US Pat. No. 10,189,398

LASER HEAD LAMP FOR VEHICLE AND VEHICLE

LG Electronics Inc., Seo...

1. A laser head lamp for a vehicle, comprising:a plurality of lamp modules each comprising a laser diode and configured to output at least one of a low beam or a high beam;
at least one processor; and
a computer-readable medium coupled to the at least one processor having stored thereon instructions which, when executed by the at least one processor, causes the at least one processor to perform operations comprising:
acquiring total operation time of each of the plurality of lamp modules; and
controlling, based on the acquired total operation times, at least one first lamp module among the plurality of lamp modules differently from at least one second lamp module among the plurality of lamp modules.

US Pat. No. 10,189,396

VEHICLE HEADLAMP CONTROL DEVICE

TOYOTA JIDOSHA KABUSHIKI ...

1. A vehicle headlamp control device comprising:a headlamp that irradiates an area in front of a vehicle;
a camera that captures an image of the area in front of the vehicle;
a pedestrian detection portion configured to detect a pedestrian in front of the vehicle from the image captured by the camera by performing pattern recognition based on a plurality of preregistered pattern images, wherein an image of a pedestrian whose eyes are hidden by a given-shaped part is included in the plurality of preregistered pattern images; and
a control portion configured to control the headlamp and cause the headlamp to irradiate the pedestrian based on the preregistered pattern image of the pedestrian whose eyes are hidden by the given-shaped part, so that the given-shaped part formed at a location of an eye of the pedestrian is not irradiated, or is irradiated by dimmed light.

US Pat. No. 10,189,395

ROTATABLE LIGHT BAR FOR MOTOR VEHICLE SPORT BARS

Iddea California, LLC, B...

1. A light bar and mounting system for a motor vehicle, comprising:a generally rectangular support frame encircling an elongated support member, the support frame having two opposing sidewalls joined to two opposing, first and second ends and open top;
a rotational axis extending between the first and second ends with the elongated support member extending along and rotating about that axis between a first, retracted position and a second, deployed position;
a plurality of electrical lights fastened to the elongated support member and pointing in the same direction and rotating with the elongated support member between the first and second positions, the plurality of lights in the first position pointing along a generally vertical axis during use and in the second position pointing in a direction generally perpendicular to the first direction;
an actuating mechanism having a piston connected to the elongated support member at a location offset from the rotational axis to form an offset cam, the actuating member is movable between a first, retracted cam position which rotates the elongated support member and lights to the first, retracted position, and a second, deployed cam position which rotates the elongated support member and lights to the second, deployed position;
a first mounting bracket having a first, upper end connected to at least one of the first end of the support frame or one of the sides of the support frame, the first mounting bracket having a second, lower end with a mounting plate to connect to the vehicle during use;
a second mounting bracket having a first, upper end connected to at least one of the second end of the support frame or one of the sides of the support frame, the second mounting bracket having a second, lower end with a mounting plate to connect to the vehicle during use.

US Pat. No. 10,189,394

VEHICLE GUTTER SPOUT COVER

1. A vehicle gutter spout cover comprising:a first receptacle with a generally smooth outside surface;
a first orifice located on the first receptacle and configured to allow the first receptacle to slide over and enclose at least a portion of a gutter spout;
an adjustable length connecting means permanently attached to the first receptacle, the adjustable length connecting means comprising:
a first connector;
a first connector length adjustment means attached to the first connector;
a second connector attached to the first connector length adjustment means, and wherein the adjustable length connecting means is infinitely adjustable in length between a maximum length and minimum length;
a second receptacle with a generally smooth outside surface;
a second orifice located on the second receptacle and configured to allow the second receptacle to slide over and enclose at least a portion of a gutter spout, and the adjustable length connecting means permanently attached to the second receptacle, and
wherein the adjustable length connecting means is configured to be tightened to securely attach the first receptacle and second receptacle to the gutter spouts.

US Pat. No. 10,189,393

METHOD AND SYSTEM FOR OPERATING A TIPPER

Hyva Holding B.V., Alphe...

1. A method of operating a tipper comprising a tipper body pivotably moveable with respect to a frame with a hydraulic cylinder disposed therebetween which can be actuated by a hydraulic actuation system to pivot the tipper body, the method comprising:receiving at least one lateral state parameter relating to at least one lateral state of the hydraulic cylinder;
determining whether a lateral condition of the hydraulic cylinder is within acceptable limits based on the at least one lateral state parameter; and
altering, or permitting the alteration of, at least one operational parameter of the hydraulic actuation system if it is determined that the lateral condition of the hydraulic cylinder is within acceptable limits.

US Pat. No. 10,189,363

ELECTRIC VEHICLE ROADWAY CHARGING SYSTEM AND METHOD OF USE

NIO USA, Inc., San Jose,...

1. A system for charging an electric vehicle comprising:an electrical storage unit disposed on an electric vehicle;
a power source disposed external to the electric vehicle and configured to charge the electrical storage unit;
a charging panel in electrical communication with the electrical storage unit;
a vehicle database comprising required conditions for deployment of the charging panel; and
a vehicle controller that determines if the electrical storage unit requires charging and when the electrical storage unit is determined to require charging, the vehicle controller determines if conditions allow for deployment of the charging panel, wherein determining if conditions allow for deployment include the vehicle controller querying the vehicle database for the required conditions for deployment of the charging panel, the required conditions including information on charging services associated with a particular roadway the electric vehicle is on;
wherein the charging panel receives the charge from the power source and charges the electrical storage unit.

US Pat. No. 10,189,345

CONTROL OF INTERNAL COMBUSTION ENGINE AND ROTATING ELECTRICAL MACHINE FOR VEHICLE

HONDA MOTOR CO., LTD., T...

1. A vehicle comprising:an internal combustion engine;
a transmission;
a clutch interposed between the internal combustion engine and the transmission;
a first rotating electrical machine connected to a first wheel via the clutch;
a second rotating electrical machine connected to a second wheel or the first wheel without going through the clutch;
an electric power storage device that supplies electric power to the first rotating electrical machine and the second rotating electrical machine; and
a power controller that controls power of the internal combustion engine, the first rotating electrical machine, and the second rotating electrical machine,
wherein the power controller, when adding additional power to the power of the internal combustion engine, allocates the electric power to the second rotating electrical machine with priority over the first rotating electrical machine to generate power by the second rotating electrical machine with priority over the first rotating electrical machine,
wherein the power controller controls the power of the internal combustion engine and the second rotating electrical machine such that sum of the power of the internal combustion engine and the power of the second rotating electrical machine exceeds maximum transmission power of the clutch.

US Pat. No. 10,189,283

VACUUM MEDIA TRANSPORT SYSTEM WITH REDUCED PRESSURE VARIATIONS IN INTER-COPY GAPS

Xerox Corporation, Norwa...

1. A media transport system comprising:a vacuum plenum; and
a belt positioned over the vacuum plenum, the belt comprising:
at least one member configured to carry print media in a process direction;
a first plurality of holes formed through the at least one member in a first region only that carries a first print medium to enable the vacuum plenum to apply a force to hold the first print medium against the at least one member of the belt;
a second plurality of holes formed through the at least one member in a second region only that carries a second print medium to enable the vacuum plenum to apply the force to hold the second print medium against the at least one member of the belt; and
a plurality of slots formed through the at least one member in a third region corresponding to an inter-copy gap only that is positioned between the first region and the second region, each slot in the plurality of slots being formed with a first area that is greater than a second area occupied by one hole in the first plurality of holes or the second plurality of holes wherein the plurality of slots is arranged with a length of each slot being aligned with the process direction of the belt.

