US Pat. No. 10,213,310

DUAL MODULUS HIP STEM AND METHOD OF MAKING THE SAME

DePuy Synthes Products, I...

1. A method of manufacturing an orthopaedic prosthesis for a patient, comprising:producing a shell from a metallic foam material having a first elastic modulus,
producing a stem core from a metallic material having a second elastic modulus greater than the first elastic modulus, the stem core including a neck configured to receive a femoral head component, and
securing the shell to the stem core such that (i) a sheath of the shell is positioned over a proximal segment of the stem core, and (ii) a cover layer of the shell extends along a lateral surface of a distal segment of the stem core, wherein the cover layer has a body that extends distally from a proximal end attached to the sheath to a distal tip of the stem core, the body having a first body thickness at the proximal end that is greater than a second body thickness at the distal tip,
wherein when the orthopaedic prosthesis is viewed in a transverse plane extending through the cover layer and the distal segment of the stem core, (i) the cover layer defines a first cross-sectional area, (ii) the cover layer and the distal segment of the stem core define a second cross-sectional area, and (iii) a ratio of the first cross-sectional area to the second cross-sectional area is greater than 0.30.

US Pat. No. 10,213,309

TISSUE INTEGRATION DESIGN FOR SEAMLESS IMPLANT FIXATION

1. A musculo-skeletal implant comprising a first end having a vertebral-contacting surface to contact a first vertebra, a second end having a vertebral-contacting surface to contact a second vertebra, a longitudinal axis extending through respective centers of the first and second ends, an outer fenestrated wall extending from the first end to the second end, and a monolithic inner fenestrated wall inside the outer fenestrated wall and extending entirely around the longitudinal axis to laterally surround a central hollow cavity that extends through the first and second ends,wherein an open space extends through the first and second ends and between the inner fenestrated wall and the outer fenestrated wall from the first end to the second end, wherein fenestrations of the outer fenestrated wall extend toward the inner fenestrated wall and into the open space, wherein fenestrations of the inner fenestrated wall are arranged laterally around the longitudinal axis, wherein the open space extends through the first end to an outside of the implant via a plurality of individual openings each forming a shape with a different number of sides than at least one of the fenestrations of the inner or outer fenestrated walls, and wherein at least one linear pathway extends unobstructed from the hollow cavity through respective fenestrations of the inner and outer fenestrated walls to the outside of the implant,
wherein the inner fenestrated wall is integrally connected with the outer fenestrated wall by a plurality of interconnecting members, wherein first ones of the interconnecting members located at an end face at the first end at least partially define the individual openings and have at least a portion that faces away from all other parts of the implant, while another one of the interconnecting members is spaced apart from the first and second ends,
wherein at least two of the interconnecting members are aligned laterally around the longitudinal axis, and wherein a distance between the inner and outer fenestrated walls at one of the interconnecting members is substantially the same as a distance between the inner and outer fenestrated walls at a location between two laterally adjacent ones of the interconnecting members, and
wherein the inner and outer fenestrated walls comprise a non-biodegradable material and are permanently fixable with a host body tissue by integration as a structural support of the inner and outer fenestrated walls therewith.

US Pat. No. 10,213,308

PROSTHESIS INCLUDING BALL AND SOCKET ARRANGEMENT

Aptis Medical, LLC, Glen...

1. A prosthesis for replacing a mammalian joint, comprising:a first body, including a ball mounted on a shaft;
a second body, including a base and a cap which secures to the base, said base and cap each having an inner surface and an outer surface, with the inner surfaces of the base and cap together defining a socket which receives and traps the ball and supports the ball for rotation relative to the second body;
wherein one of said inner and outer surfaces of said base defines a first groove, and said cap has a first leg projecting in a first direction and being received in said first groove by sliding into said first groove in said first direction;
and further comprising a second leg on one of said base and said cap and a second groove on the other of said base and said cap, said second leg and second groove lying parallel to and directly opposite said first leg and said first groove, wherein said second leg slides into and is received in said second groove when said first leg slides into and is received in said first groove;
wherein said first leg defines a first leg opening having an axis extending in a direction that is cross-wise to the first direction, said second leg defines a second leg opening coaxial with the first leg opening, and said base defines a base opening which is aligned with said first leg opening when the base and cap are assembled together; and
a pin received in said first leg opening, said second leg opening, and said base opening and extending in the cross-wise direction to secure the cap and base together so that an attempt to slide the cap and base apart from each other in the first direction applies shear forces to the pin; and
means for preventing the first leg from moving outwardly away from the first groove in the cross-wise direction when the first leg is received in the first groove;
wherein said means for preventing the first leg from moving outwardly away from the first groove includes at least a portion of said base contacting the outer surface of the first leg.

US Pat. No. 10,213,307

TRANSCATHETER VALVE PROSTHESIS HAVING AN EXTERNAL SKIRT FOR SEALING AND PREVENTING PARAVALVULAR LEAKAGE

MEDTRONIC VASCULAR, INC.,...

1. A transcatheter valve prosthesis comprising:a tubular stent including a plurality of openings and having a compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve;
a skirt coupled to the tubular stent, the skirt including only a single layer of skirt material, a first portion of the skirt being attached to and covering an inner circumferential surface of the tubular stent and a second portion of the skirt being attached to and covering an outer circumferential surface of an inflow end of the tubular stent, wherein the skirt is continuous from the first portion to the second portion such that the first and second portions do not overlap and only the single layer of skirt material covers the tubular stent at any longitudinal position thereof and wherein the single layer of skirt material includes a plurality of cuts therein that are positioned to permit the skirt to extend from the inner circumferential surface to the outer circumferential surface of the tubular stent through the plurality of openings; and
a prosthetic valve component disposed within and secured to the first portion of the skirt.

US Pat. No. 10,213,306

MINIMALLY INVASIVE HEART VALVE REPAIR IN A BEATING HEART

NeoChord, Inc., St. Loui...

1. A method of minimally invasively performing an edge to edge heart valve leaflet repair on a beating heart of a patient, comprising:accessing an interior of a beating heart of a patient minimally invasively;
inserting one or more sutures into each of a first valve leaflet and a second valve leaflet of a heart valve in the beating heart of the patient, each suture having a pair of suture ends;
providing a plurality of suture pairs, each suture pair including one of the pair of suture ends of a suture inserted through the first valve leaflet and one of the pair of suture ends of a suture inserted through the second valve leaflet;
advancing one or more tourniquet tubes over the suture pairs towards the heart valve such that the sutures are drawn into a coaptation tension in which the first valve leaflet and the second valve leaflet are in a coapted position;
securing the sutures at the coaptation tension;
withdrawing the one or more tourniquet tubes from the suture ends after securing the sutures; and
anchoring the suture ends at a wall of the heart with the sutures in the coaptation tension,
wherein securing the sutures at the coaptation tension includes:
securing the one or more tourniquet tubes with respect to the suture pairs with the sutures in the coaptation tension;
advancing a suture loop of a ligature suture along the one or more tourniquet tubes to the first valve leaflet and the second valve leaflet; and
securing the suture loop around the sutures with the sutures in the coaptation tension.

US Pat. No. 10,213,305

DEVICE AND METHOD FOR IMPROVING HEART VALVE FUNCTION

Edwards Lifesciences AG, ...

1. A blood-flow controlling device for treating a mitral or tricuspid valve in need thereof, the device comprising:a blood-flow blocking portion comprising an elongate structure with a substantially cylindrical portion, a portion of the blood-flow blocking portion disposable between leaflets of a native mitral or tricuspid valve and fillable with blood;
a flexible, elongate body portion passing inside of the blood-flow blocking portion, the blood-flow blocking portion slidable up and down the body portion;
an anchor portion disposed on a distal end of the elongate body portion, the anchor portion engageable with heart tissue at or adjacent a heart apex, the anchor portion comprising a tubular body and a plurality of pointed, elongated prongs emanating from a distal end of the tubular body, the plurality of elongated prongs self-expandable from a compressed configuration, in which the plurality of elongated prongs extend distally, and an expanded configuration, in which the plurality of elongated prongs are deflected radially outward relative to a center of the tubular body;
an anchor delivery catheter for delivering the anchor portion having a distal end sheath that maintains the plurality of elongated prongs in the compressed configuration; and
a locking catheter slidable along the elongate body portion,
wherein the locking catheter is operable to lock the blood-flow blocking portion to the elongate body portion, preventing sliding therebetween.

US Pat. No. 10,213,304

APPARATUS, SYSTEM, AND METHOD FOR TREATING A REGURGITANT HEART VALVE

THE CLEVELAND CLINIC FOUN...

1. A method for treating regurgitation of blood through a diseased heart valve having at least two leaflets, said method comprising the steps of:providing a system comprising an apparatus and an adjustment member, the apparatus including a lollipop-shaped body member having a proximal end portion, a distal end portion, and an intermediate portion extending between the distal end portions, the intermediate portion including an expandable occluding member having an adjustable diameter, the proximal end portion being physically connected to the occluding member and including a connecting mechanism that is operably connected to the adjustment member, and the distal end portion including an anchoring member;
securing the anchoring member in a heart chamber containing the heart valve;
operating the adjustment member so that the anchoring member is securely positioned within heart tissue associated with the diseased heart valve; and
operating the adjustment member to increase or decrease the diameter of the occluding member so that at least one of the diseased heart valve leaflets coapts with the occluding member during the cardiac cycle;
wherein after the anchoring member is secured in the heart chamber, blood is permitted to flow through at least a portion of the occluding member.

US Pat. No. 10,213,303

RAPID DEPLOYMENT ARTIFICIAL CHORDAE TENDINAE SYSTEM

On-X Life Technologies, I...

1. An artificial chordae tendineae kit comprising:a hollow first needle including a first proximal end portion having a first proximal aperture, a first distal end portion having a first distal aperture, and a first middle portion coupling the first proximal end portion to the first distal end portion;
a flexible first chord coupled to both a first proximal anchor and a first distal anchor;
wherein the first proximal end portion includes a first proximal inner diameter directly adjacent the first proximal aperture, the first distal end portion includes a first distal inner diameter directly adjacent the first distal aperture, the first middle portion includes a first narrowed portion with a first middle inner diameter that is less than either of the first proximal inner diameter and the first distal inner diameter;
wherein the first chord, the first proximal anchor, and the first distal anchor are all included within the first needle with the first distal anchor distal to the first narrowed portion and the first proximal anchor proximal to the first narrowed portion;
wherein the first needle includes a long axis, the first chord includes a long axis, the first proximal anchor includes a long axis, and the first distal anchor includes a long axis;
wherein the long axes of the first proximal and distal anchors are substantially parallel to the long axis of the first needle when the first chord is included within the first needle;
wherein the first proximal and distal anchors are each configured to rotate when deployed from the first needle such that the long axes of the first proximal and distal anchors are each nonparallel to the long axis of the first chord;
wherein the first proximal anchor is deformable and configured to deform to slide past the first narrowed portion.

US Pat. No. 10,213,302

VALVE PROSTHESIS AND METHOD FOR DELIVERY

MEDTRONIC, INC., Minneap...

1. A valve prosthesis comprising:a valve body; and
a unitary frame including
a first tubular portion connected to the valve body, and
a second tubular portion configured to contact and conform to a native valve annulus in situ,
the unitary frame having
a delivery configuration in which the first tubular portion is positioned in series with the second tubular portion along a longitudinal axis of the unitary frame and the first tubular portion is longitudinally adjacent to the second tubular portion, and
an expanded configuration in which the first tubular portion is positioned within an interior area of the second tubular portion, such that the second tubular portion surrounds the first tubular portion and both of the first tubular portion and the second tubular portion extend parallel to the longitudinal axis of the unitary frame.

US Pat. No. 10,213,301

SYSTEMS AND METHODS FOR HEART VALVE THERAPY

Caisson Interventional, L...

1. A deployment frame system for controlling relative movements of a system of multiple catheters wherein at least one catheter of the multiple catheters is configured to deliver a medical device, the deployment frame system comprising:a plurality of clamps, each of the clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters;
a first frame, wherein at least one of the clamps is releasably coupled with the first frame;
a second frame, wherein at least two of the clamps are releasably coupled with the second frame, wherein the second frame is translatable parallel to a longitudinal axis of the first frame; and
a frame clamp mechanism whereby the second frame is damnable to the first frame at a plurality of relative longitudinal orientations between the first frame and the second frame.

US Pat. No. 10,213,300

HYPOTUBE SHAFT WITH ARTICULATION MECHANISM

St. Jude Medical, Cardiol...

1. A device for delivering a medical aid into a patient, the device comprising:a hollow shaft having proximal and distal ends, a longitudinal axis, and flexible and rigid portions between the proximal and distal ends, the flexible portion being configured to bend away from the longitudinal axis and the hollow shaft distal end having an end face;
a guide bushing having a first lumen, an exterior surface, and a body defined between the first lumen and the exterior surface, a portion of the exterior surface of the guide bushing abutting the end face of the hollow shaft distal end;
a pull wire directly attached to and extending within the body of the guide bushing;
a flexible tube extending through the first lumen of the guide bushing; and
a sheath mechanically coupled to the flexible tube, the sheath surrounding a distal end of the flexible tube in a first position and being slidable to a second position to expose the distal end of the flexible tube,
wherein the guide bushing is in a first position when the pull wire is in a first position and the guide bushing is in a second position when the pull wire is in a second position.

US Pat. No. 10,213,299

VALVE DELIVERY SYSTEM WITH PINLESS RELEASE MECHANISM

BOSTON SCIENTIFIC SCIMED ...

1. A medical device, comprising:an inner shaft having a distal end region;
a valve implant releasably coupled to the distal end region;
wherein the valve implant is capable of shifting between an elongated configuration and an expanded configuration;
a deployment sheath capable of being disposed about the valve implant when the valve implant is in the elongated configuration;
a post assembly disposed along the valve implant;
wherein the post assembly includes a release member that is axially slidable within an opening in the post assembly, wherein a portion of the release member extends through the post assembly;
a rod designed to engage the release member, wherein the rod is designed to shift the valve implant between the elongated configuration and the expanded configuration; and
wherein shifting the portion of the release member extending through the post assembly from a first axial position within the post assembly to a second axial position within the post assembly releases the rod from the post assembly and deploys the valve implant;
wherein the rod has a forked distal end region.

US Pat. No. 10,213,298

PERCUTANEOUS HEART VALVE PROSTHESIS

Percutaneous Cardiovascul...

1. A percutaneous mitral valve prosthesis, comprising:a valve body having a valve body inlet end, a valve body outlet end and a passage extending along a longitudinal axis between said valve body inlet end and said valve body outlet end, said valve body being collapsible about said longitudinal axis for delivery via a catheter;
a plurality of flexible valve leaflets made from pericardial material, the valve leaflets secured to said valve body and extending across said passage such that valve leaflets collapse toward each other for blocking a blood flow in one direction through said passage from said valve body outlet end to said valve body inlet end;
a flexible skirt extending about a periphery of said valve body, said flexible skirt adapted for blocking the blood flow in said one direction between said valve body and the native wall of a mitral valve orifice; and
a plurality of prongs secured to said outlet end of said valve body and extending toward said inlet end of said body;
wherein said valve body tapers toward said valve body inlet end such that a diameter of the valve body inlet end is smaller than a diameter of the valve body outlet end;
wherein said valve body comprises a valve body frame comprising a plurality of valve body frame elements arranged to form a plurality of circumferentially extending rows of cells, wherein one row of cells comprises a plurality acute-angled vertices at said valve body inlet end and another row of cells comprises a plurality of acute-angled vertices at said valve body outlet end.

US Pat. No. 10,213,297

CONTROLLING TISSUE ENGINEERED HEART VALVE GEOMETRY BY USING PREDEFINED INSERTS DURING CULTURE

UNIVERSITAET ZUERICH, Zu...

1. A heart valve culturing device, wherein the heart valve comprises at least two leaflets, the device comprising:a. a support base; and
b. at least two inner arms each capable of supporting a tissue growth material to from one of the leaflets,
wherein each of the inner arms has a first portion and a second portion,
wherein the first portion is disposed normal to the support base and disposed proximal to a center of the support base,
wherein the second portion is nonlinear and disposed distal to the support base and blends away from the center of the support base,
wherein the at least two inner arms are spaced from each other defining enough space to fit at least the respective tissue growth materials;
the device further comprising a spacer to fit in said space and to separate the tissue growth materials supported by each of the linear portions of the inner arms;
the spacer comprises at least two planar surfaces, all of the planar surfaces having a common intersection line, the intersection line being substantially parallel to and circumferentially surrounded by said linear portions of the inner arms.

US Pat. No. 10,213,296

GRAFT INCLUDING OSSEOUS TISSUE AND CARTILAGE TISSUE FOR AUGMENTATION RHINOPLASTY, AND METHOD OF PERFORMING AUGMENTATION RHINOPLASTY USING THE GRAFT

1. A method of performing augmentation rhinoplasty, the method comprising:providing at least one first graft by isolating at least one part of a nasal septum from a nose of a subject, wherein the at least one first graft comprises both a first compartment consisting of osseous tissue and a second compartment consisting of cartilage tissue;
manufacturing a second graft for forming a line of nasal dorsum of the subject by excising a part of the at least one first graft, wherein the second graft comprises both a first compartment consisting of osseous tissue and a second compartment consisting of cartilage tissue;
preparing at least two pieces of the first graft by cutting another part of the at least one first graft, which remains after the manufacturing of the second graft, into at least two pieces, wherein the pieces of the first graft include pieces of bone, cartilage, or cartilage tissue;
forming two lines of nasal dorsum by inserting the second graft into a nasal dorsum of the subject; and
raising the nasal dorsum in a dorsal direction by inserting one or more of the at least two pieces of the first graft into a space between the two lines of nasal dorsum and positioned in a ventral direction with respect to the second graft that is inserted into the nasal dorsum of the subject.

US Pat. No. 10,213,295

INTRAOCULAR LENS INSERTION APPARATUS

Kowa Company, Ltd., Nago...

1. An intraocular lens insertion apparatus, comprising:a cylindrical body member configured to retain an intraocular lens;
a fore-end opening comprising a fore-end area provided for a tip of the body member; and
a planate protrusion provided for a tip of the fore-end opening,
wherein an end surface of the fore-end area of the fore-end opening is an oblique surface which is oblique to a plane perpendicular to a central axis of the body member,
wherein the fore-end area comprises a pair of lateral walls which are parallel to each other across the central axis, wherein the pair of lateral walls is formed on a side of the fore-end area, and
wherein the planate protrusion is configured to extend from the fore-end area to a distal end of the intraocular lens insertion apparatus, wherein the planate protrusion does not comprise a lateral wall or a bottom surface, such that the planate protrusion is open on both lateral sides and a bottom side thereof,
wherein the fore-end opening further comprises a back-end area connected to the fore-end area, and the back-end area comprises a pair of lateral walls,
wherein the lateral walls of the fore-end area increases in height from the distal end thereof to the proximal end thereof at a first slope,
wherein the lateral walls of the back-end area increases in height from the distal end thereof to the proximal end thereof at a second slope, and
wherein the first slope is greater than the second slope.

US Pat. No. 10,213,294

APPARATUS FOR USE IN A SURGICAL PROCEDURE

KELLER MEDICAL, INC., St...

1. An apparatus for use in a surgical procedure, the apparatus comprising:a flexible sleeve comprising: a first end region and a second end region, the flexible sleeve being tapered such that a width of the second end region is relatively smaller than a width of the first end region; an interior surface that forms an interior cavity, the interior cavity being sized to receive a filled breast implant; and a dry lubricant on the interior surface, the dry lubricant being activatable by moisture,
wherein the flexible sleeve comprises indicia for cutting the flexible sleeve, the indicia indicating dimensions for accommodating different implant sizes, and
wherein the flexible sleeve is manipulatable such that, when the filled breast implant is positioned within the interior cavity, a manually applicable directional pressure causes the filled breast implant to extrude from the second end region.

US Pat. No. 10,213,293

LIGHTWEIGHT BREAST IMPLANT MATERIAL

1. A prosthetic implant, comprising a polymeric gel and a plurality of additives, wherein said additives have been surface treated prior to incorporation with said polymeric gel with a surface treatment comprising at least one of organofunctional silanes, organofunctional titanates, organofunctional zirconates or long chain fatty acids;wherein said additives comprise a plurality of micro-lumens, and wherein said micro-lumens are rigid and comprise ceramic or glass;
wherein said additives that have been surface treated prior to incorporation with said polymeric gel and said gel undergo a curing reaction to cross-link said surface treated additives to said gel; and wherein the composite material is suitable for implantation to the human body;
wherein if the implant is ruptured the gel will continue to cover the micro-lumens, such that the body would only be exposed to said gel.

US Pat. No. 10,213,292

HYBRID ANCHOR

1. A hybrid anchor comprising:a core body made of a material selected from the group consisting of biocomposite, bioabsorbable, osteoconductive, and biocompatible non-absorbable, the core body comprising:
a proximal end, a distal end, and a longitudinal axis extending therethrough;
an aperture formed near the distal end of the core body and transverse to the longitudinal axis of the core body, the aperture configured to receive a suture;
a force receiving member disposed at the proximal end of the core body, the force receiving member configured to engage an inserter and to receive an insertion force applied by the inserter to the core body;
a tip disposed at the distal end of the core body;
a stop disposed at the proximal end of the core body; and
an elongated member extending between the stop and the tip along the longitudinal axis of the core body; and
a wing assembly made of a polymer, the polymer being different and more flexible than the material of the core body, the wing assembly comprising:
a sleeve comprising a proximal end, a distal end, and a surface extending therebetween, the sleeve fitted around the elongated member of the core body such that a distal-most end of the sleeve engages the tip and a proximal-most end of the sleeve engages the stop, the distal end of the sleeve being proximal to the aperture and the stop resisting proximal movement of the wing assembly along the elongated member; and
a plurality of wings formed on diametrically opposing sides of the sleeve and extending outwardly from the surface of the sleeve at an angle towards the proximal end of the sleeve.

US Pat. No. 10,213,291

VASCULAR REPAIR DEVICES

Bolto Medical, Inc., Sun...

1. A stent graft, comprising:a) a graft sleeve having a proximal end, a distal end, a sleeve diameter and a major longitudinal axis;
b) a bare stent having struts defining distal apices and proximal apices, the struts connecting the distal and the proximal apices and having a bare stent amplitude defined as a distance extending along a longitudinal length of the stent graft, the bare stent having a relaxed diameter that is greater than the sleeve diameter, the distal apices of the bare stent being secured at the proximal end of the graft sleeve, and the proximal apices of the bare stent extending beyond the proximal end of the graft sleeve; and
c) at least one stent at the proximal end of the graft sleeve distal to the bare stent, the at least one stent including struts defining distal apices and proximal apices, the proximal apices being nested between adjacent distal apices of the bare stent, the at least one stent having an amplitude defined as a distance extending along the longitudinal length of the stent graft and the at least one stent having a relaxed diameter greater than that of the sleeve diameter and being secured along its entirety to the graft sleeve, wherein the amplitude of the at least one stent is less than that of the bare stent amplitude, whereby an outward radial force of the at least one stent against the graft sleeve at any given diameter of the stent graft is greater than that of the bare stent.

