US Pat. No. 10,391,061

DELAYED RELEASE PHARMACEUTICAL FORMULATION AND METHODS OF MAKING AND USING SAME

Tillotts Pharma AG, Rhei...

1. A delayed release pharmaceutical formulation for delivering an active agent to the intestine, wherein said formulation comprises carrier particles and at least one active agent associated with the carrier particles, further wherein the carrier particles are porous particles that are surrounded by a material for colon targeting, further wherein the carrier particles comprise functionalized calcium carbonate, further wherein (a) the material for colon targeting comprises a compound which is susceptible to attack by colonic bacteria, and/or (b) the carrier particles are at least partially coated with either or both of a mucoadhesive compound and a sustained release coating.

US Pat. No. 10,391,058

PHARMACEUTICAL COMPOSITION COMBINING AT LEAST TWO DISTINCT NANOPARTICLES AND A PHARMACEUTICAL COMPOUND, PREPARATION AND USES THEREOF

NANOBIOTIX, Paris (FR)

1. A method for treating cancer comprising a step of administering at least one pharmaceutical anti-cancer compound to a subject in need thereof and a distinct step of administering at least two distinct biocompatible lipid-based nanoparticles to said subject, wherein the longest dimension of each of the at least two biocompatible nanoparticles is between about 4 nm and about 500 nm, the surface charge value of a first biocompatible nanoparticle is a negative charge below ?10 mV, the surface charge value of a second biocompatible nanoparticle, or of any additional biocompatible nanoparticle, is negative and has a difference of at least 10 mV to the negative surface charge value of the first biocompatible nanoparticle, each of the at least two biocompatible nanoparticles is not used as the at least, one pharmaceutical compound, and said at least two distinct biocompatible nanoparticles are administered to the subject separately from the at least one pharmaceutical compound between 4 hours and about 24 hours before said at least one pharmaceutical compound.

US Pat. No. 10,391,057

LIPOSOME COMPOSITION AND METHOD FOR PRODUCING SAME

FUJIFILM Corporation, To...

1. A liposome composition, comprising:liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed,
wherein the content of cholesterols is 17 mol % to 21 mol % with respect to the total amount of lipid components in the liposome composition,
each of the liposomes encapsulates a drug in a dissolved state, and the osmotic pressure of the inner water phase is 3-fold to 5-fold relative to the osmotic pressure of the outer water phase,
the release rate of the drug from the liposome composition in blood plasma is 10 wt %/24 hr to 70 wt %/24 hr relative to an initial encapsulation amount in the liposome composition,
the lipids constituting the liposome include at least hydrogenated soybean phosphatidylcholine, 1,2-distearoyl-3-phosphatidylethanolamine-polyethylene glycol, and cholesterol, and
the drug is an anticancer agent which is gemcitabine.

US Pat. No. 10,391,049

TOPICAL SKIN COMPOSITIONS FOR TREATING WRINKLES

Mary Kay Inc., Addison, ...

1. A method of treating a fine line or wrinkle in a person's skin, the method comprising topically applying to the fine line or wrinkle a composition comprising an effective amount of Commiphora mukul resin or an extract thereof that includes oleo gum resin, wherein topical application of the composition to the fine line or wrinkle reduces the appearance of the fine line or wrinkle.

US Pat. No. 10,391,043

EFFECT PIGMENTS WITH HIGH CHROMA AND HIGH BRILLIANCY, METHOD FOR THE PRODUCTION AND USE THEREOF

ECKART GMBH, Hartenstein...

1. An absorbent effect pigment comprising a nonmetallic substrate in platelet form and a coating applied to the substrate, wherein the coating comprisesa) optionally a layer 1 comprising or consisting of at least one of tin oxide, tin hydroxide or tin oxide hydrate,
b) a layer 2 having a high refractive index n>1.8, the layer 2 comprising at least one of metal oxide, metal hydroxide or metal oxide hydrate, and
c) a layer 3 having a high refractive index n>1.8, the layer 3 comprising at least one of metal oxide, metal hydroxide or metal oxide hydrate,
at least one of layers 2 and 3 comprises at least two different metal ions and layers 2 and 3 are interrupted by a spacer layer, wherein the at least one spacer layer comprises connections and cavities.

US Pat. No. 10,391,037

PORTABLE SMART MEDICINE CASE USING GUARDIAN NOTIFYING FUNCTION AND MEDICATION TIME NOTIFYING SYSTEM INCLUDING SAME

IOTEEN CO., LTD., Incheo...

1. A portable smart medicine case which comprises:a body 110 having a plurality of medicine chambers 111 to contain medicines M; a cover 120 covering the medicine chambers 111; and an electronic tag 130 provided on either the body 110 or the cover 120 of the medicine case to communicate with a user device 200 via NFC or RFID mode, the user device 200 being installed an alarm application which generates alarm signals when it becomes a medicine taking time, wherein, an alarm release information is stored on the electronic tag 130, and the electronic tag 130 transmits the alarm release information to the user device 200 when it is brought near to the user device 200 so that the alarm operation of the user device 200 is to be released,
wherein the body 110 is shaped so that the medicine chambers 111 having upper openings are disposed in series circumferentially, and a central chamber 112 having a lower opening and communicated with the medicine chamber 111 through air holes 117 is disposed on the central part of the body 110, the central chamber 112 includes a dehumidifier 150 to remove the humidity in the medicine chamber 111, and a central cover 160 to cover the lower opening of the central chamber 112.

US Pat. No. 10,391,036

MEDICINE CASSETTE, MEDICINE DISPENSING APPARATUS AND MEDICINE PACKAGING APPARATUS

YUYAMA MFG. CO., LTD., T...

1. A medicine dispensing apparatus comprising a medicine cassette, said medicine cassette comprising:a side-wall constituent body constituting a side-wall of a medicine containing part in which medicines should be contained;
a first rotating body which is arranged so as to be inclined from a bottom side toward an upper end side of the side-wall constituent body and can rotate around a first rotational axis;
a second rotating body which is arranged on an upper-side outer periphery of the side-wall constituent body and which can rotate around a second rotational axis; and
a medicine discharging part for discharging the medicines,
wherein the medicine cassette is configured to transfer and place the medicines prepared in the medicine containing part onto the second rotating body due to a rotation of the first rotating body and transfer the medicines toward a downstream side of a rotational direction of the second rotating body to discharge the medicines from the medicine discharging part, and
wherein a transferred medicine detecting device configured to detect the medicines in a transfer path to the medicine discharging part after the medicines are transferred and placed from the first rotating body onto the second rotating body is provided in the medicine cassette; and
a cassette control device for performing operation control for the medicine cassette,
wherein the cassette control device performs a transferring and placing operation for rotating the first rotating body to transfer and place the medicines in the medicine containing part onto the second rotating body on a condition that the medicine is not detected by the transferred medicine detecting device and rotates the first rotating body with a lower speed than that at the time of the transferring and placing operation, stops or irregularly rotates the first rotating body on a condition that the medicine is detected by the transferred medicine detecting device.

US Pat. No. 10,391,035

MEDICATION SYSTEM WITH A MEDICATION TRAY AND METHOD FOR CREATING A DELIVERY-READY MEDICATION SYSTEM

MEDINOXX GMBH, Inssbruck...

1. A medication system comprises:a medication tray having:
a rectangular tray sheet with a number of individual receiving sites, which are separated from each other and run in rows, and
a plurality of containers containing liquid or solid medicines, which are positioned in the receiving sites such that they are individually removable, each container of the plurality of containers has an upper edge with a level surface extending from a contoured outer edge to an upper opening in the level surface,
a plurality of plastic films welded on the plurality of containers, each container of the plurality of containers having a plastic film of the plurality of plastic films sealed to only the level surface of the upper edge to cover the upper opening, each plastic film of the plurality of plastic films having a film edge defined by a perforation along the contoured outer edge of the container welded thereto,
wherein:
the rectangular tray sheet is a re-usable plastic injection moulded part, and
each plastic film of the plurality of plastic films originates from a single flexible plastic film provided with a plurality of perforations along the contoured outer edges of the plurality of containers to define the film edge of each of the plurality of plastic films and a film mesh between the plurality of perforations, wherein the medication tray is devoid of the film mesh, which is removed from the plurality of plastic films at the plurality of perforations.

US Pat. No. 10,391,034

MULTIPLE-FLUID INJECTION PUMP

R.P. SCHERER TECHNOLOGIES...

1. A pump (100) for dispensing predetermined volumes of at least a first fluid (11A) and a second fluid (11B), the pump comprising:one or more first syringe units (55A), each first syringe unit (55A) comprising a first plunger (50A) and a first chamber (80A) within which the first plunger (50A) slides;
a first inlet channel (10A) fluidly connected to the first chamber (80A) of each first syringe unit (55A) and configured to receive the first fluid (11A);
one or more first discharge ports (20A) located in the first syringe unit (55A) at a location different from a location of the first inlet channel (10A) in the first syringe unit (55A), each first discharge port (20A) fluidly connected to the first chamber (80A) of a corresponding first syringe unit (55A), wherein each first syringe unit (55A) is operable to receive the first fluid (11A) via the first inlet channel (10A) and dispense a corresponding first predetermined volume of the first fluid (11A) via the corresponding first discharge port (20A) with every cycle of the corresponding first plunger (50A) sliding within the corresponding first chamber (80A);
one or more second syringe units (55B), each second syringe unit (55B) comprising a second plunger (50B) and a second chamber (80B) within which the second plunger (50B) slides;
a second inlet channel (10B) fluidly connected to the second chamber (80B) of each second syringe unit (55B) and configured to receive the second fluid (11B);
one or more second discharge ports (20B) located in the second syringe unit (55B) at a location different from a location of the second inlet channel (10B) in the second syringe unit (55B), each second discharge port (20B) fluidly connected to the second chamber (80B) of a corresponding second syringe unit (55B), wherein each second syringe unit (55B) is operable to receive the second fluid (11B) via the second inlet channel (10B) and dispense a corresponding second predetermined volume of the second fluid (11B) via the corresponding second discharge port (20B) with every cycle of the corresponding second plunger (50B) sliding within the corresponding second chamber (80B), such that:
the one or more first syringe units (55A) and the one or more second syringe units (55B) are configured to be operated by a single actuator in parallel such that when the first plunger (50A) moves to cause the first fluid (11A) to fill the first chamber (80A) the second plunger (50B) moves to cause the second fluid (11B) to discharge from the second chamber (80B), and
when the second plunger (50B) moves to cause the second fluid (11B) to fill the second chamber (80B) the first plunger (50A) moves to cause the first fluid (11A) to discharge from the first chamber (80A),
the one or more first discharge ports (20A) and the one or more second discharge ports (20B) fluidly configured to deliver the first and second fluids (11A, 11B) to one or more common locations, whereby each common location receives both the first predetermined volume of the first fluid (11A) and the second predetermined volume of the second fluid (11B).

US Pat. No. 10,391,033

MEDICATION DOSE PREPARATION AND TRANSFER SYSTEM

CRISI Medical Systems, In...

1. An apparatus for transferring medication from a primary medication container to a secondary medication container, comprising:a housing having a fluid channel extending between a primary medication container port and a secondary medication container port;
a secondary medication container coupling configured to fluidically couple the secondary medication container to the secondary medication container port;
at least one identification sensor disposed within the housing adjacent the secondary medication port, the at least one identification sensor configured to sense an information transfer element on the secondary medication container, the information transfer element on the secondary medication container identifying the secondary medication container; and
a communication module to transmit information obtained by and/or derived from the at least one identification sensor to a remote computing system.

US Pat. No. 10,391,032

STERILIZABLE FLEXIBLE PACKAGE FOR THE RECONSTITUTION AND ADMINISTRATION OF FLUID MEDICINAL OR NUTRITIONAL SUBSTANCES WHICH ARE INFUSED OR INSTILLABLE WITHIN THE BODY OF A PATIENT

PAOLO GOBBI FRATTINI S.R....

1. A package for reconstitution and administration of fluid medicinal or nutritional substances which are infused or instillable within the body of a patient, comprising a flexible casing containing a vial with closing cap for medicinal or nutritional substance, which vial is in coupling position with a coupling and perforation device inserted into a mixing tube for the connection with a bag of liquid diluent, wherein said coupling, and perforation device comprises a first element slidably coupled with a second element and movable between a vial coupling position and a vial cap perforating position, wherein said first element comprises a ring from which at least two flaps vertically extend which are provided with notches suitable to receive the vial in engagement position, and an operable closure surmounted by a circular base from the perimeter of which further adjacent flaps vertically extend, which are equipped with notches suitable to accommodate the vial in the vial cap perforating position, and said ring is inserted outside said additional flaps and is configured to slide coaxially with respect to the circular base, and said further flaps have a curvature at their free ends such as to constitute a first limit for said first element with respect to the vial in the vial coupling position, and said notches are configured to contrast with said circular base and form a second limit for said first element with respect to the vial in the vial cap perforating position, wherein said flexible casing further comprises a connector provided with an openable and hermetically reclosable cap, suitable for the introduction of a mixture of sterilizing gas and oxygen within said casing.

US Pat. No. 10,391,031

ADAPTER FOR VIAL ACCESS DEVICE

Becton Diskinson and Comp...

1. A system selectively attachable to a first vial defining a first vial size and a second vial defining a second vial size, the second vial size different than the first vial size, the system comprising:a vial access device including a spike, the vial access device directly attachable to the first vial, the vial access device having a first connection element attachable to the first vial to secure the vial access device to the first vial; and
an adapter movable relative to the vial access device between a shield position in which the adapter is attachable to the vial access device such that the adapter shields the spike of the vial access device and a vial position in which the adapter is attachable to the second vial.

US Pat. No. 10,391,030

RECEPTION, DRAINING AND TRANSFER OF A HIGH QUANTITY OF BIOPHARMACEUTICAL FLUID UNDER PRESSURE WITH A VIEW TO SUBSEQUENT TREATMENT

SARTORIUS STEDIM FMT SAS,...

1. A device for the reception and then the draining of a large amount of biopharmaceutical fluid, at least equal to about 10 liters, under controlled pressure by a laboratory which prepares pharmaceutical products, for the purposes of further treatment such as filtration, final formulation, and/or filling containers of smaller capacity, wherein the device comprises:an inner bag made of plastic, flexible and fluidtight, having an inner container intended and suitable for receiving a quantity at least equal to about 10 liters of biopharmaceutical fluid and provided with a filling port for supplying the biopharmaceutical fluid and a drain port for emptying the biopharmaceutical fluid, and connected in a fluidtight manner to the filling port and drain port, a filling tube having an inlet for filling the inner container with biopharmaceutical fluid, adapted to be connected to a filling line for the biopharmaceutical fluid, and a drain tube having an outlet for draining the inner container of biopharmaceutical fluid, adapted to be connected to a drain line for the biopharmaceutical fluid,
an outer container into which the inner bag is placed, a compression chamber being formed between the outer container and the inner bag for which the filling inlet and drain outlet are located externally to the outer container, a port for injecting pressurized draining gas into the compression chamber being provided on said outer container,
fluidtight passages through the outer container via the filling tube and drain tube,
an integrated means for bleeding the gas filling the filling line prior to filling with biopharmaceutical fluid, so that this gas does not enter the inner bag, and
the respective deformation capacities of the inner bag and outer container being chosen such that when injecting the pressurized draining gas into the compression chamber, the inner bag is compressed and the pressure causes the biopharmaceutical fluid contained therein to empty through the drain outlet, wherein:
the outer container comprises a fluidtight outer receptacle made of plastic, forming an outer chamber into which the inner bag is placed, defining the compression chamber, and comprising the injection port for the pressurized draining gas,
the filling tube and drain tube pass through the outer receptacle via fixed permanent connections, the filling inlet and drain outlet being located externally to the outer receptacle, and
the outer receptacle and the inner bag form a coherent whole that is disposable.

US Pat. No. 10,391,029

PTP SHEET FOR DRUG PACKAGING

NIPRO CORPORATION, (JP)

1. A PTP sheet for packaging a pharmaceutical drug, comprising:a first sheet and a second sheet, the first sheet having a surface facing the second sheet, the first sheet having a first portion and a pocket portion, the first portion being in contact with the second sheet;
the pocket portion having sidewalls and a base portion, the pocket portion configured for holding the pharmaceutical drug;
wherein the sidewalls of the pocket portion have a wall thickness less than the wall thickness of the base portion and the first portion;
wherein the base portion has a wall thickness equal to the wall thickness of the first portion of the first sheet; and
wherein a first force, applied to the base portion in a direction normal to a plane defined by the first portion, that drives the base portion just to said plane is less than three times a second force applied normal to the base portion in said direction that causes yield point rupture of the second sheet.

US Pat. No. 10,391,028

SECURE PILL CONTAINER

1. A secure pharmaceutical container, comprising:a housing comprising a first group of compartments wherein each compartment comprises an opening that engages with a lid secured in a closed position by a first locking mechanism, and a second group of compartments wherein each compartment comprises an opening that engages with a lid secured in a closed position by a second locking mechanism;
an electronic computing system comprising a non-transitory computer readable medium, a first biometric system operably connected to the first locking mechanism and configured to actuate the first locking mechanism, and a second biometric system operably connected to the second locking mechanism and configured to actuate the second locking mechanism;
the housing and the electronic computing system are physically connected;
the compartments of the first group of compartments are arranged linearly in a first row, and wherein the compartments of the second group of compartments are arranged linearly in a second row, wherein the first row and the second row are parallel to each other, and wherein the openings and the lids are all on one side of the housing;
the first biometric system comprises a first fingerprint scanner attached to a first surface of the housing adjacent to the first row of compartments;
the second biometric system comprises a second fingerprint scanner attached to a second surface of the housing adjacent to the second row of compartments.

US Pat. No. 10,391,027

PILL ORGANIZER AND DISPENSER

1. A pill loading device for positioning pills into a pill storage container, comprising:a housing having an array of openings formed on a top wall of the housing, the array comprising two or more rows of openings extending in a left-to-right, lateral direction of the housing and two or more columns of openings extending in a front-to-back, transverse direction of the housing, the housing defining a cavity beneath the array of openings;
a user-operable sorting plate assembly, positioned beneath the array of openings and carried by the housing in a transversely movable relationship with the housing, the sorting plate assembly operable from outside the housing to move transversely relative to the housing, the sorting plate assembly comprising two or more user-operable slides laterally movable relative to one another; wherein
each slide is arranged under a respective row of the two or more rows of openings and extending across the respective row, and is operable from outside the housing to move transversely relative to the housing, and further wherein
each slide comprises a first portion having transversely interspersed and aligned solid portions and open portions, said solid portions and open portions divided into at least two pairs of a solid portion and an open portion, wherein each slide is transversely movable to a first transverse position in which the slide is laterally movable relative to the housing to adopt:
a position in which the solid portions of the slide are aligned with the openings of the respective row, preventing a pill from passing through the opening and into the cavity of the housing, and
an alternative position in which the open portions of the slide are aligned with the openings of the respective row, allowing a pill to pass through the opening and into the cavity of the housing.

US Pat. No. 10,391,026

BODY DRYER

1. A system for delivering heated air streams into a shower enclosure comprising:a heated air source;
a conduit providing air flow communication between the heated air source to a first panel having a plurality of spaced air jets for forming heated air streams directed downward through;
a second panel having a plurality of spaced air vents for directing heated air flow into the shower enclosure,
wherein the second panel is disposed below the first panel and on a top end of the shower enclosure;
a computerized control unit disposed on an outside of a shower enclosure door; and
an air exhaust unit, which is disposed at a lower section of the shower enclosure and on at least one side of a shower enclosure wall,
wherein the control unit comprises a plurality of air-flow sensors, a plurality of temperature sensors, a touch-sensitive switch, a digital display, a CPU, and memory;
wherein the heated air source comprises an air intake, an air heater and an air blower, and wherein the air heater and blower are operatively associated with, while independently regulated by the control unit; and
wherein the heated air flow produced by the heated air source flows through the conduit to and through the first panel, prior to flowing through the second panel into an interior of the shower enclosure, and eventually exits through the air exhaust unit out of the shower enclosure.

US Pat. No. 10,391,025

EYE MASSAGING DEVICE

1. An eye massaging device, comprising:a main body, having a front mounting portion and a rear mounting portion arranged opposite to each other, a circulating water tank, a heating member, and a circulating pump are arranged on the front mounting portion, the heating member is stacked on the circulating water tank, and the circulating pump is fluidly communicated with the circulating water tank via a heating pipe;
a water bag, arranged at the rear mounting portion, the water bag includes an outer frame portion, an affixing portion for touching a peripheral of two eyes, and a receiving portion, the affixing portion is arranged at an inner edge of the outer frame portion, and an peripheral of the receiving portion is arranged at the affixing portion, a flow guiding passage is formed between the receiving portion and the affixing portion, two concave areas are arranged at the affixing portion so as to avoid the eyes, a thickness of the affixing portion is thicker than a thickness of the outer frame portion, a circulating pipe is passed through the main body, a first portion of the circulating pipe is fluidly communicated between the circulating pump and a location of the flow guiding passage of the water bag, and a second portion of the circulating pipe is fluidly communicated between the circulating water tank and another location of the flow guiding passage of the water bag;
a control unit, arranged at the front mounting portion of the main body, the control unit includes a thermal sensor for sensing a temperature of the circulating water tank and a microprocessor, the microprocessor is electrically connected to the thermal sensor, the circulating pump, and the heating member;
a cover, used for receiving the circulating water tank, the heating member, the circulating pump, the control unit, the heating pipe, and part of the circulating pipe and fastened at the front mounting portion of the main body; and
a fixing ring, surrounded a peripheral of the water bag and fixed at the rear mounting portion of the main body with the water bag.

US Pat. No. 10,391,024

DEVICE FOR CREATING THE ILLUSION OF PENETRATION

THIKA HOLDINGS LLC, St. ...

1. A sex toy comprising:an elastic housing connected to a tip at a first end and a base at a second end; and
a spring arranged within the elastic housing with a first spring end engaged against the tip and a second spring end engaged against the base;
wherein (1) in an initial state, the spring is configured to be in an extended state, and in such initial state the sex toy has a first longitudinal length, and
(2) in a secondary state, the spring is configured to be compressed within the housing along a longitudinal axis (X) such that the elastic housing compresses and the sex toy is compressed to a second longitudinal length that is less than the first longitudinal length in response to the tip engaging against a user's body to thereby apply pressure to the sex toy.

US Pat. No. 10,391,023

COLD FOOT PAIN RELIEVER

1. A heat removal relief device comprising:a spherical container having a thermally conductive surface and defining a first hole, and a second hole;
a tube defining a channel, provided through the first hole and the second hole, and sealed into watertight engagement with the spherical container in a configuration that defines a watertight, at least partially hollow, interior within the spherical container;
a fluid mixture provided within the watertight, at least partially hollow, interior within the spherical interior;
wherein the fluid mixture comprises:
crosslinked, water-absorbing polymer;
water; and
a flexible strap provided through the channel of the tube.

US Pat. No. 10,391,022

LEG MUSCLE THERAPY APPARATUS

1. A leg muscle therapy apparatus comprising:two main support members, each of said main support members comprising a support structure member having a first end and a second end;
a coupling member for pivotally coupling the first ends of said main support members together so that the support structure member of each of said main support members may pivotally move away and towards one another;
at least one user engagement member pivotally mounted to each of said support structure members such that said at least one user engagement member pivots toward and away from an inner surface of said support structure member, said at least one user engagement member having a curved inner surface with said at least one user engaging element mounted thereon; said at least one user engaging element having an outward surface of which is generally concave in shape;
whereby each of said main support members of said leg muscle therapy apparatus may be positioned around a leg of a user in such a manner that the user maymove said main support members along the contours of the leg, in both a linear and circular motion, such that said at least one user engaging element mounted to said inner surface of each of said at least one user engagement member may engage the leg of the user, with said coupling member allowing said main support members to pivotally move away and towards one another as varying contours of the leg are being engaged, thereby providing a muscle therapy routine on the leg of the user.

US Pat. No. 10,391,021

MASSAGE HEAD AND MASSAGE APPARATUS USING SUCH A HEAD

LPG Systems, Valence (FR...

