US Pat. No. 10,392,531

PROCESS FOR REMOVING A BULK MATERIAL LAYER FROM A SUBSTRATE AND A CHEMICAL MECHANICAL POLISHING AGENT SUITABLE FOR THIS PROCESS

BASF SE, Ludwigshafen (D...

14. An aqueous chemical mechanical polishing agent (A), comprising:(a1) a polyether comprising a chain of at least one copolymerized ethylene oxide and at least one copolymerized alkylene oxide having at least 3 carbon atoms, said chain having a statistical, alternating, or block distribution comprising a residue of at least one starter molecule selected from the group consisting of ethylene diamine and a polyethyleneimine; and
(a2) an additional component;
with the exception of a polymer having a mean particle size d50 of 76 run as measured by HPPS dynamic light scattering and prepared by:
Charging under nitrogen 1500 g of deionized water and 4.5 g of hexadecyltrimethylammonium bromide to a reaction flask,
heating the contents of the flask up to 70° C.,
charging, at this temperature, 0.68 g 2,2?-azo-(2-amidinopropane) dihydrochloride to the reaction flask,
simultaneously starting a monomer feed consisting of 630 g of deionized water, 391.5 g styrene, 60 g of methacrylamide as a 15% solution in water, 4.5 g of divinylbenzene, and 2.48 g of hexadecyltrimethylammonium bromide and continually feeding it for 1.5 hours,
starting, at the same time, an initiator feed containing 170 g of deionized water and 2.3 g of 2,2?-azo-(2-amidinopropane) dihydrochloride and continually feeding it to the reaction flask for 2.5 hours,
starting after 1.5 hours from the start of the first monomer feed, a second monomer feed consisting of 255 g of deionized water, 13.5 g of 2-dimethylaminoethyl methacrylate, 0.9 g of hexadecyltrimethylammonium bromide and 31.5 g of styrene and continually feeding it to the reaction flask during 30 minutes,
post-polymerizing the obtained reaction mixture for 2 hours at 70° C. and then cooling it down to room temperature,
thereby obtaining a dispersion of solid polymeric particles with a solids content of 15% by weight.
US Pat. No. 10,392,532

ADHESIVE COMPOSITIONS WITH REPAIR-REWORK ABILITY

Illinois Tool Works, Inc....

1. An adhesive composition comprising:a linear triblock copolymer present at greater than or equal to 30 total weight percent comprising high glass transition temperature subunits Y and Y?, each of the subunits Y and Y? having a high glass transition temperature of from 70° C. to 130° C. with a low glass transition temperature subunit Z having a low glass transition temperature of from ?100° C. to 10° C. intermediate between said high glass transition temperature acrylate subunits to define a structure Y—Z-Y?;
a monomer curable under free radical conditions in which said linear triblock copolymer is dissolved in monomers and cross-linkers;
a blend of at least one of a free radical initiator of a peroxide or a hydroperoxide, and a perester;
an acid chloride or a diacid chloride with pyridine; and
antioxidant inhibitor(s).
US Pat. No. 10,392,533

ADHESIVE SHEET

NITTO DENKO CORPORATION, ...

1. An adhesive sheet comprising a substrate and an adhesive layer,wherein the substrate consists of a substrate layer containing an ester-based thermoplastic polyurethane and a surface protective layer containing a component selected from the group consisting of an acrylic-based resin that is a crosslinked product comprising a (meth)acrylic-based polymer having a hydroxyl value of 20 to 120 KOH mg/g and a crosslinking agent, and a fluorine-based resin,
wherein the surface protective layer is provided as the outermost surface of the adhesive sheet, and
the adhesive layer is directly on the substrate layer,
a static friction coefficient of the substrate being 0.05 or more and 1.50 or less, and an absolute value of a ?L* value of the substrate being 0.01 or more and 45.00 or less, wherein the ?L* value represents an index of stainproof property.
US Pat. No. 10,392,280

FIBER BUNDLE FOR BEARING MICROORGANISMS

SHANGHAI FANQING ENVIRONM...

1. A fiber bundle for bearing microorganisms comprisingfiber filaments wound into a ring shape or having two ends of fiber filaments bound into a bundle;
wherein the cross section of the fiber filaments is in a non-circular shape selected from oval shape, cashew shape, triangular shape, pentagonal shape, square shape, prismatic shape, Y shape, plum shape, cruciform shape, or Union Jack shape; and
wherein the fiber filaments have an outer surface that is smooth; and
wherein the fiber bundle has a specific surface area of from 6,600 m2/m3 to 12,000 m2/m3 and a bearing capacity of from 108 kg/m3 to 135 kg/m3.
US Pat. No. 10,392,537

PROPYLENE POLYMER-BASED HOT MELT ADHESIVE COMPOSITION EXHIBITING FAST SET TIME AND ARTICLES INCLUDING THE SAME

H.B. Fuller Company, St....

1. A hot melt adhesive composition comprising:from about 15% by weight to no greater than 75% by weight propylene polymer derived from at least 50% by weight propylene, based on the weight of the propylene polymer, and optionally an alpha-olefin comonomer other than propylene, the propylene polymer exhibiting a heat of fusion of from about 5 Joules per gram (J/g) to 60 J/g;
from 5% by weight to about 50% by weight ethylene alpha-olefin copolymer derived from at least 50% by weight ethylene, based on the weight of the ethylene alpha-olefin polymer, and at least one alpha-olefin comonomer having at least three carbon atoms, the ethylene alpha-olefin copolymer having a density of no greater than 0.90 g/cm3;
at least 35% by weight of a polymer selected from the group consisting of the propylene polymer, the ethylene alpha-olefin copolymer, and combinations thereof, and
from 18% by weight to about 37% by weight of a wax component exhibiting a melting point greater than 80° C. and a heat of fusion of at least 200 J/g,
the composition exhibiting a set time of no greater than 1.5 seconds at an application temperature of at least 149° C.
US Pat. No. 10,392,539

CRASH DURABLE EPOXY ADHESIVE COMPOSITIONS HAVING IMPROVED LOW-TEMPERATURE IMPACT RESISTANCE AND WASH OFF RESISTANCE

Dow Global Technologies L...

1. A one-component adhesive composition comprising:one or more epoxy resins;
at least one polyurethane based toughener containing aliphatic diisocyanate groups that are blocked or capped with bisphenol A or diisopropyl amine;
at least one epoxy functionalized amphiphilic block copolymer having a molecular weight from 5,000 g/mole to 20,000 g/mole; and
one or more epoxy curing agents,
wherein the adhesive composition has a viscosity of less than 300 pascal second, and exhibits an improvement in wash off resistance in comparison to a similar adhesive composition that does not include an epoxy functionalized amphiphilic block copolymer.
US Pat. No. 10,392,540

ADHESIVE COMPOSITION AND AN ARTICLE MANUFACTURED THEREFROM

3M Innovative Properties ...

1. An adhesive composition, based on the total weight of the composition, comprising the following components in solid content percentage:(A) 15% to 50% by weight of a first epoxy resin with a weight average molecular weight Mw of 8,000 g/mol or more;
(B) 3% to 15% by weight of a second epoxy resin with a weight average molecular weight Mw of 200 to 3,000 g/mol;
(C) 20% to 50% by weight of a carboxyl terminated polyester or derivates thereof;
(D) 0.1% to 2.5% by weight of a first curing agent capable of reacting with epoxy group;
(E) 0.1% to 2.5% by weight of a second curing agent capable of reacting with carboxyl group; and
(F) 0% to 40% by weight of a flame retardant.
US Pat. No. 10,392,541

HOT MELT ADHESIVE

1. A hot melt adhesive comprising:(A) a polar functional group-modified conjugated diene-based polymer wherein the polar functional group is an acid anhydride group and the conjugated diene-based polymer comprises a block copolymer of a vinyl-based aromatic hydrocarbon block and a conjugated diene compound block,
(B) at least one aliphatic polyester-based resin selected from a polylactic acid-based resin, polybutylene succinate, polyhydroxybutyric acid, and combinations thereof,
(C) an amorphous ethylene-based copolymer,
(D) a crystalline polypropylene resin with a melting point of about 120° C. or higher, and
(E) a tackifier resin;wherein (A) is present in an amount of about 1 to about 20 parts by weight, (B) is present in an amount of about 5 to about 50 parts by weight, (C) is present in an amount of about 5 to about 60 parts by weight, (D) is present in an amount of about 3 to about 30 parts by weight, and (E) is present in an amount of about 20 to about 60 parts by weight, all based on 100 parts by weight of the total weight of the components (A) to (E).
US Pat. No. 10,391,003

DISPOSABLE ARTICLE, AND METHOD FOR PRODUCING AND METHOD FOR SELLING THE SAME

1. A disposable article, comprising:an air permeable sheet having air permeability;
a fiber sheet having liquid diffusibility; and
an elastic member located between the air permeable sheet and the fiber sheet,
wherein the air permeable sheet, the fiber sheet, and the elastic member are joined by applying an adhesive to a surface of the elastic member and then attaching the air permeable sheet and the fiber sheet to the elastic member while the elastic member is in a stretched state, and
a transpiration rate of the disposal article determined by the equation:
Transpiration rate (%)={(W0?Wt)/(W0?Wt)}×100, exceeds 40%, where
W is a weight of a test piece of the disposal article and a petri dish under a standard condition of 20° C. and 65% RH, W0 is a weight of the test piece and the petri dish to which 0.1 mL of water is added, and Wt is a weight of the test piece and the petri dish measured after the 0.1 mL of water is added and left in the standard condition for 20 minutes.
US Pat. No. 10,392,542

LATENT TWO-PART POLYURETHANE ADHESIVES CURABLE WITH INFRARED RADIATION

DOW GLOBAL TECHNOLOGIES L...

1. A composition comprising a polyol component and an isocyanate component, wherein:a) the polyol component includes;
i) one or more polyols having a hydroxyl equivalent weight of 400 to 2000 and a nominal hydroxyl functionality of 2 to 3;
ii) one or more aliphatic diol chain extenders;
iii) one or more latent room temperature organometallic catalysts; and
iv) one or more multifunctional polyols having a functionality of about 5 to about 8;
b) the polyisocyanate component includes:
iv) one or more polyisocyanate compounds;
wherein the polyisocyanate component and the polyol component are contacted at an isocyanate index of about 1.0 to about 1.8; and both of v) one or more carboxylic acid-blocked cyclic amidine compounds blocked with an aliphatic carboxylic acid having 1 to 24 carbon atoms or a mixture of two or more thereof, and vi) one or more phenol-blocked cyclic amidine compounds are located in the polyol component or the isocyanate component and the composition is useful as a two-component polyurethane adhesive composition.
US Pat. No. 10,392,798

ACOUSTIC CEILING BOARD WITH IMPROVED AESTHETICS

AWI Licensing LLC, Wilmi...

1. An acoustical panel having a front side opposite a concealed side, the acoustical panel comprising:a substrate;
a coated non-woven veil comprising a coating applied to a non-woven veil, the non-woven veil comprising having an airflow resistance of greater than 45 mks rayls and comprising:
from about 20 wt. % to about 60 wt. % fibers; and
from about 40 wt. % to about 80 wt. % of a filler that is non-fibrous;
said percentages based on the weight of the non-woven veil; and
wherein the total amount of coating that is present on the non-woven veil ranges from about 110 dry g/m2 to about 135 dry g/m2.
US Pat. No. 10,392,543

REACTIVE RESINS AND FORMULATIONS FOR LOW REFRACTIVE INDEX AND LOW DIELECTRIC CONSTANT APPLICATIONS

1. A highly fluorinated silicone resin comprising the reaction products of:an M type monomer having a chlorosilane function; a first T type monomer having at least one fluoroalkane group; a second T type monomer having a (meth)acryloyl functional group; optionally, a D type monomer; and optionally, a Q type monomer;
said silicone resin having a fluorine content of at least 55 weight percent based on the total weight, a refractive index at 25° C. of less than 1.4, and an uncured viscosity of 1000 to 9000 cps at 25° C.
US Pat. No. 10,392,545

1,2,3,3,3-PENTAFLUOROPROPENE PRODUCTION PROCESSES

THE CHEMOURS COMPANY FC, ...

1. An azeotropic composition comprising from about 81.0 mole percent to about 55.0 mole percent HF and from about 19.0 mole percent to about 45.0 mole percent 1,1,1,2,3-pentafluoropropane at a temperature of from about ?20° C. to about 135° C. and at a pressure of from about 4 psi (27.5 kPa) to about 550 psi (3792 kPa) wherein the composition comprises a liquid and a vapor.
US Pat. No. 10,392,546

COMPOSITION FOR HEAT CYCLE SYSTEM, AND HEAT CYCLE SYSTEM

AGC Inc., Chiyoda-ku (JP...

1. A composition for a heat cycle system, which comprises a working fluid for heat cycle containing at least one unsaturated fluorinated hydrocarbon compound selected from a compound having at least one carbon-carbon unsaturated bond in its molecule represented by the following formula (I), anda refrigerant oil having a breakdown voltage of at least 25 kV, a hydroxy value of at most 0.1 mgKOH/g, and a kinematic viscosity at 40° C. of from 5 to 200 mm2/s and a kinematic viscosity at 100° C. of from 1 to 100 mm2/s:
CxFyRz  (I)wherein R is H or Cl, x is an integer of from 2 to 6, y is an integer of from 1 to 12, and z is an integer of from 0 to 11, provided that 2x?y+z?2.
US Pat. No. 10,392,547

SUPER-COOLING RELEASE MATERIAL AND METHOD FOR PRODUCING SAME

DENSO CORPORATION, Kariy...

1. A supercooling release material which releases a supercooled state of a cold storage material including one or more types of alkylammonium halide aqueous solutions that generate a hydrate by being cooled to a hydrate generation temperature or lower, the supercooling release material comprising:an alkylammonium ion included in the cold storage material; and
a metal halide complex ion which has, as a constituent element, a halogen element included in the cold storage material, wherein:
a metal element included in the metal halide complex ion is at least one of Cu, Ag, Zn, Cd, Au, Cr, Mn, Fe, Co, Ni, Mo, Tc, Ru, Rh, Re, Os, Ir, and Pt.
US Pat. No. 10,392,292

COATED SUBSTRATE FOR SOLAR CONTROL

AGC GLASS EUROPE, Louvai...

1. A transparent substrate coated with an infrared-reflecting layer, wherein the substrate is a glass comprising a composition which has a redox lower than 15%, characterized by an infrared reflection RIRV between 780 and 2500 nm such that RIRV?1.087*TLV, TLV being the light transmission of the glass between 380 and 780 nm, and in that the infrared-reflecting layer is characterized by a light transmission TLC between 380 and 780 nm such that TLC?1.3*TIRC, TIRC being the infrared transmission of the layer between 780 and 2500 nm.
US Pat. No. 10,392,550

SPACER FLUID COMPOSITIONS, METHODS, AND SYSTEMS FOR AQUEOUS BASED DRILLING MUD REMOVAL

Saudi Arabian Oil Company...

1. A wellbore fluid system comprising:an aqueous mud in a wellbore; and
a spacer fluid in contact with the aqueous mud in the wellbore, the spacer fluid comprising:
an emulsion comprising an aqueous external phase and a hydrocarbon-based internal phase;
a surfactant package comprising:
one or more surfactants having the chemical structure R(OC2H4)9—OH, where R is a hydrocarbyl having from 12 to 14 carbon atoms and the surfactant has a hydrophilic-lipophilic balance from 11 to 15; and
at least one additive that modifies the rheology of the spacer fluid, the density of the spacer fluid, or both;in which:the density of the spacer fluid, as measured by American Petroleum Institute Recommended Practice 13B-1, is 5% to 20% greater than the density of the aqueous mud as measured by American Petroleum Institute Recommended Practice 13B-1; and
the difference between the yield point of the aqueous mud, as measured by American Petroleum Institute Recommended Practice 13B-1, and the yield point of the spacer fluid, as measured by American Petroleum Institute Recommended Practice 13B-1, is less than or equal to 15 lbf/100 ft2.
US Pat. No. 10,393,319

KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS

Ecolab USA Inc., St. Pau...

1. A method for inhibiting hydrate formation in a fluid comprising water and a gas, the method comprising contacting the fluid with an effective amount of a hydrate inhibitor composition comprising from about 20 to about 55 wt. % of a nonpolar solvent; from about 1 to about 15 wt. % of a polar solvent; and from about 0.1 to about 50 wt. % of a polymer, an oligomer, a dendrimer, or an acid or salt thereof.
US Pat. No. 10,392,554

UREA HYDROCHLORIDE COMPOSITIONS AND ASSOCIATED METHODS

1. A method for treating a system, the method comprising:providing a composition comprising HCl, urea, complex substituted keto-amine-hydrochloride, at least one alcohol selected from the group consisting of isopropyl alcohol and propargyl alcohol, an ethoxylate, and at least one ketone selected from the group consisting of methyl vinyl ketone, acetone, and acetophenone; and
inserting the composition into at least one of an oil well and a gas well;
said system comprising at least one of a toe preparation system, a squeeze cementing system, a system for the hydration of a gelled based system, and a system for spearhead acid squeeze soaking.
US Pat. No. 10,396,395

SOLID ELECTROLYTE MATERIAL AND METHOD FOR PRODUCING THE SAME

TOKYO INSTITUTE OF TECHNO...

1. A solid electrolyte material comprising a sulfide composition represented by a composition formula Li4?4y?x?zP4+1+y?xP5+xS4?zXz (Li4?4y?x?zP1?yS4?zXz), wherein 0.2?x<1.0, 0?z?0.2, and 0?y?0.075, andX is at least one of F, Cl, N and OH, and
the solid electrolyte material has a peak at a position of 2?=17.8°±0.1°, 19.1°±0.1°, 21.7°±0.1°, 23.8°±0.1° and 30.85°±0.1° in X-ray diffraction measurement using a CuK? ray.
US Pat. No. 10,392,298

PROCESS FOR COATING A GLASS SUBSTRATE WITH AN AQUEOUS FLUROROPOLYMER COATING

ARKEMA INC., King of Pru...

1. An aqueous fluoropolyrner coated substrate comprising a substrate having adhered to at least one surface a two layer coating wherein said first layer consists of:1) at least one hydroxy-functional polyurethane,
2) at least one polyisocyanate,
3) at least one organosilane coupling agent,
4) optionally one or more additives selected from the group consisting of coalescent agents, pigments, dyes, wetting agents, UV absorbers, and heat Stabilizers;and wherein said second layer comprises1) a hydroxy-functional fluoropolymer,
2) a hydrophilic aliphatic polyisocyanate,
3) optionally one or more additives selected from the group consisting of pigments, coalescent agents, wetting agents, UV absorbers, and heat stabilizers; andwherein said first and second layers are intertwined at the interface.
US Pat. No. 10,390,505

SOYBEAN VARIETY 5PVKC48

PIONEER HI-BRED INTERNATI...

1. A plant or a seed of soybean variety 5PVKC48, representative seed of the variety having been deposited under ATCC Accession Number PTA-125912.
US Pat. No. 10,390,506

PLANTS AND SEEDS OF HYBRID CORN VARIETY CH190690

Monsanto Technology LLC, ...