US Pat. No. 10,213,290

BRAIDED STENT AND METHOD OF MANUFACTURING A BRAIDED STENT

BOSTON SCIENTIFIC SCIMED,...

1. A method of manufacturing a stent, comprising:interweaving one or more filaments around a stent mandrel, the one or more filaments each including a cross-sectional profile having at least one flattened portion, wherein the one or more filaments each include a generally round cross-sectional profile modified to form the at least one flattened portion; and
positioning a flattened portion of a first filament portion of the one or more filaments facing a flattened portion of a second filament portion of the one or more filaments.

US Pat. No. 10,213,289

BRONCHOSCOPIC LUNG VOLUME REDUCTION VALVE

Boston Scientific Scimed,...

1. A one way valve for a biological flow passage, comprising:a braided structure extending longitudinally from a proximal end to a distal end, the braided structure movable from a constrained configuration to an expanded configuration so that, upon insertion of the braided structure in the biological flow passage, the braided structure is maintained in the expanded configuration, the braided structure including a constricted portion at the distal end thereof, the constricted portion closing off a channel of the braided structure to define a funnel shape which prevents flow towards the distal end;
a non porous coating extending over a portion of the braided structure to prevent passage of fluids through the braided structure; and
an anchoring portion extending distally from the distal end of the braided structure to anchor the braided structure within the biological flow passage.

US Pat. No. 10,213,288

DISTAL PROTECTION FILTER

CRUX BIOMEDICAL, INC., M...

1. A system for providing embolic protection, the system comprising:a first sheath having a longitudinal axis, a proximal end, a distal end and a lumen, the lumen configured to receive a guidewire;
a first distal protection filter attached to a distal portion of the first sheath, the first distal protection filter comprising a self-expanding frame with a slidable crossover point that defines a proximal loop and a distal loop, and a filter element attached to one of the proximal loop or distal loop of the self-expanding frame of the first distal protection filter, wherein the filter element extends to the crossover point;
a second sheath disposed about the longitudinal axis and having a proximal end, a distal end and a lumen, the second sheath disposed over the first sheath, wherein the distal end of the second sheath is located proximally the first distal protection filter;
a second distal protection filter attached to a distal portion of the second sheath, the second distal protection filter comprising a self-expanding frame with a slidable crossover point that defines a proximal loop and a distal loop, and a filter element attached to the proximal loop of the self-expanding frame of the second distal protection filter, wherein the crossover point is proximal to the filter element, wherein the proximal loops and the distal loops each includes a proximal end and a distal end; and
an outer sheath disposed over both the first sheath and the second sheath; and
wherein when deployed, the proximal loops, the distal loops, and the slidable crossover points of the first distal protection filter and the second distal protection filter are substantially positioned on a same side of a plane within which the longitudinal axis of the first sheath extends,
wherein when deployed, the proximal ends of the proximal loops and the distal ends of the distal loops are substantially near the longitudinal axis, the distal ends of the proximal loops and the proximal ends of the distal loops at the crossover points are substantially away from the longitudinal axis.

US Pat. No. 10,213,287

IMPLANTABLE SELF-CLEANING BLOOD FILTERS

VeoSource SA, Lausanne (...

1. A method for implanting a blood filter that includes a filter portion and an anchor portion, said filter portion including an elbow portion and an extension portion, said elbow portion depending from said anchor portion, said extension portion having a proximal end that defines a bypass aperture, said extension portion including a superior face that defines a first porosity and an inferior face opposite said superior face that defines a second porosity, said first porosity being greater than said second porosity, the method comprising:disposing said anchor portion in a first artery of an aortic arch;
orienting said filter portion so that said bypass aperture is in a downstream direction of a blood flow in said aortic arch; and
positioning said blood filter so that said superior face of said extension portion of said filter portion is in contact with a wall of said aortic arch.

US Pat. No. 10,213,286

IMPLANTABLE MEDICAL DEVICE AND METHODS OF DELIVERING THE IMPLANTABLE MEDICAL DEVICE

Boston Scientific Scimed,...

17. A medical device configured to be delivered and placed within a patient's body, the medical device comprising:a first elongate member having a proximal end portion and a distal end portion defining a longitudinal axis, the first elongate member being made of a synthetic material;
a second elongate member made of a biologic material, the second elongate member having a first portion and a second portion, the first portion of the second elongate member being attached to the first elongate member along its entire length of the first portion of the second elongate member, the length being in a direction along the longitudinal axis of the first elongate member, the second portion of the second elongate member being attached to the first portion of the second elongate member at a transverse edge of the first portion of the second elongate member, the second portion of the second elongate member configured to move with respect to the first portion of the second elongate member, wherein the second elongate member is configured to form a defined non-planar shape, and
a third elongate member made of a biologic material, the third elongate member being attached to the distal end portion of the first elongate member in a planar manner, wherein the third elongate member is configured to be non-movable with respect to the first elongate member.

US Pat. No. 10,213,285

INFLATABLE HERNIA PATCH

1. A medical implant for strengthening an intra-abdominal defect, the medical implant comprising:a mesh layer;
a fluid chamber to contain pressure therethroughout;
the fluid chamber forming at least one of a ring and a rib; and
the fluid chamber connected to the mesh layer wherein inflation of the fluid chamber deploys the medical implant by extending the mesh layer toward a planar configuration.

US Pat. No. 10,213,284

CORNER-LOCK STITCH PATTERNS

TELA Bio, Inc., Malvern,...

1. A method for sewing a corner-lock stitch pattern, comprising (a) sewing or embroidering a first upper thread or yarn and a first lower thread or yarn in a first pattern into a substrate material, the first pattern comprising one or more curves, one or more angles, or a combination of one or more curves and one or more angles, and (b) sewing or embroidering a second upper thread and a second lower thread in a second pattern into the substrate material, the second pattern comprising one or more curves, one or more angles, or a combination of one or more curves and one or more angles; wherein at least one of the one or more curves or the one or more angles of the second pattern overlaps at least one of the one or more curves or the one or more angles of the first pattern, and one or more of the overlaps comprises a corner-lock stitch pattern comprising one or more thread interlace points and two or more thread overlays in which the second upper thread and second lower thread envelope the first upper thread and first lower thread.

US Pat. No. 10,213,283

TEXTILE-BASED PROSTHESIS FOR LAPAROSCOPIC SURGERY

Sofradim Production, Tre...

1. A prosthesis intended to be conveyed to an implantation site with the aid of a trocar, comprising:at least one flexible biocompatible textile having two opposite faces and a shape defining a longitudinal axis, and
at least one reinforcing element for said textile, the reinforcing element comprising at least one semi-rigid elongate rod segment situated in a distal region of the textile, one or more oblique rod segments situated in a proximal region of the textile and a triangular frame arranged between the elongate rod segment and the oblique rod segment, the at least one semi-rigid elongate rod segment fixed to at least one face of the two opposite faces of the textile and extending substantially parallel to the longitudinal axis along the at least one face, the rod segment having a proximal end and a distal end, the distal end provided with at least one fastening element having a shape of a ring and distinct from the textile, the fastening element configured to cooperate with a part of a tool that is able to pass through the trocar, in order to temporarily couple the prosthesis to the tool, wherein the one or more oblique rod segments are situated proximally to the proximal end of the at least one rod segment.

US Pat. No. 10,213,282

IN VITRO PLATFORM AND METHODS FOR CULTURING EMBRYOS FOR IMPLANTATION

California Institute of T...

1. A method of identifying in vitro implantation of an isolated mammalian embryo derived from a donor uterus, the method comprising:adding the isolated mammalian embryo derived from the donor uterus at Carnegie Stage 2, 3, or 4 or an equivalent mammalian stage to a first suspension comprising collagen or fibrinogen to form a second suspension comprising the isolated mammalian embryo and the collagen or the fibrinogen;
polymerizing the second suspension to form a polymerized matrix comprising collagen fibers or fibrin fibers with the isolated mammalian embryo embedded therein; and
observing or detecting remodeling or aggregation of the collagen fibers or the fibrin fibers in the polymerized matrix as an indication of in vitro implantation of the isolated mammalian embryo.

US Pat. No. 10,213,281

NON-SURGICAL SYSTEMS AND METHODS FOR TREATING RECEDING GUMS

1. A system for non-surgical treatment of receding gums, comprising:a dental impression selected from the group consisting of a) an impression of upper teeth and surrounding gums and b) an impression of lower teeth and surrounding gums, wherein the dental impression comprises:
a tooth impression portion conforming to portions of teeth having receded gums;
a gum impression portion conforming to portions of remaining gums surrounding the teeth having receded gums; and
a void portion configured to define a void extending along the teeth having receded gums and defining an area into which growth of the remaining gums is desired;
wherein the dental impression further comprises a vacuum channel extending along an inner surface off the dental impression to facilitate delivery of a vacuum force from a vacuum source to the void portion of the dental impression.

US Pat. No. 10,213,280

AUTOMATED METHOD OF MANUFACTURING ORAL APPLIANCES

ProSomnus Sleep Technolog...

1. A method of manufacturing an oral appliance, the method comprising the steps of:a) preparing a three-dimensional electronic model of a patient's dentition;
b) subtracting the three-dimensional electronic model of the patient's dentition from an image of a solid block to obtain an appliance data set;
c) determining a contour curve for the dentition, wherein the contour curve is placed at an offset distance at either the buccal or lingual side of the dentition, wherein the offset distance is a fraction of a visible buccal or lingual height of one of the posterior-most molars; and
d) manufacturing a dental appliance in accordance with the appliance data set and the contour curve.

US Pat. No. 10,213,279

DENTURE FIXING ATTACHMENT

1. A denture-fixing attachment for freely connecting a denture to a fixture implanted into an alveolar bone in a slanted direction by adjusting a denture angle of the denture with respect to the fixture, the denture-fixing attachment comprising:a rod-shaped joint member having an upper end for supporting the denture fixed thereto and a locking protruding portion protruding laterally from a lower portion of the joint member; and
an abutment having a coupling portion formed in an outer surface of a lower portion thereof so as to be coupled to a fixture recess formed in the fixture, and a receiving portion formed in an upper portion thereof so as to receive the lower portion of the joint member therein,
wherein the receiving portion of the abutment includes a receiving recess for receiving the lower portion of the joint member inserted thereinto, and a stop protruding portion provided in the receiving portion above the receiving recess and having a guide groove disposed adjacent to the stop protruding portion for guiding coupling movement of the locking protruding portion fitted thereinto,
wherein the guide groove includes a first guide groove part formed in a vertical direction, a second guide groove part formed at an end of the first guide groove part in a horizontal direction, and a third guide groove part formed at an end of the second guide groove part in the vertical direction, and wherein a bottom end of the vertical third guide groove part is open downward along the vertical direction at a distal end thereof, such that the locking protruding portion moves through and out of the guide groove and into the receiving recess as the joint member is inserted thereinto.

US Pat. No. 10,213,278

METHOD AND TOOLS FOR INDIRECT BRACKET POSITIONING

1. A positive tooth model, comprising: a model tooth; a model gum attached to the model tooth; a partial mock bracket attached to the model tooth; and a place holder, whereinthe partial mock bracket comprises a fully formed distal tie wing and no proximal tie wing;
the place holder replaces the proximal tie wing of the partial mock bracket and extends in a form of a rod or protrusion in a perpendicular direction starting from a horizontal median of the partial mock bracket to the gum of the tooth model.

US Pat. No. 10,213,277

DENTAL APPLIANCE BINDING STRUCTURE

Align Technology, Inc., ...

1. A removable dental appliance system, comprising:a first shell including:
a number of tooth apertures configured to receive a number of teeth of a patient's first jaw, at least one tooth aperture of the number of tooth apertures having an interior surface configured to apply an orthodontic repositioning force to reposition one or more teeth of the number of teeth; and
a first binding structure integrally formed with the first shell, the first binding structure including:
a first binding surface on the outer occlusal surface of the appliance, the first binding surface configured to mate with a first portion of an attachment surface of a first mandibular advancement feature; and
a second binding surface on the outer buccal surface of the appliance, the second binding surface configured to mate with a second portion of the attachment surface of the first mandibular advancement feature, wherein the first mandibular advancement feature is adhesively coupled to the first binding surface and the second binding surface with a flexible adhesive that substantially allows movement of the first mandibular advancement feature relative to the first binding surface and the second binding surface.

US Pat. No. 10,213,276

INSERT FOR ULTRASONIC BURR-DRILL UNIT

SOCIETE POUR LA CONCEPTIO...

1. An ultrasonic dental scaler appliance, comprising: at least one surgical handpiece connected to an ultrasound generator and at least one interchangeable ultrasound tip selectively mounted on the surgical handpiece, the tip consisting of:a first, treatment end having a distal end;
a second, base end having a bottom end configured to be selectively mounted on the surgical handpiece; and
at least one cavity forming a housing provided in the base end at a predetermined distance from the bottom end, such that the at least one cavity is located nearer the bottom end of the tip than the distal end, so as to project beyond the handpiece when the tip is mounted thereon so as to remain visible when the tip is mounted on the handpiece and during use thereof;
wherein the tip is monolithically formed, and an identifier element is received within the housing, the identifier element made of an elastic material that has a melting temperature higher than 130° C.

US Pat. No. 10,213,275

CUSTOM LINKABLE IMAGING AND MULTIFUNCTIONAL TRAY

IBUR, LLC, Troy, MI (US)...

1. A dental tray comprising:a clasping portion defining a receiving cavity configured to receive at least one oral structure having two opposing outer lateral surfaces and an upper surface disposed therebetween, the clasping portion comprising:
opposing lateral bands unitary with the clasping portion;
a top portion defined therebetween;
at least one rest unitary with the clasping portion and permanently extending away from the top portion into the receiving cavity, the rest shaped and configured to assist in stabilizing the tray;
a lateral contact unitary with the clasping portion and extending away from each of the lateral bands into the receiving cavity;
the receiving cavity defining an open space between both the upper surface and the outer surfaces of the received at least one oral structure;
wherein the top portion is configured to be spaced away from the upper surface of the oral structure with the at least one rest configured to selectively engage the upper surface to facilitate a tight and secure engagement between the clasping portion and the received at least one oral structure;
wherein the lateral contacts selectively engage at least one of the outer surfaces of the received at least one oral structure to facilitate a tight and secure engagement between the clasping portion and the received at least one oral structure; and
wherein the orientation of the at least one rest and the lateral contacts ensures that a majority of the received oral structure positioned within the receiving cavity of the dental tray is free from engagement with any element of the dental tray.

US Pat. No. 10,213,274

METHOD OF TRACKING AND NAVIGATION FOR A DENTAL INSTRUMENT

King Saud University, Ri...

1. A method of tracking and navigation for a dental instrument to assist a dental practitioner during a procedure on a patient with the aid of a computer system, comprising the steps of:establishing a fixed set of spatiotemporal marker tensors for the patient, Tj, where j=1, . . . , M;
producing a tomographic image of an area of interest of the patient, wherein the tomographic image is configured to be displayed to the dental practitioner;
providing the computer system, wherein the computer system includes at least a memory and a processor;
positioning a plurality of patient tracking markers on the patient in the area of interest, wherein the step of positioning the plurality of patient tracking markers on the patient in the area of interest comprises positioning a plurality of active and passive patient tracking markers on the patient in the area of interest;
positioning a plurality of instrument tracking markers on a dental instrument, wherein the step of positioning the plurality of instrument tracking markers on the dental instrument comprises positioning a plurality of active and passive instrument tracking markers on the dental instrument and defining visual sensors, M being a combined number of the positioned patient and instrument tracking markers;
providing the computer system, wherein the computer system includes at least a memory and a processor configured to perform the steps of:
a) establishing a set of spatiotemporal sensor tensors, Ih, where h=1, . . . , K, K being a number of visual sensors deployed for detecting the patient and instrument tracking markers, wherein the deployed visual sensors define a sensor array;
b) performing singular value decomposition on each of the spatiotemporal marker tensors to produce a corresponding pair of orthogonal tensors, and , and a corresponding singular values diagonal tensor, , where (a, b, c) represents a point in the diagonal tensor corresponding to a set of three-dimensional indices, (a, b, c);
c) calculating an lth feature space basis, BF(l), as BF(l)=[(a+r1u, b+r2u, c+r3u)|(a+r1v, b+r2v, c+r3v)], where l=1, . . . , L, and where L represents a total number of feature space bases, r1u, r2u, r3u, r1v, r2v, r3v are each predetermined ranges of values, and (a, b, c) is greater than a first threshold value, Threshold1;
d) calculating an lth extracted feature tensor, Fh(l), as Fh(l)=Ih*BF(l), wherein l=1, . . . , L and h=1, . . . , K;
e) calculating an lth saliency map, SMh(l) for each extracted feature tensor, Fh(l) as SMh(l)=FFT2{|FFT2{FFT2{Fh(l)(t)}}|}, where l=1, . . . , L and h=1, . . . ,K, and FFT2 represents a two-dimensional fast Fourier transform;
f) calculating an lth uncertainty map, UMh(l) for each saliency map, SMh(l) as UMh(l)=UMh(l)=SMh(l)?P[SMh(l)(a, b, c)>Threshold2|{I1,I2, . . . ,IK},{T1,T2, . . . , TM}], where P[.] represents a probability of a pixel (a, b, c) of the saliency map SMh(l) being above a second threshold value, Threshold2;
g) calculating a fused saliency map, FSM, as

h) calculating a binary fused map, FSMb, as FSMb=FSM when FSM is greater than a third threshold value, Threshold3; and
i) constantly providing the computer system with the results of each of the calculations and repetitively recalculating the location of the dental instrument;
overlaying the binary fused map on the tomographic image to provide visual feedback of the dental instrument relative to the area of interest of the patient on a display; and
repetitively returning to the step of performing singular value decomposition on each of the spatiotemporal marker tensors, wherein distance between the spatiotemporal marker tensors can then be computed by recalculating the point in the diagonal tensor S corresponding to a set of three-dimensional indices, (a, b, c).

US Pat. No. 10,213,273

DRILL LIMIT SYSTEM AND METHOD OF USING SAME

Implant Direct Sybron Int...

1. A drill limit system for providing a drill stop with a drill bit, comprising:a holder including at least one drill stop positioned on the holder and configured to receive at least one drill bit therethrough, wherein the at least one drill stop has a first state in which the at least one drill bit is configured to be movable relative to the at least one drill stop and a second state in which the at least one drill stop is configured to be secured to the at least one drill bit; and
a platform operatively coupled to the holder and having a surface configured to engage a tip end of the at least one drill bit,
wherein the holder and the platform are movable relative to each other such that the position of the at least one drill stop relative to the at least one drill bit may be selectively varied in order to locate the at least one drill stop at a desired position on the at least one drill bit, wherein the platform is configured to be vertically stationary and the holder is configured to be movable relative to the platform, and wherein rotation of the holder causes vertical movement of the holder relative to the platform.

US Pat. No. 10,213,271

ILLUMINATING SURGICAL DEVICE AND CONTROL ELEMENT

Illumix Surgical Canada I...

1. An illuminating surgical device, comprising:a two-dimensional array of illuminating elements to direct light toward a surgical field; and
a single control element to control an intensity of light from the two-dimensional array of illuminating elements and to control placement of the illuminated surgical field, wherein movement of the single control element along a first axis is to control a direction of light from the two-dimensional array of illuminating elements parallel to the first axis, and wherein movement of the single control element along the first axis is to control a plurality of louvers, the plurality of louvers to control the direction of the light from the two-dimensional array of illuminating elements.

US Pat. No. 10,213,270

SMALL DISPOSABLE TORQUE LIMITING DRIVING TOOL WITH RUBBER GRIP

Lomack Industrial Co. Ltd...

1. A self-limiting torque applying tool, comprising:a hollow housing including a grip surface, a longitudinal central axis, a proximal end, a distal end, and a cap rotatably engageable with the proximal end;
a working shaft drivingly coupled to the hollow housing and rotatable relative to the hollow housing about the longitudinal central axis;
a torque limiting clutch operably between the working shaft and the hollow housing, the torque limiting clutch configured to enable transmission of torque from the hollow housing to the working shaft while limiting maximum transmitted torque to a predetermined value;
a torque adjuster operable to adjust the maximum transmitted torque to the predetermined value; and
an adjusted torque sensing feature contained within the hollow housing.

US Pat. No. 10,213,267

SURGICAL DRAPE WITH CONTROL MECHANISM

Tenet Medical Engineering...

12. A method of activating a surgical instrument from a point within a sterile field during a surgical procedure, wherein the surgical instrument is located outside of the sterile field, comprising the steps of:a) providing a surgical drape including a tubular main body having an open proximal end, a distal end, and a longitudinal axis extending between the proximal and distal ends, the main body configured for passage of a surgical instrument through the open proximal end along the longitudinal axis of the main body, a dam portion attached to the distal end of the main body, the dam portion comprising a material selected to be different than a material of the main body, and a control mechanism attached to an outer surface of the main body between the proximal and distal ends, the control mechanism comprising an electrical switch completing an electrical connection on the sterile side for activating the surgical instrument and including a communication interface for interfacing with the surgical instrument;
b) covering the surgical instrument with the surgical drape to define the sterile field externally to the surgical drape;
c) enabling the communication interface so that the communication interface is capable of sending electrical control signals across a sterile barrier defined by the surgical drape to the surgical instrument; and
d) activating, on a sterile side of the surgical drape within the sterile field, the control mechanism to activate the surgical instrument, the activation performing an electrical activation responsive to a mechanical activation of the control mechanism, the mechanical activation and the electrical activation occurring on the sterile side of the barrier,
wherein the electrical switch is attached to a backing sheet that is releasably attached to a release sheet on the outer surface of the main body and wherein the backing sheet may be removed from the release sheet and releasably attached to another surface in the sterile field; and
wherein an opening formed at a distal terminus of the dam portion along the longitudinal axis is configured to permit passage therethrough of an operative arm of the surgical instrument for engaging a patient's limb or other surgical instrument.

US Pat. No. 10,213,266

ROBOTIC SURGICAL ASSEMBLIES AND ADAPTER ASSEMBLIES THEREOF

Covidien LP, Mansfield, ...