1. A massage head comprising a casing defining an internal chamber configured to have a skinfold formed therein when the massage head is applied to a patient's skin, said fold configured to come into contact with the lower edges of the chamber, said chamber being defined by two lateral walls and by two transverse walls, at least one of said transverse walls being formed of a flap capable of having a pivoting motion, to induce the coming closer and the drawing away from each other of the lower edges of said transverse walls configured to be in contact with the skinfold:wherein said at least one flap is hinged in the vicinity of its upper end on the lateral walls; and
wherein the pivoting of the flap is obtained by means of a geared motor fixedly assembled within said flap, an output shaft of said geared-motor rotating a cam, received in a cam race rigidly attached to one of the lateral walls of the internal chamber.

US Pat. No. 10,391,020

ARM THERAPY DEVICE

Bymers and Johnson Therap...

1. An arm therapy device, comprising:a housing comprising an upper end, a lower end, a first side, a second side, and an upper opening;
a first slot extending across the first side of the housing;
a second slot extending across the second side of the housing;
a first roller movably positioned within the first slot and the second slot such that the first roller extends between the first side and the second side of the housing;
a first collar connected to the first roller, the first collar being positioned externally with respect to the housing, wherein the first collar comprises a first threaded connector, the first threaded connector being threadably and removably connected to the first roller;
a second roller movably positioned within the first slot and the second slot such that the second roller extends between the first side and the second side of the housing;
a second collar connected to the second roller, the second collar being positioned externally with respect to the housing, wherein the second collar comprises a second threaded connector, the second threaded connector being threadably and removably connected to the second roller; and
a bias member connected between the first collar and the second roller collar such that the first roller and the second roller are each biased toward each other.

US Pat. No. 10,391,019

PATIENT SUPPORT WITH UNIVERSAL ENERGY SUPPLY SYSTEM

Stryker Corporation, Kal...

1. A patient support comprising:a patient support surface for supporting a patient thereon, said patient support having a mattress with at least one inflatable bladder and a pneumatic system, said pneumatic system being in fluid communication with the inflatable bladder and including a plurality of ports mounted to said patient support, each of said ports being accessible by a user for coupling an external device to said pneumatic system;
a DVT assembly having a housing and a DVT pump mounted in said housing, said DVT assembly being configured to mount to said patient support relative to said patient support surface, and when mounted to said patient support said DVT pump configured to be in fluid communication with said pneumatic system of said patient support
for delivering fluid to at least one port of said ports, and said at least one said port configured for coupling to a DVT device for delivering fluid to the DVT device from said DVT pump when the DVT pump is in fluid communication with said pneumatic system of said patient support and after a user has coupled the DVT device to said at least one port; and
a patient support control system mounted in said patient support to control one more of components of said patient support and configured to communicate with the DVT assembly, and said control system configured to send signals to the DVT assembly to control the DVT pump.

US Pat. No. 10,391,018

WALK AGAIN WALKER

1. A collapsible upright wheeled walker device for augmenting an upright partially-supported walking gait on a walking surface for an unassisted user, the device comprising:a frame having right, left, and back sides, the sides folding in on themselves for compact storage and transport;
two front wheel assemblies and two rear wheel assemblies coupled to the frame for supporting the frame above the walking surface and apportioned at the vertices of a polygonal footprint on the walking surface within which the user walks during use;
the frame having a simultaneously adjustable height and depth provided by lock-in-place slidable supports that cooperate with slidable lock-in-place front-to-rear adjustable support braces;
wherein the frame collapses to a compact structure via V-folder hinges located at two posterior and four side hinges;
two upper supports each coupled to and disposed at an adjustable height above a respective frame side; and
two handles, each coupled to a respective upper anterior support for gripping by the user, the handles disposed at a forward handle angle with respect to the device and having locking handbrake levers used to actuate a cable connected to a friction brake at each of the respective rear wheel assemblies.

US Pat. No. 10,391,017

ANGLE ADJUSTABLE CRUTCH HANDLE

First Freedom Financial, ...

1. An angle adjustable crutch handle comprising:a) a handle-grip comprising:
i) a first end;
ii) a second end; and
iii) a first fastener opening on the first end;
b) a first adjustment adapter configured on the first end of the handle-grip;
second adjustment adapter configured on the second end of the handle-grip;
wherein each of the first and second adjustment adapters comprise:
a fastener slot that extends from an extended slot end to a connected slot end;
a curved outer surface;
wherein the first fastener opening is configured between the handle-grip and the first adjustment adapter to receive a first fastener head of a first fastener that extends through the first fastener slot; and
wherein a second fastener extends through the second fastener slot;
wherein the first and second fasteners retain the angle adjustable crutch handle to a crutch;
d) a first crutch adapter that extends around a first crutch support and engages with the curved outer surface of the first adjustment adapter;
e) a second crutch adapter that extends around a second crutch support and engages with the curved outer surface of the second adjustment adapter
wherein the first fastener extends through the first crutch adapter; and
wherein the second fastener extends through the second crutch adapter.

US Pat. No. 10,391,016

MACHINE TO HUMAN INTERFACES FOR COMMUNICATION FROM A LOWER EXTREMITY ORTHOTIC

Ekso Bionics, Inc., Rich...

1. A lower extremity orthosis configured to be coupled to a person, the orthosis comprising:a torso link configured to be coupled to a torso of the person,
at least one leg link configured to be coupled to a leg of the person,
at least one actuator configured to shift the at least one leg link with respect to the torso link,
a plurality of sensors configured to measure at least one of an orientation and forces of the orthosis and the person,
a controller configured to receive signals from the plurality of sensors, estimate at least one feedback ready value based on signals from the plurality of sensors, and control the at least one actuator to assist a gait or movement of the person, and
at least one feedback system operated by the controller and configured to communicate the at least one feedback ready value to the person, whereby the orthosis provides the person with orthosis operational information not otherwise available to the person, wherein the at least one feedback system includes at least one of (1) at least one light corresponding to each of the at least one actuator, the at least one light indicating an effort being produced by the orthosis at that corresponding actuator, and (2) a display mounted in a field of view of the person, the display overlaying graphics so that the graphics indicate locations on a support surface.

US Pat. No. 10,391,015

APPARATUS AND METHOD FOR RESTORING VOLUNTARY CONTROL OF LOCOMOTION IN NEUROMOTOR IMPAIRMENTS

Ecole Polytechnique Feder...

1. A pharmaceutical composition comprising a combination of synthetic agonists to monoaminergic receptors for use in restoring voluntary motor control in a subject suffering from a neuromotor impairment, wherein the synthetic agonists are at least two of agonists of 5HT1A, 5HT2A/C, 5HT7, and DA1-like receptors and wherein the synthetic agonists are 8-OH-DPAT, quipazine, and SKF-81297.

US Pat. No. 10,391,014

SURGICAL POSITIONING SYSTEM

Allen Medical Systems, In...

1. A surgical positioning device for use with a patient, the surgical positioning device comprisinga flexible air impermeable shell having an interior region, the shell having an outer periphery defined by an upper edge, a lower edge and opposite lateral edges extending between the upper edge and the lower edge, the shell being shaped to underlie a patient's torso during surgery and to wrap around the patient's shoulders during surgery, and
a plurality of beads substantially filling the interior region of the shell and permitting the shell to be pliable prior to evacuation of air from the interior region so that the shell is able to be wrapped around portions of the patient, the shell rigidifying in response to air being evacuated from the interior region, wherein the shell has shoulder portions that wrap around the patient's shoulders, wherein the upper edge of the shell is shaped so that when the shell is lying flat, the shoulder portions extend in a longitudinal dimension of the surgical positioning device beyond a central region of the upper edge defined between the shoulder portions such that the surgical positioning device is devoid of any structure that extends in the longitudinal dimension beyond the shoulder portions.

US Pat. No. 10,391,013

POWERED AMBULANCE COT WITH AN AUTOMATED COT CONTROL SYSTEM

Ferno-Washington, Inc., ...

1. A powered ambulance cot for transporting a patient above a surface, comprising:a support frame for supporting the patient above the surface;
four legs, each leg having a wheel for supporting the cot on the surface;
a pair of actuators, each actuator interconnects the support frame and a respective pair of the legs and effects changes in position of the wheels of each respective pair of the legs relative to the support frame;
a motor controller which controls the pair of actuators individually to raise and lower the wheels of each respective pair of the legs with respect to the support frame according to a mode selection from a plurality of mode selections; and
a graphical user interface (GUI) controller which, via an electrically connected graphical user interface (GUI), receives an input of the mode selection from among the plurality of mode selections and outputs a matching image on the GUI of the selected mode.

US Pat. No. 10,391,012

SYSTEM, METHOD, AND COMPUTER ALGORITHM AND CHARACTERIZATION AND CLASSIFICATION OF ELECTROPHYSIOLOGICAL EVOKED POTENTIALS

SafeOp Surgical Inc., St...

1. When somatosensory EP waveforms are acquired, a method of automatically identifying potential injury to peripheral nerve structures comprising:causing, by an automated EP analysis apparatus with an electrical pulse via electrodes, stimulation of a peripheral nerve structure, the automated EP analysis apparatus having a processor and memory;
recording, by the automated EP analysis apparatus via electrodes placed at the neck or head, signals forming a resultant electrical (EP) waveform generated by the nervous system;
measuring, by the automated EP analysis apparatus, a change in the recorded EP waveform relative to a baseline response, the change comprising Euclidean distance between the recorded EP waveform and the baseline response;
comparing, by the automated EP analysis apparatus, the change with one or more threshold change values to classify the recorded EP waveform; and
determining, by the automated EP analysis apparatus, whether a current state of the peripheral nerve structure has changed based on the classification of the recorded EP waveform by determining whether a count of EP waveforms in a classification exceeds a threshold count value.

US Pat. No. 10,391,011

ADJUSTABLE SUPPORT POLE HANDLE

Stander Inc., Logan, UT ...

1. A support pole, comprising:a support member comprising a longitudinal axis, a first support portion, and a second support portion, wherein the first support portion and the second support portion comprise an external groove that extends along the longitudinal axis and aligns when the support portions are assembled to inhibit rotational displacement of each support portion relative to each other;
a floor mount coupled to a first end of the support member;
a ceiling mount coupled to a second end opposite the first end of the support member;
a height adjustment component coupled to support member, wherein the height adjustment component is configured to adjust a length of the support member between the first end and the second end, wherein the height adjustment component is disposed between the first support portion and the second support portion, wherein the height adjustment component comprises a first threaded portion and a second threaded portion, wherein the first threaded portion is coupled to the first support portion and the second threaded portion is coupled to the second support portion; and
a handle coupled to the support member, wherein the handle is positionable 360 degrees about the support member and along the longitudinal axis between the first end and the second end.

US Pat. No. 10,391,010

SLEEP DISORDER TREATMENT DEVICES, SYSTEMS, AND METHODS

Hill-Rom Services, Inc., ...

1. A sleep disorder treatment system, comprising:a mattress may have a longitudinal length defined by a longitudinal axis of the mattress when the mattress is in its most horizontal position and a lateral width defined by a lateral axis of the mattress when the mattress is in its most horizontal position, wherein the mattress comprises:
a head section having a head support surface to support at least a portion of a person's head, wherein at least a portion of the head support surface is generally sloped in the lateral direction at an angle relative the lateral axis, wherein the angle of the head support surface is from about 10 degrees to about 30 degrees; and
a torso section having a torso support surface to support at least a portion of a person's torso, wherein the torso support surface is generally sloped in the lateral direction at an angle relative to the lateral axis, and wherein the torso support section comprises a cradle surface extending downwardly and laterally from near one side of the torso support section to an opposite side of the torso support section, the cradle surface being provided by a rigid curved plate embedded in foam at an upper region of the torso support section.

US Pat. No. 10,391,009

OPTIMIZATION OF THE OPERATION OF A PATIENT-SUPPORT APPARATUS BASED ON PATIENT RESPONSE

Hill-Rom Services, Inc., ...

1. A patient-support apparatus comprisinga plurality of bladders,
a plurality of pressure sensors coupled to the plurality of bladders and configured to produce pressure signals indicative of air pressure within the plurality of bladders, and
a controller in electrical communication with the plurality of pressure sensors, the controller configured to determine an expected first patient outcome associated with an expected position of a patient due to migration of the patient to a position near a foot end of the patient support apparatus over a time interval based on a patient-specific profile and an operating parameter of the patient-support apparatus and the controller is further configured to determine an actual first patient outcome associated with an actual first position of the patient due to migration of the patient toward a foot end of the patient support apparatus over a time interval and to adjust target pressures for the plurality of bladders based on a comparison of the actual first patient outcome and the expected first patient outcome.

US Pat. No. 10,391,008

PATIENT SUPPORT SYSTEM AND METHODS OF USE

Hill-Rom Services, Inc., ...

1. A patient support system comprisinga base including a lower frame, an upper frame mounted above the lower frame, a lift system configured to move the upper frame relative to the lower frame, and an obstruction sensor configured to detect the presence and the location of obstructions present between the lower frame and the upper frame,
and a control system including a user interface and a controller coupled to the obstruction sensor, the controller configured to activate one or more of fault indicators on the user interface based on inputs from the obstruction sensor included in the base, wherein each of the fault indicators activated is associated with one of a head end of the patient support system, a foot end of the patient support system, a left side of the patient support system, and a right side of the patient support system so that a caregiver can remove obstructions from specifically identified locations without visually inspecting between the lower frame and the upper frame,
wherein the user interface includes a graphic representation of the patient support system, fault indicators associated with the head end of the patient support system are arranged along a head end of the graphic representation of the patient support system, fault indicators associated with the foot end of the patient support system are arranged along a foot end of the graphic representation of the patient support system, fault indicators associated with the left side of the patient support system are arranged along a left side of the graphic representation of the patient support system, and fault indicators associated with the right side of the patient support system are arranged along a right side of the graphic representation of the patient support system.

US Pat. No. 10,391,007

ELEVATABLE AND PORTABLE WHEELCHAIR

1. A wheelchair comprising:a lower assembly including a lower frame having wheels rotatably mounted thereto;
an upper assembly including an upper frame supporting a seat, a backrest and at least one movable armrest; and
a lift mechanism configured to move the upper assembly relative to the lower assembly between a lowered position and a raised position, wherein a user can move sideways out of the seat in the raised position with the movable armrest lowered, wherein the upper assembly includes upper struts pivotally connected between the upper frame and the lift mechanism, wherein the lower assembly includes lower struts pivotally connected between the lower frame and the lift mechanism, and wherein the upper struts, the lower struts, the lower assembly, the upper assembly and the lift mechanism are configured to enable folding of the wheelchair for storage and/or transport.

US Pat. No. 10,391,006

POWERED ROLL-IN COTS HAVING WHEEL ALIGNMENT MECHANISMS

Ferno-Washington, Inc., ...

1. A roll-in cot comprising:a support frame comprising a front end and a back end;
a front pair of legs at least one of pivotably coupled and slidingly coupled to the support frame;
a front hinge member pivotably coupled to the support frame and to one of the front pair of legs;
a front wheel linkage pivotably coupled to the front pair of legs;
a rear pair of legs at least one of pivotably coupled and slidingly coupled to the support frame;
a rear hinge member pivotably coupled to the support frame and to one of the rear pair of legs;
a rear wheel linkage pivotably coupled to the rear pair of legs; and
a wheel alignment mechanism incorporated into at least one of the front or rear pairs of legs, wherein:
the front pair of legs and the rear pair of legs are pivotable relative to the support frame and independently of one another;
the front pair of legs and the front pair of hinge members pivot relative to one another in a relative angular rotation ratio;
the rear pair of legs and the rear pair of hinge members pivot relative to one another in a relative angular rotation ratio;
the wheel alignment mechanism rotates at least one of the respective wheel linkages relative to the respective pair of legs at a reduction ratio, the wheel alignment mechanism comprising:
a first hub held forming a pivot point about a location where the corresponding front or rear hinge member is coupled to the respective pair of legs through a fixed position relative to the corresponding front or rear hinge member and a rotatable position relative to the respective pair of legs;
a second hub forming a pivot point about a location where the corresponding front or rear wheel linkage is coupled to the respective pair of legs through a fixed position relative to the corresponding front or rear wheel linkage and a rotatable position relative to the respective pair of legs; and
a timing mechanism rotationally coupled to and extending between the first and second hubs and rigidly coupled to at least one of the first and second hubs along at least a portion of an outer periphery of the corresponding first or second hub through at least one attachment plate such that upon raising or lowering of the respective pair of legs, the timing mechanism transmits relative rotational movement between the respective pair of legs and corresponding front or rear hinge member into a corresponding rotation of the respective wheel linkage in proportion to relative diameter differences of the first and second hubs in order to maintain a relative angular inclination of the respective wheel linkage to a ground surface.

US Pat. No. 10,391,005

DIAPER ATTACHMENT SYSTEM

YKK Corporation, (JP)

11. An attachment tab for use with a diaper comprising:a fastening portion comprising a handle portion disposed at a distal edge of the fastening portion and a grip portion;
wherein the grip portion is disposed between the handle portion and a proximal edge of the fastening portion;
wherein the grip portion is configured to removably attach to a second end;
wherein the fastening portion comprises at least one cut portion extending through an entire thickness of the fastening portion;
wherein during disengagement of the fastening portion from the second end, the diaper is configured such that a peeling force resists detachment of the fastening portion from the second end before detachment of the fastening portion reaches a pair of end points of the at least one cut portion; and
wherein during disengagement of the fastening portion from the second end, the diaper is configured such that a shear force resists detachment of the fastening portion from the second end after the detachment of the fastening portion reaches the pair of end points of the at least one cut portion.

US Pat. No. 10,391,004

COMPOSTABLE DIAPER AND METHOD OF MANUFACTURING THEREOF

1. A diaper comprising a biodegradable topsheet, a biodegradable absorbent core and a biodegradable bottom sheet, wherein the bottom sheet is liquid impervious and wherein the top sheet is configured for transmission of bodily fluids to the absorbent core, wherein the absorbent core comprises a first and a second non-woven layer comprising pulp fibers, and in between thereof a composting-stimulating layer comprising charcoal wherein the composting-stimulating layer is present in an amount of 8-30 wt % based on the total diaper.

US Pat. No. 10,391,001

ABSORBENT ARTICLE

DAIO PAPER CORPORATION, ...

1. An absorbent article comprising:an absorbent body provided between a liquid permeable topsheet and a backsheet, a convex portion of the absorbent body that is high toward a skin side being formed at a skin side surface of the absorbent body at a center portion in a width direction,
wherein the convex portion includes
a front convex portion designed to be provided at an area including a body fluid expelling portion of a wearer,
a rear convex portion designed to be provided at an area including an intergluteal cleft of the wearer, and
a constricted convex portion provided at an area connecting the front convex portion and the rear convex portion in a front-rear direction of the absorbent article whose both side edges are constricted toward an inner side,
wherein the front convex portion is formed to be vertically long in the front-rear direction of the absorbent article, both side edges of the front convex portion being formed by linear lines extending in the front-rear direction of the absorbent article, a width of the front convex portion being the same over the entire length, the width of the front convex portion being 20 to 36 mm,
wherein the rear convex portion is designed to be provided at an area from a start position of the intergluteal cleft of the wearer at a crotch side, in a rearward direction, to a position exceeding the intergluteal cleft, an end position of the intergluteal cleft or a middle position of the intergluteal cleft, a maximum width of the rear convex portion being 20 to 36 mm, the maximum width of the rear convex portion and the width of the front convex portion being the same width, and
wherein both side edges of the constricted convex portion are formed by arc-shaped curves each having a center at outside in the width direction, an interface of the constricted convex portion with the front convex portion being provided at an area corresponding to a perineum portion of the wearer, a minimum width of the constricted convex portion being 10 to 20 mm, the length of the constricted convex portion in the front-rear direction being 45 to 75% of the length of the front convex portion in the front-rear direction.

US Pat. No. 10,391,000

TRANSPORT DEVICE AND DISPOSABLE WEARABLE ARTICLE PRODUCTION METHOD USING SAME

ZUIKO CORPORATION, Osaka...

1. A transport device for transporting an object to a surface of a sheet, comprising:a delivery roller rotatable about a first rotational axis extending in a specific direction for transporting the object while holding the object on a circumferential surface thereof; and
an intermediate transporter including a main section rotatable about a second rotational axis extending in parallel to the first rotational axis, and a holding pad mounted on the main section in such a way as to revolve about the second rotational axis according to the rotation of the main section, the holding pad receiving the object onto an outer surface of the holding pad from the circumferential surface of the delivery roller at a first revolution position where the holding pad faces the delivery roller, and delivering the object onto the sheet from the outer surface of the holding pad at a second revolution position, wherein:
the outer surface of the holding pad includes a holding region for holding the object;
the intermediate transporter includes a turning mechanism for turning the holding pad about a turning axis perpendicularly intersecting the second rotational axis in the course of the movement of the holding pad from the first revolution position to the second revolution position;
the holding region includes opposite skirt portions in a revolution direction of the holding pad each of which has at least opposite ends in the specific direction that extend along a first curve when the holding pad is at the first revolution position;
the holding region includes a second area bearing on at least part of one side portion and at least part of the other side portion in the revolution direction of the holding pad, the second area extending along a second curve, when the holding pad is at the second revolution position;
the first curve is on an arc of a circle centered on the second rotational axis in a view along the second rotational axis when the holding pad is at the first revolution position;
the second curve is on an arc of a circle centered on the second rotational axis in a view along the second rotational axis when the holding pad is at the second revolution position;
the circumferential surface of the delivery roller includes a delivery side holding region for holding the object;
the delivery side holding region includes opposite side portions in the specific direction, each of the side portions having at least opposite ends in a rotational direction of the delivery roller, each end being formed with a first recess extending radially inward of the delivery roller, the first recess having a bottom surface whose intersecting line of a plane passing through the first rotational axis and the second rotational axis extends along the arc of the first curve in a view along the revolution direction of the holding pad, when the delivery side holding region and the holding region of the holding pad face each other.

US Pat. No. 10,390,999

METHOD AND APPARATUS FOR MANUFACTURING AN ABSORBENT ARTICLE INCLUDING A DISCRETE SUBSTRATE HAVING A RUGOSITY

1. A method for forming a substrate comprising a discrete substrate including a rugosity, the method comprising the steps of:providing a folding roll comprising a folding member and an outer circumferential surface extending between a first roll surface and a second roll surface, wherein at least one of the first roll surface and the second roll surface comprise an external vacuum portion, and wherein the folding member comprises a leading edge portion, a trailing edge portion opposite the leading edge portion, a groove portion between the leading edge portion and the trailing edge portion and a plurality of apertures disposed on at least one of the leading edge portion, the trailing edge portion, and the groove portion, and wherein the plurality of apertures are fluidly connected to the external vacuum portion;
advancing a discrete substrate comprising a leading edge portion, a trailing edge portion opposite the leading edge portion, and a central portion between the leading edge portion and the trailing edge portion;
associating the leading edge portion of the discrete substrate with the leading edge portion of the folding member by activating a first vacuum port of the external vacuum portion;
associating the central portion of the discrete substrate with the groove portion of the folding member by activating a second vacuum port of the external vacuum portion, wherein the central portion folds down into the groove portion;
associating the trailing portion of the discrete substrate with the trailing portion of the folding member by activating a third vacuum port of the external vacuum portion;
advancing a substrate comprising a first substrate surface and a second substrate surface opposite the first substrate surface; and
bonding the discrete substrate to at least one of the first substrate surface and the second substrate surface, wherein the discrete substrate bonded to the substrate forms a rugosity, wherein the groove portion is taken the same shape as the rugosity, and
wherein the first, second, and third vacuum port are activated sequentially, wherein the folding member is removably associated with the folding roll.

US Pat. No. 10,390,998

PROCESS AND APPARATUS FOR MANUFACTURING AN ABSORBENT ARTICLE USING A LASER SOURCE

1. A method for manufacturing an absorbent article, the method comprising:advancing a discrete component on a carrier member;
rotating a transfer member about a first axis of rotation;
accepting the discrete article on the transfer member;
advancing a first substrate, a second substrate, and one or more elastic strands toward a process member;
receiving the second substrate on an outer circumferential surface of the process member, wherein the process member rotates about a longitudinal axis of rotation;
attaching at least a portion of the one or more elastic strands to the first substrate;
disposing the second substrate on at least a portion of the one or more elastic strands and the first substrate to form a belt assembly;
advancing the belt assembly to a first laser source, where the first laser source imparts a line of weakness on the belt assembly;
advancing the belt assembly including the discrete component to a trim removal apparatus, wherein the trim removal apparatus removes trim from the line of weakness forming a separation edge;
advancing the belt assembly to a second laser source, wherein the second laser source severs a portion of the one or more elastic strands forming a gap in the elastic strands at an elastic gap location that is spaced apart from the line of weakness; and
positioning the discrete component on a portion of the belt assembly.