US Pat. No. 10,189,231

FABRIC HAVING A WATERPROOF BARRIER

Columbia Sportswear North...

1. An article of clothing, body gear, sporting gear, gloves, headwear, or footwear, comprising:a base material having an inward-facing surface and an outward-facing surface;
an exposed, breathable, hydrophobic, waterproof barrier disposed on the outward-facing surface of the base material, the waterproof barrier having an exposed, outward-facing surface and an inward-facing surface directed toward the base material;
a seam running through the waterproof barrier; and
a waterproof tape bonded to the outward-facing surface of the waterproof barrier and oriented to seal the seam against water ingress.

US Pat. No. 10,188,821

OXYGEN CONCENTRATION DEVICE

Teijin Pharma Limited, T...

1. An oxygen concentration device which generates oxygen-enriched gas, comprising: adsorbent cylinders packed with an adsorbent which preferentially adsorbs nitrogen rather than oxygen; a compressor which supplies compressed air to the adsorbent cylinders; a flow path switching valve for switching between a flow path between the compressor and the adsorbent cylinders and a flow path between the adsorbent cylinders and an exhaust pipe for discharging desorbed gas to outside of the system in order to repeat at a fixed timing an adsorption step in which compressed air is supplied to the adsorption cylinders and nitrogen in the compressed air is adsorbed to generate unadsorbed oxygen, a desorption step in which the adsorption cylinders are purged under reduced pressure to desorb the nitrogen and regenerate the adsorbent, and a pressure equalization step in which an adsorbent cylinder after completion of the adsorption step and an adsorption cylinder after completion of the desorption step are connected to each other to equalize pressure of the two cylinders; and a pressure equalization valve provided on a pressure equalization path which connects between the adsorbent cylinders, wherein a pressure control member having a difference in pressure loss due to the direction of gas flow is provided at at least one end side of the pressure equalization valve so that pressure loss of gas which flows through the pressure equalization path in one direction becomes nearly equal to that of the gas which flows therethrough in the opposite direction.

US Pat. No. 10,188,819

MOTION STABILIZER SYSTEM FOR RESPIRATORY INTERFACE DEVICE

KONINKLIJKE PHILIPS N.V.,...

1. A respiratory interface device comprising:a patient interface device including a body, the patient interface device body including an outer side;
a support assembly including a frame body, the frame body defining an opening, wherein, when the patient interface assembly is in use, the frame body opening is generally disposed in front of a user's nose;
the patient interface device body outer side disposed adjacent the frame body opening; and
an elastic coupling assembly including a number of elastic bands, each elastic band including a first end and a second end, wherein each elastic band first end is coupled to the frame body adjacent the frame body opening, wherein each elastic band second end is coupled to the patient interface device body outer side, and wherein the patient interface device body is floatably coupled to the frame body.

US Pat. No. 10,188,799

AUTOINJECTOR

APTAR FRANCE SAS, Le Neu...

1. An autoinjector comprising a body that is adapted to receive a reservoir (S), said reservoir (S) containing fluid and including a piston (P) and a needle (A), said autoinjector further comprising an actuator sleeve that includes a contact end for coming into contact with a user's body, said actuator sleeve extending inside said body at least in part, and being movable relative to said body between projecting positions in which said actuator sleeve projects out from said body at least in part, and an actuated position in which said actuator sleeve is moved axially into said body, said actuator sleeve being in a first projecting position before actuation of the autoinjector, and in a second projecting position after actuation of the autoinjector; and wherein:said actuator sleeve, in said second projecting position, extends axially further out from said body than in said first projecting position, said actuator sleeve including an annular zone that, in said first projecting position, is arranged inside said body and that, in said second projecting position, is arranged outside said body, said annular zone including a visual indicator for indicating to the user that the autoinjector has been actuated;
and, axially adjacent to said annular zone, said actuator sleeve includes an outwardly-projecting radial shoulder, said shoulder projecting radially outwards relative to said visual indicator, thereby protecting said visual indicator against any contact with an inside surface of the body while the actuator sleeve is moving in said body, a bottom end of the actuator sleeve, that comes into contact with a zone in which injection takes place, comprising an outwardly-projecting radial shoulder that projects radially outwards relative to said visual indicator and that is distinct from the outwardly-projecting radial shoulder that is axially adjacent to said annular zone.

US Pat. No. 10,188,794

CLOSED LOOP CONTROL AND SIGNAL ATTENUATION DETECTION

Abbott Diabetes Care Inc....

1. A method, comprising:monitoring a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and automatic administration of a medication;
detecting a signal level associated with the monitored physiological condition deviating from a predetermined threshold level;
retrieving a medication level administered associated with a time period of the detected signal level;
applying the retrieved medication level to the detected signal level based on a predefined predictive model to generate a predictive signal; and
comparing the detected signal level to the predictive signal to determine whether a condition associated with the detected signal level is present.

US Pat. No. 10,188,792

AUTOMATED PRESSURE LIMIT SETTING METHOD AND APPARATUS

CareFusion 303, Inc., Sa...

1. A fluid pump, comprising:a pressure sensor for sensing fluid pressure during an infusion of a fluid;
a display;
a memory; and
a processor coupled with the memory and the display, the memory storing program code that, when executed by the processor causes the processor to:
receive an identity of an infusion tubing connector or an infusion vascular access device used for the infusion of the fluid;
receive values of one or more infusion parameters;
calculate, based on the received identity and the received infusion parameter values, an occlusion pressure threshold for the infusion of the fluid;
receive, during the infusion, a fluid pressure signal from the pressure sensor; and
provide an indication responsive to whether a value of the received fluid pressure signal contravenes the occlusion pressure threshold.

US Pat. No. 10,188,784

APPARATUS WITH RIGID MEMBER FOR SENSING FLUID PRESSURE

FENWAL, INC., Lake Zuric...

1. A blood processing system, comprising:a first housing configured to be reused for multiple blood processing operations for different donors;
a second housing configured for a single blood processing operation, the second housing insertable to and removable from the first housing, the second housing comprising a conduit configured to house blood and a pressure sensing portion having a rigid member disposed thereon, the rigid member configured to move in response to a change in pressure of the blood; and
a sensor system coupled to the first housing and configured to be reused for multiple blood processing operations, the sensor system comprising a second member and a sensor, the second member removeably coupled to the rigid member, the sensor configured to detect across an air gap movement of the second member and to generate a signal indicative of the movement.

US Pat. No. 10,188,782

BLOOD PROCESSING FILTER AND BLOOD PROCESSING METHOD

ASAHI KASEI MEDICAL CO., ...

21. A blood processing method using a blood processing filter, the filter comprising:a sheet-shaped filter element;
an inlet-side flexible container and an outlet-side flexible container that sandwich the filter element;
an inlet port that is provided at the inlet-side flexible container and receives unprocessed blood; and
an outlet port that is provided at the outlet-side flexible container and discharges the blood processed by the filter element, the filter further comprising:
a flow path securing sheet disposed between the filter element and the outlet-side flexible container;
a belt-shaped first seal portion that seals at least the filter element and the flow path securing sheet, and is provided so as to be apart from the outlet-side flexible container; and
an annular second seal portion that seals at least the inlet-side flexible container and the outlet-side flexible container, and is provided so as to surround the filter element and the flow path securing sheet,
wherein the first seal portion includes a pair of lateral portions disposed opposite to each other with the outlet port interposed therebetween, and a communication portion connected to the pair of lateral portions, the communication portion includes a lower side portion and an upper side portion, the flow path securing sheet includes ribs consisting of only a pair of ribs that are disposed between the pair of lateral portions and opposite to each other with the outlet port interposed therebetween, a slit disposed between the pair of ribs to communicate with a concave portion formed of the communication portion, and diffusing openings that are disposed outside of the pair of ribs and continuously open from the ribs to the lateral portions and communicate with the concave portion formed of the lateral portions, and continuously open from the lower side portion to the upper side portion, and the width of each of the diffusing openings is 20 to 30 mm.

