US Pat. No. 11,065,228

ANTIFUNGAL AGENTS

F2G Limited, Manchester ...


1. A method of preventing fungal disease in a subject, which method comprises administering to said subject an effective amount of:2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)phenyl)-2-oxoacetamide, or a pharmaceutically acceptable salt thereof,
wherein the fungal disease is caused by an Aspergillus species.

US Pat. No. 11,065,226

COMBINATION COMPRISING EP4 ANTAGONIST AND IMMUNE CHECKPOINT INHIBITOR

ONO PHARMACEUTICAL CO., L...


1. A method for treating cancer comprising administering effective amounts of the compound represented by formula (I), a salt thereof, a solvate thereof, or an N-oxide thereof and an immune checkpoint inhibitor to a mammal in need thereof, wherein formula (I) represents



wherein R1 represents COOR8, tetrazole, SO3H, SO2NH2, SO2NHR8?1, CONHSO2R8?1, SO2NHCOR8?1, or hydroxamic acid,
wherein R8 represents a hydrogen atom, C1-4 alkyl, or benzyl, and
R8?1 represents C1-4 alkyl, C1-4 haloalkyl, a C3-10 carbon ring, or a three- to ten-membered heterocyclic ring, wherein the C3-10 carbon ring and the three- to ten-membered heterocyclic ring each may be substituted with C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, —O(C1-4 haloalkyl), C1-4 alkylthio, —S(C1-4 haloalkyl), halogen, or nitrile,
L1 represents C1-5 alkylene, C2-5 alkenylene, or C2-5 alkynylene,
R2 represents halogen, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C2-4 alkenyl, C2-4 alkynyl, —O(C1-4 haloalkyl), —S(C1-4 haloalkyl), —C(O)(C1-4 alkyl), —SO2(C1-4 alkyl), —CONH(C1-4 alkyl), —CON(C1-4 alkyl)2, —NHC(O)(C1-4 alkyl), —N(C 1-4 alkyl)C(O)(C1-4 alkyl), —NHSO2(C1-4 alkyl), —N(C 1-4 alkyl)SO2(C 1-4 alkyl), —SO2NH(C 1-4 alkyl), —SO2N(C 1-4 alkyl)2, —NR17R17, nitro, nitrile, a hydroxyl group, aldehyde, or carboxyl, wherein the C1-4 alkyl groups each may be substituted with halogen, and
the (C1-4 alkyl)2 in R2 represents two independent C1-4 alkyl groups which may be the same or different,
X1 represents CR6, wherein R6 represents a hydrogen atom,
X2 represents CR7, wherein R7 represents halogen or nitrile,
L2 represents —NHCO—, —CONH—,
R3 represents C1-4 alkyl or halogen,
R4 represents halogen, C1-4 alkyl, or C1-4 haloalkyl,
X3 represents methylene or an oxygen atom,
the ring represents a benzene,

represents a single bond or a double bond,
R5 represents halogen, C1-4 alkyl, carboxyl, nitrile, —CONHR11, —C(O)R12, —OR14, —S(O)tR15, —CH2R16, —NR17R17, NHCOR11, a C4-10 carbon ring, or a four- to ten-membered heterocyclic ring, wherein the C4-10 carbon ring or the four- to ten-membered heterocyclic ring may be substituted with one to three R18, wherein, when a plurality of R18 exists, the plurality of R18 each independently may be the same or different,
R11 represents C1-6 alkyl, C3-6 cycloalkyl, phenyl, or a four- to six-membered heterocyclic ring and may be substituted with one to three R13, wherein, when a plurality of R13 exists, the plurality of R13 each independently may be the same or different, and
R13 represents halogen, C1-6 alkyl, C3-6 cycloalkyl, C1-4 alkoxy, a hydroxyl group, —NR20R21, benzene, or a four- to six-membered heterocyclic ring,
wherein R20 and R21 each independently represent a hydrogen atom or C1-4 alkyl,
R12 represents C1-6 alkyl, C3-6 cycloalkyl, benzene, or a four- to six-membered heterocyclic ring, wherein the C3-6 cycloalkyl, the benzene, and the four- to six-membered heterocyclic ring each independently may be substituted with halogen, C1-4 alkyl, or C1-4 alkoxy,
R14 represents a hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, benzene, or benzyl, wherein the C1-6 alkyl may be substituted with one to three R19, wherein, when a plurality of R19 exists, the plurality of R19 each independently may be the same or different, and
R19 represents C1-4 alkoxy, —CONH(C1-4 alkyl), —CON(C1-4 alkyl)2, or a five- or six-membered monocyclic aromatic heterocyclic ring which may be substituted with a substituent selected from the group consisting of C1-4 alkyl and C1-4 haloalkyl,
wherein the (C1-4 alkyl)2 in R19 represents two independent C1-4 alkyl groups which may be the same or different,
R15 represents C1-6 alkyl, C3-6 cycloalkyl, benzene, or benzyl,
R16 represents a hydroxyl group or C1-4 alkoxy,
each R17 independently represents a hydrogen atom, C1-6 alkyl, or C3-6 cycloalkyl, and
R18 represents halogen, C1-6 alkyl, C3-6 cycloalkyl, C1-4 alkoxy, oxo, nitrile, a hydroxyl group, hydroxymethyl, 1-methyl-1-hydroxyethyl, (C1-4 alkyl)SO2—, a four- to six-membered heterocyclic ring, (C1-4 alkyl)NH—, or (C1-4 alkyl)2N—,
wherein the (C1-4 alkyl)2 in R18 represents two independent C1-4 alkyl groups which may be the same or different,
m represents an integer of 1 to 4,
n represents an integer of 0 to 4,
p represents an integer of 0 to 2,
q represents an integer of 0 to 6,
r represents an integer of 0 to 6,
s represents an integer of 0 to 4,
t represents an integer of 0 to 2, and
R2, R3, R4, and R5 each independently may be the same or different when p, q, r, and s are each an integer of 2 or more,
wherein the cancer is treated by inhibiting prostaglandin E2 receptor 4 (EP4) and by inhibiting an immune checkpoint molecules; and
wherein the cancer is leukemia, malignant lymphoma, multiple myeloma, myelodysplastic syndrome, head and neck cancer, esophageal cancer, esophageal adenocarcinoma, stomach cancer, duodenal cancer, colorectal cancer, colon cancer, rectal cancer, liver cancer, gallbladder/bile duct cancer, biliary tract cancer, pancreatic cancer, thyroid cancer, lung cancer, breast cancer, ovarian cancer, cervical cancer, corpus uteri cancer, endometrial cancer, vaginal cancer, vulvar cancer, renal cancer, renal pelvis/ureter cancer, urothelial cancer, penile cancer, prostate cancer, testicular tumor, osteosarcoma/soft tissue sarcoma, malignant bone tumor, skin cancer, thymoma, mesothelioma, or blood cancer.

US Pat. No. 11,065,224

MODIFIED RELEASE GAMMA-HYDROXYBUTYRATE FORMULATIONS HAVING IMPROVED PHARMACOKINETICS

Flamel Ireland Limited, ...


1. A pharmaceutical composition that releases gamma-hydroxybutyrate in the blood stream of a human subject, wherein the composition is designed to be administered only once per night, wherein the composition is effective to induce sleep for at least six consecutive hours, and wherein upon administration to a human subject approximately two hours after a standardized evening meal andat a dose equivalent to 4.5 g or 6.0 g of sodium oxybate, the composition yields a plasma concentration versus time curve bioequivalent to the plasma concentration versus time curve depicted in FIG. 12 for the corresponding dose;
at a dose equivalent to 4.5 g, 6.0 g, or 7.5 g of sodium oxybate, the composition yields a plasma concentration versus time curve bioequivalent to the plasma concentration versus time curve depicted in FIG. 13 for the corresponding dose; or
at a dose equivalent to 4.5 g, 7.5 g, or 9.0 g of sodium oxybate, the composition yields a plasma concentration versus time curve bioequivalent to the plasma concentration versus time curve depicted in FIG. 90 for the corresponding dose.

US Pat. No. 11,065,219

TREATMENT OF NERVOUS SYSTEM DISORDERS USING COMBINATIONS OF RXR AGONISTS AND THYROID HORMONES

IO Therapeutics, Inc., H...


1. A method of treating aging-related neurodegeneration-associated demyelination or neuroinflammation, the method comprising administering to a human individual in need thereof a therapeutically effective amount of a RXR agonist and a thyroid hormone, wherein administration of the combination of the RXR agonist and the thyroid hormone treats the aging-related neurodegeneration in the individual, wherein the RXR agonist is 3,7-dimethyl-6(S),7(S)-methano,7-[1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphth-7-yl]2(E),4(E) heptadienoic acid, and has the structure of formula III:



and wherein the combination of RXR agonist and thyroid hormone causes a greater improvement in the aging-related neurodegeneration than the RXR agonist or thyroid hormone alone.

US Pat. No. 11,065,216

COMPOSITIONS AND METHODS FOR REGULATING BODY WEIGHT AND METABOLIC SYNDROMES

Purdue Research Foundatio...


1. A method for suppressing food intake of an obese subject, the method comprising parenterally administering to the obese subject in need of the suppression of food intake a composition comprising an effective amount of avasimibe that non-selectively inhibits in vivo both acyl-coenzyme A:cholesterl acyltransferase 1 (ACAT1) and acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2), wherein the degree that the avasimibe inhibits ACAT1 is less than the degree that the avasimibe inhibits ACAT2.

US Pat. No. 11,065,212

METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING CALCIPHYLAXIS

Epizon Pharma, Inc., New...


1. A method of treating elastinolysis associated with chronic obstructive pulmonary disease (COPD) in a human subject in need thereof, the method comprising administering to the human subject menaquinone-7 (MK-7) and/or menaquinol-7 (MKH2-7), whereupon the administration of the MK-7 and/or MKH2-7 increases a plasma level of Fetuin A relative to the plasma level of Fetuin A prior to administration, wherein the MK-7 and/or MKH2-7 is administered in a pharmaceutical composition.