US Pat. No. 10,390,997

MEDICINAL PRODUCT FOR THE CARE OF AN INDIVIDUAL

1. A medicinal product for care of an individual having an injury with a surface area, comprising:a carrier;
a first functional surface on said carrier configured to cover an area adjacent to the injury;
first stem parts projecting from said first functional surface and having free front-side ends forming adhesion parts adhereable on the individual or a second functional surface primarily by van der Waals forces;
a functional care surface on said carrier configured to be adhered on the surface area of the injury; and
second stem parts projecting from said functional care surface and having free front-side ends forming adhesion parts adhereable to the surface area of the injury primarily by van der Waals forces.

US Pat. No. 10,390,995

SHORT PULSE LASER WITH ADJUSTABLE PULSE LENGTH

AMO Development, LLC, Sa...

1. A method for generating a pulse laser beam to be delivered to a patient's eye, comprising:generating a beam of laser pulses by an oscillator, the laser pulses having a first pulse length;
inputting the beam of laser pulses to a compressor;
changing the pulse length of the input laser pulses by the compressor to output a beam of laser pulses having a second pulse length, the compressor comprising a plurality of optical components directing the beam of laser pulses along a beam path, including a moveable optical component mounted on a computer controlled stage, the moveable optical component being at a first position;
focusing the beam of laser pulses having the second pulse length into a first tissue of the patient's eye to perform incisions in the first tissue;
then, receiving a user instruction by a computing device, the user instruction specifying a third pulse length;
in response to the user instruction, controlling the stage by the computing device to reposition the moveable optical component to a second position to output a beam of laser pulses having the third pulse length from the compressor; and
focusing the beam of laser pulses having the third pulse length to a second tissue of the patient's eye to perform incisions in the second tissue, wherein the third pulse length is different from the second pulse length and the second tissue is different from the first tissue.

US Pat. No. 10,390,994

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Carl Zeiss Meditec AG, J...

1. A treatment apparatus for ophthalmic surgery of an eye of a patient, said apparatus comprising:a laser device including a laser source emitting pulsed treatment laser radiation;
a focusing device that focuses the treatment laser radiation to a focus position located in the eye;
a scanner that shifts the focus position and
a control device operably coupled to the scanner and configured to control the scanner by specifying a pattern of target points located within the eye such that a cut is generated within the eye,
wherein the control device is further configured to introduce a point of aim in form of a pre-offset for at least some of the specified target points which point of aim differs from a desired final focus position by a spatial difference selected to compensate for focus position errors generated by the focusing device, and
wherein the spatial difference depends on a position of a respective target point.

US Pat. No. 10,390,993

DELIVERY SYSTEM AND METHOD OF USE FOR THE EYE

IVANTIS, INC., Irvine, C...

1. A method of maintaining an opening in a trabecular meshwork of a patient's eye to conduct fluid from an anterior chamber into Schlemm's canal of the eye, the method comprising:advancing an inserter device from the anterior chamber into the trabecular meshwork;
advancing a shaft distally within the inserter device against an implant within the inserter;
advancing the implant distally through an opening in a distal end of the inserter device;
pushing the distal end of the implant into and through the inner wall of Schlemm's canal to establish a passageway extending in a straight line from a proximal opening of the implant to a distal opening of the implant; and
conducting fluid from the anterior chamber through the implant into Schlemm's canal.

US Pat. No. 10,390,991

MEDICAL DEVICES INCORPORATING THERMOELECTRIC TRANSDUCER AND CONTROLLER

SCION NEUROSTIM, LLC, Ra...

1. A temperature control system comprising:a thermoelectric device;
a controller electrically coupled to the thermoelectric device and configured to sense an electrical characteristic of the thermoelectric device;
a heat transfer structure thermally coupled to a first side of the thermoelectric device;
a temperature controlled medium thermally coupled to a second side of the thermoelectric device so that the thermoelectric device is thermally coupled between the heat transfer structure and the temperature controlled medium, wherein said temperature controlled medium comprises a medical instrument configured to contact living tissue; and
a temperature feedback sensor, wherein said controller is configured to generate a first electrical control signal to activate said thermoelectric device and said first electrical control signal is generated in response to a first value of the electrical characteristic of the thermoelectric device, wherein the electrical characteristic of the thermoelectric device comprises an electrical characteristic of the thermoelectric device indicating one of a temperature gradient across the thermoelectric device and a temperature of the temperature controlled medium.

US Pat. No. 10,390,990

MANDIBULAR PROTRUSION DEVICE

Panthera Dental Inc., Qu...

1. A mandibular protrusion device comprising:a maxillary dental tray having a wall defining a dentition receiving cavity, the wall having an outer side;
a mandibular dental tray having a wall defining a dentition receiving cavity, the wall having an outer side; and
at least two lateral links each having an elongated portion with an anterior end, a posterior end opposed to the anterior end, a first side face and a second side face opposed to the first side face, the anterior end of each one of the at least two lateral links being removably engageable with the maxillary dental tray and the posterior end of each one of the at least two lateral links being removably engageable with the mandibular dental tray with the first side face of the elongated portion of the at least two lateral links facing the outer side of the wall of at least one of the maxillary and mandibular dental trays, the maxillary dental tray and the mandibular dental tray including female members and each one of the at least two lateral links including two male members protruding from the elongated portion with a first one of the male members protruding from the first side face of the elongated portion adjacent to the anterior end to engage the maxillary dental tray from the first side face and a second one of the male members protruding from the second side face of the elongated portion adjacent to the posterior end, to engage the mandibular dental tray from the second side face, the male members being complementary in shape with the female members and configured to be engageable and disengageable from one another in at least one engagement/disengagement configuration that is not reached when the device is worn or in normal use, the at least one engagement/disengagement configuration being reached by rotating one of the maxillary dental tray and the mandibular dental tray more than 90° with respect to a configuration where the maxillary dental tray and the mandibular dental tray are superposed.

US Pat. No. 10,390,989

APPARATUS AND METHODS FOR RECEIVING DISCHARGED URINE

PUREWICK CORPORATION, Sp...

7. An apparatus comprising:a fluid permeable support disposed between a fluid permeable membrane and fluid reservoir wherein the fluid permeable support is distinct from and at least proximate to the fluid reservoir;
a fluid outlet;
a fluid impermeable layer disposed over at least a portion of the fluid permeable support and over at least a portion of the fluid permeable membrane, the fluid impermeable layer including the fluid reservoir at a first end thereof,
the fluid impermeable layer defining a fluid impermeable casing,
the fluid permeable support being disposed within the fluid impermeable casing,
the fluid impermeable layer defining a longitudinally elongated opening, the fluid permeable membrane extending across the longitudinally elongated opening,
the apparatus configured to be disposed with the longitudinally elongated opening, and a portion of the fluid permeable membrane, adjacent to a urethral opening of a user, to receive urine discharged from the urethral opening through the fluid permeable membrane, the fluid permeable support, and into the fluid reservoir, and to have the received urine withdrawn from the fluid reservoir via the fluid outlet,
the fluid impermeable layer including a vacuum relief opening therethrough spaced from the longitudinally elongated opening and arranged to provide a flow path for air in the event that the skin of the user occludes the longitudinally elongated opening.

US Pat. No. 10,390,988

ABSORBING SEALING DEVICE FOR AN INTESTINAL STOMA

1. An ostomy accessory for an intestinal stoma of a mammal ostomy patient, adapted to be used together with an implanted constriction device with an artificial closing sphincter for independently from the ostomy accessory constricting the intestine from outside of the intestine for closing the intestinal passageway thereby hindering fecal matter to reach the ostomy accessory,wherein said ostomy accessory is adapted to work independently from the artificial closing sphincter and adapted to work in an intestinal environment where the artificial closing sphincter is preventing feces to reach the ostomy accessory, wherein said ostomy accessory is adapted to have its function consisting of to absorb non-fecal secret from the mucosa wall of the part of the intestine which is distal to the constriction device, the ostomy accessory comprising an insertion portion adapted for insertion into said intestinal stoma, said insertion portion comprising an absorbing body for absorbing and retaining liquid matter consisting of liquid secreted from a mucosa wall of the intestine, the accessory also comprising an outer part attached to the insertion portion and adapted to seal said stoma together with the insertion portion, the outer part being attached to a liquid non-permeable layer in order to allow the absorbing body to retain absorbed liquid secretions from the mucosa wall so that the mucosa wall does not dehydrate, and wherein said outer part is attached to an attachment layer adapted to create an electrostatic field between the outer part and the abdominal wall, adapted for retaining the outer part against the abdominal wall when non-fecal secret only is absorbed from the intestinal wall, wherein the insertion portion is attached to the outer part so that a portion of the outer part forms an outer wall of the insertion portion, wherein the insertion portion and the outer part are formed in one piece, without previously-separate coupled together pieces.

US Pat. No. 10,390,986

CONTROL DEVICE FOR CONTROLLING A RIGIDITY OF AN ORTHOSIS AND METHOD OF CONTROLLING A RIGIDITY OF AN ORTHOSIS

INTERNATIONAL BUSINESS MA...

1. A control device for controlling a rigidity of an orthosis, comprising:a sensing circuit for sensing a falling motion;
a signal generating circuit which generates a sensing signal based on the sensing of the falling motion; and
a rigidity control mechanism which increases a rigidity of the orthosis based on:
history data associated with a subject that is wearing the orthosis, the history data including a cognitive state of the subject and a fall history of the subject; and
the sensing signal indicating the sensing of the falling motion,
wherein the rigidity control mechanism comprises a location detecting circuit which detects a location of the orthosis, and controls the rigidity based on:
a level of risk of falling at the detected location; and
a severity of consequences of falling at the detected location.

US Pat. No. 10,390,985

BARIATRIC CLAMP WITH SUTURE PORTIONS, MAGNETIC INSERTS AND CURVATURE

ADVANCED BARIATRIC TECHNO...

1. A bariatric clamp comprising:a first elongated portion having a first proximal end and a first distal end opposite the first proximal end and comprising a first substrate member and a first polymer portion at least partially surrounding the first substrate member;
a second elongated portion having a second proximal end and a second distal end opposite the second proximal end and comprising a second substrate member and a second polymer portion at least partially surrounding the second substrate member; and
a bight portion comprising a third polymer portion forming a flexible hinge joining the first elongated portion at the first proximal end thereof and joining the second elongated portion at the second proximal end thereof;
wherein at least a portion of at least one of the first elongated portion and the second elongated portion is bent at least one of toward and away from the other of the first elongated portion and the second elongated portion at an intermediate point between the respective proximal end and the respective distal end of the elongated portion that is bent, and
wherein the intermediate point is nearer the other of the first elongated portion and the second elongated portion than at least one of the proximal end of the elongated portion that is bent and the distal end of the elongated portion that is bent is.

US Pat. No. 10,390,984

GASTRIC DEVICES, SYSTEMS, AND METHODS

CVDevices, LLC, San Dieg...

1. An implantable restraining device, comprising:a first engaging component and a second engaging component each defining a longitudinal axis, each configured for laparoscopic insertion into a body cavity, and each comprising a proximal end, a distal end, and a body extending therebetween, wherein the body of the first engaging component is configured to conform to a first targeted tissue surface, and the body of the second engaging component is configured to conform to a second targeted tissue surface;
a first swivel arm and a second swivel arm, each defining a length and connected to the first engaging component and the second engaging component, having a first position wherein the lengths are substantially coaxial with the longitudinal axes of the first engaging component and the second engaging component and rotatable to a second position wherein the lengths are substantially perpendicular to the longitudinal axes of the first engaging component and the second engaging component;
wherein the first swivel arm and the second swivel arm are both connected to both the first engaging component and the second engaging component in both the first position and the second position; and
wherein the first engagement component and the second engagement component are planar.

US Pat. No. 10,390,983

MEDICAL-DEVICE POSITION ADJUSTING METHOD AND MEDICAL DEVICE SYSTEM

TERUMO KABUSHIKI KAISHA, ...

1. A medical-device position adjusting method comprising:a. providing a medical device that is configured to be delivered to a lesion area in a body lumen, a guide wire that is configured to guide the medical device, a port member that is configured to introduce the guide wire and the medical device into a living body, a proximal-end fixing member that is configured to fix the guide wire and the port member and is provided with an operation unit that is configured to cause the guide wire to move in an insertion or pulling-out direction, an anchor device provided with an anchor portion in a distal portion thereof, and an anchor-device guide wire that is configured to guide the anchor device;
b. inserting the guide wire through the port member into the body lumen to extend to a distal side of the lesion area relative to the port member;
c. inserting the anchor device into the body lumen and fixing the guide wire to an inner wall surface of the body lumen by the anchor portion on the distal side of the lesion area;
d. inserting the medical device from the port member along the guide wire to the lesion area or a vicinity of the lesion area;
e. fixing the guide wire and the port member with the proximal-end fixing member; and
f. causing the guide wire to move in the insertion or pulling-out direction by using the operation unit to change a path of the guide wire in the body lumen and adjust a position of the medical device in the lesion area.

US Pat. No. 10,390,981

IMPLANT DELIVERY DEVICE ADAPTED TO BE ATTACHED TO OR INTERCONNECTED WITH A CATHETER, CATHETER AND METHOD

Venus Medtech (Hangzhou) ...

1. An assembly having an inner space extending along a longitudinal direction thereof, the assembly comprising:a device including a lumen;
an implant attached to the device, wherein the implant comprises a heart valve;
a first folding means connected to the implant and adapted for folding or unfolding the implant, the first holding means having an end;
a second folding means having an end that is coupled to the end of the first folding means; and
a catheter detachably attached to or interconnected with the device via a snap-on connection, the catheter including a lumen,
wherein the inner space includes a first section and a second section next to the first section along the longitudinal direction of the assembly, the first section being defined by the lumen of the device and the second section being defined by the lumen of the catheter, and
wherein the first folding means extends at least partially in the first section of the inner space, and the second folding means extends at least partially in the second section of the inner space.

US Pat. No. 10,390,980

EXTRALUMINAL ENTEROGENESIS DEVICE

1. A medical device, comprising:an extraluminal displacement mechanism comprising:
a first length as measured along a longitudinal axis between two attachment points prior to activation of the extraluminal displacement mechanism;
a self-activated shape memory polymer system comprising isobornyl acrylate, HEA, and HDDA, wherein:
the extraluminal displacement mechanism is configured to:
connect outside an intestinal lumen of a patient between the two attachment points on the lumen;
create automatically a displacement distance between the two attachment points via actuation of the extraluminal displacement mechanism before a first defined time elapses while the extraluminal displacement mechanism is exposed to a first exposure environment of two different exposure environments;
create automatically the displacement distance between the two attachment points via actuation of the extraluminal displacement mechanism only after a second defined time while the extraluminal displacement mechanism is exposed to a second exposure environment of the two different exposure environments;
the extraluminal displacement mechanism has a second length as measured along the longitudinal axis after activation of the extraluminal displacement mechanism;
the second length is greater than the first length;
the extraluminal displacement mechanism exerts force on at least one of the two attachment points as it expands from the first length to the second length;
the self-activated shape memory polymer system is further configured to be activated solely via a first exposure to a 37 degrees Celsius physiological saline fluid and regulated for that first exposure to induce an early activation transition that occurs within the first defined time of no greater than 168 hours of exposure; and
the self-activated shape memory polymer system is further configured to be activated solely by second exposure to 37 degrees Celsius air at atmospheric pressure and relative humidity between 50 and 60 percent and regulated for that second exposure to induce a late activation transition that occurs only after the second defined time of greater than 500 hours of exposure.

US Pat. No. 10,390,979

MANUFACTURING PROCESS FOR POLYMERIC STENTS

Advanced Cardiovascular S...

1. A method of fabricating a stent comprising:forming a polymer tube made of a biodegradable polymer,
wherein forming the polymer tube comprises forming an extruded polymer tube and quenching the extruded polymer tube from a first temperature, the first temperature being above a melting temperature of the biodegradable polymer, to a second temperature, the second temperature being below a glass transition temperature of the biodegradable polymer, such that the biodegradable polymer of the formed tube is an amorphous or substantially amorphous glassy polymer;
processing the tube to increase the crystallinity of the biodegradable polymer from amorphous or substantially amorphous to between 35% and 55%;
cutting a pattern in the processed tube to form a cylindrically-shaped scaffold, wherein the scaffold includes a pattern of interconnecting struts,
wherein the pattern comprises a plurality of cylindrical rings of struts and longitudinal linking struts connecting the rings,
wherein the rings include bending elements including struts that flex inward to allow crimping of the scaffold and flex outward to allow expansion of the scaffold,
wherein the scaffold is radially expandable in a blood vessel of a body and has adequate radial strength to hold open the blood vessel, and
wherein the stent comprises the scaffold.

US Pat. No. 10,390,978

HIGHLY FLEXIBLE STENT AND METHOD OF MANUFACTURE

1. An implantable prosthesis comprising:a continuous helical winding having a plurality of circumferential sections circumscribing a helical axis, which is cut by an orthogonal plane, from a first end to a second end to define a tube, the plurality of circumferential sections being spaced apart along the helical axis, each of the plurality of circumferential sections having a non-orthogonal helical angle relative to the helical axis;
at least one bridge configured to connect one circumferential section to an axially-spaced adjacent circumferential section, the at least one bridge extending along its entire length on a plane orthogonal to the helical axis;
at least one annular ring connected to one of the first and second ends of the continuous helical winding, the at least one annular ring orthogonal to the helical axis; and
at least one marker having a first end connected to the at least one annular ring, and a second end connected to the continuous helical winding,
wherein the implantable prosthesis is operable from a contracted state to an expanded state and in the contracted state the at least one bridge creates a circumferential offset between adjacent circumferential sections that when measured in the plane orthogonal to the helical axis is equal to the length of the at least one bridge and in the expanded state the at least one bridge maintains the circumferential off-set.

US Pat. No. 10,390,977

ENDOVASCULAR IMPLANT

Intact Vascular, Inc., W...

1. A self-expanding intravascular implant comprising:a proximal undulating ring on a proximal side of the intravascular implant comprising a plurality of proximal struts, the plurality of proximal struts comprising a plurality of first proximal struts and a plurality of second proximal struts, wherein each first proximal strut of the plurality of first proximal struts is connected to at least one second proximal strut of the plurality of second proximal struts, wherein a proximal end of each first proximal strut of the plurality of first proximal struts is connected to a proximal end of a second proximal strut of the plurality of second proximal struts to form a plurality of first proximal apices and a distal end of each first proximal strut of the plurality of first proximal struts is connected to a distal end of a second proximal strut of the plurality of second proximal struts to form a plurality of first distal apices, wherein at least one first proximal apex of the plurality of first proximal apices defines a proximal end of the intravascular implant;
a distal undulating ring on a distal side of the intravascular implant comprising a plurality of distal struts, the plurality of distal struts comprising a plurality of first distal struts and a plurality of second distal struts, wherein each first distal strut of the plurality of first distal struts is connected to at least one second distal strut of the plurality of second distal struts, wherein a distal end of each first distal strut of the plurality of first distal struts is connected to a distal end of a second distal strut of the plurality of second distal struts to form a plurality of second distal apices and a proximal end of each first distal strut of the plurality of first distal struts is connected to a proximal end of a second distal strut of the plurality of second distal struts to form a plurality of second proximal apices, wherein at least one second distal apex of the plurality of second distal apices defines a distal end of the intravascular implant;
a plurality of bridge members each located between the proximal undulating ring and the distal undulating ring and each connecting one first distal apex of the plurality of first distal apices to one second proximal apex of the plurality of second proximal apices;
wherein the intravascular implant has a compression force curve being a measure of the amount of radial compression force required to compress the intravascular implant along a range of outer diameters, and has an expansion force curve being a measure of the amount of radial expansion force exerted by the intravascular implant when the intravascular implant self-expands along the range of outer diameters, wherein the range of outer diameters is at least about 2 mm and a change in radial force along the expansion force curve is no more than about 3 Newtons (N) along the range of outer diameters.

US Pat. No. 10,390,976

LINER FOR ORTHOPEDIC OR PROSTHETIC DEVICE

OSSUR ICELAND EHF, Reyja...

1. A liner for an orthopedic device, comprising:a core formed from a porous and compressible open-celled polyurethane foam, the core having first and second surfaces;
a first layer formed from an aqueous-based polyurethane emulsion and located along the first surface of the core;
a second layer formed from a hook receivable material and has a first surface located directly adjacent to the second surface of the core;
a polymeric film extending over a second surface of the second layer opposite the first surface of the second layer;
wherein the core has greater rigidity than the first layer, both the core and the first layer are arranged for transfer of air and vapor through a combined thickness;
wherein the polymeric film defines at least one opening exposing the second layer.

US Pat. No. 10,390,975

TRANSCUTANEOUS IMPLANT FOR SKELETAL ATTACHMENT OF EXTERNAL PROSTHETIC DEVICES

Zimmer, Inc., Warsaw, IN...

1. A transcutaneous device to anchor an external prosthetic device to a bone, the transcutaneous device comprising:a bone anchor implantable into bone and including a male end configured to extend from the bone, wherein the male end has a threaded passage for receiving a fastener, the passage configured to extend along a longitudinal length of the male end external to the bone;
a prosthetic interface configured for implantation external to the bone and configured for soft tissue ingrowth and vascularization after implantation, the prosthetic interface having a male connection configured to extend external to the soft tissue and configured to mate with the external prosthetic device, the prosthetic interface having a female connection configured to receive the male end of the bone anchor therein, wherein the prosthetic interface has a through bore that extends longitudinally from the male connection to the female connection, and wherein the threaded passage and the through bore are substantially aligned to receive the fastener to couple the prosthetic interface to the bone anchor when the male end of the bone anchor is received in the female connection of the prosthetic interface; and
a failsafe comprising a proximal portion and a distal portion, the proximal portion couplable to the prosthetic interface external to the bone and the soft tissue at a proximal end, and couplable to the external prosthetic device at a distal end, wherein the failsafe includes a shear pin connecting the proximal portion and the distal portion, the shear pin configured to separate the proximal portion from the distal portion to separate the prosthetic device from the prosthetic interface when a predetermined shear load is applied to the failsafe, wherein a shaft of the failsafe includes a medial/lateral bending notch configured to separate the prosthetic device from the prosthetic interface when a predetermined medial/lateral bending load is applied to at least one of the proximal portion and the distal portion, and wherein the failsafe includes an anterior/posterior bending notch configured to separate the prosthetic device from the prosthetic interface when a predetermined anterior/posterior bending load is applied to the failsafe.

US Pat. No. 10,390,974

PROSTHETIC FOOT WITH REMOVABLE FLEXIBLE MEMBERS

1. A prosthetic foot comprising:an attachment member comprising a connector configured to connect the attachment member to a user or another prosthetic device;
at least one first brace mounted to the attachment member;
at least one first flexible member connected to the attachment member by the at least one first brace such that the first brace mounts around the first flexible member and a force between the ground and the attachment member can be supported by the at least one first flexible member;
an unpowered actuator mounted to the attachment member;
at least one second brace mounted to the actuator; and
at least one second flexible member connected to the attachment member by the at least one second brace such that the second brace mounts around the second flexible member and a force between the ground and the attachment member can be supported by the at least one second flexible member,
wherein at least one of the combination of the first brace and the first flexible member and the combination of the second brace and the second flexible member form a non-rotating joint between each other,
wherein the at least one first brace attaches to the attachment member by a rotatable joint, such that the first brace rotates relative to the attachment member about a single pivot.

US Pat. No. 10,390,973

INTERACTIVE EXOSKELETON ROBOTIC KNEE SYSTEM

THE HONG KONG POLYTECHNIC...

1. An interactive exoskeleton knee system comprising:an exoskeleton framework having a thigh support, a shank support, a thigh mechanical support and a shank mechanical support;
at least one motion sensor mounted on the exoskeleton framework;
at least one force sensor attached on a foot piece or inside of a shoe;
a motor for rotating the shank mechanical support from the thigh mechanical support to generate an assistant power for a knee joint;
a mechanical lock system connected the thigh mechanical support and the shank mechanical support to provide mechanical support;
a control box connected with the at least one motion sensor and the at least one force sensor for providing power and signal communication, and sending control command to the motor and the mechanical lock system; and
a control algorithm, executed by the control box, for using collected data from the at least one motion sensor and the at least one force sensor to identify a walking environment based on a gait analysis, and for driving the knee joint by the motor and locking the knee joint by the mechanical lock system according to a gait pattern based on the walking environment;
wherein the at least one motion sensor comprises a gyroscope and an accelerometer, and the control algorithm is further for using data detected by the at least one motion sensor for identifying a walking speed; and
wherein the control algorithm is further used for identifying the walking speed when a loading force detected by the at least one force sensor drops below a loading force threshold, an angular velocity detected by the gyroscope is larger than an angular velocity threshold, and an acceleration detected by the accelerometer is larger than an acceleration threshold, and classifying the walking environment.

