US Pat. No. 10,653,490

CHAIN FOR TRANSMITTING MOVEMENT BETWEEN ACTUATORS AND THE BASE OF A MEMBER FOR DRIVING A MOVABLE ELEMENT

ROBOCATH, Rouen (FR)

1. A movement transmission chain comprising:a drive member base for a mobile element;
three actuators piloting the base of the drive member respectively along three mutually distinct translation directions, by means of three respective interfaces with the base of the drive member;
wherein the intersection of the average surfaces of the three interfaces is located in the central region of the base of the drive member;
wherein the three interfaces are substantially flat;
these three interfaces are mutually orthogonal;
and these three interfaces are nested inside each other.

US Pat. No. 10,653,489

COUPLING INSTRUMENT DRIVE UNIT AND ROBOTIC SURGICAL INSTRUMENT

Covidien LP, Mansifled, ...

1. A surgical system for selective connection to a robotic arm, the surgical system comprising:an instrument drive unit including:
a first actuator;
a linkage member having a first portion and a second portion, the first and second portions opposing one another, the first portion operatively coupled to the first actuator such that actuation of the first actuator moves the first portion in a first direction and the second portion in a second direction opposite of the first direction; and
a drive member operatively coupled to the second portion of the linkage member; and
a surgical instrument detachably coupled to the instrument drive unit, the surgical instrument including:
a driven member operatively associated with the drive member of the instrument drive unit;
an end effector operatively coupled with the driven member, wherein translation of the driven member effects a first function of the end effector; and
a first cable having a first end coupled to the driven member and a second end operatively associated with the end effector.

US Pat. No. 10,653,488

SYSTEM AND METHOD FOR ROBOTIC SURGERY

MAKO Surgical Corp., For...

1. A method for optimizing removal of a targeted volume of tissue defined by a tissue removal envelope, said method comprising the steps of:tracking a position of an end effector portion of a cutting tool relative to the targeted volume of tissue using a tracking subsystem;
determining a tool path taken by the end effector portion relative to the targeted volume of tissue while a housing coupled to the cutting tool is manually grasped and manipulated by a user to remove a portion of the targeted volume of tissue with the end effector portion;
marking a subvolume of the tissue removal envelope to represent the portion of the targeted volume of tissue removed with the end effector portion; and
autonomously moving the end effector portion toward tissue that remains to be removed based on the marked subvolume of the tissue removal envelope so that the end effector portion avoids space in which tissue has already been removed thereby optimizing removal of the targeted volume of tissue.

US Pat. No. 10,653,487

LOAD CELLS IN AN INSTRUMENT DRIVE

CMR Surgical Limited, Ca...

1. A drive unit for providing drive from a robot arm to an instrument, the drive unit comprising:a load cell structure comprising a perimeter formed by a plurality of rings, wherein the plurality of rings are one-piece, monolithically formed with each other;
wherein each of the plurality of rings is connected to a respective flange by a respective deflectable web, wherein each respective flange defines a respective through-hole;
wherein each respective through-hole has a respective lead screw disposed therethrough.

US Pat. No. 10,653,486

REMOTE CONTROL APPARATUS FOR MEDICAL EQUIPMENT

MEDICAROID CORPORATION, ...

1. A remote control apparatus for a surgery assisting system including a manipulator that supports surgical equipment, comprising:a display configured to display an image captured by an endoscope and including a drip section that is provided on a lateral side of the display and that is to be gripped by an operator when moving the display;
a display supporting arm that includes a plurality of links, a plurality of joints each of which connects adjacent two of the plurality of links, and a plurality of locking mechanisms provided to the plurality of joints respectively and configured to lock the plurality of joints respectively, wherein the display supporting arm supports the display;
an operation handle that allows the operator to operate the manipulator; and
an unlocking trigger configured, in response to an operation by the operator, to unlock the plurality of locked joints of the display supporting arm simultaneously, wherein
the unlocking trigger is provided on the grip section of the display and unlocks the plurality of joints locked by the plurality of locking mechanisms only while being operated by the operator.

US Pat. No. 10,653,485

SYSTEM AND METHOD OF INTRALUMINAL NAVIGATION USING A 3D MODEL

COVIDIEN LP, Mansfield, ...

1. A system for lung navigation comprising:a tracking system receiving signals from a probe;
a workstation in operable communication with the tracking system; and
a user interface in operable communication with the workstation, wherein the user interface is configured to display:
a three-dimensional (3D) lung model generated from a plurality of computer tomography (CT) images;
a planned pathway to a target on the 3D lung model;
an image of at least a portion of a digital probe in the 3D lung model, wherein a displayed position of the image of the at least a portion of the digital probe in the 3D model corresponds to signals from the probe; and
the 3D model with an object that is hidden or ghosted out.

US Pat. No. 10,653,484

DEVICES AND METHODS FOR ANATOMIC MAPPING FOR PROSTHETIC IMPLANTS

Aortica Corporation, Bel...

1. A method, comprising:receiving a digital representation of a patient's aorta, the digital representation including data representative of an original branch blood vessel location;
receiving a user input;
determining a predicted branch blood vessel location based on an expected change in position of the patient's aorta; and
generating a model of the patient's aorta, the model including data representative of the predicted branch blood vessel location.

US Pat. No. 10,653,483

RECONFIGURABLE HANDHELD LASER TREATMENT SYSTEMS AND METHODS

LUMENIS LTD, (IL)

1. A handheld laser treatment apparatus, wherein the apparatus comprises:a handset including a treatment chamber, the treatment chamber having an open treatment aperture and a closed bottom of the treatment chamber; a laser array in the closed bottom arranged to project laser energy out from the treatment chamber to outside the treatment chamber through the open treatment aperture; and a pre-cooled circulating liquid coolant circuit within the handset; and,
an attachment, the attachment comprising a distal end and a proximal end;
the attachment being arranged for insertion into the open treatment aperture, the attachment including an optical element mounted at the distal end of the attachment;
the attachment being open from the proximal end to the distal end so that the optical element in the attachment proximal end receives laser energy projected by the laser array in the treatment chamber and transmits light to the distal end when inserted in the chamber, the optical element thereby accumulating thermal energy from projected laser energy;
the attachment further comprising a closed liquid circulating system comprising one or more liquid delivery channels within the attachment and around the optical element and a heat exchange interface coupled to the one or more liquid delivery channels;
the heat exchange interface being couplable to the pre-cooled circulating liquid coolant circuit in the handset;
wherein, when coupled, heat generated in the liquid within the closed liquid circulating system within the attachment due to accumulating thermal energy is absorbed by the pre-cooled circulating liquid coolant circuit through the heat exchange interface.

US Pat. No. 10,653,482

SYSTEM FOR VAPORIZATION OF TISSUE

Boston Scientific Scimed,...

1. An apparatus, comprising:a solid-state laser capable of producing laser radiation, wherein the laser comprises a laser element assembly, a pump source, a Lithium Triborate frequency doubling crystal, and a controller, wherein:
the laser element assembly is configured to output 1064 nm light toward the Lithium Triborate frequency doubling crystal to produce second harmonic 532 nm light; and
the controller is configured to cause the laser to generate, in a macro-pulse mode, a plurality of macro-pulses, each macro-pulse comprising a train of 2 to 12,200 micro-pulses, each micro-pulse being less than one microsecond in duration separated by 40 microseconds from adjacent micro-pulses;
an optical fiber coupled to the laser and adapted to deliver laser radiation,
one or more first mirrors configured to direct light from the laser element assembly toward the Lithium Triborate frequency doubling crystal, wherein the one or more first mirrors reflect both 1064 nm and 532 nm light;
a second mirror that reflects 1064 nm light and is transparent to 532 nm light, wherein the second mirror forms an output window through which the 532 nm light passes through; and
a user interface comprising a touch screen and a control knob, the user interface being configured to:
display an average power setting on the screen;
display a parameter box on the screen; and
adjust a parameter of the laser when a user touches the parameter box on the screen and then turns the knob.

US Pat. No. 10,653,481

IRRIGATED ABLATION ELECTRODE ASSEMBLY HAVING OFF-CENTER IRRIGATION PASSAGEWAY

St. Jude Medical, Atrial ...

1. A distal assembly of an irrigated ablation catheter, comprising:a manifold and an ablation electrode extending along a central axis;
a temperature sensor disposed in the electrode configured to produce a temperature signal indicative of a temperature value of the electrode;
the manifold comprising a distribution cavity, wherein the manifold is configured for connection to a distal end of a shaft of the catheter, wherein a longitudinal axis of a first portion of the distribution cavity is offset in distance from the central axis by a first amount of offset, and wherein a longitudinal axis of a second portion of the distribution cavity extends along the central axis of the manifold;
the ablation electrode including a first irrigation passageway.

US Pat. No. 10,653,480

METHOD FOR CONSTRUCTING IRRIGATED BALLOON CATHETER WITH FLEXIBLE CIRCUIT ELECTRODE ASSEMBLY

BIOSENSE WEBSTER (ISRAEL)...

1. A method of constructing a flexible circuit electrode assembly for use in assembling an electrophysiology balloon catheter adapted for use in an ostium, the method comprising:providing a flex circuit having a substrate, a first conductive layer and a second conductive layer;
removing the first conductive layer to expose a first surface of the substrate;
forming a wiring electrode in the second conductive layer with one exclusion zone;
forming a first through-hole in the substrate to provide one conductive via and forming a second through-hole to provide an irrigation aperture in alignment with the exclusion zone;
forming a contact electrode on the first surface of the substrate,
wherein at least one of the forming the wiring electrode and the forming the contact electrode includes introducing conductive material into the first through-hole to form the conductive via, the conductive via extending through the substrate and electrically coupling the wiring electrode and the contact electrode.

US Pat. No. 10,653,479

ENHANCED ABLATION AND MAPPING CATHETER AND METHOD FOR TREATING ATRIAL FIBRILLATION

BIOSENSE WEBSTER, INC., ...

1. A catheter for ablating tissue, the catheter comprising:an elongated generally-tubular catheter body having proximal and distal ends and a longitudinal axis;
a non-conductive tubing mounted on the distal end of the catheter body; and
an electrode assembly mounted on the non-conductive tubing, the electrode assembly including a porous electrode arrangement that is generally transverse to the catheter body, the porous electrode arrangement comprising:
a single, continuous coiled electrode wrapped around at least a portion of the non-conductive tubing, the single, continuous coiled electrode being electrically connectable to a suitable energy source;
a porous sleeve mounted in surrounding relation to the coiled electrode and defining an open space between the porous sleeve and the coiled electrode; and
one or more irrigation openings in the non-conductive tubing between turns of the coiled electrode fluidly connecting the open space to a lumen extending through the catheter through which fluid can pass, the one or more irrigation openings being only on a side of the coiled electrode facing away from the catheter body;
wherein, in use, fluid passes through the lumen in the catheter, through the one or more irrigation openings, into the open space and through the porous sleeve.

US Pat. No. 10,653,478

DEBRIDEMENT DEVICE AND METHOD

Medtronic Advanced Energy...

1. A method of surgically cutting and sealing tissue comprising:positioning a distal end region of a debridement device at an operative site within a patient, the debridement device having an outer shaft comprising a lumen and a distal end comprising a cutter forming a cutting window, the device further comprising an inner shaft rotatably disposed within the lumen of the outer shaft, the inner shaft having a distal portion comprising a cutter forming a cutting window, the outer shaft and the inner shaft forming a fluid passage therebetween, the device further comprising a bipolar electrode assembly including first and second electrodes that are electrically isolated from one another and positioned at the distal end region, the bipolar electrode assembly further including first and second electrical contacts coupled to the first and second electrodes, respectively, the device further comprising a proximal region opposite the distal end region and including housing maintaining a button, the button being manually transitionable to an activation position;
grasping the housing by a hand of a user;
cutting tissue at the operative site with the inner shaft cutter and the outer shaft cutter by moving the inner shaft relative to the outer shaft;
transitioning the button to the activation position, including simultaneously completing an electrical pathway between each of the first and second electrical contacts and an energy source;
delivering bipolar RF energy to the first and second electrodes in response to the button being held in the activation position to apply RF energy to tissue of the operative site; and
terminating the delivery of bipolar RF energy to the first and second electrodes upon releasing the button from the activation position.

US Pat. No. 10,653,477

ELECTROSURGICAL DEVICE

GYRUS MEDICAL LIMITED, C...

1. A surgical instrument comprising:a handle,
an elongate shaft that defines a central axis with a forward direction and a rearward direction, and extends from the handle to a distal end in the forward direction,
an end effector positioned at the distal end of the elongate shaft,
a blade assembly that is disposed within the elongate shaft, and extends from a proximal end to a distal end, the blade assembly including a cutting blade located at the distal end, the cutting blade being located in proximity to the end effector, the blade assembly being connected at the proximal end to a component within the handle, and
a trigger mechanism located on the handle and movable between a first position and a second position, movement of the trigger mechanism from the first position to the second position causing a longitudinal movement of the blade assembly so as to cause a longitudinal advancement of the cutting blade with respect to the end effector, the trigger mechanism comprising:
a trigger arm including a proximal end and a distal end, and being pivotable about a first pivot axis located between the proximal and distal ends,
a frame comprising a proximal end and a distal end, the proximal end of the frame being connected to the distal end of the trigger arm by means of a second pivot axis, the first pivot axis and the second pivot axis being offset from the central axis of the shaft on opposite sides thereof,
a collar directly connected to the distal end of the frame by means of a third pivot axis, the third pivot axis being positioned on the central axis of the shaft, and being forward of the second pivot axis in the forward direction, the arrangement being such that the movement of the trigger mechanism from the first position to the second position is constituted by pivoting the trigger arm about the first pivot axis, causing the frame to move the collar with respect to the trigger arm, the collar being further connected to the component such that movement of the collar causes the longitudinal movement of the blade assembly, and
a spring attached at one end to the trigger arm and at the other end to the collar so as to bias the trigger mechanism into the first position.

US Pat. No. 10,653,476

MAPPING VESSELS FOR RESECTING BODY TISSUE

Covidien LP, Mansfield, ...

1. A method of resecting tissue, comprising:locating a vessel;
clamping the vessel with an end effector assembly having first and second jaw members to create a boundary for the delivery of a contrast agent to predetermined portions of tissue;
injecting the contrast agent into an interior space of the vessel through a tip of at least one needle of the end effector assembly, wherein a fluid conduit in communication with the at least one needle is defined within at least one of the first or second jaw members of the end effector assembly;
creating images of the tissue based upon the location of the contrast agent within the tissue;
identifying a cut line based on the images created with the contrast agent; and
cutting the tissue along the cut line to resect predetermined portions of the tissue.

US Pat. No. 10,653,475

KNIFE LOCKOUT FOR ELECTROSURGICAL FORCEPS

COVIDIEN LP, Mansfield, ...

1. An electrosurgical forceps, comprising:first and second shafts each having a jaw member disposed at a distal end thereof, the shafts configured to rotate about a pivot to move the jaw members between an open position and a closed position;
a knife deployment mechanism disposed on one of the first or second shafts;
a knife operably coupled to the knife deployment mechanism via a pivot pin, the knife deployment mechanism configured to move the knife between a retracted position and an extended position;
a switch assembly disposed on one of the first or second shafts and configured to be engaged by the other of the first or second shafts when the jaw members are in the closed position to move the switch assembly between a deactivated position and an activated position to control delivery of electrosurgical energy to the jaw members; and
a knife lockout defining a first stop and a second stop spaced from the first stop, the knife lockout configured to move between a first position, a second position, and a third position, wherein:
when the knife lockout is in the first position, the jaw members are in the open position and the pivot pin contacts the first stop to prevent distal movement of the pivot pin and movement of the knife from the retracted position to the extended position;
when the knife lockout is moved from the first position to the second position, the jaw members are in the closed position, the switch assembly is in the deactivated position, and the pivot pin no longer contacts the first stop such that movement of the knife from the retracted position to the extended position is permitted; and
when the knife lockout is moved from the second position to the third position, the jaw members are in the closed position, the switch assembly is in the activated position, and the pivot pin is received within a recess defined by the second stop to prevent distal movement of the pivot pin and movement of the knife from the retracted position to the extended position.

US Pat. No. 10,653,474

SURGICAL VAPORIZATION ELECTRODE

1. A surgical vaporization electrode, comprising:an electrical connecting line;
an electrically conductive electrode head having:
a rear area facing the electrical connecting line;
a working surface electrically connected to the electrical connecting line and facing away from the electrical connecting line and being either planar or convexly outwardly curved;
an electrode region, which is set back with respect to the working surface, such that the setback electrode region is bordered, on at least two sides thereof, by a section of the working surface; and
a curved boundary region, where the working surface edgelessly merges into the rear area,
wherein a minimum local radius of curvature of the boundary region is not smaller than one-thirtieth of a dimension of the electrode head in a direction of a maximum extent of the electrode head; and
an electrically conductive electrode element, which is arranged in the setback electrode region and is electrically connected to the electrical connecting line and which has a free end,
wherein the electrically conductive electrode element has, in at least one location thereof, a local radius of curvature that is smaller than the minimum local radius of curvature of the boundary region.

US Pat. No. 10,653,473

OPERATING ROOM MULTIFUNCTION CABLE SYSTEM

1. A multifunction cable for use in an operating room comprising:an elongate body of sufficient length to stretch from a first end in a non-sterile equipment region to a second end disposed in a sterile region of the operating room;
a plurality of channels comprising electrical conductors and fluidic tubes contained within the elongate body;
a plurality of first end connectors at the first end of the elongate body for connecting the channels to at least two mechanisms disposed in the non-sterile equipment region; and
a terminus located at the second end of the elongate body and disposed in the sterile region of the operating room, the terminus comprising:
terminus connectors for removably attaching at least two tools or instruments to the terminus;
flexible electrical leads and flexible fluidic tubing connecting the terminus connectors to appropriate channels within said cable; and
surgeon operated retraction mechanisms for releasing and retracting the flexible electrical leads and flexible fluidic tubing on demand.

US Pat. No. 10,653,472

TOUCH FREE OPERATION OF ABLATOR WORKSTATION BY USE OF DEPTH SENSORS

Biosense Webster (Israel)...

1. A system for touch-free operation of an ablator workstation by an associated user, comprising:a depth sensor configured to detect location of the associated user and gesture of a body part of the associated user; and
a processor with a memory device, wherein the memory device is configured to store instructions that, when executed by the processor, cause the processor to:
predict a subsequent location of the user based on an initial location of the user,
detect the subsequent location of the user to determine if the subsequent location of the user is within the predicted location of the user,
detect a gesture of the body part, wherein initiation of the gesture occurs after prediction of the subsequent location of the user,
validate the gesture based on a physical characteristic of the gesture, and
identify the gesture as being unauthorized when the subsequent location of the user is beyond the predicted location of the user.

US Pat. No. 10,653,471

SYSTEMS AND METHODS FOR ARC DETECTION AND DRAG ADJUSTMENT

COVIDIEN LP, Mansfield, ...

1. An electrosurgical generator for providing electrosurgical energy to an electrode of an electrosurgical instrument, the electrosurgical generator comprising:an output stage configured to provide electrosurgical energy to the electrode of the electrosurgical instrument;
a sensor configured to sense at least one of a voltage waveform or a current waveform of the electrosurgical energy delivered to the electrode; and
a controller coupled to the output stage and the sensor, the controller configured to detect harmonic distortion of the at least one of the voltage waveform or the current waveform, determine a drag force on the electrode based on the harmonic distortion, and control a level of the electrosurgical energy delivered to the electrode based on the drag force.

US Pat. No. 10,653,470

COMPRESSIBLE MIXING AND DELIVERY SYSTEM FOR MEDICAL SUBSTANCES

Spinal Generation, LLC, ...

1. A method of mixing and delivering a substance to a bone, comprising:providing a compressible tube having a reservoir and an exit portal, the compressible tube containing at least a first substance element therein;
introducing a second substance element to the first substance element;
introducing a mixing apparatus into the reservoir through the exit portal;
mixing the first substance element and the second substance element using the mixing apparatus to form the substance within the reservoir of the compressible tube;
removing the entirety of the mixing apparatus from the reservoir; and
delivering the substance through the exit portal in the compressible tube for delivery to the bone using a compressing device.

US Pat. No. 10,653,469

ORTHOPEDIC IMPLANT INSTALLATION USING MAGNETICALLY DRIVEN SCREWS

BIOSENSE WEBSTER (ISRAEL)...

1. An orthopedic implant for insertion into a bone, the implant comprising:an implant body; and
one or more self-tapping screws, wherein each screw comprises one or more magnets that are mechanically coupled to the screw and configured to induce perimetrically alternating magnet poles such that the one or more self-tapping screws are magnetically activated, the one or more self-tapping screws being prepositioned in the implant body transversally to a longitudinal axis of the implant body, wherein the one or more self-tapping screws are configured to rotate under an influence of an externally applied magnetic field so as to protrude into a bone and lock the orthopedic implant in place.

US Pat. No. 10,653,468

FOUR CORNER FUSION DEVICE

1. A method for fusing bones comprising:surgically accessing the bones to be fused;
removing cartilage from between the bones to be fused;
cutting a concave channel in at least a subset of the bones to be fused using a burr;
placing an elongated plate into the channel, the elongated plate having a top face and a bottom face, defining a plurality of screw apertures therethrough, having a longitudinal dimension between a first end and a second end, and having a lateral dimension between a first side and a second side, with the plurality of screw apertures arranged in a generally straight line along the longitudinal dimension of the elongated plate, and with three or more of the screw apertures configured to facilitate different trajectories of bone screws through each of the three or more apertures;
drilling a Kirschner wire through each of the plurality of screw apertures and into at least one of the bones to be fused using a drill guide inserted into the plurality of screw apertures, with the drill guide configured to limit angulation of the Kirschner wire relative to the elongated plate;
drilling pilot holes in the bones to be fused using a cannulated drill bit and using the Kirschner wires to guide angulation of the pilot hole as it is drilled in the bone;
inserting cannulated screws over the Kirschner wires, through the screw apertures, and into the drilled holes;
tightening the cannulated screws to fixedly stabilize the bones to be fused.

US Pat. No. 10,653,467

INTRA-OSSEOUS PLATE SYSTEM AND METHOD

Treace Medical Concepts, ...

1. A method of plating a bone, comprising the steps of:forming an opening in a longitudinal side of a cuneiform and in a longitudinal side of a metatarsal;
placing an intra-osseous support structure in the opening and across a tarsal-metatarsal joint;
inserting a first fastener through the cuneiform and into the intra-osseous support structure; and
inserting a second fastener through the metatarsal and into the intra-osseous support structure.

US Pat. No. 10,653,466

BONE PLATE

DePuy Synthes Products, I...

1. A bone plate, comprising:a body having a first surface which, in an operative configuration, faces away from a bone on which the plate is to be mounted and a second surface, which in the operative configuration, faces the bone, the body including a first section extending along a first longitudinal axis and a second section extending along a second longitudinal axis angled with respect to the first longitudinal axis;
a first hole extending through the body from the first surface to the second surface and defining a first hole axis, the first hole being structured to lockingly engage a head of a first bone anchor inserted therein such that a shaft of the first bone anchor extends along the first hole axis; and
a second hole extending through the body and spaced apart from the first hole, the second hole defining a second hole axis and being structured to lockingly engage a head of a second bone anchor inserted therein such that a shaft of the second bone anchor extends along the second hole axis, the first and second hole axes defining a single plane and intersecting at a point on a side of the bone plate facing the second surface,
wherein the second section is connected to the first section such that the second section lies in a plane different from that of the first section.

