides of the cylindrical surface of the barbell and retain the barbell massage apparatus thereon, the at least two arms at least partially defining a U-shaped channel with the cylindrical surface of the barbell disposed therein; and
a spherical member sleeve sized and shaped to removably cover at least a portion of the exterior massage-contact surface, the spherical member sleeve defining a second exterior massage-contact surface;
wherein the spherical member defines at least one groove; and the spherical member sleeve includes at least one lip dimensioned to matingly fasten to the at least one groove so as to secure the spherical member sleeve on the spherical member, the second exterior massage-contact surface includes a plurality of massage projections that extends outwardly and away from the spherical member when the spherical member sleeve is secured to the spherical member through the at least one lip and the at least one groove.

US Pat. No. 10,426,991

EXERCISE DEVICE

1. An exercise device, comprising:a straight track comprising a first end and a second end;
a track carriage disposed on and movable in a first plane along said track, said track carriage including a handle on each of two sides of said track carriage extending widthwise with respect to said track;
a resistance system selectively engageable with said track carriage to provide variable resistance or assistance to movement of said track carriage along said track;
a platform having a support surface adapted to support a user of the device in seated and kneeling positions, wherein said platform is rotatably secured to said track carriage such that said platform rotates left and right relative to said track carriage, in a second plane substantially parallel to the first plane, about an axis that is perpendicular to said track;
a bracket coupled to the second end of said track; and
a vertical support including a plurality of support positions each adapted to support said bracket for selectively varying a height of the bracket and the second end of said track relative to the first end of said track.

US Pat. No. 10,426,990

CONVERTIBLE BENCH AND UPRIGHT STABILIZING SUPPORT

HOIST FITNESS SYSTEMS, IN...

1. An exercise machine, comprising:a frame;
an arm exercise assembly that is vertically positionable on the frame; and
a workout station connected to the frame, the workout station comprising:
a seat,
a stabilizing support,
an extendable post connected to the stabilizing support, and
a pivot adjustment mechanism connected to the extendable post,
wherein the pivot adjustment mechanism pivots the extendable post forwards and backwards such that the position of the stabilizing support is configured to be adjusted forwards and backwards, and
wherein the extendable post is configured to be extended or retracted to adjust the height of the stabilizing support,
and wherein the seat is connected to the extendable post such that the seat and the extendable post pivot together as a unit when the pivot adjustment mechanism is adjusted.

US Pat. No. 10,426,989

CABLE SYSTEM INCORPORATED INTO A TREADMILL

1. A treadmill, comprising;an opening formed in a surface running side of a running deck;
a resistance mechanism including a flywheel incorporated into the running deck;
a sensor connected to the resistance mechanism, the sensor configured to determine one or more of a number of revolutions and a number of partial revolutions of the flywheel;
a cable threaded through the opening where the cable comprises a resistance end connected to the resistance mechanism and a pull end accessible through the running deck;
a display connected to the treadmill; and
a processor in communication with the display and configured to perform:
measuring aerobic calories burned during aerobic exercise using the running deck;
measuring pulling anaerobic calories burned during pulling anaerobic exercise using the resistance mechanism and using the sensor to provide information to the processor about energy expended during pulling anaerobic exercise using the resistance mechanism using one or more of the number of revolutions and the number of partial revolutions of the flywheel; and
displaying the aerobic calories burned and the anaerobic calories burned.

US Pat. No. 10,426,988

RESISTANCE EXERCISE DEVICE

1. A resistance exercise device that is held in at least one hand of a user and whirled in use, comprising:an elongated handle having a first handle end and a second handle end;
an elongated element having a first end, a second end, and defining a longitudinal axis extending through the first end and the second end, at least a portion of the elongated element proximate the first end being flexible;
a coupling connecting the elongated element at or near the first end to the elongated handle at or near the first handle end; and
a plurality of resistance fins attached to the elongated element, the resistance fins disposed around and along a portion of the elongated element and oriented in an outwardly direction from the longitudinal axis, the elongated element and attached resistance fins being at least generally symmetrical along the longitudinal axis,
whereby when whirled in use, the elongated element and the attached resistance fins prevent rotation about the longitudinal axis and produce a substantially continuous resistance exercise.

US Pat. No. 10,426,987

FIREFIGHTING FOAM GENERATOR

1. A firefighting foam generator including:a receptacle for receiving a flow of liquid;
a gas supply for supplying pressurized gas into the flow of liquid to create foam, the gas supply comprising a tube which extends into the receptacle transverse to the flow of liquid, the tube includes a plurality of gas outlets, and
a first and second turbulence creator, each for creating turbulence in the receptacle,
the first turbulence creator including a baffle positioned within the receptacle at a first location spaced apart from and upstream of the tube, relative to the flow of liquid, and
the second turbulence creator including a baffle positioned within the receptacle at a second location downstream of the tube, relative to the flow of liquid,
each turbulence creator comprising an edge, positioned transverse to the flow of liquid which extends between and contacts the receptacle at a first position and a second position.

US Pat. No. 10,426,986

BRACKET FOR INSTALLATION OF A FIRE PROTECTION SPRINKLER

The Reliable Automatic Sp...

1. A support bracket for use in installing a sprinkler fitting for a fire protection sprinkler in a building having a ceiling that includes a structure, the support bracket comprising:(A) a support beam configured to extend over a space within the structure of the ceiling;
(B) at least one end bracket provided at a first end of the support beam, and configured to attach the support bracket to the structure of the ceiling, the at least one end bracket comprising:
(a) an upper body;
(b) a lower grip including:
(i) a first leg;
(ii) a second leg that is adjacent to the first leg; and
(iii) a third leg that is adjacent to the second leg, the second leg being provided between the first leg and the third leg, wherein a width of the second leg is roughly equal to or greater than a combined width of the first leg and the third leg; and
(c) a connecting portion that joins the upper body and the lower grip; and
(C) a center bracket supported by the support beam, and configured to receive at least a portion of the sprinkler fitting, the center bracket including:
(a) a body that defines an opening to receive the portion of the sprinkler fitting;
(b) a closure assembly including:
(i) a first pin mounted in the body and having a first pin axis;
(ii) a closure member having a first end rotatably connected to the body by the first pin, and a second end that includes a handle, the closure member being rotatable about the first pin axis relative to the body, and being movable between an open position and a closed position, wherein, when the closure member is in the closed position and the portion of the sprinkler fitting is received in the opening of the body, the closure assembly presses the portion of the sprinkler fitting against at least one of the body and the support beam and urges the center bracket against the support beam to maintain the center bracket stationary relative to the support beam;
(iii) a second pin mounted in the body at a distance from the first pin, the second pin having a second pin axis; and
(iv) a lever rotatably connected to the body by the second pin, and positioned relative to the closure member such that, when the closure member moves from the open position to the closed position, the closure member contacts and rotates the lever to cause the lever to press the portion of the sprinkler fitting against the at least one of the body and the support beam; and
(c) a lock inserted into the body, spaced from the first pin and the second pin, and configured to engage the closure member when the closure member moves in a direction from the open position toward the closed position, and to engage the closure member to prevent the closure member from returning from the closed position to the open position.

US Pat. No. 10,426,984

SPRINKLER ASSEMBLY

The Viking Corporation, ...

1. A sprinkler assembly comprising:a body including a passageway, an inlet opening, a discharge opening, and a central axis extending through said discharge opening;
a support extending from said body at a first fixed location downstream relative to the discharge opening of the body;
a closure device releasably positioned at said discharge opening to close said passageway;
a heat responsive trigger mounted to releasably retain said closure device at said discharge opening of said body; and
a flow shaper non-movably secured to said support at a second fixed location downstream relative to the discharge opening of the body, said flow shaper including a transverse wall portion intersecting said central axis, said transverse wall portion being rectangular with a pair of longer side edges and a pair of relatively shorter end edges a pair of laterally spaced sidewalls integrally formed with and extending from said longer side edges of said transverse wall portion toward said body and a pair of mounting base portions integrally formed with and extending from said pair of sidewalls and connected to the support for supporting the flow shaper to said support.

US Pat. No. 10,426,983

FIRE SPRINKLER SYSTEM HAVING COMBINED DETECTION AND DISTRIBUTION PIPING

1. A fire sprinkler system in communication with a source of fire extinguishing fluid, the fire sprinkler system comprising:a piping system having at least one dual-use pipe providing both an air opening and a fire extinguishing fluid conveying outlet, the at least one dual-use pipe having at least one air conveying opening;
a blower fluidly connected to the at least one dual-use pipe to provide a substantially continuous flow of ambient air through the at least one dual-use pipe, the ambient air entering or exiting the at least one dual-use pipe via the at least one air conveying opening;
a control unit fluidly connected to the at least one dual-use pipe to measure the flow of the ambient air therethrough, the control unit operable to detect a difference between a measured airflow rate value of the ambient air through the at least one dual-use pipe and a baseline airflow rate value of the ambient air, a fire condition being detected by the control unit when a difference between the baseline airflow rate and the measured airflow rate exceeds a predetermined delta value;
a selective flow valve mounted in sealed engagement about the air opening, the ambient air flowing freely through the selective flow valve into or out of the at least one dual-use pipe upon the difference between the baseline and measured airflow rate values not exceeding the predetermined delta value;
a valve disposed between the source of the fire extinguishing fluid and the at least one dual-use pipe, the valve being in communication with the control unit and operable to displace between an open position to fill the at least one dual-use pipe with the fire extinguishing fluid upon detection of the fire condition, and a closed position; and
at least one automatic sprinkler fluidly connected to the at least one dual-use pipe for ejecting the fire extinguishing fluid from the at least one dual-use pipe upon detection of the fire condition, said at least one automatic sprinkler having a frangible component, the frangible component breaking to create a supplemental airflow path through the at least one automatic sprinkler between the at least one dual-use pipe and surrounding ambient air, the supplemental airflow path increasing the difference between the baseline and measured flow rate values beyond the predetermined delta value, and to eject the fire extinguishing fluid from said at least one automatic sprinkler upon an increase in temperature of the ambient air being indicative of the fire condition.

US Pat. No. 10,426,982

LINE SECURING DEVICE

1. A securing device for securing a person, the securing device comprising:a support structure;
a rope drum, on which a safety rope, to which the person is attachable, is reelable;
an axle element, which is attached in a non-rotational manner to the rope drum and rotatably to the support structure, such that, by the axle element, the rope drum is supported rotatably to the support structure;
a lever
attached pivotably to the support structure at a deflection point,
wherein the lever has a blocking section, which is configured
such that, in a blocking position of the lever, the blocking section is coupled to the rope drum in order to disable a rotation of the rope drum, and
such that, in a releasing position of the lever, the blocking section is decoupled from the rope drum and the rope drum is rotatable,
wherein the lever has a first thread section, which is spaced apart from the blocking section;
wherein the axle element has a second thread section,
wherein the first thread section is coupled to the second thread section, such that, upon rotation of the axle element, due to the rotation of the rope drum, the first thread section is shifted along the axle element, such that, due to the shifting of the first thread section, a rotation of the lever around the deflection point and an adjustment between the blocking position and the releasing position of the lever are effected.

US Pat. No. 10,426,978

ULTRASONIC TREATMENT APPARATUS

OLYMPUS CORPORATION, Tok...

1. An ultrasonic treatment apparatus comprising:a high frequency supply section configured to supply a high frequency electric power;
a probe main body extending from a proximal direction toward a distal direction along a longitudinal axis, the probe main body receiving the high frequency electric power supplied from the high frequency supply section, the probe main body being configured to transmit an ultrasonic vibration from the proximal direction toward the distal direction such that a longitudinal vibration is generated in a vibrating direction parallel to the longitudinal axis;
a distal treatment section positioned on a distal direction side with respect to a most distal node position positioned most distally among node positions of the longitudinal vibration in the probe main body, the distal treatment section being configured to apply the ultrasonic vibration transmitted through the probe main body to a treated object, and the high frequency electric power being supplied to the distal treatment section through the probe main body such that the distal treatment section is a first electrode;
a jaw that is openable and closable relative to the distal treatment section, the high frequency electric power being supplied to the jaw from the high frequency supply section such that the jaw is a second electrode different in potential from the first electrode in a position facing the first electrode, a high frequency current flowing between the second electrode and the first electrode when the distal treatment section is the first electrode and the jaw is the second electrode;
a sheath through which the probe main body is inserted in a state where the distal treatment section is projected toward the distal direction, the sheath forming an electric path of the high frequency electric power that is supplied to the jaw, the sheath being spaced from the probe main body;
a probe side facing surface provided in a position facing the jaw in a surface of the distal treatment section, the probe side facing surface being configured to grip the treated object between the probe side facing surface and the jaw, frictional heat being generated on the probe side facing surface by the longitudinal vibration of the probe main body due to the ultrasonic vibration, and the high frequency current, which flows between the first electrode and the second electrode, passing through the probe side facing surface; and
a coating portion made of a material having electrically insulating properties and having a higher heat resistance than the probe main body, the coating portion coating the surface of the distal treatment section except for the probe side facing surface, the high frequency current that flows between the first electrode and the second electrode being prevented from passing through the coating portion due to the electrically insulating properties of the coating portion such that a current density of the high frequency current, which passes through the probe side facing surface, is increased, wherein:
a first part that is coated with the coating portion in the surface of the distal treatment section includes a proximal-region surface located on a proximal direction side with respect to the probe side facing surface,
the coating portion directly adheres to the surface of the distal treatment section in the proximal-region surface, and
the proximal-region surface includes a completely-coated region, the completely-coated region being provided at least in a second part that is located inside the sheath, the coating portion coating an entire-periphery of the surface of the distal treatment section around the longitudinal axis in the completely-coated region, wherein the jaw includes a jaw inclined surface which faces the probe side facing surface and which is inclined relative to an opening and closing direction of the jaw, and a third part of the probe side facing surface which faces the jaw inclined surface is not covered with the coating portion.

US Pat. No. 10,426,976

NITINOL ORGAN POSITIONER TO PREVENT DAMAGE TO HEALTHY TISSUE DURING RADIATION ONCOLOGY TREATMENTS

The University of Toledo,...

1. An organ repositioner device comprising:an inflatable balloon mounted on a bendable tube defining a lumen, the lumen housing an assembly of a shape memory (SM) element and a superelastic (SE) element, wherein the SM element comprises a first shape memory alloy and has a first shape set form, and the SE element comprises a second shape memory alloy and has a second shape set form;
wherein the bendable lumen bends upon shape transformations of the assembly, and the assembly has an equilibrium shape between the first shape set form and the second shape set form.

US Pat. No. 10,426,975

ELASTICITY IMAGING-BASED METHODS FOR IMPROVED GATING EFFICIENCY AN DYNAMIC MARGIN ADJUSTMENT IN RADIATION THERAPY

KONINKLIJKE PHILIPS N.V.,...

1. A therapy plan execution control system comprising:at least one processor programmed to:
receive initial elasticity data indicative of a location of the target generated prior to execution of a fraction of a treatment plan for the target;
receive additional elasticity data indicative of a location of the target generated during execution of the fraction;
compare the initial elasticity data and the additional elasticity data to identify at least one of motion of the target and changes of the target;
during execution of the fraction, identifying real-time changes in the target due to therapy delivery based on the comparison; and
controlling execution of the fraction based on the identified changes in the target;
wherein the comparing of the initial elasticity data to the additional elasticity data comprises using intra-fraction elasticity imaging to identify real-time changes occurring in the target due to therapy delivery, and using inter-fraction elasticity imaging to identify target shrinkage, and further comprising adjusting the margins of the treatment plan and reoptimizing the treatment plan upon a determination that the target has changed in size.

US Pat. No. 10,426,973

VIVO DRUG DEVELOPMENT AND DELIVERY SYSTEMS AND METHODS

1. A method of producing and administering a therapeutic drug to a patient, said method comprising:piercing the skin of the patient and positioning an ionizable substrate drug delivery apparatus at a treatment area inside a tissue of the patient;
directing an ionizable substrate solution into a chamber of the ionizable substrate drug delivery apparatus;
exposing the ionizable substrate solution to ionizing radiation in the chamber, thereby converting the ionizable substrate solution to free radicals; and
injecting the free radicals into said tissue of the patient
wherein:
the ionizable substrate delivery apparatus comprises:
an outer cannula configured for piercing the skin of the patient;
a body defining an inner chamber for receiving an ionizable substrate solution;
a structure within the inner chamber for transmitting ionizing radiation to the ionizable substrate solution in the chamber thereby developing a free radical drug; and
an applicator for directing the free radical drug from the chamber to a treatment site.

US Pat. No. 10,426,971

PHOTOTHERAPY DEVICE WITH PAIN LOCATION INPUT

KONINKLIJKE PHILIPS N.V.,...

1. A phototherapy device for relieving nociceptive pain of a body part of a user by illumination of at least a part of the body part, comprising:a patch structure arranged to conform to at least a part of the body part;
a controllable light source system comprising at least one light source arranged on the patch structure so as to allow phototherapeutic illumination of at least a part of the user's body part, when the patch structure is positioned on the body part;
a user interface having a touch sensitive panel arranged on the opposite side to the side conforming to the at least a part of the body part, wherein the touch sensitive panel is arranged to sense a force applied by an input of the user corresponding to the noicipceptive pain such that the input from the user corresponds to a spatial position on the body; and
a control system arranged to control the controllable light source system in accordance with the input from the user such that the phototherapeutic illumination is correlated to the force applied by the input of the user.

US Pat. No. 10,426,970

IMPLANTABLE OPTICAL STIMULATORS

The Board of Trustees of ...

1. A device for stimulating target cells having light-responsive proteins in an animal, the device comprising:an elongated light-delivery structure configured for insertion in a narrow passageway in the animal, the elongated light-delivery structure having a distal end, a proximal end, an array conformed to an outer surface around a circumference of the distal end, and a plurality of separately-activatable light-delivery elements, wherein each light-delivery element extends from the proximal end to the array and separately terminates at an aperture at a specific array location;
a control circuit for activating less than all the light-delivery elements that are electrically connected in parallel to deliver light to light-responsive proteins adjacent to the activated light-delivery elements along the length of the elongated light-delivery structure, thereby stimulating target cells in vivo, wherein groups of separately-activatable light-delivery elements are affixed to each other to form a ring;
a multichannel driver configured to individually control the light-delivery elements;
a sensor for detecting a measure of performance of the animal; and
a computer configured for storing the measure of performance of the animal and using the measure of performance of the animal to determine a neuromodulation parameter for the multichannel driver, wherein the neuromodulation parameter is a direction of the light emitted from the array of light-delivery elements,
wherein the device is configured to:
generate sets of candidate neuromodulation parameters, wherein the sets of candidate neuromodulation parameters comprise control information for the plurality of light-delivery elements;
activate the plurality of light-delivery elements according to one or more of the sets of candidate neuromodulation parameters;
detect neuromodulation effects from the activation of the plurality of light-delivery elements;
correlate the one or more sets of candidate neuromodulation parameters with the detected neuromodulation effects; and
select one of the sets of candidate neuromodulation parameters as a treatment regimen for the animal.

US Pat. No. 10,426,968

NEURAL MODULATION SYSTEM

Palo Alto Research Center...

1. A vision prosthetic system, comprising:a camera configured to provide camera signals in response to images;
a patient-external device comprising:
a neural encoder programmed to convert the camera signals into a neural stimulation pattern; and
communication circuitry configured to wirelessly transmit the stimulation pattern to a patient-internal device configured to be disposed within a cranium of a patient;
the patient-internal device comprising:
communication circuitry configured to wirelessly receive the stimulation pattern from the patient-external device;
an implantable neural subsystem, comprising:
a flexible substrate;
a two dimensional array of neural probes disposed on the flexible substrate, the neural probes configured to stimulate and sense neurons, each neural probe comprising:
an array of magnetic neural stimulators configured to magnetically stimulate neurons;
an array of neural sensors configured to sense neural signals of the neurons; and
probe addressing circuitry comprising thin film switches; and
control circuitry configured to control activation of the magnetic neural stimulators and neural sensors according to the neural stimulation pattern via the probe addressing circuitry.