US Pat. No. 10,390,971

CYLINDER HEAD, ELEMENT AND FLANGE OF A PISTON ENGINE

MECACHROME FRANCE, Amboi...

1. A longitudinal piston-engine cylinder head, comprising:a cylinder head body and a base plate, the base plate comprising at least one element that extends entirely within a plane, the base plate being interposed between a combustion chamber and the cylinder head body,
wherein the base plate comprising an upper face facing the cylinder head body and an opposing lower face arranged to face the combustion chamber, the base plate being attached to the cylinder head body, the cylinder head body being made of a material with mass density and hardness values that are lower than the mass density and hardness values of a material used to make the base plate,
wherein the base plate and the cylinder head body are assembled with screws used to fasten the base plate to the cylinder head body that are located towards the periphery of the base plate and of the cylinder head body and at least one part used to fasten the cylinder head body to the base plate comprising a threaded end engaged in a corresponding orifice of the base plate, said corresponding orifice being located closer to a center of the base plate than the screws,
wherein the base plate or each of at least one element of the base plate includes an internal cooling circuit to circulate a heat-transfer fluid, said internal cooling circuit having at least one fluid inlet, a fluid circulation channel and several fluid drainage channels, the several fluid drainage channels forming an angle greater than 20° with the plane of the base plate passing around gas exhaust ducts of the cylinder head body and wherein the fluid circulation channel, extending along a path, has an average width that is less than 20% of a transverse dimension of the base plate and includes, along said path, at least one narrowing of the path extending over at least 2.5% of a length of the path and an average width of at least one narrowing of the path parallel to the plane of the base plate is less than 10% of a width of the base plate.

US Pat. No. 10,390,970

ORTHOPAEDIC SURGICAL SAW ASSEMBLY FOR REMOVING AN IMPLANTED GLENOID COMPONENT AND METHOD OF USING THE SAME

DEPUY SYNTHES PRODUCTS, I...

1. A surgical instrument for removing an implanted glenoid component from the glenoid of a patient, comprising:a protective dual-lumen cannula having a first cannula and a second cannula positioned adjacent to the first cannula, each of the first cannula and the second cannula having a proximal end, a distal end, and an elbow positioned adjacent to each of the distal ends, and
a flexible wire saw having a first wire section including a first end, a second section including a second end opposite the first end, and a middle section positioned between the first end and the second end, wherein each of the elbows is configured to redirect the wire saw from a first orientation to a second orientation for cutting through the glenoid component, wherein, in the first orientation, the first wire section and the second wire section of the wire saw extend substantially coplanar to a plane defined by the first cannula and the second cannula of the protective dual-lumen cannula, and, in the second orientation, the middle section of the wire saw is angled out of the plane, and
wherein the first end of the flexible wire saw extends out of the proximal end of the first cannula, the second end of the flexible wire saw extends out of the proximal end of the second cannula, and the middle section of the flexible wire saw forms a loop that extends outwardly in the second orientation from the distal end and the elbow of the first cannula and outwardly in the second orientation from the distal end and the elbow of the second cannula such that the middle section of the flexible wire saw is exposed to cut the glenoid component.

US Pat. No. 10,390,969

BI-DIRECTIONAL FIXATING TRANSVERTEBRAL BODY SCREWS AND POSTERIOR CERVICAL AND LUMBAR INTERARTICULATING JOINT CALIBRATED STAPLING DEVICES FOR SPINAL FUSION

Moskowitz Family LLC, Ro...

1. A system to provide fusion of a first vertebral body to a second vertebral body via biological bone fusion and screw fusion, the system comprising:an intervertebral cage comprising a top portion and a bottom portion wherein the top portion comprises first and second projections that extend outward in opposite directions to engage slots defined in the bottom portion so as to operably connect the top portion to the bottom portion, wherein the top portion and the bottom portion combine to form a top wall, a bottom wall, a first sidewall and a second sidewall, wherein the top wall is formed at least partially by the top portion and wherein the first sidewall, the second sidewall, and the bottom wall are formed at least partially by the bottom portion, and wherein the intervertebral cage defines:
at least one open space capable of receiving bone filling for biological bone fusion,
a first internal screw guide having a first entry opening and a first exit opening, the first entry opening formed in a top surface of the top portion at the top wall and the first exit opening formed at least partially in a bottom surface of the top portion at the top wall and at least partially in a first side surface of the top portion at the top wall,
a second internal screw guide having a second entry opening and a second exit opening, the second entry opening formed in the top surface of the top portion at the top wall and the second exit opening formed at least partially in the bottom surface of the top portion at the top wall and at least partially in a second side surface of the top portion at the top wall, wherein the first internal screw guide and the second internal screw guide are angled to orient screw members bi-directionally,
an indentation extending into the top surface of the top portion between the first internal screw guide and the second internal screw guide at an angle that is substantially perpendicular to the top surface, wherein the indentation is defined by first and second parallel indentation sides and third and fourth parallel indentation sides that are perpendicular to the first and second parallel indentation sides, and wherein the indentation is positioned along a centerline axis of the intervertebral cage that bisects the top surface, and
a circular top hole extending into the top surface of the top portion between the first internal screw guide and the second internal screw guide at an angle that is substantially perpendicular to the top surface, wherein the circular top hole is positioned along the centerline axis of the intervertebral cage that bisects the top surface;
a first screw having a first screw head defining a first head indentation shaped for receiving a tool and a first threaded body that is sized and configured to be inserted through the first internal screw guide at a first angle so the first screw extends from the intervertebral cage into a first vertebral body adjacent the intervertebral cage when inserted in a disc space; and
a second screw having a second screw head defining a second head indentation shaped for receiving the tool and a second threaded body that is sized and configured to be inserted through the second internal screw guide at a second angle different than the first angle so the first screw extends from the intervertebral cage into a second vertebral body adjacent the intervertebral cage when inserted in the disc space.

US Pat. No. 10,390,968

DEVICE FOR SPINAL SURGERY, CORRESPONDING GUIDE SLEEVE AND KIT WITH GUIDE SLEEVE

JOIMAX GMBH, Karlsruhe (...

1. A guide sleeve, for spinal surgery that forms a part of a kit, the guide sleeve comprising a non-cylindrical jacket, the non-cylindrical jacket comprising narrow sides and two broad sides, the two broad sides being opposite each other, the two broad sides having a width greater than a width of the narrow sides, one of the broad sides being flat, another one of the broad sides being convexly bent outwards, wherein a radius of curvature of a transition between one of the broad sides and one of the narrow sides is between 3 mm and 4.5 mm.

US Pat. No. 10,390,967

INSERTER GUIDE AND DRIVER SYSTEM

DePuy Synthes Products, I...

1. A driver comprising:a rotatable driver shaft;
a rod disposed within the rotatable driver shaft;
a driver tip at a distal end of the rotatable driver shaft, the driver tip coupled to the rotatable driver shaft at a rotatable joint;
a housing that receives the rotatable driver shaft at a distal end thereof;
a mating sleeve coupling the driver shaft to the housing, the mating sleeve fixedly coupled to a proximal end of the driver shaft, the driver shaft extending into a central channel of the mating sleeve, the proximal end of the driver shaft not extending beyond a proximal end of the mating sleeve; and
a control element disposed at a proximal end of the housing, the control element receiving a proximal end of the rod,
wherein the housing, driver tip and driver shaft are coupled such that an input force received at the housing results in a corresponding force at the driver tip,
wherein actuation of the control element engages the proximal end of the rod, causing a distal end of the rod to frictionally engage the rotatable joint and prevent movement between the rod and the driver tip and hold the driver tip at the adjusted angle.

US Pat. No. 10,390,966

SYSTEM INCLUDING FEMORAL AUGMENT TRIALS AND METHOD OF PERFORMING AN ORTHOPAEDIC JOINT REPLACEMENT PROCEDURE

DePuy Ireland Unlimited C...

14. An orthopaedic surgical system comprising:a femoral trial component configured to be coupled to a surgically-prepared distal end of a patient's femur, the femoral trial component comprising an anterior flange, and a pair of curved arms extending away from the anterior flange,
a plurality of augment trial components, each augment trial component including a peg and a magnet, and
wherein each curved arm includes an aperture defined in a bone-facing surface that is sized to receive the peg of one of the plurality of augment trial components,
wherein each augment trial component has a different thickness, and
the curved arms of the femoral trial component include a plurality of cutting slots, each cutting slot being spaced apart from the bone-facing surface by a distance equal to the thickness of one of the augment trial components.

US Pat. No. 10,390,965

SYSTEM FOR PREPARING A PATIENT'S FEMUR IN AN ORTHOPAEDIC JOINT REPLACEMENT PROCEDURE

DePuy Ireland Unlimited C...

1. An orthopaedic surgical system comprising:a tibial base plate sized to be positioned on a proximal surface of a patient's tibia, and
an insert trial component configured to be attached to the tibial base plate, the insert trial component including a pair of proximal curved concave surfaces,
a femoral trial component configured to be coupled to a distal end of a patient's femur, the femoral trial component comprising an anterior flange, and a pair of curved arms extending away from the anterior flange, each arm including a curved condyle surface and a plurality of cutting guide slots, and
a femoral trial insert component including a central body sized to be positioned between the pair of curved arms and a pair of mounting flanges extending outwardly from the central body, each mounting flange including a distal surface and a fastener retained in each mounting flange to secure the mounting flange to the femoral trial component,
wherein the femoral trial component includes a pair of slots in the curved arms sized to receive the mounting flanges of the femoral trial insert component,
wherein the distal surfaces and the curved condyle surfaces are configured to engage and articulate on the proximal curved concave surfaces of the insert trial component when the femoral trial insert component is secured to the femoral trial component, and
wherein each fastener includes an elongated threaded shaft sized to engage a threaded bore defined in one of the mounting flanges of the femoral trial insert component, a head connected to the elongated threaded shaft, a socket defined in the head, and an annular flange extending radially outward from the head to engage the mounting flange of the femoral trial insert component.

US Pat. No. 10,390,963

INTERVERTEBRAL IMPLANT

DePuy Synthes Products, I...

1. A method of implanting an expandable intervertebral implant comprising:positioning the implant between two vertebral bodies via a transforaminal approach, wherein the implant comprises:
a one-piece upper body portion;
a one-piece lower body portion that generally faces the upper body portion along a transverse direction;
a threaded shaft disposed between the upper and lower body portions, the threaded shaft having a first end and a second end spaced from the first end in a unidirectional first direction;
a first wedge member threadedly coupled to the first end of the threaded shaft, wherein the first wedge member defines respective upper and lower guide members; and
a second wedge member supported by the threaded shaft at a location spaced from the first wedge member in the unidirectional first direction that is perpendicular to the transverse direction, wherein the second wedge member defines respective upper and lower guide members,
wherein each of the upper and lower guide members of the first wedge member has respective outermost lateral ends spaced from each other along a lateral direction that is perpendicular to each of the unidirectional first direction and the transverse direction, the first wedge member has second respective outermost lateral ends that are spaced from each other along the lateral direction and coplanar with the threaded shaft in a plane that is perpendicular to the transverse direction, and the outermost ends of the upper and lower guide members of the first wedge member are inwardly recessed with respect to the second respective outermost ends along the lateral direction;
after the positioning step, rotating the threaded shaft about a shaft axis so as to increase a distance between the upper and lower body portions, wherein the rotating step causes
1) the first wedge member to threadedly move along the threaded shaft toward the second wedge member as
a) the upper guide member of the first wedge member rides in a first slot of the upper body portion and
b) the first wedge member pushes against the upper and lower body portions, and
2) the second wedge member to push against the upper and lower body portions.

US Pat. No. 10,390,962

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. A spinal system having a proximal end, a distal end, a central portion between the proximal end and the distal end, the central portion extending along a longitudinal axis of the spinal system between the proximal end and the distal end, a midpoint located midway between the proximal end and the distal end along the longitudinal axis, said spinal system comprising:a first endplate;
a second endplate;
a driving ramp positioned at the proximal end between the first endplate and the second endplate; and
a central ramp positioned at the distal end between the first endplate and the second endplate,
wherein the driving ramp comprises a first ramped portion and a second ramped portion, wherein a first angled groove is formed through the first ramped portion and a second angled groove is formed through the second ramped portion,
wherein the driving ramp includes an annular contact surface for engagement with an actuator assembly,
wherein the central ramp comprises a first expansion portion at the distal end and a rod receiving extension extending from the first expansion portion into the central portion, wherein the rod receiving extension extends to a second end of the central ramp disposed away from the distal end that is beyond the midway point towards the proximal end midway point of the longitudinal axis towards the proximal end,
wherein the rod receiving extension comprises a first central ramped portion to engage the first endplate in the central portion and a second central ramped portion to engage the second endplate in the central portion, wherein the first central ramped portion and the second central ramped portion are separated from the first expansion portion by a portion of the rod receiving extension.

US Pat. No. 10,390,961

STACKABLE INTERLOCKING INTERVERTEBRAL SUPPORT SYSTEM

NuVasive, Inc., San Dieg...

1. A spinal support system, comprising:a plurality of elongated inserts having ramped distal portions for successively increasing the height of a space within a spine, the plurality of elongated inserts including a first insert having a distal end, a proximal end, an upper surface, and a lower surface, the first insert having a maximum length extending between the distal and proximal ends and a maximum height extending between the upper and lower surfaces, the maximum length being greater than the maximum height, wherein the ramped distal portion of the first insert comprises a planar beveled surface extending between the lower surface and the upper surface, the planar beveled surface forming a tapered endwall that tapers from the lower surface to the upper surface, and where the plurality of elongated inserts further includes a second insert identical in size and shape to the first insert, wherein the second insert is positioned with at least a portion of the second insert lower surface above at least a portion of the first insert upper surface.

US Pat. No. 10,390,960

VERTEBRAL BODY REPLACEMENT

NuVasive, Inc., San Dieg...

1. An implant for providing support between a first vertebra and a second vertebra in a space remaining after the removal of at least part of one vertebra, comprising:an expandable body extending along a longitudinal axis from a first end to a second end, the expandable body having a transverse axis extending perpendicular to the longitudinal axis, a body length spanning from the first end to the second end, a central aperture spanning from the first end to the second end, and a ring member rotatable about the longitudinal axis to adjust the body length, the first end including a first end attachment feature having an outer profile and a plurality of threaded holes situated radially about the longitudinal axis;
a first endplate having a first surface opposing a second surface, said first endplate coupled to the expandable body via a first attachment feature on the first surface, the first attachment feature including a first receptacle configured to receive the outer profile of the first end and a screw opening extending through the second surface into the first receptacle, the first receptacle configured to receive the first attachment feature outer profile in a plurality of different orientations such that the first endplate is coupleable to the first end in a plurality of rotational positions relative to the transverse axis, the plurality of rotational positions comprising a first rotational position and a second rotational position, wherein the second rotational position is rotated 30 to 150 degrees from the first rotational position, with the screw opening aligning with one of the plurality of threaded holes in each of the plurality of positions and receiving a set screw therethrough to lock the first endplate in the selected position; and
a second endplate having a third surface opposing a fourth surface, said second endplate coupled to the expandable body via a second attachment feature on the third surface that mates with a second end attachment feature, said second attachment feature configured to couple with the second end attachment feature in a plurality of different orientations such that the second end plate is coupleable to the second end in a plurality of positions relative to the transverse axis.

US Pat. No. 10,390,958

ARTIFICIAL INTERVERTEBRAL DISC IMPLANT DEVICE

1. A customized, patient specific intervertebral disc replacement device configured to replace one or more intervertebral discs in a spinal column of a human or an animal to restore or provide flexibility and mobility post-operatively to at least two adjacent vertebrae, the device configured to be positioned with respect to at least one intervertebral disc space respectively located between the at least two adjacent vertebrae, the device comprising:a connector integrally formed with at least one shock absorbing pad, the connector configured to extend between and interconnect the at least two adjacent vertebrae when the at least one shock absorbing pad is located within the at least one intervertebral disc space;
wherein the at least one shock absorbing pad is made from the same material as the connector such that the at least one shock absorbing pad extends laterally from the connector, wherein the material of the connector and the at least one shock absorbing pad is continuous from side-to-side, from front-to-back and from a pad top surface to a pad bottom surface, and wherein the material of the connector and the at least one shock absorbing pad is a compressible, flexible, and resilient biocompatible material selected from the group consisting of compressible polymers, silicon-based flexible polymers, elastomers, and elasto-plastics,
wherein the at least one shock absorbing pad is configured to exhibit mechanical and functional properties similar to those of a natural biological intervertebral disc such that the at least one shock absorbing pad is configured to simulate similar mobility, operational function and normal performance of the natural biological intervertebral disc, and wherein the at least one shock absorbing pad is configured to be customized to and made specifically for an individual patient based on anatomical characteristics of the individual patient's intervertebral disc space by molding, 3D printing from digitized MRI, or other radiographic techniques, so that the at least one shock absorbing pad is configured to fill the entire at least one intervertebral disc space from side-to-side, front-to-back and top-to-bottom upon being deployed and located therein.

US Pat. No. 10,390,957

DEVICE FOR REPAIRING A HUMAN OR ANIMAL JOINT

SPINEWELDING AG, Schlier...

1. A device for treating a human or animal joint, the joint comprising two articulating surfaces and the device comprising:two articulating portions capable of at least limited articulation relative to each other and being equipped for being fixed one in each one of the articulating surfaces with the aid of a material having thermoplastic properties and vibration energy, wherein the material having thermoplastic properties is arranged on outer sides of each articulating portion,
a temporal connector portion being removably arranged between the two articulating portions, wherein the temporal connector portion, when arranged between the two articulating portions, connects the two articulating portions to form a rigid, non-articulating entity constituting one piece at least during an implantation procedure, said temporal connector portion being configured to be removed separately from said two articulating portions after having connected the two articulating portions at least for the time of the implantation procedure,
and an interface portion that is arranged between inner sides of the articulating portions, wherein the interface portion is elastic and fixed to each one of the inner sides of the two articulating portions and wherein the temporal connector portion is a spreader that is clamped between the inner sides of the articulating portions and retained in a clamped position by elasticity of the interface portion.

US Pat. No. 10,390,956

DEVICE FOR COVERING AND/OR RECONSTRUCTING A BONE DEFECT SITE, METHOD FOR PRODUCING A CAP FOR A COVER FOR A BONE DEFECT SITE

ReOss GmbH, Filderstadt ...

1. Device for a bone defect site, the device comprising:a cap comprising a rim and a first side configured to face away from the bone defect and a second side configured to face toward the bone defect,
wherein the cap comprises a dimensionally stable material, and the second side of the cap or the first side of the cap is configured to correspond to the shape of a regenerated bone,
wherein
the device has at least one positioning portion having a continuous wall configured to face a healthy bone that borders on the bone defect, the at least one positioning portion being disposed at the rim of the cap,
or
the device has at least one connector for fixation of the cap within the region of the bone defect, and the device has at least one positioning portion having a wall configured to face a healthy bone that borders on the bone defect, the at least one positioning portion being disposed at the rim of the cap.

US Pat. No. 10,390,955

BONE IMPLANTS

ENGAGE MEDICAL HOLDINGS, ...

1. A bone implant, comprising:a first bone-contacting surface;
a second bone-contacting surface opposite the first bone-contacting surface;
a proximal side;
a distal side, wherein the first bone-contacting surface and the second bone-contacting surface diverge away from each other toward the proximal side of the bone implant and converge together toward the distal side of the bone implant;
a first protrusion;
a second protrusion;
a third protrusion intermediate the first protrusion and the second protrusion;
an intermediate portion intermediate the first protrusion and the second protrusion, wherein the first protrusion and the second protrusion protrude away from the intermediate portion toward the distal side of the bone implant;
a first recess intermediate the first protrusion and the second protrusion, wherein the first recess is substantially wider than the first protrusion and the second protrusion; and
a second recess intermediate the first protrusion and the third protrusion.

US Pat. No. 10,390,954

METHOD TO INTRODUCE AN IMPLANTABLE DEVICE TO FILL A BONE VOID WHILST MINIMISING PRESSURISATION

BIOCOMPOSITES LIMITED, K...

1. A method of reconstructing a bone void in a patient, the method comprising introducing into a bone void of one or more implantable devices, each of which one or more implantable devices are substantially cylindrical, having a convex, domed or semi-spherical shaped ends; contain one or more longitudinal channels where the one or more longitudinal channels create a venting path allowing for depressurisation of any contents of the bone void, the one or more longitudinal channels each intersecting a surface of the device and extending towards an axial centerline thereof, and being tapered such that the width of the one or more longitudinal channels opening on an outer, circumferential edge of the implantable device is greater than its width at a base thereof; and have a flat surface on an opposing longitudinal side to the one or more longitudinal channels;whereby introduction of the one or more implantable devices reconstructs bone in the bone void in the patient.

US Pat. No. 10,390,953

METHODS AND DEVICES FOR REDUCING PARAVALVULAR LEAKAGE

Cardiac Dimensions Pty. L...

1. A method of reducing paravalvular leakage associated with a replacement mitral valve, comprising:monitoring for paravalvular leakage between a replacement mitral valve and tissue proximate the mitral valve annulus;
if paravalvular leakage is observed, deploying a tissue reshaping device solely within a coronary sinus;
intravascularly remodeling coronary sinus tissue with the tissue reshaping device deployed solely within the coronary sinus to cause the remodeling of at least one of mitral valve annulus tissue, at least one mitral valve leaflet, and left atrium tissue in an attempt to reduce the paravalvular leakage; and
monitoring for a reduction in paravalvular leakage after the remodeling step.

US Pat. No. 10,390,952

PROSTHETIC VALVE WITH FLEXIBLE TISSUE ANCHOR PORTIONS

CARDIOVALVE LTD., Or Yeh...

1. An expandable prosthetic valve for implantation within a native mitral valve, the prosthetic valve comprising:an expandable annular valve body;
a plurality of ventricular anchoring legs, each ventricular anchoring leg configured to extend radially outward from the expandable annular valve body to respective terminal leg ends; and
a plurality of atrial anchoring arms, each atrial anchoring arm configured to extend radially outward from the expandable annular valve body,
wherein the expandable prosthetic valve is configured to assume:
a radially compressed state in which the prosthetic valve is configured to be contained at least partially within a prosthetic valve delivery device, and
a radially expanded state in which the expandable prosthetic valve is configured to be anchored within the native mitral valve,
wherein at least one atrial anchoring arm includes:
a rigid portion,
a flexible portion including a structure with multiple curves,
a first opening situated between the structure with multiple curves and a terminal end of the at least one atrial anchoring arm, and
a second opening situated between the structure with multiple curves and a location of connection between the at least one atrial anchoring arm and the expandable annular valve body,
wherein the structure with multiple curves does not extend to the terminal end of the at least one atrial anchoring arm, and
wherein when the expandable prosthetic valve is in the radially expanded state, the at least one atrial anchoring arm is configured to be arranged such that a part of the flexible portion situated outside a circumference defined by the terminal leg ends has a greater length than a part of the flexible portion situated inside the circumference defined by the terminal leg ends.

US Pat. No. 10,390,951

CLOCKING VALVE RETAINER

MEDTRONIC VASCULAR GALWAY...

1. A method of loading a prosthetic valve onto a delivery system comprising:rotating a second portion of a valve retainer to align a second orientation marking disposed on a radial outer surface of the second portion of the valve retainer with one of a plurality of first orientation markings disposed on a radial outer surface of a first portion of the valve retainer, wherein a proximal end of the second orientation marking on the outer surface of the second portion is distal to a distal end of the one of the plurality of first orientation markings on the outer surface of the first portion, and wherein the first portion and the second portion are axially fixed; and
attaching the prosthetic valve to the second portion of the valve retainer,
wherein attaching the prosthetic valve comprises attaching an attachment member on the prosthetic valve to an attachment structure on the second portion of the valve retainer, and
wherein the attachment structure is distal of and longitudinally aligned with the second orientation marking on the second portion of the valve retainer.