US Pat. No. 10,653,465

METATARSAL FIXATION DEVICE, SYSTEM AND METHOD

WRIGHT MEDICAL TECHNOLOGY...

1. A plate for fixing an osteotomy or fracture of a bone comprising:an elongate portion defining a proximate end and a distal end, the elongate portion configured to extend along a shaft of the bone having the osteotomy or fracture;
a clamp disposed at the distal end of the elongate portion, the clamp having:
a first resilient arm extending outwardly and downwardly from a lateral side of the distal end of the elongate portion;
a second resilient arm extending outwardly and downwardly from a medial side of the distal end of the elongate portion;
at least one first attachment structure extending outwardly from an inner surface of the first resilient arm; and
at least one second attachment structure extending outwardly from an inner surface of the second resilient arm; and
an angled section adjacent to the clamp such that the clamp is offset from the elongate portion toward a lateral side of the elongate portion;
wherein the first and second resilient arms are normally biased to compress against lateral and medial sides of a head of the bone having the osteotomy or fracture and any associated soft tissue.

US Pat. No. 10,653,464

FOOT BONE PLATE PROVIDING FIXATION AND COMPRESSION

LIFE SPINE, INC., Huntle...

1. An implant for fixing and compressing two adjacent bone portions across their juncture, the implant comprising:an elongate body defining a longitudinal axis and having an upper surface, a lower surface opposite the upper surface; a first lateral side, a second lateral side opposite the first lateral side, a first end, and a second end opposite the first end;
a plurality of cylindrical bores in the elongate body, at least one of the cylindrical bores having a first axis that extends between the upper surface of the elongate body and the lower surface of the elongate body, the plurality of cylindrical bores situated along the elongate body from the first end to the second end thereof, each cylindrical bore configured to receive and hold a bone screw in one of the two adjacent bone portions; and
a flange having a first portion and a second portion, the first portion extending from the first lateral side of the elongate body, the first portion comprising a neck having a recessed surface between the upper surface of the elongate body and the second portion of the flange, the second portion of the flange extending generally perpendicular to the lower surface of the elongate body and having a first surface, a second surface opposite the first surface, and a cylindrical bore with a second axis that extends between the first and second surfaces of the second portion;
wherein the first axis is generally perpendicular to the first longitudinal axis;
wherein the second axis extends at an oblique angle relative to the longitudinal axis of the elongate body so that a bone screw received in the cylindrical bore of the flange extends into the two adjacent bone portions and across their juncture;
wherein the longitudinal axis, the first axis, and the second axis are offset to each other and do not intersect; and
wherein bone screws used in the plurality of cylindrical bores of the elongate body provide fixation of the elongate body to the two adjacent bone portions, wherein a bone screw used in the cylindrical bore of the flange provides compression of the two adjacent bone portions across their juncture.

US Pat. No. 10,653,463

CONTROLLING THE DEGRADATION OF BIORESORBABLE METAL IMPLANTS

DePuy Synthes Products, I...

1. A method of controlling the degradation of a tissue implant comprising:securing an implant to tissue, wherein the implant has a body consisting essentially of a first material, and the body has at least one aperture;
positioning an insert within the at least one aperture to substantially fill the at least one aperture, the insert consisting essentially of a second material that is of a lower nobility than the first material.

US Pat. No. 10,653,462

CORTICAL BONE PIN

LifeNet Health, Virginia...

1. A pin for fusing bones of a human patient, having an elongated body, comprising: a proximal portion; a distal portion; barbs on the proximal portion; and barbs on the distal portion, wherein the barbs on the proximal portion have a profile such that, as the barbs proceed from a distal end to a proximal end, the barbs slope abruptly from a trough to a crest and slope gradually from a crest to a trough, and the barbs on the distal portion have a profile such that, as the barbs proceed from a distal end to a proximal end, the barbs slope gradually from a trough to a crest and slope abruptly from a crest to a trough, the pin further comprising a shoulder extending outwardly from the pin between the proximal portion and the distal portion, wherein the shoulder has an apex and sloped surfaces facing proximally and distally from the apex of the shoulder, wherein the pin comprises cortical bone, and wherein the pin has a substantially circular cross section along its entire length.

US Pat. No. 10,653,461

ROD REDUCER

K2M, Inc., Leesburg, VA ...

1. A rod reducer comprising:a housing defining an opening;
a body member defining a slot and cavities;
a shaft received through the opening of the housing and rotatably coupled with the body member;
first and second arm members coupled to the housing, the first and second arm members extending through the respective cavities of the body member, the first and second arm members transitionable between an approximated position and a spaced apart position;
a biasing member slidably coupled with the body member; and
an anvil coupled with the biasing member such that the anvil is biased distally, wherein rotation of the shaft causes axial displacement of the anvil, the axial displacement of the anvil directly transitioning the first and second arm members between the approximated and spaced apart positions.

US Pat. No. 10,653,460

ORTHOPEDIC IMPLANT ROD REDUCTION TOOL SET AND METHOD

1. A bone anchor comprising:a receiver and a closure, the receiver attachable with a lower portion of a tool at an inner surface of the tool, the inner surface continuous with a tool channel, the receiver comprising:
a pair of laterally spaced upstanding arms extending about a longitudinal axis of the receiver, the pair of laterally spaced upstanding arms forming a rod-receiving channel therebetween, the rod-receiving channel being closed by the closure, the tool channel being alignable with the receiver channel, each of the laterally spaced upstanding arms comprising:
an external surface extending from a front side to a back side of the receiver;
an upper surface; and
a single non-threaded tool engaging laterally opening groove formed on the external surface and extending from at least one of the front side and the back side of the receiver, the laterally opening groove spaced from the upper surface and slanted relative to the longitudinal axis of the receiver,
wherein the closure is positionable within the channel when the tool is attached to the laterally opening groove, the tool is attached to the laterally opening groove by twisting the tool to engage the laterally opening groove, and the laterally opening groove is adapted to distally drive the tool during the twisting.

US Pat. No. 10,653,459

SPINAL FIXATION AIMING APPARATUS

1. A spinal fixation aiming apparatus, comprising:a spinal fixation aiming device, which comprises an arc guide rail, an arc slide unit that is movably coupled to the arc guide rail, and a tool holder that is mounted to the arc slide unit, two ends of the arc guide rail being each formed with a mounting hole, the tool holder being movable to and selectively fixed at a predetermined location, wherein the arc guide rail, the arc slide unit, and the tool holder are each formed of a light-transmitting material;
a first adjustment unit, which is coupled to one of the mounting holes of the arc guide rail for adjusting inclination and height of the spinal fixation aiming device;
a second adjustment unit, which is coupled to the first adjustment unit for adjustably setting the spinal fixation aiming device to a first horizontal position or a second horizontal position; and
an extendible/retractable bar, which is movably coupled to the second adjustment unit for adjusting a height of the spinal fixation aiming device;
wherein the arc guide rail and the arc slide unit together form a spherical surface that define two separate arcs of the spherical surface such that the arc slide unit and the tool holder are able to slide along a spherical arc surface of the arc slide unit.

US Pat. No. 10,653,458

METHODS FOR IMPLANTING A BONE SCREW

Providence Medical Techno...

1. A method for implanting a bone screw in a vertebra, the method comprising:delivering the bone screw and a bone screw delivery mechanism near the vertebra, wherein a first end of the bone screw is attached to a second end of the bone screw delivery mechanism at a breakable junction;
advancing the bone screw and the bone screw delivery mechanism to contact the vertebra, wherein the bone screw is advanced at a first angle relative to a longitudinal axis extending through a facet joint implant located in a facet joint formed by the vertebra and an adjacent vertebra;
rotating the bone screw delivery mechanism to cause the bone screw to screw into the vertebra;
detaching the bone screw delivery mechanism from the bone screw by breaking at the breakable junction;
delivering a second bone screw and a second bone screw delivery mechanism near the adjacent vertebra, wherein an end of the second bone screw is attached to an end of the second bone screw delivery mechanism at a breakable junction;
advancing the second bone screw and bone screw delivery mechanism to contact the adjacent vertebra, wherein the second bone screw is advanced at a second angle relative to a longitudinal axis extending through the facet joint implant located in the facet joint formed by the vertebra and the adjacent vertebra;
rotating the second bone screw delivery mechanism to cause the second bone screw to screw into the adjacent vertebra; and
detaching the second bone screw delivery mechanism from the second bone screw by breaking at the breakable junction.

US Pat. No. 10,653,457

MULTI-FUNCTION DRIVER INSTRUMENTS AND RELATED METHODS

Medos International Sarl,...

1. A driver instrument, comprising:an inner driver shaft having an inner drive tip; and
an outer driver shaft in which the inner driver shaft is at least partially disposed, the outer driver shaft having an outer drive tip, the outer drive tip comprising a plurality of distally extending teeth;
wherein the instrument has:
a first configuration in which the inner drive tip is retracted proximally from the outer drive tip and an input torque applied to the inner driver shaft is transferred to the outer driver shaft and the outer drive tip; and
a second configuration in which the inner drive tip is advanced distally from the outer drive tip and an input torque applied to the inner driver shaft is not transferred to the outer driver shaft or the outer drive tip,
wherein, in the first configuration, the plurality of distally extending teeth of the outer drive trip are configured to extend into an outer set screw of a fastener and apply torque to the outer set screw independently from an inner set screw of the fastener, and
wherein, in the second configuration, the inner drive tip is configured to apply torque to the inner set screw of the fastener independently from the outer set screw.

US Pat. No. 10,653,456

INTERSPINOUS SPACER

VERTIFLEX, INC., San Cle...

1. An implant for placement between adjacent spinous processes in a spinal motion segment, the implant comprising:a body defining a longitudinal axis;
a first arm rotatably connected to the body and including a pair of first extensions configured to receive a first spinous process between the first extensions to laterally stabilize the body with respect to the first spinous process when in a deployed configuration;
and a second arm rotatably connected to the body and including a pair of second extensions configured to receive a second spinous process between the second extensions to laterally stabilize the body with respect to the second spinous process when in a deployed configuration; and
wherein the first and second arms in a undeployed configuration are positioned for placement between adjacent spinous processes in which at least one of the adjacent spinous processes has a projection in a coronal plane that is angled with respect to a sagittal plane of the implant, wherein the implant operates to drive each of the first and second arms along a respective are of at least 90 degrees to rotate from the undeployed configuration to a deployed configuration such that the first and second extensions move away from the longitudinal axis and each other,
wherein the first arm is pivotally coupled to the body such that the first extensions rotate together relative to the body to allow positioning of both of the first extensions on either side of the sagittal plane of the implant and positioning of the first spinous process between the first extensions when in the deployed configuration.

US Pat. No. 10,653,455

SPINAL IMPLANT SYSTEM AND METHODS OF USE

Warsaw Orthopedic, Inc., ...

1. A bone fastener comprising:a first member defining an implant cavity and a bore extending through a distal end of the first member;
a second member comprising a proximal portion and a distal portion configured to penetrate tissue, the proximal portion including a threaded inner surface defining an opening, the proximal portion defining a transverse slot; and
a third member comprising a head configured for disposal within the bore and threaded shaft configured for engagement with the threaded inner surface to selectively translate the implant cavity relative to the second member, the head having a maximum diameter less than a maximum diameter of the bore.

US Pat. No. 10,653,454

SPINAL FIXATION SYSTEMS

1. A spinal stabilization system securable with a plurality of vertebrae, the system comprising:at least one anchor configured for attachment to at least two vertebrae;
a plurality of spanning structures extending between and securable with the at least one anchor, each spanning structure having an adjustable bending stiffness;
wherein the plurality of spanning structures are arranged in layers extending substantially the distance between the at least two vertebrae;
wherein each of the spanning structures is adjusted to impart a different bending stiffness between its respective anchors;
wherein the bending stiffness of each of the spanning structures is adjustable after being secured with the anchors;
wherein the layers comprise an outer member of a first cross-sectional area and an inner portion of a second cross-sectional area that is larger than the first cross-sectional area; and
wherein the outer member cross-sectional area is smaller than the inner portion cross-sectional area, the outer member and inner portion being configured to be positioned substantially within another structural member, the combined members being retained with a first end securable with a first vertebral body and a second end operatively fixable with a second vertebral body.

US Pat. No. 10,653,453

DYNAMIC STABILIZATION SYSTEMS AND ASSOCIATED METHODS

Zimmer Biomet Spine, Inc....

1. A system, comprising:a delivery device comprising a distal end, a proximal end, and a lumen extending from the distal end to the proximal end;
an annular anchor removably coupleable to the distal end of the delivery device, the anchor implantable at a target site in a patient via manipulation of the delivery device, the delivery device extendable outside the patient when the anchor is implanted at the target site; and
an implant deliverable through the delivery device to the target site and implantable through the annular anchor, wherein the delivery device coupled to the annular anchor controls a trajectory of delivery of the implant into the target site,
wherein at least a portion of the circumference of the annular anchor comprises a chamfered lip extending inwardly from a proximal to a distal end of an annular portion of the annular anchor.

US Pat. No. 10,653,452

DYNAMIC SPINAL FIXATION SYSTEM, METHOD OF USE, AND SPINAL FIXATION SYSTEM ATTACHMENT PORTIONS

REVIVO MEDICAL, LLC, Lou...

1. An implant, comprising:a member with a superior end and an inferior end;
a first opening at the superior end, wherein the first opening comprises:
a recessed region positioned around the first opening, wherein the recessed region is inset into the member; and
a first relief positioned within at least a portion of the first opening, and wherein the first relief extends entirely through the recessed region;
wherein the first opening has a first longitudinal axis and the member has a second longitudinal axis and the first longitudinal axis is positioned transverse to the second longitudinal axis;
a second opening at the inferior end, wherein the second opening has a third longitudinal axis and the third longitudinal axis is positioned transverse to the second longitudinal axis of the member.

US Pat. No. 10,653,451

ARTICULATING SPINAL ROD SYSTEM

REFAI TECHNOLOGIES, L.L.C...

1. An articulating joint system, comprising:an articulating joint assembly including at least one articulating joint, the at least one articulating joint comprising:
a receptacle, comprising:
a first member; and
a second member coupled to the first member to form a cavity inside the coupled first member and second member and an opening extending into the cavity; and
a pivoting member, comprising:
a spherical shaped end configured to be received within the cavity;
a bearing member coupled to the spherical shaped end and extending through and away from the opening of the receptacle, the bearing member including a center opening, wherein the bearing member has a spherical shape, wherein the center opening at least partially bisects the bearing member, and wherein a central axis of the bearing member is positioned linear with a central axis of the spherical shaped end; and
a hinge member coupled to the bearing member with a pivot pin and received within the center opening, wherein an exterior surface of the hinge member is shaped to correspond to an exterior surface of the bearing member, and wherein the hinge member pivots about the pivot pin;
a plate; and
at least one rod system coupling the articulating joint assembly to the plate.

US Pat. No. 10,653,450

SURGICAL TOOL CONTROL DEVICES AND METHODS OF USING THE SAME

Boston Scientific Scimed,...

1. A medical device, comprising:a base member including a first end portion and a second end portion; and
an adjustment member being slideably and rotatably connected to the base member,
wherein the base member configured to extend in a first direction and the adjustment member configured to extend in a second direction, the second direction being substantially orthogonal to the first direction,
the base member includes a first surface portion and a second surface portion opposite the first surface portion, the first surface portion being disposed on a surface of an operating table and the second surface portion being adjacent to the adjustment member,
the adjustment member having a body portion and a coupling portion, the coupling portion being removably coupled to the body portion, the coupling portion being configured to couple a medical tool to the adjustment member, at least a portion of the medical tool being configured to be inserted into a vagina of a patient.

US Pat. No. 10,653,449

CANNULA SEALING

SURGICAL INNOVATIONS LIMI...

1. A surgical access device comprising a seal assembly comprising a plurality of part circular sealing members each attached to a common ring which is held within the device about its longitudinal axis and with the part circular sealing members being located radially inwards of the common ring in a stacked relationship, characterised in that the seal assembly comprises a single sheet of flexible material which is configured to be arranged in a single plane with the part circular sealing members in a non-overlapping relationship and in that the part circular sealing members are foldable, when not within the device, from a position radially outwards of the common ring to a position radially inwards of the common ring.

US Pat. No. 10,653,448

POWERED DRIVER ACTUATED BY FORCE ON DRIVESHAFT AND RELATED KITS, COMPONENTS, AND METHODS

TELEFLEX LIFE SCIENCES LI...

15. A driver configured to assist a user with inserting an intraosseous (IO) device into a bone, the driver comprising:a housing defining a primary portion extending between the distal end and the proximal end, and a handle portion extending from the primary portion;
a driveshaft extending outward from a distal end of the housing in a direction away from a proximal end of the housing;
a motor disposed in the housing;
a gearbox coupled to the motor and to the driveshaft such that activation of the motor will cause rotation of the driveshaft;
a battery configured to power the motor;
a switch disposed in the housing and coupled to the battery; and
a switch mount having a proximal end and a distal end, a shelf spaced from the proximal end of the switch mount, and a pair of stepped motor guides extending to a distal end of the switch mount and including steps;
where an application of a threshold force applied to a distal end of the IO device via the housing in a direction of an insertion site causes motor activation via operation of the switch, thus rotating the driveshaft and the IO device.

US Pat. No. 10,653,447

METHOD OF USING AN INTRADERMAL APPLICATOR FOR DELIVERING A SENSOR WITHIN THE SKIN

POP TEST LLC, Cliffside ...

1. A method of delivering a sensor to a subject's skin, the method comprising:administering an imaging agent to a subject, wherein the imaging agent collects in a target area of the subject's skin, wherein the target area is a reticular dermis of the skin of the subject, further wherein the imaging agent is a fluorescent agent;
providing a device for guiding an implanting of an applicator and/or sensor within the skin of the subject, the device comprising: a housing comprising:
at least one insertion port contiguous with an insertion channel that is formed at a predetermined angle within said housing, said channel having an opening that is adapted to rest against the skin;
an ultraviolet illuminator for illuminating said fluorescent agent that is previously positioned within the reticular dermis of the subject that is located underneath said housing;
a camera, said camera capturing an image of the skin, including the reticular dermis, located beneath said housing; and
a display, associated with said housing, that permits a user to view said image when passing an applicator and/or sensor through said channel such that a tip of said applicator and/or sensor is positioned within the reticular dermis for delivering the sensor therein;
applying the imaging device to the skin of the subject;
illuminating the skin with the illuminator, thereby causing the imaging agent to fluoresce;
using said display associated with said housing to adjust a focus of a confocal microscope into a plane of the fluorescence; and
inserting an applicator through the at least one insertion port into the target area of the subject, wherein the user uses said display to follow the insertion of the applicator, wherein when the tip of the applicator is in the plane of the focus, the applicator is in the target area.

US Pat. No. 10,653,446

TYMPANOSTOMY TUBE DELIVERY DEVICE WITH CUTTING DILATOR

TUSKER MEDICAL, INC., Me...

11. An apparatus, comprising:a body; and
a shaft assembly extending distally from the body, the shaft assembly including:
a tubular member disposed within the shaft assembly and having a cylindrical shape with an outer circumference; and
a plurality of leaves disposed at a distal end of the tubular member, wherein the plurality of leaves is movable between a collapsed position and an expanded position, the plurality of leaves including a first leaf including a sharp distal point configured to create an incision in a tympanic membrane of a patient and a second leaf including a blunt distal point, the first leaf extending around a greater portion of the outer circumference than the second leaf,
wherein the plurality of leaves define a plurality of longitudinally-extending gaps, each of the plurality of longitudinally-extending gaps disposed between two leaves of the plurality of leaves.

US Pat. No. 10,653,445

SENSOR INSERTION ASSEMBLY, SENSOR CARTRIDGE, AND INSERTER

Roche Diabetes Care, Inc....

1. A sensor insertion assembly, comprising: a sensor cartridge comprising an insertion needle configured for piercing the skin to create a puncture wound through which a sensor is inserted into the skin, the insertion needle and tip thereof disposed within a sealed sterile capsule; the sensor being within the sealed sterile capsule, wherein the sensor is within the insertion needle; and an inserter comprising a chamber for removably receiving the sensor cartridge, the inserter further comprising an actuator operable for actuating the insertion needle for inserting the sensor into a subject; wherein the sensor cartridge is operable for shielding the insertion needle upon removal of the sensor cartridge from the chamber and after inserting the sensor into the subject.

US Pat. No. 10,653,444

PERFORATING TROCAR

Merit Medical Systems, In...

1. A perforating trocar, comprising:an outer sleeve having a rigid tube; and
a mandrel having a rod, the rod being suitable for sliding in the outer sleeve, wherein the rod has a longitudinal groove formed in and along an exterior surface of the rod, the groove in the exterior surface of the rod extending from a distal end to a proximal end of the rod, wherein the mandrel further comprises a stopper at the proximal end of the rod, wherein the groove extends to the stopper, and wherein the stopper comprises a bore extending therethrough,
wherein the distal end of the rod comprises a perforating tip, wherein the groove extends to a distal end of the perforating tip, the perforating tip formed by bevels at the distal end of the rod, the distal end of the rod comprising first and second cutting ridges extending from the perforating tip to first and second positions, respectively, on an outside diameter of the rod, the second cutting ridge disposed on one face of the groove and being more inclined than the first cutting ridge with respect to the longitudinal axis of the rod.

US Pat. No. 10,653,443

ACCESS ASSEMBLY FOR ANTERIOR AND LATERAL SPINAL PROCEDURES

Integrity Implants, Inc.,...

1. An access assembly (10) for anterior, lateral and anterolateral spinal procedures comprising:a needle assembly (12), including a cannula (26) and a needle member (24), said needle member (24) having a point end (28), a second end (88) and a central portion (90) and an outer diameter, said second end including a stop member extending outwardly from said outer diameter;
said cannula (26) formed as a tubular member having a first end (84), a second end (86) and a central portion (80), a lumen (81) extending through said cannula (26), said lumen sized so that said cannula slides over said needle member (24) and said second end (86) of said cannula is adjacent said stop member;
a handle assembly (14) for providing manipulating said needle assembly (12) during insertion thereof, said handle assembly (14) including a clamp portion (30), said clamp portion (30) cooperating with said adjacently positioned stop member and said second end of said cannula for securing said handle assembly (14) to said needle assembly (12), said clamp portion (30) simultaneously securing said needle member (24) within said lumen (81) of said cannula (26) having said point (28) of said needle member (24) extending beyond an end point of said second end (86) of said cannula (26).

US Pat. No. 10,653,442

DRUG DELIVERY SYSTEMS AND METHODS

ALCYONE LIFESCIENCES, INC...

1. A drug delivery device, comprising:an elongate body having a fluid lumen formed therein; and
a fluid port formed in the drug delivery device, the fluid port being defined by a helical slit formed in a wall of the drug delivery device;
wherein the helical slit extends from an interior surface of the wall to an exterior surface of the wall of the delivery device to thereby radially deliver fluid to an exterior of the drug delivery device.

US Pat. No. 10,653,441

ATHERECTOMY WITH SUBINTIMAL SPACE

TERUMO KABUSHIKI KAISHA, ...