US Pat. No. 11,065,207

ORAL DOSAGE FORM

Universiteit Gent, Ghent...


1. A pharmaceutical dosage form comprising one or more pellets having a core and a coating, wherein said core comprises at least 40% by weight active agent, from 1% to 15% by weight of partially hydrolyzed polyvinylalcohol (PVOH) with a degree of hydrolysis from about 70% to about 95%, and from 0.5% to 35% by weight microcrystalline cellulose (MCC).

US Pat. No. 11,065,204

OXIDIZED CELLULOSE MICROSPHERES

Covidien LP, Mansfield, ...


1. A composition comprising:a first microsphere including a biodegradable polymer; and
at least one second microsphere encapsulated in the first microsphere, wherein the at least one second microsphere includes an oxidized cellulose and at least one bioactive agent.

US Pat. No. 11,065,202

MULTI-COMPONENT NANOCHAINS

CASE WESTERN RESERVE UNIV...


1. A method of treating cancer in a subject, the method comprising:administering to the subject a multi-component nanochain that includes at least three nanoparticles linked together to form the nanochain, at least one nanoparticle of the nanochain having asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers, the nanoparticles being linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles, at least one nanoparticle comprising or being linked to an anti-cancer agent.

US Pat. No. 11,065,201

GEL FORMULATIONS FOR LOCAL DRUG RELEASE

TECHNICAL UNIVERSITY OF D...


1. A composition comprising non-water soluble carbohydrates and at least one triglyceride, wherein at least 50% of the non-water soluble carbohydrates are carbohydrates selected from derivatives of lactose, maltose, trehalose, or mixtures thereof, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration to form a gel, wherein the non-water soluble carbohydrates are saccharides which are modified with hydrophobic moieties to provide a water-excluding gel forming component that is promoted by hydrophobic interactions and/or physical non-covalent cross-links, wherein the liquid composition is homogenous and gelled composition is homogenous in appearance, for use as a medicament for drug delivery as a controlled release system of an active pharmaceutical ingredient in a human or animal body, and wherein the active pharmaceutical ingredient is a drug that modulates an immune response, wherein said at least one triglyceride is arranged in an amount of 10-50 wt % of the compositionwherein the non-water soluble carbohydrates are disaccharides with structures selected from




wherein R1, R2, R3, R4, R5, R6, R7, and R8 in formulae I, II and III are selected collectively from the group consisting of hydrogen, alkanoyl, hydroxyl-substituted alkanoyl, and acyloxy-substituted alkanoyl, alkanyl, hydroxysubstituted alkanyl and acyloxy substituted alkanyl; or wherein R1, R2, R3, R4, R5, R6, R7, and R8 are independently selected from the group consisting of hydrogen, alkanoyl, hydroxyl-substituted alkanoyl, and acyloxy-substituted alkanoyl, alkanyl, hydroxysubstituted alkanyl and acyloxy substituted alkanyl;
or wherein all groups of R1, R2, R3, R4, R5, R6, R7, and R8 are selected collectively from the group consisting of acetyl, isobutyryl or propionyl; or wherein R1, R2, R3, R4, R5, R6, R7, and R8 are independently selected from the group consisting acetyl, isobutyryl or propionyl; and
wherein both pure anomers and mixtures of ?- and ?-anomers of the above mentioned structural variations are claimed.

US Pat. No. 11,065,196

PROCESS FOR MAKING CONTROLLED RELEASE MEDICAL IMPLANT PRODUCTS


1. A multi-step method of making a large number of individual mammalian subcutaneous drug-containing implants wherein each implant comprises a matrix for releasing one or more self-contained biodegradable drugs on a controlled basis, wherein the method comprises;depositing at least portions of one or more layers of said large number of implants using at least one computer controlled 3-D printer within more than one enclosed clean depositing chamber including an enclosed, clean first depositing chamber;
moving said deposited layers from at least said first enclosed clean depositing chamber to at least a second enclosed clean depositing chamber; and
separating said deposited layers after a final depositing step to create said large number of implants.

US Pat. No. 11,065,195

TOPICAL COMPOSITION

MC2 Therapeutics Limited,...


1. An aqueous composition suitable for topical application comprising:a polyaphron dispersion comprising one or more surfactant, a continuous phase, and a discontinuous phase, wherein the continuous phase comprises water and the discontinuous phase comprises a pharmaceutically acceptable oil that is immiscible or substantially immiscible with the continuous phase, wherein the discontinuous phase comprises droplets, and wherein the droplets are dispersed in the continuous phase;
wherein the composition comprises 5% to 90% by weight of the water based on the total weight of the aqueous composition;
wherein the polyaphron dispersion further comprises (i) at least one of vitamin D or vitamin D analogue, and (ii) at least one corticosteroid;
wherein the (i) at least one of vitamin D or vitamin D analogue, and the (ii) at least one of corticosteroid are predominantly in the droplets.

US Pat. No. 11,065,190

COSMETIC COMPOSITION COMPRISING SOLUBILIZED PIGMENT AND METHOD FOR PREPARING THE SAME

Amorepacific Corporation,...


1. A lip cosmetic composition comprisinga toner pigment selected from the group consisting of disodium salt of 4-(2-sulfo-p-tolylazo)-3-hydroxy-2-naphthoic acid and calcium salt of 4-(2-sulfo-p-tolylazo)-3-hydroxy-2-naphthoic acid in an amount of 0.1 to 3 wt. %;
a first thickener in an amount of 0.01 to 2 wt %;
an acid in an amount of 0.01 to 2 wt %; and
a solubilizer in an amount of 0.1 to 5 wt %;
a second thickener in an amount of 0.01 to 3 wt %;
water; and
glycerin,
wherein the first thickener comprises one or more selected from the group consisting of ammonium acryloyldimethyltaurate/VP copolymer, hydroxyethyl acrylate/sodium acryloyldimethyltaurate copolymer, and polyacrylate-13;
wherein the second thickener comprises one or more selected from the group consisting of polyacrylate crosspolymer-6+xanthan gum; polyacrylate-13+xanthan gum; and acrylate copolymer+agar; and
wherein the lip cosmetic composition is transparent.

US Pat. No. 11,065,188

APPLICATIONS AND FORMULATIONS OF OPTIMIZED, MODIFIED HUMAN EMBRYONIC FERTILITY CULTURE MEDIA WITH BIGUANIDES AND/OR FUNCTIONAL EQUIVALENTS

AV Laboratories LLC, N. ...


1. A dermatological preparation comprising a simplex-optimized human embryonic fertility medium and biguanide or biguanide derivative wherein the preparation is an oil-in-water formulation for application for skin care, hair care, body care, dental procedures, anti-aging, and regenerative medicine.

US Pat. No. 11,065,182

RESIN COMPOSITE AND RESTORATION CONTAINING AZOLE-FUNCTIONALIZED SILICA


1. A resin composite, comprising:a polymerizable monomer;
a polymerization initiator system; and
azole-functionalized silica nanoparticles in an amount ranging from 5 wt % to 75 wt % relative to a total weight of the resin composite;
wherein the azole-functionalized silica nanoparticles are a ring-opening reaction product of:silica nanoparticles modified with epoxide groups; and
an azole moiety,
wherein the silica nanoparticle modified with epoxide groups is represented by formula (I)






wherein NP represents a silica nanoparticle;
n is a positive integer in a range of 1-6; and
m is a positive integer in a range of 2-1000.


US Pat. No. 11,065,181

SYRINGE-TO-SYRINGE COUPLER

NeoMed, Inc., Woodstock,...


1. A coupling for facilitating the transfer of fluids or medications, the coupling comprising:a centrally-positioned hub extending from a first end to a second end, each end of the hub comprising a male tip;
a fluid delivery conduit provided within the hub and extending between the first and second ends; and
a body outwardly offset from the hub;
at least one connecting member connecting the hub with the body; and
at least one engagement member for providing coupling engagement with a syringe, wherein the at least one engagement member extends from the at least one connecting member.

US Pat. No. 11,065,180

SYSTEMS AND METHODS FOR IDENTIFYING MEDICINES DEPOSITED IN A COMPARTMENT OF A PILL BOX ACCORDING TO A PRESCRIPTION


1. A stage system for identifying and validating drugs disposed, according to a prescription, in the compartments of a dispenser for a patient and/or for a person accompanying the patient, said system comprising:a first dispenser for the patient and/or for a person accompanying the patient;
a second dispenser oversized compared to the size of the first dispenser, including the same number of compartments or a number of compartments greater than the number of compartments of the first dispenser;
a connection device between the compartments of the first dispenser and those of the second dispenser, said connection device allowing the transit of one or several drugs, from one compartment of the second dispenser towards its opposite of the first dispenser, the lower part of a compartment of the second dispenser being configured so as to have a releasing device letting, on request, the drugs of one of the compartments of the second dispenser migrate to the opposite compartment of the first dispenser;
a measuring device configured to collect and analyze drug identification characteristics, the drugs being disposed so as not to overlap, in each of the compartments of the second dispenser: whether one of the drugs present in one compartment is separated by a space from one or several neighboring drugs or whether it is in contact with one or several adjacent drug(s);
a transmission device configured to transfer the analyzed or non-analyzed identification characteristics collected by the measuring device and relating to the drugs present in the compartments of the second dispenser, to a computation unit; and
the computation unit being configured to:
isolate the identification characteristics received from the transmission device for each of the drugs actually present in one compartment of the second dispenser, and identify each of these drugs,
compare the identification characteristics that have been isolated with the information contained in a database of the characteristics of the drugs having to be present, according to the prescription, in one of the compartments of the second dispenser, and said identification and validation system being configured to emit a message according to which:
all the drugs actually present in each of the compartments of the second dispenser correspond or not to those that, according to the prescription, should be there;
the number of drugs actually present in one compartment corresponds to the number of drugs that, according to the prescription, should be there;
the total number of drugs present in all the compartments of the second dispenser corresponds to the total number of drugs that, according to the prescription, should be in the second dispenser;
the weight of the drugs present in one compartment corresponds to the weight of the drugs that, according to the prescription, should be there; and/or
the weight of all the drugs present in all the compartments of the second dispenser corresponds to the total weight of all the drugs that, according to the prescription, should be there.