US Pat. No. 10,390,950

FLEXIBLE CATHETERS AND METHODS OF FORMING SAME

St. Jude Medical, Cardiol...

1. A delivery device for a collapsible prosthetic heart valve comprising:an inner shaft having a proximal end and a distal end;
an outer shaft disposed around the inner shaft and longitudinally moveable relative to the inner shaft; and
a distal sheath disposed about a portion of the inner shaft and forming a compartment with the inner shaft, the compartment being adapted to receive the prosthetic heart valve;
the outer shaft having a pattern of cutouts formed therein, the pattern including at least one ring around a circumference of the outer shaft, the at least one ring having at least one of the cutouts.

US Pat. No. 10,390,949

STAGED DEPLOYMENT DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS

St. Jude Medical, Cardiol...

1. A delivery device for a collapsible prosthetic heart valve, the delivery device comprising:an operating handle, including:
a frame defining a first longitudinal end and a second longitudinal end spaced apart in a longitudinal direction of the operating handle, and a movement space located between the first and second longitudinal ends;
a carriage assembly having a first longitudinal end and a second longitudinal end spaced apart in the longitudinal direction, the carriage assembly moveable in the longitudinal direction within the movement space, the first and second longitudinal ends of the carriage assembly located within the movement space; and
a first resheathing lock having a locked position and an unlocked position, the first resheathing lock in the locked position limiting movement of the carriage assembly in the longitudinal direction to a first intermediate position in the movement space, and the first resheathing lock in the unlocked position permitting movement of the carriage assembly in the longitudinal direction beyond the first intermediate position in the movement space; and
a catheter assembly, including:
a first shaft around which a compartment is defined, the first shaft being fixedly connected to the frame, the compartment being adapted to receive the valve in an assembled condition;
a distal sheath operatively connected to the carriage assembly, the distal sheath being moveable between a closed condition adapted to maintain the valve in the assembled condition and an open condition adapted to fully deploy the valve; and
an outer shaft connecting the carriage assembly to the distal sheath and at least partially surrounding the first shaft,
wherein movement of the carriage assembly to the first intermediate position moves the distal sheath to a condition between the closed condition and the open condition so that the valve is not fully deployed.

US Pat. No. 10,390,947

MEDICAL VALVE IMPLANT FOR IMPLANTATION IN AN ANIMAL BODY AND/OR HUMAN BODY

Biotronik AG, Buelach (C...

1. A medical valve implant for implantation in an animal body and/or human body, comprising:an implant structure configured as a medical heart valve; and
a base body that includes a collar extending in a circumferential direction around the implant structure and configured to radially expand, wherein the collar includes a first cell structure composed of a plurality of cells forming an inner cross section of the base body that is matched to an outer cross section of the implant structure and wherein the cells of the first cell structure are shaped to facilitate alignment of the valve prosthesis with a direction of blood flow, characterized in that the collar includes one or more second cell structures, wherein one of the one or more second cell structures is fastened to an inner contour of a cell of the first cell structure at two fastening points and is preloaded to move from a position that follows the inner contour of the cell to a position that extends radially outward relative to the cell of the first cell structure during expansion.

US Pat. No. 10,390,946

METHOD FOR THE PREPARATION OF BIOLOGICAL TISSUE FOR DRY USE IN AN IMPLANT

Biotronik AG, Buelach (C...

1. A method of preparing biological tissue for use as a component of a heart valve prosthesis comprising pretreating the tissue, and stabilizing the pretreated tissue, characterized in that, the step of pretreating the tissue comprises crosslinking the tissue with an aldehyde-containing solvent, wherein the aldehyde is glutaraldehyde or formaldehyde; and the step of stabilizing the pretreated tissue comprises exposing the tissue to three solutions for dimensional and structural stabilization, wherein a first solution contains polyethylene glycol having a mean molecular weight between 200 g/mol and 400 g/mol, a second solution contains glycerol, and a third solution contains polyethylene glycol having a mean molecular weight between 1,000 g/mol and 6,000 g/mol, wherein the tissue is exposed to the first and second solutions before the third solution.

US Pat. No. 10,390,945

PERCUTANEOUSLY IMPLANTABLE REPLACEMENT HEART VALVE DEVICE AND METHOD OF MAKING SAME

COLIBRI HEART VALVE LLC, ...

1. A replacement heart valve device, comprising:a stent member, the stent member configured to be compressible and expandable; and
a dry valve directly sutured to the stent member, wherein the dry valve includes two to four leaflets made of a treated mammalian pericardium tissue, wherein the treated mammalian pericardium tissue has been treated with glutaraldehyde, glycerol and gas sterilized, and wherein the treated mammalian pericardium tissue forming the dry valve has been subjected to light and mechanical compression to decrease the molecular distance of collagen fibers.

US Pat. No. 10,390,944

BRAIDED SUPPORT STRUCTURE

HLT, Inc., Maple Grove, ...

1. A braided tubular medical implant comprising:a braided tubular structure having a first configuration and a second configuration wherein the first configuration is an elongated, unfolded configuration and the second configuration is a deployed, folded configuration;
wherein said braided tubular structure includes:
at least one circumferential preformed fold area having wires intersecting at a first braid angle;
a preformed circumferential fold located within said circumferential preformed fold area;
at least one body area adjacent said circumferential preformed fold area in which said wires intersect at a second braid angle;
wherein said first braid angle is not equal to said second braid angle; and,
wherein the first braid angle being not equal to the second braid angle at least partially effects folding the braided tubular structure to form said second configuration.

US Pat. No. 10,390,943

DOUBLE ORIFICE DEVICE FOR TRANSCATHETER MITRAL VALVE REPLACEMENT

EVALVE, INC., Santa Clar...

1. An orifice valve device for attachment to a mitral valve defining at least two orifices, the device comprising:an anchoring and manifold assembly coupleable to a delivery catheter;
a peripheral ring anchoring system fluidly communicating with and secured to the anchoring and manifold assembly, the peripheral ring anchoring system including:
two expandable anchoring rings, wherein each expandable anchoring ring can be expanded within a respective orifice of the mitral valve so as to surround a perimeter of the respective orifice and form a corresponding opening, the two expandable anchoring rings being in fluid communication and disposed on opposite sides of the anchoring and manifold assembly whereby the anchoring and manifold assembly forms a portion of a perimeter of each of the corresponding openings;
two helical sutures, each of the two helical sutures being helically disposeable about a respective one of the two expandable anchoring rings to secure the respective one of the two expandable anchoring rings to leaflet tissue around the perimeter of the respective orifice of the mitral valve; and
two trap door valves, each trap door valve hingedly secured within a respective opening formed by the peripheral ring anchoring system, each trap door valve comprising:
a trap door body that selectively seals against a respective one of the two expandable anchoring rings extending around the perimeter of a respective orifice of the mitral valve during a systole portion of a cardiac cycle, the trap door body selectively unsealing relative to the one of the two expandable anchoring rings so as to open the corresponding opening and thus the respective orifice of the mitral valve, during a diastole portion of the cardiac cycle.

US Pat. No. 10,390,942

SPEECH VALVE FOR PERSONS HAVING UNDERGONE A LARYNGECTOMY OR TRACHEOTOMY

1. A speech valve for persons having undergone a laryngectomy or tracheotomy, comprising a housing with a proximal opening and a at least one filter at least partially received in the housing, the housing having a piston-like valve element, wherein the filter at least partially encompasses the valve element, wherein the housing includes a cover part having an opening for receiving the valve element, the proximal opening being located at an end of the housing opposite the cover part, wherein the valve element bears on the opening in a sealing manner, wherein the valve element is moved onto a valve seat disposed on the proximal opening in order to generate a closure position, and is returned to an open position of the speech valve in a spring-loaded manner, and wherein the valve element has a lower end facing toward the proximal opening, and when in the open position, forms a gap with the valve seat, through which an air flow is conducted.

US Pat. No. 10,390,941

AUTOMATED INTRAOCULAR LENS INJECTOR DEVICE

Novartis AG, Basel (CH)

1. A device for implanting an intraocular lens in the lens capsule of an eye, the device comprising:a tubular housing having a primary axis extending between front and rear ends of the housing;
a plunger longitudinally disposed within the housing and having first and second ends, the first end being disposed towards the front end of the housing;
an electric drive system disposed within the housing, the electric drive system including an electric motor and configured to cause longitudinal translation of the plunger along the primary axis of the housing;
a cartridge mount at or near the front end of the housing and configured to accommodate a removable insertion cartridge in alignment with the plunger so that an intraocular lens disposed in the insertion cartridge is displaced from the insertion cartridge as the plunger is translated towards the front end of the housing; and
a control circuit, electrically connected to the electric motor and configured to: monitor a back EMF signal from the electric motor caused by the force on the plunger; advance the plunger;
detect, based on the back EMF signal exceeding a predetermined threshold level, a critical point at which an axial compressive force on the lens suddenly increases;
in response to the detection of the back EMF exceeding the predetermined threshold level, retract the plunger from the critical point to a sufficient distance for material of the intraocular lens to relax;
pause after the plunger is retracted to allow the material of the intraocular lens to relax;
advance the plunger to the critical point a second time; and
continue to advance the plunger beyond the critical point at an accelerated rate to implant the intraocular lens.

US Pat. No. 10,390,940

INTRAOCULAR LENS INSERTION DEVICE

Hoya Corporation, Tokyo ...

1. An intraocular lens insertion apparatus, comprising:a main body including an intraocular lens storage region, a tapered transition part and a nozzle; and
a plunger, movable relative to the main body to push an intraocular lens along a lens travelling axis from the storage region and through the nozzle, including a rod having a proximal portion and a distal axial portion with an upper protrusion defining a distal end, a lower protrusion defining a distal end that is offset from the distal end of the upper protrusion in a first direction defined by the lens travelling axis, and an indentation defining a slot between the upper and lower protrusions;
wherein the upper protrusion and the lower protrusion are spaced from one another across the slot in a first second direction that is perpendicular to the lens travelling axis; and
wherein the lower protrusion defines a width in a third direction perpendicular to the lens travelling axis and perpendicular to the second direction, the slot defines a width that is at least as wide as the lower protrusion with a midpoint in the third direction, the upper protrusion defines a width in the third direction that is less that the width of the slot, and the upper protrusion is offset from the slot midpoint in the third direction.

US Pat. No. 10,390,939

MICRO-INCISION IOL AND POSITIONING OF THE IOL IN THE EYE

AMO GRONINGEN B.V., Gron...

1. An intraocular lens comprising: an optic disposed about an optical axis, the optic having an anterior surface and a posterior surface; at least two anterior projections coupled to and extending radially from the optic; and at least two posterior projections adjacent to the at least two anterior projections, wherein the at least two posterior projections are coupled to and extends radially from the optic, wherein the anterior and posterior projections are resiliently biased such that distal ends of the anterior projections and the posterior projections can be moved away from and toward each other, and wherein, when implanted, the distal ends of the at least two anterior projections and the at least two posterior projections are configured to grip an outside surface and an inside surface adjacent to a capsulorhexis on an anterior portion of an evacuated capsular bag.

US Pat. No. 10,390,938

OPHTHALMIC LENSES WITH ENHANCED SURFACE AND METHODS OF FABRICATION THEREOF

1. A method of making an intraocular lens, comprising:forming a support structure;
forming, using a first mold, a base optic having an anterior surface and an opposing posterior surface;
processing the base optic to change a physical characteristic of the base optic, wherein the base optic is spherical;
subsequent to processing the base optic, placing the base optic in a second mold and forming, using the second mold, a membrane, the membrane being affixed to at least one of the surfaces of the base optic, thereby fabricating a finished optic, wherein the membrane includes an outer surface that defines a plurality of echelettes of a diffractive grating, and further wherein the membrane and the spherical base optic together, provision an aspheric optic.

US Pat. No. 10,390,937

ACCOMMODATING INTRAOCULAR LENSES

PowerVision, Inc., Belmo...

1. An accommodating intraocular lens, comprising:an optic that includes
a deformable anterior element that includes an anterior most location of the optic, the deformable anterior element adapted to deform to change the power of the accommodating intraocular lens,
a posterior element that includes a posterior most location of the optic, and
an optic fluid chamber;
a first haptic that is secured to the optic and that extends radially outward from the optic, the first haptic having an anterior portion that extends further in the anterior direction than the anterior most location of the optic; and
a second haptic that is secured to the optic and that extends radially outward from the optic, the second haptic having a posterior portion that extends further in the posterior direction than the posterior most location of the optic,
the first and second haptic each comprising a material and a configuration such that they are adapted to deform in response to capsular bag reshaping.

US Pat. No. 10,390,936

OVERDRIVE PREVENTION FOR EXPANDABLE ANCHOR

MEDOS INTERNATIONAL SARL,...

1. A tendon anchoring system, comprising:an anchor assembly having
a sheath with a threaded lumen formed therein, and
a threaded expander screw configured to threadably engage the threaded lumen in the sheath such that the expander screw causes the sheath to expand outward to engage a bone hole; and
an inserter tool having
an elongate outer shaft having proximal and distal ends with an inner lumen extending therethrough, the distal end being configured to couple to a proximal end of the sheath, and
an elongate inner shaft having a distal drive tip configured to engage a corresponding drive recess formed in a proximal end of the expander screw, the inner shaft being rotatable relative to the outer shaft to thread the expander screw into the sheath, and the inner shaft being prevented from rotating relative to the outer shaft when the expander screw is fully threaded into the sheath to prevent over-insertion of the expander screw into the sheath.

US Pat. No. 10,390,935

SOFT TISSUE TO BONE REPAIR DEVICES, SYSTEMS, AND METHODS

CoNextions, Inc., Salt L...

1. A repair device system for fixating soft tissue to bone, the soft tissue extending longitudinally to define an axis thereof, comprising:a carrier member extending with a seamless, monolithic structure, the carrier member including multiple pad portions and a bone coupling portion, the carrier member defining a longitudinal axis such that the longitudinal axis of the carrier member is configured to extend along the axis of the soft tissue, each of the pad portions being aligned with an adjacent pad portion and each of the pad portions having at least two openings defined therein, the pad portions configured to be positioned over a side of the soft tissue, each of the multiple pad portions coupled to the adjacent pad portion with first struts and second struts, the first struts extending transversely relative to the longitudinal axis and the second struts extending longitudinally along and substantially parallel with the longitudinal axis, the first struts each extending with a first elongated structure and the second struts each extending with a second elongated structure, each first elongated structure extending longitudinally at an acute angle from, and continues in a direction alongside, one of the second elongated structures to one of the pad portions such that each of the first elongated structures longitudinally extends in a common plane as the one of the second elongated structures, the first strut moveable to facilitate movement of at least one of the pad portions relative to the longitudinal axis of the carrier member, the bone coupling portion including an elongated portion extending co-axially from one of the second struts; and
multiple anchors, each anchor being a separate and discrete structure relative to the carrier member, and each of the anchors sized and configured to be coupled to the carrier member so as to extend through the at least two openings of one of the multiple pad portions and so as to extend directly from one of the multiple pad portions and through the soft tissue to fixate the carrier member to the soft tissue.

US Pat. No. 10,390,934

MEDICAL DEVICE

Merlin MD Pte. Ltd., Sin...

1. A medical device for treating a bifurcation or trifurcation aneurysm, in a patient, occurring at a first artery, the first artery and a second artery joining to a third artery, the device comprising:an expandable latticework frame having first and second struts that each define a radially outermost edge, a radially innermost edge, a circumferential strut width, and a wall thickness between the radially outermost and innermost edges; and
a porous membrane that extends around and between the first and second struts, the membrane having a web portion that, between the first and second struts, extends only within a central region being (i) bounded radially between the radially outermost edges and the radially innermost edges of the first and second struts and (ii) bounded circumferentially between the first and second struts, the web portion defining a web thickness that is less than the wall thickness of the first or second struts,
wherein the porous membrane includes a first layer attached to the outer surface of the expandable latticework frame, an intermediate layer attached to the first layer, and a second layer covering the first layer and the intermediate layer, and
wherein the membrane is configured to (i) reduce blood supply into the aneurysm, and (ii) permit blood supply through pores of the membrane and into perforators and/or microscopic branches of the first artery so as not to inhibit blood supply functions of the perforators and/or microscopic branches.

US Pat. No. 10,390,933

DEVICES FOR FLUID FLOW THROUGH BODY VESSELS

LimFlow GmbH, Dresden (D...

1. A device for supplying fluid flow in a human or animal body, the device comprising:a first end portion configured to anchor the device in a first vessel;
a second end portion configured to anchor the device in a second vessel different than the first vessel, wherein the first end portion and the second end portion are diametrically expandable to anchor the device in the first vessel and the second vessel;
an intermediate portion located between the first end portion and the second end portion, the intermediate portion configured to permit movement of the first end portion and the second end portion relative to each another, the intermediate portion being diametrically expandable to dilate at least the intermediate portion;
a fluid pathway at least partially defined by the first end portion, the second end portion, and the intermediate portion;
a support structure comprising a mesh extending between the first end portion and the second end portion; and
a polymer tube at least partially defining a lumen, the lumen comprising at least a portion of the fluid flow pathway,
wherein the first end portion, the second end portion, and the intermediate portion are self-expanding, and
wherein the intermediate portion is configured to be expanded by a balloon after self-expanding.

US Pat. No. 10,390,932

STENT GRAFT WITH INTERNAL TUNNELS AND FENESTRATIONS AND METHODS OF USE

Bolton Medical, Inc., Su...

1. A thoraco-abdominal branch graft prosthesis, comprising:a) a main graft component having a luminal wall defining an open proximal end, an open distal end opposite the open proximal end, a main lumen extending from the open proximal end to the open distal end, and at least one main graft wall fenestration; and
b) at least one tunnel graft component having a tunnel graft luminal wall defining, at least in part, an open tunnel graft proximal end, an open tunnel graft distal end opposite the open tunnel graft proximal end, a tunnel graft lumen extending from the open tunnel graft proximal end to the open tunnel graft distal end, and at least one tunnel graft fenestration in the tunnel graft wall, wherein the tunnel graft component is within the main graft lumen and a major longitudinal axis of the tunnel graft lumen that is parallel to and spaced apart from a major longitudinal axis of the main lumen, and wherein the wall of the tunnel graft component is fixed to the wall of the main graft component, whereby the fenestration of the tunnel graft wall is aligned with the fenestration of the luminal wall.

US Pat. No. 10,390,931

DEVICES AND METHODS FOR ANATOMIC MAPPING FOR PROSTHETIC IMPLANTS

Aortica Corporation, Bel...

1. A method, comprising:receiving a digital representation of a portion of a patient's blood vessel, the digital representation including data representative of a first location of an anatomic feature of the patient's blood vessel;
modifying the data representative of the first location based on predicted deformation of the portion of the patient's blood vessel to determine a second location of the anatomic feature of the patient's blood vessel, the second location different than the first location; and
generating a patient-specific prosthesis having a fenestration at the second location.

US Pat. No. 10,390,930

METHOD FOR AORTIC BRANCHED VESSEL REPAIR

Bolton Medical, Inc., Su...

1. A method for implanting a prosthesis, comprising the steps of:a) delivering an aortic graft assembly that includes a tubular aortic component through an aorta to an aneurysm site of a patient, the tubular aortic component defining a tunnel lumen and having a proximal end and a distal end connected by a wall, the wall defining a wall aperture that is between the proximal end and the distal end, the wall aperture having a proximal end and a distal end, the proximal end of the wall aperture including an first plane extending perpendicular to a major longitudinal axis of the tubular aortic component when viewed orthogonally to the major longitudinal axis, the tubular aortic component being radially and releasably constrained by a distal clasp at a distal end of an outer control tube of a delivery device, and releasably attached by a retention component to a proximal clasp at the outer control tube proximal to the proximal clasp, the tubular aortic component further supported by a control catheter of the delivery device extending within the outer control tube, the aortic graft assembly further including a tunnel graft extending from the wall aperture and within the tunnel lumen of the tubular aortic component toward the proximal end of the tubular aortic component, wherein the length of the proximal end of the wall aperture in the first plane is greater than the diameter of the tunnel graft lumen in a second plane extending orthogonally to the major longitudinal axis at a point proximal to the proximal end of the wall aperture;
b) aligning the wall aperture over at least one vessel ostium at the aneurysm site of the patient; and
c) retracting the outer control tube, thereby releasing the tubular aortic component from the distal and proximal clasps, thereby deploying the tubular aortic component at the aneurysm site in the patient.

US Pat. No. 10,390,929

METHODS OF SELF-ALIGNING STENT GRAFTS

Bolton Medical, Inc., Su...

1. A method for automatic endovascular alignment of a prosthesis in a curved implantation site of a vessel, which comprises:providing a prosthesis delivery system with a distal handle, a longitudinally movable distal delivery assembly that includes an apex release lumen and a longitudinally movable guidewire lumen having a pre-curved distal portion within the apex release lumen and rotationally connected to the distal delivery assembly, the distal delivery assembly and the guidewire lumen being together rotatably mounted to the distal handle;
loading the prosthesis in the distal delivery assembly, the prosthesis including a longitudinal support that is fixed to the prosthesis at a superior longitudinal line of the guidewire lumen, to thereby form a loaded distal delivery assembly, whereby advancement of the loaded distal delivery assembly into the curved implantation site will cause axial rotation of the guidewire lumen and the prosthesis together about a longitudinal axis of the distal delivery assembly, and alignment of the longitudinal support with a superior longitudinal line of the curved implantation site;
positioning a guidewire at least into the curved implantation site of the vessel;
threading the guidewire lumen over the guidewire along with the loaded distal delivery assembly;
advancing the guidewire lumen and the loaded distal delivery assembly along the guidewire toward the curved implantation site; and
further advancing the guidewire lumen, the loaded distal delivery assembly, and the prosthesis that is loaded into the distal delivery assembly, along the guidewire and into the curved implantation site whereby advancement of the curved distal portion of the guidewire lumen into the curved implantation site causes rotation of the guidewire lumen, the loaded distal delivery assembly- and the prosthesis to rotationally align together about the longitudinal axis of the distal delivery assembly, to thereby align of the longitudinal support with the superior longitudinal line of the curved implantation site.

US Pat. No. 10,390,928

OPEN LUMEN STENT

BOSTON SCIENTIFIC SCIMED,...

1. A ureteral stent, comprising:an elongate body having a proximal end and a distal end and defining a single lumen with a substantially circular cross-sectional profile, and an opening in communication with the single lumen, the opening extending an entire length of the elongate body from the proximal end of the elongate body to the distal end of the elongate body, the elongate body having an inner surface and an outer surface disposed opposite the inner surface, the inner surface defining the single lumen, the elongate body defining at least one groove on the outer surface of the elongate body,
wherein the elongate body has a cross-sectional profile including a first end portion, a second end portion, and a middle portion between the first end portion and the second end portion, inner surfaces of the first end portion and the second end portion defining the opening, the first and second end portions being enlarged portions each having a thickness greater than the middle portion and configured to releasably couple to a guidewire.

US Pat. No. 10,390,926

ASPIRATION DEVICES AND METHODS

Insera Therapeutics, Inc....

1. A system for aspirating thrombi using an operator-selectable suction pattern, the system comprising:an external control panel that allows an operator to choose from any of a plurality of stored crescendo suction patterns during a thrombus aspiration procedure,
wherein each of the plurality of stored crescendo suction patterns comprises a repetitive cycle pattern having at least two different suction intensity levels,
wherein the at least two different suction intensity levels are selected from one of three suction intensity levels,
wherein a first suction intensity level is within a range between ?100 and ?350 mm Hg, wherein a second suction intensity level is within a range between ?351 and ?550 mm Hg, and wherein a third suction intensity level is within a range between ?551 and ?769 mm Hg,
wherein a first suction pattern of the plurality of stored crescendo suction patterns is configured for aspiration of soft clots,
wherein a second suction pattern of the plurality of stored crescendo suction patterns is configured for aspiration of hard clots; and
a vacuum pump comprising power electronics that generate the plurality of stored crescendo suction patterns.

US Pat. No. 10,390,925

MIGRATION RESISTANT EMBOLIC FILTER

C.R. Bard, Inc., Murray ...