1. A method for treating a stenotic vessel, the method comprising:inserting a first dissecting member into a subintimal space of a blood vessel and a second dissecting device configured to be received within a lumen within the first dissecting device and inserted into the blood vessel in a bent state;
dissecting an inner side of the subintimal space from an outer side of the subintimal space over an entire circumference of the blood vessel with the first dissecting device; and
removing the dissected inner side of the subintimal space and a stenotic region attached to the inner side of the subintimal space from the blood vessel.

US Pat. No. 10,653,440

TIP FOR LEAD EXTRACTION DEVICE

Cook Medical Technologies...

1. A tip engaged with an elongated sheath member for extracting a pacemaker lead from an obstruction in a body vessel of a patient, said sheath member having a distal end and a passageway extending at least substantially therethrough, said tip comprising:a tip body having a proximal end, a distal end, and a passageway extending therethrough, said tip body proximal end engaged with said sheath member distal end such that said respective passageways are axially aligned and said pacemaker lead is extendable through said axially aligned passageways, said tip body distal end including an elongated portion having a diameter, and including a segment tapering inwardly from said elongated portion diameter toward a leading edge, said tapered segment having an outer surface decreasing linearly and terminating in said leading edge and configured to separate the pacemaker lead from the obstruction, a disruptor element disposed along an outer surface of said tip body elongated portion, the entirety of said disruptor element disposed proximal of at least said leading edge of said tapered segment along said outer surface, said disruptor element structured such that said tip disrupts said obstruction in a forward direction along a path of the tip as said tip is advanced over said pacemaker lead,
wherein said disruptor element comprises a plurality of helices disposed along and projecting outwardly from said outer surface in a side-by-side manner, wherein said plurality of helices each comprise a pair of side faces defining a constant cross-section therebetween along the entire length thereof and a distal-most end face extending perpendicularly outwardly from the outer surface of said elongated portion, and wherein the distal-most end face of each of said helices is disposed proximal of and spaced apart from both the leading edge and a junction of a proximal terminal end of said tapered segment with said elongated portion, and
wherein the tip body is movably disposable over a pacemaker lead disposed within the body vessel of the patient and is engagable with an obstruction within said body vessel.

US Pat. No. 10,653,439

PUMP MODULE

Medaxis AG, Baar (CH)

1. A pump module comprising a casing in which at least one pump piston is mounted in a reciprocating manner and provided with at least one sealing element which in a pumping operation sealingly abuts against a cylinder, and further comprising a locking element which is arranged on said casing and which in a parking position, in which said sealing element does not abut against said cylinder, interacts with a locking counter-element provided on said pump piston for fixing said pump piston in the parking position;wherein said locking element comprises a pawl formed integrally on the casing and elastically preloaded radially against the pump piston, and said locking counter-element comprises two radial projections provided at an axial distance from one another between which said locking element engages in the parking position.

US Pat. No. 10,653,438

AUTOMATED IMAGE-GUIDED TISSUE RESECTION AND TREATMENT

PROCEPT BIOROBOTICS CORPO...

1. A prostate resection apparatus comprising:a carrier having a proximal end and a distal end;
at least one energy source on the carrier spaced proximally to be positioned in a urethra for delivering energy radially outwardly; and
a processor comprising instructions configured:
to provide a plurality of images of a tissue on a display visible to a user, each image of said plurality comprising a plane of a three-dimensional representation of the tissue;
to receive input from the user to define a treatment profile along said each image of the plurality of images, the user input corresponding to an axial length of the treatment profile; and
to determine a three-dimensional treatment profile based on the treatment profile along said each of the plurality of images.

US Pat. No. 10,653,437

SURGICAL INSTRUMENT WITH TISSUE DENSITY SENSING

Ethicon LLC, Guaynabo, P...

1. An apparatus comprising:(a) an end effector comprising an ultrasonic blade, wherein the end effector is configured to deliver ultrasonic energy to a surgical site via the ultrasonic blade;
(b) an acoustic drivetrain comprising an ultrasonic transducer in acoustic communication with the ultrasonic blade;
(c) a sensor configured to measure an acoustic reaction generated by either the end effector or the acoustic drivetrain; and
(d) a control module, where the control module is configured to generate a first frequency at a first resonant frequency associated with the acoustic drivetrain utilizing the acoustic reaction of the end effector or the acoustic drivetrain under a first load during exemplary use, wherein the control module is configured to generate a second frequency at a resonant frequency associated with the acoustic drivetrain utilizing the acoustic reaction of the end effector or the acoustic drivetrain under a second load during exemplary use, wherein the control module is further configured to determine a shift from the first resonant frequency to the second resonant frequency associated with the acoustic drivetrain, wherein the control module is configured to generate a notification signal in response to determining the shift.

US Pat. No. 10,653,436

MEDICAL DEVICE FOR CUTTING

Boston Scientific Scimed,...

1. A medical device comprising:a member having a proximal end and a distal end;
an end-effector disposed at the distal end of the member, the end-effector including a first arm and a second arm, wherein the first arm is configured to pivot relative to the second arm, wherein radially inward facing edges of the first arm and the second arm are non-conductive such that upon application of an electrical current to the end-effector, the electrical current does not flow through the radially inward facing edges of the first arm and the second arm; and
an expandable element having a proximal end and a distal end, wherein the proximal end of the expandable element is coupled to a proximal end of the end-effector, the expandable element is movable between a radially-collapsed configuration and a radially-expanded configuration, the expandable element has a plurality of legs circumferentially spaced from one another, and distal ends of the plurality of legs converge toward one another.

US Pat. No. 10,653,435

MOTOR-DRIVEN SURGICAL CUTTING AND FASTENING INSTRUMENT WITH TACTILE POSITION FEEDBACK

Ethicon LLC, Guaynabo, P...

1. A surgical instrument system, comprising:an end effector, comprising:
an elongate channel;
a staple cartridge, comprising:
a plurality of staples; and
a plurality of staple drivers;
a clamping member pivotably connected to said elongate channel, wherein said clamping member is movable between an open position and a clamped position during a clamping motion; and
a firing member movable within said elongate channel to engage said staple drivers and deploy said staples from said staple cartridge;
a shaft comprising a shaft axis;
a closure drive;
a closure member operably connected to said closure drive, wherein said closure member is configured to translate in a proximal direction to pivot said clamping member to said clamped position; and
a motor-powered firing drive operably connected to said firing member, wherein said closure drive and said firing drive are independently actuatable.

US Pat. No. 10,653,434

DEVICES AND METHODS FOR REMOVING OBSTRUCTIVE MATERIAL FROM AN INTRAVASCULAR SITE

Imperative Care, Inc., C...

1. A system for removing embolic material from an intravascular site, comprising:an elongate, flexible tubular body, having a proximal end, a distal end, and a tubular side wall defining at least one lumen extending axially there through;
an axial restraint carried by the side wall and exposed to the lumen;
a rotatable core wire extendable through the lumen, the core wire having a proximal end and a distal end;
a limit carried by the core wire, the limit having a bearing surface for rotatably engaging the restraint; and
an agitator tip on the distal end of the core wire;
wherein the limit and the restraint are engageable to permit rotation of the core wire but limit distal advance of the tip relative to the tubular body; and
wherein the core wire is tapered from a larger diameter at a proximal point to a smaller diameter at the limit that is no more than about 30% of the larger diameter.

US Pat. No. 10,653,433

MEDICAL DEVICE AND METHOD FOR TREATMENT

TERUMO KABUSHIKI KAISHA, ...

1. A medical device configured to be inserted into a lumen of a living body, the medical device comprising:a shaft part;
an expandable part comprising a plurality of wires, the expandable part having a connecting part connected to a distal part of the shaft part;
the connecting part located at a proximal part of the expandable part and having an inner tube and an outer tube; and
wherein a distal end portion of the shaft part and a proximal end portion of the plurality of wires are connected between the inner tube and the outer tube.

US Pat. No. 10,653,432

OSTEOTOMY GUIDE

Wright Medical Technology...

1. A guide for a bone cut, comprising:a guide base having an inner wall defining an opening, the inner wall having a plurality of detents distributed around the opening, the guide base having a proximal surface adapted to contact a skin of a person;
an inner collar having one or more spring loaded devices extending outward therefrom in opposite directions, the inner collar mountable with the spring loaded devices fitting within one or more of the plurality of detents, the inner collar having an inner wall defining a bore for receiving a cutting tool, the inner collar configured to pivot the cutting tool about an axis, for cutting a bone, the axis lying along or parallel to a line along which the spring loaded devices lie; and
an outer sleeve rotatably mounted within the opening of the guide base, the outer sleeve having an inner surface, an outer surface, and a pair of apertures extending from the inner surface to the outer surface,
wherein the inner collar is pivotally mountable in the outer sleeve with the spring loaded devices extending through the apertures of the outer sleeve.

US Pat. No. 10,653,431

DRILL ASSEMBLIES AND METHODS FOR DRILLING INTO BONE

MEDOS INTERNATIONAL SARL,...

1. A drill assembly comprising:a shaft having a longitudinal axis and a distal end;
a drill tip disposed distally of the distal end of the shaft;
a flexible element disposed between the drill tip and the shaft, wherein the flexible element includes a plurality of wires twisted together, and the flexible element is configured to move from a substantially linear configuration aligned with the longitudinal axis to a curved configuration with respect to the longitudinal axis; and
a monolithic conformal covering disposed on the flexible element, having a thickness that varies along a length of the flexible element and that defines a flute extending helically around the flexible element, and configured to reduce diametric expansion of the flexible element due to compressive forces when the flexible element is in the curved configuration and is capable of transmitting bidirectional torque.

US Pat. No. 10,653,430

ARTERIAL COMPRESSION DEVICE AND METHODS OF USING THE SAME

CORMED LIMITED, Cheadle ...

1. An arterial compression device comprising:a band for securably fastening the arterial compression device around, a wrist of a subject;
a wrist plate having a first end and a second end, wherein the band is connected to the wrist plate at the first end and the second end;
a compression portion that is moveable toward or away from the wrist plate so as to selectively apply pressure to the radial artery of the subject, the compression portion being connected to the wrist plate;
an aperture permitting access to the ulnar artery of the subject when the arterial compression device is securably fastened around the wrist of the subject, wherein the aperture is formed by both the wrist plate and the band, and is bound on one side by an edge of the wrist plate and on an another side by an edge of the band, the aperture sized to provide substantially unobstructed access for at least one thumb tip to pass therethrough so as to temporarily occlude the ulnar artery.

US Pat. No. 10,653,429

ENDOSCOPIC SURGICAL CLIP APPLIER

COVIDIEN LP, Mansfield, ...

1. An apparatus for application of surgical clips to body tissue, the apparatus comprising:a handle assembly; and
a shaft assembly selectively connectable to the handle assembly and actuatable upon actuation of the handle assembly, the shaft assembly including:
a pair of jaws movable between a spaced-apart position and an approximated position;
an elongated spindle having a proximal portion configured to be coupled to an actuator of the handle assembly, and a distal portion operably coupled to the pair of jaws to selectively approximate the pair of jaws during distal movement of the spindle, the spindle defining a longitudinally-extending channel having a first portion, and a second portion extending at a non-zero angle relative to the first portion;
a first shaft disposed alongside the spindle and defining a longitudinally-extending channel having a first portion, and a second portion extending at a non-zero angle relative to the first portion of the channel of the first shaft;
a slidable member extending through each of the channels of the spindle and the first shaft, wherein a first distal movement of the spindle relative to the first shaft moves the slidable member with the spindle and through the first portion of the channel of the first shaft, and a second distal movement of the spindle relative to the first shaft moves the slidable member with the spindle and into the second portion of the channel of the first shaft and the first portion of the channel of the spindle, such that a third distal movement of the spindle relative to the first shaft moves the spindle distally relative to the slidable member; and
a pusher bar having a proximal portion fixedly coupled to the slidable member, and a distal portion configured to load a distal-most surgical clip into the pair of jaws during distal movement of the slidable member, via the first distal movement of the spindle, and remain in a distally advanced position during approximation of the pair of jaws.

US Pat. No. 10,653,428

ENDOSCOPIC SNARE COMBINED WITH A CLIP APPLIER

1. An elongated endoscopic apparatus for clipping then severing peduncular-style polyps characterized by stems extending out from an anatomical wall and terminating in bulb ends, comprising:an elongated flexible catheter having a generally cylindrical sidewall and extending between a dispensing end and a control end;
said catheter being formed with at least one conduit that defines a generally cylindrical hollow core that terminates in an opening through the dispensing end, said opening being spaced in an eccentric relationship with the dispensing end such that a smallest gap between the opening and the sidewall at the dispensing end defines a perigee gap along an apogee-perigee axis that intersects the centers of both the opening and the dispensing end;
an endoscopic clip loaded into the core proximate the opening in the dispensing end of the catheter, said clip comprising a C-shape characterized by a pair of elongated jaws mated together at a tail end, said clip being oriented in the core such that the jaws are opposed to one another flanking the apogee-perigee axis and the tail end trails behind the jaws when dispensed out the opening;
a clip applier for dispensing the clip out the opening; and
a snare provision disposed inside the core concurrently with the clip and controllable to reciprocate axially between extension and retraction strokes, wherein said clip is further oriented to be disposed between the snare provision and the perigee gap;
whereby clipping procedures are performed with portions of the sidewall of the catheter encompassing the perigee gap lie on or close to the anatomical wall such that the jaws are oriented to flank the stem and urge the snare provision to a plane or planes above the clip and below the bulb.

US Pat. No. 10,653,427

FIXATION DEVICES, SYSTEMS AND METHODS FOR ENGAGING TISSUE

EVALVE, INC., Santa Clar...

1. A system for fixation of leaflets of a heart valve comprising:an implantable fixation device comprising:
a first distal element and a second distal element,
a first proximal element moveable relative to the first distal element between a first position and a second position, and
a second proximal element moveable relative to the second distal element between a first position and a second position; and
a delivery device comprising:
a catheter having a proximal end portion and a distal end portion, the implantable fixation device releasably coupled to the distal end portion of the catheter, the catheter defining at least one lumen extending between the proximal end portion and the distal end portion,
a first proximal element line extending through the at least one lumen, the first proximal element line coupled to the first proximal element and actuatable to move the first proximal element between the first position and second position, and
a second proximal element line extending through the at least one lumen, the second proximal element line coupled to the second proximal element and actuatable to move the second proximal element between the first position and second position,
wherein the first proximal element line and the second proximal element line are independently actuatable.

US Pat. No. 10,653,426

THROMBORESISTANT COATINGS FOR ANEURYSM TREATMENT DEVICES

Incept, LLC, Campbell, C...

1. A device for insertion into a blood vessel lumen for treatment of an aneurysm, comprising:a generally cylindrical section comprising a plurality of struts forming interstitial gaps between the struts, the generally cylindrical section having a proximal face and a distal face and defining a device lumen extending along an axial direction from the proximal face to the distal face, the lumen being configured to allow blood flow through the device, the generally cylindrical section being configured to provide a radially outward counter force to compression adjacent the proximal face which is greater than a radially outward counter force to compression near a middle of the generally cylindrical section; and
a proximal tapered section comprising a plurality of struts extending from a circumference of the proximal face to a proximal apex,
wherein the proximal apex is radially aligned with the circumference of the proximal face or positioned radially outside the circumference of the proximal face, and
wherein the plurality of struts of the proximal tapered section extend from different points on the circumference of the proximal face in an axial and circumferential direction to the proximal apex, such that none of the plurality of struts cross through a cross-sectional area defined by the device lumen.

US Pat. No. 10,653,425

LAYERED BRAIDED ANEURYSM TREATMENT DEVICE

DePuy Synthes Products, I...

1. An implant comprising:a tubular braid comprising an open end, a pinched end, and a predetermined shape;
wherein, in the predetermined shape, the tubular braid comprises:
a first segment extending from the open end to a first inversion,
a second segment encircled by the open end such that the second segment is only partially surrounded by the first segment and extending from the first inversion to a second inversion, and
a third segment surrounded by the second segment and extending from the second inversion to the pinched end.

US Pat. No. 10,653,424

AIRWAY VALVE FOR IRREGULAR SHAPED AIRWAY

SPIRATION, INC., Redmond...

1. A valve comprising:a. a frame having:
i. a plurality of anchors and
ii. a plurality of struts;
b. a membrane connected to and spanning between each of the plurality of struts;
wherein the membrane provides a load on each of the plurality of struts and the membrane is sufficiently elastomeric to (1) extend between each of the plurality of struts in a free state without the membrane wrinkling and (2) upon restriction of one or more of the plurality of struts from the free state to a loaded state, the membrane flexes into contact with a passageway so that the membrane substantially seals the passageway; and
wherein the membrane has a modulus of elasticity of 0.1 GPa or less and 0.01 GPa or more,
wherein the membrane is a silicone polyurethane.

US Pat. No. 10,653,423

CATHETERS FOR EMERGENCY ENDOVASCULAR SURGERY AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS

University of Washington,...

1. A catheter sized and shaped for delivery to a major blood vessel of a human patient, the catheter comprising:a tapered tip including a distal apex;
a guide-wire opening at or near the distal apex;
a balloon seat proximal to the tip;
a balloon extending around at least a portion of the balloon seat;
an inflation opening positioned within the balloon;
a main shaft proximal to the balloon seat having a column strength from about 50% to about 500% of a column strength of a sheath encompassing at least a portion of the main shaft;
a hub proximal to the main shaft;
an inflation port proximal to the hub;
an inflation lumen extending along the main shaft between the inflation port and the inflation opening; and
a pressure-relief valve operably connected to the inflation lumen,
wherein, during operation, the catheter is configured to occlude the major blood vessel, and wherein the pressure-relief valve is configured to open at a threshold pressure between a relative pressure within the balloon necessary to occlude the blood vessel and a relative pressure within the balloon that would burst or otherwise injure the blood vessel,
wherein—
the catheter has a first outer diameter at the main shaft, a second outer diameter at the balloon seat, and a third outer diameter between the tip and the balloon seat,
the second outer diameter is less than the first outer diameter, and
the third outer diameter is about equal to or greater than the first outer diameter.

US Pat. No. 10,653,422

INTRA-ABDOMINAL PRESSURE TO PROMOTE HEMOSTASIS AND SURVIVAL

Arsenal Medical, Inc., W...

1. A kit for treating hemorrhage in a cavity of a patient, the kit comprising:a formulation comprising at least one liquid phase, the formulation configured to form a foam when disposed into the cavity, wherein the foam exerts a pressure on an interior boundary of the cavity, said pressure characterized by a transient peak value; and
instructions instructing a user in the application of the formulation.

US Pat. No. 10,653,421

INSERTION AID WITH INTERFERENCE FIT

Covidien LP, Mansfield, ...

1. A method of introducing a surgical instrument into a body cavity, the method comprising:coupling an insertion device to a retaining member of the surgical instrument by frictional engagement;
inserting the surgical instrument and the insertion device into the body cavity; and
advancing the retaining member of the surgical instrument within a shell assembly of the surgical instrument towards the insertion device to detach the insertion device from the surgical instrument.

US Pat. No. 10,653,420

COMPLIANT COMPENSATION FEATURES FOR END EFFECTOR OF SURGICAL STAPLING INSTRUMENT

Ethicon LLC, Guaynabo, P...

1. An apparatus, the apparatus comprising:(a) a body assembly;
(b) a shaft extending distally from the body assembly;
(c) an end effector attached to the shaft, wherein the end effector comprises:
(i) a jaw, and
(ii) an anvil pivotable from an open position to a closed position relative to the jaw, wherein the anvil comprises a lateral edge located at a first lateral position; and
(d) a cartridge, wherein the cartridge comprises:
(i) a deck comprising an upper surface facing toward the anvil in the closed position, wherein the deck defines a plurality of openings,
(ii) a plurality of staples located within the plurality of openings, wherein each staple in the plurality of staples comprises a pair of legs extending above the upper surface of the deck,
(iii) a compressible buttress located on the upper surface of the deck, wherein portions of the legs of the staples are disposed in the compressible buttress,
(iv) a peripheral member extending above the upper surface of the deck, laterally adjacent to the compressible buttress, and
(v) a pinching surface associated with the peripheral member, wherein the pinching surface is located at a height extending above a height of the legs of the plurality of staples, wherein the first lateral position of the lateral edge of the anvil is laterally aligned with the pinching surface such that the lateral edge and the pinching surface share a common lateral position.

US Pat. No. 10,653,419

SURGICAL INSTRUMENT WITH AN ACTUATION LOCKOUT

C.R. Bard, Inc., Murray ...

1. A method for operating a surgical instrument, the method comprising:moving an articulation control associated with an elongated shaft assembly between a first position in which an articulable portion of the elongated shaft assembly is arranged in a first articulation position at a first angle and a second position in which the articulable portion of the elongated shaft assembly is arranged in a second articulation position at a second angle different from the first angle, wherein the articulation control includes a blocking portion;
aligning the blocking portion of the articulation control with a locking member of a fastener deployment system when the articulation control is in the first position; and
moving the blocking portion of the articulation control out of alignment with the locking member when the articulation control is in the second position.

US Pat. No. 10,653,418

SURGICAL INSTRUMENT WITH ARTICULATING TOOL ASSEMBLY

COVIDIEN LP, Mansfield, ...

1. An articulation mechanism for articulating a surgical tool assembly, the articulation mechanism comprising:a housing defining a longitudinal axis, the housing including a recessed portion having a first diameter, and a stepped portion having a second diameter;
an articulation spindle rotatably disposed within the housing and having an interface member, the articulation spindle including:
a cylindrical member having a bottom surface, the interface member extending downwardly from the bottom surface; and
a flange disposed on top of the cylindrical member and extending radially outward from the cylindrical member, wherein the cylindrical member mechanically interfaces with the recessed portion and the flange mechanically interfaces with the stepped portion; and
a first articulation link having a proximal and a distal end configured to be coupled to a proximal end of a second articulation link of a surgical tool assembly, the proximal end of the first articulation link defining a slit and the interface member movably received in the slit, wherein translational movement of the interface member through the slit effects an axial movement of the first articulation link and the slit thereof along the longitudinal axis.

US Pat. No. 10,653,417

SURGICAL INSTRUMENT

Ethicon LLC, Guaynabo, P...

1. A surgical instrument, comprising:an end effector;
a firing member configured to move through at least a portion of the end effector to eject staples from a staple cartridge supported by the end effector;
a drive system connected to the firing member;
a variable speed electric motor connected to the drive system;
a firing trigger configured to actuate a firing motion when the firing trigger is drawn toward a handle of the surgical instrument; and
a pivot pin coupled to the firing trigger, wherein:
the firing trigger is mechanically uncoupled from the drive system; and
a positive rotational speed of the variable speed electric motor varies with an amount of force exerted on the pivot pin by the firing trigger.

US Pat. No. 10,653,416

POWERED SURGICAL INSTRUMENT

Covidien LP, Mansfield, ...

1. A transmission for a surgical tool, the transmission comprising:a housing;
a first actuator configured to rotate an end effector of the surgical tool;
a second actuator configured to move a first jaw of an end effector of the surgical tool relative to a second jaw of the end effector of the surgical tool;
a first input disposed at least partially within the housing; and
a second input disposed at least partially within the housing, the second input moveable between a first position in which the first input is engaged with the first actuator and a second position in which the first input is disengaged from the first actuator and the first input is engaged with the second actuator.