US Pat. No. 11,065,179

THERAPEUTIC POOL FLOTATION DEVICE AND THERAPEUTIC METHOD OF USE THEREOF


1. A therapeutic flotation device, comprising:a plurality of buoyant float elements, each of the buoyant float elements having an aperture aligned along the center of a cross-section thereof, each of the buoyant float elements having a cross-section that is one of triangular, crescent-shaped, oval, and tear drop-shaped; and
a flexible member having a first end and a second end, the flexible member coupling each of the buoyant float elements such that the buoyant float elements are serially aligned along the flexible member, the first end of the flexible member secured to the second end of the flexible member;
wherein the flexible member is coupled to each of the buoyant float elements by being sequentially passed through the apertures of each buoyant float element.

US Pat. No. 11,065,178

SPINAL MASSAGE DEVICE


1. A personal massage retrofit device comprising: a housing with a front side and a rear side, wherein the rear side of the housing comprises a guide slot comprised of two guide slot pads configured to engage a supporting structure to restrict lateral movement of the device while allowing vertical movement of the device and the front side of the housing comprises a deformable material for receiving a portion of a personal massage device; a plurality of retaining straps wherein the plurality of retaining straps are attached to the housing and designed to retain a motorized personal massage device; and a plurality of retaining rings wherein the retaining rings are attached to the housing and wherein the retaining rings are configured to receive a strap handle that controls the vertical position of the device while engaged with a supporting structure.

US Pat. No. 11,065,177

SEXUAL AID APPARATUS WITH SAFETY DEVICE


1. A sexual aid apparatus with a safety feature, the apparatus comprising:(a) a shaft element configured to emulate a human penis and to be placed against genitals or inside a human orifice;
(b) an electric vibrating motor located within the shaft element, the electric vibrating motor configured for vibrating the shaft element so as to produce sensation in a user when used against genitals or inside a human orifice;
(c) a flexible cord coupled to a distal end of the shaft element, the cord configured for having a tensile strength of at least 20 pounds per square inch;
(d) one or more spherical elements coupled to the cord and located between ends of the cord, the one or more spherical elements configured for insertion into a human orifice and for producing sensation in the user; and
(e) one or more crystal elements coupled to the cord and located between the ends of the cord, the one or more crystal elements configured for insertion into a human orifice and for producing sensation in the user.

US Pat. No. 11,065,176

PRESSURE FIELD STIMULATION DEVICE

UCCELLINI LLC, Bend, OR ...


1. A stimulation device, comprising:a cup formed of a flexible resilient material comprising an anchor wall, a cavity and a buckle region comprising a buckle region wall; and
a driver configured to intermittently compress a volume of the cavity of the cup from a first volume to a second volume;
wherein the buckle region wall is configured to expand the cup from the second volume to the first volume, in between intermittent repetitions of the compressing, in such a way that causes a thud force through the anchor wall;
wherein a thickness of the anchor wall is greater than a thickness of the buckle region wall.

US Pat. No. 11,065,175

LEG MASSAGER

DAITO ELECTRIC MACHINE IN...


1. A leg massager comprising:a lower massaging system that massages a massage target area of user's leg including at least user's foot;
an upper massaging system that massages an upper massage target area located above the massage target area which is massaged by the lower massaging system;
a driving mechanism that drives the upper massaging system and the lower massaging system; and
a rockably supporting portion that supports the upper massaging system for rocking motion about a horizontal axis,
wherein the upper massaging system is mounted within an elongated upper casing, and the lower massaging system is mounted within a lower casing,
wherein the rockably supporting portion, which is located toward a top of the lower casing, supports a base end of the upper casing for free rocking motion to impart rising movement to a front end of the upper casing via a horizontally oriented rock shaft,
wherein the upper massaging system has a first massaging member in elongated plate form that performs massage operation for the massage target area, and
wherein, when the upper casing is tilted forwardly to adjacent the lower casing, then the first massaging member housed within the upper casing faces frontward, and, when the upper casing is raised away from the lower casing, then the first massaging member housed within the upper casing faces upward.

US Pat. No. 11,065,174

WEARABLE INTERACTIVE SYSTEM AND METHOD OF NON-OPIOID AND DRUG-FREE PAIN CONTROL


1. A wearable sleeve configured to be worn on a limb of a user, the wearable sleeve comprising:a tubular sleeve body, which is flexible and elongated along an axis; and
a series of base surfaces secured to the tubular sleeve body such that each of the series of base surfaces is spaced from adjacent ones of the series of base surfaces along a direction parallel to the axis, each of the base surfaces sized so as to encompass less than an entire circumference of the tubular sleeve body;
a series of vibration sources disposed on respective ones of the series of base surfaces and thereby attached to the tubular sleeve body, and
a ring of LEDs configured to expose skin on the limb of the user to light, the ring of LEDs disposed on at least one of the series of base surfaces of the wearable sleeve that supports at least one of the series of vibration sources;
wherein the series of base surfaces are secured to the tubular sleeve body at positions that align with a lymphatic drainage path in the limb of the user when the wearable sleeve is positioned on the limb.

US Pat. No. 11,065,173

MASSAGE APPARATUS


1. A handheld apparatus for massaging a user comprisinga linear and elongate body having a proximal end and a distal end, wherein a length of the linear and elongate body extends from the proximal end to the distal end, wherein the proximal end of the linear and elongate body is connected to a handle, the linear and elongate body having a longitudinal body axis, wherein the distal end of the linear and elongate body is coupled to a proximal end of a massage sphere or massage wheel; and
a support rotatably attached to the linear and elongate body at an attachment point at a first distance from a distal end of the massage sphere or massage wheel, where the support rotates about a support rotation axis that is perpendicular to the longitudinal body axis, where the support is hook shaped and includes a planar surface at a second distance from the attachment point, where the second distance is greater than the first distance,
such that when the planar surface is rotated to intersect the longitudinal body axis, the longitudinal body axis is normal to the planar surface and a gap between the planar surface and the distal end of the massage sphere or massage wheel along the longitudinal body axis comprises a distance that is equal to the second distance minus the first distance,
such that when the apparatus accepts a part of the user between the distal end of the massage sphere or massage wheel and the planar surface during operation of the apparatus, the distal end of the massage sphere and massage wheel and the planar surface contact the part of the user at different distances along the longitudinal body axis, and
such that when the handle is moved relative to the support, a force along the longitudinal body axis is applied to the part of the user by the distal end of the massage sphere or the massage wheel and the planar surface.

US Pat. No. 11,065,172

CUSHIONING BODY FOR A LEG REST OF A ROLLATOR WALKING AID


1. A cushioning body for a leg rest of a rollator walking aid, wherein the cushioning body is an elastic molded body attachable to a support member of the leg rest of the walking aid and comprises an upper side and a lower side, with the upper side facing and being in contact with a leg of a person when the person is using the walking aid, wherein the upper side along the entire length thereof is trough-shaped and the depression is formed on a concave side of the trough and wherein at least one of the upper side and the lower side of the cushioning body has a depression, with the depression being configured as a recess or as an area in which material of the molded body has a lower density and with a protuberant part of the anterior surface of the knee and of the neighboring portion of the lower leg being received in the depression when the leg of the person is resting on the cushioning body.

US Pat. No. 11,065,171

ASSISTIVE GLOVE FOR DAILY ACTIVITIES OF STROKE PATIENT

Southern Taiwan Universit...


1. An assistive glove for daily activities of a stroke patient, comprising:a main body having a thumb sleeve, at least one finger sleeve, a palm portion connected at a distal side thereof to the thumb sleeve and the at least one finger sleeve, and a wrist portion connected to a proximal side of the palm portion;
a first pulling member having a first hook disposed on the palm portion corresponding to the thumb sleeve;
a second pulling member having at least one second hook disposed on the palm portion corresponding to the at least one finger sleeve; and
a plurality of circular strings hung on the first hook and the at least one second hook and fixed to the thumb sleeve and the at least one finger sleeve respectively.

US Pat. No. 11,065,170

SMART MEDICAL REHABILITATION DEVICE

HEFEI UNIVERSITY OF TECHN...