US Pat. No. 10,426,965

METHOD AND APPARATUS FOR DETERMINING BATTERY CAPACITY IN A DEFIBRILLATOR

Scion Medical Limited, H...

1. A method for notifying a user to replace a battery in a defibrillator, the method comprising:measuring the battery voltage during operation of the defibrillator;
counting the number of shocks delivered during operation of the defibrillator; and
notifying the user that the battery in the defibrillator needs to be replaced when:
(i) the number of shocks delivered during operation of the defibrillator is >19; or
(ii) the number of shocks delivered during operation of the defibrillator is >6 and the battery voltage measured during operation of the defibrillator is <9.03 volts; or
(iii) the number of shocks delivered during operation of the defibrillator is between 6 and 4, and the battery voltage measured during operation of the defibrillator is <7.87 volts; or
(iv) the number of shocks delivered is between 3 and 1, and the battery voltage measured during operation of the defibrillator is <7.39.

US Pat. No. 10,426,963

ESTIMATING SHOCK SUCCESS BY MONITORING CHANGES IN SPECTRAL DATA

ZOLL Medical Corporation,...

1. A system comprising:one or more electronic ports for receiving signals from sensors for obtaining a time domain electrocardiogram (ECG) of a patient;
a patient treatment module comprising an ECG analyzer and a non-transitory computer-readable storage medium encoded with a computer program comprising instructions that, when executed, cause one or more processors to perform operations comprising:
performing at least one transformation of at least a portion of a time domain ECG signal from the patient into frequency domain data,
determining a first frequency-based value over a first evaluation period based on the at least one transformation,
determining a second frequency-based value representing an upward trend over a second evaluation period based on the at least one transformation, and
determining a probability of therapeutic success based at least in part on the first frequency-based value and the second frequency-based value; and
an output device for presenting an indication of the probability of therapeutic success.

US Pat. No. 10,426,962

LEADLESS PACEMAKER USING PRESSURE MEASUREMENTS FOR PACING CAPTURE VERIFICATION

CARDIAC PACEMAKERS, INC.,...

1. An implantable medical device in the form of a cardiac pacemaker, comprising:at least first and second electrodes for at least one of delivering therapy or sensing electrical signals;
a pressure sensor for sensing intracardiac pressure;
operational circuitry coupled to the electrodes and the pressure sensor; and
a housing sized and adapted for placement in or on the heart of a patient, the housing containing at least the operational circuitry;
wherein the operational circuitry is configured to perform a pressure based capture verification process including the following:
deliver an electrical pacing stimulus to the heart of a patient using the at least first and second electrodes;
obtaining a pressure signal received with the pressure sensor over a period of time following delivery of the electrical pacing stimulus;
monitor for an evoked capture response indicating the electrical pacing stimulus was captured using the pressure sensor by identifying a peak in the pressure signal and determining a temporal relationship of the peak in the pressure signal to a second signal event; and
if the evoked capture response is detected, conclude that the electrical pacing stimulus captured at least a portion of the patient's heart; and
if the evoked capture response is not detected, conclude that the electrical pacing stimulus did not capture the patient's heart.

US Pat. No. 10,426,959

SYSTEMS AND METHODS TO PLACE ONE OR MORE LEADS IN TISSUE FOR PROVIDING FUNCTIONAL AND/OR THERAPEUTIC STIMULATION

SPR THERAPEUTICS, INC., ...

1. A method to reduce and/or relieve pain in a painful region comprising:percutaneously inserting a coiled lead through skin of a patient;
positioning an electrode extending from the coiled lead into adipose or connective tissue outside of the painful region;
stimulating a peripheral nerve innervating the painful region with the electrode, wherein the electrode is positioned near the peripheral nerve; and
evoking a tingling sensation over at least a portion of the painful region without damaging the peripheral nerve.

US Pat. No. 10,426,957

STIMULATION MANAGEMENT

Cochlear Limited, Macqua...

1. A method, comprising:i. obtaining nullity weighting information based on artefact voltages at a first location in a recipient for at least one current level of a plurality of respective first current levels respectively applied to respective electrodes of a sensory prosthesis configured to stimulate tissue of the recipient to evoke a sensory percept;
ii. simultaneously stimulating the respective electrodes at respective second current levels such that a neural response is found at the first location, at least one of the second current levels being weighted by the nullity weighting information; and
iii. automatically recording the neural response resulting from action “ii.”

US Pat. No. 10,426,956

SYSTEM AND METHOD FOR MONITORING AND CONTROLLING NERVOUS SYSTEM BEHAVIOR USING AUTONOMIC FEATURES

University of Florida Res...

1. A system for stimulating the central nervous system via a peripheral nerve input into the autonomic nervous system of a human patient in accordance with the state of the parasympathetic branch of the autonomic nervous system, comprising:monitoring means for continuously monitoring an index of parasympathetic nervous system behavior of the patient;
stimulating means for stimulating the autonomic nervous system, wherein the stimulating means stimulates the vagus nerve or trigeminal nerve so that the central nervous system is affected; and
controlling means operatively connected to the monitoring means and to the stimulating means, the controlling means continuously regulating the stimulating means in a manner that said autonomic nervous system is stimulated in accordance with the monitored index of parasympathetic nervous system behavior of the patient,
wherein the monitored index comprises respiratory sinus arrhythmia, and, optionally, further comprises hippus variability, skin conductance, blood pressure, blood pressure variability or heart rate, and
wherein the controlling means regulates the stimulating means to provide minimal stimulation intensity to increase the monitored index via effects on the central nervous system while not causing patient discomfort.

US Pat. No. 10,426,955

METHODS FOR IMPLANTING ELECTRODES AND TREATING A PATIENT WITH GASTREOSOPHAGEAL REFLUX DISEASE

EndoStim, Inc., Dallas, ...

5. A method of implanting a first electrode and a second electrode in a patient in order to treat gastroesophageal reflux disease, comprising:implanting the first electrode in a stomach of the patient;
implanting the second electrode in a stomach of the patient, wherein the second electrode is positioned skew relative to the first electrode,
connecting the first electrode and the second electrode to a pulse stimulator configured to supply a stimulation pulse to the first electrode and the second electrode;
programming the pulse stimulator to apply a train of stimulation pulses, wherein the pulse stimulator is not in data communication with an implanted sensor configured to sense a physiological state of the patient; and
operating the first electrode and the second electrode in combination to deliver the stimulation pulses to normalize a function of a lower esophageal sphincter (LES) of the patient post-stimulation.

US Pat. No. 10,426,954

LEAD ELECTRODE FOR USE IN AN MRI-SAFE IMPLANTABLE MEDICAL DEVICE

MEDTRONIC, INC., Minneap...

1. A medical lead configured to be implanted into a patient's body, the lead comprising:an elongated lead body having a proximal end and a distal end;
a first conductive filer that is coupled to an electrical contact at the proximal end and that passes through an interior of the lead body to the distal end;
a second conductive filer that is coupled to an electrical contact at the proximal end and that passes through an interior of the lead body to the distal end;
a first electrode that comprises a ring that is coupled to said lead body at the distal end and coupled to the first conductive filer;
a second electrode that comprises a ring that is coupled to said lead body distally of the first electrode at the distal end and coupled to the second conductive filer;
a floating electrode coupled to said lead body and comprising a ring portion and an extension from the ring portion that is capacitively coupled to the first electrode and to the second electrode, wherein the extension of the floating electrode is positioned within the rings of the first and second electrodes.

US Pat. No. 10,426,952

DELIVERY OF CARDIAC STIMULATION DEVICES

BOSTON SCIENTIFIC SCIMED,...

1. A method of implanting a wireless electrode assembly into a heart, comprising:advancing a device through a cardiovascular system of a patient to an implantation site of a wall of a heart;
observing, on an electrocardiogram (ECG), electrical activity of the heart using a sensing electrode on the device and in electrical communication with the ECG;
determining, before penetration of the wall of the heart by a wireless electrode assembly, if the implantation site is suitable for receipt of the wireless electrode assembly based on the observed electrical activity of the heart on the ECG; and
thereafter, deploying the wireless electrode assembly at the implantation site if based on determining, before penetration of the wall of the heart by the wireless electrode assembly, that the implantation site is suitable for receipt of the wireless electrode assembly such that the wireless electrode assembly is fully implanted and anchored into the wall of the heart, the wireless electrode assembly including a body sized to be positioned within a chamber of the heart, the body containing circuitry for delivering electrical stimulation to heart wall tissue from a first electrode of the wireless electrode assembly, through the heart wall tissue, and to a second electrode of the wireless electrode assembly.

US Pat. No. 10,426,949

SYSTEMS AND METHODS FOR OPTIMIZING PROGRAMMING AND USE OF NEUROMODULATION SYSTEMS

Regents of the University...

1. A method for programming a pulse generator with a configuration for a deep brain stimulation array including one or more electrodes, the configuration including a stimulation setting for each electrode in the deep brain stimulation array, the method comprising:identifying one or more grid points representing a target tissue to be activated by stimulation through the one or more electrodes;
identifying one or more objective values to be balanced, the objective values being calculable based on the one or more grid points and a configuration;
generating one or more configurations, such that each configuration is Pareto optimal in terms of the objective values calculated based on the one or more grid points and the configuration;
presenting the one or more configurations to a user;
receiving from the user a selected one of the one or more configurations; and
providing, to a pulse generator capable of delivering therapy via each of the one or more electrodes, the selected configuration.

US Pat. No. 10,426,948

EXTENDABLE ELECTRODE

1. An implantable electrode comprising:at least one contact element for contacting bodily tissue;
a connection portion comprising at least one connecting line for connecting a medical device to the at least one contact element; and
a cylindrical core,
wherein the cylindrical core is flexible along a longitudinal axis of the electrode,
wherein the connection portion is wound around the core and individual turns, or all turns, in the wound form of the cylindrical portion are fastened to the core, and
wherein the connection portion is formed flat and the at least one connecting line is embedded in the flat connection portion,
wherein the at least one connecting line is arranged between two electrically insulating thermoplastic polymer films which are permanently connected to one another,
wherein a first of the two films is planer and has the at least one contact element formed on one of its sides and the at least one connecting line formed on a side of the first film opposite the at least one contact element,
wherein a second of the two films is planar and is connected to the first film on the one side of the first film where the at least one connecting line is formed,
wherein the first and second films forming the connection portion are wound around the core.

US Pat. No. 10,426,947

IMPLANTABLE ELECTRODE WITH HOLLOW CYLINDRICAL SHEATH

1. An implantable electrode comprising:a sheath extending along a longitudinal axis of the electrode, the sheath being made of an electrically insulating material; and
at least one connection cable, wherein the connection cable is at least partly embedded in the sheath and the sheath has a hollow cylindrical shape,
wherein the hollow cylindrical shape of the sheath has an inner side and an outer side,
wherein the electrode has at least one contact element, wherein the at least one contact element has a feedthrough passing through the sheath and forming an electrically conductive connection with the at least one connection cable,
wherein the at least one contact element sits on the outer side of the sheath,
wherein the at least one connection cable is arranged between two electrically insulating thermoplastic polymer films which are permanently connected with one another,
wherein a first of the two films is planar and has the at least one connection cable formed on one of its sides and the at least one contact element formed on a side of the first film opposite the at least one connection cable
wherein a second of the two films is planar and is connected to the first film on the one side of the first film where the at least one connection cable is formed.
wherein the first and second films forming the sheath are wrapped in the form of the hollow cylindrical shape, and
wherein to connect the at least one connection cable and the at least one contact element together the feedthrough is provided with a metalized opening in the one film connecting the two sides of the one film with one another.

US Pat. No. 10,426,946

WEARABLE DEFIBRILLATOR WITH AUDIO INPUT/OUTPUT

ZOLL Medical Corporation,...

1. A wearable defibrillator comprising:a plurality of ECG electrodes configured to be removably attached to a patient and configured to sense a cardiac condition of the patient;
at least one therapy pad configured to deliver electrical therapy to the patient;
at least one audio device, the at least one audio device including
a microphone configured to receive an audio input and sense environmental noise, and
a speaker configured to output one or more alarms signaling that treatment is about to be provided to the patient; and
at least one processor operatively connected to the plurality of ECG electrodes, the at least one therapy pad, a memory, and the at least one audio device, the at least one processor configured to
monitor the sensed cardiac condition, and
increase a volume of the one or more alarms when the microphone senses from the environmental noise that the wearable defibrillator is in a high noise environment.

US Pat. No. 10,426,944

LONG-TERM WEAR ELECTRODE

ZOLL Medical Corporation,...

1. An electrode for use with a therapeutic current delivery system, comprising:a non-conductive, flexible, water vapor-permeable, electrically-insulating top layer; and
a flexible, water vapor-permeable, conductive adhesive material disposed on one side of the electrically-insulating top layer,
wherein the conductive adhesive material is conductive in a direction substantially orthogonal to the plane of the electrode and semi-conductive in a direction substantially lateral to the plane of the electrode; and
wherein the electrode has an overall water vapor permeability greater than 100 gm/m2/24 hours.

US Pat. No. 10,426,938

MEDICAL DRESSING INTERFACE DEVICES, SYSTEMS, AND METHODS

KCI Licensing, Inc., San...

29. A method for instilling fluid at a tissue site, comprising:positioning a distribution manifold adjacent a surface of the tissue site, the distribution manifold comprising a tissue-facing side facing the tissue site and an outward-facing side opposite the tissue-facing side;
positioning an adapter adjacent the distribution manifold, the adapter comprising:
a conduit housing including a recessed region defining an entry surface, the entry surface facing the outward-facing side of the distribution manifold,
a primary port on the entry surface,
at least one ancillary port on the entry surface, and
at least one port extension including a proximal end, a distal end, and a bore between the proximal end and the distal end, the distal end of the port extension in fluid communication with the ancillary port through the bore;
inserting the distal end of the port extension into the distribution manifold; and
delivering fluid to the surface of the tissue site through the ancillary port and the distal end of the port extension.

US Pat. No. 10,426,937

BI-PHASE FLUID SURGE SUPPRESSOR DEVICE

1. A siphon guard comprising:a housing having an inlet and an outlet opposite the inlet, the inlet and outlet being axially alignable with a shunt flow path;
a primary flow path disposed within the housing and in fluid communication with the inlet and the outlet, the primary flow path having a generally axial orientation;
a secondary flow path disposed around the primary flow path and within the housing and in fluid communication with the inlet and the outlet, the secondary flow path having a generally helical orientation and a higher resistance to fluid flow than the primary path; and
a valve disposed within the primary flow path, the valve having a valve seat and a first ball and a second ball, the first ball being movable between a valve closed position where the first ball is moved towards the outlet and in contact with the valve seat and a valve open position where the first ball is moved away from the outlet and spaced from the valve seat thereby permitting egress of fluids from the valve from the first ball and then to the outlet distal thereof,
the first ball is disposed between the second ball and the valve seat,
the second ball being movable between the valve closed position and the valve open position;
wherein the second ball being movable by a weight of the second ball between the valve closed position and the valve open position, and
wherein the primary flow path forms a “u” bend between the inlet and the valve.

US Pat. No. 10,426,936

BALLOON CATHETERS WITH INCREASED COLUMN STRENGTH

BOSTON SCIENTIFIC SCIMED,...

1. A medical device, comprising:an expandable member having a proximal waist and a distal waist;
an outer member having a proximal end, a distal end and a lumen extending therein, wherein the outer member is attached to the proximal waist of the expandable member;
an inner member having a proximal end and a distal end, the inner member disposed within the lumen of the outer member, wherein the inner member is attached to the distal waist of the expandable member; and
a movement limiting member connecting the inner member to the outer member,
wherein the movement limiting member is a coil having a proximal end and a distal end, wherein the distal end of the coil is directly attached to the inner member;
wherein the movement limiting member is configured to limit movement of the outer member relative to the inner member.

US Pat. No. 10,426,935

REINFORCED SYRINGE BODY

Merit Medical Systems, In...

1. A syringe body configured for use in connection with a high-pressure inflation device, the syringe body comprising:a first wall defining a fluid reservoir, the fluid reservoir configured to receive a plunger;
a second wall defining a distal end of the fluid reservoir, the second wall comprising:
at least one stiffening rib; and
an inlet/outlet port disposed in the second wall,
wherein a distal end of the first wall extends distally relative to the second wall along a circumference of the second wall forming an annular stiffening lip,
wherein the second wall defines an interior surface of the fluid reservoir extending between the first wall and the inlet/outlet port, and
wherein the at least one stiffening rib extends inward of the annular stiffening lip along an exterior surface of the second wall.

US Pat. No. 10,426,934

BALLOON CATHETER

ABBOTT CARDIOVASCULAR SYS...

1. A balloon catheter comprising:an outer shaft including a hypotube and a monolithic single-layer distal outer member of polymer material, the outer shaft having an inflation lumen defined therethrough, wherein the monolithic single-layer distal outer member is necked to a reduced diameter along an entire length thereof with the polymer material consisting essentially of polymer chains in a linear orientation, wherein a proximal end of the monolithic single-layer distal outer member is coupled to the hypotube, and wherein a distal section of the hypotube comprises a skive defined by a first angled cut, an axial cut, and a second angled cut;
a balloon in fluid communication with the inflation lumen, the balloon having a proximal balloon shaft coupled to a distal end of the monolithic single-layer distal outer member; and
a monolithic inner tubular member having a guidewire lumen defined therethrough, the monolithic inner tubular member extending distally from a proximal port in the monolithic single-layer distal outer member through the balloon to form a tip.

US Pat. No. 10,426,933

CATHETER HAVING MONOLITHIC MULTILAYER DISTAL OUTER MEMBER

ABBOTT CARDIOVASCULAR SYS...

1. A balloon catheter, comprising:an outer shaft including a hypotube and a monolithic multilayer distal outer member of polymer material, the outer shaft having an inflation lumen defined therethrough, the monolithic multilayer distal outer member having a proximal end portion and a distal end portion, the monolithic multilayer distal outer member having an inner layer comprising a first polymer having a tensile strength greater than 8,000 psi and an outer layer comprising a second polymer having a flexural modulus of less than 130,000 psi at room temperature, wherein a proximal end of the monolithic multilayer distal outer member is coupled to the hypotube, wherein the monolithic multilayer distal outer member is necked to a reduced diameter along an entire length thereof with the polymer material consisting essentially of polymer chains in a linear orientation;
a balloon in fluid communication with the inflation lumen, the balloon having a proximal balloon shaft coupled to a distal end of the monolithic multilayer distal outer member; and
an inner tubular member having a guidewire lumen defined therethrough, the inner tubular member extending distally from a proximal port in the proximal end portion of the monolithic multilayer distal outer member through at least a portion of the balloon.

US Pat. No. 10,426,932

METHOD AND APPARATUS FOR INTRODUCING AN INTRAVENOUS CATHETER

1. An I.V. catheter insertion assembly comprising:a) a tubular member that is transparent and has a body, a first end, and a second end, wherein the first end is located at a proximal end of the body and is mammillated, and wherein the second end is located at a distal end of the body;
b) a plunger assembly slidable within the body of said tubular member, the plunger assembly having a chamber that is continuous and transparent, and the plunger assembly having a finger paddle and a control knob at a distal end of the plunger assembly;
c) said chamber of the plunger assembly in fluid communication with said control knob at the distal end of the plunger assembly;
d) a needle base and a sealing member that is air-tight, wherein the sealing member is at a proximal end of the chamber, the sealing member in slidable vacuum sealing contact along an interior surface of the body of the tubular member;
e) a needle that is elongated, beveled, and tubular, the needle embedded within said needle base and extending therefrom with said needle in fluid communication with said chamber, and the needle having a needle tip;
f) an I.V. catheter comprising a cannula, wherein the cannula is flexible, transparent, and is an I.V. cannula, the cannula having a cannula tip and a hub that is transparent, the hub attached to said first end of the tubular member with said needle operable to pass longitudinally through said cannula;
g) the plunger assembly operable to move within the tubular member between a neutral position and one or more retracted positions, wherein in the neutral position the sealing member and needle base are at or near a junction of the first end of the tubular member and the body, and wherein the needle passes longitudinally through said cannula and with the needle tip extending exterior to said cannula tip, and wherein in the one or more retracted positions the needle tip is retracted to an interior of the cannula;
h) a fluid passage formed in a space between said needle and said cannula when the needle passes longitudinally through said cannula; and
i) wherein when moving to the one or more retracted positions, retraction of the plunger assembly causes a vacuum in the fluid passage and suction on the cannula tip, said suction visibly drawing blood into the fluid passage and along a longitudinal length of the fluid passage enabling a user to verify that the cannula has entered a blood vessel.