US Pat. No. 10,653,415

METHODS AND APPARATUS HAVING BOWSTRING-LIKE STAPLE DELIVERY TO A TARGET TISSUE

Rotation Medical, Inc., ...

1. A method for attaching a sheet-like implant to a target tissue, the method comprising:advancing a staple and a staple delivery device therefore to a staple deployment site,
wherein the staple comprises a first arm having a proximal end and a distal end, and a second arm having a proximal end and a distal end with a bridge extending from the proximal end of the first arm to the proximal end of the second arm, a first fluke of the staple having a proximal end attached to the distal end of the first arm, and a second fluke of the staple having a proximal end attached to the distal end of the second arm,
wherein the staple delivery device comprises a staple push rod configured and adapted to engage the staple, the staple push rod of the staple delivery device including a shaft, a first stake and a second stake, each stake having a distal portion and a proximal portion, a proximal end of the proximal portion of each stake being fixed to a distal end of the shaft, the distal portion of the first stake extending into a first passage defined by the first fluke, and the distal portion of the second stake extending into a second passage defined by the second fluke,
wherein the staple push rod has a first constrained configuration in which the distal portion of the first stake and the distal portion of the second stake are separated by a first distance and the staple push rod has a second unconstrained configuration in which the distal portion of the first stake and the distal portion of the second stake are separated by a second distance, the second distance being greater than the first distance;
positioning the staple and the staple delivery device in the first constrained configuration with the distal portion of the first stake and the distal portion of the second stake proximate tissue to be stapled;
advancing the staple push rod toward the tissue to be stapled while allowing the distal portion of the first stake and the distal portion of the second stake to transition toward the second unconstrained configuration as the first fluke and the second fluke contact and then penetrate the tissue to be stapled; and
continuing to advance the staple push rod toward the tissue to be stapled until the bridge of the staple extends tautly between the distal portion of the first stake and the distal portion of the second stake.

US Pat. No. 10,653,414

ANVIL ASSEMBLY WITH SLIDING SLEEVE

Covidien LP, Mansfield, ...

1. An anvil assembly comprising:an anvil center rod assembly;
a head assembly pivotally secured to the anvil center rod assembly and movable between an operative position and a tilted position, the head assembly including a housing and a post extending from the housing, the post including a tab; and
a sleeve positioned about the anvil center rod assembly and movable between a distal position and a proximal position, the sleeve defining an opening positioned to receive the tab when the head assembly is in the operative position and the sleeve is in the distal position, wherein receipt of the tab within the opening secures the sleeve in the distal position.

US Pat. No. 10,653,413

SURGICAL INSTRUMENTS WITH AN END EFFECTOR THAT IS HIGHLY ARTICULATABLE RELATIVE TO AN ELONGATE SHAFT ASSEMBLY

Ethicon LLC, Guaynabo, P...

1. A surgical instrument comprising:an elongate shaft assembly defining a shaft axis and comprising a distal end;
a surgical end effector comprising a proximal end that is pivotally coupled to said elongate shaft assembly for selective pivotal travel about an articulation axis that extends transversely relative to said shaft axis; and
an articulation link arrangement configured for rotation relative to said shaft axis such that rotation of said articulation link arrangement induces articulation of said surgical end effector about said articulation axis relative to said elongate shaft assembly, said articulation link arrangement comprising:
a central articulation link movably coupled to said distal end of said elongate shaft assembly; and
an end effector driver link comprising a proximal driver link end that is pivotally coupled to said central articulation link and a distal driver link end that comprises an axial slot that is configured to slidably receive therein an end effector attachment member such that said end effector driver link is operably coupled to said surgical end effector for selective pivotal and longitudinal travel relative thereto, and wherein said surgical instrument further comprises an articulation driver supported for selective longitudinal travel relative to said elongate shaft assembly in a distal direction and a proximal direction, said articulation driver operably coupled to said central articulation link.

US Pat. No. 10,653,412

PRE-TIED SURGICAL KNOTS FOR USE WITH SUTURE PASSERS

Ceterix Orthopaedics, Inc...

1. A method of repairing a meniscus in a knee joint, the meniscus having an apex, a superior surface adjacent a femur, and an inferior surface adjacent a tibia, the method comprising:using a suture passer to pass a suturing element from the inferior surface of the meniscus, through the meniscus, to the superior surface of the meniscus, across the inferior surface of the meniscus, and again back through the meniscus from the inferior surface to the superior surface of the meniscus.

US Pat. No. 10,653,411

IMPLANTS, TOOLS, AND METHODS FOR TREATMENTS OF PELVIC CONDITIONS

Boston Scientific Scimed,...

1. An apparatus comprising:a first arm having an extending member, the first arm including a tube defining a lumen and configured to receive a length of a suture material, the lumen configured to receive a pressurized fluid that travels from a first end portion of the tube of the first arm to a second end portion of the tube of the first arm; and
a second arm defining an aperture, the second arm being rotatably coupled to the first arm and being configured to rotate with respect to the first arm, the second arm including a tube defining a lumen and configured to receive a length of a suture material, the lumen configured to receive a pressurized fluid that travels from a first end portion of the tube of the second arm to a second end portion of the tube of the second arm,
wherein the aperture of the second arm is configured to receive at least a portion of the extending member of the first arm.

US Pat. No. 10,653,410

SOFT TISSUE FIXATION DEVICES AND METHODS

Howmedica Osteonics Corp....

1. A method of implanting a fixation device in a targeted surgical site, the method comprising:engaging the fixation device on a forked end of a distal portion of an inserter, the forked end having an I-beam shape and having opposing projections positioned distally of a central support and defining a cut-out portion of the central support, the fixation device including a filamentary fixation device formed of filament;
inserting the distal portion of the inserter and the filamentary fixation device within the targeted surgical site; and
implanting the filamentary fixation device within the targeted surgical site.

US Pat. No. 10,653,409

DEVICES AND METHODS FOR ANCHORING TISSUE

CROSSROADS EXTREMITY SYST...

1. A suture anchor assembly comprising:a base member having a proximal end and a distal end;
a delivery tube extending from the distal end of the base member, the delivery tube having a proximal end, a distal end, a longitudinal axis extending between the proximal end and the distal end, and a longitudinal passage;
an ejector having a proximal end and a distal end, the ejector being positioned within the delivery tube for axial translation between a first position in which the distal end of the ejector is proximal to the distal end of the delivery tube and a second position in which the distal end of the ejector is distal to the first position, the ejector being moveable by a user to the second position;
a button coupled to the proximal end of the ejector;
a safety device operable to prevent movement of the ejector by a user to the second position by preventing user contact with the button; and
a suture anchor positioned in the delivery tube distal to the distal end of the ejector.

US Pat. No. 10,653,408

MULTIPLE SPINAL SURGICAL PATHWAYS SYSTEMS AND METHODS

Warsaw Orthopedic, Inc., ...

1. A method for surgically treating the spine of a patient, the method comprising:positioning a patient on a surgical table;
providing a first opening into a posterior portion of the patient;
providing a second opening into a lateral portion of the patient;
inserting a first manipulation device through the first opening into the patient to contact the spine in a first direction that is transverse to the coronal plane of the patient, the contact of the first manipulation device to the spine including fixed engagement of the first manipulation device to a first vertebral body;
inserting a second manipulation device through the second opening into the patient to contact the spine in a second direction that is transverse to the sagittal plane of the patient, the contact of the second manipulation device to the spine including fixed engagement of the second manipulation device to a second vertebral body; and
manipulating the first and second manipulation devices to move the first vertebral body and the second vertebral body relative to one another;
wherein the first and second openings are accessible simultaneously.

US Pat. No. 10,653,407

SURGICAL RETRACTOR

NuVasive, Inc., San Dieg...

1. A retractor assembly for tissue retraction at the site of an incision, the retractor assembly comprising:an arcuate frame member that extends around an arc of 270°;
a groove running along a proximal surface of the frame member including:
a plurality of expanded portions along the proximal surface, and
a plurality of narrower portions along the proximal surface;
a mobile carriage configured to initially engage with at least one of the plurality of expanded portions of the groove and subsequent to an initial engagement, engage with at least one of the plurality of narrower portions of the groove to allow the carriage to translate along the groove, the mobile carriage including:
a blade post holder attached to a blade post; and
a carriage locking mechanism configure to allow the blade post six degrees of freedom of movement relative to the frame member when in an unlocked position, and to prohibit movement relative to the frame member when in a locked position except translation along the groove.

US Pat. No. 10,653,406

LAPAROSCOPIC RETRACTOR DEVICES

Mayo Foundation for Medic...

1. A tissue retraction apparatus comprising:a tissue cradling member comprising a thin and flexible material having a distal end portion and a proximal end portion, the tissue cradling member defining a longitudinal length and a lateral width;
an elongate structural element affixed to the distal end portion of the tissue cradling member and affixed to the proximal end portion of the tissue cradling member, the elongate structural element extending along the longitudinal length of the tissue cradling member;
a distal coupling member affixed to the distal end portion of the tissue cradling member or to the elongate structural element near the distal end portion of the tissue cradling member; and
a proximal coupling member affixed to the proximal end portion of the tissue cradling member or to the elongate structural element near the proximal end portion of the tissue cradling member,
wherein the distal coupling member and the proximal coupling member are selectively coupleable to each other after wrapping the tissue cradling member around tissue in a cradle-like fashion,
wherein the retraction apparatus is reconfigurable between a low profile delivery configuration and an expanded deployed configuration, and wherein the retraction apparatus is configured to be contained within a delivery sheath when the retraction apparatus is in the low profile delivery configuration.

US Pat. No. 10,653,405

SKIN RETRACTOR AND PROP DEVICE AND METHODS OF USE

The Penn State Research F...

1. A retractor and prop device, comprising:a first member;
a second member;
wherein:
the first and second members are moveable relative to each other about at least one junction, each junction of the at least one junction is configured to at least one of statically, resiliently, and pivotally connect the first member and the second member together such that the first member is movable relative to the second member via motion about the at least one junction;
each junction of the at least one junction is configured to provide a biasing force to move the first member and the second member away from each other to position the device in an open state; and
the first member is movable relative to the second member about the at least one junction from the open state to a closed state;
a first arm, a second arm, and a third arm extending from adjacent a first side of the first member to adjacent a first side of the second member, the second arm being located between the first and third arms: and
a fourth arm, a fifth arm, and a sixth arm extending from adjacent a second side of the first member to adjacent a second side of the second member, the second side of the first member being opposite the first side of the first member, the second side of the second member being opposite the first side of the second member, the fifth arm being located between the fourth and sixth arms,
the first arm being aligned with the fourth arm, the second arm being aligned with the fifth arm, and the third arm being aligned with the sixth arm;
wherein an intermediate portion of the first arm defines a first junction, an intermediate portion of the second arm defines a second junction, an intermediate portion of the third arm defines a third junction, an intermediate portion of the fourth arm defines a fourth junction, an intermediate portion of the fifth arm defines a fifth junction, and an intermediate portion of the sixth arm defines a sixth junction;
the second junction being located between the first and third junctions;
the fifth junction being located between the fourth and sixth junctions;
the fifth junction being aligned with the second junction, the first junction being aligned with the fourth junction, and the third junction being aligned with the sixth junction; and
the first member being movable relative to the second member between the open state and the closed state about the first junction, the second junction, the third junction, the fourth junction, the fifth junction, and the sixth junction.

US Pat. No. 10,653,404

BIDIRECTIONAL CROSS-MIDLINE RETRACTOR/STABILIZER FOR EXCESSIVE AND/OR REDUNDANT TISSUE

GSQUARED MEDICAL LLC, Br...

1. A retractor/stabilizer for repositioning and stabilizing excessive and/or redundant tissue; the retractor/stabilizer comprising a top layer and a backing layer; the top layer having an adhesive applied thereto which is exposed when the backing layer is separated from the top layer to enable the top layer to be applied to a surface; the retractor/stabilizer comprising:a body having a top edge, side edges and a bottom edge; said body comprising a positioning section and a main section; said main section comprising a main body portion and first and second anchor lobes extending from a main body portion; whereby said body is generally Y-shaped and outer edges of said first and second lobes are spaced outwardly from side edges of said positioning section and main body portion;
a lower grasping panel proximate a lower edge of said body and proximate an outer end of said lower edge;
at least one upper protected grasping/holding area located at an end of at least one of said anchor lobes such that said grasping/holding area is laterally offset from an edge of said lower grasping panel, said lower grasping panel being proximate a side of said body opposite said upper grasping/holding area such that when said retractor/stabilizer is stretched by pulling on said at least one protected grasping/holding area, said retractor will be stretched in a direction offset from a vertical axis of said retractor/stabilizer;
said at least one upper protected grasping/holding area and said lower grasping panel each being defined in part by a back cut separating the backing layer of the lower grasping panel and the backing layer of the at least one grasping area from the backing layer of the body, the backing layer of the body defining at least one removable panel; whereby the backing layer of the lower grasping panel and the backing layer of the at least one grasping area remains with the at least one protected grasping/holding area and said lower grasping panel when the backing layer is removed from the body of the retractor/stabilizer.

US Pat. No. 10,653,403

MICROGRAFT FOR THE TREATMENT OF INTRACRANIAL ANEURYSMS AND METHOD FOR USE

Neurogami Medical, Inc., ...

1. A method for treating an intracranial aneurysm comprising the steps of:providing an occluding device having a lumen therein, the occluding device pre-set to a non-linear configuration to enhance packing of the aneurysm and composed of a non-expanding absorbent textile structure;
providing a delivery member;
inserting the delivery member with the occluding device into the aneurysm, the delivery member extending into the lumen of the occluding device and retaining the occluding device during delivery of the occluding device to the aneurysm and blood enters through a distal end of the lumen of the occluding device when the occluding device is inserted into the aneurysm; and
retracting the delivery member proximally within the lumen of the occluding device to provide space for blood flow in the lumen of the occluding device as blood displaces the delivery member.

US Pat. No. 10,653,402

CARDIAC INJURY DEVICE

UNITY HEALTH TORONTO, To...

1. A device for temporary management of a wound, comprisinga. a shaft having a first end portion and a second end portion and a shaft axis extending therebetween;
b. a blood flow blocking membrane at the first end portion for blocking blood flow through the wound, the blood flow blocking membrane having a first face facing towards the second end portion, an opposed second face facing away from the second end portion, a central portion adjacent the shaft, and a peripheral portion, the blood flow blocking membrane being resiliently flexible and movable between at least a first collapsed state wherein the membrane is flexed to move the peripheral portion axially towards the second end portion and radially inwardly towards the shaft axis for inserting the blood flow blocking membrane through the wound, a deployed state wherein, relative to the first collapsed state, the peripheral portion is moved away from the second end portion and radially outwardly for blocking blood flow through the wound, and a second collapsed state wherein, relative to the deployed state, the membrane is flexed to move the peripheral portion axially away from the second end portion and radially inwardly towards the shaft axis for removing the blood flow blocking membrane from the wound; and
c. an abutment member mounted to the shaft and axially movable along the shaft towards and away from the blood flow blocking membrane for abutting the wound and holding the blood flow blocking membrane adjacent the wound, wherein the blood flow blocking membrane has a membrane stiffness, and the abutment member has an abutment member stiffness greater than the membrane stiffness.

US Pat. No. 10,653,401

MEDICAL DEVICE FOR REPAIRING SOFT TISSUE AND METHOD OF USING SAME

1. A medical device for repairing soft tissue, comprising:a cannulated probe formed from a single tubular wall defining a periphery of the cannulated probe and a single lumen therethrough, the cannulated probe positionable about a tear in the soft tissue, the single tubular wall of the cannulated probe forming a needle configured to penetrate tissue at a distal end, the single tubular wall having an inlet at a proximal end and at least one outlet about the distal end with the single lumen therethrough, the inlet connected to an adhesive source to receive an adhesive therein and deliver the adhesive through the single lumen to the at least one outlet, the at least one outlet positionable about the tear to emit the adhesive about the tear;
a stop adjustably disposed about a periphery of the single tubular wall of the cannulated probe a distance from the inlet, the stop terminating advancement of the cannulated probe into the soft tissue and preventing further insertion when a delivery portion of the cannulated probe is positioned about the soft tissue to deliver the adhesive about the tear; and
a v-shaped clip comprising an upper plate and a lower plate hingedly connected to the upper plate to define an opening to receive the soft tissue therein and grasp the soft tissue therebetween, wherein the upper plate is configured to fit over a planar surface of the soft tissue having the tear and the lower plate is configured to fit over an opposing planar surface of the soft tissue opposite the tear to secure the opposing planar sides of the tissue, the cannulated probe disposable through the v-shaped clip,
wherein the single lumen extends the length of the single tubular wall of the cannulated probe between the inlet and the outlet.

US Pat. No. 10,653,400

SPECIMEN RETRIEVAL DEVICE

Covidien LP, Mansfield, ...

1. A specimen retrieval device comprising:a deployment assembly including,
an insertion tube;
a shaft slidably receivable through the insertion tube;
a handle disposed on a proximal end portion of the shaft; and
a support assembly disposed on a distal end portion of the shaft; and
a specimen retrieval bag supported by the deployment assembly, the specimen retrieval bag including,
a pouch including a pouch portion supported by the support assembly and a tail portion extending from the pouch portion to the handle and secured to the handle; and
a closure cord extending through the pouch portion for cinching the pouch portion.

US Pat. No. 10,653,399

MEDICAL OR DENTAL INSTRUMENT WITH A TEMPERATURE-MEASURING DEVICE

1. A medical handpiece, comprisinga handpiece head having an outer shell defining an inner volume,
a tool holder device for releasably holding a tool that can be connected to the handpiece, wherein the tool holder device is moveably arranged in the inner volume,
at least one bearing unit operatively connected to the tool holder device to moveably support the tool holder device, wherein the at least one bearing unit is arranged in the inner volume,
a drive device for setting in motion a tool that can be connected to the tool holder device,
an electrical temperature sensor of a temperature-measuring device for measuring a temperature of the at least one bearing unit, wherein the electrical temperature sensor is arranged in the inner volume of the handpiece head, and wherein the electrical temperature sensor comprises an electric resistor having a material whose electric resistance or dynamic resistance is variable as a function of temperature, and
an electric and signal line connecting the temperature sensor of the temperature-measuring device to a unit having
(i) a current or voltage source to supply a constant electric measuring current to the temperature sensor, wherein a temperature measuring signal comprises a value of the electric measuring current sent from the current or voltage source over the temperature sensor or a change in the value of the electric measuring current sent from the current or voltage source over the temperature sensor, which is indicative of the temperature of the at least one bearing unit, and
(ii) an evaluation unit for evaluating the temperature measuring signal, and a regulating or control unit for temperature-dependent regulation or control of the medical handpiece based on the temperature measuring signal,wherein the electric and signal line extends out of the handpiece head to connect to the unit.

US Pat. No. 10,653,398

ADAPTER ASSEMBLIES FOR SURGICAL DEVICES

Covidien LP, Mansfield, ...

1. A surgical device comprising:a handle;
a tool assembly; and
an adapter assembly interconnecting the handle and the tool assembly, the adapter assembly including:
a base member defining a longitudinal axis;
a housing rotatably secured to the base member, the housing rotatable in relation to the base member between a plurality of positions, rotation of the housing affecting a position of the tool assembly relative to the handle; and
a locking mechanism supported on the housing, the locking mechanism including:
a locking member moveable from a locked position in which a lock of the locking member is engaged with the base member to secure the housing in one of the plurality of positions to an unlocked position in which the housing is rotatable in relation to the base member; and
a button positioned on the base member and depressible to translate the locking member in a direction parallel to the longitudinal axis of the base member from the locked position to the unlocked position.

US Pat. No. 10,653,397

VIAL USEABLE IN TISSUE EXTRACTION PROCEDURES

Gallant Pet, Inc., La Jo...

1. A tissue extraction vial comprising:a container;
a cap for the container;
a blade configured to capture a tissue sample, the blade attached to the cap; and
a needle-penetrable septum adapted to provide access into the container;
wherein an end of the blade extends outside a periphery of the cap so as to be exposed for capturing a tissue sample;
wherein the blade has a length extending outside the periphery of the cap; and
wherein the length is entirely within the container without the blade passing through the needle-penetrable septum when the cap is mated to the container.

US Pat. No. 10,653,396

MULTI-SYNCHRONIZATION POWER SUPPLY AND ULTRASOUND SYSTEM WITH SAME

Siemens Medical Solutions...

1. A multi-synchronization power supply comprising:a microprocessor configured to receive frequency information indicative of a plurality of frequencies and to output a control signal based on the frequency information;
a clock signal generating unit configured to receive a reference synchronization clock signal and to generate a plurality of synchronization clock signals corresponding to the plurality of frequencies by frequency-dividing the reference synchronization clock signal based on the control signal; and
a plurality of DC-DC converters configured to receive the plurality of synchronization clock signals and a reference DC voltage, and to generate a plurality of DC voltages from the reference DC voltage based on the plurality of synchronization clock signals.

US Pat. No. 10,653,395

TRANSMIT POWER BASED ON HARMONIC TO FUNDAMENTAL RELATIONSHIP IN MEDICAL ULTRASOUND IMAGING

Siemens Medical Solutions...

1. A method for setting transmit power in medical diagnostic ultrasound imaging to ensure patient safety, the method comprising:measuring, with an ultrasound scanner, a fundamental response of tissue at a location in a patient, the location being selected to be at a deepest location of a field of view or region of interest in the patient;
measuring, with the ultrasound scanner, a harmonic response at the location;
calculating a ratio of the fundamental and harmonic responses from the location at the deepest location of the field of view or the region of interest;
setting a transmit power of a transmitter of the ultrasound scanner as a function of the ratio of the fundamental and harmonic responses such that harmonic information for imaging the tissue is provided for the field of view or region of interest; and
imaging the tissue with the harmonic information in the field of view or region of interest in the patient with the ultrasound scanner using the transmit power.

US Pat. No. 10,653,394

MEASURING OXYGENATION CHANGES IN TISSUE AS A MARKER FOR VASCULAR FUNCTION

Circle Cardiovascular Ima...

1. A method of assessing microvascular or macrovascular function in an individual comprising:providing baseline imaging data for displaying a baseline image of tissue;
providing test imaging data for displaying a plurality of test images of the tissue, at least a portion of the test imaging data having been acquired while oxygenation or blood flow in the tissue is altered in response to a stress event;
registering the test images against the baseline image, providing a plurality of registered images;
assessing at least one of oxygenation or blood flow and their changes in the tissue in response to a stress event by comparing the plurality of registered images;
wherein an abnormal response to the at least one of oxygenation or blood flow in the tissue is indicative of reduced microvascular or macrovascular function in the tissue.

US Pat. No. 10,653,393

INTRAVASCULAR ULTRASOUND IMAGING WITH FREQUENCY SELECTIVE IMAGING METHODS AND SYSTEMS

ACIST MEDICAL SYSTEMS, IN...