1. An embolic filter, comprising:a) a head having a proximal end, a distal end having a first position, and a filter central longitudinal axis;
b) a plurality of appendages that include straight leg appendages and bent leg appendages, each of said plurality of appendages extending distally from the first position on the distal end of the head, said plurality of appendages including a first plurality of appendages providing a distal appendage end with a curved anchor, said curved anchor configured to engage an inner wall of a vein at a location spaced distally of the head and prevent the embolic filter from migrating in a cranial direction;
c) the said plurality of appendages including a second plurality of appendages that are said straight leg appendages, each having a straight leg central longitudinal axis, each straight leg appendage extending distally from the head at said first position, wherein each appendage of the second plurality has a distal most end, said distal most end having a caudal anchor located distally of the head and joined to the straight leg appendage, each said caudal anchor having a vein engagement surface configured to engage an inner wall of a vein at a location spaced distally of the head to prevent the embolic filter from migrating in a caudal direction;
d) wherein said straight leg central longitudinal axis intersects said vein engagement surface;
e) wherein the curved anchor is of a different configuration as compared to the caudal anchor of the straight legs;
f) wherein each said caudal anchor has a distal most tip, said vein engagement surface located proximally of said distal most tip and wherein there is a taper between the distal most tip and the said straight leg appendage proximally of said distal most tip, wherein said vein engagement surface is located at said taper and forms an obtuse angle with said straight leg appendage central axis;
g) wherein one or more of the appendages of the first plurality are longer than one or more of the appendages of the second plurality;
h) the filter having a pre-deployment position that aligns all of the appendages together distally of the head and next to said filter central longitudinal axis;
i) the filter having a deployed position wherein all of the appendages are spaced radially away from said filter central longitudinal axis, and wherein said vein engagement surface is configured to abut the vein inner wall; and
j) wherein in both the pre-deployment and deployed positions the said curved anchors and caudal anchors are closer to each other and closer to said filter central longitudinal axis than to the head.

US Pat. No. 10,390,924

SYSTEM AND METHOD FOR PELVIC FLOOR REPAIR

POP MEDICAL SOLUTIONS LTD...

1. A system for attaching an anchor to a ligament located outside of a tissue wall, the system comprising:a body-insertable mounting having a longitudinal axis;
a working channel extending at an angle with respect to said longitudinal axis, mounted onto said body-insertable mounting; and
a suture and penetrating anchor assembly which is configured to be axially displaceable along said working channel through said tissue wall and into anchoring relationship with said ligament,
said suture and penetrating anchor assembly including a proximity sensor at a distal end thereof.

US Pat. No. 10,390,923

IMPLANTABLE DEVICE FOR INTERNAL URINARY CONTROL

1. An apparatus for assisting the discharging of urine from a natural urinary bladder of a patient, the apparatus comprising:an implantable expandable member configured to be implanted inside of the urinary bladder,
an implantable control device for controlling the volume of the expandable member,
wherein the implantable control device is configured generate a pressure in the implantable expandable member exceeding 50 cm water pressure thereby assisting the discharging of urine.

US Pat. No. 10,390,922

DEVICES AND METHODS FOR DELIVERY OF ATTACHMENT DEVICES

Boston Scientific Scimed,...

1. An apparatus for delivering attachment devices, the apparatus comprising:a needle including a lumen and a distal opening;
a plurality of attachment devices disposed within the lumen of the needle, each attachment device including a first attachment part and a second attachment part, the first attachment part includes a first end portion and a second end portion, and an extending portion, the extending portion extending from at least one of the first end portion and the second end portion;
a connecting member coupled to the first attachment part and the second attachment part and configured to attach the first attachment part and second attachment part together, the connecting member being configured to be at least partially housed within at least one of the first attachment part or the second attachment part; and
an actuator configured to drive each attachment device out of the distal opening of the needle during a surgical procedure.

US Pat. No. 10,390,921

URINE FLOW CONTROL SYSTEM AND A MAGNETIC ACTUATOR DEVICE

MAGCATH APS, Copenhagen ...

1. A urine flow control system, comprising:a catheter device configured for insertion into a urethra, the catheter device including (1) a proximal end portion and an opposite distal end portion, (2) a conduit between the proximal end portion and the distal end portion, the conduit having a urine inlet opening at the proximal end portion and a urine outlet opening at the distal end portion, (3) a valve seat at the distal end portion, and (4) a magnet configured as a valve body that is magnetically biased toward a closed position against the valve seat to block an outflow of urine from the catheter device through the urine outlet opening; and
a magnetic actuator device configured for magnetically displacing the valve body from the valve seat to permit the outflow of urine from the catheter device through the urine outlet opening, wherein the magnetic actuator device comprises:
a housing with (1) a first open end removably coupled to the distal end portion of the catheter device so as to receive the outflow of urine from the catheter device, and (2) a second open end configured for discharging the urine from the housing; and
an actuator element at the first open end of the housing and comprising a body of a magnetically attractive material, wherein the actuator element is operable to move the valve body toward an open position when the distal end portion of the catheter device is coupled to the first open end of the housing.

US Pat. No. 10,390,920

DEVICE FOR INGUINAL LIGAMENT FIXATION AND SURGERY METHOD THEREOF

1. A surgery method for inguinal ligament fixation, comprising steps of: at a bladder lithotomy position of a patient, providing routine disinfection for abdominal and perineal skins, and applying a sterile towel; opening a bladder and back-folding a peritoneum; pushing down the bladder for exposing a vaginal wall; fixing a cervix and anterior vaginal wall sling of a suspension mesh on a cervical isthmus with several absorbable or non-absorbable sutures; respectively suturing two sacral ligament and posterior vaginal wall suspension arms of the suspension mesh on a posterior vaginal wall, and fixing the sacral ligament and posterior vaginal wall suspension arms on an inguinal ligament; pulling out two inguinal ligament suspension arms of the suspension mesh along outside portions of peritoneum at two sides of an uterus; opening the peritoneum at a position where a round ligament is attached on the uterus, and suturing the suspension mesh on a myometrium avascular zone under the round ligament; opening the peritoneum below the round ligament; outside the peritoneum and parallel to the round ligament, passing the suspension mesh through anterior superior iliac crest inguinal ligament, fascia and aponeurosis which directly reach an inlet of an inguinal canal, and dragging the suspension mesh until a pre-set length is reached; then opening surface peritoneum of the inguinal ligament and a fascia, and fixing the two inguinal ligament suspension arms on the inguinal ligament, the fascia and the aponeurosis; closing all peritoneal incisions so as to place the suspension mesh outside the peritoneum, and then closing an abdomen.

US Pat. No. 10,390,919

INSPECTION APPARATUS FOR OSSEOINTEGRATION OF IMPLANTS

National Central Universi...

1. An inspection apparatus for osseointegration of implants, comprising:an inspection base;
a holding end, disposed at one end of said inspection base, further including a signal processing module and a wireless transmission module disposed inside of said holding end, and said signal processing module connected electrically with said wireless transmission module; and
an inspection end, disposed at the other end of said inspection base and on one side of said holding end, further including an inspection probe disposed at one of said inspection end, one end of said inspection probe including one or more excitation device and a receiver, said one or more excitation device and said receiver located on the same side of said inspection probe, and said excitation device and said receiver connected electrically with said signal processing module;
where said inspection apparatus approaches an object under inspection; said signal processing module enables said excitation device to generate an excitation source to vibrate said object under inspection in a non-contact manner; meanwhile, said receiver receives the vibration response signal of said object under inspection; said signal processing module analyzes said vibration response signal and gives a displacement difference; and said wireless transmission module transmits said displacement difference to an electronic apparatus.

US Pat. No. 10,390,918

VIBRATING TOOTHBRUSH

Colgate-Palmolive Company...

1. An oral care implement comprising:a body formed of rigid material and extending from a proximal end to a distal end along an axis;
a mechanical vibratory device located in the body and circumferentially surrounded by the rigid material, the mechanical vibratory device including a motor and an eccentric weight and configured to generate vibrations;
the body having a first axial portion located between the motor and the proximal end, a second axial portion located between the motor and the distal end, and a third axial portion axially aligned with the motor, wherein the eccentric weight is located in the second axial portion of the body; and
the body comprising a vibration-reducing section, at least a portion of the vibration-reducing section being located on the third axial portion of the body and comprising an elastomeric material exposed on an outer surface of the body;
wherein the rigid material of the body extends continuously from the proximal end to the distal end.

US Pat. No. 10,390,917

POWERED ORAL CARE IMPLEMENT

Colgate-Palmolive Company...

1. A powered toothbrush comprising:a handle;
a power source;
a head including a cavity and disposed at a distal end of the handle, the cavity bounded by a floor and a peripheral side-wall completely surrounding the cavity, the cavity having an open top end defined by the peripheral side-wall;
an electrically conducting element disposed in the cavity and electrically connected to the power source, wherein application of an electrical current from the power source to one or more of the electrically conducting elements generates a magnetic field; and
a movable cleaning element connected to the head and covering the open top end of the cavity, the movable cleaning element movable relative to the cavity and comprising a bristle support member disposed at least partially over the cavity, a plurality of bristles extending from the bristle support member in a direction away from the cavity, and a ferromagnetic member;
wherein the magnetic field selectively at least one of attracts and repels the ferromagnetic member to move the movable cleaning element relative to the electrically conducting element.

US Pat. No. 10,390,916

SALIVA EJECTOR APPLIANCE

1. A saliva ejector system comprising:a saliva ejector configured to:
suction materials from a patient's oral cavity, and
a saliva ejector appliance comprising:
an elongate member having a front face, a rearward portion, and a forward head portion;
the front face having a longitudinal groove configured to hold therein in a snap-fit held position and affixed in place, the saliva ejector along generally an entire length of the front face with a distal end of the saliva ejector being spaced a small distance rearwardly from an end of the forward head portion, wherein the forward head portion is continuous with the rearward portion in a longitudinal direction;
the rearward portion forming an operator handle portion of the appliance when the saliva ejector is in the held position allowing an operator grasping the handle portion to controllably move the forward head portion in the patient's oral cavity in a saliva ejection procedure; and
the handle portion being longer than the head portion, and
wherein the saliva ejector appliance is configured to:
stop the saliva ejector at the oral cavity by holding in place the saliva ejector to the front face; and
protect soft tissue in the patient's oral cavity by extending past a tip of the saliva ejector and thereby preventing the aspiration of soft tissue.

US Pat. No. 10,390,915

ORAL CARE IMPLEMENT WITH APPLICATOR

Colgate-Palmolive Company...

1. An oral care implement comprising:a body comprising a handle and a head coupled to a distal end of the handle, the body extending along a longitudinal axis;
at least one tooth cleaning element located on the head;
a store of oral care material located within the body;
an applicator on the handle, the applicator comprising a plurality of outlets in fluid communication with the store of oral care material, the plurality of outlets located on a concave dispensing surface of the applicator; and
an actuator operably coupled to the store of oral care material to dispense the oral care material through the plurality of outlets.

US Pat. No. 10,390,914

METHOD FOR PROCESSING PREFABRICATED PROSTHETIC TEETH

Kulzer GmbH, Hanau (DE)

1. A method for processing prosthetic teeth for the production of a full denture or at least a partial denture with at least two prosthetic teeth comprising the following method steps:(a) inserting at least two prefabricated prosthetic teeth having coronal sides and basal sides into an elastic mold, wherein the coronal sides of the prosthetic teeth are inserted into recesses in the elastic mold,
(b) attaching a clamping device to the elastic mold if a clamping device is not already attached to the elastic mold, and after inserting the prosthetic teeth into the elastic mold, applying a mechanical pressure to the elastic mold with the clamping device, wherein the pressure exerts a force onto the prosthetic teeth inserted into the elastic mold via the elastic mold and the prosthetic teeth are thereby affixed in the elastic mold,
(c) positioning and aligning the prosthetic teeth in the elastic mold in such a manner in relation to each other that the prosthetic teeth comprise a desired position and desired alignment in relation to each other which they should have in the partial denture to be produced or full denture to be produced,
(d) affixing the elastic mold with the clamping device and prosthetic teeth in a defined position in a holder of a CAM device for removing material of the prosthetic teeth with a CAM method,
(e) basally ablating at least one of the prosthetic teeth affixed in the elastic mold with the CAM method,
(f) connecting the prosthetic teeth affixed in the elastic mold to a denture base on their respective basal sides after at least one of the prosthetic teeth has been basally ablated, and
(g) following connecting the prosthetic teeth to the denture base, releasing the elastic mold from the prosthetic teeth.

US Pat. No. 10,390,913

DIAGNOSTIC INTRAORAL SCANNING

Align Technology, Inc., ...

1. A method comprising:displaying a three-dimensional (3D) model of a patient's dental arch;
displaying a viewing window over at least a portion of the 3D model of the patient's dental arch;
receiving, from a user, a change in a relative position between the viewing window and the 3D model of the patient's dental arch;
identifying, from both the 3D model of the patient's dental arch and a plurality of images of a patient's dental arch taken from different angles and positions relative to the patient's dental arch, a near-infrared (near-IR) image taken at an angle and position that approximates a relative angle and position between the viewing window relative to the 3D model of the patient's dental arch; and
displaying the identified near-IR image taken at the angle and position that approximates the angle and position between the viewing window relative to the 3D model of the patient's dental arch.

US Pat. No. 10,390,912

THERMOFORMING AIDS AND METHODS

Loren S. Adell, Sunnyval...

1. A method of using a thermoforming aid to form a thermoformable sheet onto an object to create an impression of the object in the thermoformable sheet, the method comprising:placing a thermoforming aid which comprises a thermoformable sheet having an inherent tendency to curl and a curl-resistant element which is in surface-to-surface contact with a surface of the thermoformable sheet to prevent the thermoformable sheet from curling, on an open-center platen of a thermoforming machine by adhering a perimeter margin of a lower surface of one of the thermoformable sheet and the curl-resistant element to the platen;
placing an object underneath the thermoformable sheet; and
operating, the thermoforming machine to heat the thermoformable sheet and cause the heated thermoformable sheet to form onto an object and create an impression of at least a portion of the object in the thermoformable sheet,
in which adhering a perimeter margin of a lower surface of one of the thermoformable sheet and the curl-resistant element to the platen comprises adhering a perimeter margin of a lower surface of the thermoformable sheet to the platen, and
in which the adhering the perimeter margin of a lower surface of the thermoformable sheet to the platen comprises adhesively adhering a perimeter margin of a lower surface of the thermoformable sheet to the platen using adhesive which is on the perimeter margin of the lower surface of the thermoformable sheet.

US Pat. No. 10,390,911

ABUTMENT POSITION LOCATOR

Nobel Biocare Services AG...

1. Fitting for insertion into a dental implant in an insertion orientation defining a central insertion axis, comprising:a body portion extending along a central axis;
at least one resilient spring member extending distally from a distal end of the body portion; and
an alignment feature extending distally from the distal end of the body portion, the alignment feature configured to align the fitting relative to the dental implant about the insertion axis,
wherein the alignment feature is positioned distally beyond a distal end of the at least one resilient spring member,
wherein the alignment feature comprises a closed structure and at least one opening formed in the closed structure,
wherein one of the at least one spring member is disposed in the at least one opening of the alignment feature,
wherein the opening is a through hole on a peripheral portion of the alignment feature such that an axis passing through the opening is substantially perpendicular to the central axis.

US Pat. No. 10,390,908

UNIVERSAL ALIGNING ADAPTOR SYSTEM AND METHODS

1. A method for manufacturing a dental component comprising:receiving electronic vertical and horizontal position data of an adaptor seated on an implant in a patient's jaw, said adaptor having an adaptor reference indicium that is co-operable with a prosthetic reference indicium of a prosthetic component to position the adaptor into a repeatable vertical and horizontal predetermined position in relation to the implant, the electronic vertical and horizontal position data including electronic adaptor reference indicium data representative of the adaptor reference indicium position and electronic prosthetic reference indicium data representative of the prosthetic reference indicium position;
translating the electronic position data into electronic manufacturing device codes for a milling or printing program;
transmitting the electronic manufacturing device codes to a device configured to manufacture the prosthetic component, such that the manufactured prosthetic component is configured to be inserted on the implant such that the prosthetic component is in the preferred position; and
manufacturing the prosthetic component.

US Pat. No. 10,390,907

METHOD FOR PRODUCING TRAYS FOR BRACKETS

1. A method of producing individual trays for positioning orthodontic brackets on a patient's teeth, the method comprising:a) producing a model, the model comprising a replica of at least portions of at least two tooth crowns of the patient's teeth;
b) arranging a bracket replica or bracket replica part on each of the at least portions of the at least two tooth crowns of the model, wherein the bracket replica or bracket replica part comprises a coronal wing; and wherein arranging of the bracket replica or bracket replica part includes positioning the bracket replica or bracket replica part in a desired position on an exterior surface of each of the at least portions of the at least two tooth crowns such that the bracket replica or bracket replica part is extending on said exterior surface in an occlusal-gingival direction; and
c) producing at least two trays, each of said at least two trays being produced by forming at least one impression of the model with the positioned bracket replica or bracket replica part on each of the at least two tooth crowns thereon; the at least two trays each comprising: an impression of at least an occlusal portion of each of the at least two tooth crowns and of at least a coronal portion including at least the coronal wing of the bracket replica or bracket replica part, wherein said impression extends gingivally at most to an end of a wire guide of the bracket replica or bracket replica part, the wire guide being arranged gingivally of the coronal wing of the bracket replica or bracket replica part when viewed vertically from the occlusal portion of each of the at least two tooth crowns.

US Pat. No. 10,390,906

MEDICAL LUMINAIRE

11. A medical luminaire for intraoral illumination of a surgical field, the medical luminaire comprising:a plurality of illuminating units, each illuminating unit including a LED light source, a collimator and at least one diverging lens, each illuminating unit generating a field of light in an object plane, wherein each illuminating unit of the plurality of illuminating units is coupled to a common carrier at different locations on the common carrier and oriented so that the fields of light generated by each illuminating unit of the plurality of illuminating units substantially coincide at the object plane; and
a common diffuser for the plurality of illuminating units positioned downstream of the plurality of illuminating units, wherein the common diffuser is configured to widen the field of light generated by each illuminating unit and to lower a contrast gradient in a marginal region of each field of light, wherein the marginal region is where the field of light of each illuminating unit do not perfectly coincide in the object plane.

US Pat. No. 10,390,905

SURGICAL GUIDING TOOL, METHOD AND KIT FOR PLACING DENTAL IMPLANTS

Drs. Bettens-De Pooter BV...

12. A method for guiding a drilling system, using a device suitable for the subsequent positioning of a pterygoid dental implant, comprising:a. a handle extending along a longitudinal axis and having a proximal and a distal end;
b. and a bifurcated abutment at the distal end and at the proximal end of the handle, each comprising two legs, whereby a first of the bifurcated abutment is adapted to encircle the left maxilla at the processus pyramidalis ossis palatini and/or the processus pterygoideus ossis sphenoidalis and/or the tuberosity of the left maxilla, and is adapted to fit over a relief in the bone structure at the sutura pterygomaxillaris of the left maxilla; and whereby a second of the bifurcated abutment is adapted to encircle the right maxilla at the processus pyramidalis ossis palatini and/or the processus pterygoideus ossis sphenoidalis and/or the tuberosity of the right maxilla, and is adapted to fit over a relief in the bone structure at the sutura pterygomaxillaris of the right maxilla; and
whereby the second leg of at least one abutment is generally straight or slightly bent;
said method comprising the following steps:
a. administering an anesthetic to a patient;
b. making an incision, between 4 to 20 mm long in the mucosa, muscles and periosteum down to the bone;
c. partially introducing the device in the mouth of a patient, so that the appropriate abutment is introduced in the mouth of the patient;
d. mounting the device onto the upper jaw of the patient;
e. positioning the device so that:
a. an angulation of the longitudinal axis of the handle relative to the Frankfort plane of the patient from a sagittal view is reached either comprised between 30° and 90°, either between 40° and 50° or 67.5° and 77.5°, or either about 45° or 72.5°;
b. and a buccopalatal angulation of the longitudinal axis of the handle relative to the Frankfort plane is reached comprised between 65° and 110° from a frontal view, or about 81.3°;
f. drilling into the upper jaw along the longitudinal axis of the handle;
wherein mounting the device onto the upper jaw of the patient is executed by encircling the processus pyramidalis ossis palatini and/or the tuberosity of the maxilla and/or the processus pterygoideus ossis sphenoidalis with the introduced abutment.

US Pat. No. 10,390,904

ORTHODONTIC SYSTEMS

1. An orthodontic system, comprising:at least one orthodontic bracket configured to be attached to a surface of a tooth, the at least one orthodontic bracket defining an archwire slot, the at least one orthodontic bracket comprising
a base configured to be attached to the surface of the tooth,
a gear system that comprises a first gear,
a motor to drive the gear system,
an integrated circuit to control the motor,
an archwire placed in the archwire slot, and
a first member and a second member both attached to the base, the first and second members being spaced apart to define the archwire slot, wherein the first member comprises the first gear and a first rod, the first rod has a first portion having notches that engage the first gear, the first rod has a second portion that extends into the archwire slot, when the first gear rotates in a specified direction, the first gear drives the first rod in which the first rod is configured to contact the archwire and apply a first force to the archwire; and
a computer server configured to send instructions to the integrated circuit in the at least one orthodontic bracket;
wherein the integrated circuit is configured to control the motor according to the instructions from the computer server to drive the gear system to apply a force to the archwire.

US Pat. No. 10,390,903

ILLUMINATED APPARATUS WITH TELESCOPING FOR ELECTROCAUTERY DEVICES AND METHOD OF USE

1. An illuminating device for use with an electrocautery device comprising:a mounting portion connected to a telescoping portion, the mounting portion having a distal end and a proximal end, and a length extending therebetween;
a mount disposed between the distal end and the proximal end of the mounting portion, the mount defining a space to receive a body of the electrocautery device, and the mount further comprising at least one projection for frictional contact with the body of the electrocautery device on a bottom side of the mount, the space to receive the body of the electrocautery device further comprising an opening to allow one or more controls on the body of the electrocautery device to be accessed when the body of the electrocautery device is located within the mount;
the mounting portion further comprising a connector disposed on the proximal end, the connector attached to a proximal end of a hollow portion, the hollow portion located within the mounting portion and extending from the proximal end to the distal end of the mounting portion, the hollow portion being above the mount;
the telescoping portion defining a void for an electrocautery blade of the electrocautery device to pass therethrough;
the telescoping portion having a distal end and a proximal end, and a light source disposed on the distal end of the telescoping portion, the telescoping portion configured to telescope relative to the mounting portion from a first, retracted position wherein the proximal end of the telescoping portion abuts the distal end of the mounting portion, to a second, extended position wherein there is a space between the proximal end of the telescoping portion and the distal end of the mounting portion;
the distal end of the telescoping portion further comprising a smoke evacuation void positioned above the void for the electrocautery blade of the electrocautery device, the smoke evacuation void connected to a tube for smoke evacuation, the tube for smoke evacuation passing through the hollow portion of the mounting portion, such that the telescoping portion comprising the void for the electrocautery blade of the electrocautery device telescopes relative to the electrocautery blade of the electrocautery device, and wherein the smoke evacuation void and the light source telescope together relative to the electrocautery blade.

US Pat. No. 10,390,902

SYSTEM AND METHOD FOR INSTRUMENT TRACKING

HCL TECHNOLOGIES LIMITED,...

1. A device for tracking one or more instrument in a surgical kit, the device comprising:a magnetic sensor, wherein the magnetic sensor is configured to transmit one or more signals upon detecting a change in a state of a surgical kit, wherein the state is one of an open state and a closed state;
one or more of a load cell and a Piezo sensor, wherein the one or more of the load cell and the Piezo sensor are activated based on the one or more signals; and
a machine control unit coupled to the magnetic sensor and the one or more of the load cell and the Piezo sensor, wherein the machine control unit is capable of executing instructions to perform steps of:
receiving the one or more signals from the magnetic sensor;
activating the one or more of the load cell and the Piezo sensor based on the one or more signals;
receiving data from the one or more of the load cell and the Piezo sensor, wherein the data is associated with one or more instruments within the surgical kit;
computing a current state associated with each of the one or more instruments based on the data, and historical data, wherein the current state is one of: instrument present, instrument absent, and instrument present in reduced quantity;
transmitting the current state of the surgical kit, the current state associated with each of the one or more instruments and a location co-ordinate of the surgical kit via a communication channel based on a signal strength of the communication channel; and
deactivating the one or more of the load cell and the Piezo sensor, thereby tracking one or more instruments in the surgical kit.