1. A torque transducer for mounting a motor, comprising:a mounting flange configured to secure the torque transducer to a fixed structure;
a motor flange configured to secure to a motor;
a body interconnecting the mounting and motor flanges, the body defining a channel about a longitudinal axis of the body, the body configured to flex in response to the mounting flange and the motor flange rotating relative to one another in response to torque of the motor; and
a strain gauge positioned on the body to measure flexation of the body.

US Pat. No. 10,213,265

MANIPULATOR AND MANIPULATOR SYSTEM

OLYMPUS CORPORATION, Tok...

1. A manipulator comprising:a main unit provided on a proximal end of the manipulator;
an elongated portion configured to extend from the main unit;
a distal end of the elongated portion, the distal end configured to bend or flex with respect to the elongated portion;
a wire coupled to the main unit and the distal end;
wherein the main unit comprises:
a drive unit configured to generate driving power to bend or flex the distal end,
a rotary unit comprising:
a shaft member configured to be rotated by the driving power,
a disc member mounted on an outer periphery of the shaft member, and
a peripheral wall mounted on the disc member along the circumference of the disc member,
an elastic unit located along an outer peripheral surface of the peripheral wall,
a first lock portion configured to lock one end of the elastic unit to the rotary unit, and wherein the wire connects the elastic portion and is wound along the peripheral wall, and the wire is configured to transmit the driving power.

US Pat. No. 10,213,263

FLEXIBLE-MANIPULATOR GUIDE MEMBER AND FLEXIBLE MANIPULATOR

OLYMPUS CORPORATION, Tok...

1. A manipulator comprising:a guide extending along a longitudinal axis, wherein the guide comprises:
a lumen inner surface configured to define a lumen extending along the longitudinal axis of the guide,
wherein the lumen comprises a first portion and a second portion along the longitudinal axis, and
wherein at least the first portion of the lumen has a spiral-shape extending along the longitudinal axis; and
a wire arranged within the lumen defined by the lumen inner surface,
wherein the wire is configured to transmit a driving force generated by an actuator to a movable structure, and
wherein the lumen inner surface is configured such that:
a path length of the lumen per unit length of the guide along the longitudinal axis in the first portion of the lumen is different from a path length of the lumen per unit length of the guide along the longitudinal axis in the second portion of the lumen.

US Pat. No. 10,213,262

MANIPULATABLE SURGICAL SYSTEMS WITH SELECTIVELY ARTICULATABLE FASTENING DEVICE

Ethicon LLC, Guaynabo, P...

1. A surgical system, comprising:a first rotary output member;
a second rotary output member;
a third rotary output member;
a surgical end effector, comprising:
a first jaw and a second jaw, wherein one of said first and second jaws is movable relative to the other of said first and second jaws between open and closed positions upon application of jaw control motions thereto and wherein one of said first and second jaws comprises a surgical staple cartridge; and
a firing member axially movable between a starting position and an ending position within said first and second jaws, said firing member configured to axially pass through said first and second jaws to eject surgical staples housed within said surgical staple cartridge and wherein said surgical system further comprises:
an elongate shaft assembly defining a longitudinal tool axis and operably coupled to said surgical end effector to facilitate selective articulation of said surgical end effector relative to said longitudinal tool axis, said elongate shaft assembly comprising:
a plurality of articulation members movably supported by said elongate shaft assembly and operably interfacing with said surgical end effector; and
a firing shaft operably interfacing with said firing member to apply a firing motion thereto and wherein said surgical system further comprises:
an articulation transmission operably interfacing with said first rotary output member and said plurality of articulation members such that rotation of said first rotary output member applies articulation motions to said plurality of articulation members;
a firing drive member operably coupled to said firing shaft and being configured to interface with said second rotary output member to apply firing control motion to said firing shaft; and
a closure clutch assembly operably interfacing with said elongate shaft assembly and said third rotary output member to receive a third rotary output motion therefrom to thereby selectively axially advance at least a portion of said elongate shaft assembly along said longitudinal tool axis to apply said jaw control motions to at least one of said first and second jaws.

US Pat. No. 10,213,261

EXTERNAL FIXATOR DEFORMITY CORRECTION SYSTEMS AND METHODS

Stryker European Holdings...

1. A computer-implemented method comprising employing at least one processor to execute instructions to:generate a display of an ellipse superimposed on a display of at least one digital medical image, the at least one digital medical image displaying a representation of a patient's anatomical structure, the ellipse being a graphical representation of a ring of a synthetic external fixator representing a physical external fixator attachable to the patient's anatomical structure, the physical external fixator comprising at least two rings interconnected by a plurality of struts;
receive strut attachment point user input representing actual or planned points of attachment of the plurality of struts to the at least two rings of the physical external fixator, wherein a selected one of the plurality of struts is coupled or is planned to be coupled to a selected one of the at least two rings via an intermediary piece of hardware; and
generate a bone deformity correction plan specifying for each strut a sequence of strut lengths to be used in a bone deformity correction treatment.

US Pat. No. 10,213,260

END FIRE FIBER ARRANGEMENTS WITH IMPROVED EROSION RESISTANCE

1. An arrangement for delivering treatment radiation to tissues situated laterally of an optical fiber through which the treatment radiation is delivered, comprising:a protective ferrule surrounding and enclosing a treatment end of an optical fiber adjustably positioned within the protective ferrule; and
a cannula in which the optical fiber and protective ferrule are mounted, wherein:
treatment radiation is emitted axially from an end of the optical fiber through the protective ferrule,
the cannula has a pre-formed curvature,
the curvature of the cannula is assumed by the optical fiber mounted therein to cause treatment radiation emitted axially through an end of the fiber to be directed laterally at tissues situated to a side of the fiber, and
the cannula has sufficient flexibility to enable the cannula and fiber to straighten when withdrawn into a straight working channel of a scope, the cannula and fiber returning to the pre-formed curvature when extended out of the working channel.

US Pat. No. 10,213,259

MEDICAL LASER TREATMENT DEVICE AND METHOD FOR OPERATING SAME

LUTRONIC CORPORATION, Go...

1. A method of operating a medical laser treatment device, which includes a body having a laser generator and a handpiece connected to the body, the method comprising:(a) contacting skin of a patient with the handpiece;
(b) pressing a portion of a blood vessel by pressing a first area of the skin with the handpiece so as to expand a portion of the blood vessel, the pressed portion of the blood vessel being located under the first area of the skin, the expanded portion of the blood vessel being located upstream of the pressed portion of the blood vessel; and
(c) irridiating a laser into a second area of the skin under which the expanded portion of the blood vessel is located by operating the laser generator in the body,
wherein the medical laser treatment device further comprises a laser tip detachably coupled to the handpiece, the laser tip including a guide body that has a specific shape, the specific shape defining the second area of the skin into which the laser irradiates.

US Pat. No. 10,213,258

MEDICAL LASER SYSTEM

Lymol Medical, Inc., Wob...

1. A medical laser system, comprising:a crystal-based laser;
a pointer laser;
a power supply for powering the crystal-based laser and the pointer laser;
a controller operably connected to the crystal-based laser, the pointer laser, and the power supply; and
a memory operably connected to the controller;
wherein the controller is programmed to:
(a) selectively activate the crystal-based laser to cause a laser light emission by adjustably controlling power supplied by the power supply to the crystal-based laser responsive to a user activation input;
(b) selectively activate the pointer laser to cause a pointer laser light emission by adjustably controlling power supplied by the power supply to the pointer laser responsive to a user activation input; and
(c) record data in the memory in connection with treatment of a patient, said data indicating the total exposure of the patient to radiation emitted by the crystal-based laser and the pointer laser during activation thereof.

US Pat. No. 10,213,257

DEVICES AND METHODS FOR OPTICAL DETECTION OF TISSUE CONTACT

COVIDIEN LP, Mansfield, ...

1. A method of directing energy to tissue, comprising:positioning an energy applicator for delivery of energy to target tissue, the energy applicator operably associated with an electrosurgical power generating source and having a waveguide, the waveguide including electrically conductive walls that define a cavity therein and a plurality of dielectric layers disposed coaxially with a longitudinal axis defined by the cavity;
generating optical signals from the energy applicator;
determining a position of the energy applicator relative to the target tissue based on a reflection of the generated optical signals; and
transmitting energy to the target tissue via the waveguide based on the determination of the position of the energy applicator relative to the target tissue.

US Pat. No. 10,213,256

SYSTEM AND METHOD FOR MONITORING ABLATION SIZE

COVIDIEN LP, Mansfield, ...

1. A method for monitoring ablation size, the method comprising:transmitting microwave energy from a power source to a microwave antenna to form a tissue ablation zone;
measuring near field electromagnetic radiation emitted from the microwave antenna at a resonator coupled to the microwave antenna;
transmitting a detection signal corresponding to the measured near field electromagnetic radiation to the power source; and
adjusting at least one property of the microwave energy from the power source to the microwave antenna based on the detection signal.

US Pat. No. 10,213,255

ELECTROSURGICAL DEVICES HAVING DIELECTRIC LOADED COAXIAL APERTURE WITH DISTALLY POSITIONED RESONANT STRUCTURE AND METHOD OF MANUFACTURING SAME

COVIDIEN LP, Mansfield, ...

1. An electrosurgical device for delivering energy to tissue, comprising:an antenna assembly defining a longitudinal axis and including a dielectric sleeve, the dielectric sleeve including:
a first dielectric segment; and
a second dielectric segment configured to be coupled to the first dielectric segment about the longitudinal axis of the antenna assembly, the first and second dielectric segments cooperatively defining a longitudinal channel extending along the longitudinal axis; and
a feedline including a dielectric material surrounding an inner conductor, the inner conductor including a distal portion disposed distally beyond the dielectric material, the distal portion of the inner conductor disposed within the channel defined by the first and second dielectric segments.

US Pat. No. 10,213,254

CATHETER WITH LIQUID-COOLED CONTROL HANDLE

Biosense Webster, Inc., ...

1. An electrophysiologic catheter, comprising:a catheter body;
a control handle proximal the catheter body, the control handle housing a printed circuit board on which is mounted one or more integrated circuits; and
a heat transfer assembly including:
a pump,
a reservoir containing a coolant,
a cooling unit configured to cool the coolant,
a heat transfer member within the control handle and mounted on the printed circuit board, and
a coolant transport network providing coolant communication between at least the reservoir or cooling unit and the heat transfer member mounted on the printed circuit board.

US Pat. No. 10,213,253

ESTIMATING A TEMPERATURE DURING ABLATION

Biosense Webster (Israel)...

1. A method for use with an intra-body probe, a distal end of which includes an ablation electrode and a temperature sensor, the method comprising, using a processor:while (i) the ablation electrode is driving an ablating current into tissue of a subject, and (ii) fluid is passed from the distal end of the intra-body probe at a fluid-flow rate, receiving a temperature sensed by the temperature sensor;
estimating a temperature of the tissue, based at least on the sensed temperature and at least one parameter selected from the group consisting of: the fluid-flow rate, and a parameter of the ablating current, comprising selecting a coefficient in response to the at least one parameter, and estimating the temperature of the tissue, at least by multiplying, by the coefficient, a value that is based on the sensed temperature; and
generating an output in response to the estimated temperature.

US Pat. No. 10,213,252

INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE

Vessix, Inc., Laguna Hil...

1. A system for remodeling tissue disposed about a blood vessel, the system comprising:an endovascular catheter having an energy delivery portion adapted to be coupled with a target tissue, wherein the catheter includes a balloon, wherein the energy delivery portion comprises a plurality of electrodes disposed about the balloon of the catheter so as to define a plurality of remodeling zones in the target tissue when the balloon is in contact with a blood vessel wall disposed adjacent to the target tissue; and
an energy source coupleable with the catheter, the energy source being configured to deliver a controlled quantity of energy to each of the plurality of electrodes in response to an input such that the controlled quantity of energy heats at least some of the plurality of remodeling zones of the target tissue so as to remodel the target tissue and inhibit thermal damage of collateral healthy tissues;
wherein the plurality of remodeling zones includes a first remodeling zone and a second remodeling zone disposed adjacent to the first remodeling zone and wherein the plurality of electrodes comprise a plurality of bipolar electrode pairs spaced around an axis of the balloon so that the plurality of remodeling zones defined by the bipolar electrode pairs are laterally separated from each other so as to form gaps between the first remodeling zone and the second remodeling zone;
wherein the energy source includes a processor, wherein the processor is designed to determine a frequency or range of frequencies at which a first impedance of the target tissue is equal to or greater than a second impedance of the collateral healthy tissue; and wherein the processor is configured to deliver the controlled quantity of energy delivered to the plurality of electrodes at the frequency or range of frequencies.

US Pat. No. 10,213,250

DEPLOYMENT AND SAFETY MECHANISMS FOR SURGICAL INSTRUMENTS

COVIDIEN LP, Mansfield, ...

1. A surgical instrument, comprising:first and second members, at least one of the members movable relative to the other between a spaced-apart position and an approximated position;
a deployable component movable between a retracted position and an extended position; and
a trigger assembly, including:
a trigger portion engaged with the first member, the trigger portion including a trigger configured to move relative to the first member between an un-actuated position and an actuated position;
a linkage portion engaged with the second member and having the deployable component engaged thereto, the linkage portion movable between a first position and a second position for moving the deployable component between the retracted position and the extended position;
a pinion configured to rotate to convert movement of the trigger into movement of the linkage portion when the trigger portion and the linkage portion are engaged to one another, wherein the trigger portion further includes a first gear rack engaged to the trigger and disposed in meshed engagement with the pinion such that movement of the trigger effects rotation of the pinion,
wherein, in the spaced-apart position of the members, the trigger portion and the linkage portion are disengaged from one another such that movement of the trigger between the un-actuated position and the actuated position does not effect movement of the deployable component, and
wherein, upon movement of the first and second members to the approximated position, the trigger portion and the linkage portion are moved into engagement with one another such that movement of the trigger between the un-actuated position and the actuated position effects movement of the linkage portion between the first and second positions to thereby effect movement of the deployable component between the retracted and extended positions.

US Pat. No. 10,213,249

ELECTROSURGERY HANDPIECE/PENCIL WITH SMOKE EVACUATION

I.C. Medical, Inc., Phoe...

1. An electrosurgery pencil comprising:a hollow tubular handpiece member having a first end and a second end;
a planar platform located near a top of the hollow tubular handpiece member having a first opening traversing through the planar platform and into an interior of the hollow tubular handpiece member where the first opening is located near the first end of the hollow tubular handpiece member;
an electrode positioned within the first end of the hollow tubular handpiece member;
a circuit board seated on said planar platform;
at least one wire passing through the first opening in the planar platform for connecting the circuit board to the electrode;
an electrical cord containing one or more insulated wires for connecting said circuit board to an energy source; and
one or more depressable button members positioned above said circuit board for enabling selective contact with said circuit board.

US Pat. No. 10,213,248

ADAPTIVE ELECTRODE FOR BI-POLAR ABLATION

BIOSENSE WEBSTER (ISRAEL)...

1. An ablation apparatus, comprising: a first flexible probe adapted for insertion into a heart of a living subject and having a distal segment and a first ablation electrode disposed at the distal segment to be brought to a target tissue at a first side of a wall of the heart; a second flexible probe adapted for insertion into the living subject and having a distal end and a second ablation electrode disposed at the distal end, the second ablation electrode to be brought to an opposing second side of the wall to oppose the first ablation electrode, the second ablation electrode comprising a plurality of segments, the segments being concentric and electrically insulated from one another; and a power generator connectable to the first ablation electrode and switchably connectable to selected ones of the segments of the second ablation electrode for passing electric current from the first ablation electrode and through the target tissue and for passing electric current from the selected segments of the second ablation electrode and through the tissue, the first ablation electrode having a fixed current transmission area and the second ablation electrode having a variable current transmission area, the variable current transmission area being selected to form a transmural lesion between the first ablation electrode and the second ablation electrode.

US Pat. No. 10,213,247

THERMAL RESECTING LOOP

Domain Surgical, Inc., S...

1. A thermal resecting instrument, comprising:a thermal element comprising:
a conductor loop having a curved portion; and
a ferromagnetic coating covering at least the curved portion of the conductor loop, the ferromagnetic coating extending directly from a first end to a second end and forming a ferromagnetic region disposed along the conductor loop, the ferromagnetic region having a curvature between the first end and the second end that defines at least a part of an opening for receiving tissue, the conductor loop extending from a first position spaced apart from the first end of the ferromagnetic coating, through the ferromagnetic region and to a second position spaced apart from the second end of the ferromagnetic coating;
wherein, in use, the ferromagnetic coating is responsive to passage of electrical energy through the conductor loop to produce heat.

US Pat. No. 10,213,246

TISSUE ABLATION SYSTEMS AND METHOD

Hermes Innovations LLC, ...

1. A method of delivering electrosurgical energy to targeted tissue, said method comprising:providing a gas-filled chamber surrounded by a thin-walled dielectric barrier;
engaging an exterior of the gas-filled chamber against the targeted tissue;
coupling an RF current source between an electrode within the gas-filled chamber and the targeted tissue to initiate high-voltage, alternating current, gaseous discharges within the gas-filled chamber to deliver the current from the current source to the targeted tissue.

US Pat. No. 10,213,245

CONTINUOUS FLOW BALLOON CATHETER SYSTEMS AND METHODS OF USE

PAVmed Inc., New York, N...

1. A system for balloon inflation, the system comprising:a catheter having an inflow lumen and an outflow lumen;
a balloon positioned at a distal end of the catheter, the balloon being in fluid communication with the inflow and the outflow lumen; and
an infusion device having an inflow chamber in fluid communication with the balloon via the inflow lumen, and having an outflow chamber in fluid communication with the balloon via the outflow lumen, the infusion device configured for simultaneously circulating a fluid into and out of the balloon via the inflow lumen and the outflow lumen, respectively, at matching flow rates in order to keep the balloon volume and pressure constant during an entire infusion.

US Pat. No. 10,213,244

CRYOGENIC NEEDLE WITH FREEZE ZONE REGULATION

Myoscience, Inc., Fremon...

1. A system comprising:a controller;
a cooling supply system having a valve controlled by the controller; and
a needle probe coupled to the controller and configured to receive coolant from the coolant supply system, the needle probe having at least one needle and a heater thermally coupled to the at least one needle;
wherein the controller is configured to:
regulate the coolant to the needle probe using the valve;
provide power to the heater based on power demand from the heater;
monitor the power provided to the heater; and
perform a correlation of the monitored power with at least one of a tissue characteristic and/or an operating parameter;
wherein the heater is further configured to actuate the valve to provide more or less of the coolant to the needle probe based on at least one of the correlated tissue characteristic and/or the operating parameter.

US Pat. No. 10,213,242

FASTENING DEVICE AND TOOL FOR SURGICAL HOLDING SYSTEMS

CREAHOLIC S.A., Biel (CH...

1. A fastening device for surgical holding systems, comprising a holding element and a fastening element that are mechanically connectable to one another, and a clamping element,wherein the holding element comprises a joint socket, and the fastening element comprises a joint head, wherein the joint socket and the joint head are shaped in a manner corresponding to one another and form a ball joint, and movement of the ball joint is lockable by way of the clamping element,
wherein the clamping element is an eccentric ring that, on rotation, clamps the joint head with respect to the joint socket,
wherein the joint socket defines a joint inner surface of the ball joint, and the joint head defines a joint outer surface of the ball joint, the joint outer surface being part of a sphere,
wherein the ball joint is formed by contact between the joint inner surface and the joint outer surface,
wherein the eccentric ring is rotatably arranged on the holding element and on rotation of the eccentric ring with respect to the holding element, the eccentric ring is pressed against the joint outer surface of the ball joint to lock the movement of the ball joint.

US Pat. No. 10,213,241

METHOD AND DEVICE FOR INSERTION OF ORTHOPEDIC FIXATION PIN WITH BLIND HOLE

Wright Medical Technology...

1. A method, comprising:inserting a k-wire into a bone such that a portion of the k-wire extends from a surface of the bone;
sliding a blind hole of a fixation device over a portion of the k-wire that extends from a surface of the bone;
driving the fixation device into the bone along an axis defined by the k-wire, a bottom wall of the blind hole contacting an end of the k-wire as the fixation device is driven into the bone; and
removing the k-wire from the blind hole.

US Pat. No. 10,213,240

DEPLOYABLE ANCHOR FOR BONE FIXATION

CABLE FIX LLC, Hernando,...

1. A deployable anchor for bone fixation, comprising:a head, positionable within or entirely through an interior portion of a bone and, while positioned within or entirely through the interior portion of the bone, deployable to frictionally engage the bone and fixate the head relative to the bone;
a cable, coupled to the head, wherein the cable is configured to be tensioned to a measurable and adjustable tension; and
a washer fixedly coupled with the head.

US Pat. No. 10,213,239

POROUS PLATE FOR MEDICAL USE AND MANUFACTURING METHOD OF POROUS PLATE FOR MEDICAL USE

FUKUSHIMA MEDICAL UNIVERS...

1. A porous plate for medical use made of a thin-plate substrate comprising a pore perforation section having a plurality of pores perforated therein and a frame section surrounding the pore perforation section, whereinthe thin-plate substrate is a biocompatible metal material,
the pore perforation section has crosspieces which extend lengthwise and crosswise in continuity with the frame section and partition the pore perforation section into a plurality of parts, and a plurality of pore perforation cells each surrounded by the crosspieces, and
the pores perforated in the pore perforation cells have a pore diameter of 1 to 50 ?m, and a center-to-center distance between adjacent pores is 2 to 200 ?m.

US Pat. No. 10,213,238

METHOD AND DEVICE FOR CORRECTING BONE DEFORMITIES

FastForward Surgical Inc....

1. A method of correcting an angular bone deformity in a foot between an unstable bone of the foot and an adjacent stable bone of the foot, comprising:drilling a first opening and a second opening through the unstable bone;
passing a suture through the first opening and positioning the suture such that the suture extends between the adjacent stable bone and the unstable bone;
placing the suture, under tension to reduce the angular deformity between the unstable bone and the adjacent stable bone;
wherein the suture is secured to the unstable bone within the first opening and the second opening that are spaced apart; and
wherein the suture is secured within the first opening and the second opening with a pair of interference screws.

US Pat. No. 10,213,237

PERIPROSTHETIC EXTENSION PLATE

Stryker European Holdings...