1. A seed of hybrid corn variety CH190690, produced by crossing a first plant of variety CV749310 with a second plant of variety CV692417, wherein representative seeds of said varieties CV749310 and CV692417 are deposited under ATCC Accession Nos. PTA-124502 and PTA-125242, respectively.
US Pat. No. 10,392,557

MULTI-DYE MICROPARTICLES

DNA Medicine Institute, I...

1. A method for manufacturing fluorescing hydrogel microparticles, the method comprising:adding at least two fluorescent dyes to a hydrogel prepolymer mixture;
mixing the mixture so as to distribute the at least two fluorescent dyes uniformly through the prepolymer mixture; and
applying ultraviolet light to a portion of the mixture to form a stably polymerized microparticle, such that at least one fluorescent dye does not leach from the microparticle, wherein the ratio of the at least two fluorescent dyes is selected to provide a signature for identifying the microparticle from other microparticles.
US Pat. No. 10,390,507

SORGHUM HYBRID XSW5902

PIONEER HI-BRED INTERNATI...

1. An F1 hybrid sorghum variety XSW5902 seed produced by crossing a first plant of variety PH1699FW with a second plant of variety PH2707MW, representative seed of the varieties PH1699FW and PH2707MW having been deposited under ATCC Accession Numbers PTA-125662 and PTA-125075 respectively.
US Pat. No. 10,396,399

LIQUID ELECTROLYTE, AND METHOD FOR MANUFACTURING PHOSPHATE

DAIKIN INDUSTRIES, LTD., ...

1. An electrolyte solution comprising:a solvent;
an electrolyte salt; and
a phosphate in an amount of 0.001 to 15 mass % relative to the solvent, the phosphate being represented by the following formula (1):
(R11O)(R12O)PO2Mwherein R11 and R12 may be the same as or different from each other, and are individually represented by Rf11CH2—, wherein Rf11 is a C1-C10 linear or branched fluoroalkyl group; and M is at least one selected from the group consisting of Li, Na, K, and Cs.
US Pat. No. 10,390,508

MAIZE HYBRID X03M275

PIONEER HI-BRED INTERNATI...

1. A seed of hybrid maize variety X03M275, representative seed produced by crossing a first plant of variety PH41W6 with a second plant of variety PH1W4R, wherein representative seed of the varieties PH41W6 and PH1W4R have been deposited under ATCC Accession Numbers PTA-124779 and PTA-121351, respectively.
US Pat. No. 10,390,509

MAIZE INBRED PH42CV

PIONEER HI-BRED INTERNATI...

1. A seed, plant, plant part, or plant cell of inbred maize variety PH42CV, representative seed of the variety having been deposited under ATCC accession number PTA-125658.
US Pat. No. 10,392,560

COMPOSITIONS AND METHODS FOR SELECTIVELY ETCHING TITANIUM NITRIDE

ENTEGRIS, INC., Billeric...

1. A composition for selectively removing titanium nitride and/or photoresist etch residue material from the surface of a microelectronic device having same thereon, said composition comprising at least one oxidizing agent, at least one etchant, at least one corrosion inhibitor, and at least one solvent,wherein the composition is substantially devoid of hydrogen peroxide
wherein the at least one corrosion inhibitor comprises a cationic quaternary species selected from the group consisting of cationic quaternary salts such as benzalkonium chloride, benzyldimethyldodecylammonium chloride, myristyltrimethylammonium bromide, dodecyltrimethylammonium bromide, hexadecylpyridinium chloride, Aliquat 336, benzyldimethylphenylammonium chloride, Crodaquat TES, Rewoquat CPEM, hexadecyltrimethylammonium p-toluenesulfonate, hexadecyltrimethylammonium hydroxide, 1-methyl-1?-tetradecyl-4,4?-bipyridium dichloride, alkyltrimethylammonium bromide, amprolium hydrochloride, benzethonium hydroxide, benzethonium chloride, benzyldimethylhexadecylammonium chloride, benzyldimethyltetradecylammonium chloride, benzyldodecyldimethylammonium bromide, benzyldodecyldimethylammonium chloride, cetylpyridinium chloride, choline p-toluenesulfonate salt, dimethyldioctadecylammonium bromide, dodecylethyldimethylammonium bromide, dodecyltrimethylammonium chloride, ethylhexadecyldimethylammonium bromide, Girard's reagent, hexadecyl(2-hydroxyethyl)dimethylammonium dihydrogen phosphate, dexadecylpyridinium bromide, hexadecyltrimethylammonium bromide, hexadecyltrimethylammonium chloride, methylbenzethonium chloride, Hyamine® 1622, Luviquat™, N,N?,N?-polyoxyethylene (10)-N-tallow-1,3-diaminopropane liquid, oxyphenonium bromide, tetraheptylammonium bromide, tetrakis(decyl)ammonium bromide, thonzonium bromide, tridodecylammonium chloride, trimethyloctadecylammonium bromide, 1-methyl-3-n-octylimidazolium tetrafluoroborate, 1-decyl-3-methylimidazolium tetrafluoroborate. 1-decyl-3-methylimidazolium chloride, tridodecylmethylammonium bromide, dimethyldistearylammonium chloride, and hexamethonium chloride, and
wherein the etchant comprises a species selected from the group consisting of H2ZrF6 , H2TiF6, HPF6, HF, ammonium fluoride, tetrafluoroboric acid, hexafluorosilicic acid, tetrabutylammonium tetrafluoroborate (TBA-BF4), ammonium hexafluorosilicate, ammonium hexafluorotitanate, tetraalkylammonium fluoride (NR1R2R3R4F), tetraalkylammonium hydroxide (NR1R2R3R4OH), where R1, R2, R3, R4 may be the same as or different from one another and is selected from the group consisting of straight-chained or branched C1-C6 alkyl groups, weak bases, and combinations thereof.
US Pat. No. 10,390,510

PLANTS AND SEEDS OF HYBRID CORN VARIETY CH380080

Monsanto Technology LLC, ...

1. A seed of hybrid corn variety CH380080, produced by crossing a first plant of variety CV077335 with a second plant of variety CV581707, wherein representative seeds of said varieties CV077335 and CV581707 are deposited under ATCC Accession Nos. PTA-124513 and PTA-125247, respectively.
US Pat. No. 10,391,535

PROCESS FOR FORMING ALUMINUM ALLOY PARTS WITH TAILORED MECHANICAL PROPERTIES

Magna International Inc.,...

1. A process for making a shaped-part from a heat-treatable aluminum alloy blank, comprising:providing a heat-treatable aluminum alloy blank in a hardened temper state;
heating a first portion of the blank to a predetermined first temperature of between about 150° C. and about 300° C. for a predetermined first length of time lasting less than about 40 seconds;
heating a second portion of the blank to a predetermined second temperature of between about 150° C. and about 300° C. for a predetermined second length of time lasting less than about 40 seconds; and
prior to either of the first portion and the second portion cooling to a temperature below about 130° C., forming the blank within the first portion and within the second portion into the shape of the shaped-part,wherein the hardened temper state is one of a T4, T5, T6, T7 and T7x temper state.
US Pat. No. 10,392,304

CEMENT GRINDING ADDITIVE FOR ENABLING PVC EQUIPMENT USE

GCP Applied Technologies ...

1. A method for manufacturing cement, comprising:introducing a cement grinding additive composition into a manufacturing operation whereby cement clinker and precursor materials are ground into cement, the cement grinding additive composition being introduced through PVC equipment comprising pipes, valves, storage tanks, fittings, or combination thereof;
the cement grinding additive composition comprising:
(a) at least one amine cement grinding additive comprising triisopropanolamine, diethanolisopropanolamine, diisopropanolethanolamine, tetrahydroxyethylethylenediamine, tetrahydroxy-isopropylethylenediamine, triethanolamine, methyldiethanolamine, diethanolamine, or mixtures thereof, the at least one amine cement grinding additive being present in an amount of 5.0 to 99.0 percent by weight of the cement grinding additive composition;
(b) an air detraining agent selected from the group consisting of (i) ethoxylated, propoxylated fatty alcohol or alkylphenol, (ii) polyalkoxylated polyalkylene polyamine, and (iii) mixture thereof, the air detraining agent being present in an amount of 0.1 to 5.0 percent by weight of the cement grinding additive composition;
(c) a biopolymer polysaccharide gum selected from the group consisting of Diutan, Welan, and Xanthan, the gum being present in an amount of 0.01 to 1.0 percent by weight of the cement grinding additive composition; and
(d) water in amount of 0.10 to 60 percent by weight of the cement grinding additive composition;
the foregoing components (a), (b), (c), and (d) of the cement grinding additive composition uniformly mixed together whereby said air detraining agent is uniformly disbursed throughout the cement grinding additive composition during introduction to the cement clinker and precursor materials;
grinding the cement clinker, precursor materials, and cement grinding additive composition together to obtain ground cement comprising the air detraining agent uniformly disbursed throughout the ground cement.
US Pat. No. 10,395,633

SOUND INSULATING SHEET MATERIAL WITH A CELLULAR STRUCTURE INCLUDING GELATINE AND/OR A PROCESS FOR PRODUCING THE SAME

ACOUSTIC SPACE PTY LTD, ...

1. A composition for producing a sheet material with a cellular structure, the composition including the following components:(a) about 5 to about 25 weight % gelatine,
(b) about 25 to about 60 weight % filler material, wherein the density of the filler material is about 2.0 to about 5.0 g/cm3,
(c) about 15 to about 40 weight % water,
(d) a cellular structure promoting agent, wherein the cellular structure promoting agent is selected from a composition including a peroxide group or a persulfate group, and
(e) an alkaline earth metal chloride.
US Pat. No. 10,390,512

HYBRID CORN VARIETY 93677237

Agrigenetics, Inc., Indi...

1. A seed of the hybrid corn variety 93677237, produced by crossing a first plant of variety SLM15 with a second plant of variety 7MMDX3062, wherein representative seed of said varieties SLM15 and 7MMDX3062 have been deposited under ATCC Accession numbers PTA-12586 and PTA-124383, respectively.
US Pat. No. 10,390,513

SOYBEAN CULTIVAR S170107

M.S. Technologies, L.L.C....

1. A plant of soybean cultivar S170107, representative seed of said soybean cultivar having been deposited under ATCC Accession No. PTA-125461.
US Pat. No. 10,391,538

METHOD OF MANUFACTURING HOT DEEP DRAWN STEEL PARTS OF SHEET METAL

Zapadoceska Univerzita V ...

1. A hot deep drawing method of manufacturing steel parts comprising:(a) heating a sheet metal blank to bring the sheet metal blank into austenitic condition;
(b) subsequently cooling critical-deformation locations of the sheet metal blank to a temperature below an austenite temperature, wherein the critical-deformation locations comprise undercooled austenite regions of the sheet metal blank and/or regions of mixed microstructures; and
(c) subjecting the sheet metal blank to a forming process comprising a forming tool.
US Pat. No. 10,392,307

DIMENSIONALLY STABLE GEOPOLYMER COMPOSITION AND METHOD

UNITED STATES GYPSUM COMP...

1. An aluminosilicate geopolymer cementitious composition comprising a reaction product of:a cementitious reactive powder comprising:
33 to 81.6% by weight a thermally activated aluminosilicate mineral comprising Class C fly ash;
4.65 to 43% by weight calcium sulfoaluminate cement, wherein the calcium sulfoaluminate cement in an amount of 10-100 parts by weight per 100 parts by weight of thermally activated aluminosilicate mineral; and
4.35 to 40% by weight calcium sulfate, wherein the calcium sulfate selected from the group consisting of calcium sulfate dihydrate, calcium sulfate hemihydrate, anhydrous calcium sulfate and mixtures thereof, the calcium sulfate in an amount of up to 100 parts by weight per 100 parts by weight of calcium sulfoaluminate cement; and
a chemical activator selected from the group consisting of alkali metal salt, alkali metal base and mixtures thereof in an amount equal to about 1.0 to about 6.0% by weight based on total weight of the cementitious reactive powder, and
at least one of the group consisting of superplasticizers, air entraining agents, defoaming agents, organic rheology control agents, and film-forming polymers; and water,
wherein the calcium sulfate has an average particle size from about 1 to about 100 microns.
US Pat. No. 10,390,514

GARDEN BEAN VARIETY ‘PV-857’

POP VRIEND RESEARCH B.V.,...

1. A seed of garden bean variety designated ‘PV-857’, wherein a representative sample of seed of said variety has been deposited under NCIMB Accession Number 42983.
US Pat. No. 10,392,570

METHOD FOR THE HYDROTREATMENT OF DISTILLATE CUTS USING A CATALYST MADE FROM AN AMORPHOUS MESOPOROUS ALUMINA HAVING HIGH CONNECTIVITY

IFP Energies Nouvelles, ...

1. A process for hydrotreatment of at least one liquid hydrocarbon feedstock having a weighted average temperature of more than 380° C., said process comprising:hydrotreating said liquid hydrocarbon feedstock at a temperature of between 250° C. and 430° C., at a total pressure of between 4 MPa and 20 MPa, with a ratio of volume of hydrogen to volume of liquid hydrocarbon feedstock of between 200 and 2,000 liters per liter and at an Hourly Volume Velocity, defined by the ratio of the volume flow of liquid hydrocarbon feedstock to the volume of catalyst fed into the reactor, of between 0.5 and 5 h?1,
wherein said hydrotreating is performed in the presence of at least one catalyst containing at least one metal from Group VIB and/or at least one metal from Group VIII of the periodic table and a support containing an amorphous mesoporous alumina,
wherein said amorphous mesoporous alumina is prepared by a method comprising the following steps:
a) in a first alumina precipitation step a), precipitating alumina in an aqueous reaction medium containing at least one basic precursor selected from sodium aluminate, potassium aluminate, ammonia, sodium hydroxide and potassium hydroxide and at least one acid precursor selected from aluminum sulphate, aluminum chloride, aluminum nitrate, sulphuric acid, hydrochloric acid, and nitric acid, wherein at least one of the basic or acid precursors comprises aluminum, the relative flows of the acid and basic precursors is selected to obtain a pH of the reaction medium of between 8.5 and 10.5 and the flow of the acid and basic precursor(s) containing aluminum is adjusted to obtain a rate of progress of the first alumina precipitation step a) of between 45 and 90%, the rate of progress being defined as being the alumina formed as equivalent Al2O3 in said first alumina precipitation step a) as a proportion of the total quantity of alumina formed in the method, said first alumina precipitation step a) operating at a temperature of between 20 and 40° C., and for a period of between 2 minutes and 30 minutes, wherein said first alumina precipitation step a) produces a suspension,
aa) a first heating step wherein the suspension from step a) is heated at a temperature of between 20 and 90° C. for a period of between 7 and 45 minutes,
a?) in a second alumina precipitation step a?), precipitating alumina in an aqueous reaction medium containing at least one basic precursor selected from sodium aluminate, potassium aluminate, ammonia, sodium hydroxide and potassium hydroxide and at least one acid precursor selected from aluminum sulphate, aluminum chloride, aluminum nitrate, sulphuric acid, hydrochloric acid, and nitric acid, wherein at least one of the basic or acid precursors comprises aluminum, the relative flow of the acid and basic precursors is selected to obtain a pH of the reaction medium of between 8.5 and 10.5 and the flow of the acid and basic precursor(s) containing aluminum is adjusted to obtain a rate of progress of the second alumina precipitation step a?) of between 10 and 55%, the rate of progress being defined as being the alumina formed as equivalent Al2O3 in said second alumina precipitation step a?) as a proportion of the total quantity of alumina formed in the method, said step a?) operating at a temperature of between 40 and 90° C., and for a period of between 2 minutes and 30 minutes, wherein the step a?) produces a suspension,
a?a?) a second heating step wherein the suspension from step a?) is heated at a temperature of between 50 and 95° C.,
b) in a thermal treatment step, heating the suspension obtained in step a?a?) at a temperature of between 50 and 200° C. for a period of between 30 minutes and 5 hours,
c) in a filtration step, filtering the suspension obtained from thermal treatment step b) wherein an alumina gel is obtained, followed by at least one washing of the gel obtained,
d) in a drying step, drying the alumina gel obtained in step c) to obtain a powder,
e) in a shaping step, shaping the powder obtained in step d) to obtain a raw material, and
f) in a further thermal treatment step, heating the raw material obtained in step e) at a temperature of between 500 and 1000° C., in the presence or not of an air flow containing up to 60 vol. % of water.
US Pat. No. 10,392,571

CRYSTALLINE TRANSITION METAL MOLYBDOTUNGSTATE

UOP LLC, Des Plaines, IL...


US Pat. No. 10,390,521

PARKINSONS DISEASE MODEL AND METHODS

BOSTON MEDICAL CENTER COR...

9. A method of treating or preventing Parkinson's disease (PD)-related deficit(s) in a mammal, comprising expressing a sufficient amount of a functional caspase-3 cleavage-resistant PLA2g6 protein in neurons of the mammal to thereby treat or prevent Parkinson's disease (PD)-related deficit(s) in the mammal;wherein the functional caspase-3 cleavage-resistant PLA2g6 protein has an amino acid sequence at least 99% identical to SEQ ID NO: 1; and
wherein the functional caspase-3 cleavage-resistant PLA2g6 protein comprises a deletion or substitution of the aspartic acid residue at the amino acid position corresponding to amino acid position D183 of SEQ ID NO: 1.
US Pat. No. 10,392,315

PROPENE PRODUCTION METHOD

Braskem S.A., Camacari-B...

1. A process for producing propene from a mixture of alcohols obtained from at least one renewable source of carbon, comprising the following steps:a) Fermentation of at least one renewable source of carbon using a microorganism of the genus Clostridium for the production of a mixture of alcohols comprising ethanol, isopropanol and 1-butanol;
b) Separation of the alcohols from a fermentative wort to generate an aqueous solution containing ethanol, isopropanol and 1-butanol;
c) Dehydration of the alcohols to produce a mixture of olefins comprising ethene, propene and linear butenes, wherein the linear butenes comprise a mixture of 1-butene and 2-butenes (cis and trans isomers), water and by-products, comprising oxygenated compounds;
d) Removal of the water and by-products to generate a mixture of olefins comprising ethene, propene and linear butenes; and
e) Passing the mixture of olefins through an isomerization bed so that 1-butene is isomerized to 2-butenes and, subsequently, passing the mixture of olefins comprising ethene, propene and 2-butene through a metathesis bed, for a reaction between ethene and 2-butenes, to generate additional propene, wherein a molar ratio of ethene:linear butenes is corrected to be between 1:1 and 1.3:1; by means of one of the alternatives selected from the group consisting of:
(i) Addition of a stream containing ethanol to the process in step (c);
(ii) Addition of a stream containing ethene to the process in step (e); and
(iii) Addition of a stream containing ethanol to the process in step (c) and a stream containing ethene in step (e); wherein the process exhibits a yield in carbon moles higher than 90% propene with respect to the alcohols produced in step (a), wherein the microorganism is selected from the group consisting of Clostridium beijerinckii, Clostridium acetobutylicum, Clostridium butylicum, Clostridium aurantibutyricum, Clostridium tyrobutyricum and Clostridium saccarobutylicum; and wherein the propene produced exhibits 75 to 100% by mole of carbon of renewable origin.
US Pat. No. 10,390,522

NON-HUMAN ANIMALS HAVING A HUMANIZED PROGRAMMED CELL DEATH 1 GENE

REGENERON PHARMACEUTICALS...