1. A limb rehabilitation training system, comprising:a mechanical structure module, comprising:a driving unit; and
a linkage unit arranged on a frame; and

a function module, comprising:a sensing unit that collects body function data, wherein the body function data comprises pedal pressure, exercise duration, and exercise mileage;
a mobile terminal; and
a data-processing cloud terminal comprising a data-processing unit and a rehabilitation database,
wherein the sensing unit comprises a single-chip microcomputer, a pressure sensor that collects the pedal pressure data, a time sensor that collects the exercise duration data, a velocity sensor that collects the exercise mileage data, an amplification circuit and an A/D conversion circuit that amplifies and transmits body function data collected by the pressure, time and velocity sensors to the single-chip microcomputer, wherein the single-chip microcomputer sends the body function data to the mobile terminal,
wherein the mobile terminal collects physiological data of the training object and sends both the body function data and the physiological data to the data-processing cloud terminal, wherein the physiological data include body height, body weight, and age of the training object, and

wherein the data-processing cloud terminal performs a first matching between data collected by the sensing unit, and expert data stored in the data-processing cloud terminal to provide a first rehabilitation training program, and stores the first rehabilitation training program in the data-processing cloud terminal; wherein the expert data comprise rehabilitation training programs associated with physiological data and/or body function data of training objects, and
wherein the data-processing cloud terminal performs a second matching between physiological data of the training object collected by the mobile terminal and the first rehabilitation training program to generate a second rehabilitation training program, stores the second rehabilitation training program in the data-processing cloud terminal, and sends the second rehabilitation training program to the mobile terminal as a recommended rehabilitation training scheme, wherein the second rehabilitation training program comprises a duration of each training session and/or a number of training sessions per day and/or a training cycle and/or an exercise mileage and/or support provided by a pedal,
wherein the mechanical structure module at least comprises: a groove plate for supporting a cam roller, the pedal for supporting the weight of the training object and driving the lower limb of the training object to move, a link for transmitting kinetic energy to the pedal, a rocker for supporting the link, a connecting bulge or driving a guide shaft to rotate, a linear bearing for supporting the guide shaft, the guide shaft for driving a slider to rotate, the slider for driving the link to operate, an axis pin for connecting the link and the slider, and the cam roller for making the slider move along a groove trajectory of the groove plate; wherein the pedal and the link are rigidly connected, while the link is hinged to the first rocker and the axis pin respectively, the rocker is hinged to the frame, the connecting bulge is provided with two parallel columnar through holes, the linear bearing is received in the columnar through hole, the guide shaft passes through the linear bearing, the guide shaft and the slider are rigidly connected to each other, and the cam roller is rigidly connected to the connecting bulge through the axis pin, and the cam roller performs curved movement along the groove plate, as the curvature radius changes, the guide shaft performs linear movement with respect to the connecting bulge, the linear bearing is arranged in the connecting bulge for reducing mechanical wear between the guide shaft and the connecting bulge, thereby improving the service life.

US Pat. No. 11,065,169

CONVERTIBLE EXAMINATION TABLE


1. An examination table comprising:at least one planar table member having an examination face and a non-examination face, the table member adjustable between a horizontal orientation for medical evaluation of a patient and a vertical orientation; and
a base fashioned as a support frame for supporting the table member when horizontally oriented, the base comprising a front frame support member, a first end member and a second end member, a back frame support member horizontally interposed between and connected to the first and second end members, forming a substantially rectangular, free-standing structure, wherein the front frame support member and first and second end members are substantially vertically oriented relative to a floor and the first and second end members and back frame support member being of substantially the same height to provide support for the planar table member when in the horizontal orientation; and
at least one substantially planar seating member disposed between and connected to the support frame to form a horizontal seating surface suitable for seating patients;

wherein the table member is hingedly affixed to the horizontally interposed back frame support member, allowing the table member to move between the vertical and horizontal orientations, whereby the examination face of the table member faces up when the table member is pivoted forward to the horizontal orientation and affords access to the horizontal seating surface when in the vertical orientation.

US Pat. No. 11,065,168

LEG ASSEMBLY FOR HEIGHT ADJUSTABLE PATIENT SUPPORT

Stryker Corporation, Kal...


1. A height adjustable patient support comprising:a frame;
an actuator;
a leg assembly, said actuator operable to pivot said leg assembly relative to said frame to raise or lower said frame between a lowermost position and an uppermost position; and
a spring assembly having a spring with a spring stroke, said spring assembly being independent of and spaced from said actuator, wherein said leg assembly is decoupled from said spring assembly, but when in said lowermost position said leg assembly applies a compressive force on said spring wherein said spring generates a spring force to bias said leg assembly toward said uppermost position to thereby reduce the force needed to raise the frame from said lowermost position over a range of motion, and said leg assembly no longer applying said compressive force on said spring when said leg assembly has moved beyond said range of motion.

US Pat. No. 11,065,167

DYNAMIC SEATING COMPONENTS FOR WHEELCHAIRS

American Track Roadster, ...


1. A pivotable leg connection for a mobile seating device, the pivotable leg connection comprising:a connection element configured to be received in a receiver of the mobile seating device;
a pin;
two side plates rigidly connected to the connection element, wherein at least one of the two side plates comprises a curved outer edge, and defines an axle opening and at least one pin opening disposed between the curved outer edge and the axle opening, wherein the pin opening is configured to receive the pin;
an axle disposed between the two side plates and extending from the axle opening;
a leg pivotably connected to the axle, wherein when the pin is inserted into the pin opening, the pin sets a position of the leg; and
at least one biasing element disposed about the axle and between the two side plates, wherein the biasing element is configured to bias the leg towards a biased position.

US Pat. No. 11,065,166

MOTION-BASED POWER ASSIST SYSTEM FOR WHEELCHAIRS

MAX MOBILITY, LLC, Leban...


1. A power assist system for wheelchairs with an axle, the power assist system comprising:a motion sensing system comprising one or more motion-sensitive instruments configured to measure the motion of the power assist system; and
a drive system comprising one or more electric motors, one or more drive wheels, and an axle mounting attachment, wherein the motion-sensitive instruments are further configured to measure a change in rotational position of the one or more drive wheels to determine the motion of the power assist system;
wherein the motion sensing system and the drive system are contained in a housing that is adapted to pivotally attach to an axle extending between two wheels of a wheelchair.

US Pat. No. 11,065,165

CHILD SANITARY NAPKIN METHOD AND APPARATUS


1. A method, comprising:fabricating a system including a child sanitary napkin including disposable child sanitary napkin underwear;
wherein fabricating the child sanitary napkin includes a plurality of layers including an exterior waterproof non porous outer layer, a thin superabsorbent polymer layer, an odor absorbing activated charcoal pad layer and an interior soft cotton covering layer;
wherein fabricating the child sanitary napkin includes imprinting a product barcode on an outer surface of the waterproof non porous outer layer and embedding an RFID chip into the plurality of layers for tracking a wearer's location via a digital device cellular connection;
contouring a shape of the child sanitary napkin to conform to a female anatomical groin area;
flaring front and rear terminus areas of the child sanitary napkin to increase an adhesive bonding area;fabricating the child sanitary napkin according to children's clothing and age sizes for providing a snug fit to prevent leakage; and

applying to the outer surface at least one decorative image.

US Pat. No. 11,065,164

SMART BANDAGE FOR ELECTROCHEMICAL MONITORING AND SENSING USING FABRIC-INTEGRATED DATA MODULATION

The Florida International...


1. An electronic system for remote sensing and monitoring of wound healing in a wound having an associated wound fluid, the electronic system comprising:a first textile antenna configured to receive an RF power signal;
a fabric integrated rectifying circuit configured to convert the RF power signal to a rectified DC supply voltage, the electronic system being configured to operate normally without a power source;
a textile based electrochemical sensor configured to receive power from the rectified DC supply voltage and output an electric signal in response to one or more wound health data values of the associated wound fluid;
a textile based voltage controlled oscillator (VCO) configured to receive power from the rectified DC supply voltage and modulate the electric signal output by the textile based electrochemical sensor into an RF frequency signal; and
a second textile antenna configured to transmit the RF frequency signal modulated by the textile based VCO.

US Pat. No. 11,065,163

FEMININE HYGIENE ARTICLE WITH IMPROVED WINGS


1. A feminine hygiene article having a chassis comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet, a longitudinal centerline and a lateral centerline perpendicular to the longitudinal centerline, the feminine hygiene article further comprising:a first wing extending laterally outboard of the chassis having a first leading edge extending outboard of the chassis, a first trailing edge extending outboard of the chassis and one or more edges connecting the first leading edge and the first trailing edge, the first wing further comprising a first proximal zone and a first distal zone and a first bisecting line forming at least a portion of a boundary between the first distal zone and the first proximal zone, wherein the first wing is asymmetric about the first bisecting line, wherein the first distal zone is disposed more outboard of the chassis than the first proximal zone, and wherein the first proximal zone forms the uppermost portion of the first wing;
a second wing extending laterally outboard of the chassis having a second leading edge extending outboard of the chassis, a second trailing edge extending outboard of the chassis and one or more edges connecting the second leading edge and the second trailing edge, the second wing further comprising a second proximal zone and a second distal zone and a second bisecting line forming at least a portion of a boundary between the second distal zone and the second proximal zone, wherein the second wing is asymmetric about the second bisecting line, wherein the second distal zone is disposed more outboard of the chassis than the second proximal zone, and wherein the second proximal zone forms the lowermost portion of the second wing;
a first visual signal disposed in the first distal zone; and
a second visual signal disposed in the second distal zone.

US Pat. No. 11,065,162

AMPUTATED LEG MEDICAL WRAP APPARATUS


9. A belt and amputated leg medical wrap apparatus combination comprising:a waist belt, the waist belt having a right end having a buckle and a left end having a clasp, the buckle and the clasp being selectively engageable to secure the waist belt around a user's waist;
a bottom pad, the bottom pad having a bottom inner surface, a bottom outer surface, a back portion, a bottom portion, a right side portion, and a left side portion, the bottom pad being cupped such that the bottom portion, the right side portion, and the left side portion extend upwards from the bottom portion and are configured to cover an underside, a medial side, and a lateral side of a user's amputated leg stump;
a pair of straps coupled to the bottom pad, each of the pair of straps being coupled to the bottom outer surface of the back portion and having a right extension and a left extension, the pair of straps comprising a top strap coupled adjacent an upper edge of the bottom pad and a bottom strap coupled proximal the bottom portion;
a pair of top pads coupled to the pair of straps, the pair of top pads having a top inner surface and a top outer surface, the pair of top pads comprising a right top pad and a left top pad coupled to the right extension and the left extension, respectively, of the top strap and the bottom strap, the top strap and the bottom strap being coupled adjacent a top edge and a bottom edge of the pair of top pads, respectively, the right top pad having a first hook-and-loop fastener coupled to the top inner surface and the left top pad having a second hook-and-loop fastener coupled to the top outer surface, the first and second hook-and-loop fasteners being selectively engageable and configured to secure the apparatus to the user's amputated leg stump, the first hook-and-loop fastener being a strip occupying 20%-30% of the top inner surface of the right top pad and adjacent an outer edge of the right top pad, the second hook-and-loop fastener being continuously disposed on the entire top outer surface of the left top pad; and
a belt strap coupled to the bottom pad, the belt strap having a belt strap inner surface coupled to the bottom outer surface of the bottom portion and comprising a right belt strap extension and a left belt strap extension each having a looped top end extending past the upper edge of the bottom pad, the looped top end of each of the right belt strap extension and the left belt strap extension being formed by coupling a distal end of each of the right belt strap extension and the left belt strap extension to the belt strap inner surface, the looped top end of each of the right belt strap extension and the left belt strap extension receiving the waist belt.