US Pat. No. 10,426,931

CATHETER PLACEMENT DEVICE AND METHOD

C. R. Bard, Inc., Murray...

1. An insertion tool for inserting a catheter into a body of a patient, comprising:a housing;
a needle having a proximal portion in the housing and a distal portion extending from a distal end of the housing;
a catheter advancement assembly, comprising:
the catheter coaxially disposed over the needle, the catheter having a proximal end in the housing and a distal end extending from the distal end of the housing in a catheter first position; and
a handle coupled to the proximal end of the catheter, the handle extending laterally from the housing in the catheter first position, the handle slidable with respect to the housing to transition the catheter distally from the catheter first position to a catheter second position; and
a guidewire advancement assembly, comprising:
a guidewire disposed at least partially in a lumen of the needle; and
a slide member coupled to the guidewire, the slide member slidable with respect to the housing to transition the guidewire relative to the needle.

US Pat. No. 10,426,929

INTEGRATED PERIPHERAL INTRA-VENOUS CATHETER WITH IMPROVED EXTENSION TUBE PORT PROBE ACCESS

Becton, Dickinson and Com...

1. A vascular access device, comprising:a catheter for insertion into a biological site;
a catheter adapter having a catheter hub and a side port coupled to the catheter hub, the catheter hub having a first end operably coupled to the catheter, a second end opposite the first end, and an internal wall defining an internal fluid passageway therebetween, the side port having another internal wall defining a lumen in fluid communication with the internal fluid passageway, wherein the other internal wall of the side port comprises a distal surface and a proximal surface opposite the distal surface, wherein the side port further comprises a protrusion extending outwardly from the proximal surface; and
a septum disposed within the internal fluid passageway;
wherein the protrusion is configured to deflect a probe entering the catheter hub from the side port towards the first end of the catheter hub such that the probe contacts the internal wall at a contact angle between 90 degrees and 180 degrees.

US Pat. No. 10,426,927

TELESCOPING CATHETERS AND METHODS FOR USE

CLPH, LLC, Palo Alto, CA...

1. An apparatus for performing a medical procedure within a patient's body, comprising:a first elongate member comprising a first proximal portion, a first distal portion sized for introduction into a patient's body and including a first distal end, and a lumen extending between the first proximal portion and the first distal end;
a second elongate member comprising a second proximal portion, a second distal portion slidably received within the lumen and including a second distal end, the second elongate member being movable relative to the first elongate member between a retracted position and a distal position where the second distal end extends distally from the first distal end; and
cooperating magnetic elements on the first and second distal ends at locations to secure the second elongate member at the retracted position using a magnetic attraction between the magnetic elements, the magnetic attraction being such that a predetermined force disengages the magnetic elements to allow the second elongate member to be directed from the retracted position towards the extended position,
wherein the first distal end terminates at a first distal tip, and wherein the magnetic elements comprise a first magnetic element on the first distal tip at least partially surrounding an outlet of the lumen and a second magnetic element on the second distal end such that when the second distal end is directed to the retracted position, the second magnetic element abuts the first distal tip, and
wherein the second elongate member terminates at a second distal tip, and wherein the second magnetic element comprises an enlarged member on the second distal tip having a cross-section larger than the outlet of the lumen such that the second magnetic element contacts the first distal tip surrounding the outlet.

US Pat. No. 10,426,924

PLACEMENT AID FOR PLACING A CATHETER FOR DIABETICS

1. A placement aid for placing a catheter and a sensor wire into a body comprising:a placement device;
a replacement device with a main body, a placement needle, a catheter and a sensor wire;
wherein the replacement device is arranged in the placement device in an interchangeable and replaceable manner,
wherein the placement needle is coupled to the main body,
wherein the placement needle and the catheter are arranged with regard to each other in such a way that the placement needle is arranged within the catheter, and that a tip of the placement needle protrudes from a proximal end of the catheter along a puncturing direction so that upon placement of the catheter along the puncturing direction, the tip of the placement needle penetrates a skin in order to produce a skin opening through which the catheter can be guided up to a subcutaneous end position, and
wherein the sensor wire is coupled to the placement needle in such a way that upon placement of the catheter along the puncturing direction, the sensor wire is arranged in the placement needle and that, upon reaching the subcutaneous end position of the catheter, the placement needle can be removed from the catheter against the puncturing direction and the sensor wire remains in the catheter; and
a holding-down rod which is arranged in the placement needle in a displaceable manner,
wherein the holding-down rod is designed to frictionally press the sensor wire against the placement needle, and
wherein the holding-down rod is further arranged at the main body in a movable manner along the puncturing direction such that, upon placement of the catheter along the puncturing direction, the placement needle, the sensor wire and the holding-down rod can jointly be advanced up to the subcutaneous end position of the catheter and such that, upon reaching the subcutaneous end position of the catheter, the holding-down rod can be withdrawn from the catheter against the puncturing direction.

US Pat. No. 10,426,923

CATHETER TIP ASSEMBLED WITH A SPRING

Medinol Ltd., Tel Aviv (...

20. A flexible catheter, comprising:a longitudinal catheter body extending from a proximal end to a distal end; and
a flexible catheter tip located at said distal end of said longitudinal catheter body, said flexible catheter tip including a spring element having a proximal end and a distal end that is a distal-most end of the flexible catheter, said spring element defining an inner lumen having n inner luminal diameter and an outer diameter;
wherein said spring element is a wire coil having pitch space between two or more coils in a first region and tightly packed coils in a second region, said second region being distal of said first region,
wherein said wire coil having a decreasing cross-sectional diameter from the proximal end of the spring element to the distal end of the spring element, and
wherein said inner luminal diameter tapers at a lesser rate than the outer diameter of the spring element.

US Pat. No. 10,426,922

MEDICAL APPARATUS AND METHOD OF MAKING THE SAME

1. A catheter assembly comprising:a catheter having a proximal end and a distal end;
an expandable device releasably attached to the catheter near the distal end, wherein the expandable device is maintained in a compressed state for endoluminal delivery;
a tip fixedly secured to the distal end of and generally coaxial with the catheter; and
a bridge member generally coaxial with the catheter and disposed in a gap between the expandable device and the tip, the bridge member being positioned distally to the expandable device and axially compressed between the tip and the expandable device such that the bridge member fills the gap between the expandable device and the tip with the expandable device maintained in the compressed state, such that the bridge member is configured to fill the gap between the expandable device and the tip during endolum inal delivery of the catheter assembly.

US Pat. No. 10,426,920

INTEGRATED CATHETER SYSTEM

BOSTON SCIENTIFIC SCIMED,...

1. A guide catheter, comprising:an inner layer defining a lumen extending therethrough;
a reinforcing braid disposed about the inner layer, the reinforcing braid comprising a plurality of wires interwoven with each other in an alternating over and under fashion;
a plurality of steering wires interwoven through the reinforcing braid; and
an outer layer disposed about the reinforcing braid;
wherein at least a portion of the reinforcing braid is embedded within the outer layer.

US Pat. No. 10,426,918

FLUSHABLE CATHETERS

Hollister Incorporated, ...

1. A catheter assembly comprising:a catheter shaft having proximal and distal end portions; and
a funnel assembly fixedly secured to the distal end portion of the catheter shaft, wherein
a drainage portion is defined through the funnel assembly and the funnel assembly includes
a groove along at least a portion of an outer perimeter of the funnel assembly and/or
a shaft channel defined through the funnel assembly, with the groove and/or the shaft channel being configured to receive at least a portion of the catheter shaft for securing said at least a portion of the catheter shaft to the funnel assembly for disposal,
the drainage portion is positioned between a pair of lateral portions,
each lateral portion includes a front face and a rear face, and
the groove is defined between the front and rear faces.

US Pat. No. 10,426,917

SYSTEM AND METHOD FOR MANUFACTURING VARIABLE STIFFNESS CATHETERS

Stryker Corporation, Kal...

1. A system for manufacturing a catheter, comprising:a first material feeder coupled to a first material source;
a second material feeder coupled to a second material source;
a thermally controlled mixer coupled to the first and second material feeders, wherein the first material feeder is configured to feed a first material from the first material source into the mixer at a first material feed rate, and the second material feeder is configured to feed a second material from the second material source into the mixer at a second material feed rate, such that the first and second materials are combined in the mixer to form a compound material that varies in content as a function of the respective first and second materials, and of the first and second material feed rates;
a catheter formation mandrel having a longitudinal axis, the mandrel being controllably rotatable about the longitudinal axis at a mandrel rotation rate;
an extruder operatively coupled to the mixer and having an output nozzle configured to apply compound material from the mixer onto the catheter formation mandrel; and
a control system comprising one or more processors that control one or more of the first material feed rate, second material feed rate, and mandrel rotation rate, respectively, so as to enable formation of a catheter having a variable stiffness profile along a length of the catheter,
wherein the extruder is configured to apply an extrusion of compound material from the mixer onto the catheter formation mandrel such that the extrusion winds around the mandrel forming adjacent loops of compound material on the catheter formation mandrel.

US Pat. No. 10,426,916

METHOD OF USING AUTONOMIC NERVE FLUCTUATIONS AND SYSTEM USING THE SAME

PANASONIC INTELLECTUAL PR...

1. A method comprising:obtaining, by a processor and from a camera, information about a period of a fluctuation cycle in an autonomic nerve of a user; and
causing, by the processor, to repeat, in a same period as the period of the fluctuation cycle in the autonomic nerve, a process that includes inducing a point of gaze of the user to move along an optical axis of the user in a direction away from the user, and inducing the point of gaze of the user to move along the optical axis of the user in a direction to approach the user, according to the obtained information;
wherein
the period of the fluctuation cycle in the autonomic nerve is a period of a fluctuation cycle in a diameter of a pupil of the user.

US Pat. No. 10,426,915

SURGICAL INSTRUMENT HAVING AN INTEGRATED LOCAL ANESTHETIC DELIVERY SYSTEM

1. A surgical instrument configured for locally delivering anesthetic while implanting a mechanism configured for treating female urinary incontinence, the surgical instrument comprising:a handle portion defining a reservoir;
a longitudinally curved sling- and anesthetic-delivery incising tube in fluid communication with the reservoir, and configured to:
form a path in the abdomen of the patient;
move a sling through pelvic fascia of the patient; and
position the sling between the patient's urethra and vaginal wall;
an anesthetic delivery actuator that is connected to a biasing member, in ratcheting engagement with a plunger disposed within the reservoir and configured to move the anesthetic delivery actuator; an actuator guard disposed on the handle portion and configured to prevent inadvertent actuation of the anesthetic delivery actuator;
the biasing member;
the plunger; a local anesthetic inlet tube that is partially housed within the handle portion, terminates at an inlet port sealed by a valve cap that provides pressure release without fluid release, and is in fluid communication with the reservoir; and
the valve cap;
wherein:
the surgical instrument is configured to locally deliver the anesthetic while assisting the surgeon with forming the path through, moving the sling within, and implanting the sling in, the patient's abdomen.

US Pat. No. 10,426,913

APPARATUS AND METHOD FOR MONITORING NITRIC OXIDE DELIVERY

Mallinckrodt Hospital Pro...

1. An apparatus to deliver therapeutic gas to a patient, the apparatus comprising:a first inlet to be placed in fluid communication with a therapeutic gas supply providing a continuous flow of nitric oxide at a therapeutic gas supply concentration;
a second inlet to be placed in fluid communication with a breathing gas delivery system providing a continuous flow of a breathing gas to the patient;
a therapeutic gas injector module to be placed in fluid communication with the first inlet and the second inlet to provide a combined continuous flow of breathing gas and therapeutic gas;
an outlet in fluid communication with the therapeutic gas injector module to supply the combined continuous flow of breathing gas and therapeutic gas to the patient;
a control circuit including a first flow sensor to measure the continuous flow of breathing gas from the breathing gas delivery system and a second flow sensor to measure the continuous flow of therapeutic gas, wherein the control circuit determines a calculated dose of nitric oxide based on the measured flow of breathing gas and either the measured flow of therapeutic gas or a known continuous flow of therapeutic gas; and
a display in communication with the control circuit that provides a visual and/or numeric indication of the calculated dose of nitric oxide, wherein the visual and/or numeric indication of the calculated dose of nitric oxide is provided as a percentage of a desired delivery concentration to be delivered to the patient, wherein the desired delivery concentration is set by a user; and
wherein the visual and/or numeric indication of the calculated dose of nitric oxide as the percentage of the desired delivery concentration is indicated on the display as being in one of a target delivery region, an under-delivery of nitric oxide region, and an over-delivery of nitric oxide region.

US Pat. No. 10,426,912

ZONE HEATING FOR RESPIRATORY CIRCUITS

17. A medical tube comprising:a first segment comprising one or more heater wires;
a second segment comprising one or more heater wires;
a connection circuit adapted to connect the first and second segments, the connection circuit comprising a diode; and
a controller,
wherein each of the first and second segments further comprises a spirally wound elongate hollow body and a spirally wound elongate bead member, the spirally wound elongate hollow body forming at least in part an elongate tube comprising a longitudinal axis and a lumen extending along the longitudinal axis, the elongate bead member forming at least a portion of the lumen and providing support for the elongate hollow body, and
wherein the controller is adapted to selectively switch between a first mode in which the controller provides power to the first segment, and a second mode in which the controller provides power to the first and second segments,
wherein a heater circuit comprising the one or more heater wires of the first and second segments is independent of another heater circuit that heats another tube.

US Pat. No. 10,426,911

RESPIRATORY THERAPY CONDENSATION ADAPTOR

VAPOTHERM, INC., Exeter,...

1. An adaptor for coupling a tracheostomy tube to a source of humidified breathing gas, the adaptor comprising:a housing having an interior surface, an exterior surface, and a breathing gas port for receiving a flow of humidified breathing gas from the source, the breathing gas port extending from the exterior surface to the interior surface;
a tracheostomy tube connection device positioned within the housing, the tracheostomy tube connection device including an input port for receiving the flow of humidified breathing gas from the breathing gas port and an output port for coupling with the tracheostomy tube, the tracheostomy tube connection device having an internal surface defining a breathing gas passage and an external surface spaced from the interior surface of the housing to create a condensation passage wherein the condensation passage comprises a bottom end, and wherein the condensation passage is configured such that condensation flows towards the bottom end and exits the adaptor;
a baffle positioned between the breathing gas port and the input port to cause controlled condensation from the flow of humidified breathing gas by disrupting the flow of humidified breathing gas; and
at least one projection, positioned within the housing, to space the tracheostomy tube connection device from the interior surface of the housing.

US Pat. No. 10,426,909

NASAL RESPIRATORY ASSEMBLY AND METHODS OF USE

1. A nasal respiratory assembly for delivering a therapeutic treatment to a patient comprising:a) a mask having a top surface and a base, wherein said mask is configured with an exhaust port having a one-way valve positioned on said top surface;
b) a first rotatable intake port and a second rotatable intake port positioned on either side of said top surface, wherein said first and said second rotatable intake ports further comprises a directing means that directs pressurized gas from entering said patient's nasal cavities directly, and wherein said directing means is one or more louvered vents;
c) a hose having a first end and a second end adapted to be received by said first and second intake ports, and at least a third end; and
d) a rotatable medication delivery port provided on said hose and positioned proximal to at least one of said intake ports; and
wherein said therapeutic treatment is not delivered directly into the patient's nasal cavities.

US Pat. No. 10,426,907

METHOD AND SYSTEM FOR CONTROLLING A DRUG DOSING DEVICE

1. A method for controlling a drug dosing device for administering a drug to a patient, the method comprising:determining a quantity of the drug administered to the patient from the drug dosing device via a drug quantity determination device;
measuring a concentration of the drug in the gas exhaled by the patient as a first patient value via a concentration determining device;
providing a control system configured for:
carrying out a simulation calculation, in which a second patient value is calculated from the administered quantity of the drug, taking into account a parameter;
calculating a simulated first patient value in the simulation calculation, taking into account the parameter;
comparing the simulated first patient value to the measured first patient value;
adapting the parameter on the basis of the comparison; and
generating a control signal based on the second patient value, wherein the drug dosing device adapts the quantity of the drug administered to the patient based on the control signal, wherein the simulation calculation comprises a compartment model carried out based on:
blood circulation forming a first compartment;
a second compartment being taken into account, for which a concentration of the drug is calculated;
a third compartment being taken into account, for which a concentration of the drug is calculated;
the drug passing from the first compartment into the second compartment at a first rate;
the drug passing from the second compartment into the first compartment at a second rate;
the drug passing from the first compartment into the third compartment at a third rate;
the drug passing from the third compartment into the first compartment at a fourth rate;
the concentration of the drug in the breathing gas forming the first patient value being calculated such that a passage of the drug from the first compartment into the breathing gas takes place at a breathing gas rate; and
the drug being broken down from the first compartment at an elimination rate, which is the parameter, wherein the simulation calculation is carried out such that a passage of the drug from the lung into the breathing gas is calculated by a time lag element of the first order, so that an equation:
?1+k10·c1=K·k10·cp applies to the concentration (c1) of the drug in the breathing gas and a change to the concentration over time (?1), wherein cp is the concentration of the drug in the blood circulation and K and k10 are constants.

US Pat. No. 10,426,906

VENTILATOR MONITORING AND CONTROL

Mayo Foundation for Medic...

25. A computer-implemented patient information provisioning system, comprising:one or more mechanical ventilators for treating patients in a healthcare facility;
an interface operating on a computer processor system programmed to identify, as key words, terms likely to occur in electronic medical records that are determined to indicate presence of acute lung injury or acute respiratory distress syndrome, and obtain (a) data about operating parameters of the one or more mechanical ventilators, including information about the location(s) of the one or more mechanical ventilators, (b) information for electronically contacting particular caregivers who correspond to patients served by the one or more mechanical ventilators and are identified for contact based on a determination of what caregiver is currently assigned responsibility for a location in the healthcare facility that currently needs action by a caregiver, and (c) data from a central electronic medical records system operated by the healthcare facility, wherein the patient information provisioning system is programmed to automatically query written textual descriptions by caregivers in electronic medical records of the electronic medical record system to determine whether trigger terms in the records indicate that one or more particular patients under care have acute lung injury or acute respiratory distress syndrome;
an electronic patient evaluator to use the data about the current operating parameters of the one or more mechanical ventilators and the data from the central electronic medical records system to
(1) adjust an operational value for a first mechanical ventilator, of the one or more mechanical ventilators, from a normal value that is used for patients who do not have acute lung injury or respiratory distress syndrome, based on determining that a dangerous condition exists for a first patient as a combination of
(a) the first patient's electronic medical record having one or more key words that are indicative of acute lung injury or acute respiratory distress syndrome, and
(b) the first mechanical ventilator having a current value inconsistent with treatment of someone with acute lung injury or acute respiratory distress syndrome;
(2) determine that a potentially dangerous condition exists for the first patient based on a measured value for the first mechanical ventilator being excessive compared to the adjusted operational value; and
(3) identify that the first patient is receiving an inappropriate low tidal volume from the first mechanical ventilator by determining that a measured value for the first mechanical ventilator is excessive compared to the adjusted operational value; and
an alert module to provide, for transmission to one or more caregivers who are remote from the first mechanical ventilator, a notification of the identified dangerous condition.