1. A mouse whose genome comprises a humanized Programmed cell death 1 (Pdcd1) gene at an endogenous Pdcd1 locus,wherein the humanized Pdcd1 gene comprises exon 2, and comprises exon 3 in whole or in part, of a human Pdcd1 gene,
wherein the humanized Pdcd1 gene is operably linked to a Pdcd1 promoter and expresses a humanized Programmed cell death 1 (PD-1) polypeptide on the surface of activated T cells in the mouse, and
wherein the humanized PD-1 polypeptide comprises the N-terminal immunoglobulin V domain of a human PD-1 polypeptide and the intracellular domain of an endogenous mouse PD-1 polypeptide.
US Pat. No. 10,392,573

METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS

Ecolab USA Inc., St. Pau...

1. A method of inhibiting hydrates in a fluid comprising water, gas and optionally liquid hydrocarbon comprising treating the fluid with an effective hydrate-inhibiting amount of an inhibitor composition comprising a polymer prepared by polymerizing one or more N-alkyl (alkyl)acrylamide monomers in a solvent comprising one or more glycol ether solvents of formula CH3—(CH2)m—(O—CH2—CH2)n—OH where m is an integer of 0-1, and n is an integer from 1 to 4, wherein the solvent modifies at least one end group of the polymer and wherein said polymer has a distribution of molecular weights with about 60-100 percent in the range of 1,000 to 20,000 Dalton and about 0-25 percent in the range from 20,000 to 6,000,000 Dalton, has the property of maintaining a hold time of four hours or greater in a high pressure rocking cell test using test conditions of 1600 psi, an initial temperature of 25° C., a final temperature of 6° C., and a temperature ramp down time of less than two hours and a test fluid containing 25% oil, 72% water, 2.5% gas, and 0.5% sodium chloride, and achieves a solubility in aqueous solution of less than 200 nephelometric turbidity units (NTU).
US Pat. No. 10,392,318

MODIFIED COMPOSITE MOLECULAR SIEVE AND PREPARATION METHOD THEREOF, AND PARAFFIN ISOMERIZATION CATALYST

FUSHUN RESEARCH INSTITUTE...

1. A modified composite molecular sieve, comprising:SiO2 and a composite molecular sieve that comprises molecular sieve MCM-22 and a crystalline molecular sieve selected from at least one of ZSM-22, ZSM-23 and ZSM-48, wherein, the molecular sieve MCM-22 covers around the crystalline molecular sieve, and the SiO2 is loaded on the composite molecular sieve.
US Pat. No. 10,396,416

PASSIVE INSULATION MATERIALS

Thermal Ceramics, Inc., ...

1. An energy storage device housing for an energy storage device, comprising(a) a plurality of electrical cells;
(b) a material for limiting thermal runaway in the device, the cells having an upper normal operating temperature and a higher threshold temperature above which the cells are liable to thermal runaway, the material comprising a ceramic matrix that incorporates an inorganic gas-generating endothermic material, and in which:
the ceramic matrix is capable of providing thermal insulation properties at and above the upper normal operating temperature;
the gas-generating endothermic material is selected to undergo one or more endothermic reactions between the upper normal operating temperature and the higher threshold temperature;
one or more of said reactions results in the evolution of gases;
the ceramic matrix has sufficient porosity to permit said gases to vent from the material and thereby remove heat from the material; and
(c) a venting system forcibly openable by the generation of the gases, wherein the venting system forms part of the housing, with evolution of gases from an incident cell being releasable through the vent so as to prevent neighboring cells from reaching a critical ignition temperature,
wherein the material for limiting thermal runaway in the device comprises a formulation of:
Ceramic Oxide: 0-60 wt %
Opacifier: 0-30 wt %
Endothermic material: 10-90 wt %
Dry Binder: 0-10 wt %
Liquid Binder: 0-60 wt %
Fibre: 0-60 wt %
with the above formulation amounting to greater than 60%, greater than 70%, greater than 80%, or greater than 90% of the composition.
US Pat. No. 10,392,319

PROPANE DEHYDROGENATION SULFUR MANAGEMENT

Dow Global Technologies L...

1. A method for reducing sulfur present as sulfur or sulfur compounds in a hydrocarbon feedstream while effecting dehydrogenation of the hydrocarbon contained in the hydrocarbon feedstream, the method comprising:contacting the hydrocarbon feedstream with a fluidizable catalyst at a catalyst to hydrocarbon feed ratio in a range of from 1 to 100 under conditions sufficient to effect both removal from the hydrocarbon feedstream of at least a portion of the sulfur or sulfur compounds contained in the hydrocarbon feedstream and dehydrogenation of the hydrocarbon to yield a desulfurized crude olefin product, wherein:
a residence time of the fluidizable catalyst in contact with the hydrocarbon feedstream is from 0.1 minutes to 10 minutes;
the fluidizable catalyst is both a desulfurant and a dehydrogenation catalyst and comprises gallium in an amount within a range of from greater than 0 percent by weight to 5 percent by weight, and platinum in an amount within a range of from greater than 1 to 300 parts by weight per million parts by weight of the fluidizable catalyst on an alumina or alumina-silica catalyst support;
an amount of sulfur or sulfur compounds in the hydrocarbon feedstream prior to contact with the fluidizable catalyst is within a range of from at least 1 part by weight per million parts by weight of the hydrocarbon feedstream to less than 1000 parts by weight per million parts by weight of the hydrocarbon feedstream; and
the desulfurized crude olefin product comprises a reduced amount of sulfur or sulfur compounds relative to the sulfur or sulfur compounds present in the hydrocarbon feedstream prior to contact with the fluidizable catalyst, wherein the reduced amount of sulfur or sulfur compounds is less than 50 percent of the amount of sulfur or sulfur compounds in the hydrocarbon feedstream prior to contact with the fluidizable catalyst;
separating the desulfurized crude olefin product from the fluidizable catalyst onto which at least a portion of the sulfur or sulfur compounds is absorbed;
regenerating at least a portion of the fluidizable catalyst in a combustion portion of a regenerator, wherein the combustion portion comprises an upflow reactor with a net upward flow of fluidized catalyst and gases or counterflow configuration with a net upward flow of air and fuel and downward flow of fluidized catalyst; and
treating the fluidizable catalyst with an oxygen-containing gas for at least 2 minutes.
US Pat. No. 10,391,038

TOOTH SEALANT

Colgate-Palmolive Company...

1. A dental sealant composition comprising a basic amino acid in free or salt form (BAA) and fluoride ion source, wherein said fluoride ion source is present at a concentration of at least 12%, by weight, of the composition and is selected from stannous fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, aluminum fluoride, sodium hydrogen fluoride, sodium fluoride, calcium fluoride, magnesium fluoride, and potassium fluoride, wherein the composition is adapted for incorporation into a dental material and said dental material is selected from the group consisting of a dental amalgam, a fissure sealant resin, a composite bonding material, an orthodontic appliance, a dental prosthetic, a resin varnish, and an oral surgery implant, andwherein the composition has a daily dissolution rate of from about 0.1 to about 0.5%.
US Pat. No. 10,392,320

PREPARATION OF ALKYLAROMATIC COMPOUNDS

Rutgers, The State Univer...

1. A method of preparing p-xylene, comprising converting 3-methyleneheptane to p-xylene wherein the 3-methyleneheptane is contacted with an iridium catalyst.
US Pat. No. 10,392,577

COMPOSITION AND METHOD OF MANUFACTURING OVERBASED SULFONATE MODIFIED LITHIUM CARBOXYLATE GREASE

NCH CORPORATION, Irving,...

1. A method for making a lithium carboxylate grease comprising the steps of:adding and mixing an overbased calcium sulfonate or an overbased magnesium sulfonate or both with a base oil, lithium hydroxide, and water;
wherein the lithium carboxylate grease is a simple grease or a complex grease.
US Pat. No. 10,394,113

REFLECTIVE MASK BLANK, REFLECTIVE MASK AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE

HOYA CORPORATION, Tokyo ...

1. A reflective mask blank comprising:a multilayer reflective film; and
a phase shift film that shifts the phase of EUV light formed in that order on a substrate; wherein,
root mean square roughness (Rms), obtained by measuring a 1 ?m×1 ?m region on the surface of the phase shift film with an atomic force microscope, is not more than 0.50 nm, and power spectrum density at a spatial frequency of 10 to 100 ?m?1 is not more than 17 nm4.
US Pat. No. 10,391,039

AL2O3-FREE LITHIUM SILICATE GLASS COMPOSITION

SHOFU INC., Kyoto (JP)

1. An Al2O3-free dental lithium silicate glass composition consisting of the following components:SiO2: 60.0 to 80.0% by weight,
Li2O: 10.0 to 17.0% by weight,
K2O: 0.5 to 10.0% by weight,
ZrO2: 0.1 to 5.0% by weight,
a nucleating agent: 1.0 to 6.0% by weight,
a glass stabilizer: 0.0 to 8.0% by weight, and,
a colorant: 0.0 to 10.0% by weight
wherein the nucleating agent is one or more selected from the group consisting of P2O5, TiO2, WO3, V2O5, Pt and Ag,
wherein the glass stabilizer is one or more selected from the group consisting of CaO, MgO, SrO, BaO, ZnO, Y2O3, Ta2O5, Sb2O3, GeO2 and B2O3, and
wherein the colorant is one or more selected from the group consisting of MnO, Fe2O3, Tb4O7, Eu2O3, Ni2O3, Co2O3, Cr2O3, SnO2, CeO2, Nd2O3, Pr6O11, Sm2O3, V2O5, Dy2O3, Ho2O3 and Er2O3.
US Pat. No. 10,390,528

SOLID AGROFORMULATIONS FOR PREPARING NEAR MICRO-EMULSION AQUEOUS PESTICIDES

BASF Corporation, Florha...

1. A process for preparing an extruded pesticide granule comprising introducing urea into water to wet the urea, introducing a substantially water soluble pesticide active agent into the wetted urea, adding a nonionic surfactant to produce a damp mixture, extruding the damp mixture to form an extrudate, and drying the extrudate to form the extruded pesticide granule, wherein the substantially water soluble pesticide active agent has a water solubility of at least 10 g/L.
US Pat. No. 10,391,040

ORTHODONTIC MATERIAL, DEVICE AND METHODS OF PRODUCING THE SAME

ORVANCE, LLC, Caledonia,...

1. A composition configured for use in a buccal cavity of a mammal comprising:a composite material that is safe for use in the buccal cavity of the mammal comprising a moisture activated adhesive and a plasticizer at least substantially uniformly dispersed throughout an uncured, uncrosslinked high consistency rubber base material.
US Pat. No. 10,390,529

EMULSION BLOCKING LATEX PROTEIN AND OTHER SKIN IRRITANTS

1. A silver nanoparticle composition in water, comprising 10.0% stock solution, 1.0% of a copolymer of methyl vinyl ether/maleic anhydride, 0.5% eucalyptus oil, and 88.5% solution with silver nanoparticles (5 ppm); wherein the stock solution consists of:a. 88.2% water;
b. 0.35% sodium hydroxide;
c. 5.45% African palm vegetable oil;
d. 5.10% mixture of fatty acids of vegetable origin;
e. 0.42% Polyoxyethylene octyl phenyl ether;
f. 0.42% triethanol amine; and
g. 0.06% sodium benzoate.
US Pat. No. 10,391,041

SHEET-SHAPED HAIR COSMETIC AND HAIR TREATMENT METHOD AND SCALP-WIPING METHOD USING SAME

Kao Corporation, Tokyo (...

1. A method for treating hair with a sheet-like hair care product, the method comprising:dispensing the sheet-like hair care product from an access opening of a packaging container, thereby spreading out the sheet-like hair care product and retaining from 6 g to 25 g of a liquid cosmetic composition component (B) in the sheet-like hair care product, and then
contacting hair strands with the sheet-like hair care product,
wherein the sheet-like hair care product comprises:
(A) a substrate sheet having an area of from 50 cm2 to 1600 cm2, comprising cellulosic fibers, and having a bending resistance of 10 mm to 70 mm as measured by the 45° cantilever method in accordance with JIS L1096:2010 and
(B) a liquid cosmetic composition,
wherein said substrate sheet is impregnated with from 6 g to 25 g of said liquid cosmetic composition per sheet, in an amount of from 0.012 g to 0.037 g of said liquid cosmetic composition per cm2 of said substrate sheet,
wherein the substrate sheet has a mass before impregnation with the liquid cosmetic composition of from 0.5 g to 8.0 g,
wherein a proportion of the cellulosic fibers in the substrate sheet before impregnation with the liquid cosmetic composition is 30 mass % or more,
wherein the packaging container comprises the access opening, having an area of 25 mm2 to 4000 mm2, and an openable and closable lid covering the access opening, configured to seal contents of the packaging container,
and wherein the substrate sheet (A) impregnated with the liquid cosmetic composition (B) is in the packaging container prior to dispensing.
US Pat. No. 10,390,530

USE OF HYDROPHOBIC, SELF-EMULSIFYING POLYGLYCEROL ESTERS AS ADJUVANTS AND ANTI-SPRAY-DRIFT AGENTS

Evonik Degussa GmbH, Ess...

1. A self-emulsifying composition, comprising:at least one hydrophobic, at least partially water-insoluble polyglycerol ester in combination with at least one emulsifier,
wherein the at least one hydrophobic, at least partially water-insoluble polyglycerol ester has an HLB value of 8 or less and is of Formula 2:
MaDbTc  Formula 2
wherein
M=[C3H5(OR)2O1/2],
D=[C3H5(OR)1O2/2],
T=[C3H5O3/2],
a=1 to 10,
b=0 to 10,
c=0 to 3,
wherein the sum total of a+b+c is 1 to 20,
wherein the radicals R independently of one another are identical or different radicals of the formula R?—C(O)— or H,
wherein R? is a monovalent aliphatic, saturated or unsaturated hydrocarbon radical having 3 to 39 C atoms,
wherein at least one radical R corresponds to a radical of the formula R?—C(O)—, and
wherein the acyl radicals are fatty acid mixtures comprising at least 70% by weight of oleic acid.
US Pat. No. 10,394,117

PELLICLE FILM INCLUDING GRAPHITE-CONTAINING THIN FILM FOR EXTREME ULTRAVIOLET LITHOGRAPHY

Samsung Electronics Co., ...

1. A method of manufacturing a pellicle film, the method comprising:placing a nickel foil in a heating container;
heat-treating the nickel foil during a first time period at a first temperature;
heat-treating the nickel foil during a second time period at a second temperature;
cooling the nickel foil at a third temperature;
separate from the nickel foil a graphite film grown on a surface of the nickel foil, by etching the nickel foil using a first solution;
removing impurities from the graphite film using a second solution and/or water; and
placing the graphite film on a frame to form the pellicle film.
US Pat. No. 10,397,705

MULTI-LAYER COMPOSITE FOR ACOUSTIC MEMBRANES

TESA SE, Norderstedt (DE...

1. A multi-layer composite adapted as a membrane for electroacoustic transducers, the multi-layer composite comprising: comprisesat least one first outer layer and at least one second outer layer, wherein the at least one first outer layer and the at least one second outer layer consist of a polyphenylene sulfide plastic having a halogen content that does not exceed 550 ppm; and
a damping layer disposed between the at least one first outer layer and the at least one second outer layer, wherein the damping layer consists of an acrylate pressure-sensitive adhesive layer or a silicone pressure-sensitive adhesive layer,
wherein the at least one first outer layer and the at least one second outer layer have a thickness from 1 to 50 ?m.
US Pat. No. 10,394,118

PHOTOMASK AND METHODS FOR MANUFACTURING AND CORRECTING PHOTOMASK

DAI NIPPON PRINTING CO., ...

1. A photomask using an ArF excimer laser as an exposing source, being used for a projection exposure by an off axis illumination, and comprising on a principal plane of a transparent substrate a main pattern transferred to a transfer-target surface by the projection exposure and an assist pattern formed nearby the main pattern and not transferred to the transfer-target surface;wherein the main pattern and the assist pattern are each constituted from a semi-transparent film made of a same material; and
a retardation of 180° is generated between a light transmitting through the main pattern and a light transmitting through a transparent region of the transparent substrate, and a predetermined retardation within a scope of 70° to 115° is generated between a light transmitting through the assist pattern and the light transmitting through the transparent region of the transparent substrate.
US Pat. No. 10,390,532

INSECTICIDE COMPOSITION INCLUDING THIAMETHOXAM AND A SYNERGISTIC AGENT

1. Insecticide composition comprising:an active ingredient that includes the combination of
thiamethoxam as synthetic insecticidal molecule, and
at least one synergistic agent selected from the group consisting of N,N-diethyl-3-methylbenzamide (DEET) at a concentration comprised between 3.10?8 M and 3.10?7 M in the composition, 3-[N-Butyl-N-acetyl]-aminopropionic acid ethyl ester (IR3535®) at a concentration comprised between 3.10?9 M and 3.10?8 M in the composition, and a mixture thereof and present in the composition at a ratio of 0.001 and 0.2 between a molar amount of said synergistic agent to a molar amount of thiamethoxam.
US Pat. No. 10,392,583

CLEANING COMPOSITION WITH A HYDROPHILIC POLYMER HAVING HIGH SELF-ADHESION AND PROVIDING RESIDUAL BENEFITS

1. A cleaning composition comprising:about 15 to 35 wt. % ethoxylated alcohol surfactant, which can serve all or in part as an adhesion promoter; wherein at least a portion of the ethoxylated alcohol surfactant comprises a polyethoxy residual having 25 to 45 ethoxy groups;
a second surfactant component, which is a second nonionic surfactant, a cationic surfactant or a combination thereof;
greater than 0 to about 3.5 wt. % of a non-polar hydrocarbon;
at least about 40 wt. % water; and a hydrophilic polymer, which comprises a copolymer and/or terpolymer including (a) a monomer having a quaternary ammonium function, (b) an acrylic acid monomer copolymerizable with (a), and (c) optionally a hydrophilic monomer copolymerizable with both (a) and (b);
wherein the composition is a self-adhesive gel having a gel temperature of about 50 to about 80° C.
US Pat. No. 10,390,533

SURFACES WITH OLIGOMERIC OR POLYMERIC ANTIMICROBIALS

ORTHOBOND CORPORATION, N...