US Pat. No. 10,390,901

OCULAR INJECTION KIT, PACKAGING, AND METHODS OF USE

CLEARSIDE BIOMEDICAL, INC...

1. An apparatus, comprising:a first tray member having a plurality of walls that define a first volume and an opening that provides access to the first volume;
a second tray member having a plurality of walls that define a second volume and an opening that provides access to the second volume, a wall from the plurality of walls of the second tray member including a retainer extending from the wall from the plurality of walls of the second tray member and configured to retain at least a portion of a medicament delivery device within the second volume, the opening of the second tray member providing removal access of the medicament delivery device from within the second volume,
in a first configuration, the second tray member is disposed within the first volume of the first tray member such that access to the medicament delivery device within the second volume is inhibited by a wall from the plurality of walls of the first tray member,
in a second configuration, the second tray member is physically separate from the first tray member to allow access to the medicament delivery device within the second volume; and
a cover member coupled to the first tray member about the opening, the cover member configured to maintain sterility of the first volume.

US Pat. No. 10,390,900

SURGICAL INSTRUMENT ARRANGEMENT AND DRIVE TRAIN ARRANGEMENT FOR A SURGICAL INSTRUMENT, IN PARTICULAR A ROBOT-GUIDED SURGICAL INSTRUMENT, AND SURGICAL INSTRUMENT

KUKA Deutschland GmbH, A...

1. A surgical instrument assembly, comprising:a modular motor drive unit which has an output drive assembly with at least one output drive element,
an instrument shaft releasably connected to the modular drive unit, and having an input drive assembly with at least one input drive element,
wherein the output drive assembly and the input drive assembly can be coupled to one another by a mechanical interface,
the mechanical interface comprising at least one one-sided linkage, wherein the output drive assembly and the input drive assembly each has at least one pair of output drive elements or input drive elements, respectively, running in opposing directions, wherein compressive forces are transmittable and tensile forces are not transmittable between each output drive element and corresponding input drive element,
wherein each output drive element and corresponding input drive element are arranged on opposite sides of a sterile barrier and in contact with the sterile barrier, and
wherein at least one of the output drive elements or the input drive elements comprises a pin, and is coupled with a rocker in such a manner that rotational movement of the rocker is converted to movement of the pin in a direction only along a longitudinal axis of the pin.

US Pat. No. 10,390,899

ARTICULATING SURGICAL ACCESS SYSTEM FOR LAPAROSCOPIC SURGERY

Covidien LP, Mansfield, ...

1. A surgical system, comprising:a first arm having a first longitudinal passageway defined therethrough and configured to receive a surgical instrument therein, the first arm having a proximal portion and a distal portion, the distal portion including a first articulatable segment and a second articulatable segment that are longitudinally spaced from one another;
a first articulation assembly coupled to the proximal portion of the first arm and having a first state and a second state, the first articulation assembly configured to transition the first articulatable segment of the first arm between a first articulated configuration and a second articulated configuration in response to the first articulation assembly transitioning between the first state and the second state; and
a second articulation assembly coupled to the proximal portion of the first arm, the second articulation assembly having a third state and a fourth state and configured to transition the second articulatable segment of the first arm between a third articulated configuration and a fourth articulated configuration independent of articulation of the first articulatable segment of the first arm in response to the second articulation assembly transitioning between the third state and the fourth state, the first and second articulatable segments transitionable to another articulated configuration from one of the articulated configurations.

US Pat. No. 10,390,897

MEDICAL DEVICE ADAPTER WITH WRIST MECHANISM

Covidien LP, Mansfield, ...

1. A surgical device having a drive mechanism comprising:a proximal transmission shaft defining a first longitudinal axis, the proximal transmission shaft including a connector sleeve disposed at a proximal end thereof and a first gear disposed at a distal end thereof, wherein the connector sleeve is couplable to the surgical device;
a middle transmission shaft including a second gear disposed at a proximal end thereof and meshingly engaged with the first gear and a third gear disposed at a distal end thereof, the middle transmission shaft defining a second longitudinal axis, the middle transmission shaft movable relative to the proximal transmission shaft from a first position where the first and second longitudinal axes are in a parallel orientation to a second position where the first and second longitudinal axes are in a non-parallel orientation; and
a distal transmission shaft including a fourth gear disposed at a proximal end thereof and meshingly engaged with the third gear, the distal transmission shaft defining a third longitudinal axis, the distal transmission shaft movable relative to the proximal and middle transmission shafts,
wherein the first, second, third and fourth gears define an elliptical shape along each respective axis of the first, second, and third longitudinal axes, the first, second, third, and fourth gears maintaining rotatable engagement during a respective movement of the proximal, middle, and distal transmission shafts.

US Pat. No. 10,390,896

FORCE SENSOR TEMPERATURE COMPENSATION

Intuitive Surgical Operat...

1. A force sensor apparatus, for use with a surgical instrument including a shaft and a wrist joint coupled to an end effector, the surgical instrument being operably couplable to a manipulator arm of a robotic surgical system, comprising:a plurality of strain gauges;
a tube portion including a proximal end, a distal end, a plurality of radial ribs that run along and radiate from a centerline axis of the tube, wherein a different strain gauge, from among the plurality of strain gauges, is positioned over each rib of the plurality of radial ribs to reduce temperature differences between opposing strain gauges by providing a direct thermal pathway between opposing strain gauges;
the proximal end of the tube portion operably couplable to the shaft of the surgical instrument;
the distal end of the tube portion operably couplable to the wrist joint of the surgical instrument; and
a thermal shunt shell over an outer surface of the tube portion.

US Pat. No. 10,390,895

CONTROL OF ADVANCEMENT RATE AND APPLICATION FORCE BASED ON MEASURED FORCES

Ethicon LLC, Guaynabo, P...

1. A robotic surgical system comprising:a first robotic arm;
a first tool assembly coupled to the first robotic arm, the first tool assembly comprising
a first shaft extending distally from a first housing;
a first end effector coupled to a first distal end of the first shaft, the first end effector being configured to manipulate a tissue of a patient; and
a first sensor operatively coupled to the first end effector and configured to sense a first force applied to the first end effector by the tissue;
a second robotic arm;
a second tool assembly coupled to the second robotic arm, the second tool assembly comprising
a second shaft extending distally from a second housing;
a second end effector coupled to a second distal end of the second shaft, the second end effector being configured to treat the tissue; and
a control system configured to control, based on the sensed first force applied to the first end effector, a velocity of movement of the second end effector.

US Pat. No. 10,390,894

SURGICAL INSTRUMENT MANIPULATOR ASPECTS

Intuitive Surgical Operat...

1. A remote center manipulator comprising:a mounting base;
an instrument holder configured to couple with a surgical instrument; and
a linkage coupling the instrument holder to the mounting base, the linkage comprising a yaw joint, a parallelogram linkage portion, and a conical sweep joint;
the yaw joint being positioned to rotate the instrument holder about a yaw axis that intersects a remote center of manipulation;
the parallelogram linkage portion comprising a first joint, a second joint, and a third joint that are constrained to rotate the instrument holder about a pitch axis that intersects the remote center of manipulation; and
the conical sweep joint being configured to reorient the yaw joint and the parallelogram linkage portion about a conical sweep axis that intersects the remote center of manipulation, the conical sweep axis being non-parallel with the yaw axis.

US Pat. No. 10,390,893

SYSTEMS AND METHODS FOR ALIGNING AN ELONGATE MEMBER WITH AN ACCESS SITE

Auris Health, Inc., Redw...

19. A method of aligning an elongate member, controlled by an instrument driver, with an access site, the method comprising:coupling a stabilizer to the access site on a patient, wherein the stabilizer is engageable with the patient, wherein the stabilizer comprises a base with an opening formed therethrough for receiving the elongate member;
coupling the stabilizer to an alignment joint, the alignment joint comprising at least one position sensor;
determining a position of the alignment joint based on an output of the at least one position sensor;
determining a position of the stabilizer based on the output of the at least one position sensor; and
automatically aligning the instrument driver with the stabilizer on the patient based on the determined positions of the stabilizer and the alignment joint.

US Pat. No. 10,390,892

SYSTEM AND METHODS FOR UPDATING PATIENT REGISTRATION DURING SURFACE TRACE ACQUISITION

1. A method of performing a patient registration using a surgical navigation system, having a processor, in a medical procedure, comprising:initializing a surface trace acquisition;
recording one or more surface traces;
receiving a patient image of a patient anatomy;
extracting a surface from the patient image;
computing a registration transform for patient registration between the one or more surface traces and the patient image extracted surface, the patient registration dynamically updated during the surface trace acquisition;
segmenting the patient image into a plurality of regions, each region of the plurality of regions containing an anatomical landmark;
determining a spatial distribution of surface traces among the plurality of regions;
determining whether the spatial distribution in relation to each region of the plurality of regions minimizes deviance below a threshold; and
if the spatial distribution in relation to any region of the plurality of regions is determined as exceeding the threshold, providing information relating to such region.

US Pat. No. 10,390,891

HOLOGRAM LENS FOR POSITIONING AN ORTHOPEDIC IMPLANT

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus for positioning an orthopedic implant, the apparatus comprising:a magnetic receiver, which is configured to sense respective components of one or more magnetic fields generated by a field-generating device coupled to the orthopedic implant, and to produce corresponding electrical signals indicative of the sensed components of the one or more magnetic fields;
a processor, which is configured to calculate, based on the electrical signals, a position of the orthopedic implant within an organ of a patient; and
a personal display device, which is configured to display at least part of the orthopedic implant overlaid on a scene, based on the position calculated by the processor, wherein the displayed at least part of the orthopedic implant comprises a three-dimensional (3D) hologram of the at least part of the orthopedic implant.

US Pat. No. 10,390,890

NAVIGATIONAL FEEDBACK FOR INTRAOPERATIVE WAYPOINT

SYNAPTIVE MEDICAL (BARBAD...

1. A method of providing navigational feedback during a surgical procedure by way of a processor, the method comprising:providing an augmented reality display, displayed on an augmented reality display device coupled with the processor, for viewing a three-dimensional (3D) position and an orientation of a surgical tool in a surgical field during the surgical procedure, the position and the orientation of the surgical tool being tracked by a medical navigation system coupled with the processor, and the augmented reality display comprising a virtual representation of the surgical tool superimposed on a live, real-time image of the surgical field;
automatically intraoperatively creating a waypoint and storing, in a memory coupled to the processor, a selected intraoperative start time, a selected intraoperative end time, a selected intraoperative 3D position, and a selected intraoperative orientation of the surgical tool as a stored start time, a stored end time, a stored position, and a stored orientation of the waypoint, the stored position comprising x, y, and z coordinates, and the stored orientation comprising pitch, yaw, and roll;
providing feedback to indicate the stored start time, the stored end time, the stored position, and the stored orientation of the waypoint, the feedback comprising information to guide return of the surgical tool to the waypoint after the surgical tool has been moved from the selected intraoperative position and the selected intraoperative orientation; and
when the surgical tool has returned to the stored position and the stored orientation of the waypoint prior to the stored end time, providing further feedback indicating a successful return of the surgical tool to the waypoint.

US Pat. No. 10,390,889

REMOVABLE NAVIGATION SYSTEM AND METHOD FOR A MEDICAL DEVICE

1. A medical navigation device, comprising:a sheath comprising a material, the sheath configured to cover at least a portion of a medical device configured for navigation in a body lumen of a patient, wherein the sheath comprises a first opening, a second opening, and a lumen therebetween, wherein the first opening, the second opening, and the lumen are each sized and configured such that a portion of the medical device may removably pass therethrough; and
a positioning sensor comprising an electromagnetic coil affixed within the material of the sheath so that the sheath and the positioning sensor are removable from the medical device and from the body lumen while the medical device remains in the body lumen, wherein the electromagnetic coil is sized and configured such that a portion of the medical device may removably pass therethrough, and wherein the electromagnetic coil is electrically coupled to conductors extending longitudinally along the sheath from the electromagnetic coil to a sheath proximal end located outside of the body lumen and patient while the medical device remains in the body lumen so as to enable connection of the conductors to a navigation and tracking system, and
wherein the electromagnetic coil is sized and configured to produce a signal that can be interpreted by a signal processing unit and such that a portion of the medical device may pass therethrough.

US Pat. No. 10,390,888

INTRAVASCULAR CATHETER FOR MODELING BLOOD VESSELS

International Business Ma...

1. A method of generating a 4-Dimensional model comprising:capturing imagery of a catheter and a vessel as the catheter is directed through the vessel to a location of interest, wherein the catheter is disposed on a guidewire;
constructing a 3-Dimensional time varying reference curve describing a trajectory of the guidewire; and
constructing a time varying 3-Dimensional model of the artery comprising image frames mapped to points on the reference curve,
wherein constructing the 3-Dimensional time varying reference curve describing a trajectory of the guidewire further comprises:
acquiring at least two angiogram runs from different viewing angles with the guidewire, and a proximal marker, a distal tip marker, and a lens marker visible over a complete cardiac cycle;
mapping each image frame of the at least two angiogram runs to positions within the cardiac cycle;
selecting a subset of the image frames of the at least two angiogram runs that encompass at least the cardiac cycle;
segmenting the proximal marker, the distal tip marker, the lens marker and the guidewire from the subset of the image frames; and
computing an intersection between the at least two angiogram runs for each of the proximal marker, the distal tip marker, the lens marker and the guidewire in a world coordinate system over time to determine a reference curve as a trajectory of the lens marker in the world coordinate system as a function of time.

US Pat. No. 10,390,887

SYSTEM AND METHOD FOR INTRAOPERATIVE SURGICAL PLANNING

Zimmer, Inc., Warsaw, IN...

1. A method for intraoperative surgical planning, the method comprising:accessing, on a computing device operating an intraoperative surgical planning interface, a first medical image providing a first view of a joint within a surgical site;
receiving, within the intraoperative surgical planning interface, selection of a first component of a modular prosthetic device implanted in the first bone of the joint;
displaying, within the intraoperative surgical planning interface, a graphical representation of the first component of the modular prosthetic device overlaid on the first medical image;
updating the graphical representation of the first component based on receiving, within the intraoperative surgical planning interface, positioning inputs representative of an implant location of the first component relative to landmarks on the first bone visible within the first medical image; and
presenting, within the intraoperative surgical planning interface, a selection interface enabling visualization of additional components of the modular prosthetic device virtually connected to the first component and overlaid on the first medical image;
wherein the first component implanted within the first bone includes a plurality of fiducial marks indicative of position; and
wherein receiving the positioning inputs includes receiving indication of relationship between at least one fiducial mark of the plurality of fiducial marks on the first component and the first bone.

US Pat. No. 10,390,886

IMAGE-BASED PEDICLE SCREW POSITIONING

Siemens Healthcare GmbH, ...

1. One or more non-transitory computer readable media embodying a program of instructions executable by machine to perform operations for pedicle screw positioning, the operations comprising:receiving image data of at least a portion of a spine;
segmenting at least one vertebra of interest in the image data to generate segmentation results;
generating a vertebral distance map based on the segmentation results;
determining two pedicle regions within the segmented vertebra of interest based on the vertebral distance map;
determining one or more safe regions within the segmented vertebra of interest by performing a thresholding algorithm based on the vertebral distance map;
generating two optimal insertion paths within the one or more safe regions, wherein the two optimal insertion paths pass through respective centers of the pedicle regions; and
displaying the two optimal insertion paths for pedicle screw positioning.

US Pat. No. 10,390,885

METHOD AND SYSTEM FOR DETERMINING TREATMENTS BY MODIFYING PATIENT-SPECIFIC GEOMETRICAL MODELS

HeartFlow, Inc., Redwood...

1. A method for planning treatment for arterial stenotic lesions by processing patient-specific images of a patient, comprising:identifying a set of stenotic lesions in a patient's coronary arteries from medical image data of the patient;
generating a plurality of treatment options for the set of stenotic lesions, wherein each of the plurality of treatment options corresponds to a stenting configuration in which one or more of the stenotic lesions are stented;
calculating, for each of the plurality of treatment options, predicted hemodynamic metrics for the set of stenotic lesions resulting from the stenting configuration corresponding to that treatment option; and
recommending a treatment option from the plurality of treatment options based on the predicted hemodynamic metrics for the set of stenotic lesions calculated for each of the plurality of treatment options, and based on a number of stents in the stenting configuration corresponding to each of the plurality of treatment options.

US Pat. No. 10,390,884

METHODS AND TEMPLATES FOR SHAPING PATIENT-SPECIFIC ANATOMICAL-FIXATION IMPLANTS

DePuy Synthes Products, I...

1. A method of determining a shape for an anatomical implant, the method comprising steps of:positioning an anatomical implant template along at least one anatomical body, the anatomical implant template defining first and second opposed terminal ends, and including a flexible body that extends between the first and second opposed terminal ends, the flexible body having an external surface at least partially covered by a protective covering, and an internal surface opposite the external surface, the internal surface defining a channel therethrough that supports at least one sensor therein;
bending the template from a first configuration, whereby the anatomical implant template extends along a first path from the first terminal end to the second terminal end, to a second configuration, whereby the anatomical implant template extends from the first terminal end to the second terminal end along a second path different from the first path, wherein when the anatomical implant template is in the second configuration, the anatomical implant template conforms more closely to a curvature of the at least one anatomical body as compared to when the template is in the first configuration; and
causing the at least one sensor to generate a signal having information from which a shape of the anatomical implant template in the second configuration can be ascertained; and
causing a transmitter supported by the flexible body to wirelessly communicate the signal to a computing device.

US Pat. No. 10,390,883

LASER-DIRECTED MICROCAVITATION

1. A method for the generation, in a medium having a liquid phase, of microcavitation bubbles of maximum volume controlled over at least twice a threshold radiant exposure, comprising:using a laser system comprising a pulse shaping mechanism, generating one or more laser pulses, each laser pulse having a pulse duration between 1 ns and 5000 ns and an energy selected to deliver a radiant exposure sufficient to initiate microcavitation within the medium during the pulse duration of each laser pulse, the pulse shaping mechanism imposing on each laser pulse a tailored amplitude profile over said pulse duration selected to deliver a greater quantity of energy to the medium during an end portion of the pulse duration than during a beginning portion thereof; and
irradiating the medium with the laser pulses.

US Pat. No. 10,390,882

FLOW RATE MONITOR FOR FLUID COOLED MICROWAVE ABLATION PROBE

Covidien LP, Mansfield, ...

1. A microwave ablation system comprising:a power source configured to generate microwave energy;
an antenna assembly coupled to the power source;
a coolant source coupled to the antenna assembly and configured to supply a fluid through a fluid path to the antenna assembly;
a sensor coupled to the fluid path and configured to generate an electrical signal indicative of a flow of the fluid through the fluid path;
a signal processing circuit coupled to the sensor and configured to detect at least one peak of the electrical signal being indicative of an interruption in the flow of the fluid through the fluid path; and
a controller configured to automatically adjust output of the microwave energy from the power source based on the detected peak.

US Pat. No. 10,390,881

COOLED MICROWAVE DENERVATION CATHETER WITH INSERTION FEATURE

Denervx LLC, Maple Grove...

1. A catheter configured to be inserted into a body lumen to create a lesion in tissue spaced from the body lumen while protecting tissue forming and adjacent to a wall of the body lumen from injury, the catheter comprising:a catheter body having at least one fluid passage therein;
a balloon in communication with the at least one fluid passage to receive cooling fluid for inflating the balloon into a shape that surrounds the catheter body and contacts the wall of the body lumen when the catheter is positioned in the body lumen, the cooling fluid having a temperature that is less than basal body temperature;
a microwave antenna carried by the catheter so as to be surrounded by the balloon in the inflated shape of the balloon, the microwave antenna being connectable to a microwave generator to supply power to the microwave antenna to cause microwave energy to be emitted omnidirectionally from the microwave antenna, thereby heating the tissue spaced from the body lumen to a temperature sufficient to cause thermal damage while the tissue forming and adjacent to the wall of the body lumen are maintained at a temperature where thermal damage does not occur by virtue of circulation of cooling fluid in the balloon around the microwave antenna; and
a tip structure located at an end of the catheter body adjacent to and extending distally further than the microwave antenna, the tip structure being configured to receive a guide wire extending through the at least one fluid passage in the catheter body while sealing the at least one fluid passage in the catheter body from leakage.

US Pat. No. 10,390,880

CATHETER WITH IRRIGATED TIP ELECTRODE WITH POROUS SUBSTRATE AND HIGH DENSITY SURFACE MICRO-ELECTRODES

Biosense Webster (Israel)...

1. A catheter comprising:an elongated catheter body;
a distal electrode member distal of the catheter body and having a porous substrate and a plurality of surface electrodes on portions of an outer surface of the porous substrate, the porous substrate having an interior chamber adapted to receive conductive fluid;
a plurality of lead traces on the outer surface of the porous substrate, each of the plurality of lead traces connected to a respective one of the plurality of surface electrodes, at least one of the plurality of lead traces having a portion extending underneath at least one other of the plurality of surface electrodes, the portion of the at least one of the plurality of lead traces extending underneath the at least one other of the plurality of surface electrodes sitting in a groove on the outer surface of the porous substrate; and
a chamber lead wire having a distal portion extending into the interior chamber, the chamber lead wire adapted to electrify the conductive fluid in the interior chamber,
the porous substrate being configured to pass the conductive fluid from the interior chamber to the outer surface of the porous substrate.

US Pat. No. 10,390,879

DEVICES AND METHODS FOR ABLATION OF TISSUE

Mayo Foundation for Medic...

1. A catheter-based medical device for treating a tissue, the device comprising:an elongate catheter shaft including a liquid delivery lumen therethrough;
a balloon device disposed at a distal end portion of said catheter shaft, said balloon device comprising a bulbous-shaped proximal portion and a generally cylindrical-shaped distal portion when said balloon is inflated, said bulbous-shaped proximal portion in fluid communication with said generally cylindrical-shaped distal portion, said balloon device comprising an outer surface and an inner surface, said inner surface defining an interior space of said balloon device, said balloon device in fluid communication with said liquid delivery lumen, said balloon device comprising a porous or microporous material that is arranged to transmit a liquid through said porous or microporous material;
one or more electrodes that are disposed on or within said balloon device and are arranged to deliver energy to said tissue; and
a filter device that is reconfigurable between a collapsed low-profile delivery configuration and a deployed configuration in which said filter device is radially expanded in comparison to said collapsed low-profile delivery configuration, wherein said bulbous-shaped proximal portion of said balloon device is inside said filter device while said filter device is configured in said deployed configuration.

US Pat. No. 10,390,878

MEDICAL DEVICE AND MEDICAL SYSTEM

OLYMPUS CORPORATION, Tok...

1. A medical device comprising:an insertion portion which is capable of being inserted into a body; and
a driving mechanism which is coupled to the insertion portion,
wherein the insertion portion includes:
a treatment portion which is configured to perform a treatment on a treatment target portion;
a joint portion which is configured to be capable of supporting the treatment portion and changing a direction of the treatment portion;
a storage portion which is configured in the joint portion and capable of internally accommodating the treatment portion; and
a driving force transmission portion which is connected to the joint portion and configured to transmit a driving force for changing the direction of the treatment portion to the joint portion,
wherein the driving mechanism includes a driving force generation portion which is configured to generate the driving force connected to the driving force transmission portion,
wherein the treatment portion enters and exits the storage portion by the driving force transmitted from the driving force generation portion to the joint portion through the driving force transmission portion,
wherein the treatment portion includes an incision electrode which is configured to receive a supply of a high-frequency current to incise living tissue,
wherein the joint portion includes a switching mechanism which is configured to switch a conductive state of the high-frequency current for the incision electrode,
wherein the insertion portion includes a power supplying cable which is connected to the switching mechanism and from which the high-frequency current is applied,
wherein the driving mechanism includes a plug which is connected to the power supplying cable and connectable to a high-frequency power supply device, and
wherein the switching mechanism cuts off a current applied to the power supplying cable and the incision electrode when the incision electrode is positioned inside the storage portion, and electrically connects the power supplying cable and the incision electrode when the incision electrode is positioned outside the storage portion.

US Pat. No. 10,390,877

SYSTEMS AND METHODS FOR TREATING BACK PAIN

Relievant Medsystems, Inc...