US Pat. No. 11,065,161

ABSORBENT ARTICLE AND METHOD FOR MANUFACTURING AN ABSORBENT ARTICLE

Essity Hygiene and Health...


1. An absorbent article comprising a main body having a liquid-permeable topsheet, a liquid-impermeable backsheet and an absorbent core sandwiched between said topsheet and said backsheet, said main body being arranged along a longitudinal axis (Y1) and a transversal axis (X1) extending in a perpendicular direction in relation to the longitudinal axis (Y1), said main body defining a front portion, a back portion and a crotch portion; wherein said article comprises a first wing and a second wing extending outwardly from said crotch portion of the main body in opposite directions in an asymmetric manner with reference to the longitudinal axis (Y1), and generally along said transversal axis (X1), said wings being provided with first and second fastening means configured for fastening said wings to a garment when being folded over said main body and towards said longitudinal axis (Y1), wherein each wing includes a periphery defined by an outer edge that faces away from the longitudinal axis (Y1) in an unfolded state of the article and at least one side edge that faces inwardly towards the longitudinal axis (Y1) in the unfolded state of the article and connects the outer edge to the main body, with the outer edge of each wing defining at least one arc of a circle coinciding with a section of the outer edge and having a defined radius (r), said section extending between a first point on the outer edge and a second point along said outer edge where said arc no longer coincides with said outer edge, wherein said radius (r) is within an interval of 50-300 mm, and wherein said outer edge includes said first point in the form of a transversally outermost point of the wing, said section extending from said outermost point and to said second point, and wherein the outer edge of each wing is formed with no straight edge sections.

US Pat. No. 11,065,160

TREATED NONWOVEN HAVING AN AFFINITY FOR AN ACTIVE INGREDIENT

AVINTIV Specialty Materia...


1. A nonwoven comprising:(a) at least a first spunbond nonwoven layer comprising a fiber blend of round cross-sectional shaped spunbond fibers and non-round cross-sectional shaped spunbond fibers, wherein the round cross-sectional shaped fibers have an average diameter less than 10 microns; and
(b) an active ingredient disposed substantially at a surface of the fiber blend;
wherein the nonwoven is devoid of a meltblown layer; and
wherein the first nonwoven has a strike through time that is less than 10 seconds for all three insults when tested per WSP 70.7(05); and wherein the first nonwoven layer has a theoretical surface area of greater than about 4200 cm2 per gram of fiber blend.

US Pat. No. 11,065,159

ABSORBENT ARTICLE

DAIO PAPER CORPORATION, ...


1. An absorbent article comprising:a liquid permeable topsheet;
a backsheet;
an absorbent body provided between the liquid permeable topsheet and the backsheet; and
a second sheet provided between the liquid permeable topsheet and the absorbent body, wherein
the absorbent article has slits that penetrate in the thickness direction thereof, the slits being respectively formed on both side portions of the absorbent body along a longitudinal direction thereof,
the absorbent body includes a body-fluid-expelling-portion corresponding region, the body-fluid-expelling-portion corresponding region being included between the slits,
the second sheet is provided along an inner surface of the slits,
the second sheet is folded back at the backsheet within the slits such that respective recesses are provided within the slits, and
the second sheet is patterned to include two first sheet portions and a second sheet portion, the first sheet portions defining the respective recesses provided by folding back the second sheet, each first sheet portion having water-repellent properties, the second sheet portion being continuously located between the first sheet portions and being interposed between the liquid permeable topsheet and the absorbent body, and the second sheet portion having hydrophilic properties.

US Pat. No. 11,065,158

SURGICAL SPONGE

International Private Ban...


1. A surgical sponge, comprising:sponge material configured in an elongate sponge having a length and having multiple compressed layers and a flattened shape characterized by a generally flat upper surface along the length of the sponge, a generally flat lower surface along the length of the sponge, with the sponge having a thickness that is substantially less than a width of the sponge, one reduced dimension end of the elongate sponge having an end length and reducing in dimension distally along the end length;
stitches along the length of the sponge to encircle and to compress the sponge material, thereby maintaining the layers in compression and inhibiting swelling of the sponge when saturated with fluids to maintain the flattened shape of the sponge when the sponge is saturated with fluids; and
a length of stitch material extending from the reduced dimension end to provide a structure that is engageable for use in positioning or removal of the sponge during a surgical procedure.

US Pat. No. 11,065,157

TAMPON APPLICATOR

Essity Hygiene and Health...


1. An applicator for a tampon, comprising:an inner tube and an outer tube, the inner tube being slideable within the outer tube, the applicator having a forward end and a rear end, wherein the inner tube comprises a tampon at least partially disposed in the inner tube, a front end configured to engage with a rear end of the tampon, with the inner tube being located entirely rearwardly of the tampon when the tampon is being pushed out of the outer tube of the applicator during movement of the inner tube relative to the outer tube in a direction toward the forward end of the applicator, and at least one flange disposed on the inner tube and protruding into an interior space within the inner tube and being configured to engage the tampon when it is at least partially disposed in the inner tube, wherein the at least one flange is located at between 10% and 90% of the longitudinal length of the inner tube.

US Pat. No. 11,065,156

LENTICULAR LASER INCISION FOR LOW MYOPIA AND/OR HYPEROPIA PATIENTS

AMO DEVELOPMENT, LLC, Sa...


1. A method for creating lenticular incisions to correct low myopic/hyperopic patients using an ophthalmic surgical laser system, the method comprising:placing a patient interface device in contact with a cornea of a patient's eye to applanate the cornea;
generating a pulsed femtosecond laser beam;
delivering the pulsed femtosecond laser beam into a stroma of the cornea;
deflecting, by an XY-scan device, the pulsed laser beam;
modifying, by a Z-scan device, a depth of a focus of the pulsed laser beam; and
calculating, by a controller, an initial top lenticular shape, an initial bottom lenticular shape, wherein the initial top lenticular shape and the initial bottom lenticular shape define an initial space between them, and a shape of an added space, wherein the initial top lenticular shape and the initial bottom lenticular shape are calculated based on a predetermined correction power, wherein the shape of the added space has a uniform thickness part with a uniform first thickness and a lenticular part with a second thickness at its center, wherein the second thickness is calculated based on a shape difference between the applanated cornea and the cornea in an unapplanated state, and wherein the shape of the added space introduces zero correction power in the cornea in the unapplanated state;
calculating, by the controller, a top lenticular incision shape based on the initial top lenticular shape and the shape of the added space, and a bottom lenticular incision shape based on the initial bottom lenticular shape and the shape of the added space;
controlling, by a controller, the XY-scan device and the Z-scan device to form an incised lenticule in the cornea, by incising, while the cornea is applanated by the patient interface device:a top lenticular incision in the stroma of the cornea, having the calculated top lenticular incision shape and a circumferential periphery;
a bottom lenticular incision in the stroma of the cornea, symmetric to the top lenticular incision, having the calculated bottom lenticular incision shape and a circumferential periphery; and
a transition ring or side cut incision intersecting the circumferential periphery of the top lenticular incision and the circumferential periphery of the bottom lenticular incision; and

removing the patient interface device from the cornea.

US Pat. No. 11,065,155

DIAGNOSTIC AND SURGICAL LASER DEVICE UTILIZING A VISIBLE LASER DIODE AND A BEAM PATTERN GENERATOR

VISUMEDICS, INC., Readin...


1. A method for diagnosing and/or treating a medical condition of a subject wherein each of a plurality of aiming light beams can be disposed on a plurality of positions on an inner portion of an eye of a subject, wherein a position is accessible via a shift of each aiming light beam incidencing upon an inner portion of an eye in at least one direction via an intermediate image created by a focusing lens, and wherein a treatment laser beam follows generally the same path as an aiming light beam such that the treatment laser beam effects treatment on the eye of the subject.

US Pat. No. 11,065,154

BLEB DRAINAGE DEVICE, OPHTHALMIC PRODUCT AND METHODS


1. A method of treating glaucoma in an eye of a patient including the step ofinserting into the patient's retrobulbar space to drain fluid from an intraocular chamber of the patient's eye a terminal open beveled end of a flexible tubular member with a circular cross-section that forms a passageway in the tubular member terminating in said beveled open end,
said passageway defined at least in part by a wall of the flexible tubular member terminating in said open end, said wall including a plurality of openings at said open end,
said plurality of openings configured and positioned so that, when said open end and plurality of openings are within the retrobulbar space, the fluid exits through said openings and open end and drains into the retrobulbar space.

US Pat. No. 11,065,153

FLUIDICS CASSETTE FOR OCULAR SURGICAL SYSTEM


1. An eye treatment cassette for use with an eye treatment console, the eye treatment console comprising a receptacle, a peristaltic pump exposed to the receptacle to facilitate a positive displacement aspiration functionality, a vacuum source that is part of a vacuum-based system and coupleable to the receptacle to induce a vacuum-based aspiration functionality, and a cassette functional indicator detector, the eye treatment cassette comprising:a cassette frame;
an aspiration pathway coupleable to at least one of the peristaltic pump or the vacuum source when the cassette frame is mounted in the receptacle; and
a cassette functional indicator that signals a functionality of the eye treatment cassette to the detector of the console so as to allow the console to selectively drive at least one of the positive displacement aspiration with the peristaltic pump or vacuum-based aspiration with the vacuum-based system based on the functionality of the eye treatment cassette.