1. An article comprising:a surface having an antimicrobial layer disposed thereon, the antimicrobial layer comprising:
an organophosphorus layer and antimicrobial oligomers or polymers bonded to the organophosphorus layer,
wherein the surface comprises a metal selected from a group consisting of titanium, a titanium alloy, stainless steel, a cobalt chrome alloy, nickel, molybdenum, tantalum, zirconium, magnesium, and an alloy containing at least one of nickel, molybdenum, tantalum, zirconium and magnesium,
wherein the antimicrobial oligomers or polymers comprise about 3 to about 50,000 repeating antimicrobial monomer units, and
wherein the antimicrobial monomer units comprise ammonium salts or pyridinium salts.
US Pat. No. 10,392,327

METHYL FLUORIDE PRODUCTION METHOD

DAIKIN INDUSTRIES, LTD., ...

1. A method for producing methyl fluoride, comprising the steps of:(1) pyrolyzing 1,1,3,3,3-pentafluoro-2-trifluoromethylpropyl methyl ether in a gas phase to thereby obtain a mixed gas containing methyl fluoride and acid fluoride; and
(2) rectifying the mixed gas obtained in step (1) to thereby obtain methyl fluoride,
wherein in step (2), the mixed gas obtained in step (1) is supplied to a rectification column, and the supply of the mixed gas is conducted at a pressure exceeding atmospheric pressure.
US Pat. No. 10,392,584

DETERGENT COMPOSITION COMPRISING A POLYMER THAT PERFORMS BOTH A CLEANING AND RINSING FUNCTION

Ecolab USA Inc., Saint P...

1. An alkaline liquid detergent and rinsing composition comprising: from about 40 wt. % to about 85 wt % of an alkalinity source;at least two nonionic surfactants, wherein the nonionic surfactants comprise from about 0.1 wt. % to about 10 wt. % of a C8-C18 alcohol alkoxylate with about 10 to about 30 moles of ethylene oxide and from about 1 wt % to about 10 wt. % of a EO/PO copolymer, wherein the EO/PO copolymer does not contain any other alkyl groups; and an EO/PO copolymer, wherein the alcohol alkoxylate is in an amount of from about 1 wt. % to about 10 wt. %, and wherein the EO/PO copolymer and alcohol alkoxylate are in a ratio of between about 3:1 to 1:3;
from about 10 wt. % to about 35 wt % of a builder;
from about 1 wt. % to about 40 wt. % of a polymer comprising a polycarboxylic acid polymer, copolymer, and/or terpolymer, wherein said polycarboxylic acid polymer, copolymer, and/or terpolymer is an acrylic/maleic acid copolymer;
wherein said composition is free of a fatty acid or salt thereof; and
wherein said composition performs both a cleaning and rinsing function.
US Pat. No. 10,390,534

COMPOSITIONS AND METHODS FOR MODULATING PLANT PARASITIC NEMATODES

Marrone Bio Innovations, ...

1. A method for modulating soybean cyst nematode infestation of a plant comprising the steps of:contacting the plant, one or more seeds of the plant, and/or soil in which the plant is grown, with a composition comprising a fermented whole cell broth collected from
a bacterial strain of Flavobacterium sp. H492 (NRRL Accession No. B-50584), in an amount effective to modulate the soybean cyst nematode infestation.
US Pat. No. 10,391,046

PERSONAL CARE COMPOSITIONS

Colgate-Palmolive Company...

1. A personal care composition comprising:a surfactant system consisting essentially of:
an anionic surfactant;
a zwitterionic or amphoteric surfactant; and optionally
a non-ionic surfactant;
a preservative system;
a pH modifier;
optionally a moisturizer or a skin conditioner or both a moisturizer and a skin conditioner; and
a viscosity adjusting system,
wherein the viscosity adjusting system comprises glyceryl oleate and at least one additional viscosity adjusting agent selected from a mixture of PEG-120 methyl glucose trioleate and propylene glycol, and
wherein the ingredients are homogenously dispersed.
US Pat. No. 10,392,328

LOW-CARBON ENVIRONMENTALLY-FRIENDLY FOAMER COMPOSITION

Zhejiang Quhua Fluor-Chem...


US Pat. No. 10,392,585

AUTOMATIC DISHWASHING DETERGENT

Rohm and Haas Company, P...

1. An automatic dishwashing detergent composition comprising:aspartic acid diacetic acid or salt thereof;
a builder; and
a surfactant;
a dispersant polymer with a Mw from 2000 to 100,000, wherein the dispersant polymer is selected from the group consisting of a homopolymer of (meth)acrylic acid, a copolymer consisting of methacrylic acid and acrylic acid, a copolymer consisting of (meth)acrylic acid and at least one ethylenically unsaturated monomer, salts thereof and mixtures thereof;
wherein the at least one ethylenically unsaturated monomer is selected from the group consisting of ethyl acrylate, butyl acrylate, styrene, 2-acrylamido-2-methylpropane sulfonic acid, 2-(meth)acrylamido-2-methylpropane sulfonic acid, 4-styrenesulfonic acid, vinylsulfonic acid, 3-allyloxy-2-hydroxy-1-propane sulfonic acid, 2-sulfoethyl(meth)acrylic acid, 2-sulfopropyl(meth)acrylic acid, 3-sulfopropyl(meth)acrylic acid, 4-sulfobutyl(meth)acrylic acid, salts thereof and mixtures thereof.
US Pat. No. 10,394,121

PATTERN-FORMING METHOD AND COMPOSITION

JSR CORPORATION, Minato-...

1. A composition comprising a smaller molecular weight polymer and a larger molecular weight polymer, each having a different weight average molecular weight,wherein the smaller molecular weight polymer and the larger molecular weight polymer are each a styrene polymer having a group which bonds to at least one end of a main chain of the smaller molecular weight polymer and the larger molecular weight polymer and which comprises at least one group selected from the group consisting of a hydroxy group, a carboxy group, a sulfanyl group, an epoxy group, a cyano group, a vinyl group and a carbonyl group,
a difference in weight average molecular weights between the smaller molecular weight polymer and the larger molecular weight polymer no less than 2,000.
US Pat. No. 10,390,535

BACILLUS THURINGIENSIS RTI545 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND CONTROLLING PLANT PESTS

FMC Corporation, Philade...

1. A composition comprisinga biologically pure culture of Bacillus thuringiensis RTI545 deposited as ATCC No. PTA-122161, and
an agriculturally acceptable adjuvant, which improves the stability of the Bacillus thuringiensis RTI545;
for application to a plant for one or both of benefiting plant growth or conferring protection against a plant pest in a susceptible plant.
US Pat. No. 10,391,047

MOUTHRINSE FORMULATIONS COMPRISING FLUORIDE AND A METAL SALT OF PYRROLIDONE CARBOXYLIC ACID

Colgate-Palmolive Company...

1. An oral care composition comprising:(a) a metal salt of pyrrolidone carboxylic acid;
(b) at least one fluoride ion source; and
(c) at least one ?-hydroxy acid or salt thereof;
wherein the composition is a mouthwash or a mouthrinse.
US Pat. No. 10,392,586

AUTOMATIC DISHWASHING COMPOSITIONS HAVING A DETERGENT GRANULE

RECKITT BENCKISER FINISH ...

1. A method of automatic dishwashing in an automatic dishwashing machine, comprising:providing a monodose automatic dishwashing detergent composition housed within a rigid polyvinyl alcohol capsule having one or more compartments; and
washing at least one aluminum-comprising article in an automatic dishwashing machine using the monodose automatic dishwashing detergent composition, wherein corrosion of the aluminum by the monodose automatic dishwashing detergent composition is inhibited;
wherein the monodose automatic dishwashing detergent composition consists of:
at least one non-ionic surfactant;
sodium citrate;
a bleaching compound;
a source of alkalinity;
a binder;
enzymes;
a dye;
an antifoam agent;
a fragrance;
a bleach activator;
a bleach catalyst;
a sulfonated polymer; and
at least one granule comprising, within the same granule, silicate together with methylglycine diacetic acid;
wherein the granule comprises 70-90% by weight methylglycine diacetic acid and 5-11% by weight of silicate,
wherein the total amount of builder present in the monodose automatic dishwashing detergent composition is up to 60% by weight, and
wherein the bleaching compound is a percarbonate bleach.
US Pat. No. 10,390,536

METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND/OR ARACHNIDS

1. A method of repelling an insect and/or an arachnid, the method consisting essentially of applying a composition to an animal, a human, a substrate and/or a location, the composition consisting essentially of an isolated carvacrol compound and an isolated cumin compound;wherein the isolated carvacrol compound is carvacrol, thymol or a combination thereof and the isolated cumin compound is cumin alcohol, cuminic acid or combinations thereof,
wherein application of the composition to the animal, the human, the substrate and/or the location repels the insect and/or the arachnid from the animal, the human, the substrate and/or the location, and
wherein the insect and/or the arachnid is a mosquito, a sand fly or a tick.
US Pat. No. 10,391,048

RECOMBINANT HIGH-STABILITY SUPEROXIDE DISMUTASE AND APPLICATION THEREOF

Hangzhou Redox Pharmatech...

1. A superoxide dismutase comprising the amino acid sequence of SEQ ID NO:4.
US Pat. No. 10,392,330

PROCESS FOR PRODUCING DIISOPROPYL ETHER FROM HIGH PURITY PROPYLENE

UOP LLC, Des Plaines, IL...

1. A process for producing diisopropyl ether comprising:(a) reacting water and the propylene of a feedstock containing at least 99.9 mass-% propylene and the balance propane, to produce isopropyl alcohol and reacting the isopropyl alcohol with propylene to produce diisopropyl ether in a single reactor without an external diluent and in the presence of an acidic ion exchange resin catalyst at a temperature of from about 105° C. to about 133° C. to generate a reactor effluent comprising water, isopropyl alcohol, diisopropyl ether, propylene, propane and acid;
(b) treating the mixture in an acid removal zone to generate an acid-depleted mixture;
(c) recycling a portion of the acid-depleted mixture to the reactor, and passing a second portion of the acid-depleted mixture to a light ends fractionation column;
(d) separating, in the light ends fractionation column, an overhead stream comprising propane and propylene, and a bottoms stream comprising water, isopropyl alcohol, and diisopropyl ether;
(e) passing the overhead stream to the reactor until the concentration of propane is sufficient to operate as a diluent and then purging a portion of the overhead stream and passing the remainder of the overhead stream to the reactor; and
(f) passing the bottoms stream to a recovery zone to separate and collect the diisopropylether.
US Pat. No. 10,392,331

PROCESS FOR PRODUCING DIISOPROPYL ETHER FROM HIGH PURITY PROPYLENE

UOP LLC, Des Plaines, IL...

1. A process for producing diisopropyl ether comprising:(a) reacting water and the propylene of a feedstock containing at least 99.9 mass-% propylene to produce isopropyl alcohol and reacting the isopropyl alcohol with propylene to produce diisopropyl ether in a single reactor and in the presence of an acidic ion exchange resin catalyst and a C4 diluent at a temperature of from about 105° C. to about 133° C. to generate a reactor effluent comprising water, isopropyl alcohol, diisopropyl ether, propylene, C4 and acid;
(b) treating the mixture in an acid removal zone to generate an acid-depleted mixture;
(c) recycling a portion of the acid-depleted mixture to the reactor, and passing a second portion of the acid-depleted mixture to a light ends fractionation column;
(d) separating, in the light ends fractionation column, an overhead stream comprising propane and propylene, a side cut stream comprising C4, and a bottoms stream comprising water, isopropyl alcohol, and diisopropyl ether;
(e) purging a portion of the overhead stream and passing the remainder of the overhead stream to the reactor;
(f) passing the sidecut stream comprising C4 to the reactor; and
(g) passing the bottoms stream to a recovery zone to separate and collect the diisopropylether.
US Pat. No. 10,392,588

WATER-SOLUBLE UNIT DOSE ARTICLE COMPRISING A CYCLIC DIAMINE AND AN AMPHOTERIC SURFACTANT

1. A method of washing a fabric, the method comprising the steps of;a. providing a water-soluble unit dose article, the water-soluble unit dose article comprising a water-soluble film and a liquid laundry detergent composition, wherein the liquid laundry detergent composition comprises;
i) a non-soap anionic surfactant;
ii) an amphoteric surfactant; and
iii) a cyclic diamine, wherein the cyclic diamine is selected from the group consisting of 2-methylcyclohexane-1,3-diamine; 4-methylcyclohexane-1,3-diamine; and mixtures thereof;
b. adding the water-soluble unit dose article to sufficient water to dilute the liquid laundry detergent composition to create a wash liquor; and
c. contacting fabric to be washed with the wash liquor; wherein the article is used in an automatic fabric wash operation.
US Pat. No. 10,390,538

PROCESS FOR PREPARING A BAKED PRODUCT WITH ANTI-STALING AMYLASE AND PEPTIDASE

1. A process for preparing a baked product comprising:adding to either a flour that is used to form a dough or directly to a dough:
at least one maltogenic alpha-amylase in an amount of 0.1-10,000 MANU per kg of flour; and
at least one endopeptidase in an amount of about 0.01 mg/kg to about 10 mg/kg of flour, wherein the at least one endopeptidase is selected from the group consisting of an endopeptidase having at least 90% identity to SEQ ID NO: 9, an endopeptidase haying at least 90% identity to SEQ ID NO: 15, and combinations thereof; and
baking the dough to form the baked product, and wherein the added endopeptidase maintains springiness of the baked product for a period of at least 4-21 days after baking.
US Pat. No. 10,391,050

DERMATOLOGICAL, COSMETIC OR COSMECEUTICAL COMPOSITIONS INTENDED FOR SKIN TREATMENT

1. A dermatological, cosmetic, or cosmeceutical composition designed for skin care, the composition being in a form selected from a group consisting of hydrogel, o/w gel cream, w/o gel cream, o/w cream, w/o cream, w/s cream, and o/w/o cream, said composition comprising a gastropod spawn extract isolated from lysed spawn of the Helicidae family and which comprises organic and inorganic molecules, wherein:(i) the organic molecules comprise polysaccharides, proteins, peptides and amino acids;
(ii) the inorganic molecules comprise cations and anions derived from phosphorus, calcium, sodium, magnesium, iron, zinc, copper and selenium;
(iii) the gastropod spawn extract is in a concentration that activates and mobilizes skin stem cells and prevents the loss thereof that takes place as a consequence of chronological and premature aging;
(iv) the gastropod spawn extract has the characteristic electrophoretic fingerprint as shown in FIG. 1;
(v) the gastropod spawn extract has superoxide dismutase activity; and
(vi) the gastropod spawn extract is obtained by a process comprising:
(a) manually collecting the gastropod spawn and eliminating soil content by sieving;
(b) washing the gastropod spawn with distilled water, immersing the gastropod spawn in a saline solution and refrigerating the gastropod spawn at a temperature of between 2° C. and 8° C.;
(c) washing the gastropod spawn with purified water to remove the saline solution;
(d) suspending gastropod spawn at a concentration of between 40% and 70% by weight in purified water, a saline solution, or a component or combination of components of the dermatological, cosmetic, or cosmeceutical composition;
(e) homogenizing the suspended gastropod spawn with a grinder, a colloidal mill, or an in-line homogenizer to produce a gastropod spawn extract; and
(f) filtering the gastropod spawn extract through a 1-mm mesh to obtain a gastropod spawn extract.
US Pat. No. 10,392,589

METHOD FOR EXTRACTION AND DISSOLUTION OF HOP ACIDS IN AQUEOUS MEDIA

IFAST NV, Roosdaal (BE)

1. A method for preparing a brewed beverage, comprising:adding at least one type of complexes of hop acids, with at least one type of carbon-containing chemical substance(s), with at least one functional group containing a nitrogen atom with a lone electron pair and at least one other polar and/or hydrophilic functional group; wherein said adding is during the brewing process, wherein said adding is to a wort; and wherein said hop acids are selected from the group consisting of alpha-acids, oxidized alpha-acids, beta-acids, and oxidized beta-acids.
US Pat. No. 10,391,051

ORAL CARE COMPOSITION COMPRISING CUTTLEFISH BONE POWDER AND USES THEREOF

VISIONATUROLAB INC., Bla...

1. A method for preparing a demineralized cuttlefish bone powder, the method comprising:(a) grinding a cuttlefish bone to obtain a coarse cuttlefish bone powder;
(b) sieving the coarse bone powder to obtain a first cuttlefish bone powder having particle size from 60 microns to 61 microns;
(c) mildly demineralizing the first cuttlefish bone powder in a solution of ammonium chloride or ammonium acetate having a pH of about 4.5 to about 5.5, at a temperature and for a period of time sufficient to obtain a demineralized cuttlefish bone powder having more than 95% (w/w) calcium carbonate content;
(d) washing the demineralized cuttlefish bone powder until a neutral pH is reached; and
(e) drying the demineralized cuttlefish bone powder.
US Pat. No. 10,392,333

METHOD OF PRODUCING FORMALDEHYDE FROM METHANOL

Purdue Research Foundatio...

1. A method for producing formaldehyde from methanol, the method comprising:packing a catalyst comprising platinum, bismuth and a support material into a reactor;
introducing a reactant mixture containing methanol into the reactor such that the reactant mixture containing methanol is in close contact with the catalyst; and
heating the reactant mixture containing methanol to a temperature for a period of time.
US Pat. No. 10,392,590

METHOD AND SYSTEM FOR DISTILLING ALCOHOL IN AN ALCOHOL PRODUCTION PROCESS

Fluid Quip Process Techno...

1. A method for distilling alcohol in an alcohol production process, the method comprising:fermenting a mixture of water and milled grain to produce alcohol-laden beer;
distilling the alcohol-laden beer in a beer column maintained at a subatmospheric pressure to produce a vapor, primarily including alcohol, and whole stillage, which includes stillage;
evaporating water from all or a portion of the stillage via one or more evaporators;
generating steam from a fluid via one or more steam generators, which do not receive the stillage; and
using at least a portion of the generated steam from the one or more steam generators to supply sufficient heat to the beer column for distilling the alcohol-laden beer to produce alcohol.
US Pat. No. 10,391,052

INJECTION PREPARATION AND METHOD FOR PRODUCING THE SAME

FUJIFILM CORPORATION, To...

1. An injection preparation comprising:an aqueous composition containing the following (i), (ii), (iii), and (iv); and
a container which seals the aqueous composition,
wherein a concentration of oxygen in gas within the container which seals the aqueous composition is less than or equal to 1.5 volume %:
(i) pemetrexed or a salt thereof;
(ii) at least one antioxidant agent A which is selected from the group consisting of cysteine and a salt thereof, and of which the content is 0.001 mass % to 0.1 mass % with respect to the total mass of the aqueous composition;
(iii) thioglycerol of which the content is 0.001 mass % to 0.1 mass % with respect to the total mass of the aqueous composition, wherein a ratio of the content of thioglycerol to the content of pemetrexed or a salt thereof in the aqueous composition is 1:0.007 to 1:0.031 on a mass basis; and
(iv) an aqueous solvent of which the content is greater than or equal to 50 mass % with respect to the total mass of the aqueous composition,
wherein a ratio of the content of thioglycerol to the content of the antioxidant agent A in the aqueous composition is 1:0.3 to 1:6.5 on a mass basis, and
wherein the pH of the aqueous composition is 7.0 to 9.0.
US Pat. No. 10,392,334

METHOD FOR PRODUCING KETONE AND/OR ALCOHOL, AND SYSTEM THEREOF

UBE INDUSTRIES, LTD., Ub...