25. A method of performing osteosynthesis of a bone part or fragment, comprising:receiving a first fastener into a first portion of an extension plate defining a longitudinal axis, wherein the first portion of the extension plate extends into a hole defined by an inner wall of an elongate plate to attach the extension plate to the elongate plate such that the first fastener does not contact the elongate plate and such that the first portion of the extension plate lies between the first fastener and the inner wall; and
receiving a second fastener into a second portion of the extension plate and into a bone part or fragment, the second portion of the extension plate defining a longitudinal axis, wherein the longitudinal axes defined by the first and second portions of the extension plate are nonparallel when the extension plate is detached from the elongate plate, and wherein the first portion of the extension plate is rotatable such that the second portion is movable relative to the elongate plate.

US Pat. No. 10,213,236

ORTHOPEDIC COMPRESSION PLATE AND METHOD OF SURGERY

Orthohelix Surgical Desig...

1. A system, comprising:a plate having a top surface opposing a bone facing surface in a z-direction and extending along a longitudinal axis from a first end to a second end, wherein the plate includes at least one slot extending from the top surface to the bone facing surface and having opposed faces and a slot mid-plane is defined such that it is positioned an equal distance from each of the opposed faces, and a top plane is defined tangent to the top surface and orthogonal to the slot mid-plane, wherein the plate includes a screw housing extending from the bone facing surface of the plate and a first screw hole extending from the top surface of the plate through the screw housing, wherein the first screw hole extends along a first axis that intersects both the slot mid-plane and the top plane at an oblique angle, wherein the top surface of the plate defines an opening in communication with the first screw hole, and wherein the second end of the plate is chamfered for insertion of the second end into a bone; and
a screw including a head configured to be at least partially received within the opening in the top surface of the plate, wherein the head has a complimentary profile with respect to the opening such that screw can be positioned at a variable angle relative to the longitudinal axis of the plate.

US Pat. No. 10,213,235

SPINOUS PROCESS FUSION DEVICES AND METHODS THEREOF

Globus Medical, Inc., Au...

1. An implantable device comprising:a rod, the rod having a first portion and second portion and having ratchet receivers;
a first wing coupled to the rod on the first portion;
a second wing having an opening and having ratcheting members and being engageable to the rod through the opening;
a central barrel having a first side and a second side, the central barrel capable of being received at least partly around the rod,
wherein the central barrel is configured to distract adjacent spinous processes,
wherein a locking mechanism secures the second wing to the rod, and
wherein the central barrel is configured to be positioned in an interspinous space,
wherein the ratchet receivers of the rod when in a first position engage the one or more ratcheting members and when in a second position the ratchet receivers disengage from the one or more ratcheting members, and
wherein the rod is rotated to move from the first position to the second position.

US Pat. No. 10,213,234

INTERSPINOUS PROCESS FIXATION DEVICES, SYSTEMS, INSTRUMENTS AND METHODS OF ASSEMBLY AND USE

IN QUEUE INNOVATIONS, LLC...

1. A spinous process fixation device, comprising:a first attachment portion comprising:
a first member; and
a second member configured to couple to the first member;
a second attachment portion engaging the first attachment portion, the second attachment portion comprising:
a third member; and
a fourth member configured to couple to the third member;
wherein the first attachment portion and the second attachment portion are positioned to couple to at least two spinous processes;
wherein the first member comprises:
a body;
an engagement member;
a plurality of teeth positioned on the engagement member; and
a slot positioned on an exterior surface of the body and extending from a first side to a second side of the body,
wherein the second member includes comprises:
a body; and
an engagement portion, and the engagement member of the first member couples to the engagement portion of the second member; and
wherein the third member comprises:
a body;
an engagement member; and
a protrusion extending away from an interior surface of the body and extending from a first side to a second side,
wherein the protrusion of the third member engages the slot of the first member when the first attachment portion couples to the second attachment portion,
wherein the fourth member comprises:
a body; and
an engagement portion, and
wherein the engagement member of the third member couples to the engagement portion of the fourth member.

US Pat. No. 10,213,233

DYNAMIC AND NON-DYNAMIC INTERSPINOUS FUSION IMPLANT AND BONE GROWTH STIMULATION SYSTEM

AURORA SPINE, INC., Carl...

1. An interspinous fusion device comprising:a first member having a ring with two or more anchor assemblies projecting laterally from substantially opposite sides of said first member ring, the first member further comprising two columns of teeth formed integrally with the first member;
a second member having a ring with two or more anchor assemblies projecting laterally from substantially opposite sides of said second member ring, the second member further comprising one or more hollow barrels and at least two columns of recesses, said two columns of recesses adapted to mate with the two columns of teeth of the first member, said one or more barrels having opposing window passageways in between the two columns of recesses, such that when the first member is mated with the second member there are no other mechanical components within the one or more barrels such that an unobstructed passage is formed through the window passageways through which bone graft material can extend, and wherein the first member and the second member lock together when the teeth and recesses are mated, said locking occurring without the aid of a set screw, pin or other mechanical component.

US Pat. No. 10,213,232

SYSTEMS, ASSEMBLIES AND METHODS FOR SPINAL DEROTATION

SpineCraft, LLC, Westmon...

13. An assembly useful in a system for correcting alignment of one or more vertebrae of a spine, said assembly comprising:a derotator member comprising:
a first elongate element having a first proximal end portion and a first distal end portion, said first distal end portion being longitudinally split into at least two split portions configured to releasably engage with an implant implanted in one of the vertebrae;
a second elongate element slidable over said first elongate element, said second elongate element having a second proximal end portion and a second distal end portion; and
said first proximal end portion comprising a keyed outer surface having a non-circular cross-sectional shape;
wherein said second distal end portion is slidable over at least part of said split portions thereby preventing said split portions from deforming away from one another; and
wherein said second distal end portion is slidable away from said split portions to an extent to allow said split portions to deform away from one another; and
a linking member for linking the derotator member to a transverse member, said linking member comprising:
a third distal end portion and a third proximal end portion;
said third distal end portion comprising an opening having a keyed inner surface configured to mate with said keyed outer surface of said first proximal end portion, said keyed inners surface being multifaceted and permitting selection from more than two different angular orientations of said linking member relative to a transverse axis of said derotator member, wherein said linking member is maintained in a selected angular orientation once engaged with said derotator member at the selected angular orientation.

US Pat. No. 10,213,230

RECOVERY AND PROCESSING OF HUMAN EMBRYOS FORMED IN VIVO

Previvo Genetics, LLC, S...

1. A kit for removing blastocysts from a woman's uterus and causing corpus luteum apoptosis, consisting of:a uterine lavage catheter configured for insertion into the woman's uterus to remove one or more blastocysts from the uterus;
one or more first containers for storing one or more of biopsied trophectoderm cells or an inner cell mass recovered from the one or more blastocysts following a biopsy procedure to remove the one or more of the biopsied trophectoderm cells or the inner cell mass from the one or more blastocysts;
one or more second containers for storing and cryopreserving the one or more blastocysts following the biopsy procedure, wherein the one or more first and second containers each comprise one or more labels for identifying the one or more of the biopsied trophectoderm cells or the inner cell mass and the one or more blastocyst from which said one or more of the biopsied trophectoderm cells or said inner cell mass was removed; and
one or more third containers with a sufficient dosage amount of a composition suitable to cause corpus luteum apoptosis leading to desynchronization of the endometrium of the uterus.

US Pat. No. 10,213,229

LEAD INSERTION DEVICES AND ASSOCIATED SYSTEMS AND METHODS

Nevro Corp., Redwood Cit...

1. A method for percutaneously implanting medical devices in a patient, the method comprising:inserting or instructing insertion of a cannula into a patient, wherein the cannula includes a lumen;
inserting or instructing insertion of a preceding dilator into the patient via the lumen of the cannula;
removing or instructing removal of the cannula;
inserting or instructing insertion of a subsequent dilator into the patient via advancement of the subsequent dilator over the preceding dilator;
removing or instructing removal of the preceding dilator;
inserting or instructing insertion of a first medical device and a second medical device side by side into a final dilator; and
advancing or instructing advancement of the first medical device and the second medical device into the patient.

US Pat. No. 10,213,228

CANNULA AND METHODS OF USE

1. A surgical instrument, comprising:a cannula including a proximal first end, an opposite distal second end, a body portion extending between the proximal first end and the distal second end, a first flange portion provided adjacent the proximal first end, and a second flange portion provided between the first flange portion and the distal second end, and a cavity extending through the body portion between the proximal first end and the distal second end;
a collar including a first engagement portion and a second engagement portion attached to one another, the first engagement portion being coupled to the body portion between the first flange portion and the second flange portion, and the second engagement portion including an extension portion and a first locking element provided on the extension portion; and
a patient attachable ring including a platform portion, a first passageway extending through the platform portion, and a second locking element formed on the platform portion, the first passageway having a central axis and being configured to receive portions of the cannula therethrough, and the first locking element being configured to engage the second locking element to control the position of the cannula relative to the patient attachable ring, the second locking element including a first wall portion having a first interior surface and a second exterior surface, a second wall portion having a second interior surface and a second exterior surface, a plurality of first slots formed in the first wall portion and spaced apart from one another, and a plurality of second slots formed in the second wall portion and spaced apart from one another, the first wall portion being closer to the central axis than the second wall portion, and respective ones of the first slots and the second slots being aligned with one another, a first portion of the extension portion adjacent the first locking element being receivable either within one of the first slots or within one of the respective ones of the first and second slots, the first locking element being in a first position contacting the first interior surface of the first wall portion when the first portion of the extension portion is received in one of the first slots, and the first locking element being in a second position contacting the second exterior surface of the second wall portion when the first portion of the extension portion is received in one of the respective ones of the first and second slots, wherein movement between the first position and the second position of the first locking element changes the radial position of the cannula relative to the central axis.

US Pat. No. 10,213,227

TRANSCATHETER DEVICE FOR THE ABLATION OF CALCIFIED TISSUE AT THE FLAPS OF AN AORTIC VALVE

1. A transcatheter device for ablation of calcified tissue at leaflets of an aortic valve comprising:a catheter having a soft body and having a soft and flexible endpiece configured to engage with a guide wire and suitable for passing through the leaflets where the calcified tissue needs to be removed;
a cutting system attached to the endpiece and including two motorized rotary cutting heads arranged coaxially one above the other; and
a vacuum suction device arranged in combination with the cutting system, wherein
one of the motorized rotary cutting heads is located at an end of the endpiece and is configured to remove the calcified tissue and to perform a rough cut by grinding, and
the other one of the motorized rotary cutting heads is configured to perform a fine cut by grinding,
the endpiece having an adjustable guide for engaging with the calcified tissue during the ablation performed by the cutting system and for applying a spiral path effect to the endpiece.

US Pat. No. 10,213,226

TISSUE-REMOVING CATHETER INCLUDING URGING MECHANISM

Covidien LP, Alpine, MA ...

1. A tissue-removing catheter for removing tissue from a wall of a body lumen during a cutting operation thereof, the tissue-removing catheter comprising:an elongate catheter body configured for insertion into the body lumen, the catheter body having opposite distal and proximal portions, and a longitudinal axis extending between the distal and proximal portions, the catheter body having a jogged portion configured to apply an urge force against the body lumen wall and urge a portion of the catheter body toward a portion of the body lumen wall;
a tissue-removing element for removing tissue from the body lumen during the cutting operation, the tissue-removing element being located generally adjacent the portion of the catheter body that is urged toward the body lumen wall by the jogged portion;
an urging mechanism configured to selectively apply a compressive load to the catheter body to adjust the bending stiffness of the jogged portion and the urge force applied by the jogged portion,
wherein the catheter body is configured to retain the shape of the jogged portion when the urging mechanism is applying a compressive load to the catheter body.

US Pat. No. 10,213,225

ROBOTIC DEBRIDEMENT APPARATUSES, AND RELATED SYSTEMS AND METHODS

ELWHA LLC, Bellevue, WA ...

1. A robotic debridement apparatus, comprising:a housing including a bottom;
at least one locomotive mechanism positioned in or on the housing, the at least one locomotive mechanism configured to generate a self-propelling locomotive force; and
at least one debriding tool associated with the housing, the at least one debriding tool positioned on the housing to debride tissue of a wound region on an exterior of an individual that is adjacent to or below the bottom of the housing.

US Pat. No. 10,213,224

CLEANING DEVICE FOR CATHETER AND CATHETER INCLUDING THE SAME

1. A cleaning device for cleaning a catheter comprising a catheter body having a distal end portion defining a catheter lumen and proximal and distal openings in fluid communication with the catheter lumen, the cleaning device comprising:a flushing chamber having opposite proximal and distal ends, a flushing lumen extending between the proximal and distal ends, and an inlet port in fluid communication with the flushing lumen, wherein the flushing lumen is configured to accept the distal end portion of the catheter body therein through the proximal end thereof;
a proximal duckbill seal sealingly received in the flushing lumen at a location proximal of the inlet port, the proximal duckbill seal including a pair of opposing duckbill members configured to slidingly accept therebetween the distal end portion of the catheter body to form a proximal fluid seal about the catheter body at a location proximal of the inlet port; and
a distal duckbill seal sealingly received in the flushing lumen at a location distal of the inlet port such that the inlet port is located between the proximal duckbill seal and the distal duckbill seal, the distal duckbill seal being configured to form a distal fluid seal about the catheter body, the distal duckbill seal including a pair of opposing duckbill members configured to slidingly accept therebetween the distal end portion of the catheter body to form the distal fluid seal about the catheter body;
wherein each of the proximal fluid seal and the distal fluid seal is configured to prevent fluid in the flushing lumen from passing therethrough,
wherein the pair of opposing duckbill members defines a tapered distal end of the proximal duckbill seal,
wherein the pair of opposing duckbill members of the distal duckbill seal defines a tapered proximal end of the distal duckbill seal.

US Pat. No. 10,213,223

ARTHROSCOPIC SURGERY METHOD FOR ANKLE LIGAMENT RECONSTRUCTION

OLYMPUS CORPORATION, Tok...

1. An arthroscopic surgery method for ankle ligament reconstruction comprising:a probe that defines a longitudinal axis and transmits ultrasonic vibration; and
a treating portion provided on a distal portion of the probe, the treating portion including a distal surface that intersects with the longitudinal axis, a first projection that projects from the distal surface along the longitudinal axis, and a plurality of second projections that project from the distal surface along the longitudinal axis and have a shorter projecting length than the first projection,
the method comprising:
forming a guide hole in each of a fibula, a talus, and a calcaneus;
inserting the first projection into the formed guide hole;
moving the first projection along the guide hole so that a bone hole that is larger than the guide hole is formed in each of the fibula, the talus, and the calcaneus by the second projections that outputs the ultrasonic vibration; and
fixing a tendon to the formed bone hole.

US Pat. No. 10,213,222

METHODS FOR THREAD TRANSECTION OF A SOFT TISSUE

1. A method for transecting a soft tissue within a body, comprising the steps of:providing a flexible thread-like cutting element having a smooth and non-abrasive surface;
providing a first and a second hollow introducer needle, each having a lumen extending therethrough, one of said needles having an internal diameter sufficient to receive said cutting element and having an external diameter capable to be inserted into the lumen of the other needle;
extending the first hollow introducer needle into the body at a first location transversely adjacent said soft tissue and keeping the first introducer needle inside of the body on a first side of the soft tissue and near a second location transversely adjacent to the soft tissue and opposite the first location;
extending the second introducer needle into the body at the second location and engaging the second introducer needle with the first introducer needle inside the body by inserting the introducer needle into the lumen of the other introducer needle;
extending the cutting element through the lumens of the first and second hollow introducer needles to leave a first end portion of the cutting element projecting proximally and a second end portion projecting distally from the first and second locations respectively;
retracting the first introducer needle from the body so as to leave the cutting element in place;
retracting the second introducer needle from the body so as to leave the cutting element in place;
routing the cutting element transversely adjacent to the soft tissue so as to traverse the soft tissue on a second side thereof opposite the first side;
looping the cutting element about the soft tissue with the first and the second end portions of the cutting element extending out of the body at either the first location or second location; and
exerting force on the first and the second end portions of the cutting element so as to achieve a kerf-less transection of the soft tissue.

US Pat. No. 10,213,221

SURGICAL INSTRUMENTS INCLUDING CAM SURFACES

COVIDIEN LP, Mansfield, ...

1. A surgical instrument, comprising:a housing;
a handle pivotably connected to the housing;
an elongated shaft extending distally from the housing and defining a longitudinal axis;
an end effector assembly disposed adjacent a distal end of the elongated shaft, the end effector assembly including a first jaw member and a second jaw member, at least one of the jaw members being movable with respect to the other jaw member from a spaced-apart position to a position closer to one another for grasping tissue;
a drive assembly disposed at least partially within the housing, the drive assembly including a drive bar extending at least partially through the elongated shaft such that longitudinal translation of the drive bar causes the jaw members to move between the spaced-apart position and the closer position for grasping tissue; and
an extension connected to and extending from the handle, wherein the extension includes a proximal surface having a first proximal cam portion defining a first angle with respect to the longitudinal axis and a second proximal cam portion defining a second angle with respect to the longitudinal axis, each of the first proximal cam portion and the second proximal cam portion configured to contact a first portion of the drive assembly such that movement of the handle with respect to the housing causes longitudinal translation of the drive bar, wherein a distal surface of the first portion of the drive assembly is rounded, wherein initial actuation of the handle from a non-actuated position causes the first proximal cam portion to contact the first portion of the drive assembly causing a first movement of the at least one jaw member, and wherein subsequent actuation of the handle causes the second proximal cam portion to contact the first portion of the drive assembly causing a second movement of the at least one jaw member.

US Pat. No. 10,213,219

TARGETING GUIDE ASSEMBLY

ARTHREX, INC., Naples, F...

1. A targeting guide assembly, comprising:a first bracket;
a second bracket rotatable relative to said first bracket;
a cannula guide body movable along a curvilinear path within a slot formed in said first bracket, wherein the slot extends between a first arm and a second arm of the first bracket, the slot including a track formed in the first arm, and the track is configured to guide movement of the cannula guide body along the curvilinear path;
a cannula received within a bore of said cannula guide body; and
a cannula sleeve received within said cannula.

US Pat. No. 10,213,218

SLEEVE PIN ASSEMBLY FOR FIXING BONE PIECES

SOLCO BIOMEDICAL CO., LTD...

1. A sleeve pin assembly for fixing a plurality of bone pieces, the sleeve pin assembly comprising:a pin having a fixing portion;
a collet portion detachably coupled to the pin;
a fastening portion having one end connected to the collet portion and the other end that can be fastened to an electric drill; and
a sleeve comprising an internal receiving space to receive the collet portion
wherein the fixing portion of the pin has a through-hole that penetrates a cable, and wherein a plurality of the pins inserted into the plurality of bone pieces are connected to the cable inserted into the through holes.

US Pat. No. 10,213,217

ADJUSTABLE DRILL DEPTH GUIDE

EBI, LLC, Parsippany, NJ...

1. A method of adjusting a length of a drill depth guide, the method comprising:providing an adjustable drill depth guide comprising:
a first sleeve having a helical slot;
a second sleeve at least partially disposed within the first sleeve, the second sleeve having a proximal end;
a radially extending stop member coupled to the second sleeve and operably disposed within the helical slot;
a surface-contacting sleeve rotatably coupled to the first sleeve and axially locked with the first sleeve, the surface-contacting sleeve having a distal end; and
a biasing member biasing the second sleeve in a first axial direction of the surface-contacting sleeve, wherein the biasing member biases the second sleeve in the first axial direction toward the distal end of the surface-contacting sleeve;
moving the radially extending stop member in a second axial direction opposite the first axial direction; and
rotating the second sleeve relative to the first sleeve to move the radially extending stop member in a least one of the first axial direction and the second axial direction to change a distance between the proximal end and the distal end.

US Pat. No. 10,213,216

METHOD AND APPARATUS FOR PROVIDING ARTHROSCOPIC MICROFRACTURE THERAPY

Pivot Medical, Inc., Sun...

1. A method for providing therapy to anatomy of a patient and attaching soft tissue to a bone of the patient, wherein the anatomy comprises an acetabulum, wherein the acetabulum comprises an acetabular shelf on a first side of the acetabulum and the acetabular cup on a second side of the acetabulum, wherein the acetabular cup comprises a cortical bone bed, wherein cancellous bone extends between the acetabular shelf and the cortical bone bed, the method comprising:forming a first bone hole, wherein the first bone hole is formed by entering at the acetabular shelf on the first side of the acetabulum, passing through the cancellous bone and exiting at the cortical bone bed on the second side of the acetabulum, such that blood may flow from the cancellous bone to a surface of the cortical bone bed on the second side of the acetabulum, whereby blood may clot at the surface of the cortical bone bed on the second side of the acetabulum;
forming a second bone hole, wherein the second bone hole is formed by entering at the acetabular shelf on the first side of the acetabulum, passing through the cancellous bone and exiting at the cortical bone bed on the second side of the acetabulum, such that blood may flow from the cancellous bone to the surface of the cortical bone bed on the second side of the acetabulum, whereby blood may clot at the surface of the cortical bone bed on the second side of the acetabulum; and
attaching soft tissue to the cortical bone bed on the second side of the acetabulum, wherein the soft tissue is attached to the cortical bone bed on the second side of the acetabulum by (i) passing a suture into the first bone hole from the acetabular shelf on the first side of the acetabulum and out at the cortical bone bed on the second side of the acetabulum, (ii) passing the suture through the soft tissue on the second side of the acetabulum, and (iii) withdrawing the suture from the cortical bone bed on the second side of the acetabulum, through the second bone hole and out at the acetabular shelf on the first side of the acetabulum so that a first leg of the suture extends into the first bone hole from the acetabular shelf on the first side of the acetabulum and out of the cortical bone bed on the second side of the acetabulum, an intermediate portion of the suture extends through the soft tissue positioned at the cortical bone bed on the second side of the acetabulum, and a second leg of the suture extends into the second bone hole from the cortical bone bed on the second side of the acetabulum and out of the acetabular shelf on the first side of the acetabulum.

US Pat. No. 10,213,215

SYSTEMS AND METHODS FOR PREPARING BONE VOIDS TO RECEIVE A PROSTHESIS

Howmedica Osteonics Corp....

1. A method of performing a revision arthroplasty of a proximal tibia comprising:Removing a previously implanted prosthesis through the proximal tibia;
reaming an intramedullary canal of through the proximal tibia with an intramedullary reamer to form a central bone void, the intramedullary reamer having a stem extending from a cutting portion of the intramedullary reamer and through the central bone void in the proximal tibia;
inserting a trial member of a reamer assembly into the tibia and over the stem of the intramedullary reamer such that the stem of the intramedullary reamer extends through the trial member, the reamer assembly having a support member extending from the trial member while the trial member is positioned within the proximal tibia and over the stem of the intramedullary reamer and an offset reamer rotatably and slidably mounted to the support member such that the offset reamer extends along a longitudinal axis in a direction toward the trial member;
reaming into the proximal tibia with the offset reamer to form an offset bone void that intersects the central void; and
implanting a void filling prosthesis into the central and offset voids, the void filling prosthesis having a body and a lobe portion, the body corresponding with the central bone void and having an opening extending therethrough, the lobe portion extending from the body and corresponding with the offset bone void.