US Pat. No. 10,188,781

METHOD OF MANUFACTURING HEAT EXCHANGER AND HEAT EXCHANGER

TERUMO KABUSHIKI KAISHA, ...

1. A method of manufacturing a heat exchanger having a hollow fiber membrane layer and comprised of a plurality of hollow fiber membrane conduits each of which has a hollow portion allowing a heat medium to pass therethrough, the method comprising the steps of:providing a cylindrical body for supporting the fiber membrane layer, wherein the cylindrical body has an outer surface defining a longitudinal axis and first and second longitudinal ends;
winding a continuous base cord of hollow fiber membrane onto the cylindrical body along a generally helical trajectory around the longitudinal axis with a plurality of continuous round trips from the first end to the second end and turning back at each respective end, wherein each round trip completes a number of circumferential revolutions N, wherein N is greater than or equal to one, wherein N is less than two, wherein an inclination angle of the hollow fiber membrane between turning-back portions ranges from 40° to 70°, and wherein each turning-back portion is folded at an acute angle;
continuously fixing in place each respective turning-back portion at the first end and the second end during the winding of the base cord;
cutting longitudinal end portions from the fiber membrane layer, thereby removing the turning-back portions to introduce open ends for the hollow fiber membrane conduits;
wherein the winding step satisfies an expression Traverse [mm/rotation]×N=traverse oscillation width×2±(outer diameter of hollow fiber membrane+gap between hollow fiber membranes adjacent to each other)×total number of hollow fiber membranes (where N satisfies 1?N<2).

US Pat. No. 10,188,780

BLOOD OXYGENATOR

University of Maryland, B...

14. A method for oxygenating blood through a blood oxygenator, comprising:receiving a stream of blood through an inlet and directing said stream into a spiral volute defining an internal cavity, said internal cavity decreasing in width from a first end of said spiral volute to a second end of said spiral volute, and being configured to uniformly distribute blood to an outer surface of an oxygenator fiber bundle;
wherein the blood moves from said spiral volute through the oxygenator fiber bundle and into a central lumen and is oxygenated as it moves through the oxygenator fiber bundle and into the central lumen; and
discharging the blood through a blood outlet connected to said central lumen.

US Pat. No. 10,188,577

ELASTIC FORCE GENERATING DEVICE

Honda Motor Co., Ltd., T...

1. An elastic force generating device comprising:an elastic structure which is comprising of a multilayer construction formed by alternately stacking a plurality of elastic members, each elastic member of the plurality of elastic members incorporates one or more hermetically sealed air chambers, with each hermetically sealed air chamber of the one or more hermetically sealed air chambers having a volume that decreases by compression, and a plurality of partition plates having higher stiffness than that of the elastic members, the elastic structure has through holes extending in a stacking direction and a total length in the stacking direction that is greater than a minimum width of each of the elastic members in a direction orthogonal to the stacking direction;
a flexible lengthy member inserted in a particular through hole of the through holes of the elastic structure; and
a tension imparting mechanism which is a mechanism adapted to variably impart a tension to the flexible lengthy member, the tension imparting mechanism is adapted to transmit a force between the flexible lengthy member and the elastic structure such that, at a time of imparting a tension to the flexible lengthy member, a force for compressing the elastic structure in the stacking direction increases as the tension increases.

US Pat. No. 10,188,482

CLEANING DEVICE FOR ENTERAL FEEDING CONNECTION

1. A cleaning device, comprising:a handle having a proximal end and a distal end;
a cleaning fitment attached to the distal end;
a centering post formed from a compressible polymer deformable to temporarily plug a main fluid pathway lumen of an enteral feeding connector, the centering post oriented along a longitudinal length of the cleaning device and extending from a distal end of the cleaning fitment in a fixed position relative to the cleaning fitment;
a plurality of cleaning elements extending from the fitment disposed in a spaced apart relation and extending along the longitudinal axis of the cleaning device.

US Pat. No. 10,188,462

IMAGE-GUIDED THERAPY OF A TISSUE

MONTERIS MEDICAL CORPORAT...

1. A method for effecting thermal therapy using an in vivo probe, comprising:positioning the probe in a volume in a patient;
identifying a three-dimensional region of interest at which to apply thermal therapy;
identifying, by processing circuitry, a treatment profile for effecting thermal therapy to the three-dimensional region of interest,
wherein the treatment profile comprises a plurality of target positions,
wherein each target position of the plurality of target positions is associated with one or more of a respective power level, a respective energy level, a respective emission pattern, a respective time period, and a respective geometry of a target area of the three-dimensional region of interest, and identifying the treatment profile comprises calculating the plurality of target positions as a sequence of positions and alignments of the probe based on a symmetric or asymmetric output pattern of the probe and selecting for the treatment profile a selected sequence corresponding to at least one of a minimum number of positions of the probe, and a minimum treatment time for effecting the thermal therapy to the three-dimensional region of interest based on expected output of the probe,
wherein a desired trajectory of the probe is selected so as not to interfere with imaging equipment prior to the insertion of the probe into the volume; and
applying, by the processing circuitry, thermal therapy to the volume using the probe according to the treatment profile, wherein applying the thermal therapy comprises
a) activating delivery of therapeutic energy by the probe to the three-dimensional region of interest at a first target position of the plurality of target positions according to the treatment profile,
b) causing actuation of the probe to adjust at least one of a linear position and a rotational position of the probe to a next target position of the plurality of target positions in accordance with the sequence of positions and alignments of the probe for each of the plurality of target positions in the treatment profile,
c) activating delivery of therapeutic energy to the three-dimensional region of interest at the next target position according to the treatment profile, and
d) repeating steps (b) and (c) until therapeutic energy is delivered to at least a first volume of the three-dimensional region of interest.

US Pat. No. 10,188,444

SKIN PROTECTION FOR SUBDERMAL CRYOGENIC REMODELING FOR COSMETIC AND OTHER TREATMENTS

MyoScience, Inc., Fremon...

1. An apparatus for cryogenically treating tissue, the apparatus comprising:a housing having a proximal and distal end, the housing including a heat source;
at least one needle probe extending from the distal end of the housing and comprising at least one elongate needle having a distal needle shaft portion and a proximal needle shaft portion, wherein the proximal needle shaft portion is more conductive than the distal needle shaft portion, wherein the proximal needle shaft portion extends axially along a longitudinal axis of the at least one elongate needle, and wherein the at least one elongate needle comprises a first conductive material at the distal needle shaft portion and a second conductive material at the proximal needle shaft portion conductively coupled to the first conductive material, the at least one elongate needle configured to be advanced into non-target tissue layered above target tissue such that the first conductive material at the distal needle shaft portion is positioned within and in contact with the target tissue and the second conductive material at the proximal needle shaft portion is positioned within and in contract with the non-target tissue; and
a cooling supply tube internally housed within the at least one elongate needle, wherein the cooling supply tube includes an exit within the at least one elongate needle.

US Pat. No. 10,188,438

BONE PLATE WITH TRANSVERSAL SLOTS FOR RECEIVING A FASTENER

SKELETAL DYNAMICS, LLC, ...