1. A method for producing a ketone and/or alcohol by decomposing a hydroperoxide and an ester compound in an oxidation reaction solution obtained from oxidizing a hydrocarbon compound with molecular oxygen, in which the ketone and/or alcohol has the same number of carbon atoms as the hydrocarbon compound; wherein the method comprises:neutralizing at least a part of a carboxylic acid in the oxidation reaction solution by contacting the oxidation reaction solution with a first alkaline solution comprising a carbonate of an alkali metal, and separating the reaction mixture into a first oil phase and a first water phase, wherein a content of the hydroperoxide in the first oil phase is more than 90% of a content of the hydroperoxide in the oxidation reaction solution, and a pH of the first water phase is 8.5 or more and 9.55 or less;
decomposing the hydroperoxide and the ester compound in the first oil phase by contacting the first oil phase with a second alkaline solution having a higher pH value than the first alkaline solution, and separating the reaction mixture into a second oil phase and a second water phase, wherein a pH of the second water phase is greater than or equal to the pKa of the hydroperoxide and 14.0 or less;
recovering at least a part of an unreacted hydrocarbon from the second oil phase;
obtaining the ketone and/or alcohol from the second oil phase after recovering at least a part of the unreacted hydrocarbon by purification;
recycling a part or all of the second water phase as a part of the first alkaline solution; and
recovering the carbonate of an alkali metal from the first water phase and recycling the carbonate of an alkali metal to the first alkaline solution.
US Pat. No. 10,390,541

METHODS FOR MAKING SHELF-STABLE CULTURED DAIRY PRODUCTS

fairlife, LLC, Chicago, ...

1. A process to produce a cultured dairy product, the process comprising:(a) subjecting a milk product comprising from about 1 to about 1.9 wt. % milk sugar to ultra-high temperature (UHT) sterilization to form a sterilized milk product;
(b) cooling the sterilized milk product to a temperature less than or equal to about 50° C. to form a sterilized reduced sugar milk base;
(c) contacting the milk base with a lactic acid bacteria culture and aseptically packaging in a container, wherein the lactic acid bacteria culture comprises Lactobacillus bulgaricus, Streptococcus thermophilus, Lactobacillus acidophillus, Lactobacillus casei, Lactococcus lactis, Lactococcus cremoris, Latobacillus plantarum, Bifidobacterium, Leuconostoc, or any combination thereof; and
(d) storing under conditions sufficient to reduce the pH of the contents in the container to less than about 4.7 to produce the cultured dairy product;
wherein the cultured dairy product contains from about 10,000,000 cfu/g to about 3,000,000,000 cfu/g of live bacteria or live active cultures.
US Pat. No. 10,391,053

METHODS OF INTRAVENOUS ADMINISTRATION OF GLYBURIDE

Biogen Chesapeake LLC, C...

1. A method for achieving a less than 10% reduction of the concentration of glyburide solutions placed in a container, tube, and/or filter of polyvinyl chloride (PVC), comprising contacting said PVC container, tube, and/or filter with a glyburide flushing solution, wherein said glyburide flushing solution has a glyburide concentration of at least 2 ?g/mL of glyburide, flushing said glyburide flushing solution out of said PVC container, tube, and/or filter, and, after said flushing, refilling said PVC container, tube, and/or filter with a therapeutic glyburide solution, thereby reducing adsorption of the therapeutic glyburide solution to said PVC container, tube, and/or filter such that a less than 10% reduction in concentration of the therapeutic glyburide solution is achieved in said PVC container, tube, and/or filter.
US Pat. No. 10,390,542

DAIRY COMPOSITIONS AND METHOD OF MAKING

fairlife, LLC, Chicago, ...

1. A method for producing a dairy product, the method comprising:separating milk to produce butter fat and skim milk;
ultrafiltrating the skim milk to produce a UF permeate and a UF retentate;
nanofiltrating the UF permeate to produce a NF permeate and a NF retentate;
reverse osmosis of the NF permeate to produce a RO permeate and a RO retentate;
combining the butter fat with the UF retentate, RO retentate, and at least one of water and the RO permeate to produce a dairy product; and
wherein the dairy product comprises from 1 to 3 wt. % butter fat, from 2.5 to 5.5 wt. % protein, from 0.5 to 1 wt. % minerals, and from 1 to 3 wt. % lactose.
US Pat. No. 10,391,054

PHARMACEUTICAL TABLET FOR USE IN ADMINISTERING NICOTINE

1. A tablet for use in administering nicotine, comprising:a chewable polymer system;
nicotine;
the nicotine being used as a non-smoking agent;
a flavor; and
a sweetener;
wherein the polymer system comprises vinyl polymers in an amount of at least 70% by weight of the polymer system; and
wherein the vinyl polymers are a combination of polyvinyl acetate polymer (PVAc) and vinyl laurate/vinyl acetate copolymer (VL/VA).
US Pat. No. 10,392,336

FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES

Chevron Phillips Chemical...

1. A process for forming an ?,?-unsaturated carboxylic acid or salt thereof, the process comprising(1) contacting
(a) a metalalactone compound comprising a Group 8-10 metal;
(b) a diluent; and
(c) an anionic polyaromatic resin with associated metal cations to provide a reaction mixture;
(2) applying conditions to the reaction mixture suitable to induce a metalalactone elimination reaction to form the ?,?-unsaturated carboxylic acid or a salt thereof and a polyaromatic resin; and
(3) regenerating the anionic polyaromatic resin by contacting the polyaromatic resin with a base comprising a metal cation following the formation of the ?,?-unsaturated carboxylic acid or the salt thereof.
US Pat. No. 10,391,055

CARRIER-ANTIBODY COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME

Mayo Foundation for Medic...

1. A lyophilized composition comprising nanoparticle complexes having an outside surface, wherein each of the nanoparticle complexes comprises:a) albumin;
b) antibodies having a human epidermal growth factor receptor (HER) binding portion; and
c) paclitaxel;said nanoparticle complexes being lyophilized, and wherein upon reconstitution with an aqueous solution, the HER binding portion of said antibodies are arranged on the outside surface of the nanoparticle complexes and are capable of binding to HER in vivo.
US Pat. No. 10,391,056

PHARMACEUTICAL COMPOSITIONS OF HYDROPHOBIC CAMPTOTHECIN DERIVATIVES

Taiwan Lipsome Company, L...

1. A pharmaceutical composition, comprising:at least one hydrophobic camptothecin derivative or a pharmaceutically acceptable salt of said derivative; and
at least one polyethylene glycol (PEG) conjugated phospholipid;
wherein the molar ratio of said PEG conjugated phospholipid to said hydrophobic camptothecin derivative or said pharmaceutically acceptable salt of said hydrophobic camptothecin derivative is about 0.45:1 to about 1.05:1; and said hydrophobic camptothecin derivative is a compound selected from the group consisting of: TLC388HCl; TLC1988HCl; and mixtures thereof.
US Pat. No. 10,392,595

VASCULARIZED IN VITRO PERFUSION DEVICES, METHODS OF FABRICATING, AND APPLICATIONS THEREOF

Advanced Solutions Life S...

1. A vascularized in vitro perfusion device comprising an adaptable microcirculation, said device comprising:a supporting structure comprising a gel matrix,
a fabricated network of microfluidic endothelial cell-lined channels, said fabricated network comprising an inlet channel, an outlet channel, and at least one cross channel connecting the inlet channel to the outlet channel, said cross channel positioned at least partially within the gel matrix,
an inlet port in fluid communication with the fabricated network, and an outlet port in fluid communication with the fabricated network, and
a neovasculature, said neovasculature being derived from intact native microvessels incorporated into the gel matrix and subject to maturing conditions comprising endothelial sprouting and an inosculation between at least two endothelial sprouts respectively derived from the at least one cross channel of the fabricated network and the neovasculature to form a lumen connection therebetween, said neovasculature thus in lumen continuity with said at least one cross channel through the inosculation,wherein the fabricated network is in vascular communication and lumen continuity with the neovasculature to form an adaptable microcirculation.
US Pat. No. 10,392,597

TEXTURIZING LACTIC ACID BACTERIA STRAINS

1. A texturizing lactic acid bacteria strain selected from the group consisting of:(a) the D-cycloserine resistant Lactobacillus delbrueckii subsp bulgaricus strain CHCC12944 deposited with the Deutsche Sammlung von Mikroorganismen and Zellkulturen (DSMZ) under accession number DSM 24019 and mutant strains derived therefrom that are resistant to D-cycloserine and produce the same or more texture as the deposited strain as determined by shear stress and/or gel stiffness when inoculated into fermented milk in the same amount of at least 104 cells/ml as the deposited strain;
(b) the D-cycloserine resistant Lactobacillus delbrueckii subsp bulgaricus strain CHCC12945 deposited with the DSMZ under accession number DSM 24020 and mutant strains derived therefrom that are resistant to D-cycloserine and produce the same or more texture as the deposited strain as determined by shear stress and/or gel stiffness when inoculated into fermented milk in the same amount of at least 104 cells/ml as the deposited strain;
(c) the D-cycloserine resistant Streptococcus thermophilus strain CHCC13235 that was deposited with the DSMZ under accession number DSM 24010 and mutant strains derived therefrom that are resistant to D-cycloserine and produce the same or more texture as the deposited strain as determined by shear stress and/or gel stiffness when inoculated into fermented milk in the same amount of at least 104 cells/ml as the deposited strain; and
(d) the D-cycloserine resistant Streptococcus thermophilus strain CHCC13236 deposited with the DSMZ under accession number DSM 24011 and mutant strains derived therefrom that are resistant to D-cycloserine and produce the same or more texture as the deposited strain as determined by shear stress and/or gel stiffness when inoculated into fermented milk in the same amount of at least 104 cells/ml as the deposited strain.
US Pat. No. 10,390,547

HARD CANDY WITH REDUCED SUGAR

WM. WRIGLEY JR. COMPANY, ...

1. A hard candy composition, comprising:a) a bulking sweetener agent, consisting of isomaltulose, erythritol or combinations thereof; and
b) a doctoring agent, consisting of inulin;
wherein the bulking sweetener agent to doctoring agent ratio is 70/30 to 40/60 dry solids wt. %.
US Pat. No. 10,391,059

ORAL RAPAMYCIN NANOPARTICLE PREPARATIONS AND USE

Rapamycin Holdings, Inc.,...

1. A method of orally administering a rapamycin to an animal subject, including a human animal subject, comprising:a. preparing or otherwise obtaining a microparticle pharmaceutical preparation, comprising:
i. a solid excipient matrix comprising a polymer composition that remains intact when exposed to acidic conditions of the alimentary canal of an animal of the type of said subject animal and that disintegrates when exposed to basic conditions of targeted portions of said alimentary canal, said polymer composition comprising a copolymer of methacrylic acid; and
ii. nanoparticles dispersed within said solid excipient matrix, said nanoparticles comprising a micelle-inducing compound comprising sodium cholate and a pharmaceutically active core;
iii. said pharmaceutically active core comprising a rapamycin;
iv. said micelle-inducing compound naturally inducing formation of micelles within a solution of said micelle-inducing compound, said micelles having properties that promote stability of said rapamycin when said nanoparticles are dispersed within said matrix; and
b. orally administering said preparation to said animal subject multiple times per week over a multi-week duration, in efficacious amounts, wherein said animal subject is in need of or treatment, or delayed progression, of one or more oncologic, neurologic or autoimmune maladies.
US Pat. No. 10,390,548

METHOD FOR EXTRACTING PEA PROTEINS

Cosucra Groupe Warcoing S...

1. A method for extracting pea proteins, comprising the steps of:(a) subjecting an aqueous composition comprising peas to fermentation;
(b) milling said peas;
(c) fractionating said milled peas so as to obtain at least one protein comprising fraction; and;
(d) isolating pea proteins from said at least one protein comprising fraction.
US Pat. No. 10,391,060

PARTICULATE DELIVERY SYSTEMS

RUBICON RESEARCH PRIVATE ...

1. A particulate delivery system comprising plurality of particles comprising fenugreek gum and at least one pharmaceutically acceptable excipient, wherein the fenugreek gum comprises not less than about 15% by weight of galactomannan.
US Pat. No. 10,392,600

METHOD OF GENERATING HUMAN PANCREATIC CELLS

ICAHN School of Medicine ...

1. A method for generating human pancreatic cells comprising the steps of:i) culturing human embryoid bodies in the presence of a concentration of 100 ng/ml of activin such that a cell population enriched for endoderm is obtained; and ii) differentiating the cell population enriched for endoderm obtained in step i) under conditions such that human pancreatic cells are generated.
US Pat. No. 10,391,062

DRY TRANSGLUTAMINASE COMPOSITION

Novo Nordisk Healthcare A...

1. A dry Factor XIII composition comprising (a) a Factor XIII compound, (b) monovalent salt, and (c) at least one further component selected from the group consisting of a sugar and an amino acid; wherein the Factor XIII compound is selected from the group consisting of wild-type Factor XIII and a dimer of A subunits of Factor XIII; wherein the monovalent salt is in an amount corresponding to a concentration of 20-60 mM when the composition is reconstituted with 3 ml of water; and wherein the composition achieves a level of non-proteolytically activated Factor XIII that constitutes no more than 1% of the total Factor XIII content when measured after reconstitution after being stored at 25° C. for 2 months.
US Pat. No. 10,392,602

METHOD OF DERIVING LACRIMAL GLAND EPITHELIAL CELLS FROM ES CELLS AND OTHER STEM CELLS

KEIO UNIVERSITY, Tokyo (...

1. A method of producing a human lacrimal gland epithelial cell expressing lactoferrin, cytokeratin 15, aquaporin 5, fibroblast growth factor 10 and Homeobox protein BarX-like 2 as cell markers in vitro, comprising the following step A:Step A: a step including increasing expression of paired box 6 gene in a human embryonic stem cell or a human induced pluripotent stem cell, or transfecting paired box 6 protein thereinto, and increasing expression of forkhead box C1 gene or forkhead box P1 gene in the human embryonic stem cell or the human induced pluripotent stem cell, or transfecting forkhead box C1 protein or forkhead box P1 protein thereinto.
US Pat. No. 10,391,064

MICROBIOTA RESTORATION THERAPY (MRT) COMPOSITIONS AND METHODS OF MANUFACTURE

REBIOTIX, INC., Rosevill...

1. A microbiota restoration therapy composition for oral delivery, comprising:a processed human fecal preparation encapsulated in one or more capsules;
wherein the processed human fecal preparation is manufactured by:
collecting a fresh human fecal sample;
adding a diluent to the fresh human fecal sample to form a diluted sample;
wherein the diluent includes 30-90 g/L polyethylene glycol in saline;
mixing the diluted sample with a mixing apparatus;
filtering the mixture;
transferring a filtrate from the filtering step to a centrifuge tube;
centrifuging the filtrate to arrive at the purified intermediate;
lyophilizing the purified intermediate to form a plurality of lyophilized pellets; and
encapsulating the plurality of lyophilized pellets in the one or more capsules.
US Pat. No. 10,392,603

METHOD OF VIRAL PURIFICATION

The Chemo-Sero-Therapeuti...

1. A method of producing a virus in cell culture comprising at least the steps of:a) providing a population of cells in a cell culture medium,
b) infecting the population of cells by:
i. inoculating the population of cells with the virus, and
ii. incubating the inoculated population of cells so as to allow the virus to replicate and propagate,
c) collecting the produced virus, thereby providing a viral harvest, and
d) purifying the virus,
wherein a volumetric power input of at least 15 W/m3, at least 30 W/m3, at least 60 W/m3, at least 100 W/m3, or at least 120 W/m3 is applied to the cell culture at least during step b) and
wherein during step b) i, the volumetric power input is reduced to 2 to 10 W/m3.
US Pat. No. 10,390,553

FOOD CONTAINING HISTIDINE AND USE THEREOF

AJINOMOTO CO., INC., Tok...

1. A method of improving mental energy, which comprises administering not less than 0.3 g of histidine as an ingestion amount per meal to a human subject in need thereof, wherein said subject exhibits a Pittsburgh Sleep Quality Index (PSQI) of not less than 6 and/or a factor T score of not less than 60 points in Profile of Mood Sates (POMS),wherein said histidine is administered in a liquid composition which comprises histidine in an amount not less than 3 w/v % wherein said subject is a human of 45 years old to less than 65 years old.
US Pat. No. 10,391,065

METHOD FOR MAKING A TRANSDERMAL FENTANYL PATCH WITH EVEN DRUG CRYSTAL DISTRIBUTION

1. A method for making a medical device for transdermal administration of a drug, the method comprising the steps of:a. micronizing a drug to a particle size of less than about 40 microns;
b. dispersing the drug in a first solvent of heptane to form a uniform suspension of particles of the drug;
c. forming an adhesive solution of an adhesive and a second solvent of heptane; and
d. adding the uniform suspension quantitatively to the adhesive solution to add the drug the drug from the uniform suspension to the adhesive solution,
wherein all the particles of the drug suspended in the uniform suspension are crystalline particles having a particle size which is not larger than an initial particle size of the drug.
US Pat. No. 10,392,604

ATTENUATED INFLUENZA VECTORS FOR THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASES AND FOR THE TREATMENT OF ONCOLOGICAL DISEASES

PHARMENTERPRISES BIOTECH ...

1. An attenuated influenza A virus inducing a cross-protective response against influenza A and B viruses, comprising a chimeric NS fragment including a truncated reading frame of an NS1 protein and a Nep gene heterologous sequence, wherein said truncated reading frame of the NS1 protein is derived from H1N1 influenza virus subtype, and the Nep gene heterologous sequence is derived from H2N2 influenza virus subtype and wherein said truncated reading frame encodes the NS1 protein consisting of 124 amino acid residues corresponding to SEQ ID NO: 4.
US Pat. No. 10,392,605

P97-IDS FUSION PROTEINS

Bioasis Technologies Inc....

1. A p97 (melanotransferrin) fusion protein, comprising an iduronate-2-sulfatase (IDS) polypeptide fused to the N-terminus of a p97 polypeptide fragment and an optional heterologous peptide linker (L) in between, wherein the p97 polypeptide fragment consists of the amino acid sequence having at least 80% sequence identity to DSSHAFTLDELR (SEQ ID NO: 14) and having transport activity.
US Pat. No. 10,392,606

MATERIALS AND METHODS FOR USING AN ACYL-ACYL CARRIER PROTEIN THIOESTERASE AND MUTANTS AND CHIMERAS THEREOF IN FATTY ACID SYNTHESIS

Iowa State University Res...