US Pat. No. 10,426,905

METHODS AND SYSTEMS FOR IMPROVING AIRWAY PATENCY

SOMNICS, INC., Zhubei, H...

17. Apparatus for improving airway patency of a patient having an oral cavity, a hard palate, a soft palate, a tongue, lips, and an airway, the apparatus comprising: an oral device positionable in the oral cavity, the oral device comprising one or more ports through which negative pressure is applied to provide a continuous pathway for pressure delivery from the lips to the soft palate when the oral device is placed in the oral cavity, wherein the oral device is configured to apply negative pressure to generate a seal between the soft palate and a posterior region of the tongue to isolate the airway from the oral cavity, and wherein the oral device comprises a tongue constraint having a superior surface and an inferior surface, the surfaces being configured to maintain a clear region between a medial region of the tongue and the hard palate.

US Pat. No. 10,426,904

VOLUME REFLECTOR STATUS INDICATOR FOR ANESTHESIA SYSTEM

Maquet Critical Care AB, ...

1. An anesthesia system having a volume reflector, a breathing circuit, a processing unit, and a display operatively connected to said processing unit, wherein said processing unit is configured to provide a status indicator on said display for gas in said volume reflector, said status indicator including a real-time graphical representationof a driving gas of said volume reflector and a patient gas in said volume reflector; and
a flow of gas and a direction of said flow in said volume reflector;
wherein said status indicator comprises a graphical representation of adjacent gas pillars representing said driving gas and said patient gas in operation in said volume reflector, and said graphical representation further includes a representation of a present extent of said driving gas pillar and said patient gas pillar in said volume reflector during both an inhalation and an exhalation of a breathing cycle.

US Pat. No. 10,426,902

SYSTEMS FOR LAPAROSCOPIC SURGERY

1. A surgical humidification apparatus comprising:a heater base configured to contact a humidification chamber in use, the humidification chamber adapted to hold a volume of water and having an inlet and an outlet, the inlet in fluid communication with a gases source to receive gases from the gases source in use, the heater base configured to heat the water in the humidification chamber to create vapor to humidify gases passing through the humidification chamber from the inlet to the outlet in use; and
a controller configured to determine a low water or a no water condition of the humidification chamber based at least in part on an increase in power supplied to the heater base.

US Pat. No. 10,426,901

SYRINGE CAP HAVING REUSE PREVENTION STRUCTURE

1. A syringe cap having a reuse prevention structure, the syringe cap comprising:a fixed body (20) with a spiral protrusion (22) on an inner circumferential surface thereof, into which a dispensing tip (11) of a syringe barrel (10) is fitted, and whose bottom is coupled to the syringe barrel (10) by a fusion welding portion (21);
a separable body (30) with a spiral groove (31) on a lower part of an outer circumferential surface thereof, the spiral groove (31) being spirally engaged with the spiral protrusion (22) provided on the inner circumferential surface of the fixed body (20);
a rubber packing (40) fitted in the separable body (30) to seal and block the dispensing tip (11) of the syringe barrel (10) coupled to the fixed body (20); and
a reuse prevention cover (50) fitted over the fixed body (20) and the separable body (30) to cover the fixed body (20) and the separable body (30),
wherein the reuse prevention cover (50) includes:
an upper body (51) fitted over the separable body (30) to cover an outer surface of the separable body (30);
a lower body (52) fitted over the fixed body (20) to cover an outer surface of the fixed body (20), and positioned below a lower end of the upper body (51) such that a top of the lower body (52) is spaced apart from a bottom of the upper body (51); and
a connection breakable portion (53) which integrally connects the upper body (51) and the lower body (52) by connecting the bottom of the upper body (51) to the top of the lower body (52), and is broken by rotating the upper body (51) relative to the lower body (52) in a direction to separate the bottom of the upper body (51) from the top of the lower body (52), such that the separable body (30) covered with the upper body (51) is separated from the fixed body (20) to open the fixed body (20), and
wherein the spiral protrusion (22) of the fixed body (20) includes a tapered first pushing slope (23), and the spiral groove (31) of the separable body (30) includes a second pushing slope (32) corresponding to the first pushing slope (23) such that when rotating the upper body (51) of the reuse prevention cover (50) in one direction relative to the lower body (52) in a state of pushing the upper body (51) toward the lower body (52), the upper body (51) is pushed up by the lower body (52), thereby being easily broken due to breaking of the connection breakable portion (53) connecting the upper body (51) and the lower body (52) to each other.

US Pat. No. 10,426,900

AUTOMATIC INJECTION DEVICE

TERUMO KABUSHIKI KAISHA, ...

1. A method for measuring an amount of pain comprising:positioning a needle adjacent a non-human animal which is under anesthesia;
automatically inserting the needle at a controlled puncture speed into skin of the non-human animal by an automatic needle puncture device; and
measuring a muscle action potential of a muscle portion of the non-human animal produced by the insertion of the needle, the muscle action potential being measured from insertion start, at which the insertion of the needle into the skin is started, to insertion stop, at which the insertion of the needle into the skin is stopped,
whereby the measured muscle action potential indicates a measurement of the amount of pain.

US Pat. No. 10,426,899

MEDICAL DEVICE ASSEMBLY

Becton, Dickinson and Com...

1. A medical device assembly comprising:a fluid storage container having a visual indicator including three separate colored strips comprising a first colored stripe disposed closest to an opening of the fluid storage container, a second colored stripe disposed proximally adjacent to the first colored stripe, and a third colored stripe disposed proximally adjacent to the second stripe;
a device having a hub including a sidewall having an inside surface defining a cavity, an open proximal end, and a distal end having an opening therethrough in fluid communication with the cavity; the hub of the device attaches to the fluid storage container;
a first indicating element having a distal end attached to the distal end of the hub and a free proximal end extending into the cavity, the first indicating element forming a peripheral recess with the sidewall of the hub; and
a second indicating element disposed in the cavity of the hub including an open proximal end, an open distal end and a body extending from the open proximal end of the second indicating element to the open distal end, the body having an inside surface defining a hollow interior for enveloping the first indicating element to permit the body to enter the recess of the hub upon application of a force to the hub in a proximal direction relative to the fluid storage container, wherein the hub attaches to the fluid storage container such that visibility of the second stripe and the third stripe indicates optimal engagement of the hub to the fluid storage container.

US Pat. No. 10,426,898

RETRACTABLE NEEDLE ASSEMBLIES

Owen Mumford Limited, (G...

1. A retractable needle assembly comprising:a body portion;
a needle having a patient end and being movable between an operational position in which the needle extends along a longitudinal needle axis with the patient end projecting forwardly from the body portion, and a safe position in which the patient end is retracted into the body portion;
a deflector element rotatable about a deflector rotary axis generally perpendicular to the longitudinal needle axis to move the needle to its safe position, and
a manually operated deflector lever connected to or forming part of the deflector element, the manually operated deflector lever projecting from the body portion and intersecting a plane perpendicular to the deflector rotary axis and containing the longitudinal needle axis, the manually operated deflector lever rotates about the deflector rotary axis, from a first position perpendicular to the longitudinal needle axis to a second position parallel to the longitudinal needle axis, to fully retract the needle.

US Pat. No. 10,426,897

CONTAINER HOLDER ASSEMBLY FOR A MEDICAMENT DELIVERY DEVICE AND MEDICAMENT DELIVERY DEVICE COMPRISING THE CONTAINER HOLDER ASSEMBLY

Carebay Europe LTD, Slie...

1. Container holder assembly for a medicament delivery device, which container holder assembly comprises;a housing part, fixedly mounted relative to a longitudinally elongated housing;
a container holder for accommodating a medicament container, which container holder is longitudinally movable relative to the housing part from a distal, initial position to a proximal, end position;
a spring-biased needle guard, coaxial with the container holder and releasably connected with the container holder, and longitudinally movable relative to the housing part between an extended position and a retracted position;
wherein the housing part is coaxially arranged between the container holder and the needle guard,
wherein the housing part comprises a first longitudinal slit through which the needle guard is connected with the container holder,
wherein the needle guard is connected with the container holder by a first connecting member of the needle guard radially biasing a resilient second connecting member of the container holder,
wherein the needle guard is configured to disconnect from the container holder upon movement from the extended position to the retracted position, and
wherein, when the needle guard is connected to the container holder, the second connecting member is radially biased into engagement with a holding member of the housing part, such that the container holder is prevented from longitudinal movement relative to the housing part.

US Pat. No. 10,426,896

MEDICINE INJECTION AND DISEASE MANAGEMENT SYSTEMS, DEVICES, AND METHODS

Bigfoot Biomedical, Inc.,...

1. A pen cap for an insulin pen comprising:one or more sensors adapted to detect a position of a plunger within the insulin pen;
a user interface comprising one or more user-selectable icons or buttons adapted to announce a meal or an intent to have a meal;
a sensor adapted to detect a characterization of the insulin pen or a type of insulin in the insulin pen;
a memory to store information about different types of insulin pens or different types of insulin; and
a processor to determine the type of insulin pen or the type of insulin, wherein the processor is configured to change the user interface dependent on the type of insulin pen or the type of insulin, wherein some types of insulin or insulin pens result in a user-interface that does not include any user-selectable icons or buttons adapted to announce a meal or an intent to have a meal.

US Pat. No. 10,426,895

DRIVE MECHANISM AND DRUG DELIVERY DEVICE HEREWITH

Sanofi, Paris (FR)

1. A drive mechanism for a drug delivery device, the mechanism comprising a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member into a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member when in a decoupled state, and a spring biasing the clutch into the coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring, wherein the clutch comprises a first ring of crown teeth on the drive member and a second ring of corresponding crown teeth on the driven member with each crown tooth having in the clockwise and the anti-clockwise direction different ramped tooth angles such that the teeth are allowed to override each other in the de-coupled state of the clutch with a different resistance in the clockwise and the anti-clockwise direction, wherein the drive member is formed of polybutylene terephthalate (PBT), polyoxymethylene (POM), or polycarbonate (PC) and the rotatable driven member is formed of PBT, POM or PC, and a coefficient of friction (?) between the teeth on the drive member and the teeth on the driven member is between 0.05 and 0.3, and the teeth on the drive member and the teeth on the driven member have a surface roughness (Ra) of 0.2?Ra?10 micrometers.

US Pat. No. 10,426,894

DRUG DELIVERY DEVICE WITH INDICATOR

INSULET CORPORATION, Act...

1. An apparatus, comprising:a drug container configured to hold a liquid drug;
a plunger positioned in the drug container;
a drive system coupled to the plunger, the drive system configured to advance the plunger to expel a portion of the liquid drug from the drug container for delivery to a patient, the drive system comprising one or more spherical elements and a drive spring;
a Hall effect sensor positioned adjacent to the drug container; and
a controller coupled to the Hall effect sensor,
wherein the Hall effect sensor is configured to measure a varying magnetic field caused by the one or more spherical elements passing the Hall effect sensor,
wherein the Hall effect sensor is configured to generate a signal indicative of the measured varying magnetic field,
wherein the controller receives the signal generated by the Hall effect sensor and determines a count of a number of the one or more spherical elements that pass the Hall effect sensor.

US Pat. No. 10,426,893

DRUG DELIVERY DEVICE WITH THREADED HOUSING AND PISTON, AND METHOD FOR MANUFACTURING THE SAME

Sanofi, Paris (FR)

1. A drug delivery device for selecting and dispensing a number of user variable doses of a medicament, the drug delivery device comprising: a housing defining a longitudinal axis and having a tubular portion with an inner thread, a piston rod having a threaded portion and a distal end, and a bearing having a distal face and a proximal face, wherein the bearing comprises a retaining stem protruding from the proximal face, wherein the piston rod comprises a distal portion having an outer diameter which is smaller than an inner diameter of the inner thread of the tubular portion, and, a retaining clip engaging the retaining stem at a distal end of the piston rod, and wherein an axial length of the tubular portion is smaller than or equal to an axial distance between the proximal face of the bearing and the distal end of the threaded portion of the piston rod.

US Pat. No. 10,426,891

DISPOSABLE CASSETTE FOR STORING AND DELIVERING A MEDICAL DRUG

1. An injector device comprising:a housing defining a cavity having a disposable cassette arranged therein, said housing comprising a movable lid allowing the disposable cassette to be inserted into or removed from the cavity,
a movable sledge configured to operate a valve block of the disposable cassette arranged in the cavity, and
a plunger activator arranged in abutment with a plunger of a cartridge of the disposable cassette arranged in the cavity, the plunger activator being configured to operate the plunger in order to cause a medical drug to be delivered,
wherein the disposable cassette comprises:
the cartridge containing the medical drug,
a waste reservoir arranged to receive waste liquid and/or gas,
an injection needle or an injection needle mounting interface for mounting an injection needle arranged to deliver the medical drug, and
the valve block being movable between a first position and a second position, the first position establishing a fluid passage between the cartridge and the waste reservoir, while preventing fluid flow from the cartridge to the injection needle or the injection needle mounting interface, and the second position establishing a fluid passage between the cartridge and the injection needle or the injection needle mounting interface, while preventing fluid flow from the cartridge to the waste reservoir,
wherein the cartridge, the waste reservoir, the valve block and at least part of the injection needle or the injection needle mounting interface are arranged inside a cassette housing of the disposable cassette, and wherein the valve block is operable to be moved between the first position and the second position without a user operating the disposable cassette coming into direct contact with parts arranged inside the cassette housing.

US Pat. No. 10,426,890

DRUG DELIVERY DEVICE

Sanofi-Aventis Deutschlan...

1. A drug delivery device comprising:a primary drug delivery assembly with a primary dose dial sleeve configured to move proximally in a helical movement during setting of a dose of a primary medicament contained in a primary reservoir of the primary drug delivery assembly and a secondary drug delivery assembly with a secondary drive sleeve configured to move in a proximal direction in a helical movement during setting of a dose of a secondary medicament contained in a secondary reservoir of the secondary drug delivery assembly
a selection switch movable between a first position, a second position, and a third position, wherein the first position is an intermediate position between the second position and the third position; and
a clutch connected to the selection switch such that movement of the selection switch causes rotation of the clutch,
wherein the clutch is configured to engage with and to transfer rotation to the secondary drive sleeve when the selection switch is moved from the first position into the second position such that the dose of the secondary medicament is set and to disengage from the secondary drive sleeve when the selection switch is moved from the first position into the third position such that the dose of the secondary medicament is not set, and
wherein a first engagement element is configured to rotate the primary dose dial sleeve in one direction to set the dose of the primary medicament, wherein the first engagement element is adapted to be engaged by the selection switch such that movement of the selection switch from the first position into the second position and from the first position into the third position causes the first engagement element to rotate the primary dose dial sleeve in the one direction such that a predetermined dose of the primary medicament is set.

US Pat. No. 10,426,889

OPTICAL DISPLACEMENT SENSOR FOR INFUSION DEVICES

DEKA PRODUCTS LIMITED PAR...

1. A medical fluid dispensing apparatus for pumping an infusible medical fluid to the body of a patient, the medical fluid dispensing apparatus comprising:a piston having an encoded pattern associated therewith; and
an optical sensor, wherein the optical sensor is configured to determine the position of the piston, relative to a fiducial position based on the encoded pattern during delivery regardless of whether the encoded pattern associated with the piston repeats.

US Pat. No. 10,426,886

SET OF CONTAINERS FOR USE ON A BLOOD COMPONENT CENTRIFUGAL SEPARATOR

Terumo Kabushiki Kaisha, ...

1. A disposable set of containers for use on a blood component centrifugal separator, said blood component centrifugal separator having a first pump, a second pump and a centrifuge rotor, the disposable set comprising:a separation container adapted to be mounted on the centrifuge rotor and having an inlet port and an outlet port;
a tube in fluid communication with a source of whole blood drawn from a blood donor and in further fluid communication with the separation container and adapted to engage the first pump,
a first container for receiving a predetermined first blood component, among centrifugally separated blood components, together with whole blood, said first container being in fluid communication with the outlet port of said separation container and with the inlet port of said separation container, and
a second tube adapted to engage the second pump and in fluid communication with said first container and said inlet port of said separation container,
a temporary storage container wherein whole blood drawn from the blood donor is temporarily stored, and
a third tube coupled to the temporary storage container further coupled to the outlet port of the separation container and a fourth tube also coupled to the temporary storage container and further coupled between the first container and the second tube and further comprising a fifth tube in fluid communication with said third tube and said first tube such that said second tube is connected to said first tube between said fifth tube and said inlet port of said separation container.

US Pat. No. 10,426,883

SYSTEMS AND METHODS FOR PRIMING HEMODIALYSIS USING MULTIPLE FLUID SOURCES

Baxter International Inc....

1. A hemodialysis system configured to purge air from a blood circuit, the hemodialysis system comprising:a dialyzer;
a dialysis fluid circuit in fluid communication with the dialyzer via dialysis fluid inlet and outlet lines, the dialysis fluid circuit including
a fresh dialysis fluid pump,
a used dialysis fluid pump,
a first balancing unit including (i) a first fresh dialysis fluid chamber operable with the fresh dialysis fluid pump and (ii) a first used dialysis fluid chamber operable with the used dialysis fluid pump, and
a second balancing unit including (i) a second fresh dialysis fluid chamber operable with the fresh dialysis fluid pump and (ii) a second used dialysis fluid chamber operable with the used dialysis fluid pump;
the blood circuit in fluid communication with the dialyzer and including
an arterial line for removing blood from a patient and delivering the blood to the dialyzer,
a venous line for returning blood from the dialyzer to the patient,
a blood pump operable with the arterial line upstream of the dialyzer,
a physiologically acceptable fluid source in fluid communication with the arterial line upstream of the blood pump, and
a drip chamber located along the venous line; and
an air purging scheme wherein, with the dialysis fluid inlet and outlet lines connected to the dialyzer, air is purged from the blood circuit using dialysis fluid or other physiologically acceptable fluid pumped through the dialysis fluid circuit, in combination with dialysis fluid or other physiologically acceptable fluid from the source introduced directly to the blood circuit.

US Pat. No. 10,426,882

BLOOD RINSEBACK SYSTEM AND METHOD

Baxter International Inc....

1. A hemodialysis system configured to return blood to a patient, the hemodialysis system comprising:a dialyzer;
a dialysis fluid circuit in fluid communication with the dialyzer via dialysis fluid inlet and outlet lines, the dialysis fluid circuit including
a fresh dialysis fluid pump,
a used dialysis fluid pump,
a first balancing unit including (i) a first fresh dialysis fluid chamber operable with the fresh dialysis fluid pump and (ii) a first used dialysis fluid chamber operable with the used dialysis fluid pump, and
a second balancing unit including (i) a second fresh dialysis fluid chamber operable with the fresh dialysis fluid pump and (ii) a second used dialysis fluid chamber operable with the used dialysis fluid pump;
a blood circuit in fluid communication with the dialyzer and including
an arterial line for removing blood from a patient and delivering the blood to the dialyzer,
a venous line for returning blood from the dialyzer to the patient,
a blood pump operable with the arterial line upstream of the dialyzer,
a medical fluid source in fluid communication with the arterial line between a patient end of the arterial line and the blood pump,
a drip chamber located along the venous line;
a blood detector operable with the venous line; and
a blood rinseback scheme wherein, with the dialysis fluid inlet and outlet lines connected to the dialyzer, blood is pushed to the patient via the medical fluid being introduced from its source into the arterial line between the arterial line patient end and the blood pump, and flowed through the dialyzer, through the venous drip chamber and to the blood detector along the venous line, where the medical fluid is sensed by the blood detector to indicate an end of the blood rinseback.