US Pat. No. 10,213,214

METHOD TO STOP BLEEDING, WITH SHORT HEMOSTASIS DURATION USING A LOW DOSE OF ANTICOAGULANT

VASOINNOVATIONS, INC., S...

1. A method of reducing a dosage of an anticoagulant when performing a catheterization procedure at an access site of a radial artery, comprising:(a) administering the anticoagulant at a dose less than a conventional dose of an equivalent of 50 units of unfractionated heparin per kg of body weight;
(b) reducing a contact time of blood at the access site of the radial artery by increasing a velocity of blood in the radial artery, said velocity of blood being increased by increasing a flow of blood in the radial artery, wherein the flow of blood in the radial artery is increased by applying an ulnar pressure on an ipsilateral ulnar artery at an ulnar pressure site by inflating at least a first bladder to compress the ulnar artery fully;
(c) maintaining the contact time of blood at a reduced level for a period of time during the catheterization procedure;
(d) applying a radial pressure on the radial artery by inflating at least a second bladder at the access site to stop bleeding at the access site;
(e) continuing to apply the radial pressure on the radial artery for a duration of time at least until hemostasis of the radial artery is attained;
(f) continuing to apply the ulnar pressure on the ulnar artery at the ulnar pressure site to compress the ulnar artery fully for a first period of time, wherein the first period of time is either about 15 minutes or about 30 minutes; and
(g) attaining hemostasis of the radial artery.

US Pat. No. 10,213,213

APPARATUS AND METHOD TO STOP BLEEDING

VASOINNOVATIONS INC., So...

17. A hemostatic device comprising:a band adapted to be wrapped around a limb of a patient at a puncture site on the limb where bleeding is to be stopped;
a fastener for securing the band in a wrapped state to the patient's limb;
a compression member having an inner peripheral side, the compression member made of a material such that the compression member is more rigid than the band, and at least a portion of which is curved toward the inner peripheral side;
the compression member possessing a first curved portion in a first half of the compression member located between a center and a first end of the compression member, a second curved portion in a second half of the compression member located between the center and a second end of the compression member, and an axis traversing from the first end of the compression member, through the center, to the second end of the compression member;
at least a first balloon provided on the inner peripheral side in the first half of the compression member, the first balloon comprising a plurality of linear sides and is connected to the band by a first connector only on a first linear side of the first balloon, wherein the first linear side of the first balloon is perpendicular to the axis of the compression member;
at least a second balloon provided on the inner peripheral side in the second half of the compression member, the second balloon comprising a plurality of linear sides and is connected to the band by a second connector only on a first linear side of the second balloon; and
a sleeve including a double layer construction defining a compression member holder, and the compression member is positioned in a gap in the double layer construction such that the compression member is held in the compression member holder of the band.

US Pat. No. 10,213,212

METHOD OF TRANSRADIAL CATHETERIZATION, DEVICE FOR ULNAR ARTERY COMPRESSION, AND METHOD OF USE

VASOINNOVATIONS INC., So...

1. A method of obtaining hemostasis of a radial artery of a patient after performing a catheterization procedure at an access site of the radial artery, comprising performing the following steps:(a) applying hemostatic pressure to the radial artery at the access site;
(b) providing an increased flow of blood in the radial artery; and
(c) maintaining simultaneously the hemostatic pressure and the increased flow of blood in the radial artery at least until hemostasis of the radial artery is achieved; wherein step (b) comprises continuously applying an ulnar pressure to an ulnar artery at an ulnar pressure site whereby the ulnar pressure only partially compresses the ulnar artery.

US Pat. No. 10,213,211

MEDICAL DEVICE AND METHODS FOR BLOOD VESSEL COMPRESSION

INSTYTUT KARDIOLOGII, Wa...

1. A medical device comprising:a body for blood vessel compression, said body comprising an elongated cylindrical tube which is hollow and open-ended, and wherein endings of the body are beveled,
a holding element—for attaching the body to a patient's limb at a contact site of the body with the patient's limb by wrapping the holding element around the patient's limb and the body at least once,
a fastening means situated on the holding element for holding the device in a desirable position on the patient's limb,
wherein the body comprises:
a first compression area for applying the compression force to the blood vessel at the contact site situated within the first compression area, said first compression area being situated at the outer surface of the body,
at least one second compression area through which the body is pressed with the holding element against patient's limb, and
a third compression area adapted to be pressed manually for compression control during application of the device onto the patient's limb, wherein said third compression area being situated inside the body, and
wherein the holding element is attached to the body in the proximity of the first compression area.

US Pat. No. 10,213,210

VESSEL CLOSURE SYSTEM

VOSTRA-MED AG, Cham (CH)...

1. A vessel closure system that closes an open vessel in a body, comprising:elastic holding bands, each of the holding bands having a lower side and an exposed upper side;
a closure element coupled to and arranged between the holding bands, the closure element having a lower side and an exposed upper side, the upper side of the holding bands and the upper side of the closure element being an upper side of the closure system;
first, second and third pressure bodies arranged entirely on the lower side of the closure element and each defining an elongate pressure surface, each of the first, second and third pressure bodies having a curvature projecting outwardly from the closure element such that lateral sides of the first, second and third pressure bodies are closer to the closure element than a middle region of the first, second and third pressure bodies between the lateral sides, each of the first, second and third pressure bodies having a rectangular shape with first and second opposed edge regions, the first and second edge regions being adjacent a respective one of the holding bands; and
a skin adhesive layer arranged on the lower side of each of the holding bands such that the skin adhesive layer and the first, second and third pressure bodies are on a common side of the closure system,
the first, second and third pressure bodies in combination having an anatomical shape of three elongate fingers which are alongside one another the first, second and third pressure bodies each constituting one of the three elongate fingers, the first pressure body being adjacent a first lateral side of the closure element, the second pressure body being adjacent a second lateral side of the closure element opposite the first lateral side of the closure element, and the third pressure body being situated between the first and second pressure bodies and having a larger height in a middle region than a height of the first and second pressure bodies in a middle region,
the first, second and third pressure bodies having an outer surface that constitutes an outer patient-contacting surface of the vessel closure system and has skin and body compatibility properties that enable the first, second and third pressure bodies to directly contact skin and body of the patient,
whereby when the vessel closure system is placed on an open, punctured vessel, the skin adhesive layer is adhered to the skin of the patient with the first, second and third pressure bodies situated at a puncture site within the vessel and the outer surface of the first, second and third pressure bodies in contact with the skin of the patient.

US Pat. No. 10,213,209

OCCLUDING DEVICE AND METHOD OF OCCLUDING FLUID FLOW THROUGH A BODY VESSEL

COOK MEDICAL TECHNOLOGIES...

1. A method of occluding fluid flow through a lumen of a body vessel, the method comprising:deploying a first portion of an occluding device at a desired point of occlusion in the body vessel, the occluding device comprising a primary coil having a primary body with a plurality of primary loops and fibers attached to the primary coil and extending therefrom, the occluding device forming a secondary coil defining a plurality of secondary loops, wherein the fibers are wedged between the primary loops and held between the primary loops by an initial tension in the primary coil, the fibers not being looped about turns of the primary loops, wherein the coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed, wherein the initial tension represents the amount of force necessary to cause a 4 centimeter length of the coil to begin to elongate;
ascertaining a position of the first portion relative to the desired point of occlusion in the body; and
deploying a remaining portion of the occluding device to pack the secondary loops together to occlude the lumen, if the first portion is at the desired point of occlusion in the body.

US Pat. No. 10,213,208

TOROIDAL BALLOON FOR EXTERNAL OR INTERNAL COMPRESSION WITH UNIQUE INSERTION OR REMOVAL

1. A urethral catheter comprising:a tube having a retention balloon at distal end;
a toroidal balloon constructed over a portion of the tube, an internal balloon surface of the toroidal balloon contacting outside of the tube and an external balloon surface of the toroidal balloon configured to contact an urethral wall, the toroidal balloon configured to be deployable in the urethra in a deflated or partially inflated state and not covering the retention balloon; and
a first pressure means to inflate the retention balloon when deployed in a bladder and to deflate the retention balloon upon completion of a urethral procedure;
a second pressure means attached to the tube to inflate the toroidal balloon,
the deflated retention balloon extractable via an inversion of the toroidal balloon's internal balloon surface and external balloon surface, with such inversion allowing low friction extraction of the retention balloon without sliding of the external balloon surfaces when contacting the urethral wall.

US Pat. No. 10,213,207

SEPTAL OCCLUSION DEVICES AND METHODS

CVDevices, LLC, San Dieg...

6. A device, comprising:an elongate covering;
a catheter positioned at least partially within the covering, the catheter having a first occluder removably affixed thereto and a second occluder slidably engaged upon the catheter, the first occluder located proximal of the second occluder, the second occluder comprising a throughbore, the throughbore possessing flaps that prevent fluid from passing through the throughbore and are configured to form a leak-free barrier;
a stabilizer positioned at least partially around the catheter; and
wherein the first occluder and the second occluder, when positioned on opposite sides of a septum and covering an opening of the septum, decrease blood flow through the opening.

US Pat. No. 10,213,206

GAS POWERED SYSTEM FOR PERFORMING REMOTE ISCHEMIC CONDITIONING

CellAegis Devices Inc., ...

1. A device for remote ischemic conditioning comprising:an inflatable cuff configured to encircle a limb of a user;
multiple cartridges fluidly coupled to the cuff at one time for providing a source of gas to the cuff;
a manifold providing fluid communication between all of the cartridges and the cuff;
a plurality of first valves disposed between the cartridges and the cuff to control a flow of gas from the cartridges to the cuff, each first valve being associated only with a respective one of the cartridges, each first valve being selectively opened or closed to control a flow of gas only from its respective cartridge;
a second valve in fluid communication with the cuff which, when opened, allows gas in the cuff to escape from the cuff; and
a controller configured to selectively open the first valves to permit a flow of gas from each respective cartridge in a desired sequence to the cuff to implement a remote ischemic conditioning treatment having more than one cycle, each cycle having at least one period of ischemia and one period of reperfusion;
wherein each cartridge is associated with a different cycle in the remote ischemic conditioning treatment to produce ischemia during an ischemic period.

US Pat. No. 10,213,205

T-SLOT TILT ANVIL FOR CIRCULAR STAPLING INSTRUMENT

Covidien LP, Mansfield, ...

1. A surgical stapling device for joining tissue portions, comprising:a handle assembly;
an elongate body extending from the handle assembly;
a cartridge assembly supported on a distal end of the elongate body, the cartridge assembly including a staple cartridge containing a plurality of surgical staples in an annular array;
an anvil assembly at a distal end of the surgical stapling device, the anvil assembly having a shaft for removably coupling the anvil assembly to the cartridge assembly and a head pivotally mounted to a distal end of the shaft, the anvil assembly translatable relative to the cartridge assembly between a first position, where the anvil assembly is spaced from the cartridge assembly, and a second position, where the anvil assembly is approximated relative to the cartridge assembly for clamping tissue disposed therebetween, the head of the anvil assembly transitionable between a first condition, where a tissue contacting surface of the head is substantially perpendicular to the shaft, and a second condition, where the tissue contacting surface of the head is tilted relative to the shaft; and
an anvil sleeve including an elongate portion slidably disposed about the shaft of the anvil assembly and an arm extending from the elongate portion, the anvil sleeve being transitionable between a first position, where the elongate portion of the anvil sleeve is engaged to the head of the anvil assembly to secure the head in the first condition, and a second position, where the elongate portion of the anvil sleeve is spaced from head of the anvil assembly to allow the head to transition to the second condition, the arm being configured to engage the anvil head when the anvil sleeve transitions to the second position to transition the anvil head to the second condition;
wherein the arm includes at least one protrusion configured for releasable engagement with a recess of the anvil head to inhibit transitioning of the anvil sleeve relative to the anvil assembly from the first position to the second position.

US Pat. No. 10,213,204

MICRO SURGICAL INSTRUMENT AND LOADING UNIT FOR USE THEREWITH

Covidien LP, Mansfield, ...

1. A loading unit configured for engagement with a surgical instrument, the loading unit comprising:a proximal body portion;
an end effector disposed in mechanical cooperation with the proximal body portion, the end effector including a cartridge assembly and an anvil assembly, one of the cartridge assembly and the anvil assembly being movable with respect to the other of the cartridge assembly and the anvil assembly between an open position and an approximated position to capture tissue therebetween, the cartridge assembly configured to house fasteners therein;
an actuation sled longitudinally translatable within the cartridge assembly; and
pushers disposed within the cartridge assembly, the pushers arranged in first and second rows, each pusher including a camming surface configured for engagement with the actuation sled, wherein the camming surface of each pusher in the first row lies within a common longitudinal axis as the camming surface of each pusher in the second row, the first row of pushers laterally offset from the second row of pushers.

US Pat. No. 10,213,203

STAPLE CARTRIDGE ASSEMBLY WITHOUT A BOTTOM COVER

Ethicon LLC, Guaynabo, P...

1. A staple cartridge assembly for use with a surgical stapler, wherein said staple cartridge assembly comprises:a cartridge body, comprising:
a proximal end;
a distal end;
a deck;
a longitudinal slot defined in said deck extending from said proximal end toward said distal end; and
staple cavities, wherein said staple cavities are arranged in longitudinal rows, and wherein each said staple cavity comprises:
a top opening defined in said deck;
a bottom opening;
a proximal end;
a distal end; and
a staple cavity sidewall extending between said proximal end and said distal end; and
staples removably stored in said staple cavities, wherein each said staple comprises:
a proximal leg;
a distal leg;
a base extending between said proximal leg and said distal leg; and
a retention projection extending from said base,
wherein said retention projections of said staples are engaged with said staple cavity sidewalls to prevent said staples from falling out of said bottom openings of said staple cavities.

US Pat. No. 10,213,202

METHODS AND SYSTEMS FOR DETECTING STAPLE CARTRIDGE MISFIRE OR FAILURE

INTUITIVE SURGICAL OPERAT...

1. A method of controlling a surgical stapler system, comprising:in response to input at a drive system, transmitting an actuation force to actuate a surgical instrument end effector to perform a stapling procedure, the surgical instrucment end effector comprising a removable staple cartridge;
measuring the transmitted actuation force; and
controlling continued transmission of the actuation force to the end effector based on a comparison of the measured actuation force to a range defined from a minimum threshold actuation force to a maximum threshold actuation force.

US Pat. No. 10,213,201

STAPLING END EFFECTOR CONFIGURED TO COMPENSATE FOR AN UNEVEN GAP BETWEEN A FIRST JAW AND A SECOND JAW

Ethicon LLC, Guaynabo, P...

1. A staple cartridge for use with a surgical stapler including an anvil, said staple cartridge comprising:a cartridge body, comprising:
a proximal end;
a distal end;
a deck;
a longitudinal slot defined in said deck;
a longitudinal row of staple cavities; and
a base;
staples removably stored in said longitudinal row of staple cavities;
a longitudinal row of staple drivers movable between an unfired position and a fired position to drive said staples toward the anvil; and
a firing system movable toward said distal end during a staple firing stroke to sequentially move said staple drivers between said unfired position and said fired position, wherein said longitudinal row of staple drivers comprises:
a first staple driver comprising a first bottom drive surface configured to be driven by said firing system and a first support surface configured to drive a first said staple toward the anvil, wherein a first driver distance is defined between said first bottom drive surface and said first support surface, and wherein said first bottom drive surface is positioned a first support height distance from said base; and
a second staple driver comprising a second bottom drive surface configured to be driven by said firing system and a second support surface configured to drive a second said staple toward the anvil, wherein a second driver distance is defined between said second bottom drive surface and said second support surface, wherein said second driver distance is different than said first driver distance, wherein said second bottom drive surface is positioned a second support height distance from said base, and wherein said first support height distance is different than said second support height distance prior to said staple firing stroke.

US Pat. No. 10,213,200

TISSUE-CUTTING AND -SEALING FORCEPS

Emory University, Atlant...

1. A forcipate surgical instrument comprising:an instrument body having a proximal end, an intermediate handle portion, and a working portion at a distal end, the instrument body comprising first and second mutually opposed elongate arms;
a grasping assembly; and
a mechanical locking assembly operable to lock the grasping assembly in a closed position when engaged;
wherein the arms of the instrument body are hingedly secured together at the proximal end and compressible towards each other and decompressible away from each other to respectively close and open the grasping assembly at the distal end;
wherein the grasping assembly has first and second elongate jaws, each jaw extending from a respective arm at the distal end and being disposed substantially orthogonal to the handle portion, the jaws being adapted to grasp tissue therebetween when the arms are compressed;
wherein the grasping assembly is adapted to receive a scalpel blade slid along a channel running lengthwise through at least one of the first and second jaws, in order to cut tissue grasped therebetween when the grasping assembly is in a closed position; and
wherein the mechanical locking assembly comprises a notched member disposed on one of the first and second arms and a corresponding hooked member shaped and dimensioned to interlock with the notched member, the locking assembly adapted to activate by sliding the hooked member into position to engage the notched member when the grasping assembly is in the closed position.

US Pat. No. 10,213,199

INTRAORAL STAPLER

1. A surgical stapler, comprising:a barrel extending from a handle assembly, the barrel having a channel extending therethrough, the channel configured to house a staple therein;
the handle assembly configured to advance the staple distally towards a first end of the barrel;
the staple configured to be disposed within a gap in a resting configuration, the gap formed between a track and the barrel, wherein the gap is formed on opposing sides of the channel of the barrel, the track extending longitudinally along a length of the barrel;
wherein a flange of the staple is configured to be positioned within the gap, the staple configured to slide along the track upon via actuation of the handle assembly;
a pair of arms extending from the first end of the barrel,
the pair of arms being continuous with the track such that the staple being advanced remains therein until selectively ejected;
wherein the hair of arms are configured to prepare the staple for attaching by bearing against the flange to bias the staple to a closed position as the staple advances along the pair of arms;
each arm of the pair of arms comprise a slot on a lateral side thereof, the slot adapted transition the staple to an ejected configuration.

US Pat. No. 10,213,198

ACTUATOR FOR RELEASING A TISSUE THICKNESS COMPENSATOR FROM A FASTENER CARTRIDGE

Ethicon LLC, Guaynabo, P...

1. A fastener cartridge assembly, comprising:a cartridge body comprising a plurality of fastener cavities;
a plurality of fasteners, wherein each said fastener is removably positioned in a said fastener cavity;
a tissue thickness compensator releasably secured relative to said cartridge body;
a connector, wherein said connector secures said tissue thickness compensator to said cartridge body at a location, and wherein the location is distal to at least one said fastener cavity;
an actuator configured to overcome said connector when actuated, wherein said actuator overcomes said connector prior to the removal of said fasteners from said fastener cavities; and
a firing element configured to remove said fasteners from said fastener cavities during a firing stroke, wherein said firing element is configured to actuate said actuator during the firing stroke.

US Pat. No. 10,213,197

SUTURE HAVING A RESTRAINING ELEMENT AT AN END AND METHOD AND USE THEREOF

Ethicon LLC, Guaynabo, P...

1. A suture comprising:a suture having a first end and second end and a length therebetween, wherein the length extends along a central axis;
a termination feature at the second end and extending toward the first end; and
a plurality of retainers formed on the surface of the length of suture;
wherein the termination feature comprises a coiled portion of the suture coiled about an empty interior defining a coil axis such that the coiled portion is configured to form a stable anchor for the suture without tying a knot in the suture, wherein the coiled portion includes at least first and second 360-degree loops of the suture, wherein the first and second loops are fixably welded together to form an essentially solid wall of the stable anchor, wherein the coil axis is coaxial with the central axis of the suture.

US Pat. No. 10,213,196

REVERSIBLE SURGICAL SUTURING DEVICE

10. A surgical suturing device comprising:a tubular elongated hollow shaft having a distal and proximal end, the hollow shaft configured to receive and engage on its distal end a removable needle carrier with a hollow curved or corkscrew needle fixed to the needle carrier the needle carrier being attached to a suture compartment adapted to receive and hold a suture spool such that suture can be threaded and fed from the spool through the hollow needle;
the elongated hollow shaft containing an internal drive shaft adapted to engage and rotate the needle carrier, the hollow shaft also containing a locking rod adapted to lock the suture spool in a fixed rotational position, the locking rod having a locked configuration where the suture spool is prevented from rotating, and an unlocked configuration where the suture spool is allowed to rotate;
a squeeze handle removably attached to the proximal end of the elongated hollow shaft, the squeeze handle configured to engage the proximal end of the drive shaft allowing the needle carrier to rotate in a chosen direction in response to squeezing the squeeze handle;
first and second separated adjacent parallel linear gear tracks attached to the squeeze handle cooperating with a circular gear located between the tracks, the tracks switchably configured so that only one of the tracks engages the circular gear, the circular gear attached to the proximal end of the drive shaft, wherein when the squeeze handle is squeezed, the linear gears move in relation to the circular gear causing the circular gear and the drive shaft to rotate.

US Pat. No. 10,213,195

MEDICAL FIXATION DEVICES WITH IMPROVED TORSIONAL DRIVE HEAD

ETHICON, INC., Somervill...

1. A surgical method, comprising:positioning an anti-rotational member that is monolithic with a solid drive head of a medical fixation device within an opening extending through a sidewall of a driver tool to attach the driver tool to the medical fixation device, the drive head being a rectangular block, and the anti-rotational member being a rectangular block having a volume smaller than a volume of the drive head's rectangular block, the anti-rotational member extending proximally from a distal-most end of the solid drive head and extending laterally from the solid drive head such that the drive head is positioned within a distal end of the driver tool when the anti-rotational member is positioned in the opening in the sidewall of the driver tool;
inserting a shank extending distally from the drive head of the medical fixation device through at least one soft tissue segment, the shank having a thread that terminates distal of the solid drive head; and
implanting the shank in bone to anchor the at least one soft tissue segment in the bone.

US Pat. No. 10,213,194

SURGICAL RETRACTION SYSTEMS INCLUDING STERNAL RETRACTORS AND HEMOSTATIC INSERTS

Ethicon, Inc., Somervill...

1. A surgical retraction system comprising:a sternal retractor having a first retractor arm and a second retractor arm;
an insert comprising
a first section having a first rigid backing,
a second section having a second rigid backing that is spaced from said first rigid backing, and
a connector section comprising resilient material interconnecting proximal ends of said first and second sections, wherein said first section of said insert is coupled with said first retractor arm, said second section of said insert is coupled with said second retractor arm, and said connector section of said insert extends laterally between the proximal ends of said first and second sections of said insert.