1. An isolated or purified nucleic acid molecule comprising a nucleotide sequence encoding a mutant plant acyl-acyl carrier protein thioesterase (acyl-ACP TE), the amino acid sequence of which is at least 85% identical to the amino acid sequence of SEQ ID NO:3 and which comprises a substrate specificity-altering mutation in the region corresponding to amino acids 118-167 of SEQ ID NO:3, wherein said substrate specificity-altering mutation includes at least one amino acid corresponding to an amino acid selected from the group consisting of amino acid 133, amino acid 139, amino acid 142, and amino acid 143 of SEQ ID NO:3, alone or in further combination with a substrate-specificity altering mutation in the region corresponding to amino acids 73-85 of SEQ ID NO:3,wherein the isolated or purified nucleic acid molecule can be in a vector.
US Pat. No. 10,393,374

PROCESS FOR THE INCINERATION OF ACTIVATED COAL-SUPPORTED PGM CATALYSTS

HERAEUS PRECIOUS METALS N...

1. A process for the incineration of activated coal-supported PGM catalysts, the process comprising a joint incineration of a multilayer arrangement,wherein the multilayer arrangement comprises (i) a top layer of particulate activated coal-supported PGM catalyst, (ii) a layer of coarse charcoal located beneath said top layer and, optionally, (iii) a layer of particulate coke located beneath the charcoal layer, and
wherein an upward flow of oxidizing gas is homogeneously passed through said multilayer arrangement during the incineration.
US Pat. No. 10,392,607

CAS9 VARIANTS AND METHODS OF USE THEREOF

the regents of the univer...

1. A variant Cas9 protein with reduced RuvC cleavage activity relative to a corresponding wild type Cas9 protein, the variant Cas9 protein comprising:a RuvC domain,
an HNH domain, and
a disrupted RuvC/HNH linker region that reduces the RuvC cleavage activity of the variant Cas9 protein relative to the RuvC cleavage activity of the corresponding wild type Cas9 protein.
US Pat. No. 10,393,631

SIMPLIFIED EXTRACTION METHODS FOR THE RAPID DETERMINATION OF SPECIES CONTENT OF ADIPOSE TISSUE BASED ON THE DETECTION OF TNI IN IMMUNOASSAYS

Florida State University ...

1. A method comprising:extracting proteins from an animal muscle-free adipose tissue sample with a phosphate buffered saline to form an aqueous protein extract comprising the phosphate buffered saline and soluble proteins extracted from the animal muscle-free adipose tissue sample by the phosphate buffered saline without homogenizing the muscle-free adipose tissue sample, and
contacting the aqueous protein extract with a species-specific anti-troponin I monoclonal antibody to test whether the species-specific anti-troponin I monoclonal antibody binds to a protein in the aqueous protein extract,
wherein the species-specific anti-troponin I monoclonal antibody is directly or indirectly conjugated to a label that shows the binding of the species-specific anti-troponin I monoclonal antibody with a species-specific troponin I, and
wherein binding of the species-specific anti-troponin I monoclonal antibody to a protein in the aqueous protein extract indicates a presence of the species-specific troponin I in the animal muscle-free adipose tissue sample.
US Pat. No. 10,392,608

DIMERIC BACTERIOPHAGE LYSINS

The Rockefeller Universit...

1. An isolated dimeric phage lysin comprising two phage lysin monomers specific for bacteria and capable of killing at least one or more Streptococcus bacteria covalently linked to each other, wherein said dimer has killing activity against one or more Streptococcus bacteria that is greater than the killing activity of any one of the phage lysin monomers, and wherein the lysin monomers are covalently associated or cross-linked via reactive groups or via amino acids in each monomer sequence.
US Pat. No. 10,393,632

ENCAPSULATED REAGENTS AND METHODS OF USE

1. A solution in combination with an analytic substrate having a biological specimen treated with a horseradish peroxidase staining protocol disposed thereon, the solution comprising:a carrier solution disposed on the analytic substrate, the carrier solution comprising a 3,3?-diaminobenzidine chromogen activating buffer; and
a plurality of capsules dispersed in the carrier solution, the capsules encapsulating at least one reagent comprising a 3,3?-diaminobenzidine chromogen,
wherein the solution is positioned on the analytic substrate such that disruption of the capsules causes the release of the reagent into the carrier solution so that the reagent is activated by the 3,3?-diaminobenzidine chromogen activating buffer and becomes available to act on or react with a horseradish peroxidase of the horseradish peroxidase staining protocol attached to or associated with the biological specimen.
US Pat. No. 10,393,633

SAMPLE FIXATION AND STABILISATION

RNASSIST LTD., Cambridge...

1. A method of inhibiting the degradation of a sample, comprising (a) mixing said sample with or immersing said sample in a eutectic solvent comprising a first component and a second component, wherein said first component is trimethylglycine and said second component is trifluoroacetamide; wherein said first component and said second component are in a molar ratio of between about 1:1.5 and about 1:2.5; and wherein said first component and said second component together comprise at least about 50% by weight of the combined eutectic solvent and sample; (b) incubating said sample and eutectic solvent of (a) for at least 5 minutes; and (c) processing said sample, wherein said processing comprises: microscopic examination of said sample; staining said sample; performing flow cytometry on said sample; embedding said sample; sectioning said sample; performing in situ hybridisation on said sample; performing an immunohistochemical method on said sample; detecting a protein in said sample; detecting a phosphoprotein in said sample; detecting DNA or RNA in said sample; or performing an immunocytochemical method on said sample.
US Pat. No. 10,394,145

TONER FOR ELECTROPHOTOGRAPHY

Kao Corporation, Chuo-ku...

1. A method for producing a toner for electrophotography, comprising:(1) mixing a polyester and a polylactic acid at a temperature of 140° C. or higher and 200° C. or lower and subjecting the mixture to a transesterification reaction to provide a resin composition; and
(2) mixing the resin composition obtained from said (1) mixing with a polyester which is identical to or different from the polyester of said (1) mixing, in a production of a toner for electrophotography.
US Pat. No. 10,391,071

COMPOSITIONS COMPRISING VALERIAN EXTRACTS

CUTECH SRL, Padua (IT)

1. A method for treating scalp disorders caused by excessive sebogenesis, comprising topically administering on the scalp a composition comprising a valerian extract or an ester obtained from the combination of acid contained in the valerian extract with an aliphatic alcohol, in an amount effective for reducing sebum content, thereby treating the scalp disorders caused by the excessive sebogenesis.
US Pat. No. 10,392,610

PREGNANCY-ASSOCIATED PLASMA PROTEIN-A2 (PAPP-A2) POLYPEPTIDES

Como Biotech ApS, Aarhus...

1. An isolated polypeptide which comprises an amino acid sequence that differs from residues 234-1791 of SEQ ID NO:2 solely by(a) addition of 1-10 residues to the amino terminal; and/or
(b) addition of 1-10 residues to the carboxy terminal; and/or
(c) one or more conservative substitutions;wherein said polypeptide has a proteolytic activity against Insulin Like Growth Factor Binding Protein 5 (IGFBP-5), and wherein said amino acid sequence is at least 95%, but not 100%, identical to residues 234-1791 of SEQ ID NO:2.
US Pat. No. 10,394,146

BINDER RESIN FOR TONERS, TONER, AND METHOD FOR PRODUCING SAME

Mitsubishi Chemical Corpo...

1. A binder resin, comprising:a polyester resin (A) comprising a constitutional unit derived from isosorbide and has a softening temperature of higher than 120° C.; and
a polyester resin (B) different from the polyester resin (A),
wherein
the binder resin has a pulverizability index of 25 or more,
a weight average molecular weight (Mw) of the polyester resin (B) is from 500 to 1,000,000, and
a glass transition temperature of the polyester resin (B) is from 35° C. to 82° C.
US Pat. No. 10,391,072

HIGH CONTENT SODIUM IBUPROFEN GRANULES, THEIR PREPARATION AND THEIR USE IN PREPARING NON-EFFERVESCENT SOLID DOSAGE FORMS

SI GROUP, INC., Schenect...

1. A process of preparing highly dispersible free-flowing granules of sodium ibuprofen dihydrate, comprising:bringing together in a high shear granulator components comprised of (i) at least 80 parts by weight on a dry basis of sodium ibuprofen dihydrate, (ii) 1 to 4 parts by weight on a dry basis of sodium carbonate, (iii) 1 to 15 parts by weight on a dry basis of non-crosslinked polyvinylpyrrolidone, and (iv) 8 to 12 parts by weight of water based on the total weight of (i), (ii), (iii), and (iv) to form a wet mixture;
granulating said wet mixture in said high shear granulator to form wet granules;
drying wet granules to form dried granules having a moisture content in the range of about 11 to 15 wt % as determinable by measurement of weight loss at 110° C.; and
removing by sieving dried granules having a particle size greater than 16 mesh,wherein the prepared highly dispersible free-flowing granules do not form punch coating when being subjected to a tablet-forming process.
US Pat. No. 10,392,611

POLYMER CONJUGATES HAVING REDUCED ANTIGENICITY AND METHODS OF USING THE SAME

Duke University, Durham,...

1. A molecule-polymer conjugate having reduced or eliminated antigenicity compared to a control, the molecule-polymer conjugate comprising:a branched polymer comprising poly[oligo(ethylene glycol) methyl ether methacrylate] (POEGMA); and
a molecule conjugated to the backbone of the branched polymer, wherein the molecule comprises a uricase,
wherein the POEGMA comprises:
a backbone comprising poly(methyl methacrylate); and
a plurality of side chains covalently attached to the backbone, where each side chain comprises 2 to 9 monomers of ethylene glycol (EG) repeated in tandem;
and wherein the molecule-POEGMA conjugate is not reactive with pre-existing anti-PEG antibodies in a subject.
US Pat. No. 10,391,074

TOPICAL PREPARATION FOR PAIN RELIEF

Sambria Pharmaceuticals, ...

1. A method of reducing a sensation of pain in a subject, comprising:applying topically directly to skin of the subject over an area of pain a therapeutic amount of a composition comprising
(a) lidocaine in an amount of about 1% to about 20%; and
(b) a penetration enhancer comprising a penetration-enhancing amount of a methylsulfonylmethane (MSM) component, and an ethoxydiglycol component, wherein the amount of the MSM component is about 1% to about 10%, and the amount of the ethoxydiglycol component is about 0.10% to about 5%,wherein the composition is effective(i) to deeply penetrate the skin of the subject,
(ii) to remain in the skin and block nerve signals affecting sensation of pain, and
(iii) to provide pain relief.
US Pat. No. 10,391,330

NON-INVASIVE SYSTEMS AND METHODS FOR IN-SITU PHOTOBIOMODULATION

IMMUNOLIGHT, LLC, Detrio...

1. A method for neuronal stimulation in a subject, comprising:administering at least one biocompatible phosphorescent molecule to a region of a subject in need of neuronal stimulation, wherein the at least one biocompatible phosphorescent molecule is selected to have an emitted energy to be of a wavelength sufficient to cause the neuronal stimulation and increases a wavelength of an X-ray initiation energy; and
applying the X-ray initiation energy from at least one source, wherein the X-ray initiation energy is converted by the at least one biocompatible phosphorescent molecule into the emitted energy that directly causes neuronal stimulation in the region of the subject.
US Pat. No. 10,392,613

PURIFICATION OF NUCLEIC ACIDS USING COPPER-TITANIUM OXIDES

ABBOTT MOLECULAR INC., D...

1. A method of capturing RNA and/or DNA from a biological sample, comprising:a) contacting said sample with a particle or solid surface comprising or coated with a metal oxide such that DNA and/or RNA in said sample binds said particle wherein said metal oxide is CuTi;
b) washing said particle or solid surface to remove contaminants; and
c) eluting RNA and/or DNA from said particle or solid surface.
US Pat. No. 10,394,149

BINDER RESIN COMPOSITION FOR ELECTROSTATIC IMAGE DEVELOPING TONERS

Kao Corporation, Tokyo (...

1. A resin binder composition for toners for development of electrostatic images comprising a polyester-based resin and a polypropylene-based wax (W-1),wherein:
the polyester-based resin is in the form of a composite resin (HB) comprising a polyester-based resin segment (A) and a vinyl-based resin segment (B) comprising a constitutional unit derived from a vinyl-based monomer comprising an alkyl group having not less than 10 and not more than 22 carbon atoms in an amount of not less than 1% by mass and not more than 70% by mass;
a mass ratio of the polyester-based resin segment (A) to the vinyl-based resin segment (B) [(A)/(B)] in the composite resin (HB) is not less than 40/60 and not more than 95/5; and
the resin binder composition has an endothermic amount ratio ?HCW/W of not less than 0.10 and not more than 0.80, the endothermic amount ratio ?HCW/W being represented by the following formula (1):
Endothermic Amount Ratio ?HCW/W=?HCW/?HW  (1)
wherein ?HCW is an endothermic amount of a melting endothermic peak per 1 g of the polypropylene-based wax (W-1) as measured with respect to the resin binder composition;and ?HW is an endothermic amount of a melting endothermic peak per 1 g of the polypropylene-based wax (W-1) as measured with respect to the polypropylene-based wax (W-1) singly,?HCW and ?HW each representing an endothermic amount as measured at a temperature rise rate of 10° C./min using a differential scanning calorimeter.
US Pat. No. 10,392,614

METHODS OF SINGLE-CELL BARCODING AND SEQUENCING

AbVitro LLC, Seattle, WA...

1. A method comprising:producing a plurality of cDNAs from a plurality of polynucleotides, wherein at least one polynucleotide encodes a heavy and/or light chain, from a plurality of immune cells from a biological sample, the producing comprising:
(i) reverse transcribing a sequence complementary to a sequence downstream of a variable region of the at least one polynucleotide encoding a heavy and/or light chain, using:
(A) a first plurality of primers, and
(B) a reverse transcriptase comprising a non-template terminal transferase activity, wherein 3 or more identical non-template nucleotides are added to a 3? end of the cDNAs, and
(ii) template switching, using a plurality of template switch polynucleotides, each comprising:
(A) a unique barcode,
(B) a first primer binding site 5? to the unique barcode, and
(C) a 3? end region complementary to the 3 or more identical non-template nucleotides,
thereby forming a plurality of uniquely barcoded cDNAs; wherein the reverse transcribing and the template switching are performed in an emulsion;wherein the method optionally further comprises:(a) amplifying the plurality of uniquely barcoded cDNAs, thereby forming a library of uniquely barcoded sequences comprising a variable region of the heavy (VH) or light (VL) chain polynucleotides;and wherein the method further optionally comprises:(b) sequencing one or more of the sequences of the library.
US Pat. No. 10,392,615

METHODS FOR RNA PROMOTER IDENTIFICATION

THE REGENTS OF THE UNIVER...

1. A RNA construct comprising the following operably linked polynucleotide elements in the 5? to 3? direction:i) a hammerhead ribozyme catalytic core;
ii) a first hairpin ribozyme cleavage site in the antisense orientation;
iii) a non-functional or stuffer polynucleotide;
iv) a second hairpin ribozyme cleavage site in the antisense orientation;
v) a hairpin ribozyme catalytic core in the antisense orientation;
vi) reverse and forward primer annealing sites in the antisense orientation; and
vii) an inserted polynucleotide suspected of comprising a RNA promoter.
US Pat. No. 10,394,151

ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, ELECTROSTATIC CHARGE IMAGE DEVELOPER, AND TONER CARTRIDGE

FUJI XEROX CO., LTD., To...

1. An electrostatic charge image developing toner comprising:a toner particle;
a strontium titanate particle that is externally added to the toner particle and that is doped with a metal element having an electronegativity of 1.3 or less; and
a silica particle that is externally added to the toner particle,
wherein, the silica particle is a particle having a volume average particle diameter of 50 nm or more and 250 nm or less, a detected peak intensity of the metal element which is obtained by an X-ray fluorescence element analysis method is Me-R, a detected peak intensity of strontium which is obtained by an X-ray fluorescence element analysis method is Sr—R, a detected peak intensity of silicon which is obtained by an X-ray fluorescence element analysis method is Si—R, and an element proportion of strontium obtained by an X-ray photoelectron spectroscopy method is Sr—P,
in the X-ray fluorescence element analysis method, an amount of elements which are present inside and on the surface of the toner obtained by externally adding an external additive to the toner particles is determined, and Conditions (1) to (3) are satisfied,
0.08 kcps?Me-R?10 kcps,  (1)
0.1%?Sr—P?3.0%, and  (2)
0.15?Sr—R/Si—R?12.  (3)
US Pat. No. 10,394,152

TONER, TONER CONTAINER, DEVELOPING UNIT, AND IMAGE FORMING APPARATUS

Oki Data Corporation, To...

1. A toner, comprising:an external additive particle that is a complex oxide containing a titanium dioxide (TiO2) and a silicon dioxide (SiO2), wherein
a detection amount of titanium (Ti) detected through an elementary analysis based on energy-dispersive X-ray spectrometry is equal to or higher than 0.590 percent by weight and equal to or lower than 0.967 percent by weight.
US Pat. No. 10,391,078

METHODS FOR THE TREATMENT OF MAST CELL RELATED DISORDERS WITH MAST CELL STABILIZERS

Respivant Sciences GmbH, ...

1. A method of treating a subject having a mast cell related disorder, comprising administering to the subject an effective amount of a composition comprising cromolyn, or a salt thereof, using an inhalation device that produces in the subject an AUC(0-?) of cromolyn of from about 5.3 ng*h/mL to about 8.5 ng*h/mL per milligram of cromolyn, or a salt thereof, administered to the subject, and wherein the mast cell related disorder is selected from primary biliary cirrhosis, secondary sclerosing cholangitis due to mast cell cholangiopathy, itching caused by or associated with primary biliary cirrhosis, bronchiolitis obliterans syndrome after lung transplantation, bronchopulmonary dysplasia in infants, cardiac fibrosis, atrial fibrosis, primary sclerosing cholangitis (PSC), chronic pelvic pain syndrome (prostatitis), viral pneumonia caused by respiratory syncytial virus, and interstitial lung disease.
US Pat. No. 10,392,617

MIR-122* AS AN ACTIVE MICRO-RNA, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF

HADASIT MEDICAL RESEARCH ...

1. A method of treating cancer in a subject in need thereof, the method comprising administering a miR-122* polynucleotide molecule, comprising at least one modified nucleotide, thereby treating cancer in the subject.
US Pat. No. 10,391,079

METHODS OF DIAGNOSING AND TREATING ALZHEIMER'S DISEASE WITH S-EQUOL

AUSIO PHARMACEUTICALS, LL...

1. A method for improving a cognitive measurement in a patient at risk of or diagnosed with Alzheimer's disease comprising administering a pharmaceutically effective amount of a formulation comprising S-equol to said patient, wherein there is an absence of genistein, daidzein, and/or IBS003569 in said formulation, and wherein said administration results in an increased ratio of platelet mitochondria cytochrome oxidase (COX) to citrate synthase (CS) in a blood sample obtained from said patient.
US Pat. No. 10,392,618

MICRO-RNA FAMILY THAT MODULATES EXTRACELLULAR MATRIX GENES AND USES THEREOF

THE BOARD OF REGENTS, THE...