1. A bone plate assembly comprising:a substantially rigid plate including a first elongated slot oriented along a first, longitudinal, axis;
a slider, longitudinally displaceable along said first elongated slot;
said slider being disposed entirely within said first elongated slot;
said slider including a second elongated slot oriented along a second axis that is transverse to the first longitudinal axis;
a fastener;
wherein said fastener is configured to be simultaneously inserted through said first elongated slot and said second elongated slot and loosely engaged to an underlying bone such that said plate can be repositioned proximally and/or distally along said first longitudinal axis, laterally skewed along said second axis and circularly rotated around said fastener.

US Pat. No. 10,188,296

WIRELESS PATIENT MONITORING DEVICE

Masimo Corporation, Irvi...

1. A method of wirelessly monitoring physiological information, the method comprising:providing a battery including a data storage component;
connecting the battery to a bedside monitor;
recharging the battery via the bedside monitor;
upon connecting the battery to the bedside monitor, transferring wireless communication configuration data from the bedside monitor to the data storage component via a hard wired connection;
disconnecting the battery from the bedside monitor;
connecting the disconnected battery to a wireless monitor;
powering the wireless monitor with the battery;
upon connecting the disconnected battery to the wireless monitor, transferring the wireless communication configuration data from the data storage component to the wireless monitor;
reconfiguring wireless communication parameters of the wireless monitor according to the wireless communication configuration data when the battery is connected to the wireless monitor;
establishing wireless communication between the wireless monitor and the bedside monitor using the wireless communication configuration data;
obtaining physiological information from one or more optical sensors using the wireless monitor powered by the battery; and
transmitting physiological data reflective of the physiological information from the wireless monitor to the bedside monitor.

US Pat. No. 10,188,255

ROBOT CLEANER AND ROBOT CLEANER SYSTEM INCLUDING THE SAME

SAMSUNG ELECTRONICS CO., ...

1. A robot cleaner configured to clean a floor surface while moving on the floor surface, the robot cleaner comprising:a module mounting unit on which at least one module capable of performing a function other than cleaning is able to be mounted, and
a plurality of ports,
wherein:
at the module mounting unit, an opening is formed and provided at one side of a housing that forms an exterior of the robot cleaner,
at the module mounting unit, fixing devices configured to fix the at least one module inserted into the module mounting unit are disposed, and the fixing devices comprise:
a first fixing device including a rectangular frame; and
a second fixing device including a circular frame,
a connection unit connected to at least one of the plurality of ports is disposed at the at least one module, and
a function of the at least one module is recognized in accordance with at least one of positions and a number of the positions at which the connection unit is connected to the at least one of the plurality of ports.

US Pat. No. 10,188,247

UPRIGHT VACUUM CLEANER

JIANGSU MIDEA CLEANING AP...

1. An upright vacuum cleaner, comprising:a brushroll;
a motor assembly comprising a motor housing and a motor disposed within the motor housing, wherein a rotating axis of the motor and a rotating axis of the brushroll are disposed in a non-parallel manner, and the motor drives the brushroll to roll via a drive belt and is rotatable between a first upright position wherein the drive belt is tensioned and a first oblique position wherein the drive belt is released;
a body assembly comprising a body, a bridging member mounted to the body and rotatably connected with the motor housing to make the body rotatable between a second upright position and a second oblique position, and a dirt cup mounted to the body;
wherein the motor is moved from the first oblique position to the first upright position by the bridging member when the body moves from the second upright position to the second oblique position.

US Pat. No. 10,188,205

STRUCTURAL ELEMENT

1. A structural furniture element, having at least one frame which comprises four frame elements (101, 102, 103), whereineach said frame element (101, 102, 103) has at least one limb (V) extending from top to bottom
one or more struts (L1, L2) extend from the limb (V) of a first frame element (101, 102, 103) to a limb (V) of a second frame element (101 102, 103), with each said strut (L1, L2) having an upper side inclined relative to a horizontal,
additionally comprising a hinge (31), with the frame elements (101, 102, 103) each being fixedly connected to the hinge (31) and positionable at different angles relative to one another by the hinge (31),
the structural furniture element has opposite first and second sides, and
at least one or more first struts (L1, L2) is located on the first side and one or more second, struts (L1, L2) is located on the second side, with the oppositely-positioned first and second struts (L1, L2) being positioned such that the upper sides thereof are inclined downwardly to the horizontal and toward the inner side of the structural furniture element.

US Pat. No. 10,188,200

MODULAR DESIGNED POOL CLEANING TOOL

1. A modularly designed cleaning tool, comprising:a brush head comprising an elongate frame and bristles extending therefrom, said elongate frame having an upper surface, a lower surface, and two sidewalls extending therebetween, wherein the elongate frame comprises:
a middle portion;
a first distal portion connected to the middle portion; and
a second distal portion connected to the middle portion opposite the first distal portion,
wherein the first distal portion and the second distal portion extend from the middle portion at a first angle and a second angle, respectively, such that the lower surface at the first and second distal portions are angled relative to the lower surface at the middle portion,
wherein the distal ends of the bristles together form a cleaning surface along the middle portion and the first and second distal portions of the elongate frame;
a stem assembly having a tubular configuration and extending outwardly from the brush head at an angle from the bristles, wherein the stem assembly and the brush head define a neck area,
wherein the bristles extend from the lower surface at the middle portion such that the cleaning surface extends substantially perpendicular to the stem assembly along the middle portion, and wherein the bristles extend from the lower surface at the first and second distal portions such that the cleaning surface along the first and second distal portions is angled relative to the cleaning surface along the middle portion;
removable corner brushes each having a proximal end and a distal end, an upwardly curved surface near the distal end, the removable corner brushes each configured to receive the first or second distal portion of the elongate frame so that the removable corner brushes are detachably connected to the elongate frame,
wherein the removable corner brushes comprise bristles extending generally away from the upwardly curved surface of the removable corner brushes in a manner such that bristles adjacent the distal end of the removable corner brushes extend outwardly at an angle different from the angle which bristles disposed at the first and second distal portions of the elongate frame extend to form an additional cleaning surface at the removable corner brushes, with the removable corner brushes on the elongate frame, and
wherein the upwardly curved surface is angled relative to the corresponding lower surface at the first or second distal portion of the elongate frame with the associated removable corner brush on the elongate frame, such that the lower surface at the middle portion extends at a first angle relative to the stem assembly, the lower surface at the first and second distal portions extends at a second angle relative to the stem assembly, and the upwardly curved surface extends a third angle relative to the stem assembly, wherein the first, second, and third angles are different angles relative to the stem assembly; and
at least one magnetic component disposed on an exterior surface of the removable corner brushes such that the magnetic component is positioned adjacent a front of the brush head, said magnetic component positioned to pick up magnetic debris in water in a manner such that the magnetic debris does not adhere to the cleaning surface.

US Pat. No. 10,188,143

DISPLAY PACKAGES, BLANKS FOR FORMING TRAP SEAL CARD AND BLANK FOR FORMING DISPLAY BOX

Altria Client Services LL...

1. A display package, comprising:a first packaging including a first compartment configured to hold a first item;
a second packaging including a second compartment configured to hold a second item; and
a trap seal card including a first opening, the trap seal card retaining the first packaging and the second packaging such that
the first item and the second item to be held within the first compartment and the second compartment are visible to a consumer through the first opening, and
a portion of each of the first packaging and the second packaging protrudes through the first opening,
the trap seal card including a front panel integral with a back panel, the front panel consisting essentially of,
a first panel including the first opening, and
second, third and fourth panels, collectively, forming a third compartment in conjunction with the back panel, the third compartment protruding from a surface of the back panel, and
a portion of each of the first packaging and the second packaging being interposed between the front panel and the back panel.