US Pat. No. 10,426,872

NERVE REPAIR SCAFFOLDS HAVING HIGH MICROCHANNEL VOLUME AND METHODS FOR MAKING THE SAME

THE REGENTS OF THE UNIVER...

1. A method of making a tissue scaffold for neural tissue growth, the method comprising:admixing (i) a porogen having an average particle size of less than or equal to about 40 ?m with (ii) a polymeric precursor solution comprising a biocompatible and biodegradable polyester polymer precursor and a first solvent, to form a suspension;
contacting a template with the suspension to coat at least one surface of the template;
volatilizing at least a portion of the first solvent to form a coating;
removing the coating from the template; to create a microchannel;
assembling the microchannel inside a sheath with a plurality of other microchannels; and
removing the porogen to form a plurality of porous microchannels disposed within sheath thus creating the tissue scaffold.

US Pat. No. 10,426,871

NANOSTRUCTURE SURFACE COATED MEDICAL IMPLANTS AND METHODS OF USING THE SAME

The Regents of the Univer...

1. A method comprising administering to a subject a composition that comprises a surface or film comprising a vertically oriented array of a plurality of nanotubes or microwells,wherein a bioactive agent is filled into the nanotubes or microwells themselves,
wherein a first end of the array of the plurality of filled nanotubes or microwells is in contact with the surface or film, and
wherein the plurality of nanotubes or microwells is capped with a polymeric erodible capping film to provide for delayed elution of the bioactive agent from within the nanotubes or microwells to the surrounding tissue upon placement in a subject and erosion of the capping film.

US Pat. No. 10,426,870

BIOMATERIALS FOR ENHANCED IMPLANT-HOST INTEGRATION

THE TRUSTEES OF THE UNIVE...

1. A method of treating a subject for ischemia, comprising:(1) providing a patterned biomaterial comprising: at least one cord, formed by embedding cells in a naturally-derived or synthetic scaffolding with a pre-specified architecture and spatially organizing the cells within the scaffolding, wherein the at least one cord comprises endothelial cells; and
(2) implanting the patterned biomaterial into a tissue of the subject, wherein the patterned biomaterial is configured to promote the vascularization of the patterned biomaterial and the tissue of the subject, wherein the structure of the patterned biomaterial has a pre-specified architecture that acts as a template and spatial guidance for the subject's vasculature, such that the subject's vasculature invades and integrates at least partially within the at least one cord.

US Pat. No. 10,426,867

BIOCOMPATIBLE POLYCAPROLACTONE FUMARATE FORMULATIONS

Mayo Foundation for Medic...

1. A scaffold for tissue regeneration, the scaffold comprising:a blend of a polymer having the Formula (I)
H-A1-B-A2-C-A1-B-A2-H  (I)
wherein
A1 is

A2 is

B is —O—X—O— wherein X is selected from the group consisting of ethylene, trimethylene, tetramethylene, pentamethylene, C1-C5alkylethylene,
C1-C5alkyltrimethylene, C1-C5alkyltetramethylene, and C1-C5alkylpentamethylene;
C is

and geometric isomers thereof;
and n is an integer from 1 to 50, and
a polymer having the Formula (II)

wherein
D1 is

D2 is

D3 is

E is —O—X—O— wherein X is selected from the group consisting of propanetriyl, butanetriyl, pentanetriyl, C1-C5alkyl propanetriyl,
C1-C5alkyl butanetriyl, and C1-C5alkyl pentanetriyl;
F is
and geometric isomers thereof;and n is an integer from 1 to 50;
wherein the polymer of Formula (I) comprises 20 wt. % to 80 wt % of the scaffold, and the polymer of Formula (II) comprises 20 wt. % to 80 wt % of the scaffold, and
wherein the polymer of Formula (I) is formed using a first initiator such that B is —O—X—O— wherein X is selected from the group consisting of ethylene, trimethylene, tetramethylene, pentamethylene, C1-C5alkylethylene, C1-C5alkyltrimethylene, C1-C5alkyltetramethylene, and C1-C5alkylpentamethylene, and
wherein the polymer of Formula (II) is formed using a second initiator such that E is —O—X—O— wherein X is selected from the group consisting of propanetriyl, butanetriyl, pentanetriyl, C1-C5alkyl propanetriyl, C1-C5alkyl butanetriyl, and C1-C5alkyl pentanetriyl, and
wherein the first initiator is different from the second initiator.

US Pat. No. 10,426,864

STORAGE APPARATUS HAVING AIR PURIFYING MODULE

SEOUL VIOSYS CO., LTD., ...

1. An air purifying system including,a case having a top surface that is flat, a bottom surface opposite to the top surface, and a side surface connecting the top surface and the bottom surface;
an air inlet arranged on the bottom surface to introduce an air from an exterior of the case to an interior of the case;
a circulation fan arranged inside the case and disposed to receive the air from the air inlet and to generate an air flow moving in a first direction, wherein the top surface of the case is connected to the side surface though a rounded corner structured to cause at least a portion of the generated air flow to change an air flow direction to a second direction, the air moving in the second direction along the top surface,
a light emitting diode part arranged above the air inlet and including a light emitting diode positioned to sterilize the air flow moving in the second direction;
an air outlet positioned to discharge the air to the exterior of the case; and
a collection filter arranged in the case and configured to capture bacteria to increase a sterilization efficiency of the air purifying system,
wherein the first direction is toward the top surface and the second direction is substantially perpendicular to the first direction.

US Pat. No. 10,426,857

SYSTEMS, DEVICES, AND METHODS INCLUDING IMPLANTABLE DEVICES WITH ANTI-MICROBIAL PROPERTIES

Gearbox, LLC, Bellevue, ...

1. An insertable device, comprising:a body structure having an outer surface and an inner surface defining one or more fluid-flow passageways;
circuitry configured to detect one or more microorganisms present proximate at least one of the outer surface, the inner surface, or the one or more fluid-flow passageways; and
one or more actively controllable anti-microbial regions included on at least one of the outer surface or the inner surface, or embedded in the body structure, at least one of the one or more actively controllable anti-microbial regions having a wettability switchable feature configured to actuate between a first anti-microbial state and a second anti-microbial state responsive to detection of at least one microorganism by the circuitry.

US Pat. No. 10,426,851

PROTECTIVE STERILIZATION SYSTEM

1. A protective sterilization system comprising:a protective container, having:
a first casing member having a body forming a storage space having:
the body extending from a first enclosed end to a first open end, the first enclosed end having at least a first side, a second side, and a third side, the third side being opposite the first open end and extending between the first side and the second side;
a bottom surface; and
a first protection device positioned within the storage space at the first enclosed end of the body and attached to at least the first side, the second side, and the third side of the first enclosed end and extending inwardly into the storage space from at least the first side, the second side, and the third side of the first enclosed end;
a plurality of support arms rigidly attached to the bottom surface of the storage space and configured to suspend an implement within the storage space of the container; and
a second casing member having a second enclosed end and a second open end and configured to removably attach to the first casing member at the first open end of the first casing and the second open end of the second casing member via tongue and grooves, the second casing member having:
a second protection device extending from the second enclosed end configured to hold the implement in a stationary position;
wherein the container when closed is sterilized to clean the implement.

US Pat. No. 10,426,843

DELTA-OPIOID RECEPTOR TARGETED AGENT FOR MOLECULAR IMAGING AND IMMUNOTHERAPY OF CANCER

1. A compound having Formula I,
wherein
n is an integer of from 1 to 50;
L1 and L2 are optional linking moieties of from 1 to 100 atoms in length; and
Ab is an antibody;
Tg* is H, a protecting group, or a detectable moiety; and
Dmt-Tic is represented by

where R1 and R2 are independently selected from H and CH3.

US Pat. No. 10,426,830

ALTERING THE IMMUNDOMINANCE HIERARCHY USING A DNA VACCINE EXPRESSING CONSERVED REGIONS

THE UNITED STATES OF AMER...

1. A method of inducing an immune response to an HIV protein, the method comprising administering:a first nucleic acid encoding a first conserved element polypeptide, wherein the conserved elements are from the HIV protein and the polypeptide comprises at least six conserved elements, each less than 50 amino acids in length, where the conserved elements are joined by linkers;
a second nucleic acid encoding a second conserved element polypeptide that comprises a variant of each of the at least six conserved elements contained in the first conserved element polypeptide, wherein each variant in the second conserved element polypeptide differs from the corresponding conserved element in the first conserved element polypeptide by at least 1, 2, or 3 amino acids; and
after administration of the first and the second nucleic acids, administering a nucleic acid encoding the full-length HIV protein, or substantially full-length HIV protein, wherein the nucleic acid encoding the full-length HIV protein or substantially full-length HIV protein is administered at least two weeks after the first and second nucleic acids encoding the conserved element polypeptides; and further, wherein the nucleic acid encoding the full-length HIV protein, or substantially full-length HIV protein, is administered as a plasmid that comprises an expression cassette comprising a nucleic acid sequence encoding the full-length HIV protein, or substantially full-length HIV protein, operably linked to a promoter.

US Pat. No. 10,426,784

IMIDAZODIAZEPINE COMPOUND

Astellas Pharma Inc., Ch...

14. A pharmaceutical composition, comprising a compound or a salt thereof according to claim 1 and a pharmaceutically acceptable excipient.

US Pat. No. 10,426,751

ALLOSTERIC ACTIVATORS FOR TREATMENT OF PHENYLKETONURIA

McMaster University, Ham...

1. A method of restoring phenylalanine hydroxylase activity in mammalian phenylalanine hydroxylase comprising exposing said phenylalanine hydroxylase to shikimic acid, a pharmaceutically acceptable salt of shikimic acid, a functionally equivalent analogue thereof selected from the group of:i) an analogue of shikimic acid having one or more additional substituents on the cyclohexene ring of shikimic acid, wherein the additional substituent is selected from the group consisting of hydroxyl, thio, —OR1, —NH2, NO2, —NHR1, —NR1R2, —SR1 and a C1-C6 alkyl group, C1-C6 alkoxy, and C1-C6 alkanol, wherein R1 and R2 are independently selected from the group consisting of C1-C6 alkyl, C1-C6 alkanol and C1-C6 alkoxy;
ii) an analogue in which one or more of the hydroxyl groups on the cyclohexene ring of shikimic acid is substituted with hydrogen, thio, C1-C6 alkyl, C1-C6 alkanol, C1-C6 alkoxy, —OR1, —NH2, NO2, —NHR1, —NR1R2, or —SR1; and
iii) an analogue in which the cyclohexene ring of shikimic acid is replaced with a cyclohexane ring;or combinations thereof.

US Pat. No. 10,426,739

ADHESIVE PATCH ASSEMBLY WITH OVERLAY LINER AND SYSTEM AND METHOD FOR MAKING SAME

3M Innovative Properties ...

15. A method of making an article comprising an adhesive patch assembly, the method comprising the steps of:providing a patch having a periphery, the patch including a backing, a skin-contact adhesive coupled to the backing, a drug, and a skin penetration enhancer;
providing a release liner including a first major surface and a second major surface opposite the first major surface, at least the first major surface configured to present release characteristics relative to the skin-contact adhesive of the patch, the release liner having a first portion and a second portion, wherein each of the first portion and the second portion are dimensioned to accommodate the patch, and wherein the release characteristics of the first major surface of the first portion of the release liner are coextensive with the first major surface of the second portion of the release liner;
including a slit into the second portion of the release liner, wherein the second portion further comprises two separate sections separated by the slit;
positioning the patch on the release liner, such that patch is located on the second portion of the release liner and the first portion of the release liner is free of the patch, wherein when the patch is located between the first portion and the second portion of the release liner the first and second portions having said release characteristics extend a distance beyond the periphery of the patch;
folding the release liner about a hinge located between the first portion and the second portion to locate the patch between the first portion and the second portion of the release liner and to form an adhesive patch assembly; and
packaging the adhesive patch assembly in a separate and distinct hermetically-sealed pouch.

US Pat. No. 10,426,737

LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS

Novartis AG, Basel (CH)

1. A compound of formula (I) or a pharmaceutically acceptable salt thereof:
wherein:
n is 0, 1, 2, 3 or 4;
p is 0, 1, 2, 3, 4, 5, 6, 7 or 8;
L1 is —O— or a bond;
L2 is —OC(O)— or —C(O)O—;
R1 is

v is 0, 1, 2, 3 or 4;
w is 0, 1, 2 or 3;
R and R? are each, independently, hydrogen or C1-8 alkyl;
R2 is selected from: (i) C6-20 alkyl optionally substituted with a hydroxyl, and (ii) C15-19 alkenyl;
R3 is selected from: C4-22 alkyl, C12-22 alkenyl,

US Pat. No. 10,426,735

MODIFIED ALGINATES FOR ANTI-FIBROTIC MATERIALS AND APPLICATIONS

Massachusetts Institute o...

1. A multiply modified alginate polymer having a structure according to Formula IIIwhereinX is oxygen, sulfur, or NR4;
R1, R6, R7, R8, and R9 are, independently, hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, substituted alkoxy, aroxy, substituted aroxy, alkylthio, substituted alkylthio, arylthio, substituted arylthio, carbonyl, substituted carbonyl, carboxyl, substituted carboxyl, amino, substituted amino, amido, substituted amido, sulfonyl, substituted sulfonyl, sulfonic acid, phosphoryl, substituted phosphoryl, phosphonyl, substituted phosphonyl, polyaryl, substituted polyaryl, C3-C20 cyclic, substituted C3-C20 cyclic, heterocyclic, substituted heterocyclic, amino acid, poly(ethylene glycol), peptide, or polypeptide group; wherein R1 and R6 are not hydrogen;whereinY1 and Y2 independently are hydrogen or —PO(OR5)2; or
Y2 is absent, and Y1, together with the two oxygen atoms to which Y1 and Y2 are attached form a cyclic structure as shown in Formula IV
whereinR2 and R3 are, independently, hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, substituted alkoxy, aroxy, substituted aroxy, alkylthio, substituted alkylthio, arylthio, substituted arylthio, carbonyl, substituted carbonyl, carboxyl, substituted carboxyl, amino, substituted amino, amido, substituted amido, polyaryl, substituted polyaryl, C3-C20 cyclic, substituted C3-C20 cyclic, heterocyclic, substituted heterocyclic, amino acid, poly(ethylene glycol), peptide, or polypeptide group; or
R2 and R3, together with the carbon atom to which they are attached, form a 3- to 8-membered unsubstituted or substituted carbocyclic or heterocyclic ring; and
R4 and R5 are, independently, hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, substituted alkoxy, aroxy, substituted aroxy, alkylthio, substituted alkylthio, arylthio, substituted arylthio, carbonyl, substituted carbonyl, carboxyl, substituted carboxyl, amino, substituted amino, amido, substituted amido, polyaryl, substituted polyaryl, C3-C20 cyclic, substituted C3-C20 cyclic, heterocyclic, substituted heterocyclic, amino acid, poly(ethylene glycol), peptide, or polypeptide group.

US Pat. No. 10,426,730

OXIDIZED CELLULOSE MICROSPHERES

Covidien LP, Mansfield, ...

1. A microsphere comprising:a first biodegradable polymer encapsulating at least one additional microsphere, the at least one additional microsphere including a second biodegradable polymer and at least one bioactive agent, wherein the first biodegradable polymer and the second biodegradable polymer are different and one of the first biodegradable polymer or the second biodegradable polymer is oxidized cellulose.

US Pat. No. 10,426,727

FLUOROPOLYMER EMULSIONS WITH BRANCHED SEMIFLUORINATED BLOCK COPOLYMER OR PHOSPHOLIPID SURFACTANT FOR THE DELIVERY OF HYDROPHOBIC DRUGS

Wisconsin Alumni Research...

2. An emulsion for delivery of a therapeutic agent, said emulsion comprising:an aqueous solution;
semi-fluorinated block copolymers; wherein each of said semi-fluorinated block copolymers independently comprises a hydrophilic block, a hydrophobic block and a fluorophilic block; wherein each of said semi-fluorinated block copolymers has a branched structure wherein said hydrophilic block comprises a first branch, said hydrophobic block comprises a second branch and said fluorophilic block comprises a third branch; and
said therapeutic agent comprising a hydrophobic compound;
said emulsion comprising a continuous phase and a dispersed phase, wherein said continuous phase comprises said aqueous solution and said dispersed phase comprises said semi-fluorinated block copolymers and said therapeutic agent;
wherein each of said semi-fluorinated block copolymers independently has the formula (FX9A) or (FX9B):

wherein q is an integer selected from the range of 10 to 300, o is an integer selected from the range of 5 to 20, and p is an integer selected from the range of 3 to 15.

US Pat. No. 10,426,703

VIAL ADAPTERS

UNL Holdings LLC, New Yo...

1. A method of transferring fluid from a vial comprising a closure to a safety syringe, said method including connecting a vial adapter to the closure of the vial and to the safety syringe, fitting lateral arms of the vial adapter to the closure so that the vial adapter is in fluid communication with said safety syringe and inserting a conduit tip of the vial adapter into the safety syringe, the conduit tip inhibiting travel of a plunger of the safety syringe towards a distal end of the safety syringe.

US Pat. No. 10,426,702

MIXING AND/OR TRANSFERRING DEVICE

1. A device for mixing or transferring a first substance and a second substance that are present, respectively, in a first and a second receptacle, comprising:a first adapter having a circumferential wall, and being configured to accept the first receptacle, and along which extends, and which, at least in sections, surrounds a first cannula body, and a first hollow-cylindrical section connected to the first cannula body,
a second adapter having a circumferential wall, and being configured to accept the second receptacle, and along which extends, and which, at least in sections, coaxially surrounds, a second cannula body, and a second hollow-cylindrical section connected to the second cannula body,
wherein, in an assembled state, the first hollow-cylindrical section inter-engages with the second hollow-cylindrical section, and the first adapter and the second adapter are screwably and detachedly connected,
wherein each of the first and the second adapters comprises a hollow-cylindrical outer body with an exterior circumferential wall, and a partition wall extending perpendicularly to a longitudinal axis of the outer body,
wherein, when the first and second adapters are assembled together, a section, which has an inner thread, of the outer circumferential wall of one of the first and the second adapters surrounds a section, which has an external thread, of the outer circumferential wall of the other of the first and the second adapters, with inter-engaging threaded sections,
wherein the hollow-cylindrical outer body of at least one of the first and second adapters comprises an insert, having a circumferential wall, that accepts the first or the second receptacle, and
wherein the circumferential wall of the insert extends, at least in sections of the interior surface of the outer circumferential wall, spaced-apart from the interior surface of the outer circumferential wall.

US Pat. No. 10,426,701

SINGLE USE CONNECTORS

MEDINSTILL DEVELOPMENT LL...

1. A connector comprising:a first piece;
a piercing member attached to the first piece; and
a second piece, the piercing member being slidingly receivable within the second piece;
wherein the piercing member and the second piece are movable relative to each other between a first position where the second piece closes a flow port and a second position where the flow port is open;
the first piece further including a locking mechanism adapted to lockingly connect the first piece to a device when engaged therewith, thereby preventing subsequent disconnection and disengagement of the first piece and the device.

US Pat. No. 10,426,700

SYRINGE ACCESSORY FOR TRANSFER OF AIR SENSITIVE MATERIALS

International Business Ma...

1. An apparatus for transferring fluid contained in a syringe, comprising:an airlock component having a cylindrical body, the cylindrical body having a first end, a second end, and a hollow tube disposed between the first end and the second end, wherein the hollow tube has an interior surface and an exterior surface;
an annular opening at the first end of the cylindrical body;
a gas inlet aperture from the exterior surface of the hollow tube to the interior surface of hollow tube;
a gas outlet aperture from the interior surface of the hollow tube to the exterior surface of the hollow tube;
an inwardly-facing airtight material coupled to the interior surface of the hollow tube; and
a septum coupled to the second end of the cylindrical body.