US Pat. No. 10,213,193

TISSUE RETRACTOR AND METHODS OF USE

Globus Medical, Inc., Au...

1. A surgical system comprising:a retractor system comprising a first retractor blade, a second retractor blade, and a third retractor blade, wherein the first retractor blade comprises an inner wall that forms a part of a channel that extends a length of the first retractor blade,
a shim device attached to the first retractor blade, wherein the shim device is received within the channel of the first retractor blade, wherein the shim device comprises a proximal portion and a distal portion with the distal portion of the shim device being tapered to engage a portion of a vertebral member,
wherein the shim device further comprises a first opening and a second opening, and the first retractor blade comprises a latch mechanism configured to fit within the first opening and the second opening, wherein when the latch mechanism is in the first opening the shim device is in a retracted position and wherein when the latch mechanism is in the second opening the shim device is in an extended position, and
wherein the second opening is configured with a first end and a second end, the second end of the second opening is configured to receive a shim tool.

US Pat. No. 10,213,192

SURGICAL INSTRUMENT AND METHOD OF USE

Warsaw Orthopedic, Inc., ...

1. A surgical instrument comprising:an element connectable with a fixture;
a first member independently and selectively movable relative to the element and including a part engageable with an incision in a cranial-caudal orientation relative to a body to space apart tissue, the part comprising a housing having a first blade and a shaft disposed in the housing, the shaft including an arm and a second blade that is coupled to the arm, the shaft defining a longitudinal axis, the second blade being coupled to the shaft such that the second blade is prevented from translating relative to the shaft along the longitudinal axis, the arm including a flange and a lever that is pivotable relative to the flange to facilitate rotation of the arm about an axis defined by the arm;
a second member independently and selectively movable relative to the element and including a part engageable with tissue of an anterior portion of the incision; and
a third member independently and selectively movable relative to the element and including a part engageable with tissue of a posterior portion of the incision,
wherein the parts are disposable in a configuration to space tissue of the incision to define an oblique surgical pathway relative to a bilateral axis of the body, the element comprising a collar having a splined surface that rotatably engages a splined surface of a collar of the fixture to simultaneously rotate the members relative to the fixture.

US Pat. No. 10,213,191

APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE

ACCESSCLOSURE, INC., San...

1. A method for closing a puncture extending through tissue to a body lumen, comprising:forming a first seal in the puncture, said step of forming a first seal comprising:
inserting an apparatus into a puncture, the apparatus comprising an elongate occlusion member including an expandable member on a distal end thereof; a tubular member slidably disposed around the elongate occlusion member; a sealant disposed within the tubular member adjacent the expandable member; and a stop preventing proximal movement of the tubular member relative to the elongate occlusion member, wherein the apparatus is inserted into the puncture until the expandable member and the sealant extend from the puncture into the body lumen;
radially enlarging the expandable member;
at least partially withdrawing the elongate occlusion member from the puncture until the expanded expandable member contacts a wall of the body lumen adjacent the puncture, thereby withdrawing the sealant back into the puncture;
disengaging the stop, thereby allowing proximal movement of the tubular member relative to the elongate occlusion member; and
exposing the sealant within the puncture by at least partially moving the tubular member proximally after disengaging the stop; and
forming a second seal in the puncture.

US Pat. No. 10,213,190

DEVICE FOR SAMPLING A BIOLOGICAL TISSUE

1. A device for sampling a biological tissue comprising: a rod extending along a longitudinal axis between a proximal end and a distal end, anda guide tube in which the rod is slidably and rotatably arranged therein, comprising a side aperture, wherein the rod comprises
an external surface facing an inner surface of the guide tube,
a capture surface configured to be applied against a biological tissue,
wherein the capture surface is nanoporous or has protrusions adapted for sampling a biological tissue by micro abrasion,
an observation window transparent to visible light, laid out in the external surface, and a longitudinal groove extending into the external surface of the rod, from the proximal end of the rod to the observation window, said groove being configured to receive a bundle of optical fibers,
wherein the observation window and the capture surface are laid out at a same distance from the distal end of the rod and spaced out angularly, so that one of the capture surface and the observation window may face the side aperture depending on the respective angular orientation of the guide tube and of the rod.

US Pat. No. 10,213,189

ECHOGENIC ENHANCEMENT FOR A NEEDLE

BOSTON SCIENTIFIC SCIMED,...

1. A needle, comprising:a longitudinal body extending between a proximal end and a distal end and including a lumen extending therethrough, an outer surface of the body including a plurality of first ultrasound reflecting depressions distributed along at least a portion of a length of the body separated from one another by intervening sections, each of the first depressions extending along a longitudinal axis of the needle from a first end to a second end and including a steep slope portion oriented to reflect ultrasound waves to a first transducer, a shallow slope portion oriented to reflect ultrasound waves back to a second transducer, and a trough including a gradual transition between the steep and shallow slope portions, the trough including an inner surface oriented to reflect ultrasound waves back to a third transducer positioned at an angle between the first and second transducers.

US Pat. No. 10,213,188

HIGH VOLTAGE SWITCHING CIRCUIT AND ULTRASOUND PROBE

SAMSUNG ELECTRONICS CO., ...

1. An ultrasound probe comprising:a transducer; and
a voltage switching circuit configured to control a signal received by the transducer by blocking a signal which has a potential that is greater than a reference potential,
wherein the voltage switching circuit comprises at least one main switching device connected to at least one current source, and a control circuit configured to control a potential difference between respective terminals of each of the at least one main switching device by receiving current from the at least one current source such that the potential difference is within a predetermined range,
wherein the control circuit comprises a first voltage switching device, a second voltage switching device, and a third voltage switching device,
wherein the first voltage switching device and the second voltage switching device are configured to operate in a first voltage range, and
wherein the third voltage switching device is configured to operate in a second voltage range higher than the first voltage range.

US Pat. No. 10,213,187

METHOD AND APPARATUS FOR PERCUTANEOUS SUPERFICIAL TEMPORAL ARTERY ACCESS FOR CAROTID ARTERY STENTING

Mubin I. Syed, Springfie...

1. A system for treatment of strokes due to arteriosclerosis in the carotid arteries, the system comprising:a Superficial Temporal Artery (STA) guidewire comprising a distal end, the distal end formed into a knob and having a bend for steering through rotation of the STA guidewire;
a Femoral Artery (FA) catheter comprising a catheter body and a guidewire, the guidewire comprising a distal end having a snare for mechanical engagement with said knob, the FA catheter withdrawable from the FA with the STA guidewire to provide through and through access to the femoral artery using the STA guidewire;
a STA guidewire insertion needle comprising an opening through which the STA guidewire is insertable;
carotid artery arteriosclerosis interventional device comprising an opening, wherein the carotid artery arteriosclerosis interventional device is deliverable over the STA guidewire through the opening following withdrawal of the FA catheter;
a multi-plane imaging transducer comprising a plurality of individual transducers, the multi-plane imaging transducer enabled for generating a transverse, a sagittal and a coronal image of a region including a superficial temporal artery (STA) using ultrasonic imaging techniques, by individually steering the plurality of transducers of the multi-plane imaging transducer to generate image data of at least a transverse plane, at least sagittal plane and at least a coronal plane; and
an image control and display processor coupled to said multi-plane imaging transducer, the image control and display processor displaying a transverse view, a sagittal view, and a coronal view of the region derived from said transverse plane, sagittal plane and coronal plane image data, wherein the STA guidewire insertion needle is configured to percutaneously penetrate and enter the STA to enable insertion of the STA guidewire through the opening in the STA guidewire insertion needle into the STA, and wherein the STA guidewire, once in the STA, is configured to be guided through the STA tortuosity using the transverse, sagittal and coronal images that provide a relative distance information of the STA, the needle and the STA guidewire within the region to enable an insertion of the STA guidewire and a guidance of the STA guidewire by use of the bend in the STA guidewire, without inadvertently puncturing and creating unwanted trauma to the STA by the needle or the STA guidewire;
wherein the STA guide wire is further configured to be steered, using the bend in the STA guidewire, to the aortic arch from the STA via the external carotid artery (ECA) and the common carotid artery (CCA).

US Pat. No. 10,213,186

IMAGING APPARATUS FOR DIAGNOSIS AND PROBE

TERUMO KABUSHIKI KAISHA, ...

1. An imaging apparatus for diagnosis comprising:a probe unit that includes a sheath and a transmitting and receiving unit located in the sheath, the transmitting and receiving unit transmitting and receiving a signal, the transmitting and receiving unit configured to transmit and receive the signal while rotating inside the sheath in a circumferential direction or while rotating in the circumferential direction and moving in an axial direction, the probe unit including a plurality of deformation portions whose respective cross-sectional shape is deformable in response to an external pressure, the plurality of deformation portions being disposed at different positions of the sheath in the axial direction; and
a computer processor configured to:
calculate at least one parameter at each deformation portion which indicates a deformation degree of the respective deformation portions disposed at the different positions in the axial direction, by using a tomographic image including the deformation portions; and
calculate a value corresponding to a myocardial fractional flow reserve, based on the at least one parameter.

US Pat. No. 10,213,185

ULTRASONIC DIAGNOSTIC APPARATUS

Toshiba Medical Systems C...

1. An ultrasonic diagnostic apparatus comprising:converting circuitry which converts position information of an ultrasonic probe or a scanning line in a first coordinate system into position information in a second coordinate system which is used as a reference coordinate system;
processing circuitry which controls an angle of a scanning line and a focusing distance of a current Doppler measurement at a time of performing Doppler measurement for generating Doppler spectrum data;
memory circuitry which stores an angle of a scanning line and a focusing distance in a past Doppler measurement;
generating circuitry which generates guide data based on first position information obtained in the past Doppler measurement and converted by the converting circuitry, second position information obtained in the current Doppler measurement and converted by the converting circuitry, and the angle of the scanning line and the focusing distance in the past Doppler measurement which are stored by the memory circuitry; and
display control circuitry which displays an image based on the guide data.

US Pat. No. 10,213,184

ULTRASOUND HEAD FRAME FOR EMERGENCY MEDICAL SERVICES

KONINKLIJKE PHILIPS N.V.,...

1. A head frame configured for a head of a medical patient, the head frame comprising:a probe support for a probe configured for imaging, therapy, or both imaging and therapy, wherein the probe support comprises a holder for the probe, wherein the probe support is configured to maintain the probe against the head of the patient in response to a weight of the head resting on the head frame without attaching the holder to the head of the patient; and
a neck support of rigid construction, wherein the neck support is configured to at least partially contact and support a neck of the patient,
wherein the probe support includes a first opening at a first upper end of a first upstanding structure for holding a first probe on a first side of the head and a second opening at a second upper end of a second upstanding structure for holding a second probe on an opposite side of the head,
wherein the probe support has a configuration that wraps around a back of the head of the patient between the first upstanding structure and the second upstanding structure, and wherein the neck support is attachable to and separable from the probe support.

US Pat. No. 10,213,183

THREE-DIMENSIONAL ULTRASONIC IMAGING METHOD AND SYSTEM

Shenzhen Mindray Bio-Medi...

1. A three dimensional ultrasound imaging method, comprising:transmitting ultrasound waves towards a head of a fetus;
receiving ultrasound echoes to obtain ultrasound echo signals;
obtaining a three dimensional volume data of the head of the fetus based on the ultrasound echo signals;
extracting sagittal section characteristic regions from the three dimensional volume data, wherein the sagittal section characteristic regions represent plane regions which have larger gray values than areas located outside both sides of the plane regions;
selecting at least three characteristic points from the sagittal section characteristic regions;
determining a plane comprising the at least three characteristic points;
acquiring a median sagittal section image of the head of the fetus based on the plane; and
displaying the median sagittal section image.

US Pat. No. 10,213,182

DEVICES, SYSTEMS, AND METHODS FOR ASSESSING A VESSEL UTILIZING ANGLED FLOW-SENSING ELEMENTS

VOLCANO CORPORATION, San...

1. A system comprising:a flow-sensing intravascular device that includes:
a flexible elongate member having a proximal portion, a distal portion terminating at a distal tip, and a central longitudinal axis, the flexible elongate member sized and shaped for insertion into human vasculature;
a flow sensing element secured to the distal tip of the flexible elongate member, wherein the flow sensing element is fixedly mounted in a forward facing manner at an oblique angle with respect to the central longitudinal axis of the flexible elongate member;
a pressure sensing element spaced from the flow sensing element and secured to the flexible elongate member proximal to the flow sensing element; and
a rotational monitor configured to determine a rotational position of the flow sensing element; and
a processing unit in communication with the flow-sensing intravascular device and the rotational monitor, the processing unit configured to:
obtain flow measurements from the flow-sensing intravascular device;
determine whether the flow sensing element is oriented toward a wall of a vessel based on the obtained flow measurements;
receive, from the rotational monitor, a communication of the rotational position of the flow sensing element;
output a visual representation of the obtained flow measurements to a display; and
output a visual indication to the display indicating an amount of rotation of the flexible elongate member to cause the flow sensing element to be oriented away from the wall of the vessel, wherein the amount is based on the communication of the rotational position of the flow sensing element provided by the rotational monitor.

US Pat. No. 10,213,181

STETHOSCOPE DIAPHRAGM

3M INNOVATIVE PROPERTIES ...

1. A stethoscope diaphragm comprising:a disc; and
a rim;
wherein the rim comprises:
a wall having a first end and a second end,
a lip extending substantially perpendicularly from the first end of the wall,
a bridge extending substantially perpendicularly from the second end of the wall, and a fork extending from the bridge;
a plurality of features extending from the fork; and wherein the features are formed from holes cut out from a portion of the fork.

US Pat. No. 10,213,180

MULTIPLE-DIMENSION IMAGING SENSOR WITH OPERATION BASED ON MAGNETIC FIELD DETECTION

DENTAL IMAGING TECHNOLOGI...

1. An imaging system comprising:an intra-oral imaging sensor including an image sensing component and a magnetometer; and
an electronic processor configured to
receive an output of the magnetometer indicative of an actual magnetic field that impinges the intra-oral imaging sensor,
compare data indicative of the actual magnetic field based on the output of the magnetometer to data indicative of a first expected magnetic field, wherein the data indicative of the first expected magnetic field includes data indicative of a magnetic field applied by a permanent magnetic positioned proximal to an imaging sensor storage compartment when the intra-oral imaging sensor is placed in the imaging sensor storage compartment for storage, and
alter operation of the imaging system in response to determining, based on the comparison, that the actual magnetic field matches the first expected magnetic field.

US Pat. No. 10,213,179

TOMOGRAPHY APPARATUS AND METHOD OF RECONSTRUCTING TOMOGRAPHY IMAGE

Samsung Electronics Co., ...

1. A method of reconstructing a tomography image, the method comprising:obtaining a plurality of raw data corresponding to a plurality of views by performing a tomography scan on an object;
deblurring the plurality of raw data, based on a point spread function (PSF) that varies according to locations in a field of view (FOV) in a gantry; and
reconstructing a final tomography image in which a motion of the object is corrected from the plurality of deblurred raw data based on a motion vector indicating the motion of the object.

US Pat. No. 10,213,178

CALCULATION OF PERFUSION PARAMETERS IN MEDICAL IMAGING

1. A method of determining a residue function for perfusion at one or more locations in a subject's brain tissue, from a series of medical images of the tissue acquired using a medical imaging modality at successive times after introducing a contrast agent into the subject's blood stream, the method correcting for a leakage of the contrast agent out of the blood stream into extravascular extracellular space (EES) of the tissue, the method comprising:a) providing to a data processor a signal indicating contrast agent concentration as a function of time for one or more voxels of the tissue that exhibit the leakage at a significant level, a signal indicating an average or typical contrast agent concentration as a function of time for non-leaking voxels of the tissue, and an artery input function indicating a concentration of the contrast agent as a function of time in the arteries feeding into the tissue, the signals and artery input function being derived from the images;
b) fitting the signal for the voxels exhibiting leakage to an expected value for the signal as a function of time, using the data processor, according to a model with free parameters including at least a parameter depending on leakage rate, the model assuming that the concentration of contrast agent in the blood perfusing through a voxel has a same shape as a function of time as the average or typical contrast agent concentration for the non-leaking voxels;
c) using the model and best fit leakage rate parameter to find and make an expected correction for leakage, to the signal for contrast agent concentration as a function of time, for the voxels exhibiting leakage, using the data processor; and
d) deconvolving the corrected signal for the voxels exhibiting leakage from the artery input function, to find the residue function for those voxels, using the data processor.

US Pat. No. 10,213,177

X-RAY CT APPARATUS, DATA PROCESSING DEVICE, AND PROJECTION DATA GENERATION METHOD

HITACHI, LTD., Tokyo (JP...

1. An X-ray CT apparatus comprising:a scan gantry unit that emits X-ray to an object, and that detects the X-ray transmitted through the object;
a bed on which the object is laid, and in which the object is loaded into or unloaded from an X-ray emission range of the scan gantry unit; and
an operation desk including a data processing device that controls each portion of the scan gantry unit, that acquires measurement data measured by the scan gantry unit, and that generates an image including an object tomographic image from the measurement data,
wherein the data processing device includes an extraction unit that acquires air data measured using the X-ray CT apparatus and the measurement data obtained by scanning the object, that extracts sensitivity variation data which is a sensitivity variation component of a detection element from the air data, and that extracts blank data from which the sensitivity variation component is removed, and a projection data generation unit that removes the sensitivity variation component and noise which are included in the measurement data, based on the sensitivity variation data, and that uses the blank data so as to perform a correction process of the measurement data from which the sensitivity variation component and the noise are removed.

US Pat. No. 10,213,176

APPARATUS AND METHOD FOR HYBRID PRE-LOG AND POST-LOG ITERATIVE IMAGE RECONSTRUCTION FOR COMPUTED TOMOGRAPHY

TOSHIBA MEDICAL SYSTEMS C...

1. An apparatus, comprising:processing circuitry configured to
obtain projection data representing an intensity of X-ray radiation detected at a plurality of detector elements, the projection data including a plurality of projection images, and each projection image including pixels corresponding to respective detector elements of the plurality of detector elements,
categorize pixels of a projection image of the obtained projection data into a first subset and a second subset, the first subset including one or more pixels of the projection image representing respective detection values that satisfy a predefined criterion, and the second subset including one or more pixels of the projection image representing detection values that do not satisfy the predefined criterion, and
iteratively reconstruct a reconstructed image by adjusting pixel values of the reconstructed image to minimize a value of an optimization function, wherein
the optimization function takes on a pre-log form of the optimization function for pixels in the first subset, and, for pixels in the second subset, takes on a post-log form of the optimization function, which is different from the pre-log form of the optimization function.

US Pat. No. 10,213,175

HEAT SINKING SYSTEM AND IMAGING APPARATUS INCLUDING THE SAME

GE Medical Systems Global...

1. A heat sinking system comprising;an air introducing portion, a capture portion and an air discharge portion, wherein,
the air introducing portion is configured to introduce air from external, and to be in communication with heat sinking space, so that the introduced air flows into the heat sinking space and exchanges heat with a heat sinking object which is accommodated in the heat sinking space;
the capture portion is configured to be in communication with the heat sinking space and the air discharge portion, and to capture air which flows from the heat sinking space to the capture portion and enable the captured air to flow into the air discharge portion;
the air discharge portion is configured to discharge the air which flows in out of the capture portion to the external; and
a first blocking member disposed between the air introducing portion, and the heat sinking space and the capture portion and configured to block the air introduced from the air introducing portion from flowing into the capture portion.

US Pat. No. 10,213,174

NUCLEAR MEDICINE IMAGING SYSTEMS AND METHODS HAVING MULTIPLE DETECTOR ASSEMBLIES

General Electric Company,...

1. A nuclear medicine (NM) imaging system comprising:a gantry including a cavity that is sized and shaped to receive an object therein, the cavity being oriented relative to mutually perpendicular longitudinal, vertical, and horizontal axes, the cavity extending lengthwise along the longitudinal axis;
a plurality of detector assemblies distributed at least partially around the cavity, each of the detector assemblies in the plurality including a movable arm and a detector head that is coupled to the movable arm, the movable arm configured to move the detector head toward and away from the object within the cavity; and
at least one processor configured to execute programmed instructions stored in memory, wherein the at least one processor, when executing the programmed instructions, is configured to:
determine a body contour of the object within the cavity, the body contour representing an exterior surface of the object positioned within the cavity;
determine an acquisition configuration based on the body contour, the acquisition configuration including at least three of the detector heads positioned in a dense group that borders the body contour, the detector heads in the dense group being primary detector heads;
move at least one of the object or one or more of the primary detector heads so that the primary detector heads are in the dense group near the object.

US Pat. No. 10,213,173

WHOLE-BODY SPECT SYSTEM

KONINKLIJKE PHILIPS N.V.,...

1. A nuclear imaging system comprising:a patient support configured to receive a patient and move the patient in an axial direction of the patient;
a gantry including a plurality of adjacent stationary circular or elliptical rings of radiation detectors arranged circumferentially around the patient support in parallel transaxial planes, each radiation detector on the plurality of circular or elliptical rings being tilted with respect to the geometric center of the rings, said tilt being along an axis that is spaced apart from and parallel to the axial direction of the patient, differently in the transaxial plane of the circular or elliptical ring than the radiation detectors at a same radial position in an adjacent circular or elliptical ring such that fields of view of adjacent detectors overlap; and
wherein the radiation detectors include slit-slat collimated radiation detectors, each of the slit-slat collimated radiation detectors including:
at least one slit opening in a sheet of radiation absorbing material with one side of the sheet surface facing the patient support and the at least one slit opening extending in the axial direction, the radiation detectors being circumferentially offset such that the at least one slit opening of each detector is circumferentially offset relative to the slit openings of detectors in the adjacent circular or elliptical ring,
a plurality of parallel slats of radiation absorbing material transaxially oriented relative to the at least one slit, and
an array of detectors in a plane parallel to the sheet and perpendicular to the slats;
one or more processors connected to the plurality of detectors and configured to:
record strikes of gamma photons in the radiation detectors, and
reconstruct the recorded strikes of the gamma photons into a single photon emission computed tomography (SPECT) image.

US Pat. No. 10,213,172

IMAGING METHOD AND SYSTEM OF TUBE VOLTAGE AND CURRENT OPTIMIZATION

General Electric Company,...