US Pat. No. 10,188,050

VOLUMETRIC BUDGET BASED IRRIGATION CONTROL

Rain Bird Corporation, A...

1. A method of controlling irrigation, the method comprising:receiving water usage information corresponding to a first volumetric water usage at a site location having an irrigation controller configured to implement and control irrigation at the site and comprising valve drivers each configured to activate one or more valves distributed through the site location and an irrigation controller processor configured to implement an irrigation schedule stored in local memory of the irrigation controller, wherein the first volumetric water usage corresponds to volumetric water usage from a beginning of a budget period of time to a first time within the budget period of time;
determining automatically whether a volumetric water budget at the site location will be met for the budget period of time based on at least the first volumetric water usage, the volumetric water budget corresponding to a specified volume of water for use during the budget period of time;
determining automatically, in the event the volumetric water budget will not be met, an adjustment to the irrigation by the irrigation controller, wherein the adjustment comprises a reduction of runtimes of remaining irrigation events scheduled to occur during the budget period of time such that the adjustment substantially spreads a compensation for an amount of water usage that will exceed the volumetric water budget over the remaining irrigation events; and
outputting signaling causing the irrigation controller to control the valve drivers of the irrigation controller to control opening and closing of one or more of the valves at the site location coupled with the irrigation controller in controlling water released through water delivery devices fluidly coupled with a corresponding one of the valves in controlling irrigation at the irrigation site to effect the adjustment.
US Pat. No. 10,189,932

THERMOPLASTIC MOLDING COMPOUNDS WITH AN OPTIMIZED RESIDUAL MONOMER CONTENT

INEOS STYROLUTION GROUP G...

1. A process for the production of styrene graft copolymers comprising the following steps:(i) provision and agglomeration of the graft base B present in an emulsion;
(ii) addition of styrene monomers A1 and vinyl cyanide monomers A2 to the graft base B over a defined monomer feed time; and
(iii) simultaneous graft copolymerization of the added styrene monomers A1 and of the vinyl cyanide monomers A2 onto the agglomerated graft base B,
where, in step (ii), the ratio by mass of styrene monomers A1 to vinyl cyanide monomers A2 in the monomer feed at the end of the monomer feed time is lower than the ratio by mass of the components of the monomer feed integrated over the entire monomer feed time,
where step (iii) is followed by the following step (iv), which comprises:
(iv) addition of vinyl cyanide monomers A2 and graft copolymerization of these onto the agglomerated graft base B, where no styrene monomers A1 are added.
US Pat. No. 10,188,139

ADDITIVES FOR TOBACCO CUT FILLER

Philip Morris USA Inc., ...

1. A method of reducing cytotoxicity and/or mutagenicity in tobacco smoke is provided comprising:applying a solution comprising a mixture of glycerin and a magnesium or calcium salt selected from the group consisting of magnesium nitrate, magnesium chloride, magnesium acetate, magnesium sulfate, calcium nitrate, calcium chloride, calcium acetate and mixtures thereof, onto tobacco cut filler to form a tobacco smoking mixture capable of producing tobacco smoke when burned;
forming a smoking article comprising a wrapper, the tobacco smoking mixture and a filter; and
burning the smoking article to produce tobacco smoke with reduced cytotoxicity and/or mutagenicity;
wherein the glycerin is present in an amount of about 8 to about 13% by weight of the tobacco smoking mixture, and wherein the mixture of glycerin and magnesium or calcium salt is present in an amount effective to reduce the cytotoxicity and/or the mutagenicity of the smoke produced from the tobacco smoking mixture upon burning.
US Pat. No. 10,188,908

POLYAMIDE COMPOSITIONS CONTAINING PLASTICIZERS FOR USE IN MAKING GOLF BALLS

Acushnet Company, Fairha...

1. A golf ball, comprising:a) a core comprising an inner core and outer core layer, the inner core having an outer surface and geometric center and the outer core layer having an outer surface and inner surface; the inner core comprising a polyamide composition and the outer core layer comprising a rubber composition the polyamide composition comprising:
i) about 40 to about 90% by weight polyamide; and
ii) about 10 to about 60% by weight of a plasticizer selected from the group consisting of ethyl oleate and propylene carbonate and blends thereof, the polyamide comprising a blend of transparent and non-transparent polyamides, wherein at least one of the transparent polyamides is a polyether-amide block copolymer, and wherein the center of the inner core and surface of the outer core layer each has a hardness, and the surface hardness of the outer core layer is greater than the center hardness of the inner core; and
b) a cover having at least one layer disposed about the core.
US Pat. No. 10,189,934

PREPARATION OF MOLECULARLY IMPRINTED POLYMERS

MIP DIAGNOSTICS LIMITED, ...

1. A process for the preparation of a solution or colloidal suspension of molecularly imprinted polymer (“MIP”) particles comprising the steps of:(a) providing a carrier substance having a template material immobilized on it so the template is exposed at the carrier substance surface;
(b) providing a polymerizable composition in contact with said template;
(c) effecting controlled polymerization of said polymerizable composition in contact with said template by using a method selected from radical polymerization, optionally controlled living radical polymerization (LRP); living anionic polymerization; living cationic polymerization; and controlled polycondensation; iniferter-mediated polymerization, nitroxide-mediated polymerization (NMP), atom-transfer radical polymerization (ATRP) and reversible addition-fragmentation chain-transfer polymerization (RAFT), said polymerization being terminated when MIP particles of less than 1 micrometer have been formed; and
(d) separating said MIP particles from said template by washing and/or eluting thereby forming said solution or colloidal suspension, wherein said carrier substance and said immobilized template can be reused in additional controlled polymerizations of the type set forth in step (c) above.
US Pat. No. 10,189,935

WATER SOLUBLE CROSS-LINKED BLOCK COPOLYMERS

KEMIRA OYJ, Helsinki (FI...

1. A water soluble cross-linked block copolymer comprising block copolymers cross-linked together using a cross-linking agent, and whereini. each of the block copolymers contain a first block and a second block, and the first and the second block are formed from different monomer compositions,
ii. the first and second blocks are linked together with a molecular spacer derived from a bifunctional initiator used during the polymerization of said blocks, and
iii. the monomer compositions used in forming the first and second blocks contain one or more monomers selected from the group consisting of water-soluble non-ionic, cationic or anionic (meth)acrylic monomers, cationic non-acrylic monomers, itaconic acid, and N-vinylformamide, and derivatives thereof.
US Pat. No. 10,188,654

USES OF PYRIMIDO-PYRIDAZINONES TO TREAT CANCER

Asana BioSciences, LLC, ...

1. A method of treating a cancer subject, comprising administering to a cancer subject in need thereof, a therapeutically effective amount of a compound 2-(1-(4-((4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5-oxo-5,6-dihydropyrimido[4,5-d]pyridazin-2-yl)piperidin-4-yl)acetonitrile, or a pharmaceutically acceptable salt or ester thereof, wherein:the cancer subject has a recurrent or refractory cancer;
the cancer is a hematopoietic cancer; and
the cancer is refractory to Ibrutinib.
US Pat. No. 10,189,936

BLOCK COPOLYMER, DISPERSANT, AND PIGMENT DISPERSION COMPOSITION

OTSUKA CHEMICAL CO., LTD....

1. A block copolymer of an ABA type including an A block and a B block and having an acid value of 30 to 250 mgKOH/g, the B block containing a structural unit derived from a vinyl monomer with an acid group, wherein a structural unit derived from a vinyl monomer with an acid group and contained in the A block is at a content of 10% by mass or less in 100% by mass of the A block.
US Pat. No. 10,188,655

LIQUID PHARMACEUTICAL COMPOSITION COMPRISING PEMETREXED

Synthon B.V., Nijmegen (...