1. A method for treating back pain associated with a vertebral body of a patient, comprising:imaging a vertebral body to generate one or more images of the vertebral body;
locating, based on said images, a portion of a sinuvertebral nerve within an epidural space associated with the vertebral body;
identifying one or more nerve branches associated with the vertebral body and emanating at a first end at a junction with the sinuvertebral nerve at a location external to the vertebral body and that course medially from the junction under a posterior longitudinal ligament,
percutaneously guiding a delivery assembly to the location external to the vertebral body,
wherein the delivery assembly comprises at least one lumen for advancing an imaging device and for advancing a treatment device;
isolating the one or more nerve branches for treatment,
wherein isolating the one or more nerve branches comprises verifying that the one or more nerve branches course under the posterior longitudinal ligament;
delivering the treatment device to the external location via the delivery assembly; and
denervating the one or more isolated nerve branches at a position at or near the junction with the sinuvertebral nerve,
wherein denervating the one or more isolated nerve branches comprises operating the treatment device at the position at or near the junction with the sinuvertebral nerve.

US Pat. No. 10,390,876

PLANAR TRANSFORMERS HAVING REDUCED TERMINATION LOSSES

COVIDIEN LP, Mansfield, ...

1. An electrosurgical generator for generating electrosurgical energy, the generator including a planar transformer, the planar transformer comprising:a plurality of circuit layers stacked together in a first direction, the plurality of circuit layers including at least one terminal for outputting electrosurgical energy, and further including a first circuit layer and a second circuit layer, the first and second circuit layers each including an electrically conductive trace forming at least one of primary windings of the planar transformer, a first termination portion, and a second termination portion, the first termination portion and the second termination portion defining a gap therebetween,
wherein the plurality of stacked circuit layers includes a means for spreading current flowing through the first and second termination portions of the first and second circuit layers,
wherein the plurality of stacked circuit layers further includes a plurality of secondary circuit layers different from the first and second circuit layers, a portion of each having an electrically conductive trace that forms a grounded portion coupled to ground and a second portion of each having an electrically conductive trace that forms a secondary winding of the planar transformer, and
wherein the first and second gaps of the first and second circuit layers are immediately adjacent to the grounded portion of a corresponding secondary circuit layer along the first direction.

US Pat. No. 10,390,875

SYSTEM AND APPARATUS FOR AUTOMATIC ACTIVATION USING RADIO FREQUENCY SENSOR

I.C. Medical, Inc., Phoe...

1. A system for automatic smoke evacuation comprising:a surgical instrument capable of producing a radiofrequency during its operation;
a smoke evacuation unit capable of evacuating at least one of smoke and debris through a smoke evacuation channel;
a wireless radiofrequency sensor and transmitter device that is both separate from and not connected to the smoke evacuation unit and separate from and not contained within the surgical instrument, wherein the wireless radiofrequency sensor and transmitter device is capable of receiving a transmitter device signal from the surgical instrument and transmitting a signal;
a radiofrequency receiver connected to, or incorporated within, the smoke evacuation unit that is capable of receiving the transmitter device signal transmitted from the wireless radiofrequency sensor and transmitter device,
wherein the wireless radiofrequency sensor and transmitter device comprises a plurality of radiofrequency sensor components and a plurality of radiofrequency transmitter components, and
wherein the plurality of radiofrequency sensor components includes a single transistor, a double transistor, and an optocoupler wherein the single transistor and the double transistor are in sequence with one another and the optocoupler is in sequence with the double transistor.

US Pat. No. 10,390,874

METHODS, SYSTEMS, AND APPARATUSES FOR TISSUE ABLATION USING ELECTROLYSIS AND PERMEABILIZATION

RM2 TECHNOLOGY LLC, Trab...

1. A method for tissue ablation, the method comprising:permeabilizing cell membranes in the tissue; and
performing electrolysis to deliver electrons to and remove electrons from the tissue thereby generating products of electrolysis in the tissue, wherein said products of electrolysis are toxic to cells in the tissue.

US Pat. No. 10,390,873

SYSTEMS AND METHODS FOR PROSTATE TREATMENT

Boston Scientific Scimed,...

1. A method for treating benign prostatic hyperplasia (BPH), comprising:introducing an energy delivery member transurethrally into a transition zone tissue adjacent a patient's prostatic urethra; and
injecting a condensable vapor media from the energy delivery member into the transition zone tissue at a depth of less than 12 mm outward from the patient's prostatic urethra so as to confine the condensable vapor media in the transition zone tissue and to ablate the transition zone tissue adjacent to and less than 12 mm outward from the prostatic urethra, wherein the condensable vapor media is configured to apply energy ranging from 1 to 40 cal/sec to the transition zone tissue.

US Pat. No. 10,390,872

MULTIFUNCTIONAL ABLATION DEVICE

Medtronic CryoCath LP, T...

1. A method of treating cardiac tissue, the method comprising:positioning an expandable element of a medical device proximate a pulmonary vein and expanding the expandable element in the pulmonary vein to substantially occlude the pulmonary vein;
positioning a substantially linear thermal segment of the medical device proximate an atrial wall, the thermal segment being more flexible than at least one medical device segment adjacent to the thermal segment;
applying a compressive force from a proximal portion of the medical device to the thermal segment, the compressive force causing the thermal segment to deflect towards the atrial wall; and
circulating cryogenic fluid through a first fluid flow path in fluid communication with the expandable element to ablate the pulmonary vein.

US Pat. No. 10,390,871

CRYONEEDLE

Galil Medical Inc., Arde...

1. A cryoneedle comprising:an outer tube having a distal section and a longitudinal axis;
a gas supply line positioned within the outer tube, the gas supply line configured to supply a cryogas for forming an ice ball on an outer surface of the outer tube over the distal section, the gas supply line having a cryogas outlet;
an expansion chamber located within the distal section such that the gas supply line terminates in the expansion chamber, the cryogas outlet being positioned in the expansion chamber;
an electrical resistance heater configured to heat tissue, when current is supplied thereto, the electrical resistance heater comprising a wire wound around the gas supply line into helical coils, the electrical resistance heater being located within the distal section of the outer tube;
a heat exchange helix contacting an inner surface of the outer tube, the heat exchange helix extending longitudinally in a distal direction past the cryogas outlet in the distal section; and
a return gas flow lumen defined annularly between the heat exchange helix and the gas supply line adapted to carry the cryogas from the expansion chamber along a return flow path,
the heat exchange helix adapted to provide generally uniform rate of heat transfer in the distal section such that the ice ball formed on the outer surface of the outer tube is generally symmetric in shape along the longitudinal axis of the outer tube.

US Pat. No. 10,390,869

TECHNIQUES AND INSTRUMENTS FOR PLACEMENT OF ORTHOPEDIC IMPLANTS RELATIVE TO BONE FEATURES

McGinley Engineered Solut...

1. A surgical instrument for use in placement of orthopedic implants relative to a bone of a patient, comprising:an instrument body having a first cannulated passage extending continuously through the instrument body along a working axis of the instrument, the first cannulated passage being sized to receive and extend about at least a portion of an orthopedic implant within the cannulated passage;
a chuck engageable with the orthopedic implant to selectively engage the orthopedic implant to restrict axial movement of the orthopedic implant relative to the chuck along the working axis in the absence of an external force being applied to the chuck, wherein the chuck comprises a second cannulated passage axially aligned along the working axis, and wherein the chuck comprises a plurality of spherical jaw members that are each disposed within a respective helical channel comprising a constrictive helical cam surface such that at least a portion of each of the spherical jaw members at least partially extends into the second cannulated passage to engage the orthopedic implant, the constrictive helical cam surface being normally biased into engagement with the plurality of spherical jaw members to dispose the spherical jaw members toward the working axis to directly engage the orthopedic implant;
a drive engaged with the chuck to impart rotational motion of the chuck about the working axis including rotational motion of the helical channels and the spherical jaw members such that the rotational motion of the chuck relative to the orthopedic implant urges the plurality of spherical jaw members of the chuck into engagement with the orthopedic implant; and
a measurement system having a displacement sensing arm moveable in a direction parallel to the working axis to measure advancement of the orthopedic implant driven by the instrument into the bone of the patient along the working axis.

US Pat. No. 10,390,867

BONE PLATE SYSTEM AND METHOD

Biomet C.V., Warsaw, IN ...

1. A bone plate system internally fixating a fractured bone of a patient, the system comprising:a bone plate including a head portion and a shaft portion having a longitudinal axis, the head portion being wider than the shaft portion, the bone plate further including:
a plurality of threaded, locking bone fastener apertures defined in the shaft portion and defining a respective plurality of threaded aperture axes; and
a plurality of non-threaded, non-locking bone fastener apertures defined in the shaft portion, aligned on the longitudinal axis, and defining a respective plurality of non-threaded aperture axes,
each non-threaded aperture axis being angled between about ten degrees and about thirty degrees with respect to each threaded aperture axis,
each of the plurality of non-threaded bone fastener apertures being paired together with at least one of the plurality of the threaded bone fastener apertures to form a plurality of discrete aperture clusters,
a first aperture cluster of the plurality of discrete aperture clusters being positioned about a proximal end of the shaft portion,
a second aperture cluster of the plurality of discrete aperture clusters being positioned about a distal end of the shaft portion,
the first and second aperture clusters including respective threaded, locking bone fastener apertures that are positioned on laterally opposed sides of the longitudinal axis; and
a plurality of bone fasteners,
each of the plurality of bone fasteners comprising a shaft and a head,
each head being dimensioned and configured to threadedly engage each of the plurality of threaded, locking bone fastener apertures to provide a fixed angle locking construct,
each head also being dimensioned and configured to directly engage each of the plurality of non-threaded, non-locking bone fastener apertures to provide a polyaxial compressive construct.

US Pat. No. 10,390,866

VARIABLE ANGLE LOCKING IMPLANT

1. A variable angle locking implant comprising:a bone plate having a lower surface;
an upper surface; and
at least one opening extending from the lower surface to the upper surface along an axis, the at least one opening having an inner surface consisting of a plurality of upper fins and a plurality of lower fins, the plurality of upper fins being circumferentially disposed about the inner surface, the plurality of circumferentially disposed upper fins defining an upper, circumferential edge including a series of concave and convex surfaces, the plurality of lower fins being circumferentially disposed about the inner surface, the plurality of circumferentially disposed lower fins defining a lower, circumferential edge including a series of concave and convex surfaces, wherein the plurality of upper fins are positioned closer to the upper surface of the bone plate and the plurality of lower fins are positioned closer to the lower surface of the bone plate; and
wherein at least one of the plurality of upper fins and the plurality of lower fins cooperate with a head of a bone fastener; and
wherein the plurality of upper and lower fins each have a tapered surface extending from the inner surface of the at least one opening to a terminal end of the fin.

US Pat. No. 10,390,865

ORTHOPEDIC LOCKING SCREW FOR AN ORTHOPEDIC FASTENING SYSTEM AND METHOD OF SECURING AN ORTHOPEDIC LOCKING SCREW

Stryker European Holdings...

1. An orthopedic fastening system, comprising:an orthopedic implant comprising a bore; and
an orthopedic locking screw configured to be retained inside the bore, the orthopedic locking screw comprising:
a shaft extending along an axis between a first and a second end, the first end sized to be received in the bore;
a drive member disposed at the second end;
a casing secured to and rotationally fixed around an outer surface of the shaft in a non-secured state of the screw, wherein the casing is formed of a plastically deformable material, the casing having a first end proximate the first end of the shaft and a second end proximate the second end of the shaft; and
a forward external thread disposed on the shaft between the first end of the casing and the first end of the shaft,
wherein the casing has an outer cross-sectional width (W1) that is larger than a smallest inside cross-sectional width of the bore and forms a press-fit pressure against the bore when operably disposed in the bore, and
wherein the casing comprises a deformable thread disposed along an outer surface of the casing, wherein the deformable thread is an external thread that is configured to engage an internal thread feature of the bore.

US Pat. No. 10,390,863

ROD CONNECTOR

KYUNGPOOK NATIONAL UNIVER...

1. A rod connector used in screw fixation to connect different rods, the rod connector comprising:a latch including a latch section configured to hold a first rod, and a pass-through section having a through-hole;
a support assembly including an up-and-down movement section configured to move up and down through the through-hole, and a support section connected to the up-and-down movement section and having a support groove to support a second rod; and
a fixing screw configured to approach the up-and-down movement section through a screw hole disposed in the latch,
a fixing piece configured to hold and fix the support assembly at the predetermined height by a close contact between the fixing piece and the up-and-down movement section by a pushing force of the fixing screw.

US Pat. No. 10,390,862

SPINAL CORRECTION SYSTEM AND METHOD

Warsaw Orthopedic, Inc., ...

1. A spinal construct comprising:a longitudinal element;
a first arm connected with the longitudinal element;
a first body connected with the first arm such that the first body is rotatable relative to the first arm, the first arm including a lock to fix the first body relative to the first arm, the lock of the first body including a collar and a shaft that support the first arm, the collar defining an opening and the shaft defining an opening, the openings being aligned to support the first arm;
a second arm connected with the longitudinal element and axially translatable relative to the first arm, the second arm including a housing;
a second body connected with the second arm such that the second body is rotatable relative to the second arm, the second arm including a lock to fix the second body relative to the second arm; and
a locking element pivotably coupled to the housing and configured to move between a first orientation in which the second arm is translatable along the longitudinal element and a second orientation in which the second arm is prevented from translating along the longitudinal element.

US Pat. No. 10,390,861

SPINAL STABILIZATION DEVICE, SYSTEM, AND METHOD OF USE

K2M, Inc., Leesburg, VA ...

1. A spinal stabilization device comprising:a rod receiving member defining a first throughhole, a collet recess aligned with the first throughhole, and a rod receiving slot offset from the first throughhole;
a collet insertable into the collet recess of the rod receiving member, the collet defining an aperture, a plug recess aligned with the aperture, and a wall portion, the wall portion and the rod receiving slot cooperatively defining a rod securement region configured to selectively fix a spinal rod therein, the collet transitionable between a first diameter, wherein the rod securement region defines a first diameter, and a second, larger diameter, wherein the rod securement region defines a second, smaller diameter;
a plug insertable within the plug recess of the collet and configured to transition the collet between the first and second diameters, such that the collet is in the first diameter when the plug is removed and the collet is in the second diameter when the plug is inserted; and
a first bone screw including a head portion and a threaded portion, the threaded portion insertable through the first throughhole of the rod receiving member and the aperture of the collet.

US Pat. No. 10,390,860

INTERNAL PEDICLE INSULATOR

CHAP-MED, INC., Destin, ...

1. A method for stabilizing a surgical fixture comprising:inserting an implant into tissue, the implant comprising:
a non-continuous cylindrical wall defining an interior cavity and having a first end and a second end;
a first segment of the cylindrical wall comprising a smooth exterior surface;
and
a second segment of the cylindrical wall comprising a rough exterior surface, wherein:
the first segment of the cylindrical wall is of a greater thickness than the second segment of the cylindrical wall; and
a portion of the second segment of the cylindrical wall overlaps a portion of the first segment of the cylindrical wall, extending into the interior cavity; and
driving a distal end of a fixture into tissue into which the implant is inserted.

US Pat. No. 10,390,859

SYSTEM FOR CORRECTING BONES

UMC UTRECHT HOLDING B.V.,...

1. A system for correcting bones, comprising:at least a first pin which is configured to be connected to the bone at a first location;
at least a second pin which is configured to be connected to the bone at a second location at a distance from the first location;
a fixation member which is coupled rigidly to the first and second pins for the purpose of fixing the mutual distance between the pins during a hardening phase, and which is coupled flexibly to the first and the second pins during a correction phase;
at least a first annular fixation member which is connected to the first pin and at least a second annular fixation member which is connected to the second pin so that the mutual distance and/or orientation between the first and second annular fixation members can be adjusted while the fixation member remains coupled to the first pin and the second pin during the correction phase,
wherein the fixation member is configured to remain attached to the first pin and the second pin when the first annular fixation member and the second annular fixation member are removed during the hardening phase, and
wherein the first pin and the second pin are configured to remain connected to the bone at the first location and the second location, respectively, throughout the correction phase and the hardening phase.

US Pat. No. 10,390,858

POWERED SURGICAL DEVICE WITH SPEED AND CURRENT DERIVATIVE MOTOR SHUT OFF

Covidien LP, Mansfield, ...

1. A surgical instrument, comprising:an end effector;
a power source;
a motor coupled to the power source, the motor configured to actuate the end effector;
a motor control circuit configured to measure a current draw of the motor and an angular velocity of the motor; and
a controller operatively coupled to the motor and configured to:
control the motor based on a current draw of the motor and an angular velocity of the motor;
calculate an instantaneous rate of change of each of the current draw of the motor and the angular velocity of the motor; and
determine that the motor reached a mechanical limit based on the instantaneous rate of change of the current draw of the motor exceeding a first threshold and the instantaneous rate of change of the angular velocity of the motor exceeding a second threshold.

US Pat. No. 10,390,857

AIRWAY IMPLANT DELIVERY DEVICE

The Snoring Center, Dall...

1. A delivery tool for delivering a plurality of implants into a soft palate of a patient for treatment of sleep breathing disorders, the delivery tool comprising:a curved penetrating cannula with a proximal end and a distal tip, wherein a curve of the penetrating cannula approximates a curvature of the soft palate, the distal tip shaped for penetration into the soft palate through a small penetration wound, the penetrating cannula having a plurality of depth markings to provide a visual indication of penetration depth, wherein the plurality of depth markings includes a halfway depth marking that is based on a length of one of the plurality of implants,
a cylindrical cartridge having a plurality of longitudinal bores wherein at least one of the longitudinal bores is adapted to align with the proximal end of the penetrating cannula, and wherein the plurality of longitudinal bores are positioned radially about a longitudinal axis of the cylindrical cartridge,
the plurality of implants, where each implant is positioned within a respective longitudinal bore of the plurality of bores and each implant comprises flexible, fibrous, bio-compatible material,
an obturator sized to fit within the penetrating cannula, the obturator adapted for pushing one of the plurality of implants through the at least one of the longitudinal bores and through the penetrating cannula such that the longitudinal dimension of the implant is aligned with an axis of the penetrating cannula,
an actuator having a distal end coupled to the proximal end of the obturator and a proximal end of the actuator for interacting with a user, and
a deployment indicator positioned to indicate when the obturator is in a halfway deployment position, wherein the halfway deployment position corresponds to the halfway depth marking and indicates when the penetrating cannula is to be withdrawn to the halfway depth marking during delivery of one of the plurality of implants.

US Pat. No. 10,390,856

SURGICAL IMPLANTATION INSTRUMENT

MINIPUMPS, LLC, Pasadena...

1. An instrument facilitating surgical implantation of an implantable device having two opposed surface portions at least one of which has a curved surface contour, the instrument comprising:first and second forceps arms each having first and second ends, the arms being joined at the first ends thereof and arranged to oppose but permit resisted compression of the arms toward each other into a closed position from an open position, wherein compression of the arms toward each other into the closed position forces the second ends of the arms toward each other;
a first-arm head member, having a first length defined by a distal end and a proximal end thereof, located at the second end of the first arm; and
a second-arm head member, having a second length defined by a distal end and a proximal end thereof, located at the second end of the second arm,
wherein:
(i) the head members are flared outwardly so as to be angled away from each other along the entire first and second lengths thereof at least in the open position relative to an axis running between and coplanar with the arms,
(ii) each of the head members defines an interior surface, the interior surfaces being opposed to each other and differently shaped to releasably engage the implantable device without damage thereto upon compression of the arms into the closed position,
(iii) the interior surface of at least one of the head members has a curved portion complementary to the curved surface contour of the implantable device whereby closure of the arms causes the head members to opposedly engage the surface contour of the implantable device to prevent release thereof from the instrument in the closed position, and
(iv) the differently shaped interior surfaces mate with different surface contours of the implantable device.

US Pat. No. 10,390,855

SURGICAL FORCEPS

COVIDIEN LP, Mansfield, ...

1. A surgical instrument, comprising:an end effector assembly; and
a closure beam configured to operably engage the end effector assembly to transition the end effector assembly between a spaced-apart condition, a first approximated condition, and a second approximated condition, the closure beam including:
first and second spaced-apart transverse beams each defining a length; and
a perpendicular beam extending between and interconnecting the first and second spaced-apart transverse beams along a portion of the lengths thereof,
the closure beam defining:
a proximal portion, wherein the first and second spaced-apart transverse beams are spaced-apart a first distance;
a distal portion, wherein the first and second spaced-apart transverse beams are spaced-apart a second distance greater than the first distance; and
an intermediate portion extending between and interconnecting the proximal and distal portions, wherein the first and second spaced-apart transverse beams define parallel configurations in the distal and proximal portions of the closure beam.

US Pat. No. 10,390,854

ROTATABLE MEDICAL DEVICE

Boston Scientific Scimed,...

1. A medical device, comprising:a tubular member having a lumen;
a shaft extending through the lumen; and
a handle at a proximal end of the tubular member, wherein the handle includes:
a base coupled to the shaft,
a first hub member coupled to the base,
a second hub member coupled to the first hub member, and
a cap coupled to the second hub member,
wherein each of the first hub member and the second hub member extends into a cavity defined by the cap, and
wherein engagement between the cap and the second hub member, due to movement of the cap onto the second hub member, compresses the second hub member onto the first hub member, causing an increase in frictional engagement between the second hub member and the first hub member.

US Pat. No. 10,390,853

ROBOTICALLY CONTROLLING MECHANICAL ADVANTAGE GRIPPING

Covidien LP, Mansfield, ...

1. An end effector of a surgical tool, the end effector comprising:a housing having proximal and distal ends, the housing defining a longitudinal axis that extends through the proximal and distal ends;
a jaw support shaft mounted to the housing and defining a pivot axis that extends therethrough;
a pair of jaw members supported on the jaw support shaft and being pivotable about the pivot axis, each of the pair of jaw members defining a support shaft slot therethrough and including a pulley pin and a jaw pin extending therefrom, each of the pair of jaw members defining a jaw pin slot adapted to receive an opposing one of the jaw pins of the pair of jaw members; and
a pair of cam pulleys mounted to the jaw support shaft and coupled to the pair of jaw members, the pair of cam pulleys being rotatable about the pivot axis to pivot the pair of jaw members about the jaw support shaft, the pair of cam pulleys movable relative to the pair of jaw members.

US Pat. No. 10,390,852

MINIMALLY INVASIVE SURGICAL ASSEMBLY AND METHODS

TELEFLEX MEDICAL INCORPOR...

1. A surgical device, comprising:a) an elongated needle body defining an interior lumen extending longitudinally therethrough, the elongated needle body having a sharpened distal tip portion;
b) an assembly operatively associated with the interior lumen of the elongated needle body, the assembly having:
i) a shaft having an outer surface profile corresponding to an inner surface of the interior lumen of the elongated needle body; and
ii) a pair of arms extending distally from the shaft, each of the pair of arms comprising a rod and a grasper, wherein the graspers are biased radially outward from the longitudinal axis of the shaft, and one arm of the pair of arms is in a fixed axial alignment with the sharpened distal tip portion of the elongated needle body such that the pair of arms act as an obturator relative to the sharpened distal tip portion of the elongated needle body to guard the elongated needle body from causing accidental needle tip trauma; and
c) a handle portion operatively attached to a proximal end portions of both the elongated needle body and the shaft such that the elongated needle body and the shaft can be rotated independent of the handle portion, the handle portion further configured and adapted to advance and retract the elongated needle body over the pair of arms and the shaft, the elongated needle body being biased towards a retracted position to further guard the elongated needle body from accidental needle trauma,
wherein the pair of arms are formed as electrically isolated conductors, and
wherein the rods are each encircled by a plastic overwrap, the plastic overwrap having a shape corresponding to a respective outer surface of the rods to maintain the fixed axial alignment.

US Pat. No. 10,390,851

RETRIEVAL DEVICES AND RELATED METHODS OF USE

Boston Scientific Scimed,...

1. A retrieval device having a contracted state and an expanded state, comprising:a sheath;
at least three support members each having a first portion with a first cross-sectional shape being distal to a second portion with a second cross-sectional shape different from the first cross-sectional shape, a proximal end fixed to the sheath, and a distal end movable relative to the sheath; and
at least three movable members each having a pair of ends movable relative to the support members, each movable member extending through a lumen of one support member of the at least three support members and through a lumen of a different support member of the at least three support members, wherein the first portion is sized to permit a plurality of degrees of freedom to each movable member; and
wherein the second portion is sized to permit a reduced number of degrees of freedom to each movable member so as to prevent a first movable member from twisting about another moveable member of the at least three moveable members.