1. A method for generating an intravascular ultrasound image, the method comprising the steps of:emitting acoustic energy from an ultrasound transducer at a first frequency and receiving a backscatter of the acoustic energy at the ultrasound transducer to acquire a plurality of first frequency data vectors representing one or more items in an imaging view at the first frequency, wherein each data vector comprises ultrasound data;
emitting acoustic energy from the ultrasound transducer at a second frequency and receiving a backscatter of the acoustic energy at the ultrasound transducer to acquire a plurality of second frequency data vectors representing one or more items in the imaging view at the second frequency, wherein each data vector comprises ultrasound data, and wherein the first frequency is greater than the second frequency;
forming, from the plurality of first frequency data vectors, a first set of data vectors comprising ultrasound data at the first frequency;
forming, from the plurality of second frequency data vectors, a second set of data vectors comprising ultrasound data at the second frequency;
applying a first filter to the first set of data vectors to form a first modified data set, wherein applying the first filter to the first set of data vectors comprises applying a smoothing filter to the first set of data vectors to form the first modified data set, wherein applying the smoothing filter to the first set of data vectors comprises constructing a first pyramid in which a first level of the first pyramid includes an image at a first resolution and a second level of the first pyramid includes the image at a second resolution, the first resolution being a greater resolution than the second resolution, wherein the image included in the first level of the first pyramid is based on the first set of data vectors and the image included in the second level of the first pyramid is based on the image included in the first level of the first pyramid;
applying a second filter to the second set of data vectors to form a second modified data set, wherein applying the second filter to the second set of data vectors comprises applying a smoothing filter to the second set of data vectors to form the second modified data set, wherein applying the smoothing filter to the second set of data vectors comprises constructing a second pyramid in which a first level of the second pyramid includes an image at a first resolution and a second level of the second pyramid includes the image at a second resolution, the first resolution being a greater resolution than the second resolution, wherein the image included in the first level of the second pyramid is based on the second set of data vectors and the image included in the second level of the second pyramid is based on the image included in the first level of the second pyramid;
determining a frequency response of one or more items in the imaging view based on the first and second modified data sets; and
outputting the intravascular ultrasound image on a display based on the frequency response of one or more items in the imaging view.

US Pat. No. 10,653,392

ULTRASOUND IMAGING USING APPARENT POINT-SOURCE TRANSMIT TRANSDUCER

MAUI IMAGING, INC., San ...

1. An ultrasound imaging system comprising:a first apparent point-source transmit transducer shaped as a spherical section having a spherical center point, the first apparent point-source transmit transducer configured to transmit a three-dimensional semi-spherical pulse into a target object to be imaged;
a first plurality of receive transducer elements configured to receive echoes of the three-dimensional semi-spherical pulse;
a second plurality of receive transducer elements configured to receive echoes of the three-dimensional semi-spherical pulse;
a computing system configured to control transmission of the three-dimensional semi-spherical pulse and to determine a position of reflectors within the object based on a known position of the spherical center point of the apparent point-source transmit transducer, known positions of the elements of the first and second pluralities of receive transducer elements, a time at which the three-dimensional semi-spherical pulse was transmitted, and times at which the echoes are received, the computing system being further configured to calculate a total path distance as a sum of a first distance between the spherical center point and the target object and a second distance between the target object and the receive transducer element, wherein calculating the total path distance comprises adding an apparent path segment representing a distance from a convex transmit transducer surface of the apparent point-source transmit transducer to the spherical center point, and determining a locus of possible points at which the target object may lie.

US Pat. No. 10,653,391

SUBSTANTIALLY ACOUSTICALLY TRANSPARENT AND CONDUCTIVE WINDOW

Muffin Incorporated, Wes...

18. A medical device, comprising:a transducer for emitting and/or receiving an ultrasound beam, the ultrasound beam adapted to rotate around at least a portion of the device;
a housing containing the transducer and having an acoustically transparent acoustic window;
wherein the acoustic window also has at least one property from the group consisting of:
conductivity sufficient to carry electrical signals to and from the transducer, and
a variation in acoustic impedance and/or acoustic attenuation sufficient for registration of images obtained by the device;
the housing having a wall through which at least part of the ultrasound beam passes, the wall having an inner surface and an outer surface;
an ultrasound control system electronically connected to the transducer for receiving and assessing electronic signals from the transducer representing one or more qualities of ultrasound energy that has traveled along a path of the ultrasound beam;
a first film of conductive material in the acoustic window forming a first conductor, the first conductor being electronically connected to the transducer; and
a second film of conductive material in the acoustic window forming a second conductor, the second conductor being electronically connected to the transducer and electronically insulated from the first conductor, wherein one of the first and second films is on the inner surface of the wall, and the other of the first and second films is on the outer surface of the wall.

US Pat. No. 10,653,390

ULTRASONIC DEVICE, ULTRASONIC PROBE, ELECTRONIC APPARATUS, AND METHOD FOR MANUFACTURING ULTRASONIC DEVICE

Seiko Epson Corporation, ...

1. An ultrasonic device comprising:a substrate including ultrasonic elements configured to transmit and receive ultrasound;
a cable electrically connected to the ultrasonic elements and mounted on the substrate:
an acoustic lens having a plurality of projecting portions projecting toward the substrate, the plurality of projecting portions each having an end surface facing one of the substrate and the cable and connected to the one of the substrate and the cable; and
an acoustic matching unit located between the substrate and the acoustic lens, wherein the plurality of projecting portions are aligned along an outer perimeter of the substrate, and
a ratio of a total length of the plurality of projecting portions provided in a place where the cable is installed with respect to a total length of the outer perimeter of the substrate where the cable is installed is lower than a ratio of a total length of the plurality of projecting portions provided in a place where the cable is not installed with respect to a total length of the outer perimeter of the substrate where the cable is not installed.

US Pat. No. 10,653,389

ULTRASONIC DIAGNOSING DEVICE

Furuno Electric Co., Ltd....

1. An ultrasonic diagnosing device for diagnosing a state of a knee, based on echo signals caused by ultrasonic signals configured to be transmitted to the knee, comprising:a container body containing liquid;
an ultrasonic wave penetrable cover, covering an opening formed in the container body, and capable of, via elasticity, forming a curvature having a first portion in contact with a medial condyle side part of the knee and a second portion proximate and spaced apart from a right kneecap or a left kneecap of the knee;
a probe having an ultrasonic wave transmitter configured to transmit the ultrasonic signals, the probe immersed in the liquid inside the container body in a state where the ultrasonic wave transmitter is separated by a distance from the ultrasonic wave penetrable cover and opposes the ultrasonic wave penetrable cover, the ultrasonic signals configured to be transmitted to the knee through the liquid and the first portion of the ultrasonic wave penetrable cover by the ultrasonic wave transmitter; and
a drive motor configured to move the probe immersed in the liquid inside the container body, and further configured to change a position of the ultrasonic wave transmitter in a direction following a front surface shape of a cartilage of the knee,
wherein the container body has a housing formed to include a concavity and the ultrasonic wave penetrable cover is provided on a surface of the concavity that extends into a void of the concavity in a transmission direction of the ultrasonic signals further than a recessed adjacent surface of the concavity, so that the first portion of the ultrasonic wave penetrable cover is capable of contacting the medial condyle side part of the knee when the knee is received in the concavity of the housing, and so that the recessed adjacent surface accommodates another portion of the knee when the knee is received in the housing,
wherein the housing is formed with a right kneecap housing section in which the right kneecap is received when a right knee is received in the housing, and a left kneecap housing section in which the left kneecap is received when a left knee is received in the housing, the recessed adjacent surface forming a portion of one of the right kneecap housing section and the left kneecap housing section.

US Pat. No. 10,653,388

DEVICE AND METHOD FOR AUTOMATIC PNEUMOTHORAX DETECTION

KONINKLIJKE PHILIPS N.V.,...

1. An ultrasound system for scanning a lung of a subject comprising:a probe configured to obtain a sequence of temporal frames of ultrasound data relating to a scanning region including at least part of a pleural interface of the lung, each temporal frame of ultrasound data at least extending along a range direction of the probe; and
a data analyzer, comprising a processing circuitry, and configured to:
derive one or more than one correlation maps, each correlation maps being derived from a pair of temporal frames of the sequence of temporal frames;
filter the one or more than one correlation maps to obtain one or more than one filtered correlation maps;
derive one or more than one ultrasound data maps, each ultrasound map being derived from one temporal frame or a compounded version of more than one temporal frames of the sequence of temporal frames;
filter the one or more than one ultrasound data maps to obtain one or more than one filtered ultrasound data maps;
identify a first boundary line comprising a point from each line of a plurality of scanning lines, at which point a value change along the scanning line exceeds a first predetermined threshold in the one filtered correlation map or a compounded version of the more than one filtered correlation maps;
identify a starting point as a point at which there is a value increase along the first boundary line in the one filtered ultrasound data map or the compounded version of the more than one filtered ultrasound data maps, which value increase exceeds a second predetermined threshold;
identify an end point as a point at which there is a value decrease along the first boundary line in the one filtered ultrasound data map or the compounded version of the more than one filtered ultrasound data maps, which value decrease exceeds a third predetermined threshold.

US Pat. No. 10,653,387

METHOD AND DEVICE FOR FUNCTIONAL IMAGING OF THE BRAIN

CENTRE NATIONAL DE LA REC...

1. A method for functional imaging of the brain by ultrasonic waves, comprising the following steps:an atlas producing step during which a brain vascular atlas and a brain functional atlas are produced by
using at least one imaging technique to produce the brain vascular atlas of at least one subject from a certain class of subjects to be considered,
using a second type of imaging on the brain of the at least one subject giving a more accurate anatomic image of the brain than ultrasonic imaging to produce a reference anatomic atlas,
producing the brain functional atlas by matching the reference anatomic atlas with a functional anatomic atlas comprising a typical anatomic atlas having functional areas located on this typical anatomic atlas in order to locate the functional areas of the functional anatomic atlas on said brain vascular atlas,
a vascular imaging step during which a brain of a human or animal subject is imaged by ultrasonic imaging, in order to obtain a vascular image to be studied from which one or more of blood vessels and microvessels are viewable, said subject belonging to the certain class of subjects,
a localization step, during which, by shape recognition, at least one portion of the vascular image to be studied is automatically compared with at least one portion of the brain vascular atlas corresponding to said class of subjects, and the vascular image to be studied is thereby located in the brain vascular atlas,
an identification step during which the brain functional atlas corresponding to said brain vascular atlas and comprising the functional areas located in this brain vascular atlas is used, wherein a map of functional areas corresponding to said portion of the brain vascular atlas is determined, and the vascular image to be studied is superposed with said map of functional areas so that at least one brain functional area is identified on the vascular image to be studied.

US Pat. No. 10,653,386

MOBILE X-RAY MACHINE

Siemens Healthcare GMBH, ...

1. An apparatus for positioning an x-ray machine including an x-ray source and a detector, the apparatus comprising:a displaceable platform including a moveable x-ray source and/or detector, said platform displaceable by motorized, controllable wheels;
a computer supported on said platform, said computer including a controller configured to:
mark, in a first x-ray image in a 3D data record created preoperatively or intraoperatively, at least one alignment point or a trajectory in the 3D data record for forming at least one second x-ray image;
retrieve from the 3D data record, spatial coordinates of the noted alignment point or trajectory;
derive spatial coordinates for a position of the x-ray source for a second x-ray image from the received spatial coordinates of the alignment point or trajectory;
generate control signals to bring about motorized alignment of said x-ray source and/or detector, such that said alignment point or trajectory lies approximately centrally in a second x-ray image, said control signals controlling at least one of said motorized, controllable wheels or said moveable x-ray source and/or detector; and
said controller additionally configured to control the displacement of said platform supporting the x-ray source, the detector and said computer based on said alignment point or trajectory, by operating said motorized, controllable wheels to move said platform in order to position the x-ray machine.

US Pat. No. 10,653,385

TUBE ALIGNMENT FUNCTIONALITY FOR MOBILE RADIOGRAPHY SYSTEMS

KONINKLIJKE PHILIPS N.V.,...

1. An imaging system, comprising:an X-ray source;
an X-ray detector configured to receive X-rays from the X-ray source, at least one of the X-ray source and the X-ray detector being movable;
a radio frequency transmitter and a radio frequency receiver mounted to a common housing of the X-ray source and the X ray detector;
a plurality of reflectors, each reflector configured to resonate at a different radio frequency, wherein the radio frequency transmitter is configured to transmit a radio signal configured to cause the reflectors to resonate at different radio frequencies, and wherein the radio frequency receiver is configured to receive radio frequency resonant signals at each of the radio frequencies at which the reflectors are configured to resonate; and
a processor configured to:
receive the radio frequency resonant signals and convert the received radio frequency resonant signals into information indicative of a relative spatial configuration of the X-ray source and the X-ray detector,
determine positional correction information to guide relative motion of the X-ray source and the X-ray detector into alignment a predetermined distance from each other, and
control at least one of (1) an actuator to control the relative motion of the X-ray source and the X-ray detector, and (2) a prompter to issue at least one of optical, haptic, and acoustic signals to bring the X-ray source and the X-ray detector into the alignment at the predetermined distance.

US Pat. No. 10,653,384

METHOD FOR CALIBRATING AN X-RAY IMAGE

DENTSPLY SIRONA INC., Yo...

1. Method for calibrating at least one 2D X-ray image of an object to be imaged, which is recorded by means of an X-ray device in that X-rays produced by an X-ray source radiate through the object and are recorded by means of an X-ray detector, wherein an already existing 3D model comprising a first structure of the object is compared to the 2D X-ray image, wherein an actual image positional relationship of the X-ray source and the X-ray detector relative to the object, and/or relative to one another, is determined for the 2D X-ray image, wherein for the comparison of the 3D model with the 2D X-ray image and taking into account a predetermined image positional relationship, a virtual 2D projection image is produced by applying a virtual projection method to at least one part of the 3D model, wherein the first structure in the 2D x-ray image is compared to the first structure in the virtual 2D projection image, wherein deviations are identified during the comparison of the first structure in the 2D X-ray image with the virtual 2D projection image, wherein the image positional relationship is incrementally changed within the framework of an optimization method, and a new virtual 2D projection image is generated after each change until the deviations are smaller than a defined threshold value.

US Pat. No. 10,653,383

COMPUTED TOMOGRAPHY DEVICE AND METHOD FOR DETERMINING AN OPERATING STATE OF SLIDING CONTACTS IN A COMPUTED TOMOGRAPHY DEVICE

SIEMENS HEALTHCARE GMBJ, ...

1. A computed tomography device, comprising:a slipring for rotational transmission;
a feed line, the slipring being arranged to be rotatable relative to the feed line;
two sliding contact elements, forming two sliding contacts between a slideway of the slipring and the feed line, the two sliding contacts being connected in parallel with one another and electrically conductively connected together via at least one portion of the slideway and via at least one portion of the feed line;
a measuring apparatus, configured to acquire a measured value dependent on a resultant inductance between the two sliding contact elements; and
at least one processor, configured to determine an operating state of the two sliding contacts based upon the measured value.

US Pat. No. 10,653,382

IMAGE PROCESSING APPARATUS, RADIOGRAPHY SYSTEM, IMAGE PROCESSING METHOD, AND IMAGE PROCESSING PROGRAM

FUJIFILM CORPORATION, To...

1. An image processing apparatus comprising:an acquisition unit that acquires a first radiographic image generated by a first radiation detector irradiated with radiation with a first energy level and a second radiographic image generated by a second radiation detector irradiated with radiation with a second energy level different from the first energy level from a radiography apparatus including the first and second radiation detectors in which a plurality of pixels, each of which includes a conversion element that generates a larger amount of charge as it is irradiated with a larger amount of radiation, are arranged and which are arranged in a direction in which the radiation is emitted;
a derivation unit that derives at least one of bone mineral content or bone density from a derivation region of a difference image for derivation which is a difference image between the first radiographic image and the second radiographic image and is used to derive at least one of the bone density or the bone mineral content; and
a control unit that performs a control process of displaying a plurality of images that correspond to a single subject and that are predetermined from at least one of the first radiographic image or the second radiographic image, a bone part difference image which is a difference image between the first radiographic image and the second radiographic image and in which a bone tissue is highlighted, a soft part difference image which is a difference image between the first radiographic image and the second radiographic image and in which a soft tissue is highlighted, and the difference image for derivation on a display unit while switching the images and a control process of displaying at least one of a derivation result of the derivation unit or the derivation region on the display unit,
wherein the derivation unit is configured to derive the at least one of bone mineral content or bone density based on a difference image profile that indicates a relationship between a position of a pixel and a pixel value in the derivation region, by deriving an average value of pixel values in soft tissue regions on both sides of a bone tissue region, deriving an area of a bone region, dividing the area of the bone region by a number of pixels corresponding to a width of the bone region, and multiplying a difference between pixel values of the bone region and pixel values of the soft tissue region, per unit number of pixels, by a predetermined unit conversion coefficient.

US Pat. No. 10,653,381

MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE MOTION COMPENSATION IN BIOMEDICAL IMAGING

Kineticor, Inc., Honolul...

1. A biomedical system for tracking motion of an object during biomedical imaging and for compensating for motion of the object, the biomedical system comprising:a biomedical imaging scanner configured to perform scanning of the object to generate biomedical images of the object;
at least one detector for generating data describing at least a first landmark and a second landmark of the object,
one or more computer readable storage media configured to store a plurality of computer executable instructions; and
one or more hardware computer processors in communication with the one or more computer readable storage media and configured to execute the plurality of computer executable instructions in order to cause the biomedical system to:
determine motion of the first landmark using a first motion tracking technique;
determine motion of the second landmark using a second motion tracking technique;
differentiate between object movement and skin movement based at least in part on the determined motion of the first landmark and the determined motion of the second landmark;
generate motion tracking data of the object based at least in part on the object movement differentiated based at least in part on the determined motion of the first landmark and the determined motion of the second landmark; and
control one or more scanner parameters of the biomedical imaging scanner based on the generated motion tracking data, the scanner parameters configured for controlling the biomedical imaging scanner to account for motion of the object during the scanning of the object.

US Pat. No. 10,653,380

RADIOGRAPHIC SYSTEM AND RADIOGRAPHIC METHOD FOR OBTAINING A LONG-SIZE IMAGE AND CORRECTING A DEFECTIVE REGION IN THE LONG-SIZE IMAGE

Canon Kabushiki Kaisha, ...

1. A radiographic system, comprising:a plurality of radiation detection apparatuses which detect radial rays;
a memory storing a program; and
one or more processors which, by executing the program, function as:
a combining unit configured to generate a long-size image by combining a plurality of radiation images obtained by the plurality of radiation detection apparatuses;
an image correction unit configured to correct a defective region of the long-size image which is generated by the combining unit, wherein the image correction unit corrects the defective region using a pixel value of an image region other than the defective region, the defective region corresponding to a region of the long-size image in which the plurality of radiation detection apparatuses overlap with each other;
a gradation unit configured to perform a gradation process on the long-size image in which the defective region has been corrected by the image correction unit; and
a defective region obtaining unit which obtains, from a radiation image obtained from one of the plurality of radiation detection apparatuses, a defective region representing structure information of the other of the plurality of radiation detection apparatuses.

US Pat. No. 10,653,379

DEVICE AND METHOD FOR SPATIOTEMPORAL RECONSTRUCTION OF A MOVING VASCULAR PULSE WAVE IN THE BRAIN AND OTHER ORGANS

1. A system for extracting cardiac frequency angiographic phenomena from an angiographic study, the system comprising:a processor programmed to:
receive angiographic data from an angiographic study obtained at a rate faster than cardiac frequency;
apply a mathematical transform analysis that conserves time-indexing to the angiographic data to yield a spatiotemporal representation of cardiac frequency angiographic phenomena; and
generate images of the cardiac frequency angiographic phenomena from the spatiotemporal representation of the cardiac frequency angiographic phenomena.

US Pat. No. 10,653,378

IMAGE RETRIEVAL APPARATUS AND IMAGE RETRIEVAL METHOD

FUJITSU LIMITED, Kawasak...

1. An image retrieval apparatus that retrieves a candidate medical image in diagnosis of diffuse lung disease based on a position of an abnormal shadow in an organ region in a target medical image, the apparatus comprising:a memory; and
a processor coupled to the memory and configured to:
map the organ region in the target medical image to an image such that a contour of the organ region is changed to a geometric shape to make it identifiable whether the abnormal shadow is distributed over a first portion in the organ region or a second portion in the organ region, occurrence portions of the abnormal shadow within the first portion and the second portion are different; and
calculate a position of the abnormal shadow after the mapping in the image having the geometric shape,
wherein a first contour that is of a contour of the organ region and corresponds to the first portion is mapped to a first fixed contour that is part of a contour of the image having the geometric shape, and a second contour that corresponds to the second portion is mapped to a second fixed contour at a position opposed to the first contour, out of the contour of the image having the geometric shape,
wherein out of reduced contours obtained by reducing the contour of the organ region, a first reduced contour corresponding to the first portion is mapped to a first reduced fixed contour that is part of a reduced contour obtained by reducing the contour of the image having the geometric shape, and a second reduced contour corresponding to the second portion is mapped to a second reduced fixed contour at a position opposed to the first reduced fixed contour, out of the reduced contour obtained by reducing the contour of the image having the geometric shape,
wherein a region between nth reduced contour obtained by reducing the contour of the organ region by a first ratio, and (n+1)th reduced contour obtained by reducing the contour of the organ region by a second ratio higher than the first ratio is mapped to the image having the geometric shape so that a positional relationship between the nth reduced contour and the (n+1)th reduced contour is maintained.

US Pat. No. 10,653,377

BREAST COMPUTED TOMOGRAPHY SYSTEM COMPRISING A GRIPPER

Canon Kabushiki Kaisha, ...

1. A breast computed tomography system comprising:a light irradiation unit configured to irradiate a breast of an examinee with a light;
a scanning unit configured to change a relative position of the light emitting unit with respect to the breast;
a detection unit configured to detect waves extracted from a region of the breast irradiated with the light;
a gantry accommodating the light emitting unit and the detection unit, the gantry including a front plate configured to be adjacent to the examinee;
a breast insertion section communicating with an opening in the front plate; and
a gripper secured to the gantry,
wherein the gripper includes a right gripping portion and a left gripping portion.

US Pat. No. 10,653,376

X-RAY IMAGING SYSTEM

Sigray, Inc., Concord, C...

1. An x-ray imaging system comprising:an x-ray source configured to generate and emit x-rays in a periodic spatial pattern, the x-ray source comprising a substrate comprising a first material and a plurality of discrete structures on or embedded in the substrate, the plurality of discrete structures comprising a second material configured to generate the x-rays in response to electron irradiation, the plurality of discrete structures arranged in a two-dimensional pattern that is periodic in two directions;
a beam-splitting grating comprising a plurality of structures configured to diffract, for a predetermined x-ray wavelength, at least some of the x-rays impinging the beam splitting grating, the plurality of structures arranged in a two-dimensional array that is periodic in two directions;
a stage configured to hold an object to be imaged; and
an x-ray detector comprising a two-dimensional array of x-ray detecting elements, the x-ray detector positioned to detect x-rays diffracted by the beam-splitting grating and perturbed by the object to be imaged.

US Pat. No. 10,653,375

APPARATUS FOR DISPLAYING MEDICAL IMAGE DATA OF A BODY PART

KONINKLIJKE PHILIPS N.V.,...