1. A liquid pharmaceutical composition suitable for parenteral administration comprising:a. 25-50 mg/ml of pemetrexed diacid;
b. arginine;
c. at least one monothiolic antioxidant;
d. 10-200 mg/ml of propylene glycol, and
e. one or more parenteral solvents,
wherein the preparation thereof is conducted in an atmosphere of inert gas and wherein the amount of arginine as a molar ratio to pemetrexed diacid is at least 2.5:1 (arginine:pemetrexed diacid) and said amount of arginine is sufficient to reach a pH of the composition in the range from 8.3 to 9.1.
US Pat. No. 10,189,937

FINE POWDER-COATED AMINE AND COMPOSITION CONTAINING SAME

SUNSTAR ENGINEERING INC.,...

1. A fine powder-coated amine comprising a solid amine having a melting point equal to or higher than 50° C. and a mean particle size equal to or smaller than 20 ?m, wherein the fine powder-coated amine has an amount of heat in the second absorption peak measured by a differential scanning calorimeter equal to or less than 220 J/g, and the surface of the solid amine is coated with fine particles having a mean particle size equal to or smaller than 2 ?m.
US Pat. No. 10,190,193

LEACHING OF MINERALS

GLENCORE TECHNOLOGY PTY L...

1. A method for treating a mineral composition containing iron, arsenic or other Group VA compounds comprising milling the mineral composition to a particle size of P80 of less than 25 ?m and leaching said mineral composition in the presence of lime and/or limestone and a soluble alkali complexing agent in the presence of an oxygen containing gas at a pH in the range of from 3.5 to 6.
US Pat. No. 10,190,194

COPPER ALLOY FOR ELECTRONIC AND ELECTRICAL EQUIPMENT, COPPER ALLOY THIN SHEET FOR ELECTRONIC AND ELECTRICAL EQUIPMENT, AND CONDUCTIVE COMPONENT FOR ELECTRONIC AND ELECTRICAL EQUIPMENT, TERMINAL

MITSUBISHI MATERIALS CORP...

1. A copper alloy for electronic and electrical equipment, comprising:more than 2.0 mass % to 36.5 mass % of Zn;
0.10 mass % to 0.90 mass % of Sn;
0.15 mass % to less than 1.00 mass % of Ni;
0.005 mass % to 0.100 mass % of P; and
a balance containing Cu and inevitable impurities,
wherein an atomic ratio Ni/P of an amount of Ni to an amount of P satisfies a relationship of 3.00 an atomic ratio Sn/Ni of an amount of Sn to an amount of Ni satisfies a relationship of 0.10 a strength ratio TSTD/TSLD is 1.10 or more, where strength TSTD is obtained when a tensile test is performed in a direction perpendicular to a rolling direction and strength TSLD is obtained when another tensile test is performed in a direction parallel to the rolling direction.
US Pat. No. 10,188,657

COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND THERAPY FOR MENIERE'S DISEASE

1. A method comprising administering to an individual diagnosed with Meniere's Disease a pharmaceutical composition comprising an effective amount of lamotrigine or a pharmaceutically acceptable salt thereof such that the effective amount of the lamotrigine or the pharmaceutically acceptable salt thereof is sufficient to reduce dizziness that is caused by the Meniere's Disease in the individual, and wherein the lamotrigine or the pharmaceutically acceptable salt thereof is the only bioactive compound in the pharmaceutical composition that is effective to treat the dizziness caused by the Meniere's Disease.
US Pat. No. 10,189,940

PROCESS FOR PROVIDING POLYMERS COMPRISING HEXAGONAL BORON NITRIDE

PepsiCo, Inc., Purchase,...

1. A method of preparing a polymer composition, the method comprisinga) providing a reactant mixture comprising a first monomeric or oligomeric reactant and exfoliated hexagonal boron nitride; and
b) polymerizing the first monomeric or oligomeric reactant in the reactant mixture to form the polymer composition that includes dispersed platelets of exfoliated hexagonal boron nitride;
wherein the polymer is selected from the group consisting of polyesters, polyamides, polyimides, polyurethanes, polycarbonates, and mixtures and copolymers thereof.
US Pat. No. 10,189,941

POLYCARBONATE COMPOSITIONS CONTAINING POLYETHYLENE WAX

Covestro Deutschland AG, ...

1. A polycarbonate composition comprisingA) polycarbonate
B) oxidized acid-modified polyethylene wax and
D) an inorganic filler,
wherein the oxidized acid-modified polyethylene wax has an acid number of <10 mg KOH/g determined according to JIS K0070, a crystallinity of greater than 60% and less than 90%, a melting point between 90° C. and 130° C. and a viscosity average molar mass determined by viscometry between 1500 g/mol and 5000 g/mol.
US Pat. No. 10,188,660

ANTI-HULRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE

AbbVie Inc., North Chica...

1. An anti-huLRRC15 antibody drug conjugate (ADC) comprising an antimitotic agent linked to an anti-huLRRC15 antibody by way of a linker, wherein the ADC has a structure of formula (I):[D-L-XY]n-Ab  (I)
or a salt thereof, wherein:
D is the antimitotic agent;
L is the linker;
Ab is the anti-huLRRC15 antibody;
XY represents a covalent linkage linking linker L to antibody Ab; and
n is an integer ranging from 2 to 8;
wherein
Ab comprises
a VH chain comprising the sequence of SEQ ID NO:16 and a VL chain comprising the sequence of SEQ ID NO:17,
a VH chain comprising the sequence of SEQ ID NO:26 and a VL chain comprising the sequence of SEQ ID NO:27,
a VH chain comprising the sequence of SEQ ID NO:36 and a VL chain comprising the sequence of SEQ ID NO:37,
a VH chain comprising the sequence of SEQ ID NO:46 and a VL chain comprising the sequence of SEQ ID NO:47,
a VH chain comprising the sequence of SEQ ID NO:56 and a VL chain comprising the sequence of SEQ ID NO:57,
a VH chain comprising the sequence of SEQ ID NO:66 and a VL chain comprising the sequence of SEQ ID NO:67, or
a VH chain comprising the sequence of SEQ ID NO:76 and a VL chain comprising the sequence of SEQ ID NO:77.
US Pat. No. 10,190,198

THICK FILM PASTE AND USE THEREOF

E I DU PONT DE NEMOURS AN...

1. A thick film paste composition comprising:(a) inorganic constituents that consist of:
a platinum source that is at least one of a particulate platinum (alloy) or a particulate platinum (alloy)/metal oxide composite, and
at least one metal compound selected from the group consisting of particulate metal oxides and precursor compounds capable of forming a metal oxide on firing, the metal oxide in each case being selected from the group consisting of NiO, SiO2, RuO2, Rh2O3, IrO2, Cu2O, CuO, TiO2, ZrO2, PbO, SnO2, CeO2, Al2O3, MgO, and MnO2; and
(b) an organic vehicle,
and wherein:
the proportion of the at least one metal compound is 0.001 to 1 wt. %, based on the total thick film paste composition; and
the thick film paste composition is capable of being fired to form an electrically conductive metallization that is electrically connected with an electrode on a ceramic sensor substrate.
US Pat. No. 10,188,661

TOPICAL DOSAGE REGIMEN

Topokine Therapeutics, In...