US Pat. No. 11,065,152

SYSTEMS AND METHODS FOR THE TREATMENT OF EYE CONDITIONS

ALCON INC.


1. A system for treating meibomian gland disease of an eyelid, comprising:a back plate positionable between an eyeball and an eyelid of a patient;
a compressive element mechanically coupled to the back plate, wherein the back plate and the compressive element collectively define an aperture between the back plate and the compressive element such that the aperture provides a line of sight that permits viewing of an eyelid margin by a clinician through the aperture when the back plate is positioned between an eyeball and an eyelid of a patient;
a light-emitting device that emits light energy;
a housing, wherein the back plate, the light-emitting device, and the compressive element are mechanically coupled to the housing.

US Pat. No. 11,065,151

THERAPEUTIC AGENT FORMULATIONS FOR IMPLANTED DEVICES

ForSight Vision4, Inc., ...


1. A therapeutic device comprising:(i) a flowable formulation provided within the therapeutic device, the formulation comprising: a therapeutic agent having a molecular weight; and a stabilizer selected based on the stabilizer having a molecular weight that is at least 10% of the molecular weight of the therapeutic agent; wherein the molecular weight of the stabilizer is at least 10% of the molecular weight of the therapeutic agent such that the half-life of the stabilizer when placed in the device comprises at least about 50% of the half-life of the therapeutic agent when placed in the device;
(ii) a retention structure near a proximal end of the therapeutic device having an indentation sized to receive a sclera;
(iii) a refillable, non-permeable chamber coupled to the retention structure and configured to hold the formulation, the chamber having at least one opening to release the therapeutic agent to a vitreous humour when said device is implanted in any eye;
(iv) a penetrable barrier disposed through the retention structure and the indentation into a proximal end of the chamber; and
(v) a rigid porous structure placed in the at least one opening, the rigid porous structure comprising sintered metal, ceramic, glass, or plastic material allowing for molecular diffusion of the therapeutic agent and the stabilizer from the chamber into the vitreous humor for an extended amount of time.

US Pat. No. 11,065,150

DUAL BALLOON FLUID ENDOMETRIAL TREATMENT OF UTERINE TISSUE

Gyrus Acmi, Inc., Westbo...


1. A method comprising:providing or obtaining a medical device comprising a first balloon, a second balloon arranged within the first balloon and having at least one rupture valve, and a fluid-tight intermediary space between the first balloon and the second balloon;
wherein the at least one rupture valve is configured to rupture in response to at least a predefined pressure being applied to an outer surface of the second balloon;
inserting the medical device into a uterine cavity;
providing an agent into the fluid-tight intermediary space;
inflating the fluid-tight intermediary space with the agent to cause the first balloon to conform to a shape of the uterine cavity; and
exhausting the agent through the at least one rupture valve and out of the second balloon.

US Pat. No. 11,065,149

PORTABLE THERAPEUTIC SYSTEM USING HOT OR COLD TEMPERATURE


4. A heating or cooling pad for applying hot or cold temperature to an area of a body in need of treatment or therapy using hot or cold temperature, said pad comprising a housing having an upper housing portion and a lower housing, wherein the upper housing portion and lower housing portion form a chamber bounding a temperature-conductive or temperature-retentive gel packet, wherein the lower housing portion is configured to expose a skin-contacting face of the temperature-conductive or temperature-retentive gel packet for contacting the skin of the user and the upper housing portion is an outer cover having an entry port, and a receiving conduit having a distal portion extending within the chamber and a proximal portion extending through the entry port, the receiving conduit further comprising a plurality of exit ports on its distal portion and positioned proximate to the temperature-conductive or temperature-retentive gel packet allowing for delivery and dispersal of a heating or cooling medium to the temperature-conductive or temperature-retentive gel packet while the pad is in use on the body so that the temperature-conductive or temperature-retentive gel packet is cooled or heated at the applied area of the body without requiring removal of the pad or without requiring continuous circulation of the medium from the source to the pad during use.

US Pat. No. 11,065,148

HEAT EXCHANGER CAP

PAXMAN COOLERS LIMITED, ...


1. A heat exchanger cap configured to conform to a human head, the cap comprising:a first element for covering one side of the head;
a second element for covering the other side of the head; and
an intermediate joining element joined to and which spaces apart the first element and second element, the intermediate joining element having a length measured between a front and a back and also having a width, the width being substantially constant along the length;
the intermediate joining element extending outward beyond two sides of the first and second elements;
each of the elements defining a single passageway for the passage of fluid through the cap;
each of the elements being provided with a flow interface in the region where the elements are joined;
the flow interface defining an inlet for the passage of fluid into the passageway of one of the elements, and an outlet for the passage of the fluid from the passageway out of the same element; and
in at least the first element and the second element the single passageway defines flow regions on both sides of a junction line with each of the flow regions extending along just a portion of the cap with the portions located on opposing sides of the junction line, the passageway in each of the flow regions of the first and second elements comprising a boustrophedonic route aligned in a direction from back to front of the first and second elements.

US Pat. No. 11,065,147

DEVICES, SYSTEMS, AND METHODS FOR PRE-HEATING FLUID TO BE INTRODUCED INTO A PATIENT DURING A SURGICAL PROCEDURE

Covidien LP, Mansfield, ...


1. A surgical system, comprising:a fluid source including a fluid inflow tube;
a fluid delivery device coupled to the fluid inflow tube and configured to deliver fluid from the fluid source into a patient;
a surgical instrument;
a control box coupled to the surgical instrument, the control box including: at least one waste heat-generating electronic component; and
a heat pipe assembly disposed in thermal communication with the at least one waste heat-generating electronic component,
wherein the fluid inflow tube is disposed in thermal communication with the heat pipe assembly of the control box such that the heat pipe assembly conducts heat away from the at least one waste heat-generating electronic component and heats fluid flowing through the fluid inflow tube.

US Pat. No. 11,065,146

SYSTEMS AND METHODS FOR PERMANENT FEMALE CONTRACEPTION

Meditrina, Inc., San Jos...


1. A method for occluding a fallopian tube using a system including a delivery catheter and implant, comprising:advancing the delivery catheter to thereby position the implant in a site in the fallopian tube;
activating an energy source to deliver energy through the system to the implant to ablate fallopian tube tissue at the site using the implant;
actuating the system to cause additional trauma that results in a wound healing response at the site that produces an adhesion of walls of the fallopian tube; and
decoupling the implant from the delivery catheter to permit withdrawing the catheter from both the implant and the fallopian tube.

US Pat. No. 11,065,145

SPHINCTER-TYPE INTESTINAL VALVE


1. A sphincter-type intestinal valve for regulating intestinal transit, comprising:a biocompatible tubular intestinal casing having an adjustable electromagnetic valve arranged on said casing;
a mechanical intestinal valve arranged at a free end of said biocompatible tubular intestinal casing;
a check valve arranged at a free end of said mechanical intestinal valve, which is coupled with a free end of the intestinal mechanical valve, and in which a free end of the check valve is configured to be in contact with the outside; and
a sealed rotary occluder which seals the free end of the check valve.

US Pat. No. 11,065,144

OSTOMY POUCH WITH NIGHT DRAINAGE ADAPTER

Hollister Incorporated, ...


1. An ostomy pouch comprising:a collection pouch having a first side wall and a second side wall connected to one another along a periphery, the collection pouch having a collection cavity defined between the first and second side walls;
an outlet connected to and extending from the collection pouch, the outlet defining an internal passageway connected to the collection cavity, the outlet having a coupling element, wherein the coupling element includes a pouch sealing band configured to sealingly engage a drainage adapter; and
the drainage adapter configured to engage the coupling element so as to be coupled to the outlet, wherein the drainage adapter includes a first groove and a second groove, wherein the first groove is configured to receive the pouch sealing band, wherein the pouch sealing band is urged into and held in sealing contact against the drainage adapter in the first groove under a spring force of a material from which the pouch sealing band is formed; and
a locking element (54) configured to fit around the drainage adapter (28), wherein the second groove (44) is configured to receive the locking element,
wherein the outlet is foldable to a closed condition to close the collection pouch and unfoldable to an open condition to drain the collection pouch.

US Pat. No. 11,065,143

WHEELCHAIR BODY HARNESS


1. A wheelchair body harness system comprising:a vest portion with right and left flaps, said vest portion having a zipper on an anterior side of the vest portion, a plurality of side and shoulder straps and associated buckle members attached to said straps, and a hook and loop fasteners section on a posterior side of the vest portion;
a seat portion created from a seat strap to be located between a user's legs, said seat strap having first and second buckle members corresponding to third and fourth buckle members located on respective sides of an interior waist area of the vest portion; and
a plurality of corresponding side and shoulder straps and buckle members attached to a wheelchair to be secured to the plurality of side and shoulder straps and buckle members of the vest portion and a hook and loop fasteners back attached to a wheelchair to adhere to said hook and loop fasteners section.

US Pat. No. 11,065,142

ORTHOPEDIC DEVICES AND SYSTEMS INTEGRATED WITH CONTROLLING DEVICES

Quazar EKB LLC, Alpharet...