1. An apparatus for processing medical image data of a body part, comprising:a processor configured to:
receive the medical data of the body part;
determine a plurality of subsets of medical image data;
calculate a plurality of measures of information content for the subsets of medical image data, wherein each measure of information content is associated with a corresponding subset of medical image data;
use the measures of information content to determine a plurality of weighting factors for the subsets of medical image data, wherein each weighting factor is associated with the corresponding subset of medical image data;
use the weighting factors to determine a plurality of durations of time for the subsets of medical image data, wherein each duration of time is associated with a corresponding subset of medical image data; and
a display configured to output the subsets of medical image data in direct proportion to the corresponding duration of time.

US Pat. No. 10,653,374

PORTABLE POSITRON EMISSION TOMOGRAPHY SCANNER HAVING A ROTATABLE DETECTOR RING WHICH CAN BE ROTATED 90 DEGREES FOR IMAGING A PATIENT IN A VERTICAL OR HORIZONTAL CONFIGURATION

Prescient Imaging, LLC, ...

1. A portable PET imaging scanner for vertically or horizontally imaging a region of interest of a patient within a scanning area, the PET imaging scanner comprising:a stable scan detector ring having an aperture, the detector ring having a detector depth of at least four inches and a diameter of at least nine inches for fully imaging a cross section of said region of interest of said patient;
at least four vertical lifting columns spaced apart from each other and attached to a portion of said scan detector ring for providing support and to stabilize image acquisition over the minutes required for said PET imaging scanner, where said scan detector ring is located on top ends of the at least four vertical lifting columns;
at least four motorized and synchronized devices each respectively connected to said at least four vertical lifting columns for providing vertical precise repeatability imaging so that multiple cross sections are aligned within a software;
two opposite rotating slew rings attached below said scan detector ring and having rotational rolling bearings for slow-turning said scan detector ring to rotate 90 degrees into unlock and lock in the vertical or horizontal configuration for imaging said patient in both the vertical and horizontal configurations, said stable scan detector ring in the vertical or horizontal configuration has significant height to create a depth of a field to wholly image most organs of interests of said patient within a cross-section of said patient of at least 15 centimeters in height for Cardiac under stress or breast and other cancer related imagery;
at least four wheel assemblies each respectively affixed to a bottom of said each vertical lifting column such that when the at least four wheel assemblies are deployed, said portable PET imaging scanner is moved from a first location to a second location and when the at least four wheel assemblies are retracted, said PET imaging scanner is secured and stationary to be used for imaging; and
an attachable control console for transporting said portable PET imaging scanner so that no ferrous components are in proximity of any imagery equipment when said scan detector ring is in the vertical or horizontal configuration, and for operator safely from radioactive emissions required for PET imaging scanner, said stable scan detector ring in either the vertical or horizontal configuration when stationary or in transport has a low center of gravity and subject to said patient movement and stress is not compromised and by providing leveling pads for patient scanning.

US Pat. No. 10,653,373

ACCOMMODATION APPARATUS OF RADIATION IMAGING APPARATUS, ACCOMMODATION SYSTEM AND RADIATION IMAGING SYSTEM

Canon Kabushiki Kaisha, ...

1. An accommodation apparatus that accommodates a radiation imaging apparatus in a cassette type, the radiation imaging apparatus having an external connection terminal for receiving electric power, the accommodation apparatus comprising:an accommodation unit including a bottom surface, a first wall surface adjacent to the bottom surface, a second wall surface adjacent to the bottom surface and provided at a position facing the first wall surface and a third wall surface adjacent to the bottom surface, the first wall surface and the second wall surface, the bottom surface, the first wall, the second wall, and the third wall being collectively arranged to be capable of accommodating the radiation imaging apparatus;
a power supply connector provided on the third wall surface, the power supply connector being connectable to the external connection terminal of the radiation imaging apparatus in a state in which the radiation imaging apparatus is accommodated in the accommodation unit; and
a coupling portion configured to couple with another accommodation apparatus, the coupling portion being (i) provided on a side surface that is positioned at opposite side of the first wall surface through the second wall surface and (ii) electrically connected to the power supply connector.

US Pat. No. 10,653,372

RADIATION IMAGING SYSTEM

CANON KABUSHIKI KAISHA, ...

1. A radiation imaging system including a pixel array having a plurality of pixels which are arranged to form a plurality of rows and a plurality of columns, a scanning circuit configured to scan the plurality of rows of the pixel array, and a readout circuit configured to read out signals from the pixel array, whereineach pixel includes a converter configured to generate an electric signal corresponding to radiation and a transistor connected to the converter, and the readout circuit is configured to read out a signal from the converter of each pixel via the transistor,
the radiation imaging system performs a plurality of image capturing modes of capturing a radiation image and a conditioning mode of conditioning a threshold voltage of the transistor of each pixel, and in the conditioning mode, the scanning circuit supplies, to a gate of the transistor, an OFF voltage different from OFF voltages in the plurality of image capturing modes, and
the scanning circuit scans the plurality of rows in units of at least one row in the plurality of image capturing modes, and scans the plurality of rows in units of at least two rows in the conditioning mode.

US Pat. No. 10,653,371

GRATED COLLIMATION SYSTEM FOR COMPUTED TOMOGRAPHY

University of Utah Resear...

1. A collimator for a computed x-ray tomography imaging device, comprising a first grating and a second grating positioned on opposing sides of a primary radiation delivery window, the first and second gratings being part of separate first and second leaves, each of the first and second gratings comprising a plurality of attenuating members with a plurality of secondary radiation delivery windows extending between adjacent attenuating members of the first grating and the second grating, respectively, and wherein a width of each attenuating member is proportional to a distance between the attenuating member and the primary window, and the first and second gratings are each adapted to receive x-rays from a single x-ray source.

US Pat. No. 10,653,370

SYSTEM WITH A GANTRY AND A RADIATION PROTECTION BOOTH AND METHOD FOR OPERATING A MEDICAL IMAGING APPARATUS

SIEMENS HEALTHCARE GMBH, ...

1. A system comprising:a gantry of a medical imaging apparatus, the gantry including an X-ray source;
a radiation protection booth having at least one wall surrounding a space into which a user may be enclosed, the radiation booth being installable or suspendable relative to the gantry; and
at least one of:
an intervention module for operating an intervention robot, wherein the intervention module is arrangeable in the radiation protection booth, and
an intervention robot.

US Pat. No. 10,653,369

DEVICE FOR HEALTH MONITORING AND RESPONSE

Intel Corporation, Santa...

1. An apparatus for health monitoring and response, comprising:a processor;
a plurality of sensors configured to collect data corresponding to a user of the apparatus; and
a health monitoring and response application, at least partially comprising hardware logic, wherein the health monitoring and response application is configured to:
test the data collected by any of the plurality of sensors to match the collected data with one or more predetermined health condition;
determine one or more current health condition of the user based at least in part on the one or more predetermined health condition that matches the collected data, wherein determining the one or more current health condition of the user includes determining that the user has fallen; and
automatically perform one or more action based at least in part on the determined one or more current health condition of the user, wherein the one or more action includes in response to determining that the user has fallen, controlling one or more locks.

US Pat. No. 10,653,368

DETERMINING WHEN TO EMIT AN ALARM

Cerner Innovation, Inc., ...

1. Non-transitory Computer-readable media having computer-executable instructions embodied thereon that when executed, facilitate a method of clinical decision-making, the method comprising:monitoring input from at least one medical device, wherein the input comprises a set of physiological measurements of a patient;
forming an estimate of a first variable, wherein the first variable is a dimension parameter over a first time interval based, at least in part, on a measure of roughness of a first plurality of the set of physiological measurements;
providing a first decision statistic based on the estimate of the first variable;
forming an estimate of a second variable, wherein the second variable is a second decision statistic over the first time interval based on the first plurality of the set of physiological measurements; and
generating an audio or visual notification in response to the first decision statistic crossing a breakpoint threshold and the second decision statistic crossing a physiological threshold over the first time interval, wherein the physiological threshold is based at least partially on the first plurality of physiological measurements.

US Pat. No. 10,653,367

HAPTIC FEEDBACK AND INTERFACE SYSTEMS FOR REPRODUCING INTERNAL BODY SOUNDS

Coleridge Design Associat...

1. A haptic system comprising:at least one acoustic sensor for receiving ballistic waves from a patient's body portion;
an amplifier for receiving electronic signals from the acoustic sensor and amplifying the received signals; and
a wearable device including at least one actuator,
wherein the at least one actuator of the wearable device is selectively energized based on the amplified received signal to impart to a wearer of the wearable device a haptic sensation of contact with the patient's body portion.

US Pat. No. 10,653,366

HAPTIC FEEDBACK DEVICE, SYSTEM AND METHOD

1. A haptic feedback system comprising:a sleep mask adapted to be worn about the head of a wearer having a left eye covering portion and a right eye covering portion and a band extending from both the left eye covering portion and the right eye covering portion and configured to laterally extend around the head of the wearer, wherein the band includes a device receiving portion that is located at a midpoint between the left eye covering portion and the right eye covering portion in the band such that the sleep mask is configured to position the device receiving portion on the back of the wearer's head when the wearer wears the sleep mask; and
a haptic feedback device that includes:
a circuit board;
a pressure sensor in operable communication with the circuit board;
a vibrator in operable communication with the circuit board, wherein the vibrator is configured to vibrate when the pressure sensor senses pressure above a threshold pressure;
a battery in operable communication with the circuit board;
wherein the circuit board, the vibrator, the pressure sensor and the battery are located in the device receiving portion of the band.

US Pat. No. 10,653,365

BIOLOGICAL INFORMATION PROCESSING DEVICE AND BIOLOGICAL INFORMATION PROCESSING METHOD

PANASONIC INTELLECTUAL PR...

6. A biological information processing method comprising:inputting image data capturing a plurality of processing targets;
extracting biological information data including pulse rates, from the plurality of the processing targets respectively captured in the input image data;
calculating a threshold based on the extracted biological information data from the plurality of processing targets;
detecting a target of the plurality of processing targets which is abnormal or requires special attention according to relative comparison between the calculated threshold and the extracted biological information data from the plurality of the processing targets;
outputting information with respect to the detected target;
storing a predetermined threshold used for a determination to specify the detected target which is abnormal or requires special attention; and
updating the predetermined threshold with the calculated threshold.

US Pat. No. 10,653,364

METHOD FOR THE CONTINUOUS EVALUATION OF THE VENTRICULO-AORTIC COUPLING OF AT-RISK PATIENTS BY ANALYSIS OF PRESSURE-FLOW LOOPS

1. A method for evaluating the ventricular-arterial coupling of a patient in real time on the basis of the aortic pressure/flow loop of said patient, comprising the following steps:(i) providing:
means for measuring arterial blood flow which comprises at least one of an esophageal Doppler device, a suprasternal Doppler device, a means for transthoracic cardiac echography, a means for transesophageal cardiac echography, and any combination thereof; and
means for measuring arterial pressure which comprises at least one of a catheter for measuring radial or femoral arterial pressure, a noninvasive tonometer, and any combination thereof;
(ii) measuring arterial blood flow with the means for measuring arterial blood flow;
(iii) measuring arterial pressure with the means for measuring arterial pressure;
(iv) determining, automatically by a computing device, on an aortic pressure/flow loop defined by the measured arterial blood flow and the measured arterial pressure, the coordinates of the following points:
A: point of the loop where the flow is zero and the pressure is at the minimum,
B: point of the loop where the flow is highest,
C: point of the loop where the pressure is highest, and
D: point of the loop where the flow is zero and the pressure is at the maximum;
(v) calculating, by the computing device, the percentage of the area (Stot) of the loop of part S2 located between straight lines (AB) and (AC) and/or angle ? between these two straight lines and/or acute angle ? between straight lines (AC) and (BD); and
(vi) interpreting, by the computing device, the results in the following way:
if S2/Stot?R2b and/or ??Gb and/or ??Db, the patient shows good ventricular-arterial coupling;
if S2/Stot?R2m and/or ??Gm and/or ??Dm, the patient shows poor ventricular-arterial coupling; and
in an intermediate situation, the quality of the ventricular-arterial coupling of the patient is intermediate,
R2b, R2m, Gb, Gm, Db, and Dm being predetermined thresholds.

US Pat. No. 10,653,363

TOPOLOGICAL EVOLUTION OF TUMOR IMAGERY

INTERNATIONAL BUSINESS MA...

1. A method comprising:reading a time series of medical images, each of the images depicting a subject anatomy and a lesion, the lesion having a size and a contour within each of the medical images;
reading at least one anatomical label for the subject anatomy within each of the plurality of images;
dividing each of the medical images into a plurality of disjoint regions; and
based upon the contour of the lesion within each of the medical images and based on the at least one anatomical label, predicting a further contour of the lesion outside of the time series, wherein
predicting the further contour comprises applying a hidden Markov model to the time series of medical images, and wherein
each of a plurality of hidden states of the hidden Markov model corresponds to whether the lesion is contained in a corresponding disjoint region of the plurality of disjoint regions.

US Pat. No. 10,653,362

MOTION AND NOISE ARTIFACT DETECTION AND RECONSTRUCTION ALGORITHMS FOR PHOTOPLETHYSMOGRAM AND EQUIVALENT SIGNALS

Wavefront Research Inc., ...

1. A computer implemented method for physiological parameter monitoring using a signal used as a Photoplethysmogram (PPG) signal, the computer implemented method comprising:obtaining a time frequency spectrum of a segment of the signal used as the PPG signal;
obtaining, from the time frequency spectrum, a noise quality index for the segment; the noise quality index being used to determine whether the segment is corrupted by motion and noise artifacts;
wherein obtaining a noise quality index comprises:
determining a dominant frequency in the time frequency spectrum of the segment;
normalizing the time frequency spectrum to a total power in a narrow band centered at the dominant frequency;
determining a first trace of amplitudes in the narrow band spectrum of the time frequency spectrum centered at the dominant frequency;
determining a second trace of amplitudes in a narrow band spectrum of the time frequency spectrum centered at twice the dominant frequency;
determining a third trace of amplitudes in a narrow band spectrum of the time frequency spectrum centered at three times the dominant frequency;
subtracting the first, second and third traces of amplitudes from the time frequency spectrum;
obtaining, after subtracting, a total power remaining in the time frequency spectrum, said total power remaining referred to as a residual noise power;
determining a difference in frequency between the first trace and the second and third traces, the difference in frequency referred to as a projected difference;
the noise quality index being a weighted sum of factors including the residual noise power and the projected difference; weights being selected such that each weighted factor represents less than a predetermined percentage of power in an uncorrupted segment;
applying a statistical learning method, using the noise quality index, to determine whether the segment is corrupted by motion and noise artifacts or not corrupted by motion and noise artifacts;
and,
if motion and noise artifacts are not present, including the segment in determination of a physiological parameter.

US Pat. No. 10,653,361

BREATH SENSORY ON A MOBILE COMMUNICATION DEVICE

Motorola Mobility LLC, C...

1. A method for performing breath analysis implemented by a mobile communication device, the method comprising:receiving, via an intake element of the mobile communication device, breath input from a user, the intake element being separate from an environment sensing inlet for receiving ambient air;
determining that the mobile communication device is operating in a call mode, and responsive to the mobile communication device operating in the call mode:
disabling the environment sensing inlet of the mobile communication device; and
enabling one or more sensors of the mobile communication device to sense one or more properties associated with the breath input;
analyzing the one or more properties associated with the breath input using a breath analysis module; and
providing a notification describing one or more results of the analyzing the one or more properties associated with the breath input.

US Pat. No. 10,653,360

SYSTEM AND METHOD OF DIRECTING BIOSIGNAL DETECTOR ARRANGEMENT

Daegu Gyeongbuk Institute...

1. A system for guaranteeing test-retest reliability by ensuring identical placement of a plurality of biosignal detectors in repeated re-arrangement of the plurality of biosignal detectors, the system comprising:a plurality of biosignal detectors configured to detect at least one biosignal of an object;
a measurer configured to obtain, in real-time, information including surface data of the object and position data associated with a placement arrangement of the plurality of biosignal detectors relative to the object, based on the surface data, said surface data describing a three dimensional (3D) structure of a certain surface of said object, wherein said placement arrangement describing a position of each of said plurality of biosignal detectors on said certain surface;
a processor configured to set a first information obtained from said measurer as reference information for a surface registration and compare the reference information to a second information obtained from said measurer; wherein said first information is associated with a first placement arrangement of said plurality of biosignal detectors on said surface of said object and wherein said second information is associated with a second placement arrangement of said plurality of biosignal detectors on said surface of said object, said second placement arrangement is a subsequent re-arrangement conducted following said first placement arrangement being an initial placement arrangement; and
a display configured to display the reference information and the second obtained information to guarantee test-retest reliability by ensuring identical placement arrangement by visualizing an overlap between said first placement arrangement and said second placement arrangement.

US Pat. No. 10,653,359

SYSTEM AND METHOD FOR PROVIDING WALKING PATH GUIDANCE SERVICE BASED ON MEASUREMENT OF MOTION OF USER

SK PLANET CO., LTD., Seo...

1. A method of providing a walking path guidance service, comprising:measuring a motion and position information of a user;
calculating a speed information using the measured motion and position information of the user;
creating a walking path from a starting point to a destination and calculating a time of arrival at the destination of the walking path according to the speed; and
calculating, when a movement according to the walking path is sensed, a moving speed using the motion and recommending a vehicle call service if a predetermined condition is satisfied.

US Pat. No. 10,653,358

METHOD AND SYSTEM FOR MONITORING INTOXICATION

KHN Solutions, Inc., San...

1. A method for informing a user of an intoxication state over time, comprising:a) at an electronics subsystem comprising a sensor coupled to a device borne on a wrist region of the user, receiving a sample from the user at a first time point;
b) at a processing subsystem in communication with the electronics subsystem, receiving a sample signal derived from the sample;
c) at the processing subsystem, determining a value of an intoxication metric from the sample signal;
d) continuously monitoring an intoxication state of the user by repeating a) to c) at a predetermined set of time points;
e) at the processing subsystem, determining a temporal profile of the intoxication metric for the user over time based on the values of the intoxication metric determined during d); and
f) at a user device in communication with the processing subsystem, displaying information derived from the temporal profile to the user.

US Pat. No. 10,653,357

DEVICE, METHOD AND SYSTEM FOR IMPLEMENTING A PHYSICAL AREA NETWORK FOR CANCER IMMUNOTHERAPY

1. A method of treating cancer comprising:positioning, in or on a user, a physical area network comprising:
a set of nano-nodes; and
at least one nano-micro interface,wherein at least one first nano-node in the set of nano-nodes includes a communication device to communicate with at least one second nano-node in the set of nano-nodes and/or the at least one nano-micro interface, further wherein at least one third nano-node in the set of nano-nodes comprises a cancer cell component derived from a cancer cell, wherein a surface of the at least one third nano-node in the set in nano-nodes is encapsulated with one or more plasma membrane-associated components, and wherein the one or more plasma membrane-associated components are derived from the cancer cell; andactivating an immune response against the cancer cell in the user, thereby treating the cancer.

US Pat. No. 10,653,356

TRAINING APPARATUS, TRAINING METHOD, AND PROGRAM

TOYOTA JIDOSHA KABUSHIKI ...

1. A training apparatus for rehabilitation, the apparatus comprising a processor configured to:simultaneously measure time-series myoelectric potentials of each of muscles 1, 2, . . . , m for a right side of a body of a subject while measuring the time-series myoelectric potentials for a left side of the body of the subject while the subject is performing different behaviors, the different behaviors being included in a task including bending and stretching a right wrist and a left wrist of the subject;
calculate a muscle synergy matrix W, a control matrix C and an error matrix E based on the acquired time-series myoelectric potentials and from a myoelectric potential matrix M so that a relationship M=WC+E is satisfied,
row vectors each expressing the acquired time-series myoelectric potentials of one of the muscles 1, 2, . . . , m being arranged in rows in the myoelectric potential matrix M, n unit column vectors W(1), W(2), . . . , W(n) being arranged in columns in the muscle synergy matrix W, and n row vectors C(1), C(2), . . . , C(n) being arranged in rows in the control matrix C;
calculate a right feature quantity for a muscle of the right side of the body of the subject and a left feature quantity for a muscle of the left side of the body of the subject, the muscle of the right side of the body and the muscle of the left side of the body being selected from the muscles 1, 2, . . . m;
compare the right feature quantity with the left feature quantity and determine a rehabilitation progress of the subject based on the comparison, the comparison indicating consistency among the unit column vectors W(1), W(2), . . . , W(n) included in the calculated muscle synergy matrix W; and
provide the subject with feedback of progress of training based on the comparison between the right feature quantity and the left feature quantity, the feedback of progress being used to efficiently assess the rehabilitation progress, wherein providing the subject with the feedback of progress of training includes applying electrical stimulation to a portion of the body of the subject.

US Pat. No. 10,653,355

NON-INVASIVE VISUALIZATION AND QUANTIFICATION OF NATURAL PIGMENTS

THE GENERAL HOSPITAL CORP...

1. A system comprising:an imaging system to record a signal based on a presence of melanin in tissue comprising:
a first laser source to emit a Stokes pulse train comprising a first center wavelength or frequency;
a second laser source to emit a pump pulse train comprising a second center wavelength or frequency,
wherein an energy difference between the Stokes pulse train and the pump pulse train is from 1750 cm?1 to 2250 cm?1,
wherein the Stokes pulse train and the pump pulse train overlap in space and time to image the tissue;
a scanning mechanism to focus a combination of the Strokes pulse train and pump pulse train within the tissue and scan across the tissue;
a detector to detect the signal based on a presence of melanin within the tissue, wherein the signal comprises a coherent anti-Stokes Raman scattering (CARS) signal and a modulation transfer signal; and
a display device to display an image based on the signal to visualize the melanin present in the tissue.

US Pat. No. 10,653,354

MEDICAL TESTING APPARATUS AND METHOD OF USE

Ohio State Innovation Fou...

1. A medical testing apparatus for penetrating a patient's tissue with an agent, the apparatus comprising:an arcuate rail having spaced first and second sides supported by upper and lower arcuate surfaces;
an arcuate handle having first and second ends extending from said upper surface of said arcuate rail; and
a plurality of tips extending substantially from and normally away from the lower arcuate surface, the plurality of tips comprising alternating blunt tips and reed tips, wherein a selectively removable and replaceable strip supports said plurality of reed tips, said selectively removable and replaceable strip removably coupled to said lower arcuate surface by an adhesive, said plurality of tips being supported by the surface of said removable strip.

US Pat. No. 10,653,353

MONITORING A PERSON FOR INDICATIONS OF A BRAIN INJURY

INTERNATIONAL BUSINESS MA...

1. A method for monitoring a user of a uniform for a traumatic brain injury, the method comprising:monitoring an acceleration of a head of a user with a plurality of sensors embedded in the uniform, wherein the uniform comprises a helmet and an outfit worn by the user;
wherein the plurality of sensors comprise a gyroscope and an accelerometer;
wherein the gyroscope is embedded in the helmet;
wherein the accelerometer is embedded in the outfit;
selectively activating the gyroscope to monitor one or more characteristics of a gait of the user based on the acceleration exceeding a threshold level;
measuring, by the accelerometer a stride of the user;
determining that the one or more characteristics of the gait and the measured stride of the user indicate that the user may have suffered the traumatic brain injury, wherein the one or more characteristics of the gait of the user comprises a duty factor and a forelimb-hindlimb phase relationship; and
wherein the determination that the one or more characteristics of the gait indicate that the user may have suffered the traumatic brain injury is based on a comparison of the one or more characteristics of the gait of the user to a baseline reading of the one or more characteristics of the gait and a baseline measurement of the stride of the user;
creating an alert that the user of the helmet may have suffered the traumatic brain injury.