1. A method for locally reducing body fat in a subject in need thereof, the method comprising the steps of: administering a composition comprising latanoprost to the skin surface; and removing the composition or residue thereof from the skin surface between about 4 hours and about 12 hours, inclusive, after said administering;wherein more than about 60 percent of the 24-hour flux of latanoprost or an active metabolite thereof occurs within 4 to 12 hours, inclusive, after the step of administering, and wherein the step of removing is after more than about 60 percent of the 24-hour flux has occurred.
US Pat. No. 10,189,943

COPOLYMERS SUITABLE FOR MAKING MEMBRANES

BASF SE, Ludwigshafen (D...

1. A copolymer, comprising polyarylene ether blocks and hydrophilic-hydrophobic blocks,wherein:
said hydrophilic-hydrophobic blocks comprise polyisobutene blocks; and
said hydrophilic-hydrophobic blocks comprise polyisobutene blocks with terminal phenolic ether groups, and said phenolic ether groups are etherified with polyalkyleneoxides.
US Pat. No. 10,188,663

FULVESTRANT FORMULATIONS

Fresenius Kabi USA, LLC, ...

1. A composition comprising fulvestrant, a ricinoleate vehicle, and not more than 2% total impurities, wherein the composition is substantially free of a non-aqueous ester solvent following storage of the composition at room temperature for a period of 12 months.
US Pat. No. 10,189,945

METHOD FOR PRODUCING LIGHT-COLOURED TDI-POLYISOCYANATES

Covestro Deutschland AG, ...

1. A method for producing polyisocyanates comprising urethane groups and having APHA colour indices <50 Hazen comprising reacting di- to tetra-valent organic polyhydroxy compounds with excess amounts of toluylene diisocyanate and then removing unreacted excess toluylene diisocyanate to residual contents <0.5 wt. % by distillation, wherein the toluylene diisocyanate has a content of 2-chloro-6-isocyanato-methylcyclohexadienes <5 wt·ppm.
US Pat. No. 10,190,201

METHOD OF PRODUCING A COPPER-NICKEL-TIN ALLOY

MATERION CORPORATION, Ma...

1. A method of producing a spinodal copper-nickel-tin alloy, comprising:casting a copper-nickel-tin alloy;
homogenizing the alloy;
hot working the homogenized alloy to obtain a reduction ratio which is a minimum of about 5:1;
solution annealing the hot worked alloy at a temperature of from about 1470° F. to about 1650° F.;
cold working the solution annealed alloy until a reduction of area of from about 15% to about 80% occurs in the alloy; and
spinodally hardening the alloy after the cold working to produce a spinodal alloy;
wherein the copper-nickel-tin alloy consists of:
from about 5 wt % to about 20 wt % nickel;
from about 5 wt % to about 10 wt % tin;
minor additions, wherein the minor additions are selected from at least one of a group consisting of boron, zirconium, iron, niobium, manganese and magnesium, and wherein each of the minor additions is present at a content of no more than about 0.3% wt % in the spinodal alloy;
and
balance copper; and
wherein the alloy has a 0.2% offset yield strength of at least 110 ksi, an impact toughness of at least 12 foot-pounds when measured according to ASTM E23, V notch at room temperature, and an ultimate tensile strength of at least 120 ksi, and a minimum elongation of 20%.
US Pat. No. 10,188,664

INJECTABLE PHARMACEUTICAL COMPOSITIONS COMPRISING A CYCLODEXTRIN A HYDROPHOBIC DRUG, A CO-SOLVENT, AND A PRESERVATIVE

JUROX PTY LTD, South Wal...

1. An injectable pharmaceutical composition, in the form of a solution, wherein the injectable pharmaceutical composition complies with the European Pharmacopoeia 2011 Test for Efficacy of Antimicrobial Preservation, satisfying at least the A criteria for parenterals, comprising:1% w/v to 5% w/v alfaxalone,
8% w/v to 40% w/v 2-hydroxypropyl-?-cyclodextrin,
0.1% w/v to 0.15% w/v chlorocresol,
15% w/v ethanol, and
optionally a phosphate based buffer to provide a pH in a range of 6.0 to 7.5.
US Pat. No. 10,189,178

METHOD FOR PRODUCING WOOD MATERIAL PANELS, IN PARTICULAR OSB WOOD MATERIAL PANELS, AND WOOD MATERIAL PANEL THAT CAN BE PRODUCED IN ACCORDANCE WITH SAID METHOD

SWISS KRONO Tec AG, Luce...

1. A method of producing an OSB wood-base panel, comprising the steps of:a) providing wood strands;
b) applying at least one adhesive system to the wood strands, wherein the adhesive system comprises:
solely a polyurethane adhesive, and
nanoparticles below 500 nm, wherein at least one nanoparticle is modified with at least one compound of general formula (I)
RaSiX(4-a)  (I),
or of general formula (II)
ObXc(OH)dReSiO(4-b-c-d-e)/2  (II),
where
X is H, OH or a hydrolyzable moiety selected from the group consisting of: halogen, alkoxy, carboxyl, amino, monoalkylamino or dialkylamino, aryloxy, acyloxy, alkylcarbonyl,
R is a nonhydrolyzable organic moiety R selected from the group consisting of: substituted and unsubstituted alkyl, substituted and unsubstituted aryl, substituted and unsubstituted alkenyl, substituted and unsubstituted alkynyl, substituted and unsubstituted cycloalkyl, which may each be interrupted by —O— or —NH—, and
wherein R may include at least one functional group Q selected from a group containing an epoxy, hydroxyl, ether, amino, monoalkylamino, dialkylamino, substituted and unsubstituted anilino, amide, carboxyl, acryloyl, acryloyloxy, methacryloyl, methacryloyloxy, mercapto, cyano, alkoxy, isocyano, aldehyde, alkylcarbonyl, acid anhydride and/or phosphoric acid group,
a is =0, 1, 2, 3,
b, c, d are=0 or 1, and
e is =1, 2, 3;
wherein the adhesive system is admixed to the wood strands in an amount between 1.0 and 2.5 wt % based on the wood strands, and
c) pressing the wood strands admixed with the adhesive system to form the wood-base panel.
US Pat. No. 10,188,666

DENDROGENIN A AND ANTINEOPLASTIC AGENTS FOR THE TREATMENT OF CHEMOSENSITIVE OR CHEMORESISTANT TUMORS

AFFICHEM, Toulouse (FR) ...

1. A method for treating a cancer acute myeloid leukemia which is chemoresistant to an antineoplastic agent in a patient in need thereof comprising administering to said patient 5?-hydroxy-6?-[2-(1H-imidazol-4-yl)ethylamino]cholestan-3?-ol or a pharmaceutically acceptable salt thereof and said antineoplastic agent, wherein said antineoplastic agent is cytarabine.
US Pat. No. 10,190,204

METHOD FOR COATING LIGHT ALLOY RIMS

BASF SE, Ludwigshafen (D...

1. A method for coating light alloy rims, the method comprising:applying a primer (A) layer directly on a machined light alloy rim blank comprising a cast aluminum alloy, the primer (A) layer comprising at least one radiation-curable coating material having an acid number in accordance with DIN EN ISO 3682 (by potentiometry) of 10 to 120 mg KOH/g;
after applying the primer (A) layer, applying a base coat (B) layer;
after applying the base coat (B) layer, applying a radiation-curable clear coat (C) layer on an outside surface of the light alloy rim, the clear coat (C) layer having a double-bond density of free-radically polymerizable reactive groups per unit mass of coating material of at least 1 mol/kg; and
curing the primer (A) layer, the clear coat (C) layer, and optionally the base coat (B) layer by high-energy radiation selected from the group consisting of light in the wavelength range of 200 nm to 700 nm, an electron beam in the range of 150 keV to 300 keV, and combinations thereof;
wherein:
the primer (A) layer is fully cured with the high-energy radiation and without being further heated after being applied; and
the primer (A) layer, the base coat (B) layer, and the clear coat (C) layer are different from each other.
US Pat. No. 10,188,667

PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF 4-PREGENEN-11?-17-21-TRIOL-3,20-DIONE DERIVATIVES

ALLERGAN, INC., Irvine, ...