1. A method of decreasing expression of one or more extracellular matrix genes in a subject in need thereof comprising administering to the subject a polynucleotide comprising a pri-miR-29a, a pri-miR-29b, a pre-miR-29a, a pre-miR-29b, a mature sequence of miR-29a, or a mature sequence of miR-29b, wherein the expression of one or more extracellular matrix genes in the subject is reduced following administration of the polynucleotide, and wherein the subject does not suffer from cardiac fibrosis.
US Pat. No. 10,394,154

ELECTROPHOTOGRAPHIC COMPOSITION

HP Indigo B.V., Amstelve...

1. An electrophotographic composition comprising toner particles dispersed in a liquid carrier, wherein the toner particles comprise a polymer resin and porous silica particles infused with a fragrance.
US Pat. No. 10,391,080

KETOROLAC FOR THE TREATMENT OF CANCER

Cipla Limited, Mumbai (I...

1. A method for the treatment of renal cell carcinoma in a patient, the method comprising administering to said patient ketorolac, or a pharmaceutically acceptable salt or ester thereof, in an amount effective to treat renal cell carcinoma.
US Pat. No. 10,392,619

METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING OLIGONUCLEOTIDE BASED DRUGS ADMINISTERED IN VIVO OR IN VITRO


where:
a) I is an individual nucleoside;
b) dash (-) is an internucleoside linkage;
c) N=3 to 7 of additional nucleosides;
d) nucleosides adjacent to the argonaute 2 cleavage site on the target RNA are shown in bold and italics while the adjacent two nucleosides are shown in italics only;
e) nucleotides and linkages which modulate activity of argonaute 2 are in the underlined central region of the strand;
wherein the underlined nucleosides have one of the following configurations:
(ia) alternating 2?-fluoro and 2?-O-methyl sugar modifications; or
(ib) 1, 2, or 3, 2?-fluoro sugar modifications alternating with 1, 2 or 3, 2? O-methyl group sugar modifications, with no more than 3 contiguous nucleosides having the same type of 2? sugar modification;
(ii) 2?-fluoro with ribose with no more than 3 contiguous nucleosides having the 2?-fluoro moiety; or
(iii) 2?-O-methyl with ribose with no more than 3 contiguous nucleosides having the 2?-O-methyl moiety;
(iv) nucleosides flanking the underlined region comprising one or modifications selected from the group consisting of 2?-fluoro, 2?-O-methyl, or is native ribose;
v) linkages are a mixture of phosphorothioate and phosphodiester wherein no more than three of the five linkages indicated by ˜ in the strand are phosphorothioate and no more than two of said phosphorothioate linkages are contiguous;
vi) the majority of the linkages flanking the underlined sequence in the strand, or all are phosphorothioate; and
vii) wherein the hydroxyl group in the nucleoside at the 5? end is optionally replaced with a 5?phosphate, said strand being effective to induce degradation of said target ribonucleotide acid within said cell, wherein said target RNA is PTEN and said ss-RNA has the sequence of SEQ ID NO: 221.
US Pat. No. 10,392,363

METHODS FOR TREATING PROTOZOAN INFECTIONS

Neoculi Pty Ltd., Victor...


US Pat. No. 10,392,620

CYTOCHROME B (CYTB) NUCLEIC ACID MOLECULES THAT CONTROL PATHOGENS

Dow AgroSciences LLC, In...

1. A double-stranded nucleic acid comprising a ribonucleic acid (RNA) molecule that is specifically hybridizable with a polynucleotide from a phytopathogen from the genus Zymoseptoria selected from the group consisting of:SEQ ID NO:4; a complement of SEQ ID NO:4; a fragment of at least 21 contiguous nucleotides of SEQ ID NO:4;
SEQ ID NO:5; a complement of SEQ ID NO:5; a fragment of at least 21 contiguous nucleotides of SEQ ID NO:5;
SEQ ID NO:6; a complement of SEQ ID NO:6; a fragment of at least 21 contiguous nucleotides of SEQ ID NO:6; and,
SEQ ID NO:7; a complement of SEQ ID NO:7; a fragment of at least 21 contiguous nucleotides of SEQ ID NO:7, wherein the double-stranded nucleic acid inhibits or down regulates the polynucleotide.
US Pat. No. 10,392,621

MULTIAPTAMER TARGET DETECTION

SomaLogic, Inc., Boulder...

1. A method for detecting a target in a sample, the method comprising:a) contacting the sample with a first aptamer to form a mixture, wherein the first aptamer is capable of binding to the target to form a first complex;
b) incubating the mixture under conditions that allow for the first complex to form;
c) contacting the mixture with a second aptamer, wherein the second aptamer is capable of binding the first complex to form a second complex;
d) incubating the mixture under conditions that allow for the second complex to form;
e) detecting for the presence or absence of the first aptamer, the second aptamer, the target, the first complex or the second complex in the mixture, wherein the presence of the first aptamer, the second aptamer, the target, the first complex or the second complex indicates that the target is present in the sample; and
wherein, the first aptamer comprises a first C-5 pyrimidine modification scheme, the second aptamer comprises a second C-5 pyrimidine modification scheme, and wherein the first C-5 pyrimidine modification scheme and the second C-5 pyrimidine modification scheme are different,
further wherein the first C-5 pyrimidine modification scheme comprises a 5-(N-benzylcarboxyamide)-2?-deoxyuridine (BndU).
US Pat. No. 10,392,623

L-ARABINOSE ASSIMILATION PATHWAY AND USES THEREOF

DEINOVE, Grabels (FR)

1. A recombinant host cell comprising a heterologous nucleic acid construct, expression cassette or vector comprising:a nucleic acid sequence encoding a polypeptide comprising an amino acid sequence having at least 95% identity to SEQ ID NO: 5 and exhibiting L-ribulose-5-phosphate 4 epimerase activity, or a functional fragment thereof, and/or
a nucleic acid sequence encoding a polypeptide comprising an amino acid sequence having at least 95% identity to SEQ ID NO: 1 and exhibiting L-arabinose isomerase activity, or a functional fragment thereof, and/or
a nucleic acid sequence encoding a polypeptide comprising an amino acid sequence having at least 95% identity to SEQ ID NO: 3 and exhibiting L-ribulokinase activity, or a functional fragment thereof,
wherein the functional fragment is at least 100 contiguous amino acids of said polypeptide, and retains the enzymatic activity of the entire polypeptide.
US Pat. No. 10,391,085

METHODS OF TREATING GLIOBLASTOMA MULTIFORME USING IBUDILAST

MediciNova, Inc., La Jol...

1. A method of treating a patient diagnosed with glioblastoma or suffering from recurrent glioblastoma comprising administering to the patient a therapeutically effective amount of ibudilast or a pharmaceutically acceptable salt thereof, as part of a combination therapy comprising at least one additional therapy, wherein the at least one additional therapy comprises laquinimod.
US Pat. No. 10,392,624

GENE ENGINEERING YEAST HAVING SACCHARIFICATION FUNCTION, METHOD OF PREPARING SAME, AND APPLICATION OF SAME

ANGEL YEAST CO., LTD, Yi...

1. A yeast host cell, comprising an exogenous nucleic acid having a nucleotide sequence encoding a glucoamylase,wherein the nucleotide sequence is selected from the group consisting of:
(a) a nucleotide sequence encoding the amino acid sequence of SEQ ID NO: 16; and
(b) a nucleotide sequence comprising SEQ ID NO:15 and encodes the glucoamylase, and
wherein the yeast host cell is the Saccharomyces cerevisiae strain deposited with the China Center for Type Culture Collection as Deposit Accession No. CCTCC M 2014657.
US Pat. No. 10,391,086

USE OF EP4 RECEPTOR ANTAGONISTS IN THE TREATMENT OF CARTILAGE DISEASE

AskAt Inc., Aichi (JP)

1. A method for inhibiting cartilage destruction, which comprises orally administering to an animal or a human in need thereof a therapeutically effective amount of 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl}phenyl)ethyl]-1-[(4-methylbenzene)sulfonyl]urea or a pharmaceutically acceptable salt thereof,wherein the therapeutically effective amount of the 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl}phenyl)ethyl]-1-[(4-methylbenzene)sulfonyl]urea or pharmaceutically acceptable salt thereof which is orally administered to the human is about 1 mg/day to about 1000 mg/day, and
wherein the therapeutically effective amount of the 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl}phenyl)ethyl]-1-[(4-methylbenzene)sulfonyl]urea or pharmaceutically acceptable salt thereof which is orally administered to the animal is about 0.1 mg/kg/day to about 10 mg/kg/day.
US Pat. No. 10,392,625

HOST CELLS AND METHODS OF USE

GlaxoSmithKline LLC, Wil...

1. A genetically modified Pichia pastoris strain of wild type X-33 or SMD1163, wherein a nucleic acid sequence encoding a YMP1 secreted serine protease having the nucleic acid sequence of SEQ ID NO: 3 is deleted, mutated or disrupted within wild type X-33 or SMD1163 to produce a reduced amount of activity or no activity of the YMP1 secreted serine protease compared with the wild type strain, and wherein the modified Pichia pastoris strain has reduced proteolysis and/or glycosylation.
US Pat. No. 10,391,087

COMBINATION OF OXYMETAZOLINE AND IPRATROPIUM IN TOPICAL NASAL APPLICATION FOR THE TREATMENT OF A COUGH

1. A pharmaceutical composition for treatment for a cough caused by a posterior nasal secretion, comprising ipratropium bromide or a pharmaceutically acceptable salt and oxymetazoline hydrochloride or a pharmaceutically acceptable salt, for the preparation of an intranasal drug;wherein the treatment is formulated in the form of an aqueous solution comprising Ipratropium bromide in dilutions of 105.0, 52.5 and 21.0 mg/100 mL, and oxymetazoline hydrochloride in dilutions of 50.0, 25.0 and 10.0 mg/100 mL, for adult, children, and pediatric respectively.
US Pat. No. 10,392,626

PLANT REGULATORY ELEMENTS AND USES THEREOF

Monsanto Technology LLC, ...

1. A recombinant polynucleotide comprising:a) a genetic regulatory element operably linked to a 5? end of a leader regulatory element comprising SEQ ID NO:1 or SEQ ID NO:4 operably linked to a 5? end of a heterologous transcribable polynucleotide, wherein the recombinant polynucleotide lacks nucleotides 1 to 274 of SEQ ID NO:6; or
b) a genetic regulatory element operably linked to a 5? end of a leader regulatory element comprising SEQ ID NO:1 or SEQ ID NO:4 operably linked to a 5? end of a transcribable polynucleotide, wherein the recombinant polynucleotide lacks nucleotides 1 to 274 of SEQ ID NO:6, wherein the transcribable polynucleotide comprises a sequence encoding the polypeptide of SEQ ID NO:3.
US Pat. No. 10,392,627

METHODS AND COMPOSITIONS FOR EXPRESSION CASSETTES COMPRISING A MAIZE GENE-DERIVED INTRON FOR ENHANCED EXPRESSION

Syngenta Participations A...

1. An expression cassette comprising a promoter operably linked to a nucleic acid molecule of interest, which is operably linked to a terminator, further comprising a heterologous intron that enhances expression of the nucleic acid molecule of interest,wherein the heterologous intron is heterologous to at least one of the nucleic acid molecule of interest, the promoter, and the terminator, and
wherein the heterologous intron is selected from the group consisting of SEQ ID NO: 1 and SEQ ID NO: 2.
US Pat. No. 10,392,628

BRASSICA NAPUS ACC OX PROMOTER IDENTIFIED BY MICROARRAY ANALYSIS

Dow AgroSciences LLC, In...

1. A gene expression cassette comprising a promoter operably linked to a heterologous coding sequence, wherein the promoter comprises a polynucleotide that shares a sequence identity of at least 98% to SEQ ID NO:1.
US Pat. No. 10,391,090

METHODS FOR SOLID TUMOR TREATMENT

Crititech, Inc., Lawrenc...

1. A method for treating a solid tumor, comprising administering to a subject with a solid prostate tumor an amount effective of a composition comprising chemotherapeutic particles to treat the prostate tumor, wherein the composition is directly injected into the prostate tumor, wherein the chemotherapeutic particles comprise at least 95% paclitaxel or a pharmaceutically acceptable salt thereof, and wherein the chemotherapeutic particles have a specific surface area (SSA) of at least 10 m2/g, wherein the chemotherapeutic particles include both agglomerated chemotherapeutic particles and non-agglomerated chemotherapeutic particles.
US Pat. No. 10,392,629

INCREASED CALORIC AND NUTRITIONAL CONTENT OF PLANT BIOMASS

Board of Trustees of Mich...

1. A plant seed or plant comprising a nucleic acid construct comprising a nucleic acid encoding a diacylglycerol acyltransferase polypeptide with at least 95% sequence identity with SEQ ID NO: 3 that is operably linked to a heterologous promoter operable in leaves, wherein the leaves of a plant grown from the plant seed, or the leaves of the plant contain oil droplets than wild type plants.
US Pat. No. 10,391,347

PROCESS FOR BIOCHEMICAL DENATURATION OF AN ASBESTOS-CONTAINING MATERIAL

LEBSC S.R.L, Bologna (IT...

1. A process for treating an asbestos-containing material, which comprises:subjecting a food industry waste material to mixed bacterial and fungal growth and/or fermentation to produce an acidic solution/suspension; and
treating an asbestos-containing material with the acidic solution/suspension at a temperature of 120-170° C. and pressure of 2-10 bar in order to produce an asbestos-containing material that is at least partially inert;
wherein said mixed bacterial and fungal growth and/or fermentation is carried out by using bacteria of the species Acetobacter aceti and yeast of the species Saccharomyces cerevisiae.
US Pat. No. 10,392,630

PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES

BASF AGRO B.V., Arnhem (...

1. A nucleic acid construct comprising, in operable linkage:(1) a nucleic acid molecule encoding a protoporphyrinogen oxidase (PPO) polypeptide selected from the group consisting of:
(a) a nucleic acid molecule encoding the PPO polypeptide comprising the sequence of SEQ ID NO: 2;
(b) a nucleic acid molecule comprising the sequence of SEQ ID NO: 1; and
(c) a nucleic acid molecule encoding a PPO polypeptide having 95% or more identity with the amino acid sequence of SEQ ID NO: 2, wherein transgenic expression of said nucleic acid molecule in a plant cell, a plant, or a plant part confers increased herbicide tolerance or resistance, as compared to a corresponding, non-transformed, wild type plant cell, a wild type plant or a part thereof; and
(2) a heterologous promoter.
US Pat. No. 10,392,631

FUSARIUM CHITIN SYNTHASE GENE CHS3B AND THE USE THEREOF

Huazhong Agricultural Uni...

1. An RNAi construct comprising a fragment of Fusarium chitin synthase gene Chs3b selected from the group consisting of: Chs3b-1 having the nucleotide sequence of SEQ ID NO: 2, Chs3b-2 having the nucleotide sequence of SEQ ID NO: 3, Chs3b-3 having the nucleotide sequence of SEQ ID NO: 4, Chs3b-4 having the nucleotide sequence of SEQ ID NO: 5, and Chs3b-5 having the nucleotide sequence of SEQ ID NO:6.
US Pat. No. 10,391,606

CHEMICAL MECHANICAL POLISHING PADS FOR IMPROVED REMOVAL RATE AND PLANARIZATION

Rohm and Haas Electronic ...

1. A chemical mechanical (CMP) polishing pad having a low damping component for polishing a substrate chosen from at least one of a memory and a semiconductor substrate comprising: a polishing layer adapted for polishing the substrate which is a polyurethane reaction product of a thermosetting reaction mixture comprising a curative of 4,4?-methylenebis(3-chloro-2,6-diethylaniline) (MCDEA) or mixtures of MCDEA and 4,4?-methylene-bis-o-(2-chloroaniline) (MbOCA) in a weight ratio of MCDEA to MbOCA of from 3:7 to 1:0, and a polyisocyanate prepolymer having an unreacted isocyanate (NCO) concentration of from 8.6 to 11 wt. % and formed from one or two aromatic diisocyanates or a mixture of an aromatic diisocyanate and up to 67 wt. % of an alicyclic diisocyanate, based on the total weight of the aromatic and alicyclic diisocyanates, and a polyol of polytetramethylene ether glycol (PTMEG), polypropylene glycol (PPG), or a polyol blend of PTMEG and PPG as reactants, wherein the polyurethane reaction product in the polishing layer has a Shore D hardness according to ASTM D2240-15 (2015) of from 60 to 90, further wherein the polyurethane reaction product in the polishing layer has a shear storage modulus (G?) at 65° C. of from 125 to 500 MPa, and, still further wherein the polishing layer has a damping component (G?/G? measured by shear dynamic mechanical analysis (DMA), ASTM D5279-08 (2008)) at 50° C. of from 0.06 to 0.13.
US Pat. No. 10,392,632

AAV8 VECTOR WITH ENHANCED FUNCTIONAL ACTIVITY AND METHODS OF USE THEREOF

1. A recombinant adeno-associated virus (rAAV) vector comprising,a) capsid proteins VP1, VP2, VP3 and VP1.5
(i) of a serotype selected from the group consisting of AAV8, AAV1, AAV6 and AAV9, said VP1.5 protein translated from an ATG start codon or CTG start codon at position 10-12 of any of the nucleotide sequences of SEQ ID NOS: 5-8 of AAV8, AAV1, AAV6 and AAV9, respectively, or
(ii) of serotype AAV8, said VP1.5 protein having the sequence of SEQ ID NO:3 or SEQ ID NO:4, and
b) a viral vector genome, said genome comprising a minigene comprising AAV inverted terminal repeats and a heterologous nucleic acid sequence operably linked to regulatory sequences which direct expression of a product from the heterologous nucleic acid sequence in a host cell, wherein said rAAV vector capsid proteins package said viral vector genome and wherein said rAAV vector capsid proteins VP1, VP2, VP3, and VP1.5 are of the same serotype.
US Pat. No. 10,391,094

COMPOSITIONS AND METHODS FOR TREATING MYELOFIBROSIS

Impact Biomedicines, Inc....

8. An article of manufacture comprising:(a) a capsule comprising a formulation comprising (i) a compound that is N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide dihydrochloride monohydrate, (ii) a microcrystalline cellulose, and (iii) sodium stearyl fumarate,
wherein:
the weight ratio of N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide to microcrystalline cellulose in the formulation is about 1:1.5 to about 1:9, and
sodium stearyl fumarate is about 1% by weight of the formulation; and
(b) a package insert or a label indicating that the formulation is useful for treating myelofibrosis in a subject.
US Pat. No. 10,392,633

MULTIFUNCTIONAL ALLELES

REGENERON PHARMACEUTICALS...