US Pat. No. 10,653,352

FEEDBACK DEVICE FOR IMPROVED BALANCE CONTROL

RxFunction, Inc., Eden P...

1. A system for assisting the maintenance of balance of a user, the system comprising:a) at least one sensor positionable against or adjacent to a body part of the user, wherein the at least one sensor is configured to generate, during user stance and dynamic activities, user balance information signals and transmit the user balance information signals;
b) a signal processing subsystem, the subsystem configured to receive the user balance information signals, and generate, based on the user balance information signals, balance control signals reflecting user balance information; and
c) at least one stimulator configured to be positionable against or adjacent to a skin area of the user, the at least one stimulator configured to be responsive to the balance control signals to provide skin stimulation during the user stance and dynamic activities to the skin area of the user, thereby providing feedback to the user.

US Pat. No. 10,653,351

SYSTEMS AND METHODS FOR QUANTIFICATION OF POSTURAL BALANCE OF USERS IN AN AUGMENTED REALITY ENVIRONMENT

Tata Consultancy Services...

1. A method for quantifying postural balance of users in an augmented reality (AR) environment, the method comprising a processor implemented steps of:acquiring, by a sensor, a first set of information from one or more users, wherein the first set of information comprises a set of data on skeleton joints of the one or more users performing various functional tasks in the AR environment;
filtering, using a multivariate de-noising technique, the first set of information for extracting a filtered set of data to compute a set of postural data of the one or more users, wherein the filtered set of data comprises data obtained by filtering noise from the first set of information;
computing, based upon the filtered set of data, the set of postural data for quantifying the postural balance of the one or more users, wherein the set of postural data comprises data on postures and activities of the one or more users, and wherein the computation of the set of postural data comprises augmenting Single Leg Stance (SLS) functional tasks with variations in step heights of the one or more users for computing SLS time duration, vibration of hip joints and center of mass sway area, and wherein the augmented SLS functional tasks with variations in step height are classified into various pre-defined activity levels based on the one or more users physical ability or difficulty level; and
quantifying, using a fuzzy controller in the AR environment, the postural balance of the one or more users based upon the set of postural data by:
computing a plurality of postural stability index scores, by performing a correlation of the set of postural data with one or more threshold values based upon a set of fuzzy rules, wherein the one or more threshold values comprises a set of pre-defined stability values obtained by performing a classification each of the SLS time duration, the vibration of hip joints and the center of mass sway area under different categories, and wherein the plurality of postural stability scores are computed for the SLS functional tasks of each pre-defined activity level in order to determine variations in postural balance due to changes in activity level; and
providing, real-time feedback in the AR environment for correcting the posture of the one or more users by interpreting the one or more postural stability index scores computed.

US Pat. No. 10,653,350

DATA PROCESSING DEVICE, MONITORING SYSTEM, AWAKENING SYSTEM, DATA PROCESSING METHOD, AND DATA PROCESSING PROGRAM

OMRON Corporation, Kyoto...

1. A data processing device that performs data processing of monitoring a person, the data processing device comprising a processor configured with a program to perform operations comprising:operation as a calculator configured to calculate pupil movement and head movement of the person;
operation as an evaluator configured to evaluate a suitability degree of a situation in calculating vestibulo-ocular reflex movement based on the pupil movement and the head movement of the person;
operation as a provision unit configured to provide the suitability degree evaluated by the evaluator to data relating to the pupil movement and the head movement of the person calculated by the calculator;
operation as a selector configured to select a first technique of calculating sleepiness based on the vestibulo-ocular reflex movement of the person or a second technique different from the first technique based on the suitability degree provided to the data;
operation as a first sleepiness calculator configured to calculate the sleepiness based on the first technique when the selector selects the first technique; and
operation as a second sleepiness calculator configured to calculate the sleepiness based on the second technique when the selector selects the second technique.

US Pat. No. 10,653,349

DIAGNOSTIC APPARATUS

International Business Ma...

1. A diagnostic patch apparatus comprising:a sampling module comprising:
sampling means for sampling fluid from a patient's skin when the sampling module is placed against the skin;
a sample chamber coupled in fluid communication with the sampling means;
at least one diluent chamber containing an analytic diluent and coupled in fluid communication with the sample chamber via a diluent valve; and
at least one reagent chamber containing an anticoagulant reagent and coupled in fluid communication with the sample chamber via a reagent valve; and an analysis module comprising:
a fluid conduit coupled in fluid communication with the sample chamber of the sampling module; and
a plurality of sensors coupled in fluid communication with the fluid conduit.

US Pat. No. 10,653,348

FOOT PULSE OXIMETER FOR SCREENING CONGENITAL HEART DISEASE BEFORE NEWBORN DISCHARGE

LOS ANGELES BIOMEDICAL RE...

1. A method comprising:placing a portion of a foot of a newborn in a device, the device comprising;
a light emitter and a corresponding receiver coupled on opposite sides of the device,
a processor for processing data from the light emitter and receiver;
a chamber configured to receive the portion of the foot of the newborn, and
a cover configured to be inserted into the chamber and form a double layer structure with the chamber, the cover configured to cover the portion of the foot of the newborn when the portion of the foot of the newborn is in the chamber,
wherein placing the portion of the newborn's foot in the device comprises placing the cover into the chamber, and placing the portion of the newborn's foot into the cover, such that the cover covers the portion of the newborn's foot within the chamber, and
wherein the cover comprises translucent areas and non-translucent areas, locations of the translucent areas positioned to correspond to positions of the light emitter and the receiver, and
determining a presence of congenital heart disease in the newborn based on the data from the light emitter and receiver.

US Pat. No. 10,653,347

NON-INVASIVE MEASUREMENT DEVICE AND METHOD FOR ESTIMATING LOCAL METABOLIC PARAMETERS

APD ADVANCED PERFUSION DI...

1. A method for estimation of at least one local metabolic parameter of a relevant tissue area of a patient, wherein the method comprises the following steps:shifting a catheter over a surface of the relevant tissue area, an optical sensor of an acquisition device being disposed at a distal end of the catheter,
wherein said optical sensor is comprised of at least three diodes and a receiver, each diode emitting a light radiation at a defined wavelength different of the others diodes so that the optical sensor emits a light intensity for at least three different wavelengths comprised between 600 and 1000 nm, the at least three different wavelengths being selected as a function of absorptivity of oxyhemoglobin and deoxyhemoglobin, said receiver measuring light intensity for the at least three different wavelengths,
positioning said optical sensor, against the wall of the relevant tissue area,
emitting each light radiation by each diode of the optical sensor at each of the at least three different wavelengths,
receiving said light intensity having passed through the relevant tissue area, said light intensity being measured by the receiver for at the least three different wavelengths so as to determine received light intensities,
wherein the step of receiving said light intensity comprises a step of: receiving, a plurality of measured light intensities at different instants of a cardiac cycle for each of the at least three different wavelengths,
generating curves of said received light intensities over several cardiac cycles,
selecting at least one instant of the cardiac cycle of each plurality of measured light intensities so as to determine each selected light intensity for each wavelength,
calculating absorbance values from each selected light intensity for the at least three different three wavelengths,
determining a concentration of oxyhemoglobin and a concentration of deoxyhemoglobin from the absorbance values calculated for the at least three different three wavelengths, and
estimating at least one local metabolic parameter of the relevant tissue area of the patient from said concentrations of oxyhemoglobin and said concentration of deoxyhemoglobin,
wherein the step of estimating comprises: estimating oxygen consumption in the relevant tissue area from said concentrations of oxyhemoglobin and said concentration of deoxyhemoglobin in the total blood and in the venous blood,
wherein the step of selecting comprises: detecting at least one of a maxima and a minima in the curves of said received light intensities at the at least three wavelengths,
wherein, from all the measured light intensities of each wavelength, a light intensity for which an amount of arterial blood is minimum in the relevant tissue area such that the determined concentrations are representative of concentration of oxyhemoglobin and deoxyhemoglobin in the venous blood, and
wherein, from all the measured light intensities, light intensities for which the amount of arterial blood is maximum in the relevant tissue area such that the determined concentrations are representative of concentration of oxyhemoglobin and deoxyhemoglobin in the total blood.

US Pat. No. 10,653,346

HAND-HELD OPTICAL SCANNER FOR REAL-TIME IMAGING OF BODY COMPOSITION AND METABOLISM

The Regents of the Univer...

1. An apparatus for combining continuous wave and frequency domain diffuse optical spectroscopic imaging (CWFD DOSI) comprising:a frequency domain photon migration (FDPM) module;
a continuous wave diffuse optical spectroscopic (CW) module; and
a controller coupled to the FDPM and CW module to control the FDPM module and CW module in a multimode operation which comprises an accuracy derived from a direct measurement of optical scattering from the FDPM module at a speed obtained from the CW module,
wherein the source of the CW module comprises:
a laser driver;
an oscillator configured to modulate the laser driver at a frequency of less than 19 KHz to suppress background noise from ambient light on a source and a detector of the CW module; and
a narrow bandpass filter coupled to the laser driver, and
wherein the detector of the CW module comprises a plurality of narrowband transimpedance amplifiers with active filters disposed after a photodiode configured to detect light from a tissue.

US Pat. No. 10,653,345

BLOOD PROCESSING APPARATUS COMPRISING A HOLDER DEVICE FOR A MEASUREMENT DEVICE

Fresenius Kabi Deutschlan...

1. A blood processing apparatus, comprising:a measurement device having at least one chamber element for receiving a blood fluid, wherein the at least one chamber element extends along a longitudinal axis and comprises a circumferential wall extending about the longitudinal axis, a bottom wall and a top wall together defining a flow chamber, the at last one chamber element further comprising an inlet port for allowing a flow of a blood fluid into the flow chamber and an outlet port for allowing a flow of a blood fluid out of the flow chamber,
a holder device for holding the measurement device, the holder device comprising a base having a reception opening for receiving the measurement device and a closure element movably arranged on the base for locking the measurement device in an inserted position in the reception opening, and
an ultrasonic sensor of the holder device arranged on the base,
wherein the ultrasonic sensor, in the inserted position of the measurement device, is directed along the longitudinal axis of the at least one chamber element and faces the bottom wall of the at least one chamber element to transmit an ultrasonic signal into the flow chamber through the bottom wall, wherein the bottom wall extends transversely with respect to the longitudinal axis.

US Pat. No. 10,653,344

METHOD AND APPARATUS FOR PROVIDING DATA PROCESSING AND CONTROL IN A MEDICAL COMMUNICATION SYSTEM

Abbott Diabetes Care Inc....

1. A method of determining analyte information, comprising:receiving, at a receiving device, a current signal associated with a monitored analyte level from an in vivo analyte sensor by a communication protocol;
retrieving stored signals associated with the monitored analyte level;
determining that more than a predetermined number of a combination of the retrieved stored signals and the current signal are corrupt; and
in response to determining that more than the predetermined number of the combination of the retrieved stored signals and the current signal are corrupt, temporarily disabling an alarm from being output by the receiving device.

US Pat. No. 10,653,343

SYSTEM AND METHOD FOR NON-INVASIVE GLUCOSE MONITORING USING NEAR INFRARED SPECTROSCOPY

New Jersey Institute of T...

1. A method of monitoring blood concentration of a substance comprising:illuminating a specified location of a subject a first time with one or more light sources using near infrared spectroscopy, wherein a wavelength of the one or more light sources is in the range of 600 nm to 1,000 nm;
detecting, via one or more linear source-detector array sensors aligned with the one or more light sources, initial absorption data and pulse oximetry information in response to illumination of the specified location the first time;
sampling the initial absorption data, via one or more processors, at a first sampling rate, wherein the initial absorption data relates to one or more absorption coefficients, and wherein the initial absorption data is sampled over a heart cycle event;
illuminating the specified location of the subject a second time with the one or more light sources using near infrared spectroscopy in the range of 600 nm to 1,000 nm;
detecting a second set of absorption data in response to illumination of the specified location the second time;
sampling the second set of absorption data, at a second sampling rate, via the one or more processors, wherein the second sampling rate is lower than the first sampling rate, and wherein the second set of absorption data relates to the one or more absorption coefficients;
adjusting, via the one or more processors, at least the second set of absorption data based on a convolution function, wherein the adjusted second set of absorption data comprises at least a melanin skin absorption coefficient, a blood skin absorption coefficient, and a baseline skin absorption coefficient; and
estimating a level of the substance in the blood based at least in part on:
the pulse oximetry information, and a mixing model equation, wherein the mixing model equation is based at least in part on a sum of:
a product of the melanin skin absorption coefficient and a melanin concentration associated with the melanin skin absorption coefficient,
a product of the blood skin absorption coefficient and a blood concentration associated with the blood skin absorption coefficient, and
a product of the baseline skin absorption coefficient and a baseline skin concentration, wherein:
the baseline skin concentration is a difference between one and the sum of the melanin concentration and the blood concentration, and
the baseline skin absorption coefficient is based at least in part on a natural exponential function of the wavelength; and
a genetic algorithm chromosome associated with a concentration of the substance in a tissue beneath the specified location, that is utilized to obtain a final reading for the estimate.

US Pat. No. 10,653,342

SOFT, WEARABLE MICROFLUIDIC SYSTEMS CAPABLE OF CAPTURE, STORAGE, AND SENSING OF BIOFLUIDS

The Board of Trustees of ...

66. A method of analyzing a biofluid; said method comprising:providing a device for handling a biofluid; said device comprising:
a soft and flexible functional substrate for adhering and conforming to a surface of the skin, said functional substrate comprising a microfluidic network channel having a plurality of microchannels, reservoirs and passive burst valves configured for time-dependent collection of said biofluid; and
a plurality of sensors supported by said functional substrate and configured for multiparametric analysis of said biofluid;
wherein said functional substrate provides for microfluidic transport of at least a portion of said biofluid to said sensors; and wherein said plurality of sensors include at least a first sensor configured for determining a first concentration of an analyte over a first concentration range and a second sensor configured for determining a second concentration of said analyte or a different analyte over a second concentration range different from said first concentration range to provide multiparametric and chrono-sampling of said biofluid;
conformally contacting said functional substrate of said device with a surface of the skin of a subject; and
temporally analyzing said biofluid from said surface of the skin of said subject.

US Pat. No. 10,653,341

AUDITORY STIMULUS FOR AUDITORY REHABILITATION

1. A method performed by one or more processing devices, the method comprising:intermittently determining whether a location of a visual representation of an object in a graphical user interface displayed during execution of a program corresponds to a location of a virtual target in the graphical user interface until the location of the visual representation of the object in the graphical user interface corresponds to the location of the virtual target;
while the location of the visual representation of the object in the graphical user interface does not correspond to the location of the virtual target,
determining a proximity of the visual representation of the object to the virtual target in the graphical user interface;
modifying, based on the proximity, an auditory stimulus signal indicative of the location of the virtual target in the graphical user interface by modifying a frequency of the auditory stimulus signal, a signal-to-noise ratio of the auditory stimulus signal, a sound level of the auditory stimulus signal, a binaural characteristic of the auditory stimulus signal, or a modulation of a sound envelope of the auditory stimulus signal; and
causing one or more speaker devices to play the modified auditory stimulus signal;
following the location of the visual representation of the object in the graphical user interface corresponding to the location of the virtual target,
causing completion of the program.

US Pat. No. 10,653,340

WEARABLE PHYSIOLOGY MONITOR COMPUTER APPARATUS, SYSTEMS, AND RELATED METHODS

Vision Service Plan, Ran...

1. A computerized eyewear comprising:at least one processor;
one or more sensors operatively coupled to the at least one processor;
a power source operatively coupled to the at least one processor; and
a communication device operatively coupled to the at least one processor,
wherein the computerized eyewear is configured to:
at least partially in response to receiving at least one signal at a first time or a first period of time from the one or more sensors, determine a normal physiology of the wearer of the computerized eyewear;
at least partially in response to receiving at least one signal at a second time or a second period of time, determine a current physiology of the wearer of the computerized eyewear;
at least partially in response to determining the current physiology of the wearer, compare the current physiology of the wearer to the normal physiology of the wearer; and
notify the wearer when the current physiology of the wearer deviates from the normal physiology of the wearer.

US Pat. No. 10,653,339

TIME AND FREQUENCY DOMAIN BASED ACTIVITY TRACKING SYSTEM

NXP B.V., San Jose, CA (...

1. A system for activity tracking, the system comprising:a 3-dimensional (3-D) accelerometer configured to sense activity in each of three orthogonal axes being X-axis, Y-axis and Z-axis, and generating accelerometer data associated with the three axes;
a pre-processor coupled to the 3-D accelerometer and including a filter circuit configured and arranged to remove noise from the accelerometer data and, therefrom produce filtered data including vertical and horizontal component data and accelerometer data associated with each of the three axes; and
a computer processor configured and arranged with previously-obtained statistical data indicative of a plurality of attributes of each different activity classes characterizing movement of a user and with programming instructions which when executed, the computer processor performs operations to identify, independent of orientation of the 3-D accelerometer, one of the different activity classes corresponding to produced accelerometer data, the operations including the following:
deriving, from the filtered data, values associated with activity-indicative attributes including mean value, time domain energy of filtered data, and variance of the vertical and horizontal component data,
processing and comparing each of the values of the activity-indicative attributes with the previously-obtained statistical data to classify the produced accelerometer data as corresponding to a selected current activity from among the different activity classes, and
tracking and characterizing the tracked data as the selected current activity of one of the different activity classes, wherein the selected current activity corresponds with the movement of the user.

US Pat. No. 10,653,338

SENSING DEVICE

Thomas J. Cunningham, Sm...

1. A system for analyzing a movement of a body, the system comprising:a covering for a body, the covering including:
a first covering portion configured to cover a moving segment of the body;
a second covering portion configured to cover a reference segment of the body;
wherein:
one of the first and second covering portions includes a triggering mechanism;
the other of the first and second covering portions includes a sensor operatively connected to the triggering mechanism such that a movement of the moving segment activates the triggering mechanism to provide an input to the sensor; and
wherein the input activates the sensor to generate an output defined by the movement;
an intermediate mechanism interposed between the triggering mechanism and the sensor;
wherein the intermediate mechanism is configured to isolate the input from the sensor when the input does not meet a predetermined threshold.

US Pat. No. 10,653,337

LOCAL OBJECT DETECTION SYSTEM

7. A computer readable memory comprises:a first memory element that stores operational instructions that, when executed by a transmitter section of a local object detection system, causes the transmitter section to:
transmit one or more local transmit radar signals;
a second memory element that stores operational instructions that, when executed by a plurality of receivers of the local object detection system, cause the plurality of receivers to:
receive a plurality of local receive radar signals that corresponds to the one or more local transmit radar signals being reflected or refracted off an object; and
receive a second plurality of local receive radar signals that corresponds to the one or more local transmit radar signals being reflected or refracted off a second object;
a third memory element that stores operational instructions that, when executed by a processing module of the local object detection system, causes the processing module to:
process the plurality of local receive radar signals to determine a relative position of the object;
determining whether the object is positioned within a desired detection volume associated with a position of the transmitter section;
when the object is positioned within the desired detection volume, further process the plurality of local receive radar signals to determine movement pattern of the object;
determine whether the movement pattern of the object is within a range of plausible movements for the object;
when the movement pattern of the object is within a range of plausible movements for the object, track movement of the object within the desired detection volume;
process the second plurality of local receive radar signals to determine a second relative position of the second object;
determine whether the second object is positioned within the desired detection volume;
when the second object is positioned within the desired detection volume, further process the second plurality of local receive radar signals to determine second movement pattern of the second object;
determine whether the second movement pattern of the second object is within a second range of plausible movements for the second object; and
when the second movement pattern of the second object is within the second range of plausible movements for the second object, track movement of the second object within the desired detection volume;
when the first object is a baseball and the second object is a bat, determine a contact point of the bat colliding with the baseball based on the movements and positions of the baseball and the bat within the desired detection volume.

US Pat. No. 10,653,336

SUBCUTANEOUSLY IMPLANTABLE SENSOR DEVICES AND ASSOCIATED SYSTEMS AND METHODS

Intel Corporation, Santa...

1. An apparatus, comprising:a substrate comprising a corrosion-free metal or polymeric material;
at least one sensor disposed on a surface of the substrate to detect or measure one or more analytes in a human body, wherein the at least one sensor comprises an electrochemical sensor;
a communication circuitry disposed inside the substrate and coupled with the at least one sensor, to wirelessly communicate data that corresponds to the detection or measurements of the one or more analytes to a remote device;
a controller circuitry disposed inside the substrate and coupled with the at least one sensor and the communication circuitry, to control operation of the at least one sensor and the communication circuitry, including collection of data associated with the detection or measurements of the one or more analytes, and transmission of the collected data to the remote device; and
a power source disposed inside the substrate, to power the apparatus,
wherein the apparatus is implantable in the human body.

US Pat. No. 10,653,335

MAGNETIC RESONANCE IMAGING DEVICE AND RF COIL ASSEMBLY WITH MATCHING SWITCH CIRCUIT AND TUNING SWITCH CIRCUIT

Hitachi, Ltd., Tokyo (JP...

1. A magnetic resonance imaging device, comprising:a gantry that is provided with a static magnetic field generator that generates a static magnetic field and a gradient magnetic field generation coil that generates a gradient magnetic field;
a table that is disposed in the gantry and on which a test object is placed;
an RF coil that is configured so that a part thereof is fixed to the gantry or the table and at least another part thereof is formed of a flexible material and is deformable to be in contact with the test object, and receives a nuclear magnetic resonance signal generated from the test object;
a fixture that fixes the RF coil to the test object; and
a detector that detects the shape of the RF coil,
wherein the RF coil includes a matching switch circuit and a tuning switch circuit configured to change a matching constant and a tuning constant of the RF coil according to an output of the detector and configured to be in an optimal matching state and an optimal tuned state when the test object is placed on the RF coil in a state where the RF coil is flatly mounted on the table,
wherein the detector includes an RF coil-side connector disposed ancillary to the RF coil, a fixture-side connector disposed ancillary to the fixture, and a mechanism switch that turns on or off a connection between terminals when the RF coil-side connector and the fixture-side connector are connected to each other, and
wherein the matching switch circuit and the tuning switch circuit have a circuit configuration that varies according to whether the mechanism switch turns the connection on or off, and respectively switch the matching switch circuit and the tuning switch circuit into the optimal matching state and the optimal tuned state in a shape of the RF coil corresponding to each of on the on state and the off state of the mechanism switch.