US Pat. No. 10,426,697

COMPACT ELECTRO-MECHANICAL CHEST COMPRESSION DRIVE

Koninklijke Philips N.V.,...

1. A cardio-pulmonary compression device, comprising:a motor having a rotating portion;
a ball nut mounted on the rotating portion and configured to rotate with the rotating portion;
a ball screw being received in the ball nut such that rotation on the ball nut advances and/or retracts the ball screw in accordance with a direction of the motor;
a pad assembly coupled to an end portion of the ball screw such that longitudinal motion of the ball screw imparts a compression cycle to a patient.

US Pat. No. 10,426,695

SYSTEM AND METHOD FOR CARDIOPULMONARY RESUSCITATION

COVIDIEN LP, Mansfield, ...

1. A method for determining an efficacy of cardiopulmonary resuscitation (CPR), the method comprising, using a processor configured to determine the efficacy of CPR, wherein the processor is associated with a patient monitor, an oximetry sensor, and an electrocardiogram (ECG) sensor, and wherein determining the efficacy of CPR comprises:receiving, at the processor, a plethysmography signal from the oximetry sensor;
receiving, at the processor, an ECG signal from the ECG sensor;
determining a first indicator related to the efficacy of CPR based on the plethysmography signal, using the processor;
determining a second indicator related to the efficacy of CPR based on the ECG signal, using the processor;
combining the first indicator and the second indicator to determine a combination metric indicative of the efficacy of CPR, using the processor; and
adjusting parameters controlling one or both of a rate or depth of compressions applied by a CPR device based on the combination metric.

US Pat. No. 10,426,617

LOW PROFILE VALVE LOCKING MECHANISM AND COMMISSURE ASSEMBLY

BOSTON SCIENTIFIC SCIMED,...

1. A replacement heart valve locking mechanism, comprising:a buckle member fixedly attached to a tubular anchor member;
a post member axially translatable relative to the buckle member; and
an actuator member releasably connected to the post member at an attachment point;
wherein the post member includes a latch portion configured to engage a catch formed in the buckle member such that movement of the post member distally relative to the buckle member is prevented;
wherein the attachment point is disposed proximal of the latch portion;
wherein the post member includes a cantilevered leg extending proximally from a distal end of the post member and radially inward from the tubular anchor member;
wherein distal movement of the actuator member relative to the post member is configured to disengage the latch portion from the catch.

US Pat. No. 10,426,612

MEDICAL DEVICE DELIVERY SYSTEMS AND METHODS

Medtronic Vascular Galway...

1. A system for replacing a native heart valve of a patient, comprising:a prosthetic heart valve comprising a self-expanding frame and a valve assembly coupled to the self-expanding frame, the prosthetic heart valve comprising a first end portion, an intermediate portion, and a second end portion; and
a delivery system for deploying the prosthetic heart valve, the delivery system comprising:
a first attachment member configured to selectively couple to and radially constrain the first end portion of the prosthetic heart valve; and
a second attachment member configured to selectively couple to and radially constrain the second end portion of the prosthetic heart valve,
wherein the first attachment member is configured to move relative to the second attachment member such that the first attachment member applies a first tensile force to the first end portion of the prosthetic heart valve in a first direction and the second attachment member applies a second tensile force to the second end portion of the prosthetic heart valve in a second direction substantially opposite from the first direction, and
wherein the first attachment member and the second attachment member are configured to selectively decouple from the first end portion and the second end portion, respectively, to release the prosthetic heart valve from the delivery system, thereby enabling the prosthetic heart valve to self-expand.

US Pat. No. 10,426,611

LOW PROFILE TRANSCATHETER HEART VALVE

Edwards Lifesciences Corp...

1. An assembly comprising:a delivery catheter comprising a balloon; and
an implantable prosthetic heart valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, the prosthetic heart valve comprising:
a radially expandable annular frame having an inflow end portion defining an inflow end of the frame that is configured to receive antegrade blood flow into the prosthetic heart valve when implanted within a patient's body in the expanded configuration, and the frame also having an outflow end portion defining an outflow end of the frame opposite the inflow end of the frame;
wherein the frame comprises at least first and second circumferentially extending rows of angled struts arranged end-to-end in a zig-zag pattern and a plurality of axially extending struts interconnecting the first and second rows of angled struts; and
wherein each of the axially extending struts joins to a U-shaped crown structure joining adjacent ends of struts of the first row of angled struts and joins to a U-shaped crown structure joining adjacent ends of struts of the second row of angled struts, wherein the first and second rows of angled struts and axially extending struts form a circumferentially extending row of six-sided cells of the frame;
wherein the prosthetic valve can be radially crimped to the collapsed configuration around the balloon for delivery into a patient's body and radially expanded to the expanded configuration with the balloon inside the patient's body.

US Pat. No. 10,426,609

FIBER REINFORCED PROSTHETIC HEART VALVE HAVING UNDULATING FIBERS

Boston Scientific Scimed,...

1. A prosthetic heart valve comprising:a plurality of leaflets comprising:
a composite material comprising a first plurality of polymeric fibers embedded in a polymer matrix, each fiber of the first plurality of polymeric fibers having a first common extending direction and a plurality of regularly spaced repeating undulations, wherein the plurality of regularly spaced repeating undulations of the first plurality of polymeric fibers is adapted to provide the composite material with multi-stage elastic properties; and
wherein the plurality of regularly spaced repeating undulations of the first plurality of polymeric fibers has crests that extend in a direction orthogonal to the first common extending direction;
wherein each leaflet comprises a first sleeve portion, a second sleeve portion, and a body portion disposed between the first and the second sleeve portions; and
wherein at least a portion of the first plurality of polymeric fibers extend along a linear path along the first common extending direction comprising a circumferential direction between the first sleeve portion and the second sleeve portion.

US Pat. No. 10,426,608

REPOSITIONABLE HEART VALVE

BOSTON SCIENTIFIC SCIMED,...

1. A replacement heart valve assembly comprising:an expandable anchor having a delivery configuration and a fully deployed configuration, the expandable anchor comprising a skirt region, a lip region, and a groove region therebetween;
in the delivery configuration, the expandable anchor having a first diameter and a first length and in the fully deployed configuration having a second diameter and a second length, wherein the first length is greater than the second length and the second diameter is greater than the first diameter;
a replacement valve disposed within the expandable anchor, the replacement valve including posts and hoop regions, the posts and hoop regions having a collapsed delivery configuration and an expanded deployed configuration in which the hoop regions are adapted to engage the groove region of the expandable anchor in the fully deployed configuration thereof;
the lip region of the expandable anchor is configured and adapted to expand radially outward relative to the groove region while transitioning from the delivery configuration to the fully deployed configuration to engage native valve leaflets and to provide positive registration and ensure accurate placement of the expandable anchor relative to a valve annulus during deployment.

US Pat. No. 10,426,607

APPARATUS FOR REPLACING A NATIVE HEART VALVE AND METHOD OF MAKING THE SAME

BOSTON SCIENTIFIC SCIMED,...

1. An apparatus for replacing a native heart valve comprising:an expandable anchor having a central longitudinal axis;
a replacement heart valve attached to the expandable anchor; and
a plurality of rivets;
the expandable anchor comprising a woven braid structure surrounding at least a portion of the replacement heart valve, the woven braid structure having a plurality of braid intersections, each braid intersection having a first wire segment and a second wire segment overlapping the first wire segment,
wherein the woven braid structure defines an inflow end and an outflow end;
each of the plurality of rivets extending through the first wire segment and the second wire segment at one of the plurality of braid intersections along a radial axis normal to the central longitudinal axis,
wherein at least some of the plurality of braid intersections of the woven braid structure between the inflow end and the outflow end of the woven braid structure are free of the plurality of rivets;
wherein the first wire segment is hingeable with respect to the second wire segment along the radial axis,
a plurality of buckles attached to the expandable anchor; and
a plurality of posts insertable into the plurality of buckles;
wherein the plurality of rivets is disposed between the plurality of posts at consecutive braid intersections along the inflow end of the woven braid structure.

US Pat. No. 10,426,602

INTRAOCULAR LENS (IOL) INJECTOR AND METHOD OF USE THEREOF

AST Products, Inc., Bill...

1. An intraocular lens (IOL) injector comprising:a) an injector body elongated along a longitudinal axis, the injector body having a lumen disposed along the longitudinal axis;
b) a lens cartridge in operable connection with the injector body, the lens cartridge having a lumen configured to receive an IOL and a positioning mechanism for folding and aligning the IOL in the lens cartridge lumen, wherein the lens cartridge lumen is coextensive with the injector body lumen;
c) an injector tip in operable connection with the lens cartridge, the injector tip having a lumen disposed along the longitudinal axis and terminating in a distal opening, wherein the injector tip lumen is coextensive with the injector body lumen;
d) a plunger having an elongated shaft, the elongated shaft being slidably disposed within the injector body lumen from an undeployed position to a deployed position, wherein the plunger is configured to contact the IOL in the lens cartridge lumen and push the IOL along the longitudinal axis through the injector tip lumen and out of the distal opening when the plunger is transitioned to the deployed position; and
e) a sleeve in operable connection with the lens cartridge, wherein the lens cartridge is configured to fold the IOL and align the IOL within the lens cartridge lumen via the positioning mechanism upon moving the sleeve over the lens cartridge from a first position to a second position, the sleeve covering at least a portion of the lens cartridge in the second position, wherein the positioning mechanism comprises a first cartridge portion having a surface adapted to contact an internal surface of the sleeve and urge the first cartridge portion toward a second cartridge portion when the sleeve is moved from the first position to the second position.

US Pat. No. 10,426,600

ACCOMMODATING INTRAOCULAR LENS AND METHODS OF USE

University of Houston, H...

1. An accommodating intraocular lens (IOL) comprising:a flexible retainer plate consisting of a material annular region surrounding a central aperture having a diameter,
wherein the annular region has an inner surface defining the diameter of the central aperture,
characterized by a flexibility that is sufficient to allow a continuous accommodating movement of the IOL; and
an optical element consisting of a single optical lens having an anterior surface and a posterior surface, disposed fully within the aperture, and at least one of one or more flanges on the anterior surface to prevent posterior displacement and one or more flanges on the posterior surface to prevent anterior displacement.

US Pat. No. 10,426,599

MULTIFOCAL LENS HAVING REDUCED CHROMATIC ABERRATIONS

Novartis AG, Basel (CH)

1. A multifocal ophthalmic lens comprising:an anterior surface;
a posterior surface; and
at least one diffractive structure including a plurality of echelettes having at least three different step heights of at least one wavelength and not more than two wavelengths in optical path length, the at least one diffractive structure residing on at least one of the anterior surface and the posterior surface, the at least one diffractive structure providing:
a first diffractive order for a first focus corresponding to a first focal length;
a second diffractive order for a second focus corresponding to a second focal length, the second focal length being different from the first focal length;
a third diffractive order for a third focus corresponding to a third focal length, the third focal length being different from the first focal length and the second focal length;
a fourth diffractive order for a fourth focus corresponding to a fourth focal length, the fourth focal length being different from the first focal length and the second focal length and the third focal length; and
wherein the diffractive structure excludes a 0th diffractive order.

US Pat. No. 10,426,598

IMAGE PROCESSING METHOD AND SYSTEM FOR IRREGULAR OUTPUT PATTERNS

Monash University, Clayt...

1. A visual image processing system comprising:a sensor input configured to receive spatial field information from an associated spatial field sensor;
a data store containing a sensor map data structure which comprises a set of predefined regions within a spatial field corresponding with the information received via the sensor input, wherein each predefined region is associated in the data structure with one or more of a set of stimuli applicable to a biological visual system, each stimulus corresponding to a visual percept;
a visual image processor configured to process spatial field information associated with each region to generate stimulus control information, and to apply the stimulus control information to select, from within the sensor map data structure, stimuli from the set of stimuli for application to the biological visual system;
a signal generator configured to receive the selected stimuli from the visual image processor, and to generate corresponding output stimulus signals for application to the biological visual system; and
an auxiliary image source configured to provide spatial field information in place of information received from the spatial field sensor, wherein spatial field information provided by the auxiliary image source comprises one or more predetermined test images; and
a visualisation system configured to display a simulated image representative of the sensory experience of a subject associated with the biological visual system;
wherein the data store contains a percept map data structure comprising information relating to the location and appearance of visual percepts experienced by the subject in response to stimuli within the set of stimuli.

US Pat. No. 10,426,597

SOFT TISSUE REBALANCING DEVICE AND METHOD

1. A soft tissue rebalancing method to rebalance a phalanx comprising the steps of:forming a mesh body portion having a ligament mesh portion and a braided mesh portion;
positioning the mesh body portion on a phalanx;
connecting the ligament mesh portion to a driver tool;
tensioning the ligament mesh portion to increase the tension of the mesh body portion on the phalanx;
performing transverse plane correction on the phalanx.

US Pat. No. 10,426,591

EMBOLIC DEFLECTION DEVICE

Edwards Lifesciences AG, ...

1. A method of reducing the risk of emboli entering the cerebral circulation as a consequence of an index procedure in the heart or the aorta, comprising the steps of:placing a wire through a first side branch vessel and into the aortic arch;
advancing an elongated introducer sheath over the wire and along the first side branch vessel until a distal end of the sheath is positioned in the aortic arch, wherein the elongated introducer sheath houses an expandable emboli deflection device attached to a distal end of an elongate shaft, the emboli deflection device having an elongated periphery in plan view when expanded, the periphery defined by a Nitinol skeleton in a modified rectangle with straight longitudinal sides terminating in opposite rounded ends, the periphery having a concave depth profile with a concave side facing toward the shaft, the emboli deflection device having a porous material stretched over the skeleton, the material having pores to allow the flow of blood but deflect or trap emboli;
retracting the sheath to expose and permit the emboli deflection device to expand;
manipulating the emboli deflection device such that the concave side covers the ostia of each of the first side branch vessel and a second side branch vessel, wherein manipulating the deflection device comprises pulling the shaft to create a seal between the periphery of the emboli deflection device and a wall of the aortic arch around the ostia of the first and second side branch vessels;
wherein the emboli deflection device permits blood flow from the main vessel into each of the first and second side branch vessels, but deflects emboli from entering the first and second side branch vessels;
performing an index procedure in the heart selected from the group consisting of a balloon aortic or mitral valvuloplasty, a mitral or aortic valve replacement, and a coronary angioplasty; and
retracting the emboli deflection device into the sheath and withdrawing the sheath from the body.

US Pat. No. 10,426,590

FILTERS WITH ECHOGENIC CHARACTERISTICS

VOLCANO CORPORATION, San...

1. A filter comprising:a hub; and
a plurality of legs or wires or segments extending from the hub; wherein the plurality of legs or wires or segments comprise a first section having a first pattern of voids formed therein to provide an enhanced echogenic characteristic of the first section and a second section having a second pattern of voids formed therein to provide an enhanced echogenic characteristic of the second section, wherein the first pattern of voids is different than the second pattern of voids.

US Pat. No. 10,426,589

SYSTEM AND METHOD FOR DELIVERING A LEFT ATRIAL APPENDAGE CONTAINMENT DEVICE

BOSTON SCIENTIFIC SCIMED,...

1. A system for deploying a medical implant, comprising:a delivery catheter having a lumen extending therethrough;
an elongate shaft slidably disposed within the lumen of the delivery catheter; and
an expandable implant including a proximal tubular portion and a distal tubular portion discontinuous with the proximal tubular portion;
wherein the distal tubular portion extends at least partially within an interior of the implant,wherein the distal tubular portion includes a slot forming an opening extending from an interior surface of the distal tubular portion through a wall thereof to an exterior surface of the distal tubular portion.

US Pat. No. 10,426,586

SACROCOLPOPEXY SUPPORT

1. A sacrocolpopexy support comprising:a head section extending from a first end portion to a second end portion;
a leg section having a first leg portion placed on and in longitudinal alignment with a second leg portion;
a first connector securing the leg section to the second end portion of the head section; and
a second connector securing the first leg portion to the second leg portion to form a closed joint that defines a space between the first leg portion and the second leg portion;
wherein an end of the second end portion of the head section terminates at a location exterior to the closed joint outside of the space between the first leg portion and the second leg portion.

US Pat. No. 10,426,585

FECAL INCONTINENCE TREATMENT DEVICE AND METHOD

Boston Scientific Scimed,...

1. An implant device for treating fecal incontinence in a patient, comprising:a restriction member having a first end portion, a second end portion, and an intermediate restriction portion adapted to wrap around a portion of an anal sphincter of the patient, the intermediate restriction portion including a first portion and a second portion, the first portion including interwoven filaments and extending from the first end portion to the second end portion, the second portion including a plurality of non-woven struts and extending from the first end portion to the second end portion, the plurality of non-woven struts being interwoven with the interwoven filaments, the plurality of non-woven struts including voids configured to increase tissue in-growth, the voids being disposed between the plurality of non-woven struts;
at least two first connector elements provided at the first end portion; and
at least two second connector elements provided at the second end portion and adapted to connect with the at least two first connector elements to retain the restriction member around the anal sphincter of the patient to promote continence.

US Pat. No. 10,426,584

METHOD OF TREATING URINARY INCONTINENCE BY IMPLANTING A RESERVOIR AROUND A URETHRA OF THE USER

1. A method of treating urinary incontinence, the method comprising:implanting one and only one reservoir in a body of a user by placing the reservoir around a urethra of the user, where the reservoir includes a first compartment and a storage compartment having a pathway communicating with the first compartment;
placing a liquid in the reservoir;
implanting a pump in the body of the user, with the pump communicating with the reservoir;
operating the pump and moving the liquid from the first compartment to the storage compartment thus relieving a constriction of the urethra and allowing the user to pass urine through the urethra; and
configuring the reservoir to move the liquid from the storage compartment through the pathway to the first compartment and constricting the urethra of the user in providing the user with urinary continence.

US Pat. No. 10,426,583

HIGH TRANSLUCENT COLORED DENTAL ZIRCONIA BLANK

20. A colored zirconia sintered body comprising:a) a sintered body comprising zirconia containing between 6.0 wt % to 20 wt % of yttria (Y2O3);
b) the sintered body having multiple different colored layers;
c) at least one of the colored layers having a total light transmittance of at least 50% to light with a wavelength at a point between 600 nm and 800 nm;
d) a difference in total light transmittance between at least two adjacent vertical layers being less than 2% to light with wavelength of 600 nm, with a layer on one side having lower total light transmittance than a layer on the other side, with a translucency increasing from one side to the other side.

US Pat. No. 10,426,576

METHOD FOR DEBONDING OF ORTHODONTIC METAL BRACKETS WITH EUGENOL EMULGEL

King Abdulaziz University...

1. A method for removing an object bound to a tooth or teeth via a dental cement or dental resin, comprising:contacting the dental cement or dental resin with a gel comprising eugenol for a time sufficient to reduce Vickers hardness of the dental cement or dental resin or for a time sufficient to decrease debonding force needed to remove a metal bracket, dental appliance or dental prosthetic from the tooth or teeth, and
removing the metal bracket, dental appliance or dental prosthetic from the tooth or teeth.

US Pat. No. 10,426,574

COMPUTER SYSTEM-AIDED DESIGN OF DENTAL APPLIANCES

3M INNOVATIVE PROPERTIES ...