1. A method, comprising:executing a low-dose preparatory scan to an object by applying tube voltages and tube currents in an x-ray source;
generating a first image of the object corresponding to the low-dose preparatory scan;
generating at least one of a plurality of image quality estimates and at least one of a plurality of dose estimates view by view at least based on the first image;
optimizing the tube voltages and the tube currents to generate optimal profiles for the tube voltage and the tube current, at least one of the optimal profiles for the tube voltage and the tube current being generated based on at least one of the plurality of image quality estimates and at least one of the plurality of dose estimates, wherein optimizing the tube voltages and the tube currents comprises selecting a constant value from a corresponding value group as the tube voltage or the tube current for one or more views, modulating the tube voltages or the tube currents view by view, or a combination thereof;
executing an acquisition scan by applying the tube voltages and the tube currents based on the optimal profiles; and
generating a second image of the object corresponding to the acquisition scan.

US Pat. No. 10,213,171

X-RAY PHOTOGRAPHY SYSTEM

SHIMADZU CORPORATION, Ky...

1. An X-ray photography device, adapted for performing X-ray photography in multi-directions of a detected body based on a predetermined series of photograph planning, the device comprising:a support unit, for supporting and making an X-ray tube and an X-ray detector face to face, and capable of rotating in rotation directions along and around a body axis of the detected body lying on a bed;
a position detection unit, for detecting actual rotation information about the rotation directions and rotation angles related to positions of the support unit around the detected body;
a plurality of memory switches, respectively arranged in association with the rotation directions;
a target rotation information memory unit, for storing target rotation information about the rotation directions and the rotation angles as targets of the support unit corresponding to the memory switches respectively;
display lamps, arranged in accordance with the memory switches respectively;
a rotation control unit, for reading the target rotation information corresponding to the memory switches operated according to an operation on the memory switches from the target rotation information memory unit and controlling a rotation of the support unit, so as to make the actual rotation information from the position detection unit be consistent with the read-out target rotation information;
a set switch adjacent to the plurality of memory switches;
a set display lamp, arranged in accordance with the set switch; and
a display control unit, for driving the corresponding display lamp of the operated memory switch when the actual rotation information is consistent with the target rotation information,
wherein the display control unit performs a drive control to make the set display lamp of the set switch flash on and off intermittently or turned on before the actual rotation information from the position detection unit is consistent with the target rotation information,
wherein the display control unit drives the corresponding display lamp of the operated memory switch to a turn-on state when the actual rotation information from the position detection unit is consistent with the target rotation information and when a turn-off mode of the X-ray photography device has not been set, and at the same time when the X-ray photography is performed, a state of the display lamp is maintained, and the X-ray photography device performs X-ray photography in multi-directions of a detected body under a same mode.

US Pat. No. 10,213,170

POSITIONING OF PARTIAL VOLUMES OF AN ANATOMY

PLANMED OY, Helsinki (FI...

1. A method for positioning an anatomy for x-ray imaging said method comprising x-ray imaging a first partial volume of the anatomy, wherein in connection with x-ray imaging of the first partial volume, a photograph or a still video image of the anatomy positioned in an imaging station is taken by a camera arranged in connection with the imaging station, wherein said photograph or still video image of said anatomy is presented on a display as a positioning image in which said anatomy is shown at a new position in relation to the imaging station at the time of taking said photograph or still video image and wherein the positioning image and a real time image of the imaging station are then presented on said display one upon another such that the anatomy being x-ray imaged is positioned to meet the new position of the anatomy according to the positioning image using observation of the display such that x-ray imaging of a second partial volume of the anatomy different from the first partial volume is performed.

US Pat. No. 10,213,169

AUTOMATED POSITIONING OF A PATIENT TABLE RELATIVE TO A MEDICAL INSTALLATION

1. A user interface for automated positioning of a patient table relative to a medical installation, the user interface comprising:a display and operating unit configured to output a patient image; and
a microprocessor configured to:
define at least one item of reference location information on the patient table, wherein the at least one item of reference location information is a fixed reference point configured to be used as a marker for table positioning for moving and re-moving the patient table;
represent the at least one item of reference location information in the patient image;
move the patient table or the medical installation with aid of a positioning system, wherein the at least one item of reference location information is brought into alignment with a zero point of a working area of the medical installation;
store, in an electronic memory, the at least one item of reference location information independently of a present position of a patient in an electronic patient file or independently of individual body dimensions of the patient in a scan log,
call up the at least one item of reference location information from the electronic memory at a later time, and
re-move the patient table or the medical installation with the aid of the positioning system, wherein the at least one item of reference location information is again brought into alignment with the zero point of the working area of the medical installation.

US Pat. No. 10,213,168

RECLINING PATIENT CHAIR FOR NUCLEAR MEDICINE SYSTEM

Siemens Medical Solutions...

1. A nuclear radiation imaging system comprising:a patient support having a patient chair, a base, and a joint connected at one end to the base and at the other end to the patient chair, said patient chair having a relatively vertical loading position from which a patient is loaded into said patient chair, and a relatively horizontal imaging position for imaging of a patient loaded into said patient chair, wherein said patient chair pivots about said joint from said relatively vertical loading position to said relatively horizontal imaging position after said patient has been loaded into said patient chair from said relatively vertical loading position;
a pair of nuclear radiation detectors mounted at right angles to each other; and
a gantry including a base unit and an armature, a first end of the armature being rotationally mounted to the base unit such that the armature may rotate with respect to the base unit, a second end of the armature being mounted to said pair of nuclear radiation detectors such that said pair of nuclear detectors may rotate with respect to the armature, and said base unit being mounted to said base and being movable toward and away from said patient chair;
said pair of nuclear radiation detectors being movably mounted to the gantry such that the pair of nuclear radiation detectors may be moved from a patient loading position enabling a patient to be loaded into said patient chair while in said relatively vertical loading position, wherein said patient loading position of said pair of nuclear radiation detectors does not enable imaging of a patient, to a patient imaging position enabling a patient to be imaged by said pair of nuclear radiation detectors,
wherein said patient imaging position of said pair of nuclear radiation detectors does not enable loading of a patient into said patient chair from said relatively vertical loading position.

US Pat. No. 10,213,167

CONTRAST AGENT DOSE SIMULATION

KONINKLIJKE PHILIPS N.V.,...

1. A method, comprising:obtaining a set of energy dependent data generated from a spectral scan, wherein the set of energy dependent data includes a sub-set of data corresponding to only contrast agent;
separating the sub-set of data from other data of the energy dependent data, wherein the other data includes non-contrast agent data;
scaling the sub-set of data to change a concentration of the contrast agent in the sub-set of data from that of the sub-set of data;
visually presenting at least the scaled sub-set of data;
wherein the set of energy dependent data is projection data, and the sub-set of data corresponding to only contrast agent includes contrast agent only projections;
obtaining an administered amount of the concentration; and
linearly scaling the contrast agent only projections by a scaling factor, thereby reducing an amount of contrast agent in the contrast agent only projections.

US Pat. No. 10,213,166

SYSTEMS AND METHODS FOR PROVIDING ENHANCED HAPTIC FEEDBACK

IMMERSION CORPORATION, S...

1. A system comprising:a haptic output device constructed and arranged to generate a haptic effect to a user of the system; and
a chemical delivery device constructed and arranged to physically deliver a chemical to the user of the system, the chemical having a state selected from the group consisting of a solid, a fluid, and combinations thereof.

US Pat. No. 10,213,165

SYSTEMS AND METHODS FOR MEASURING CALORIE INTAKE

Vivint, Inc., Provo, UT ...

1. A computer-implemented method for measuring calorie input, comprising:receiving a pre-consumption image of a food item;
analyzing the pre-consumption image of the food item to determine an amount of the food item;
receiving a post-consumption image of the food item;
determining a consumption amount of the food item based at least in part on the pre-consumption image and the post-consumption image; and
determining a calories consumed value based at least in part on the consumption amount of the food item.

US Pat. No. 10,213,164

METHOD AND APPARATUS FOR UNDER-SAMPLED ACQUISITION AND TRANSMISSION OF PHOTOPLETHYSMOGRAPH (PPG) DATA AND RECONSTRUCTION OF FULL BAND PPG DATA AT THE RECEIVER

QUALCOMM Incorporated, S...

1. A method for signal processing, comprising:generating, using an apparatus, a plurality of sampling times with non-uniform time intervals between adjacent sampling times;
representing, using the apparatus, the plurality of sampling times with non-uniform time intervals between adjacent sampling times with a measurement matrix;
directing, using the apparatus, bursts of energy at a biological tissue during the plurality of sampling times with non-uniform time intervals between adjacent sampling times;
sensing, using the apparatus, samples of a signal, formed at the biological tissue in response to the bursts of energy, during the plurality of sampling times with non-uniform time intervals between adjacent sampling times; and
precoding, using the apparatus, at least some of the sensed samples using the measurement matrix.

US Pat. No. 10,213,162

SYSTEM AND METHOD FOR CAPTURING AND DECONTAMINATING PHOTOPLETHYSMOPGRAPHY (PPG) SIGNALS IN A VEHICLE

Honda Motor Co., Ltd., T...

1. A computer-implemented method for processing photoplethysmography (PPG) signals in a vehicle, comprising:receiving a plurality of PPG waveform signals output from a plurality of optical sensors included in one or more sensor assemblies;
receiving a plurality of pressure measurement signals output from a plurality of pressure sensors included in the one or more sensor assemblies;
selecting optimum PPG waveform signals from the plurality of PPG waveform signals based on the plurality of pressure measurement signals and based on a position of a driver in the vehicle;
aggregating the optimum PPG waveform signals into a PPG measurement signal;
outputting the PPG measurement signal to determine a state of the driver; and
controlling at least one vehicle system of the vehicle based on the driver state of the driver.

US Pat. No. 10,213,161

IMPLANTABLE DEVICE WITH AN OXYGEN SENSOR AND A METHOD OF OPERATING AN IMPLANTABLE DEVICE WITH AN OXYGEN SENSOR

1. A device configured to be inserted into a bodily tissue or in blood of a human or animal body, comprising:at least one permanently implantable sensor unit that detects a signal that represents an oxygen content along a measurement path,
wherein said at least one permanently implantable sensor unit comprises a transmitter and a receiver;
a reflector provided on the device, wherein said reflector is arranged in the measurement path between the transmitter and the receiver of the at least one permanently implantable sensor unit to reflect the signal; and,
a fixation unit, wherein the reflector is arranged on or in said fixation unit configured to permanently fix the device to or in the bodily tissue.

US Pat. No. 10,213,160

ENDOTRACHEAL TUBE APPARATUS

Medtronic Xomed, Inc., J...

1. A method, comprising:providing an endotracheal tube having an exterior surface and at least four conductive ink electrodes on the exterior surface, wherein the at least four conductive ink electrodes include at least two stimulating electrodes and at least two monitoring electrodes;
stimulating tissue of a patient with the stimulating electrodes; and
monitoring at least one nerve of the patient using the monitoring electrodes during the stimulation.

US Pat. No. 10,213,159

BODY-WORN VITAL SIGN MONITOR

SOTERA WIRELESS, INC., S...

1. A method for monitoring a patient, comprising the following steps:(a) associating a first patient monitor comprising a first motion sensor and a first transceiver with a patient;
(b) transmitting a first set of vital sign information measured from the patient from the first patient monitor to a remote data server and storing the first set of vital sign information as being associated with the patient in a computer memory on the remote data server;
(c) contacting the first patient monitor with a second patient monitor comprising a second motion sensor and a second transceiver, the contacting causing the first motion sensor to generate a first motion signal, and the second motion sensor to generate a second motion signal;
(d) transmitting the first and second motion signals to the remote data server and processing the first and second motion signals at the remote data server to determine that the first patient monitor is to be replaced by the second patient monitor;
(e) upon determining that the first patient monitor is to be replaced by the second patient monitor, associating the second patient monitor with the patient and rendering the first patient monitor inactive relative to the patient; and
(f) transmitting a second set of vital sign information measured from the patient from the second patient monitor to the remote data server and storing the second set of vital sign information as being associated with the patient in the computer memory on the remote data server.

US Pat. No. 10,213,158

SYSTEMS AND METHODS FOR BIOMETRIC SENSING WITH SENSOR FUSION

4iiii Innovations Inc., ...

1. A system for biometric sensing using sensor fusion, comprising:a first pod configured to be positioned on a first body part of a user, the first pod including:
a first sensor configured to couple with the first body part to sense movement characteristics of the user; and
a first transceiver configured to transmit the movement characteristics; and
a second pod configured to be positioned on a second body part of the user different from the first body part, the second pod including:
a second sensor configured to couple with the second body part to sense biometric characteristics of the user;
a second transceiver configured to receive the movement characteristics from the first pod;
a processor; and
a memory storing machine-readable instructions that, when executed by the processor, control the processor to implement an algorithm to correct for motion artifacts within the biometric characteristics based upon an activity of the user determined from the movement characteristics.

US Pat. No. 10,213,157

ACTIVE UNIPOLAR DRY ELECTRODE OPEN EAR WIRELESS HEADSET AND BRAIN COMPUTER INTERFACE

BOSE CORPORATION, Framin...

1. A wearable audio product for obtaining biologically-relevant information associated with a user comprising:a first electrode placed over the user's auditory cortex on a first side of the user's body;
a second electrode placed on the first side of the user's body;
a first reference electrode placed on the first side of the user's body;
a third electrode placed over the user's auditory cortex on a second side of the user's body;
a fourth electrode placed on the second side of the user's body; and
a second reference electrode placed on the second side of the user's body,
a processor coupled to the first, second, first reference, third, fourth, and second reference electrodes, the processor configured to take one or more actions based on signals received from the first, second, first reference, third, fourth, and second reference electrodes,
wherein taking the one or more actions comprises:
combining signals from first side movement artifacts, the user's brain signals detected by the first and second electrodes, and the first reference electrode to generate a combined first side signal;
combining signals from second side movement artifacts, the user's brain signals detected by the third and fourth electrodes, and the second reference electrode to generate a combined second side signal;
comparing the combined first side signal and the combined second side signal to output a difference for the first side and a difference for the second side;
applying a first closed feedback loop for signals received from the first side of the body including the difference for the first side signal,
applying a second closed feedback loop for signals received from the second side of the body including the difference for the second side signal, and
removing noise from the received signals based on the first and second closed feedback loops, wherein removing the noise comprises cross-correlating the signals received from the first side of the body with the signals received from the second side of the body; and
an electroacoustic transducer coupled to the processor.

US Pat. No. 10,213,156

HEADSET APPARATUS FOR DETECTING MULTI-BIOSIGNAL

SoSo Co. Ltd., Daegu (KR...

1. A headset apparatus for detecting a multi bio-signal, comprising:a headset body configured to be mounted on a head of a user;
a plurality of electrodes which are exposed on an outer surface of the headset body so as to be in contact with a forehead of the user when the headset body is mounted on the head of the user;
a brainwave detection sensor embedded in the headset body, and configured to detect a brainwave signal based on a signal detected by the plurality of electrodes;
a heartbeat detection sensor extending from the headset body through a signal cable, and configured to be mounted on an ear of the user to detect a heartbeat signal; and
a headset controller configured to
analyze frequencies of the brainwave signal to extract an alpha wave and a beta wave,
calculate a brainwave stress index based on the alpha wave and the beta wave,
calculate a heartbeat stress index based on a variation of an R-peak interval of the heartbeat signal,
respectively apply predetermined weight factors to the brainwave stress index and the heartbeat stress index to generate a weighted brainwave stress index and a weighted heartbeat stress index, and
add the weighted brainwave stress index and the weighted heartbeat stress index to calculate a complex stress index.

US Pat. No. 10,213,154

STRAIN SENSOR DEVICE WITH A BIOLOGICAL SUBSTRATE AND METHOD OF MANUFACTURING THEREOF

COLORADO STATE UNIVERSITY...

1. A strain sensor device implantable in a biological subject, the strain sensor device comprising:a biological substrate composed of a bone graft;
a first dielectric layer composed of dielectric material disposed over the biological substrate;
a bonding interface, composed of an underlayer and a first interface layer, disposed between the biological substrate and the first dielectric layer, the underlayer being disposed on the biological substrate and the first interface layer being disposed on the underlayer;
a first conductive layer having a pattern disposed over the first dielectric material; and
a second dielectric layer;
a second conductive layer,
wherein the second dielectric layer and the second conductive layer are disposed between the first interlace layer and the first dielectric layer; and
a strain sensing circuit, composed of the first dielectric layer, the first conductive layer, the second dielectric layer, and the second conductive layer, that functions as a strain gauge.

US Pat. No. 10,213,153

WEARABLE PAIN MONITOR USING ACCELEROMETRY

Koninklijke Philips N.V.,...

1. A device for monitoring pain of a user, comprising:a receiving unit configured to receive an accelerometer signal from an accelerometer sensor configured to be worn in use by the user, wherein the accelerometer signal from the accelerometer sensor comprises components of a pulse signal and components of a respiration signal; and
a processing unit which is configured to:
derive the instantaneous pulse signal and the respiration signal from the accelerometer signal;
adapt the pulse signal based on the respiration signal in order to obtain a corrected pulse signal; and
derive a pain descriptor based on the corrected pulse signal.

US Pat. No. 10,213,152

SYSTEM AND METHOD FOR REAL-TIME MEASUREMENT OF SLEEP QUALITY

THE BOARD OF REGENTS OF T...

1. A method for real time monitoring and measurement of sleep quality of a subject comprising:receiving, at a smartphone, a sensor signal corresponding to an electrocardiogram (ECG) from a subject and context information from one or more contextual sensors;
analyzing, at the smartphone or a server, information contained within the sensor signal using signal processing and artificial intelligence, the analyzing comprising:
segmenting the sensor signal corresponding to the ECG into signal segments of a specified epoch; and
for each signal segment:
detecting a set of characteristic points from the signal segment;
extracting a feature set of elements from the signal segment using the set of characteristic points, time-based parameters, and frequency-based parameters, wherein the time-based parameters comprise ECG derived respiration (EDR) time series and RR time series, and the frequency-based parameters comprise EDR time series and RR time series; and
classifying the signal segment as containing an apnea event or not containing the apnea event according to the extracted feature set, wherein classifying the signal segment comprises training a classifier with both self-learning algorithms and machine learning algorithms, the training including using the context information obtained automatically by the one or more contextual sensors and including optimizing the classifier for the subject through continued use by the subject of a device providing the sensor signal such that accuracy increases for classifying apnea events occurring for the subject; and
outputting, via the smartphone, a sleep quality index of the subject based on at least one signal segment that has been classified as containing the apnea event or not containing the apnea event, wherein the sleep quality index is a total number of apnea events over an amount of sleep time.

US Pat. No. 10,213,150

EARLY ALLERGY DETECTION, NOTIFICATION AND MANAGEMENT SYSTEMS AND METHODS

1. An early allergy detection, notification and management system comprising a first watch, said first watch in turn comprising:an early allergy detection system comprising at least one ambient sensor, at least one physical activity sensor, and at least one physiological sensor, said at least one physiological sensor is placed on an inner surface of said first watch and configured to detect a symptom of an allergic reaction,
an early allergy notification system configured to activate a local alarm or a wireless alarm upon detection of an onset of an allergic reaction,
an early allergy management system comprising a subject locator and a medication storage compartment, and
a first controller operably connected with said early allergy detection system, said early allergy notification system, and said early allergy management system, said first controller is further configured to detect an onset of an allergic reaction using data from said at least one ambient sensor, said at least one physical activity sensor, and said at least one physiological sensor.

US Pat. No. 10,213,149

SYSTEMS AND METHODS FOR ASSESSING HUMAN COGNITION, INCLUDING A QUANTITATIVE APPROACH TO ASSESSING EXECUTIVE FUNCTION

Medical Care Corporation,...

1. A computer-implemented method comprising:receiving data comprising (i) a person's responses regarding judgments of semantic similarities between items selected from a group of items falling into a same categorical level, and (ii) delayed free recall responses by the person of items presented for the judgments of semantic similarities, wherein the responses regarding the judgments of semantic similarities are responses to triadic comparisons;
processing the data to determine a measure of distance within a generated representation of the person's responses regarding the judgments of semantic similarities, wherein the processing comprises transforming the responses regarding the judgments of semantic similarities into a spatial representation and applying a spatial randomness metric to the spatial representation, and wherein the spatial randomness metric comprises a ratio of observed mean nearest neighbor distance for the responses represented in the spatial representation to a mean nearest neighbor distance expected for random responses within the spatial representation; and
generating a quantitative score of executive function for the person based at least in part on the determined measure of distance within the generated representation regarding the judgments of semantic similarities, and providing the quantitative score of executive function, to a user device of a human cognition assessment system comprising one or more computers, for use by a clinician in assessing cognitive impairment of the person, wherein the generating comprises:
determining the measure of distance within the generated representation using distance values calculated for the responses to the triadic comparisons within the generated representation;
determining an additional measure for the delayed free recall responses using the calculated distance values for the responses to the triadic comparisons; and
comparing the measure of distance with the additional measure to assess an interaction between judgment and associative memory when preparing the score; and
wherein the generating comprises using (i) measured degrees of spatial randomness for responses of one or more groups of people to judgments of semantic similarities and (ii) delayed free recall responses by the one or more groups of people of items presented for judgments of semantic similarities.

US Pat. No. 10,213,148

SPINAL CORD STIMULATION GUIDANCE SYSTEM AND METHOD OF USE

Pacesetter, Inc., Sylmar...

1. A method for modeling patient-specific spinal cord stimulation (SCS), the method comprising:acquiring impedance and evoked compound action potential (ECAP) signals with a neuro-stimulation system coupled to a lead positioned proximate to a spinal cord (SC), wherein the lead includes at least one electrode;
utilizing a processor, when executing programmed instructions, to perform the following operations:
determining a patient-specific anatomical model based on the impendence and ECAP signals;
transforming a dorsal column (DC) map template based on a DC boundary of the patient-specific anatomical model; and
mapping the transformed DC map template to the patient-specific anatomical model.

US Pat. No. 10,213,147

METHOD AND SYSTEMS FOR DETECTING FROM BIOMETRICS THAT PERSON SITTING IN SEAT OF VEHICLE REQUIRES MEDICAL ATTENTION AND FOR PROVIDING MEDICAL ATTENTION TO THE PERSON

Lear Corporation, Southf...

1. A method for a vehicle, comprising:establishing a medical practitioner network having as a subscriber to the medical practitioner network a person that is sitting in a seat of the vehicle and having as providers of the medical practitioner network a plurality of medical practitioners;
detecting, from one or more sensors in the seat of the vehicle, biometrics of the person;
determining from the biometrics of the person, by a vehicle controller in communication with the one or more sensors, whether the person requires medical attention; and
in response to the vehicle controller determining from the biometrics of the person that the person requires medical attention, broadcasting, from a V2X transceiver of the vehicle, a request for assistance for the person to medical practitioners of the medical practitioner network who are near a location of vehicle during the broadcasting.