1. A nucleic acid construct, comprising:(a) targeting arms for directing the nucleic acid construct to a target gene of a nucleic acid of a cell;
(b) an actuating sequence that comprises a 3? splice acceptor followed by a reporter in sense orientation with respect to transcription of the target gene;
(c) a drug selection cassette (DSC) in sense or antisense orientation;
(d) a nucleotide sequence of interest (NSI) in antisense orientation;
(e) a conditional by inversion (COIN) element in antisense orientation; and
(f) recombinable units comprising:
(i) a first pair of cognate recombinase recognition sites, R1/R1?;
(ii) a second pair of cognate recombinase recognition sites, R2/R2?;
(iii) a third pair of cognate recombinase recognition sites, R3/R3?;
(iv) a fourth pair of cognate recombinase sites, R4/R4?; and
(v) a fifth pair of cognate recombinase sites R5/R5?;
wherein R1/R1? and R3/R3? are recognized by a first recombinase, wherein R4/R4? and R5/R5? are recognized by a second recombinase, and wherein R2/R2? are recognized by a third recombinase, wherein the first, second, and third recombinases are not the same;
wherein a first recombinable unit is framed by R1 and R1? in opposite orientation, wherein between R1 and R1? are disposed: the actuating sequence; R2; the DSC; R3; R4; the NSI; and R5;
wherein a second recombinable unit is framed by recombinase sites R2 and R2? in the same orientation, wherein between R2 and R2? are disposed: the DSC; R3; R4; the NSI; R5; R1; R3? in opposite orientation with respect to R3; the COIN element; R5? in the same orientation with respect to R5; R4? in the same orientation with respect to R4;
wherein a third recombinable unit is framed by recombinase sites R3 and R3? in opposite orientation, wherein between R3 and R3? are disposed: R4; the NSI; R5; and R1;
wherein a fourth recombinable unit framed by recombinase sites R4 and R4? in the same orientation, wherein between R4 and R4? are disposed: the NSI; R5; R1; R3; the COIN element; and R5; and
wherein a fifth recombinable unit is framed by R5 and R5? in the same orientation, wherein between R5 and R5? are disposed: R1; R3; and the COIN element; wherein the recombinable units recombine upon exposure to the first recombinase to form a conditional allele that lacks the actuating sequence and the DSC, and contains the NSI in sense orientation and the COIN element in antisense orientation; and wherein the conditional allele when further exposed to the second recombinase, recombines to form an allele lacking the NSI and having the COIN element in sense orientation.
US Pat. No. 10,391,096

METHOD FOR TREATING THROMBOTIC DISORDERS USING QUERCETIN-CONTAINING COMPOSITIONS

Quercegen Pharmaceuticals...

1. A method for treating a thrombotic disorder, the method comprising administering to a subject in need thereof an effective amount of a composition that includes isoquercetin, vitamin B3, vitamin C, and folic acid, wherein the thrombotic disorder is venous thrombosis.
US Pat. No. 10,391,097

TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-ALPHA SYNTHESIS AND AS PDE4 INHIBITORS

vTv Therapeutics LLC, Hi...

1. A method of treating ankylosing spondylitis comprising administering to a human a compound, wherein the compound is selected from the group consisting of1-cyclopentyl-7-methoxy-3-(4-methyl-thiophen-2-yl)-1H-pyrimido[5,4-c]quinoline-2,4-dione,
1-cyclopentyl-7-methoxy-3-m-tolyl-1H-pyrimido[5,4-c]quinoline-2,4-dione,
3-(3-chloro-phenyl)-1-(1-methane-sulfonyl-piperidin-4-yl)-7-methoxy-1H-pyrimido[5,4-c]-quinoline-2,4-dione,
trans-4-[3-(3-chloro-phenyl)-7-methoxy-2,4-dioxo-3,4-dihydro-2H-pyrimido-[5,4-c]quinolin-1-yl]-cyclohexanecarboxylic acid methyl ester,
3-(3-chloro-phenyl)-1-((R)-1-methane-sulfonyl-pyrrolidin-3-yl)-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione,
3-(3-chloro-phenyl)-1-((S)-1-methane-sulfonyl-pyrrolidin-3-yl)-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione,
3-(3-chloro-phenyl)-1-(1-ethanesulfonyl-piperidin-4-yl)-7-methoxy-1H-pyrimido-[5,4-c]quinoline-2,4-dione, and
N-{4-[(S)-3-(3-chloro-phenyl)-7-methoxy-2,4-dioxo-3,4-dihydro-2H-pyrimido[5,4-c]quinolin-1-yl]-trans-cyclohexyl}-methanesulfonamide,
or a pharmaceutically acceptable salt thereof.
US Pat. No. 10,392,637

MICROBIAL PRODUCTION OF ALKANOLAMIDES AND AMIDOAMINES AND USES THEREOF

REG Life Sciences, LLC, ...

1. A recombinant microorganism comprising an exogenous nucleic acid sequence encoding an N-(4-amino-2-hydroxylbutyl) tetradecanamide synthase (AhtS) having at least 90% sequence identity to the amino acid sequence of SEQ ID NO: 3, wherein the AhtS catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide, and wherein the microorganism further expresses an exogenous thioesterase (EC 3.1.2.14 or EC 3.1.1.5) and is cultured in the presence of a carbon source.
US Pat. No. 10,391,612

ADDITIVE COMPOSITION AND COMPOSITION BINDING AGENT FOR SUPERHARD MATERIAL AND PREPARATION THEREOF, AND SELF-SHARPENING DIAMOND GRINDING WHEEL AND PREPARATION THEREOF

1. A method for preparing an additive for a superhard material product comprising steps of:1) mixing Bi2O3 25%˜40%, B2O3 25%˜40%, ZnO 5%˜25%, SiO2 2%˜10%, Al2O3 2%˜10%, NaCO3 1%˜5%, Li2CO3 1%˜5%, and MgCO3 0%˜5% in mass percentages, heating up to 1200˜1400° C. and keeping temperature for 1˜3 h to provide a mixture;
2) cooling the mixture obtained in Step 1) to 850˜950° C., adding CaF2 1%˜5% in mass percentages of the formula ratio and mixing, and keeping temperature for 1˜2 h to provide a sinter;
3) quenching the sinter obtained in Step 2) and then crushing the quenched sinter to have a particle size of D90<200 nm to provide the additive, wherein the additive has a microcrystalline structure.
US Pat. No. 10,392,638

METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE OVEREXPRESSING A GENE ENCODING AN IRON EXPORTER

AJINOMOTO CO., INC., Tok...

1. A method for producing an L-amino acid comprising:(i) cultivating an L-amino acid-producing bacterium of the family Enterobacteriaceae in a culture medium to produce and accumulate the L-amino acid in the culture medium, and
(ii) collecting the L-amino acid from the culture medium,
wherein said bacterium has been modified to overexpress a gene encoding an iron exporter compared to expression of said gene in the corresponding unmodified bacterium,
wherein said gene encoding an iron exporter is overexpressed by increasing the copy number of said gene, and/or modifying an expression regulatory region of said gene, so that the expression of said gene is enhanced as compared with the corresponding unmodified bacterium,
wherein said gene encoding an iron exporter encodes a protein selected from the group consisting of:
(A) a protein comprising the amino acid sequence of SEQ ID NO: 2, 4 or 6;
(B) a protein comprising the amino acid sequence of SEQ ID NO: 2, 4 or 6, but which includes substitution, deletion, insertion, and/or addition of one to ten amino acid residues, wherein said protein has an iron exporter activity; and
(C) a protein comprising an amino acid sequence that is not less than 95% identical to the entire amino acid sequence of SEQ ID NO: 2, 4 or 6, wherein said protein has an iron exporter activity.
US Pat. No. 10,391,100

COMBINATION OF AURORA KINASE INHIBITORS AND ANTI-CD20 ANTIBODIES

Millennium Pharmaceutical...

1. A method of treating a human patient suffering from a hematological malignancy, comprising administering to the human patient an Aurora kinase inhibitor, wherein the Aurora kinase inhibitor is 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acid, or a pharmaceutically acceptable salt thereof, simultaneously with or consecutively with an anti-CD20 antibody, wherein the anti-CD20 antibody is rituximab,wherein the Aurora kinase inhibitor is administered to the human patient at a dose that is equivalent to an average daily dose (QD) in a mouse of about 3 mg/kg, and the anti-CD20 antibody is administered to the human patient at a dose that is equivalent to an average weekly dose (QW) in a mouse of about 10 mg/kg.
US Pat. No. 10,392,639

PROCESS FOR THE TREATMENT OF YEAST CELL WALLS WITH A LAMINARIPENTAOSE PRODUCING BETA-1,3-GLUCANASE

DSM IP Assets B.V., Heer...

1. A process for the treatment of a composition comprising yeast cell walls comprising ?-1,3-glucans which are insoluble when extracted with water and partially soluble when extracted with dimethyl sulfoxide (DMSO), the process comprising contacting said composition with laminaripentaose-producing-?-1,3-glucanase followed by inactivating the laminaripentaose-producing-?-1,3-glucanase to result in a second composition comprising yeast cell walls wherein the second composition comprises a higher percentage of the ?-1,3-glucans relative to the total ?-1,3-glucans which are soluble in DMSO compared to the percentage of ?-1,3-glucans in untreated yeast cell walls, and wherein the ratio of the ?-1,3-glucans soluble in DMSO compared to water is greater than or equal to 2, wherein the laminaripentaose-producing-?-1,3-glucanase comprises an amino add sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ D NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 and SEQ ID NO: 7 or an amino acid sequence 70% or more identical to SEQ ID NO: 6 or SEQ ID NO: 7.
US Pat. No. 10,391,101

DERIVATIVES OF 7-FLUORO-8-CHLORO-5H-DIBENZO [B,E,] [1,4] DIAZEPINE AND USE THEREOF

VALENTEK LLC, Moscow (RU...

1. A method of treating a treatment-resistant form of schizophrenia, comprising:administering a therapeutically effective amount of a pharmaceutical composition to a subject in need thereof, wherein the pharmaceutical composition comprises an active ingredient selected from the group consisting of: (a) 11-(piperazine-1-yl)-7-fluoro-8-chloro-5H-dibenzo[b,e][1,4]diazepine; (b) 11-(4-methyl piperazine-1-yl)-7-fluoro-8-chloro-5H-dibenzo[b,e][1,4]diazepine; and (c) a pharmaceutically acceptable salt, hydrate, or solvate of (a) or (b); and
reducing one or more symptoms associated with schizophrenia, wherein said symptoms comprise symptoms of a cognitive disorder;
wherein the therapeutically effective amount comprises a daily dosage of 50 to 300 mg of the active ingredient.
US Pat. No. 10,392,640

METHOD FOR MODIFYING STARCH TO SLOW DOWN THE DIGESTION RATE

Jiangnan University, Wux...

1. A method to modify starch to slow down the digestion rate of the starch, comprising the sequential steps of:a) heating a starch slurry sample at 50 to 60° C. for 10 to 15 minutes and then adding 20 to 50 U/g starch branching enzyme (GBE) to the starch slurry sample, wherein the GBE is encoded by a GBE gene having the DNA sequence of SEQ ID NO:1;
b) incubating the starch slurry sample with the GBE at 50 to 60° C. for 4 to 20 hours;
c) heating the starch slurry sample in boiling water to obtain a gelatinized starch and inactivate the GBE;
d) incubating the gelatinized starch at 50 to 60° C. for 10 to 15 minutes and then adding 20 to 50 U/g of the GBE to the gelatinized starch;
e) incubating the gelatinized starch with the GBE at 50 to 60° C. for 4 to 20 hours;
f) heating the gelatinized starch in boiling water to terminate the enzymatic reaction; and
g) obtaining final product of modified starch after freeze-drying.
US Pat. No. 10,391,102

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS

Melt Pharmaceuticals, Inc...

1. A method for inducing conscious sedation, procedural sedation, analgesia, pre-sedation or a non-general anesthesia in a patient in need thereof, comprising administering to the patient a pharmaceutical composition comprising:(a) a therapeutically effective quantity of a first pharmaceutically active compound selected from the group consisting of midazolam, diazepam, lorazepam, flunitrazepam, alprazolam, chlordiazepoxide, clonazepam and clorazepate, and pharmaceutically acceptable salts, hydrates, solvates or N-oxides thereof;
(b) a therapeutically effective quantity of a second pharmaceutically active compound selected from the group consisting of ketamine, dextrorphan, etomidate, methadone, memantine, amantadine, dextromethorphan, and pharmaceutically acceptable salts, hydrates, solvates or N-oxides thereof;
(c) a pharmaceutically suitable binder therefor; and
(d) optionally, a pharmaceutically acceptable excipient,
wherein the pharmaceutical composition is administered by a method selected from the group consisting of rectal administration, oral spray administration, transdermal administration, and transmucosal administration, to induce conscious sedation, procedural sedation, analgesia, pre-sedation or non-general anesthesia thereby.
US Pat. No. 10,391,103

FERROPORPHYRIN SOLID DISPERSION AND PREPARATION METHOD THEREOF

SINOTHERAPEUTICS INC., S...

1. A porphyrin iron solid dispersion, comprising porphyrin iron and a carrier material, wherein said carrier material is selected from one or more of polymers comprising vinylpyrrolidone units, or mixtures thereof; polymers comprising ethylene glycol units; and celluloses or cellulose esters; wherein porphyrin iron is dispersed in said carrier material at molecular level; and wherein the weight ratio of porphyrin iron to the carrier material is 1:1 to 1:10; andwherein the porphyrin iron solid dispersion is prepared by a process including:
either feeding a homogenously mixed mixture of porphyrin iron and the carrier material at a said weight ratio, or simply feeding porphyrin iron and the carrier material at a said weight ratio, into a hot melt extruder preheated to about 120° C. to about 180° C.; and
cooling, pulverizing, and sieving the extruded mixture, to obtain the porphyrin iron solid dispersion.
US Pat. No. 10,392,642

HIGH MOLECULAR WEIGHT HEPAROSAN POLYMERS AND METHODS OF PRODUCTION AND USE THEREOF

The Board of Regents of t...

1. An isolated polynucleotide encoding a polypeptide having heparosan synthase activity, wherein at least one of: (a) the polynucleotide has the nucleotide sequence of at least one of SEQ ID NOS: 9-11; and (b) the polynucleotide is at least 95% identical to at least one of the sequences of SEQ NOS: 9-11, and wherein the polynucleotide sequences of (a) and (b) are gene-optimized for expression in a recombinant host cell.
US Pat. No. 10,396,226

MASTERBATCH FOR SOLAR BATTERY SEALING SHEET AND PROCESS FOR PRODUCING SOLAR BATTERY SEALING SHEET

SUMITOMO CHEMICAL COMPANY...

1. A process for producing a solar battery sealing sheet, comprising melt-kneading a mixture of a masterbatch and at least one ethylene resin selected from the group consisting of an ethylene-?-olefin copolymer, an ethylene homopolymer and an ethylene-unsaturated ester copolymer to obtain a melt-kneaded mixture, followed by molding the melt-kneaded mixture into a sheet, wherein the content of the masterbatch is 0.05 to 40 parts by mass with respect to 100 parts by mass of the at least one ethylene resin,wherein the masterbatch comprises:
at least one ethylene resin selected from the group consisting of an ethylene-?-olefin copolymer, an ethylene homopolymer and an ethylene-unsaturated ester copolymer and
at least one compound selected from the group consisting of silicon dioxide and zeolite,
wherein a degree of aggregation of silicon is 0 or more and 0.350 or less and
the ignition loss of the compound is more than 1.7% to 15% or less; and
the content of the at least one compound selected from the group consisting of silicon dioxide and zeolite in the masterbatch is larger than that in the solar battery sealing sheet.
US Pat. No. 10,392,643

METHODS OF USING ACYL-COA SYNTHETASE FOR BIOSYNTHETIC PRODUCTION OF ACYL-COAS

Conagen Inc., Bedford, M...

1. A biosynthetic method of making 8-methylnonenoyl-CoA comprising:expressing a heterologous acyl-CoA synthetase (ACS) in a cellular system;
feeding 8-methyl-trans-6-nonenoic acid to the cellular system;
growing the cellular system in a medium; and
producing 8-methylnonenoyl-CoA,
wherein the cellular system is bacteria or yeast, and
wherein the heterologous ACS is ghost chili pepper ACS1.
US Pat. No. 10,391,105

METHODS OF TREATING CERTAIN DEPRESSIVE DISORDERS AND DELIRIUM TREMENS

MARINUS PHARMACEUTICALS I...

1. A method of treating postpartum depression, premenstrual dysphoric disorder, menopausal depression, or delirium tremens comprising administering an effective amount of an neurosteroid formulation to a patient in need thereof; wherein the neurosteroid formulation is an ganaxolone formulation comprisinga) water;
b) sulfobutyl ether-?-cyclodextrin (CAPTISOL) and ganaxalone, wherein the ratio of sulfobutyl ether-?-cyclodextrin to ganaxolone wherein weight to weight (w/w) ratio of sulfobutyl ether-?-cyclodextrin is about 52:1 or greater; and
c) a buffer, the formulation having a pH of 6.8 to 7.6.
US Pat. No. 10,392,644

PRODUCTION OF STEVIOL GLYCOSIDES IN MICROORGANISMS

EVOLVA SA, Reinach (CH)

1. A recombinant host cell capable of producing steviol, a target steviol glycoside or a target steviol glycoside composition, comprising:(a) a gene encoding a polypeptide capable of beta 1,2 glycosylation of the C2? of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of a precursor steviol glycoside and having at least 95% sequence identity to the amino acid sequence set forth in SEQ ID NO:5;
wherein the polypeptide is capable of transferring a sugar moiety to the C2? of a glucose in the precursor steviol glycoside;
and one or more of:
(b) a gene encoding a polypeptide capable of glycosylating steviol or the precursor steviol glycoside at its C-13 hydroxyl group; and/or
(c) a gene encoding a polypeptide capable of beta 1,3 glycosylation of the C3? of the 13-O-glucose of the precursor steviol glycoside; and/or
(d) a gene encoding a polypeptide capable of glycosylating steviol or the precursor steviol glycoside at its C-19 carboxyl group;
wherein at least one of the genes is a recombinant gene.
US Pat. No. 10,393,412

CRYOCOOLER REGENERATOR MATERIAL, CRYOGENIC REGENERATOR, REGENERATIVE CRYOCOOLER AND SYSTEM COMPRISING REGENERATIVE CRYOCOOLER

KABUSHIKI KAISHA TOSHIBA,...

1. A cryogenic regenerator, which is filled with a cryogenic regenerator material containing as a main constituent at least one compound (A), wherein a half width of a main peak obtained by a powder X-ray diffraction measurement on the compound (A) is 0.2 degrees or more,wherein said at least one compound (A) is represented by a composition formula Ma2X or MbW2X8,
wherein, in the composition formulae,
Ma represents a metallic element selected from Cu, Ag, Au, Pd and Pt, or two or more metallic elements comprising at least one selected from Cu, Ag, Au, Pd and Pt as the main constituent element,
Mb represents a metallic element selected from Zr and Hf, or two or more metallic elements comprising at least one selected from Zr and Hf as the main constituent element, and
X represents at least one non-metallic element selected from O, S and N.
US Pat. No. 10,396,228

QUANTUM DOT AND LUMINESCENT MATERIAL MADE THEREFROM

OSRAM Opto Semiconductors...

1. A quantum dot, comprising:a nanocrystalline core comprising a first semiconductor material; and
one or more nanocrystalline shells comprising a second, different, semiconductor material at least partially surrounding the nanocrystalline core, wherein an absorption spectrum and an emission spectrum of the quantum dot are essentially non-overlapping.