1. A support and/or treatment system, comprising:an orthopedic device adapted to be worn by a patient, wherein the orthopedic device comprises a joint support brace or sleeve, for a knee or an elbow;
a control unit including a processor integrated with the orthopedic device;
a telemedicine control device remote from the orthopedic device and connected to the control unit over a network;
an adjustment mechanism integrated with the orthopedic device, wherein the control unit is in controlling combination with the adjustment mechanism, and the adjustment mechanism comprises a compression subsystem integrated with the orthopedic device and having variable tension controllable by the telemedicine control device via the control unit, the compression subsystem comprises: a rotating bar or rod and a motor configured to rotate the rotating bar or rod to adjust a compression or tension in the orthopedic device, and a plurality of straps each connected at a first end to the rotating bar or rod and fixed at a second end to the brace or sleeve, wherein rotation of the rotating bar or rod tightens or loosens the plurality of straps to adjust compression of the brace or sleeve about an internal cavity of the brace or sleeve;
a sensor subsystem integrated with the orthopedic device and in communication with the control unit, wherein the compression or tension is automatically monitored by the sensor subsystem and automatically adjustable by the control unit, and wherein the sensor subsystem comprises a first flexible ring integrated with the orthopedic device, encircling the internal cavity of the brace or sleeve, and with at least one sensor adapted to measure swelling in a body part within the first flexible ring and the orthopedic device; and
wherein the telemedicine control device is accessible by a remotely located telemedicine healthcare provider to receive metrics from the control unit and for control and adjustment of the adjustment mechanism and the orthopedic device throughout treatment of the patient by the telemedicine healthcare provider via the orthopedic device.

US Pat. No. 11,065,141

RECONSTRAINMENT BAND WITH REDUCED REMOVAL INTERFERENCE

BOSTON SCIENTIFIC SCIMED,...


1. A reconstrainment band for use with a stent delivery device, the reconstrainment band comprising:a hollow generally tubular shaped band having proximal and distal ends and a longitudinal axis extending therebetween, the band having an exterior surface for engaging a stent and an interior surface for engaging a delivery tube,
the exterior surface of the band having at least one fin projecting therefrom, each fin having a length extending along the longitudinal axis of the band and a width extending transverse to the length, wherein the length is greater than the width, the fin including first and second opposing obtusely shaped surfaces angled relative to the longitudinal axis, the first obtusely shaped surface facing the proximal end and the second obtusely shaped surface facing the distal end, each obtusely shaped surface having rounded side and top edges extending along the length of the fin, and a radially outermost extent of the fin being a convexly curved surface extending between the rounded top edges of the first and second obtusely shaped surfaces and along the length of the fin.

US Pat. No. 11,065,140

ROTATABLE STENT DELIVERY APPARATUS TO COVER ACCESS SITE

Covidien LP, Mansfield, ...


1. A method for delivering a stent into a body lumen, comprising:delivering a stent delivery system distally through an access site in a wall of the body lumen, wherein the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and wherein the stent is releasably coupled with the first portion of the positioning member;
withdrawing an outer constrainment member from the stent to deploy a proximal portion of the stent to an expanded configuration and maintain a distal portion of the stent in a constrained configuration within the body lumen;
rotating, about a longitudinal axis of the stent, the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site after deploying the proximal portion of the stent to the expanded configuration and maintaining the distal portion of the stent in the constrained configuration;
removing a primary constrainment member from the stent to deploy the distal portion of the stent within the body lumen after withdrawing the positioning member back through the access site; and
covering the access site with the proximal portion of the stent upon fully deploying the proximal portion and the distal portion from the outer constrainment member.

US Pat. No. 11,065,139

APPARATUSES FOR STENT DELIVERY AND POSITIONING TO COVER AN ACCESS SITE

Covidien LP, Mansfield, ...


1. A stent delivery device, comprising:a stent configured to be delivered into a body lumen;
a tubular member being configured to advance through an access site in a wall of the body lumen, wherein the stent is disposed onto the tubular member such that the tubular member is inside the stent along a distal portion of the stent and outside of the stent along a proximal portion of the stent;
a suture tied around the stent configured to releasably couple the stent to the tubular member; and
an outer sheath at least partially disposed around the suture tied around the stent, the stent, and the tubular member, wherein the tubular member and the suture tied around the stent are configured to reposition the stent within the body lumen after removal of the outer sheath such that at least a portion of the stent covers the access site after withdrawal of the tubular member, the suture tied around the stent, and the outer sheath from the body lumen through the access site.

US Pat. No. 11,065,138

HEART VALVE PROSTHESIS DELIVERY SYSTEM AND METHOD FOR DELIVERY OF HEART VALVE PROSTHESIS WITH INTRODUCER SHEATH AND LOADING SYSTEM

JenaValve Technology, Inc...


1. A catheter system for deployment of a heart valve prosthesis, the catheter system comprising:a first retaining sleeve configured to house a first portion of the heart valve prosthesis in a first compressed state;
a second retaining sleeve disposed distal to the first retaining sleeve and configured to house a second portion of the heart valve prosthesis in a second compressed state;
a catheter shaft extending between and coupled to the first retaining sleeve and the second retaining sleeve; and
a stent holder configured to be disposed within the first retaining sleeve to releasably engage the heart valve prosthesis in a first position and to move relative to the first retaining sleeve to a second position to deploy the heart valve prosthesis,
wherein the second retaining sleeve is axially movable with respect to the catheter shaft, the first retaining sleeve is axially fixated to the catheter shaft, the stent holder is axially movable with respect to the catheter shaft, and the first retaining sleeve and the second retaining sleeve are configured to house the heart valve prosthesis such that an exposed portion of the heart valve prosthesis extends between the first retaining sleeve and the second retaining sleeve.

US Pat. No. 11,065,137

STENT DELIVERY SYSTEMS WITH A REDUCED PROFILE


1. A medical device, comprising:an inner shaft having a stent receiving region;
a bumper shaft disposed about the inner shaft;
wherein the bumper shaft has a body section and a distal section with an outer diameter that is smaller than an outer diameter of the body section; and
a deployment sheath slidably disposed about the inner shaft, the deployment sheath having a handle coupled thereto, a body region designed to be disposed within a patient during use and a distal stent covering region designed to cover the stent receiving region, the distal stent covering region having a substantially constant outer diameter that is smaller than all other portions of the deployment sheath,
wherein the body region extends from the handle to a position adjacent to the distal stent covering region,
wherein a first transition is disposed between the body region and the distal stent covering region of the deployment sheath, wherein a second transition is disposed between the body section and the distal section of the bumper shaft, wherein a stent having a stent length is disposed along the inner shaft, and wherein the first transition and the second transition are separated by a distance when the deployment sheath is extended distally over the stent.

US Pat. No. 11,065,136

VASCULAR EXPANDABLE DEVICES

COVIDIEN LP, Mansfield, ...


1. An expandable device implantable across an aneurysm in a blood vessel of a patient, the expandable device comprising:a generally tubular structure formed of a plurality of braided metallic strands, the tubular structure having a proximal end, a distal end, and a length between the proximal end and the distal end;
a compressed state in which the expandable device has a compressed state diameter of 0.027 inches or less;
an expanded state in which the expandable device has an expanded state diameter corresponding to the expandable device, the expanded state diameter being 1.75 mm or more,
wherein each of the plurality of metallic strands has an oxide layer having a thickness of about 400 angstroms or less, wherein the oxide layer (a) is essentially free of titanium, and (b) includes cobalt and/or chromium, wherein the oxide layer is formed at least in part by a heat treatment and
wherein the tubular structure is configured to self-expand from the compressed state to the expanded state.

US Pat. No. 11,065,135

THIN, NARROW TUBE AND DRAWING APPARATUS AND DRAWING METHOD FOR MANUFACTURING THE SAME

NATIONAL INSTITUTE OF ADV...


1. A drawing system for manufacturing a component of a biodegradable medical device, the system comprising: a round tube made of a magnesium alloy (Mg) having a hexagonal crystal structure, andthe magnesium alloy forming the round tube, viewed in a round tube axis direction of the round tube, has hexagonal basal planes (0001) of crystals of magnesium alloy oriented at a predetermined inclination angle with respect to a circumferential direction perpendicular to a radial direction of the round tube, and
a drawing apparatus comprising at least:first means including a part (?) which surrounds the round tube while being in contact with the round tube in a circumferential direction to reduce a diameter of the round tube; and
cylindrical second means which is disposed to oppose a minimum inner diameter portion of the part (?) and of which a side surface supports the round tube,
wherein a center axis of the minimum inner diameter portion and a center axis of the second means coincide with a drawing direction of the round tube, and
the first means and the second means are separated from each other over entire circumferences by a thickness of the round tube,
wherein the second means protrudes from the minimum inner diameter portion in the drawing direction of the round tube and permits the round tube to slide thereon as the drawing proceeds, and the round tube and the second means are configured to be separated from each other by sliding on each other,
wherein the first means comprises a die or rolls, and
wherein the second means is a mandrel.


US Pat. No. 11,065,134

PROSTHESIS LINER

OTTO BOCK HEALTHCARE GMBH...


1. A prosthesis liner configured to fit over a stump of a limb, the liner comprising:a main body comprising:an inner face directed towards a skin surface of the stump;
an outer face directed away from the stump;
a proximal access opening;
a closed distal end portion;
a side wall extending from the access opening to the closed distal end portion;

at least one sealing lip at least partially embedded in the main body by casting and protruding radially outwards from an outer face of the main body and toward the access opening, the at least one sealing lip having opposed proximal and distal surfaces that each curve away from the liner body, and a contour of the sealing lip extends from an outer sealing edge of the at least one sealing lip in a distal direction to the liner body;
wherein an angle of curvature of the at least one sealing lip measured between a longitudinal axis of the liner and the sealing lip, or a tangential plane of the sealing lip, is increasing from the liner body to the outer sealing edge, the outer sealing edge being spaced away from the main body.