1. A method of treating an ocular condition associated with glucocorticoid and or mineralocorticoid receptor modulation which comprises topically administering to a patient in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of at least one compound selected from:(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13 -dimethyl-3 -oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl phenylacetate;
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl butyrate;
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13 -dimethyl-3 -oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate;
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl octanoate;
(8S,9S,10R,11S,13S,14S,17R)-17-Glycoloyl-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hexanoate;
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13 -dimethyl-3 -oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl benzoate;
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13 -dimethyl-3 -oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl heptanoate;
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl 2-methylpropanoate; and
(8S,9S,10R,11S,13S,14S,17R)-17-glycoloyl-11-hydroxy-10,13 -dimethyl-3 -oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl cyclopentanecarboxylate,
and further comprising carboxymethylcellulose, sodium phosphate, citrate buffer, and sodium chloride,
and having a pH from about 4.5 to 7.5.
US Pat. No. 10,188,668

CANCER DRUG AND USES

Health Clinics Limited, ...

1. A method of treating a cancer, the method comprising administering one or more cancer therapeutics to an individual with the cancer, wherein the one or more cancer therapeutics includea) a first cancer therapeutic that is a therapeutically effective dose of an anti-diabetic drug;
b) a second cancer therapeutic that is a therapeutically effective dose of a statin; and
c) a third cancer therapeutic that is a therapeutically effective dose of a glucose intake inhibitor.
US Pat. No. 10,188,669

MITOCHONDRIA-TARGETED ANTIOXIDANTS FOR TREATMENT OF AGE-RELATED BRAIN DISORDERS

MITOTECH S.A., Luxembour...

1. A method for providing to a mammal a neuroprotective effect against a brain pathology that is mediated by reactive oxygen species originating from mitochondria (mROS), wherein the brain pathology is selected from the group consisting of alcohol intoxication, hyperhomocysteinemia, and brain trauma, the method comprising the step of administering to the mammal an SkQ mitochondria-targeted antioxidant in an amount effective to provide said neuroprotective effect, wherein the SkQ mitochondria-targeted antioxidant is administered either prophylactically to inhibit the course of the pathology or for treatment of the pathology after its onset with the exception that, where the pathology is brain trauma, the SkQ mitochondria-targeted antioxidant is administered only for treatment after onset of the pathology.
US Pat. No. 10,188,702

METHODS AND COMPOSITIONS FOR TREATING HYPOGLYCEMIC DISORDERS

THE TRUSTEES OF THE UNIVE...

1. A method of treating congenital hyperinsulinism in a subject having congenital hyperinsulinism comprising administering to the subject an effective amount of a peptide wherein the amino acid sequence of the peptide consists of the amino acid sequence set forth in SEQ ID NO: 1.
US Pat. No. 10,188,704

ENHANCED MELANOMA CANCER PREVENTION BY NOVEL MELANOTROPINS

ARIZONA BOARD OF REGENTS ...

wherein Waa is a Met, Ile, or Leu, Xaa is a His or Pro, Yaa is an Arg or Leu, and Zaa is a Phe or Trp, and wherein R1 of the C-terminal is —NH2, or —OH, with the caveat that Waa is not Met, Xaa is not His, Yaa is not Arg, Zaa is not Trp, and R1 is not OH simultaneously.
US Pat. No. 10,189,766

PROCESS FOR PRODUCING 2-ETHYLHEXANAL HELPING TO IMPROVE YIELD

NAN YA PLASTICS CORPORATI...

1. A process for producing 2-ethylhexanal helping to increase yield of 2-ethylhexanal, comprises the following steps:1) placing a reaction liquid containing 60-100 wt % of 2-ethyl-2-hexenal into a single reaction tank having internally equipped with a gas-introducing mixer which comprising a hollow rotatory shaft thereof and vanes at a terminal of the hollow rotatory shaft for use in introducing and exhausting hydrogen gas to the reaction liquid and simultaneously stirring the reaction liquid if started;
2) based on the weight of 2-ethyl-2-hexenal, adding a palladium on carbon catalyst ranged from 0.02 wt % to 15 wt % for hydrogenation, whose palladium component is supported on a carbon carrier having a total content of impurities less than 8% by weight of the carbon carrier, and whose specific surface area of the impurities of the carbon carrier is ranged between 800 m2/g and 3,000 m2/g;
3) introducing hydrogen gas to 80-600 lb/in2 and holding this pressure;
4) activating the gas-introducing mixer to stir the reaction liquid at room temperature and held the pressure for 10 minutes, heating to 70-150° C., and allowing hydrogenation for 1-10 hours at this temperature; and
5) upon completion of the reaction, cooling the reaction liquid to room temperature and filtering out the catalyst to obtain a yield of the 2-ethylhexanal at least up to 98.0%.
US Pat. No. 10,189,818

5-(5-(2-(3-AMINOPROPDOXY)-6-METHOXYPHENYL)-1H-PYRAZOL-3-YLAMINO)PYRAZINE-2-CARBONITFILE (S)-LACTATE MONOHYDRATE

Eli Lilly and Company, I...

1. A compound which is 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile (S)-lactate monohydrate.
US Pat. No. 10,190,104

ISOFORM OF ANAPLASTIC LYMPHOMA KINASE AND ITS USES

Memorial Sloan Kettering ...

1. An isolated complementary DNA (cDNA) molecule comprising the nucleic acid sequence of exons 20-29 and a portion of intron 19 of an Anaplastic Lymphoma Kinase (ALK) gene, wherein the cDNA molecule does not comprise the nucleic acid sequence of exons 1-19 of the ALK gene, either individually or in any combination and wherein the portion of intron 19 of the ALK gene is about 400 bp in length located upstream of exon 20 of the ALK gene.
US Pat. No. 10,188,060

SOYBEAN CULTIVAR S170005

M.S. Technologies, LLC, ...

1. A plant of soybean cultivar S170005, representative seed of said soybean cultivar having been deposited under ATCC Accession No. PTA-124455.
US Pat. No. 10,188,082

METHODS FOR INCREASING GENETIC PROGRESS IN A LINE OR BREED OF SWINE USING SEX-SELECTED SPERM CELLS

Inguran, LLC, Navasota, ...

1. A method of producing an embryo or zygote in a genetic nucleus comprising the steps of:collecting a semen sample from a boar from the genetic nucleus;
sorting the semen sample into at least two subpopulations of sperm cells, wherein at least 60% of a first subpopulation bears X-chromosomes or Y-chromosomes;
fertilizing an egg from a sow from the genetic nucleus with one or more sperm cells from the first subpopulation to produce a zygote or embryo;
genotyping the zygote or embryo to obtain a genotype;
determining an estimated breeding value for the zygote or embryo; and
selecting the zygote or embryo to develop into offspring that is used for breeding in the genetic nucleus based on the estimated breeding value.
US Pat. No. 10,188,609

MICROPARTICLES COMPRISING A PROBIOTIC, CROSS-LINKABLE REAGENT, A DENATURED PROTEIN, POLYOL PLASTICISER AND TREHALOSE

ProGel Pty Ltd, Brisbane...

1. A microparticle precursor composition comprising a blend of a probiotic, a cross-linkable reagent, a denatured protein, a polyol plasticizer, trehalose and a carrier, wherein the blend does not contain a cross-linking reagent.