US Pat. No. 10,213,145

CONTEXT-AWARE POST TRAUMATIC STRESS DISORDER MONITORING AND INTERVENTION

Cerner Innovation, Inc., ...

20. A computerized system comprising:one or more processors; and
computer memory storing computer-usable instructions that, when used by the one or more processors, cause the one or more processors to:
generate a heart-rate variability (HRV) time-series, wherein in the HRV time-series includes a serial sequence of cardiac signals comprising a time-based sequence of RR intervals and at least one HRV parameter derived from the HRV of a patient;
append the HRV time-series to a plurality of corresponding previously acquired serial sequences of cardiac signals and corresponding previously generated HRV parameters thereby forming a current HRV time-series;
derive at least one fractal property for the current HRV time-series, wherein the fractal property includes at least one of the Hurst exponent for the time-series or the entropy of the time-series;
associate a current PTSD screen for the patient with the HRV time-series;
determine that the associated PTSD screen is complete, wherein a complete PTSD assessment includes a PTSD screen score;
determine a context for the patient based on the PTSD screen score based on a set of reference PTSD screens having associated reference PTSD screen scores;
determine, based on the context determination, a set of normative HRV value ranges, wherein the normative HRV value ranges include at least one HRV parameter and one fractal property corresponding to the at least one parameter associated with the HRV of the patient and the derived fractal property for the current time-series; and
determine, for each normative HRV value, whether the patient's corresponding HRV value is outside the retrieved normative HRV value range; and
based on the determining, generate a PTSD monitoring assessment for notification to a case manager.

US Pat. No. 10,213,144

NANOPATTERNED BIOSENSOR ELECTRODE FOR ENHANCED SENSOR SIGNAL AND SENSITIVITY

International Business Ma...

1. An electrode structure comprising:an electrode base having non-random topography located on one surface of said electrode base, wherein said electrode base and said non-random topography are of uniform construction and uniform composition; and
a biological functionalization material located directly on a surface of said non-random topography, wherein said uniform composition of said electrode base and said non-random topography comprise an amorphous conductive material.

US Pat. No. 10,213,143

ENCLOSED DESORPTION ELECTROSPRAY IONIZATION PROBES AND METHOD OF USE THEREOF

Purdue Research Foundatio...

1. A method for analyzing a tissue section, the method comprising:providing a tissue section;
directing a liquid droplet spray discharge from a desorption electrospray ionization probe onto the tissue section, wherein the liquid droplet spray discharge from the desorption electrospray ionization probe desorbs and ionizes an analyte from the tissue section in a manner that preserves the tissue section for further analysis;
transferring the ions of the analyte to a mass spectrometer; and
analyzing the ions of the analyte in the mass spectrometer, thereby analyzing the tissue section.

US Pat. No. 10,213,141

SYSTEMS, DEVICES, AND METHODS FOR ENERGY EFFICIENT ELECTRICAL DEVICE ACTIVATION

ABBOTT DIABETES CARE INC....

1. A method of preparing a sensor control device for continuous analyte monitoring for a user, comprising:removing a cover from an applicator housing the sensor control device; and
exposing an optical activation sensor to optical light such that the optical activation sensor initiates activation of a processor in the sensor control device,
wherein the optical activation sensor is housed within the sensor control device adjacent to a transparent or semi-transparent window structure in a housing of the sensor device, and
wherein the sensor control device comprises a surface covered with adhesive for coupling the sensor control device to the user, a portion of the surface being free of adhesive to permit passage of optical light through the window structure.

US Pat. No. 10,213,140

OPHTHALMIC LENS WITH A MICROFLUIDIC SYSTEM

1. An ophthalmic device, including an ocular fluid analysis system, comprising:an ophthalmic device body;
a media insert encapsulated within the ophthalmic device body, wherein the media insert comprises a first annular insert piece attached to and sealed together with a second annular insert piece to form an annular shaped insert having an annular cavity between the first annular insert piece and the second annular insert piece,
an energy source within the cavity and configured to provide energy to the ocular fluid analysis system,
a microfluidic analytical system within the cavity and in electrical communication with the energy source, wherein the microfluidic analytical system comprises a micro-channel for receiving and transporting fluid and is configured operatively to measure one or more properties of an ocular fluid sample flowed through the micro-channel; and,
a processor within the cavity and configured to execute a program including preprogrammed threshold values for one or more of the ocular fluid properties and to output a signal when the received measurements are outside the corresponding preprogrammed threshold values;
the media insert further comprises an opening into the cavity that exposes the micro-channel of the microfluidic analytical system to a user's ocular fluid that is external to the ophthalmic device.

US Pat. No. 10,213,139

SYSTEMS, DEVICES, AND METHODS FOR ASSEMBLING AN APPLICATOR AND SENSOR CONTROL DEVICE

ABBOTT DIABETES CARE INC....

1. A method of assembling an in vivo analyte sensor control device, comprising:orienting an applicator with respect to a container,
wherein the applicator comprises a housing, a sheath, and an electronics housing of the sensor control device, the sheath being slidably coupled with the housing and comprising (a) a deflectable lock arm in contact with the housing such that the housing is prevented from moving distally with respect to the sheath and (b) a deflectable positioning arm having a detent releasably positioned within a first groove of the housing, and
wherein the container holds a sensor module and a sharp module and comprises a platform having a sheath unlock abutment located thereon;
distally advancing the applicator into the container such that the sheath unlock abutment contacts a sloped surface of the deflectable lock arm and causes the lock arm to deflect from contact with the housing, whereby the sheath is unlocked from the housing and releasably maintained in position with respect to the housing by the deflectable positioning arm;
distally advancing the housing against the platform to move the platform into the container until contact of the container against the sheath causes the sheath to move with respect to the housing such that the detent of the deflectable positioning arm moves from the first groove to a releasable position within a second groove and the deflectable lock arm is held in an unlocked position.

US Pat. No. 10,213,138

USER INTERFACE AND METHOD TO DISCOVER HEARING SENSITIVITY OF USER ON SMART PHONE

BITWAVE PTE LTD., Singap...

1. A system, comprising:a processor; and
a memory communicatively coupled to the processor, the memory having stored therein computer-executable instructions, comprising:
a tone generation component configured to output a tone, corresponding to a currently selected frequency band, to a currently selected ear at a signal level of a first predetermined value;
a user interface component configured to:
instruct the tone generation component to adjust the signal level of the tone in a first direction at a granularity level until receipt of a first input, wherein the first direction is one of increasing or decreasing, wherein the first input indicates hearing of the tone by the currently selected ear based on the first direction being increasing, or wherein the first input indicates not hearing of the tone by the currently selected ear based on the first direction being decreasing,
receive the first input,
instruct the tone generation component to adjust the signal level of the tone in a second direction at a finer granularity level than the granularity level in the first direction until receipt of a second input, wherein the second direction is opposite the first direction, and wherein the second input indicates hearing of the tone by the currently selected ear based on the second direction being increasing, or wherein the second input indicates not hearing of the tone by the currently selected ear based on the second direction being decreasing,
receive the second input, and
repeat, until a predetermined number of changes in direction has occurred, at least one of the instruct the tone generation component to adjust the signal level of the tone in the first direction and receive the first input or the instruct the tone generation component to adjust the signal level of the tone in the second direction and receive the second input, wherein at each change in direction of the predetermined number of changes, the granularity level is made finer than a preceding granularity level associated with an immediately preceding direction by the user interface component; and
a sensitivity results component configured to record a current signal level of the tone for the currently selected frequency band and the currently selected ear in a hearing sensitivity testing results record.

US Pat. No. 10,213,136

METHOD FOR SENSOR ORIENTATION INVARIANT GAIT ANALYSIS USING GYROSCOPES

BAE Systems Information a...

1. A method for invariant gait analysis using gyroscope data comprising:obtaining, from at least one gyroscope, at least one pair of raw data measurements;
obtaining, from said at least one pair of raw data measurements, at least two 3D rotation vectors;
obtaining, from said at least one gyroscope, at least a second pair of raw data measurements;
obtaining, from said at least a second pair of raw data measurements, at least a second set of two 3D rotation vectors;
determining, from said at least two 3D rotation vectors and said at least a second set of two 3D rotation vectors, Gait Dynamics Images (GDIs);
determining sequences by matching features of said GDIs to sequences; and
outputting identification and or classification of features from said determined sequences,
whereby said pairs of raw measurements are used to factor out orientation, providing a motion representation which is both invariant to sensor orientation changes and highly discriminative, thereby providing high-performance gait analysis.

US Pat. No. 10,213,135

EQUESTRIAN MONITORING AND FEEDBACK DEVICE

1. An equestrian monitoring device comprising a load measuring bracket having a means for attachment to a saddle and having an attachment hook for receiving a stirrup leather and said load measuring bracket measuring at least one parameter of load data, and further comprising a power supply and processing circuitry to process load data signals from the load measuring bracket and generate at least one feedback signal.

US Pat. No. 10,213,133

MODELING OF A MAGNETIC FIELD

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:generating a magnetic field in a region from a first magnetic field radiator located at a first position and a second magnetic field radiator located at a second position;
delineating within the region a volume having a multiplicity of vertices;
measuring respective values of the magnetic field at the multiplicity of vertices;
in response to the respective values and in response to displacements of the multiplicity of vertices from an origin of a frame of reference defined by the first position and the second position, assigning respective first dipole moments to the first magnetic field radiator and assigning respective second dipole moments to the second magnetic field radiator; and
calculating a value of the magnetic field within the volume in terms of the first dipole moments and the second dipole moments.

US Pat. No. 10,213,131

METHOD OF GENERATING MAGNETIC RESONANCE IMAGE AND MEDICAL IMAGING APPARATUS USING THE METHOD

SAMSUNG ELECTRONICS CO., ...

1. A medical imaging apparatus comprising:a signal controller configured to determine flip angles respectively corresponding to radio frequency (RF) refocusing pulses included in a fast spin-echo (FSE) pulse sequence, based on a pseudo-steady state model of a flip angle schedule;
an RF transmitter configured to apply an RF excitation pulse to an object, and apply the RF refocusing pulses to the object based on the determined flip angles; and
an image processor configured to generate a magnetic resonance (MR) image based on an MR signal that is received from the object.

US Pat. No. 10,213,130

COMPRESSABLE CATHETER TIP WITH IMAGE-BASED FORCE SENSING

Siemens Healthcare GmbH, ...

1. A catheter comprisinga compressible catheter tip that includes a moveable distal tip slidably connected to a fixed proximal tip and a plurality of markers,
wherein at least one of said plurality of markers is positioned on the moveable distal tip and at least one of said plurality of markers is positioned on the fixed proximal tip,
wherein the plurality of markers are adapted to permit an external image guidance system to track the markers, to obtain positional information of the markers, and to estimate contact force of the tip from the positional information.

US Pat. No. 10,213,129

DEVICES, SYSTEMS, AND METHODS TO OBTAIN CONDUCTANCE AND TEMPERATURE DATA

3DT Holdings, LLC, San D...

1. A method to obtain conductance data within a luminal organ, the method comprising the steps of:operating a detection device having an elongate body with a plurality of electrodes and a thermistor disposed thereon, wherein at least one of the electrodes is located distal to the thermistor, and wherein the elongate body of the detection device is at least partially positioned within the luminal organ to detect a temperature change using the thermistor from a first temperature to a temperature indicative of an injection of a bolus of a solution having a known conductivity;
obtaining multiple conductance measurements using at least one of the plurality of the electrodes located along the elongate body of the detection device prior to dilution of the bolus until a threshold temperature is reached;
calculating a dimension of the luminal organ based in part upon at least one conductance measurement of the multiple conductance measurements; and
selecting an appropriately-sized stent based upon the calculated dimension.

US Pat. No. 10,213,128

UWB MICROWAVE IMAGING SYSTEM WITH A NOVEL CALIBRATION APPROACH FOR BREAST CANCER DETECTION

JointVue LLC, Knoxville,...

1. A medical imaging device comprising:a tissue support having a size and shape to receive a tissue;
a plurality of transducers operably coupled to the tissue support, each of the plurality of transducers having a transmitting antenna and a receiving antenna, the transmitting antenna operable in a frequency range of 2 GHz to 8 GHz and the receiving antenna operable in a frequency range of 2 GHz to 8 GHz, wherein a select one of the plurality of transducers transmits a first signal and receives a first total signal and an adjacent one of the plurality of transducers transmits a second signal and receives a second total signal;
a controller configured to calculate a calibrated signal by subtracting the second total signal from the first total signal.

US Pat. No. 10,213,127

DETECTOR ARRAYS WITH ELECTRONICALLY ADJUSTABLE DETECTOR POSITIONS

Raytheon Company, Waltha...

1. A method for improving image resolution, the method comprising:a) receiving, at a detector array, electromagnetic (EM) radiation from a target object, the detector array comprising one or more detectors, each detector organized into a plurality of segments, each segment comprising one or more rows of the detector substantially perpendicular to a designed scan axis, each segment comprising one or more columns of detecting components substantially parallel to the designed scan axis, each column comprising one or more sub-columns; the detector array moving in a relative scan direction relative to the target object; a readout circuit being operatively connected to the detector array, the readout circuit comprising a number of detector boundary selection components, each one of the number of detector boundary selection components configured to select or adjust a predetermined detector sub-column boundary or an adjustable sub-column boundary;
b) performing the following for each segment of the detector array:
if electromagnetic (EM) radiation is received from the target object in a first detection, use detector boundaries in a conventional configuration;
otherwise, activate selected ones of the number of detector boundary selection components;
and
c) obtaining, from said each segment of the detector array, a plurality of signals;
d) repeat steps (a) through (c) a predetermined number of times; the selected ones of the number of detector boundary selection components being selected to produce a predetermined number of overlapping pluralities of signals; the selected ones of the number of detector boundary selection components being selected according to an image resolution improvement prescription.

US Pat. No. 10,213,126

DETECTOR ARRAYS WITH ELECTRONICALLY ADJUSTABLE DETECTOR POSITIONS

Raytheon Company, Waltha...

1. A method for correcting misalignment, the method comprising:receiving, at a detector array, electromagnetic (EM) radiation from a target object, the detector array comprising one or more detectors, each detector organized into a plurality of segments, each segment comprising one or more rows of the detector substantially perpendicular to a designed scan axis, each segment comprising one or more columns of detecting components substantially parallel to the designed scan axis, each column comprising one or more sub-columns; the detector array moving in a relative scan direction relative to the target object; a readout circuit being operatively connected to the detector array, the readout circuit comprising a number of detector boundary selection components, each one of the number of detector boundary selection components configured to select or adjust a detector boundary at one sub-column boundary or adjustable sub-column boundary; and
performing the following for each segment of the detector array:
if there is misalignment at a segment, activating selected ones of the number of detector boundary selection components; the selected ones being selected to correct the misalignment by moving detector boundaries in order to correct misalignment;
otherwise, using detector boundaries in a conventional configuration; and
obtaining, from said each segment of the detector array, a plurality of signals.

US Pat. No. 10,213,125

ATRIAL ARRHYTHMIA EPISODE DETECTION IN A CARDIAC MEDICAL DEVICE

Medtronic, Inc., Minneap...

1. A method of detecting an atrial fibrillation (AF) event in a medical device, comprising:sensing a cardiac signal;
identifying a plurality of R-waves in the cardiac signal;
determining a plurality of RR-intervals based on the plurality of identified R-waves in the sensed cardiac signal;
detecting the AF event based on at least the plurality of determined RR-intervals;
iteratively sensing a predetermined number of P-waves in response to detecting the AF event;
determining one or more P-wave parameters associated with each of the iteratively sensed predetermined number of P-waves; and
confirming the AF event based on the P-wave parameters of the iteratively sensed predetermined number of P-waves.

US Pat. No. 10,213,124

ELECTROCARDIOGRAM PACKAGE

ZOLL Medical Corporation,...

1. A device comprising:a housing having a dispensing hole that extends through a side wall of the housing;
at least one core enclosed within the housing and disposed along at least a portion of a length of the housing, the at least one core configured to rotate relative to the housing;
a plurality of electrocardiogram (ECG) cables enclosed within the housing and wound around the at least one core enclosed within the housing, each ECG cable of the plurality of ECG cables having a distal end and having a proximal end comprising an electrode pad mechanically coupled to and in contact with the at least one core; and
an electrical connector, accessible at the dispensing hole and attached, at the distal end of each ECG cable, to all of the plurality of ECG cables wound around the at least one core enclosed within the housing and configured to cause the plurality of ECG cables to unwind from the at least one core and emerge from the housing through the dispensing hole in response to the electrical connector being pulled in a direction away from the housing, wherein the electrical connector is configured to connect to a port of a mobile device.

US Pat. No. 10,213,123

CARDIOVASCULAR MONITORING DEVICE

MOCACARE, CORP., Palo Al...

1. A method of measuring a blood pressure value of a user, the method comprising:placing a first thumb of the user in an indented portion near one end of a top surface of a handheld physiological measuring apparatus, wherein the indented portion is formed from an electroconductive material that acts as a first electrode, and the indented portion includes at least one sensor located inside the first electrode at a bottom of the indented portion;
placing a second thumb of the user on the top surface of the handheld physiological measuring apparatus, away from the indented portion, wherein the top surface is made of the electroconductive material that acts as a second electrode of the handheld physiological monitoring device; wherein the first electrode is electrically isolated from the second electrode by an insulating spacer;
measuring an electrocardiogram signal using an electrocardiogram circuit unit including the first electrode and the second electrode;
measuring a dual pulse wave signal using a pulse circuit unit of the handheld physiological measuring apparatus, wherein the pulse circuit unit is positioned at a same location on the handheld physiological measuring apparatus as the second electrode;
calculating a pulse transit time using the electrocardiogram signal and the dual pulse wave signal;
calculating a pulse wave velocity using the electrocardiogram signal and the dual pulse wave signal;
calculating the blood pressure value using the calculated pulse transit time and the calculated pulse wave velocity; and
outputting the calculated blood pressure value to the user.

US Pat. No. 10,213,122

SYSTEMS AND METHODS FOR PEDAL REVASCULARIZATION ASSESSMENT

Nanyang Technological Uni...

1. A system for assessment of peripheral blood flow characteristics in deep tissue, the system comprising:a support structure configured to be positioned onto an external body part of a patient; at least one diffuse optical flow (DOF) sensor carried by the support structure and configured to be positioned in optical communication with a skin surface of the patient, the at least one DOF sensor comprising a return optical conduit, and at least one input optical fiber comprising an end configured to be positioned proximate the skin surface of the patient, the at least one input optical fiber in optical communication with a coherent laser light source;
a photodetector operably connected to the at least one DOF sensor;
a processor configured to analyze data from the at least one DOF sensor to determine blood flow characteristics at a location near the at least one DOF sensor when the support structure is positioned onto the external body part of the patient, the processor configured to determine blood flow characteristics in blood vessels of the patient by determining a spatial speckle contrast ratio (Ks) or a temporal speckle contrast ratio (Kt) and determining 1/Ks2 or 1/Kt2 from intensity fluctuations, and correlating 1/Ks2 or 1/Kt2 values with blood flow; and
a display configured to provide feedback indicative of the blood flow characteristics determined by the processor,
wherein the at least one DOF sensor is configured to capture light scattered diffusively into tissue and transmitted at a depth of penetration of between 5 mm and 50 mm.

US Pat. No. 10,213,121

PHYSIOLOGICAL MONITORING METHODS AND SYSTEMS UTILIZING DISTRIBUTED ALGORITHMS

COVIDIEN LP, Mansfield, ...

1. A physiological monitoring system, comprising:a sensor configured to:
store a first executable code segment; and
generate a photoplethysmographic (PPG) signal; and
a physiological monitor comprising:
a port communicatively coupled to the sensor, the port being configured to:
receive the first executable code segment from the sensor; and
receive the PPG signal from the sensor;
non-transitory memory configured to store a second executable code segment; and
at least one processor configured to:
execute the first executable code segment and the second executable code segment upon receiving the first executable code segment from the sensor to determine at least one physiological parameter of a subject based on the PPG signal; and
wherein the second executable code segment is operable without the first executable code segment; and
wherein the second executable code segment is maintained in the non-transitory memory of the physiological monitor subsequent to disconnection of the sensor from the port.

US Pat. No. 10,213,120

SYSTEMS, APPARATUSES AND METHODS FOR SENSING FETAL ACTIVITY

Nuvo Group Ltd., Ramat G...

1. A computer-implemented method, comprising:receiving, by at least one computer processor executing specific programmable instructions configured for the method, a plurality of Phonocardiogram (PCG) signals data inputs from a plurality of acoustic sensors;
transforming, by the at least one computer processor, utilizing an Independent-Component-Analysis (ICA), at least one first subset of the PCG signals data inputs to form a plurality of ICA transforms;
wavelet denoising, by the at least one computer processor, at least one second subset of the PCG signals data inputs to form a plurality of denoised PCG outputs;
transforming, by the at least one computer processor, utilizing the ICA, the plurality of denoised PCG outputs to form a plurality of denoised ICA transforms;
compiling, by the at least one computer processor, a plurality of detection heartbeat (DH) inputs, wherein the plurality of DH inputs comprises:
i) the plurality of ICA transforms, and
ii) the plurality of denoised ICA transforms;
detecting, by the at least one computer processor, locations of potential heartbeats in each of the DH inputs;
calculating, by the at least one computer processor, a plurality of confidence scores, each of the confidence scores corresponding to one of the potential heartbeats, wherein each of the confidence scores describes a probability that the corresponding one of the potential heartbeats represents an actual heartbeat and not a noise;
selecting, by the at least one computer processor, the ones of the DH inputs that include at least one actual heartbeat;
dividing, by the at least one computer processor, the selected DH inputs into at least two groups:
i) a first group of selected DH inputs containing potential fetal heartbeats, and
ii) a second group of selected DH inputs containing potential maternal heartbeats;
selecting, by the at least one computer processor, from the first group of selected DH inputs, at least one of the plurality of selected DH inputs that contains at least one actual fetal heartbeat, based on the at least one of the plurality of confidence scores corresponding to the at least one of the actual heartbeats included in the at least one of the plurality of selected DH inputs;
selecting, by the at least one computer processor, from the second group of selected DH inputs, at least one of the plurality of selected DH inputs that contains at least one actual maternal heartbeat, based on the at least one of the plurality of confidence scores corresponding to the at least one of the actual heartbeats included in the at least one of the plurality of selected DH inputs; and
outputting at least one visual indication corresponding to at least one of (a) the at least one actual maternal heartbeat and (b) the at least one actual fetal heartbeat.