US Pat. No. 10,653,334

IMPEDANCE MEASUREMENT SYSTEM

1. A system for performing at least one impedance measurement on a biological subject, the system including:a) a measuring device having:
i) a first housing including spaced pairs of foot drive and sense electrodes adapted to be placed in electrical contact with feet of the subject in use, wherein the first housing includes a raised lip extending at least partially around each pair of foot drive and sense electrodes to thereby guide positioning of a subject's foot relative to the foot drive and sense electrodes in use;
ii) a second housing including:
spaced pairs of hand drive and sense electrodes, each pair of hand drive and sense electrodes being adapted to be placed in electrical contact with a respective hands of the subject in use, wherein the second housing has a curved upper surface and is shaped to at least partially conform to a shape of a subject's hands so that each of a subject's hands can rest on a respective pair of electrodes with one of the hand drive and sense electrodes in contact with the subject's fingers and another one of the hand drive and sense electrodes in contact with the subject's palm;
a raised portion between each pair of hand drive and sense electrodes, and the raised portion includes two ridges, each ridge extending towards a respective pair of hand and sense electrodes, and being adapted to be positioned between a subject's thumb and forefinger to thereby guide positioning of the subject's hand relative to the hand drive and sense electrodes in use;
iii) at least one signal generator electrically connected to at least one of the drive electrodes to apply a drive signal to the subject;
iv) at least one sensor electrically connected to at least one of the sense electrodes to measure a response signal in the subject; and,
v) a measuring device processor that at least in part:
(1) controls the at least one signal generator;
(2) receives an indication of a measured response signal from the at least one sensor; and,
(3) generates measurement data indicative of at least one measured impedance value; and,
b) a client device in communication with the measuring device, the client device comprising a processor and display, the client device being adapted to receive measurement data from the measuring device, allowing the client device to display an indicator associated with a result of the impedance measurement.

US Pat. No. 10,653,333

SYSTEMS AND METHODS FOR HIGH FREQUENCY IMPEDANCE SPECTROSCOPY DETECTION OF DAILY CHANGES OF DIELECTRIC PROPERTIES OF THE HUMAN BODY TO MEASURE BODY COMPOSITION AND HYDRATION STATUS

Ori Diagnostic Instrument...

1. A method comprising:generating, at a first excitation circuit, a set of electrical parameters for a first foot of a human body;
generating, at a second excitation circuit, the set of electrical parameters for a second foot of the human body;
sensing a voltage measurement of the first foot and the second foot;
collecting, via an input channel of a controller unit comprising circuitry and memory, the voltage measurement and the set of electrical parameters for the first foot and the second foot to create a digitized voltage signal;
controlling a measuring sequence of the human body, via an output channel of the controller unit, by utilization of the digitized voltage signal;
processing the measure sequence, via a processor unit, to obtain a plurality of metabolic parameters for the human body;
performing a series of mathematical calculations based on the measure sequence and the plurality of metabolic parameters for the human body to determine measurement errors; and
in response to determining the measurement errors, calculating a resistance of the human body at an estimated zero frequency and an extrapolated infinite frequency,
wherein processing the measure sequence comprises:
running a sine wave fit algorithm to determine an offset, an amplitude, and a phase of the digitized voltage signal;
processing a part one stage one measurement to determine an admittance of a plurality of excitation electrodes, an admittance of a plurality of sensing electrodes, an admittance of segment impedances interspaced between the plurality of excitation electrodes and the plurality of sensing electrodes, and an admittance of current losses through the first foot and the second foot;
processing a part one stage two measurement to determine a stray capacitance of a measured segment of the human body;
processing a part one stage three measurement to determine complex impedances at multiple frequencies of the measured segment of the human body;
processing a part two stage one measurement to perform a Cole model curve fitting to the complex impedances at multiple frequencies of the measured segment of the human body;
processing a part two stage two measurement to perform a statistical test goodness fit of a chosen model for the complex impedances at multiple frequencies of the measured segment of the human body in order to obtain a best fit model;
processing a part three stage one measurement to determine a quasi-stable ratio of an extracellular water mass to a total body water mass;
processing a part three stage two measurement to determine the extracellular water mass and an intracellular water mass; and
processing a part three stage three measurement to determine a lean body mass, a fat mass, and a protein mass.

US Pat. No. 10,653,332

CONDUCTIVE STIFFENER, METHOD OF MAKING A CONDUCTIVE STIFFENER, AND CONDUCTIVE ADHESIVE AND ENCAPSULATION LAYERS

MC10, Inc., Lexington, M...

1. A device comprising:a flexible printed circuit board having a plurality of discrete operative devices electrically interconnected and one or more contact pads on a backside of the flexible printed circuit board; and
a plurality of conductive stiffeners affixed to the backside of the flexible printed circuit board, each conductive stiffener electrically connecting at least one contact pad of the flexible printed circuit board to a bottom surface of the conductive stiffener and comprising:
a non-conductive substrate sheet;
a hole through the non-conductive substrate sheet; and
a conductive material forming a pad on a bottom surface of the non-conductive substrate sheet and lining the hole, wherein the pad of conductive material is electrically connected to a top surface of the non-conductive substrate sheet through the conductive material lining the hole,
wherein the conductive material forms a pad on the top surface of the non-conductive substrate sheet, and the pad of conductive material on the top surface comprises a thermal relief pattern in the conductive material surrounding the hole.

US Pat. No. 10,653,331

ELECTRODE SENSOR

Konan Medical USA, Inc., ...

1. An electrode sensor comprising:a conductive sensor area;
hydrogel at least partially covering the conductive sensor area, wherein the hydrogel is conductive and includes a surface configured to adhere to skin;
a receptacle forming an open container surrounding the conductive sensor area and the hydrogel, wherein the open container includes a front side with an opening and an opposing back side, the conductive sensor area and the hydrogel placed within the open container, with the surface of the hydrogel configured to adhere to skin facing the opening of the front side, and the conductive sensor area positioned closer to the back side than the hydrogel; and
a flange element having a first end affixed near the back side of the container, offset from a plane that is coincident with the surface of the hydrogel, and a second end extending laterally away from the container, wherein a distance between the first end of the flange element and the second end of the flange element is greater than a diameter of at least one of: the back side of the container or the front side of the container.

US Pat. No. 10,653,330

SYSTEM AND METHODS FOR PROCESSING NEURAL SIGNALS

PARADROMICS, INC., Austi...

1. A neural data analysis system comprising:an implantable neural interface probe configured to collect neural signal waveforms, wherein the neural interface probe comprises a massively parallel electrode array, wherein the massively parallel electrode array comprises a plurality of microelectrodes bonded to a readout integrated circuit (ROIC), and wherein the ROIC comprises a plurality of sensing pixels;
a feature extraction module comprising one or more low-power, mixed-signal integrated circuits, wherein the feature extraction module is configured to (1) extract a plurality of features from the neural signal waveforms without requiring prior digitization of the neural signal waveforms, and (2) transmit the extracted features as a plurality of discrete outputs;
a feature-event coalescence module configured to (1) receive the plurality of discrete outputs from the feature extraction module, (2) construct a model-based inference of bioelectric activity from the plurality of discrete outputs based in part on feature-event statistics, prior knowledge of bioelectric signals, and/or a behavioral model of the feature extraction module, wherein the model-based inference of bioelectric activity comprises a plurality of coalesced events, and each of the plurality of coalesced events comprises two or more discrete events that are coalesced; and
an approximator module configured to (1) receive the plurality of coalesced events from the feature-event coalescence module, and (2) apply a series of transformations to the plurality of coalesced events to generate a neural code, wherein the neural code comprises a representation of ensemble activity of a plurality of neurons recorded by the system.

US Pat. No. 10,653,329

PLANAR NEURAL PROBE STRUCTURE AND ITS ASSEMBLY STRUCTURE FOR CHRONIC IMPLANTATION

KOREA INSTITUTE OF SCIENC...

1. A neural probe structure configured to be fixed to a nerve to acquire an electrical signal from the nerve or apply an electrical stimulation to the nerve, the neural probe structure comprising:a body configured to extend around at least a part of a circumference of the nerve; and
a probe extending longitudinally from the body and configured to pass through the nerve,
wherein the body has a shape of a thin flat plate, and
wherein the neural probe structure is configured to be fixed to the nerve such that one side surface defining a thickness of the body stands facing a circumferential surface of the nerve.

US Pat. No. 10,653,328

BIOLOGICAL INFORMATION DETECTION DEVICE USING SECOND LIGHT FROM TARGET ONTO WHICH DOTS FORMED BY FIRST LIGHT ARE PROJECTED

Panasonic Intellectual Pr...

1. A biological information detection device comprising:a first light source that, in operation, projects first dots onto a target including a living body, and toward an area around the target, the first dots being formed by first light;
a second light source that, in operation, projects second dots onto the target, the second dots being formed by second light,
an image capturing device that, in operation, generates and outputs a first image signal representing a first image of the target onto which the first dots are projected and the area around the target, the image capturing device including first photodetector cells that, in operation, detect third light returning from the target onto which the first dots are projected; and
one or more arithmetic circuits, wherein:
the one or more arithmetic circuits, in operation, extract a first portion corresponding to at least a part of the living body from the first image by using the first image signal, and calculate biological information of the living body by using image signal of the first portion,
the first light includes light having a waveform that is greater than or equal to 650 nm and less than 800 nm,
the second light includes light having a waveform that is greater than or equal to 800 nm and less than or equal to 950 nm,
the image capturing device further includes second photodetector cells that, in operation, detect fourth light from the target onto which the second dots are projected, and
the image capturing device, in operation, generates and outputs a second image signal representing a second image of the target onto which the second dots are projected.

US Pat. No. 10,653,327

BIOLOGICAL INFORMATION DETECTION DEVICE

Seiko Epson Corporation, ...

1. A sensor comprising:a light emitting unit which irradiates a subject with light;
a first light receiving unit which receives the light from the subject;
a second light receiving unit which receives the light from the subject; and
a beam which is provided between the first light receiving unit and the second light receiving unit, in a plan view in a vertical direction of a light receiving surface of the first light receiving unit,
wherein
the first light receiving unit and the second light receiving unit are disposed along a first direction, and
when a first distance in the first direction between a first end portion of the beam on a first light receiving unit side and a second end portion of the first light receiving unit on a second light receiving unit side is set as LE1, and a second distance in the first direction between a third end portion of the beam on the second light receiving unit side and a fourth end portion of the second light receiving unit on the first light receiving unit side is set as LE2, a relationship of LE1>LE2 is satisfied.

US Pat. No. 10,653,326

DETECTION OF PATENT DUCTUS ARTERIOSUS USING PHOTOPLETHYSMOGRAPHY

The Feinstein Institutes ...

1. A system for detecting patent ductus arteriosus (PDA) in an infant comprising a photoplethysmograph having one or more channels, one or more computing devices comprising one or more processors, a memory unit, a display device, and a computer-readable storage medium including computer-readable code that is read by the one or more processors to perform a method comprising the steps of:a) obtaining or receiving electrocardiogram (ECG) signals from the infant;
b) obtaining or receiving photoplethysmographic (PPG) signals from a site on the upper body (UB) of the infant, and optionally from a foot (F) of the infant;
c) determining, for each PPG pulse a PPG pulse amplitude (AM), the AM defined as an amplitude between the end-diastolic maximum and the consecutive systolic decrease minimum for the UB PPG pulses;
d) determining the mean of one or more of the following parameters for a plurality of the PPG pulses:
(i) a relative pulse amplitude (rAM) by dividing the AM by the systolic decrease minimum to obtain a rAM for the upper body (rAM-UB) PPG pulses;
(ii) a pulse transit time (PTT-UB) between an R wave of the ECG and an onset of systolic decrease for the corresponding UB PPG pulse;
(iii) a ratio PTT-UB/rAM-UB between the pulse transit time (PTT-UB) and the relative pulse amplitude for the UB (rAM-UB) PPG pulse; and
(iv) a ratio rAM-UB/PTT-UB between the relative pulse amplitude for the UB (rAM-UB) PPG pulse and the pulse transit time (PTT-UB); and
e) detecting patent ductus arteriosus (PDA) in the infant when one or more of:
the relative pulse amplitude for the UB (rAM-UB) is elevated above normal,
the ratio PTT-UB/rAM-UB is decreased below normal, or
the ratio rAM-UB/PTT-UB is elevated above normal,
wherein the term “normal” refers to values of parameters obtained from infants with a closed ductus arteriosus.

US Pat. No. 10,653,325

SYSTEM AND METHOD FOR MEASURING ARTERIAL PRESSURE BY ITS EFFECTS

1. An arterial pressure measurement system comprising:an external contact force applying device applying an external contact force to a measurable artery;
a pressure sensor for measuring pressure of the applied external contact force and producing an electrical signal representing the measured pressure;
a flow sensor configured to be disposed on the measurable artery for detecting arterial expressions and producing an electrical signal representing the detected arterial expressions, wherein the flow sensor is selected from the group consisting of pressure sensor, laser sensor, vibration sensor and phonogram sensor;
a display; and
a motherboard in operable communications with the pressure sensor for receiving the electrical signal representing the measured pressure therefrom and with the flow sensor for receiving the electrical signal representing the arterial expressions therefrom, the motherboard being in operable communications with the display to convey information thereon, the motherboard being configured to:
engage the external contact force applying device to gradually apply the external contact force to the measurable artery;
during the gradual application of the external contact force, substantially continually receive the electrical signal representing the measured pressure from the pressure sensor;
during the gradual application of the external contact force, substantially continually receive the electrical signal representing the arterial expressions from the flow sensor when the arterial expressions are detected;
during the gradual application of the external contact force, perform signal differentiation on the received electrical signal representing the arterial expressions to identify an arterial cycle using amplitude, frequency and time of the electrical signal representing the arterial expressions such that high and low amplitudes depending on time are identified, where the arterial cycle comprises a systolic period defined by a systolic amplitude during a systolic time and a diastolic period defined by a diastolic amplitude that is lower than the systolic amplitude during a diastolic time that is longer than the systolic time;
during the gradual application of the external contact force and after the arterial cycle has been determined, identify a state of the arterial expressions, from the received electrical signals from the flow sensor during the diastolic period as being one of: not affected by the external contact force, affected by the external contact force but not occluded and occluded by the external contact force, where the state of occluded by the external contact force is identified when the received electrical signals representing the arterial expressions during the diastolic period have an amplitude that is zero or minimum amplitude;
after the arterial expressions are identified to be in the state of occluded by the external contact force during the diastolic period, determine a pressure applied by the external contact force from the received electrical signals representing the measured pressure at a time corresponding to the state of the arterial expressions being occluded by the external contact force during the diastolic period, the determined pressure representing a diastolic pressure;
during the gradual application of the external contact force and after the arterial cycle has been determined, identify a state of the arterial expressions, from the received electrical signals from the flow sensor during the systolic period as being one of: not affected by the external contact force, affected by the external contact force but not occluded and occluded by the external contact force, where the state of occluded by the external contact force is identified when the received electrical signals representing the arterial expressions during the systolic period have an amplitude that is zero or minimum amplitude;
after the arterial expressions are identified during the systolic period to be in the state of occluded by the external contact force, determine a pressure applied by the external contact force from the received electrical signals representing the measured pressure at a time corresponding to the state of the arterial expressions being occluded by the external contact force during the systolic period, the determined pressure representing a systolic pressure; and
provide the diastolic pressure and the systolic pressure to the display.

US Pat. No. 10,653,324

WRIST WORN CARBON MONOXIDE DETECTOR

1. An apparatus comprising:a band; and
a first device configured to attach to a person's wrist using the band;
wherein the first device includes a first carbon monoxide level detector;
wherein the first device includes a housing and a second device configured to be moved with respect to the housing from a first state to a second state;
wherein in the first state a person cannot blow into the second device and cause a carbon monoxide level of the person's breath to be detected by the first carbon monoxide level detector;
wherein in the second state the person can blow into the second device and cause a carbon monoxide level of the person's breath to be detected by the first carbon monoxide level detector;
wherein in the first state the second device covers an opening leading to the first carbon monoxide level detector so that a person's breath cannot be analyzed by the first carbon monoxide level detector through the second device; and
wherein in the second state the second device does not cover the opening leading to the first carbon monoxide detector, so that a person's breath can be analyzed by the first carbon monoxide level detector through the second device.

US Pat. No. 10,653,323

WEARABLE DEVICE

Thunder Power New Energy ...

1. A wearable device, comprises:a first sensor configured to generate a first signal of a subject wearing the wearable device;
a data transmission component configured to:
receive the first signal generated by the first sensor; and
transmit the first signal to a data analysis device to generate an alert instruction, wherein the data analysis device is configured to:
generate a first pattern of the subject based on the first signal;
determine whether the subject is functioning abnormally by comparing the first pattern with one or more predetermined abnormal patterns corresponding to one or more known conditions of the subject;
in response to a determination that the first pattern conforms to the one or more abnormal patterns, determine that the subject is functioning abnormally, and generate a first alert instruction;
transmit the first alert instruction to a monitoring device to generate a first notification for notifying a care-giver that the subject is functioning abnormally;
in response to a determination that the first pattern doesn't conform to the one or more abnormal patterns, determine whether the subject is functioning abnormally by comparing the first pattern with one or more predetermined normal patterns of the subject;
in response to a determination that the first pattern doesn't conform to the one or more normal patterns, determine that the subject is functioning abnormally, and generate a second alert instruction; and
transmit the second alert instruction to the monitoring device to generate a second notification for notifying the care-giver that the subject is functioning abnormally;
a first positioning component configured to provide a first location information of the wearable device in a first area; and
an alert component configured to be activated manually or automatically to generate an alert signal to indicate at least one of location of the wearable device or condition of the subject;
wherein the first notification is more noticeable to the care-giver than the second notification.

US Pat. No. 10,653,322

PHOTOACOUSTIC APPARATUS, METHOD OF ACQUIRING SUBJECT INFORMATION, AND NON-TRANSITORY COMPUTER READABLE MEDIUM

Canon Kabushiki Kaisha, ...

1. A photoacoustic apparatus comprising:a light source configured to generate a plurality of light beams having wavelengths ?1 and ?2 different from each other;
a conversion element configured to receive a photoacoustic wave that is generated in a subject in response to being illuminated with the light beams having wavelengths ?1 and ?2 different from each other and output a signal for each wavelength;
an information acquisition unit configured to acquire information in terms of a concentration of a substance existing in the subject by using the signal output for each wavelength; and
a specifying unit configured to specify a coefficient and instruct the information acquisition unit to use the specified coefficient in acquiring the information in terms of the concentration,
wherein the specifying unit specifies the coefficient as a single parameter ? in a formula (6)

where each one of ??1 and ??2 respectively denotes a light fluence in the different wavelengths ?1 and ?2, and each one of C?1 and C?2 respectively denotes an attenuation of the photoacoustic wave in association with the different wavelengths ?1 and ?2, and
wherein the information acquisition unit acquires information in terms of the concentration by using the coefficient specified by the specifying unit and the signal for each wavelength.

US Pat. No. 10,653,321

PHOTOACOUSTIC COMPUTED TOMOGRAPHY WITH A BIPLANAR ACOUSTIC REFLECTOR

Washington University, S...

1. A photoacoustic imaging system comprising an ultrasound transducer array and a planar acoustic reflector positioned on an opposite side of a planar imaging region; wherein:the planar acoustic reflector is configured to reflect one photoacoustic wave of a plurality of photoacoustic waves generated by a photoacoustic source within the planar imaging region to produce a reflected photoacoustic wave propagating toward the ultrasound transducer array, wherein the planar acoustic reflector includes two reflector planes intersecting each other at a non-zero angle; and
the ultrasound transducer array is configured to receive another photoacoustic wave of the plurality of photoacoustic waves, the other photoacoustic wave propagating directly from the photoacoustic source, and is further configured to receive the reflected photoacoustic wave.

US Pat. No. 10,653,320

VOLUME MAPPING USING OPTICAL SHAPE SENSORS

KONINKLIJKE PHILIPS N.V.,...

1. A volume mapping instrument deployable within an enclosed anatomical volume for mapping at least a portion of a boundary of the anatomical volume, the volume mapping instrument comprising:a medical tool including a medical tube having a helical shape deformable to elongated shape, the medical tube including shape memory material and being transitional between a deployable structural configuration wherein the medical tube has the deformed elongated shape to orderly position the medical tool within the anatomical volume and a mapping structural configuration wherein the medical tube has the helical shape to anchor the medical tube against the boundary of the anatomical volume; and
an optical shape sensor adjoined to the medical tube, the optical shape sensor being structurally configured to generate at least one encoded optical signal indicative of a shape of the at least a portion of a boundary of the anatomical volume in response to the medical tube being transitioned from the deployable structural configuration to the mapping structural configuration within the anatomical volume.

US Pat. No. 10,653,319

SYSTEM, APPARATUS AND METHOD FOR UTILIZING OPTICAL DISPERSION FOR FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY

The General Hospital Corp...

1. An apparatus, comprising:a laser to provide a laser radiation,
the laser including an optical cavity comprising:
a first dispersive element which receives and disperses a first electro-magnetic radiation and outputs a second electro-magnetic radiation,
a first phase modulator which receives and modulates the second electro-magnetic radiation and outputs a third electro-magnetic radiation,
a second dispersive element that receives and disperses the third electro-magnetic radiation and outputs a fourth electro-magnetic radiation, and
a second phase modulator which receives and modulates the fourth electro-magnetic radiation and outputs a fifth electro-magnetic radiation,
the laser radiation being based on at least one of:
 the first electro-magnetic radiation,
 the second electro-magnetic radiation,
 the third electro-magnetic radiation,
 the fourth electro-magnetic radiation, or
 the fifth electro-magnetic radiation.

US Pat. No. 10,653,318

LOCALIZATION SYSTEM AND METHOD USEFUL IN THE ACQUISITION AND ANALYSIS OF CARDIAC INFORMATION

ACUTUS MEDICAL, INC., Ca...

1. A localization system, comprising:at least one catheter configured for delivery of one or more biopotential electrodes to a body cavity defined by surrounding tissue;
a patient interface module comprising a plurality of localization electrodes configured for fixed orientation relative to the body, wherein the body cavity is a heart chamber and the surrounding tissue is one or more walls of the heart chamber; and
a cardiac information console configured to process both the magnitude and phase of localization signals from the localization electrodes to establish a manipulatable coordinate system for the tissue based on both the magnitude and phase of the localization signals,
and to process biopotential signals to orient the biopotential electrodes within the coordinate system.

US Pat. No. 10,653,317

ANALYTE MONITORING SYSTEM AND METHODS

Abbott Diabetes Care Inc....

1. An analyte monitoring device, comprising:an in vivo analyte sensor for positioning in fluid contact with bodily fluid under a skin surface; and
sensor electronics operatively coupled to the in vivo analyte sensor and comprising one or more components, and configured to:
receive signals corresponding to a measured analyte level from the in vivo analyte sensor;
store identification information for the sensor electronics;
receive a predefined command from a remote device;
transmit the stored identification information to the remote device;
receive synchronization data from the remote device;
modify an operation of the one or more components of the sensor electronics in response to the predefined command; and
transmit data for the signals corresponding to the measured analyte level from the in vivo analyte sensor and the synchronization data in real time.

US Pat. No. 10,653,316

ROLL-TO-ROLL MANUFACTURING METHOD OF WIRELESS NANOSENSOR

NANOWEAR INC., Brooklyn,...

1. A roll-to-roll printing process for manufacturing a wireless nanosensor monitoring system, comprising:continuously unwinding a fabric from a fabric roll;
printing an insulating base layer onto the fabric;
printing a conductive track layer on top of the insulating base layer;
printing an insulating cover layer on top of the conductive track layer;
printing an adhesive onto the fabric at a location along the conductive track layer and depositing vertically aligned nanostructures on the adhesive to provide a sensor connected to the conductive track layer; and
continuously winding the printed fabric into a printed fabric roll during all of the printing steps.