1. A method comprising:receiving, with a computer system, a digital representation of a three-dimensional (3D) tooth structure of a patient, the tooth structure providing initial positions of one or more teeth of the patient;
determining, with the computer system, dimensions and shapes of a removable dental appliance for the patient, the dimensions and shapes of the removable dental appliance being configured to reposition the one or more teeth of the patient from their initial positions to adjusted positions when the removable dental appliance is worn by the patient; and
transmitting, with the computer system, a representation of the removable dental appliance to a computer-aided manufacturing system,
wherein the removable dental appliance comprises an appliance body configured to surround two or more teeth of the patient, wherein the appliance body having an active band and at least one anchor includes:
a facial portion configured to register with facial sides of the surrounded teeth; and
a lingual portion configured to register with lingual sides of the surrounded teeth,
wherein the appliance body is configured such that occlusal surfaces of the surrounded teeth of the patient are exposed when the removable dental appliance is worn by the patient,
wherein the facial and lingual portions form an active band of the removable dental appliance, and wherein the appliance further comprises one or more struts connected to the active band, wherein the removable dental appliance further comprises anchors extending from each side of the appliance body, and wherein the struts couple the active band to the anchors.

US Pat. No. 10,426,570

POSITIONING APPARATUS FOR BIOMEDICAL USE

CONMED CORPORATION, Utic...

1. A medical positioning apparatus for positioning and holding an object, comprising:a telescopic member extending between a first end and a second end and having an adjustable length;
a support member for receiving the object;
a base member securable to a base;
a first joint mechanism movably securing the support member to the first end of the telescopic member;
a second joint mechanism including a housing with a top portion directly rotationally connected to the second end of the telescopic member, a bottom portion opposite the top portion, and at least one side portion directly rotationally connected to the base member and movably securing the base member to the second end of the telescopic member, the first and second joint mechanisms each having at least two rotational degrees of freedom;
a locking device operatively connected to the first and second joint mechanisms and the telescopic member, the locking device operable between a locked position in which the support member, the base member, and the telescopic member are lockingly interconnected together and the length of the telescopic member is fixed, and a released position in which the support and base members are free to pivotally move with respect to the telescopic member and the length of the telescopic member is adjustable, the locking device being passively biased in the locked position; and
a lock activation device to unlock the locking device biased in the locked position in order to adjust the length of the telescopic member and a relative position of the support member, the base member, and the telescopic member.

US Pat. No. 10,426,566

METHODS AND SYSTEMS FOR PULSED ILLUMINATION

Novartis AG, Basel (CH)

1. A vitreoretinal surgical system for performing an ocular treatment procedure, comprising:an illumination instrument sized and structurally configured to illuminate tissue at a surgical site during an ocular treatment procedure;
a light source arranged to provide illumination to the illumination instrument for emission from the illumination instrument toward the surgical site; and
a controller in communication with the light source and configured to activate the light source in a manner providing illumination pulses at a frequency above a flickering perception in humans;
wherein the system is configured to receive a desired overall light intensity level from a user and wherein the controller is configured to determine the frequency, pulse width, and pulse intensity to provide the desired overall light intensity level.

US Pat. No. 10,426,564

APPARATUS AND METHOD FOR APPLYING LIGHT IN OCULAR AND PERIOCULAR AREAS

Lumenis Ltd., Yokneam (I...

1. A method of protecting ocular tissue during application of light energy, the method comprising:providing a handpiece having a light energy device, the handpiece having a tip having a shielding extension configured to be inserted posterior to an eyelid;
inserting the shielding extension behind the eyelid prior to applying light energy to an anterior surface of the eyelid;
applying light energy from the light energy device to an anterior surface of the eyelid;
wherein the light energy device is an LED or a laser; and
wherein the shielding extension is comprised of a thermally insulative material such that energy not absorbed by a target tissue is prevented from reaching ocular tissue located posterior to the eyelid.

US Pat. No. 10,426,555

MEDICAL INSTRUMENT WITH SENSOR FOR USE IN A SYSTEM AND METHOD FOR ELECTROMAGNETIC NAVIGATION

COVIDIEN LP, Mansfield, ...

1. A medical instrument, comprising:a base non-conductive layer on a distal portion of the medical instrument;
a sensor printed on the base non-conductive layer, the sensor including a first conductive coil, a second conductive coil, and a non-conductive layer disposed between the first conductive coil and the second conductive coil;
a proximal conductive layer printed circumferentially around a proximal portion of the medical instrument;
a proximal non-conductive layer printed on the proximal conductive layer; and
at least one pair of contacts electrically connected to at least one of the first conductive coil or the second conductive coil of the sensor and coupled to the proximal conductive layer, the proximal conductive layer connectable to a measurement device configured to sense an induced electrical signal in the sensor based on a magnetic flux change of an electromagnetic field,
wherein a location of the medical instrument in a coordinate system of the electromagnetic field is identified based on the induced electrical signal in the sensor.

US Pat. No. 10,426,552

REDUCTION METHODS FOR ALIGNING BONE SEGMENTS USING CUSTOMIZED JIGS

1. A reduction method for aligning a first bone segment and a second bone segment comprising:surgically attaching: (i) a first interaction implant to the first bone segment; and (ii) a second interaction implant to the second bone segment;
imaging the first and second bone segments to create a model;
processing the model to find an optimal bone alignment;
generating, based on the optimal bone alignment and with a three-dimensional printer, a custom jig, wherein the custom jig includes a global jig element, a first local jig element, and a second local jig element;
attaching the first local jig element to the first interaction implant;
attaching the second local jig element to the second interaction implants; and
engaging, after attaching the custom jig to the first and second interaction implants, the first and second local jig elements with the global jig element;
wherein the first and second bone segments are translated as the first and second local jig elements are engaged with the global jig element; and
wherein the first bone segment and second bone segment are properly aligned in the optimal bone alignment.

US Pat. No. 10,426,549

METHODS FOR PATIENT-SPECIFIC SHOULDER ARTHROPLASTY

Biomet Manufacturing, LLC...

1. A method of positioning a virtual guide on a virtual model of a patient's scapula for installing a glenoid implant, the method comprising:creating the virtual model of a patient's scapula using software run by a processor, the virtual model created from an anatomical image of the patient's scapula;
identifying at least a first point on an anterior rim of a glenoid fossa and a second point on a posterior rim of the glenoid fossa of the virtual model; and
positioning the virtual guide on the virtual model of the glenoid fossa as a function of the first point on the anterior rim and the second point on the posterior rim.

US Pat. No. 10,426,547

SURGICAL LASER SYSTEM AND LASER FIBER

Boston Scientific Scimed,...

1. An optical device, comprising:a controller coupled to a first treatment laser source and a first aiming laser source, wherein the controller is configured to:
in response to a request to discharge the first treatment laser source from a non-discharged state, discharge the first aiming laser source from a non-discharged state to deliver a first aiming beam in a first direction, and discharge the first treatment laser source from the non-discharged state to deliver a first laser energy in the first direction, wherein the first laser energy has a first wavelength configured to perform a first treatment, and the first aiming beam does not cause tissue damage.

US Pat. No. 10,426,522

RECEIVING PART FOR RECEIVING A ROD FOR COUPLING THE ROD TO A BONE ANCHORING ELEMENT

1. A receiving part for receiving a rod for coupling the rod to a bone anchoring element, the receiving part comprising:a receiving part body having a first end, a second end below the first end, a substantially U-shaped recess at the first end forming a channel for receiving the rod, an accommodation space for accommodating a head of the bone anchoring element, and an opening at the second end for inserting the head into the accommodation space; and
a pressure element configured to be arranged at least partially in the accommodation space, the pressure element comprising a first section configured to contact the rod when the pressure element is in the receiving part body, and a second section axially connected to the first section and having an expandable portion configured to accommodate and clamp the head;
wherein the pressure element is insertable upwards through the opening at the second end of the receiving part body into the accommodation space; and
wherein when the pressure element is in the receiving part body, the pressure element is configured to assume a pre-locking position wherein an abutment at an inner wall of the receiving part body holds the pressure element against movement towards the first end of the receiving part body, while the inner wall of the receiving part body further restricts expansion of the expandable portion to prevent removal of an inserted head of the bone anchoring element from the receiving part.

US Pat. No. 10,426,516

TROCAR SEAL SYSTEM

Covidien LP, Mansfield, ...

1. A surgical access apparatus, which comprises:an access member defining a longitudinal axis, the access member having a longitudinal opening to permit passage of a surgical object, the access member being dimensioned for insertion within body tissue to permit access to an underlying site, and defining proximal and distal ends, the access member including a housing segment and an elongated segment, the housing segment having internal walls that include a proximal wall surface and a lateral wall, the internal walls of the housing segment defining an object seal channel; and
an object seal mounted within the object seal channel of the housing segment, the object seal configured to move during manipulation of the surgical object, the object seal including:
a generally annular seal support; and
a seal member secured to the generally annular seal support, the seal member comprising:
a resilient material and a fabric material;
an inner seal segment defining an inner passage configured to permit passage of the surgical object in substantial sealed relation therewith;
an outer flange segment disposed radially outward of the generally annular seal support, the outer flange segment bending outwardly and having a radially outer-most free end disposed flat against only the proximal wall surface of the housing segment, the radially outer-most free end of the outer flange segment detached from the lateral wall of the housing segment; and
wherein the seal member defines at least one aperture adjacent the outer flange segment, the at least one aperture adapted for at least partial reception of the generally annular seal support.

US Pat. No. 10,426,515

TRANSSEPTAL ACCESS DEVICE AND METHODS

THE REGENTS OF THE UNIVER...

1. A method of performing a procedure in the left heart of a subject comprising the steps of:inserting a puncture needle and transseptal access sheath into the vasculature of the subject;
advancing the puncture needle and transseptal access sheath into the right ventricle;
guiding the puncture needle and transseptal access sheath to the inter-ventricular septum;
advancing the puncture needle through the inter-ventricular septum into the left ventricle;
advancing at least a portion of the transseptal access sheath over the puncture needle into the left ventricle;
removing the puncture needle such that the transseptal access sheath remains positioned across the inter-ventricular septum, thereby forming a passageway from the right ventricle to the left ventricle through the transseptal access sheath;
advancing an instrument through the transseptal access sheath into the left ventricle;
performing a procedure in the left ventricle with the instrument while the transseptal access sheath is maintained across the inter-ventricular septum; and
removing the instrument through the transseptal access sheath.

US Pat. No. 10,426,509

MEDIAN LOBE DESTRUCTION APPARATUS AND METHOD

NeoTract, Inc., Pleasant...

1. A system for treating a median prostatic lobe of a patient, comprising:a handle configured to remain outside the patient;
an actuator operable by a user after the system has been placed partially within a urethra;
an introducer coupled to the handle and configured to be placed within the urethra of the patient;
a needle advanceable from the introducer by operation of the actuator to move through a curved trajectory to align with the handle, the needle being extendable from a portion of the system placed within the urethra and the needle being sized and configured to form an initial penetration track within the median prostatic lobe, wherein the needle exits from a side of the introducer;
an elongate member including a cutting blade with a hooked distal end, the elongate member being advanceable within and beyond a distal end of the needle while the distal end of the needle is within the median prostatic lobe;
and an elongate cylindrical implant deliverable through the introducer to be implanted in a passageway through the median prostatic lobe;
wherein the system is configured to treat the median prostatic lobe by dissecting and removing a portion of the median prostatic lobe.

US Pat. No. 10,426,508

CORDLESS HAND-HELD ULTRASONIC CAUTERY DEVICE

COVIDIEN AG, (CH)

1. An ultrasonic surgical assembly, comprising:a surgical handle including a first handle body portion defining an aseptically sealable battery-holding compartment and a second handle body portion connected to the first handle body portion;
a waveguide supported by and extending distally from the second handle body portion;
a cordless ultrasonic generator supported by the second handle body portion, the cordless ultrasonic generator including a driving-wave generation circuit and a shell housing the driving-wave generation circuit;
a cordless ultrasonic transducer supported by the second handle body portion, the cordless ultrasonic transducer coupled to the driving-wave generation circuit and having an output couple connected to the waveguide; and
a battery, wherein the first handle body portion is configured to removably hold the battery within the aseptically sealable battery-holding compartment, and wherein the surgical handle is configured to electrically connect the battery with the cordless ultrasonic generator when the battery is disposed within the battery-holding compartment.

US Pat. No. 10,426,507

ULTRASONIC SURGICAL INSTRUMENTS

Ethicon LLC, Guaynabo, P...

1. A surgical instrument, comprising:a transducer configured to generate an acoustic standing wave of vibratory motion along a longitudinal axis, wherein the transducer comprises a piezoelectric stack positioned along the longitudinal axis, wherein the transducer is configured to resonate at a predetermined vibrational frequency, wherein a wavelength of the acoustic standing wave corresponds to the predetermined vibrational frequency, and wherein a length of the transducer is less than ½ of the wavelength of the acoustic standing wave; and
an end effector acoustically coupled to and extending distally from the transducer along the longitudinal axis;
wherein a sum of the length of the transducer and a length of the end effector is an integer multiple of ½ of the wavelength of the acoustic standing wave.

US Pat. No. 10,426,506

ULTRASONIC SURGICAL INSTRUMENT WITH MULTI-GRIP ACTIVATION AND POWER SELECTION

Ethicon LLC, Guaynabo, P...

1. An ultrasonic instrument for use during a surgical procedure, comprising:(a) a body defining a longitudinal axis and configured to receive an ultrasonic transducer for selectively generating an ultrasonic oscillation at a first predetermined power level and an ultrasonic oscillation at a second predetermined power level;
(b) a shaft assembly projecting from the body, the shaft assembly including an acoustic waveguide configured to communicate the selected first or second predetermined power level therealong;
(c) an ultrasonic blade connected to the acoustic waveguide such that the acoustic waveguide communicates the selected first or second predetermined power level to the ultrasonic blade; and
(d) an actuation assembly connected to the body and configured to selectively activate the ultrasonic blade, the actuation assembly comprising:
(i) a selector collar generally surrounding the body and being selectively moveable relative to the body between a first selector collar position, a second selector collar position, and a third selector collar position, the selector collar configured to select from the first predetermined power level and the second predetermined power level and
(ii) a plurality of activation buttons operable to initiate activation of the ultrasonic blade at the predetermined power level as selected by the selector collar,
(e) a switch assembly, including:
(i) an electrical contact selector switch operatively connected to the selector collar and movable to an open selector position to thereby be configured to electrically disconnect from a transducer circuit, and
(ii) at least one electrical contact activation switch operatively connected to at least one of the plurality of activation buttons and movable to a closed activation position to thereby be configured to electrically connect to the transducer circuit,
wherein the electrical contact selector switch in the open selector position is an off mode that inhibits oscillation of the ultrasonic blade despite operation of the at least one activation button directing the at least one electrical contact activation switch to the closed activation position.

US Pat. No. 10,426,503

SYSTEM AND METHOD FOR PERFORMING SURGICAL PROCEDURES WITH A REUSABLE INSTRUMENT MODULE

Covidien LP, Mansfield, ...

1. A handle assembly of a surgical instrument, the handle assembly comprising:an outer housing shell defining a cavity;
an instrument module selectively insertable into the cavity of the outer housing shell and including:
an inner housing shell defining a cavity therein; and
a motor disposed within the cavity of the inner housing shell;
wherein the inner housing shell and the outer housing shell are configured such that a driving force of the motor is communicated through each of the inner housing shell and the outer housing shell when the motor is contained within the inner housing shell and when the instrument module is contained within the outer housing shell.

US Pat. No. 10,426,499

METHOD AND APPARATUS TO DETECT THE FRAGMENTATION OF KIDNEY STONES BY MEASURING ACOUSTIC SCATTER

University of Washington,...

1. A computer-implemented method for determining fragmentation of a kidney stone, comprising:generating a first acoustic wave and a second acoustic wave, wherein the first acoustic wave and the second acoustic wave are directed to the kidney stone;
receiving a first resonant wave from a pre-fragmented kidney stone that is a first particle having a first size;
receiving a second resonant wave from a post-treated kidney stone;
determining that a second particle has a second size, wherein the first resonant wave is induced by internal stress vibrations in the pre-fragmented kidney stone in response to the first acoustic wave and the second resonant wave is induced by internal stress vibrations in the post-treated kidney stone in response to the second acoustic wave;
determining a first frequency of the first resonant wave and a second frequency of the second resonant wave, wherein the first frequency and the second frequency scale inversely with the first size and the second size;
calculating the first size of the first particle from the first frequency;
calculating the second size of the second particle from the second frequency; and
based on calculating the first size and the second size, determining one of (a) that the kidney stone is fragmented when the second size is smaller than the first size and (b) that the kidney stone is not fragmented when the second size is the same as the first size.

US Pat. No. 10,426,496

METHOD FOR SURGICALLY REMOVING A TUMOR FROM A WOMAN'S BREAST

1. A method for surgically removing a tumor from a woman's breast, comprising:inserting a single optical trocar having working channels and a transparent tip through a skin incision located at a breast;
visually guiding the transparent tip of the single optical trocar as the single optical trocar advances through breast tissue with visualization through the transparent tip of the single optical trocar until the transparent tip of the single optical trocar is placed adjacent to the tumor;
insufflating gas via one of the working channels of the single optical trocar under a positive pressure, wherein the insufflating gas presses against the breast tissue, pressing the breast tissue away to create a cavity in an operative field next to the tumor;
within the cavity created next to the tumor, dissecting the tumor free with a surgical instrument inserted through one of the working channels;
removing the tumor through one of the working channels of the single optical trocar;
wherein the inserting, guiding, insufflating, dissecting and removing are all performed with the single optical trocar such that the single optical trocar is the only trocar used; and
inserting a dilatation balloon through one of the working channels to create an initial cavity for insufflating gas.

US Pat. No. 10,426,493

PATIENT-SPECIFIC GLENOID GUIDES

Biomet Manufacturing, LLC...

1. A system for a shoulder joint of a patient comprising: a glenoid guide comprising:an upper surface;
a lower surface that is shaped as a patient-specific surface that is configured as a negative surface of at least a portion of a glenoid face based on a three-dimensional image of a shoulder joint of a patient reconstructed preoperatively from image scans of the shoulder joint of the patient;
a first drill guide extending from the upper surface along a first alignment axis configured preoperatively with a patient-specific orientation and insertion location for guiding a first glenoid implant into the glenoid face;
a second drill guide extending from the upper surface along a second alignment axis configured preoperatively with a patient-specific orientation and location for guiding a second glenoid implant into the glenoid face;
a baseplate implant configured to engage the glenoid face and having a plurality of fixation holes therein; and
a finishing drill guide configured to couple with the baseplate implant, the second drill guide including a plurality of drilling bores that communicate with the fixation holes.

US Pat. No. 10,426,492

PATIENT SPECIFIC ALIGNMENT GUIDE WITH CUTTING SURFACE AND LASER INDICATOR

Biomet Manufacturing, LLC...

1. A patient-specific guiding system for guiding an instrument relative to a portion of an anatomical feature of a patient, the patient-specific guiding system comprising:a patient-specific guide having:
a first portion having a first patient-specific inner surface that is configured to conform to and mate with a first surface of the anatomical feature in only one position and an outer surface opposite the first patient-specific inner surface, the first portion including a guide surface for use in guiding the instrument relative to the anatomical feature and a fixation feature for coupling the first portion to the first surface of the anatomical feature; and
a second portion having a second patient-specific inner surface that is configured to conform to and mate with a second surface of the anatomical feature in only one position and an outer surface opposite the second patient-specific inner surface, the second portion being removably connected to the first portion;
wherein the first and second patient-specific inner surfaces each have a three dimensional contour that is configured to nest and closely conform to the first and second surfaces, respectively, of the anatomical features, to align the guide relative to the anatomical feature; and
wherein the first and second portions are non-adjustably conformable with the first and second surfaces when the first and second portions are connected to each other to facilitate engagement in a single desired orientation; and
wherein the guide surface is an opening in the first patient-specific inner surface that is configured to receive the instrument.

US Pat. No. 10,426,491

TANGENTIAL FIT OF PATIENT-SPECIFIC GUIDES

Biomet Manufacturing, LLC...

1. A bone preparation guide comprising:a first patient-specific portion based on image data of a specific patient's bone and configured to match a bone surface on the specific patient;
a first bone-contacting portion based on image data of the specific patient's bone and configured to match the bone surface; and
an intermediate portion configured to be a bone-facing portion supported by the first patient-specific portion and the first bone-contacting portion;
wherein the bone contacting portion includes bone contacting members including pointed tips.

US Pat. No. 10,426,490

TRANSPARENT PRESSURE DRESSING DEVICE AND METHODS FOR ENABLING HEMOSTASIS OF BLOOD

1. A transparent pressure dressing device configured to enable hemostasis of blood in a perforation of a blood vessel, the transparent pressure dressing device comprising;a rectangular plate shaped artificial hand component, wherein the artificial hand component comprises a protuberance section positioned proximal to a distal edge of the artificial hand component; and
one or more adhesive fins extending from an upper surface of the artificial hand component, wherein the protuberance section of the artificial hand component is configured to be gradually pressed against the perforation on the blood vessel to enable hemostasis of the blood, and the adhesive fins are configured to adhere to a body surface of a patient proximal to the perforation on the blood vessel; and
further comprising one or more metal weight components positioned above and conforming to the upper surface of the artificial hand component, wherein each metal weight component is configured to add weight to the artificial hand component to increase the pressure applied to enable hemostasis of the blood at the perforation of the blood vessel; and
further comprising a plurality of magnetic pieces positioned on an upper surface of each metal weight component, wherein the magnetic pieces allow attachment of the one or more metal weight components above the artificial hand component to generate required compression on body's tissues proximal to the perforation of the blood vessel.

US Pat. No. 10,426,489

ENDOSCOPIC REPOSABLE SURGICAL CLIP APPLIER

Covidien LP, Mansfield, ...

12. An endoscopic assembly for use with a reposable surgical clip applier, the endoscopic assembly comprising:an outer tube defining a longitudinal axis extending therealong, and a pair of transverse channels formed therein;
a pusher bar slidably supported within the outer tube, wherein a proximal portion of the pusher bar is received within the pair of transverse channels; and
a spindle assembly slidably supported within the outer tube, a surface of the spindle supporting a fin that is in selective engagement with a proximal portion of the pusher bar,
wherein during a distal advancement of the spindle, the fin urges the pusher bar in a distal direction.

US Pat. No. 10,426,481

IMPLANTABLE LAYER ASSEMBLIES

Ethicon LLC, Guaynabo, P...

1. A staple cartridge assembly for use with a surgical instrument, wherein the staple cartridge assembly comprises:a staple cartridge defining a longitudinal axis, the staple cartridge comprising:
a cartridge body; and
a plurality of staples stored in the cartridge body; and
a compressible tissue thickness compensator, comprising:
a deck-facing side;
a tissue-facing side;
a first portion; and
a second portion, wherein the second portion comprises a curved depression on the tissue-facing side of the compressible tissue thickness compensator, wherein the curved depression partially extends through the second portion of the compressible tissue thickness compensator, and wherein the curved depression is transverse to the longitudinal axis defined by the staple cartridge.

US Pat. No. 10,426,480

CUTTING RING ASSEMBLY WITH RIGID CUTTING MEMBER

Covidien LP, Mansfield, ...

1. An anvil assembly comprising:an anvil center rod;
an anvil head supporting an anvil plate having a plurality of staple deforming pockets; and
a cut ring assembly supported within the anvil head adjacent the anvil plate, the cut ring assembly including a backup member, an intermediate member and a cutting ring body, the backup member formed of a single integral material, wherein the intermediate member is formed of a thin, rigid material and is sandwiched directly between the backup member and the cutting ring body, wherein the intermediate member is in direct contact with the backup member and the cutting ring body, the thin, rigid material being formed of a material having a hardness less than the hardness of the backup member and greater than the hardness of the cutting ring body.

US Pat. No. 10,426,477

STAPLE CARTRIDGE ASSEMBLY INCLUDING A RAMP

Ethicon LLC, Guaynabo, P...

1. A staple cartridge assembly, comprising:a cartridge body comprising a proximal end and a distal end;
a deck;
a longitudinal row of staple cavities defined in said deck;
a plurality of staples removably stored in said row of staple cavities, wherein each said staple comprises:
a base comprising a groove;
a first leg extending from said base; and
a second leg extending from said base; and
a ramp configured to move from said proximal end toward said distal end to eject said staples from said staple cavities, wherein said ramp travels along a path aligned with said bases of said staples, wherein said first legs are positioned on a first side of said path, wherein said second legs are positioned on a second side of said path, and wherein said groove of said base is configured to receive said ramp as said ramp travels along said path.

US Pat. No. 10,426,476

CIRCULAR FASTENER CARTRIDGES FOR APPLYING RADIALLY EXPANDABLE FASTENER LINES

Ethicon LLC, Guaynabo, P...

1. A fastener cartridge assembly for use with a circular surgical fastening device comprising a circular knife and an anvil, wherein the fastener cartridge assembly comprises:a cartridge body comprising a circular deck, wherein said circular deck comprises an inner edge, wherein said inner edge comprises an inner circular axis having an inner radius, and wherein said circular knife is configured to cut tissue clamped between said circular deck and the anvil along a circular knife path having a knife radius that is less than said inner radius;
a plurality of transverse fastener cavities opening through the circular deck in a transverse cavity zone, wherein each said transverse fastener cavity comprises two cavity ends, wherein one said cavity end of each of the transverse fastener cavities is positioned on a first circular axis having a first radius, and wherein the other said cavity end of each said transverse fastener cavity is positioned on a second circular axis that has a second radius that differs from the first radius;
a plurality of circumferential fastener cavities opening through the circular deck, wherein each of the circumferential fastener cavities are aligned on a third circular axis that comprises a third radius that differs from the first and second radiuses, and wherein the circumferential fastener cavities are not positioned in said transverse cavity zone; and
a plurality of fasteners removably positioned within said fastener cavities, wherein said plurality of fasteners are configured to be ejected from said fastener cavities simultaneously, and wherein said plurality of fasteners comprises:
a plurality of first fasteners comprising a first formed height; and
a plurality of second fasteners comprising a second formed height, wherein said first formed height and said second formed height are different,
wherein said third radius is greater than said inner radius, and
wherein said first radius and said second radius are greater than said third radius.

US Pat. No. 10,426,475

SURGICAL DEVICE

AtriCure, Inc., Mason, O...

1. A medical instrument comprising:a hand-held control at least partially housing a plurality of controls;
a first joint including first joint components that are repositionable with respect to one another within a first degree of freedom;
a second joint operatively coupled to the first joint, the second joint including second joint components that are repositionable with respect to one another within a second degree of freedom, the second degree of freedom being different than the first degree of freedom;
an elongated conduit operatively coupling the hand-held control to at least one of the first joint and the second joint; and,
an occlusion clip deployment end effector removably coupled to a closed-ring occlusion clip;
wherein the plurality of controls comprises a first passive control configured to control repositioning of the first joint among a first position that allows free movement of the first joint across a predetermined range of a motion, and a second position that locks a position of the first joint within the predetermined range of motion; and,
wherein the plurality of controls comprises a second control configured to control repositioning of the second joint.

US Pat. No. 10,426,473

SYSTEM AND METHOD FOR PLICATING A HEART VALVE

Abbott Cardiovascular Sys...

1. A device for connecting together two opposing leaflets of a valve in a patient's heart, comprising:a first clip having a generally U-shape, comprising a first prong and a second prong, and a first bridge connecting the first prong to the second prong;
a second clip having a generally U-shape, comprising a third prong and a fourth prong, and a second bridge connecting the third prong to the fourth prong;
a third clip having a generally U-shape, comprising a fifth prong and a sixth prong, and a third bridge connecting the fifth prong to the sixth prong;
wherein the third prong has a first elongate axis and the fifth prong has a second elongate axis and the third prong and the fifth prong are positioned to extend adjacent to and parallel with the first prong, and are configured to rotate about the first elongate axis and the second elongate axis respectively.

US Pat. No. 10,426,472

DEVICES, SYSTEMS, AND METHODS FOR WOUND CLOSURE

Covidien LP, Mansfield, ...

1. A suture grasper for retrieving a suture from an internal surgical site, the suture grasper comprising:a housing;
an inner shaft extending from the housing and fixed relative thereto, the inner shaft having a tissue-penetrating tip;
an intermediate shaft disposed about the inner shaft, the intermediate shaft extending through a distal opening of an outer shaft and having a plurality of spring fingers movable between a spread position, wherein the spring fingers extend radially outwardly from the inner shaft and surround the inner shaft, and a compressed position, wherein the spring fingers are approximated about the inner shaft; and
the outer shaft disposed about the intermediate shaft and selectively translatable relative to the inner shaft and the intermediate shaft for moving the spring fingers between the spread position and the compressed position, wherein the intermediate shaft is translatable relative to the inner shaft and the outer shaft between a first proximal position, in which free ends of the spring fingers are positioned proximally of a distal region of the inner shaft, and a first distal position, in which the free ends of the spring fingers collectively enclose therein the tissue-penetrating tip of the inner shaft.

US Pat. No. 10,426,471

SURGICAL INSTRUMENT WITH MULTIPLE FAILURE RESPONSE MODES

Ethicon LLC, Guaynabo, P...

22. A powered surgical instrument, comprising:an end effector, comprising:
an actuation member movable through a firing stroke to actuate said end effector; and
a motor operably coupled to said actuation member, wherein said motor is configured to generate at least one rotational motion to move said actuation member through said firing stroke; and
a failure response system, comprising:
a first circuit configured to detect a first operational error of said powered surgical instrument, wherein said first operational error comprises detecting said movement of said firing member and said rotational motion of said motor exceeding a predetermined correlation during said firing stroke;
a second circuit configured to detect a second operational error of said powered surgical instrument, wherein said second operational error comprises detecting failure of at least one of a beginning-of-stroke switch and an end-of-stroke switch; and
a controller, comprising:
a memory;
a processor; and
a storage medium comprising program instructions which, when executed by said processor, cause said processor to:
activate a first failure response mode in response to the detection of said first operational error;
activate a second failure response mode in response to the detection of the first operational error and the second operational error, wherein said first failure response mode and said second failure response mode are different.

US Pat. No. 10,426,470

STAPLING DEVICE WITH RELEASABLE KNIFE CARRIER

Covidien LP, Mansfield, ...

1. A surgical stapling device comprising:an elongate body defining a longitudinal axis and having a proximal portion and a distal portion, the elongate body including a pusher drive member and a knife carrier pusher, the knife carrier pusher movable independently of the pusher drive member;
a reload assembly including a housing including an inner housing portion defining a housing through bore, a staple cartridge supporting a plurality of staples, a pusher assembly movably supported within the housing between a retracted position and an advanced position to eject the plurality of staples from the staple cartridge, and a knife carrier supporting a knife, the knife carrier including first engagement structure;
wherein the knife carrier pusher includes a second engagement structure that is configured to releasably engage the first engagement structure of the knife carrier to couple the knife carrier pusher to the knife carrier, the first engagement structure being movable from a first position engaged with the second engagement structure to a second position disengaged from the second engagement structure; and
a reload member supported on the housing, the reload member having a first portion configured to prevent movement of the first engagement structure from the first position to the second position and a second portion configured to accommodate movement of the first engagement structure from the first position to the second position.

US Pat. No. 10,426,469

SURGICAL INSTRUMENT COMPRISING A PRIMARY FIRING LOCKOUT AND A SECONDARY FIRING LOCKOUT

Ethicon LLC, Guaynabo, P...

1. A surgical instrument, comprising:a shaft comprising a longitudinal axis;
a firing drive comprising a firing member movable along said longitudinal axis;
an end effector, comprising:
a distal end;
a channel configured to receive a staple cartridge;
an anvil; and
a primary lockout configured to block said firing member from being moved toward said distal end if a staple cartridge is not positioned in said channel; and
a secondary lockout actuatable to prevent said firing member from being moved toward said distal end, wherein said secondary lockout is actuated in response to the distal movement of said firing member being blocked by said primary lockout.

US Pat. No. 10,426,468

HANDHELD ELECTROMECHANICAL SURGICAL SYSTEM

Covidien LP, Mansfield, ...

1. A handheld electromechanical surgical device, comprising:a non-sterile power-pack including:
at least one drive component, each drive component having a rotatable drive shaft extending therefrom;
a main processor coupled to the at least one drive component and configured to control each drive component;
a battery coupled to the main processor and the at least one drive component, the battery configured to power each drive component;
an electrical receptacle coupled to the main processor; and
at least one control interface coupled to the main processor, the at least one control interface actuatable to direct the main processor to control a functionality of at least one of the at least one drive component; and
a sterile outer shell housing configured to removably encase the power-pack, the sterile outer shell housing defining a sterile barrier between the power-pack and an exterior of the outer shell housing when encased about the power-pack to enable use thereof in a surgical environment without breaking sterility, the outer shell housing including:
a barrier plate assembly including:
a coupler configured to transmit a rotation from the rotatable drive shaft of each drive component through the outer shell housing, wherein the coupler includes a plurality of rotatable coupling shafts, each rotatable coupling shaft including a proximal end configured to operably couple to a respective rotatable drive shaft to receive rotative forces therefrom, and a distal end projecting from the outer shell housing;
at least one control button in operative registration with each of the at least one control interfaces such that actuation of the at least one control button actuates the at least one control interface in operative registration therewith; and
a pass-through connector configured to transmit electrical communications from the electrical receptacle through the outer shell housing, wherein the pass-through connector includes a proximal end configured to operably couple to the electrical receptacle, and a distal end projecting out of the outer shell housing.

US Pat. No. 10,426,467

SURGICAL INSTRUMENT WITH DETECTION SENSORS

Ethicon LLC, Guaynabo, P...

1. A surgical instrument comprising:a handle assembly;
a shaft coupled to the handle assembly;
an end effector communicatively coupled to the handle assembly through the shaft and comprising a first and second jaw, the handle assembly configured to manipulate the first and second jaws to define an open position and a closed position; and
a sensor apparatus integrally coupled to a distal end of the shaft comprising at least one sensor configured to transmit sensor signals onto patient tissue at a surgical site to directly measure a characteristic of the patient tissue and at least one receiver configured to receive sensor data of the patient tissue based on the transmission of the sensor signals.

US Pat. No. 10,426,466

HANDHELD ELECTROMECHANICAL SURGICAL SYSTEM

Covidien LP, Mansfield, ...

1. An adapter assembly, comprising:an elongate body including a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit;
a switch actuator disposed within the elongate body and being movable between a proximal position, in which the switch actuator actuates a switch, and a distal position;
an actuation bar disposed within the elongate body and being movable between a proximal position and a distal position; and
a latch associated with the switch actuator and the actuation bar, the latch being movable between a first position, in which the latch permits proximal movement of the switch actuator, and a second position, in which the latch prevents proximal movement of the switch actuator, wherein the latch is configured to move from the first position toward the second position in response to the actuation bar moving toward the proximal position.

US Pat. No. 10,426,465

MECHANICAL, HOSE-LESS, CABLE-LESS, RE-USABLE DYNAMIC COMPRESSION BONE STAPLE DELIVERY DEVICE WITH ATTRIBUTES BUILT INTO HANDLE

Zimmer, Inc., Warsaw, IN...

1. A compression bone staple delivery system, comprising:a housing;
a handle attached to the housing;
a shaft disposable within the housing, movable between a proximal orientation and a distal orientation and positionable so that a distal end of the shaft impacts a staple for deploying the staple distally into a desired bone site when the shaft is moved from the proximal orientation to the distal orientation;
a spring configured to bias the shaft toward the distal orientation;
a latch configured to retain the shaft in the proximal orientation;
a coupling attachable to a distal end of the housing;
a staple cartridge housed within the coupling; and
a latch release, the latch release being actuatable to move the latch to a non-restraining orientation so that the shaft moves to the distal orientation, thereby deploying the staple from a position in the staple cartridge into the desired bone site.

US Pat. No. 10,426,462

SIDE LOADING KNOT CUTTER

1. An instrument for securing a knot disposed in surgical suture, the instrument comprising:a shaft comprising:
a cannula having a proximal portion coupled to a handle and a distal portion including a distal end, the cannula extending parallel with a longitudinal axis of the handle, the cannula extending through a distal end of the handle to define a cannulated tip of the shaft; and
a cutting sleeve movably disposed over the cannula and configured to slide over the cannula;
a side-loading channel disposed along a side of the distal portion of the cannula and extending through the distal end of the cannula; and
a user manipulable control portion slidably mounted on an upper surface of the handle, the user manipulable control portion configured for controlling axial movement of the cutting sleeve along the cannula;
wherein the distal end of the cannula comprises a knot pushing surface,
wherein the side-loading channel is configured to receive a suture, and
wherein the cannulated tip is configured for receiving the suture from the side-loading channel.

US Pat. No. 10,426,461

SURGICAL ACCESS DEVICES HAVING A VARIABLE TISSUE APPROACH ANGLE

Ethicon LLC, Guaynabo, P...

1. A surgical access device, comprising:(a) a housing having a top surface, a side surface, and a tapered distal end;
(b) a cannula extending distally from the tapered distal end of the housing, wherein the cannula includes a cylindrical sidewall and an elongate opening disposed in the cylindrical sidewall, wherein the housing and the cannula define a working channel extending therethrough that is sized and configured to receive a surgical instrument;
(c) a cylindrical sleeve that encircles the cylindrical sidewall of the cannula, wherein the cylindrical sleeve overlies the elongate opening;
(d) a seal disposed within the working channel and configured to seal the working channel when no instrument is disposed therethrough; and
(e) a first suture channel, wherein the first suture channel extends through the side surface of the housing, passes directly from the housing to the cannula, extends across the working channel, and extends through the elongate opening and the cylindrical sleeve,
wherein the first suture channel extends at an oblique angle with respect to a central longitudinal axis extending through the cannula, wherein the oblique angle is selectively adjustable.

US Pat. No. 10,426,458

KNOTLESS SUTURE FASTENER INSTALLATION SYSTEM

Edwards Lifesciences Corp...

1. A system for securing a suture, comprising:a deployment tool having a distal shaft and an ejector movable within the distal shaft; and
a subassembly configured to attach to the distal shaft of the deployment tool, the subassembly comprising:
a cartridge having a lumen, wherein a proximal portion of the cartridge lumen is configured to engage the distal shaft of the deployment tool;
a suture fastener positioned within a distal portion of the cartridge lumen, the suture fastener having a clamping structure that is held by the cartridge in a resiliently deformed open condition wherein a suture can pass through the clamping structure, the clamping structure being biased toward a closed position in which the clamping structure resiliently clamps onto a suture passed therethrough; and
a suture snare having a snare portion extending radially into the cartridge and extending axially through the suture fastener in its open condition, the snare portion being adapted to capture and pull a suture proximally through the suture fastener;
wherein when the cartridge is engaged with the deployment tool, movement of the ejector causes the suture fastener to deploy from the cartridge and change from its open condition to its closed condition to clamp onto a suture extending through the suture fastener.

US Pat. No. 10,426,457

SURGICAL FASTENER DEPLOYMENT SYSTEM

Apollo Endosurgery US, In...

1. A tissue fastener deployment system, comprising:a) a handle;
b) a first tubular member having a proximal end and a distal end and defining a longitudinal axis, the proximal end rotatably coupled to the handle;
c) a coil having a tissue-piercing distal tip, the coil rotationally fixed relative to the first tubular member, such that rotation of the first tubular member relative to the handle results in rotation of the coil, wherein when the distal tip of the coil is rotated against tissue the distal tip of the coil is adapted to pierce and engage the tissue;
d) at least one fastener axially displaceable relative to the distal end of the first tubular member and through the coil;
e) a push member longitudinally displaceable relative to the first tubular member and adapted to apply an axial displacement force against the at least one fastener; and
f) an actuator movably coupled relative to the handle, wherein actuating the actuator results in longitudinal displacement of the push member relative to the first tubular member and to apply an axial displacement force against the at least one fastener to deploy one of the at least one fastener from the deployment system.