US Pat. No. 11,065,133

PROSTHESIS THAT CAN BE ACTUATED BY EXTERNAL FORCE


1. A prosthesis comprising:a prosthesis socket;
an exoprosthesis with a joint; and
at least one prosthesis motor that is activatable by a prosthesis control device, the joint of the exoprosthesis being movable by the prosthesis motor under control of the prosthesis control device so as to replicate a gripping process,
wherein the prosthesis control device includes a housing, a microcontroller arranged in the housing, and a display device for displaying parameters of the gripping process,
the prosthesis control device also includes an input device by which a desired gripping force and/or gripping time is actively settable by a prosthesis wearer directly on the prosthesis control device before performance of the gripping process, and is re-adjustable during the gripping process by the prosthesis wearer,
the desired gripping force and/or gripping time are displayable by the display device before performance of the gripping process, and
no electromyography signals are recorded or evaluated by the prosthesis control device.

US Pat. No. 11,065,132

METHOD OF EXPANDING A SPACE BETWEEN OPPOSING TISSUE SURFACES

SPINE WAVE, INC., Shelto...


1. A method of expanding a space between two opposing tissue surfaces of a patient, comprising the steps of:placing an expansion instrument into said space between said two opposing tissue surfaces;
expanding said space by operation of said instrument to thereby distract said opposing tissue surfaces by sequentially creating a plurality of individually expanded spaces;
introducing a plurality of inserts one at a time sequentially into a respective individually expanded space, each insert being introduced at least partially into said respective individually expanded space independently of the expansion of said space while said expansion instrument is in place to thereby tentatively hold said distracted opposing tissue surfaces; and
removing said expansion instrument while leaving said inserts in said expanded space to support said distracted opposing tissue surfaces.

US Pat. No. 11,065,131

INTERBODY FUSION SYSTEM AND METHODS

Spineology Inc., St. Pau...


1. A portal system for intervertebral surgical fusion procedures, comprising:a longitudinally elongated hollow body comprising a first wall, a second wall opposing the first, a third wall spanning from a first edge of the first wall to a first edge of the second wall and a fourth longitudinal side being located opposite the third wall and spanning between the second edge of the first wall and the second edge of the second wall; and
a channel defined longitudinally through at least one of the first, second and third walls,
wherein the fourth side defines an opening that extends from a proximal end of the longitudinally elongated hollow body towards a distal end of the longitudinally elongated hollow body for at least a majority of a longitudinal length of the longitudinally elongated hollow body, and
wherein the fourth side further comprises a solid fourth wall portion located adjacent to the distal end, opposite the third wall, and spanning between a second edge of the first wall and a second edge of the second wall.

US Pat. No. 11,065,130

EXPANDABLE SPINAL IMPLANT SYSTEM AND METHOD OF USING SAME

WARSAW ORTHOPEDIC, INC., ...


1. An expandable spinal implant deployable between a collapsed position and an expanded position in a disc space between upper and lower vertebral bodies, the expandable spinal implant comprising:a frame comprising an upper surface and a lower surface, a frame proximal end having a proximal wall, and a frame distal end having a distal wall, the frame proximal end having a proximal end width, and the frame defining a central longitudinal axis, a distal aperture being defined in the distal wall;
a plug movably disposed in the distal aperture and configured for movement from a position intermediate a proximal end and a distal end of the implant toward the distal end of the implant, the plug including a head portion including at least a first lateral post portion and at least a second lateral post portion;
a first endplate portion pivotally engaged with the frame and configured to expand outward from the frame when the plug is moved in a distal direction, the first endplate portion including an upper surface, a first endplate portion proximal end, a first endplate portion distal end, a first endplate portion first lateral surface extending between the first endplate portion proximal end and the first endplate portion distal end, an opposing first endplate portion second lateral surface extending between the first endplate portion proximal end and the first endplate portion distal end, and at least a first channel formed in the first endplate portion adjacent the first endplate portion first lateral surface, the at least a first channel being configured to receive the at least a first lateral post portion;
a first distal end portion extending outwardly from the first endplate portion including a first side surface, a second side surface, and a first tip portion, the first side surface of the first distal end portion extending from the first tip portion to the first endplate portion first lateral surface, and the second side surface of the first distal end portion extending from the first tip portion to the first endplate portion second lateral surface;
a second endplate portion pivotally engaged with the frame and configured to expand outward from the frame when the plug is moved in the distal direction, the second endplate portion including a lower surface, a second endplate portion proximal end, a second endplate portion distal end, a second endplate portion first lateral surface extending between the second endplate portion proximal end and the second endplate portion distal end, and an opposing second endplate portion second lateral surface extending between the second endplate portion proximal end and the second endplate portion distal end, and at least a second channel formed in the second endplate portion through the second endplate portion first lateral surface, the at least a second channel being configured to receive the at least a second lateral post portion;
a second distal end portion extending outwardly from the second endplate portion including a first side surface, a second side surface, and a second tip portion, the first side surface of the second distal end portion extending from the second tip portion to the second endplate portion first lateral surface, and the second side surface of the second distal end portion extending from the second tip portion to the second endplate portion second lateral surface;
wherein the at least a first channel extends in a first plane that is transverse to a mid-longitudinal axis of the first endplate portion, the at least a second channel extends in a second plane that is transverse to a mid-longitudinal axis of the second endplate portion, and movement of the plug toward the distal end of the implant, and corresponding interaction of the at least a first lateral post portion in the at least a first channel causes the first endplate portion and the first distal end portion to move away from the frame and interaction of the at least a second lateral post portion in the at least a second channel causes the second endplate portion and the second distal end portion to move away from the frame to move the implant from the collapsed position to the expanded position; and
wherein the first distal end portion includes a mid-longitudinal axis that is transverse to the mid-longitudinal axis of the first endplate portion, and the second distal end portion includes a mid-longitudinal axis that is transverse to the mid-longitudinal axis of the second endplate portion.

US Pat. No. 11,065,129

EXPANDABLE INTERVERTEBRAL FUSION DEVICE

Zimmer Biomet Spine, Inc....


1. An expandable intervertebral fusion device comprising:a core having a first plurality of superiorly facing inclined plane surfaces and a first plurality of inferiorly facing inclined plane surfaces;
a superior endplate for contacting a first vertebral body, the superior endplate including a second plurality of inferiorly facing inclined plane surfaces for slidably engaging the first plurality of superiorly facing inclined plane surfaces of the core; and
an inferior endplate for contacting a second vertebral body, the inferior endplate including a second plurality of superiorly facing inclined plane surfaces for slidably engaging the first plurality of inferiorly facing inclined plane surfaces of the core;
wherein linear translation of the core relative to the superior endplate and the inferior endplate causes the fusion device to transition from a first collapsed state to a second expanded parallel state to a third expanded lordotic state, and
wherein the expandable intervertebral fusion device includes a first length in the first collapsed state, a second length in the second expanded parallel state and a third length in the third expanded lordotic state, wherein the first length is longer than the second length which is longer than the third length, and wherein each of the first length, the second length, and the third length is measured along the longitudinal axis from the proximal end of the central core to a distal tip of each of the superior endplate and the inferior endplate.

US Pat. No. 11,065,128

INTERVERTEBRAL IMPLANTS AND RELATED METHODS OF USE

Globus Medical, Inc., Au...


1. An intervertebral spacer system, comprising:an intervertebral spacer comprising a spacer portion and a plate portion, the plate portion including at least one bore configured and dimensioned to receive a vertebral anchor;
the vertebral anchor comprising:a head portion that is at least partially spherical;
an elongate shank extending from the head portion; and
an elongate fin extending from the head portion and along a surface of the elongate shank, the elongate shank and the elongate fin disposed generally perpendicular to each other,
wherein the elongate shank is curvilinear,
wherein the elongate fin extends from the head portion to an apex of the elongate shank, the apex being defined as the most distal point of the vertebral anchor such that the most distal point of both the elongate fin and the elongate shank meet at the apex, wherein the apex is configured to be a point that first impacts bone by the vertebral anchor.


US Pat. No. 11,065,127

DUAL-LEAD THREAD DRIVE SCREW FOR A LATERAL EXPANDING COAXIAL SPINAL IMPLANT

Hammill Medical LLC, Pal...


1. A dual-lead thread drive screw for a lateral expanding coaxial spinal implant system comprising:a substantially rectangular bottom endplate having first and second vertical sidewalls, each of said sidewall including a front slot and rear slot angled away from a front end of said bottom endplate;
a substantially rectangular top endplate having first and second vertical sidewalls, each of said sidewall including a front slot and rear slot angled away from a rear end of said top endplate;
a frame positionable between said top endplate and said bottom endplate extending around an outer perimeter of said spinal implant, said frame having a front end and a rear end, said front end of said frame including an end cap, said frame having a left arm and a right arm extending between said rear end to said end cap on said front end, said frame rear end including an aperture and a cavity for receiving an adjustment nut;
a drive screw rotatably formed from a shank insertable into said frame aperture, said drive screw having dual-load threads formed along a first portion and right-hand threads formed along a second portion, said drive screw having a center section positioned between said first and second portions;
a first actuator threadably attached to said first portion of said drive screw, said first actuator including a forward pin and a rearward pin operatively associated with said slots formed in said first vertical sidewalls of said top and bottom endplates, said first actuator having a left-hand threaded boss for threadably attaching said drive screw;
a second actuator threadably attached to said second portion of said drive screw, said second actuator including a forward pin and a rearward pin operatively associated with said slots formed in said second vertical sidewalls of said top and bottom endplates;
an adjustment nut threadably attached to said second portion of said drive screw, said adjustment nut positioned in said cavity of said frame;
whereby rotation of said adjustment nut moves said first and second actuators in unison, wherein said pins engage said slots to cause equal separation of said bottom and top endplates; and
whereby rotation of said drive screw causes said first and second actuators to cause lateral rotation of said bottom and top endplate.

US Pat. No. 11,065,126

INTERBODY IMPLANTS AND OPTIMIZATION FEATURES THEREOF

Stryker European Operatio...


1. A spinal interbody device (IBD) comprising:a solid wall at least partially defining a boundary of the IBD; and
a porous body connected to the solid wall and having a plurality of sections forming at least a portion of both a superior and inferior bone interface side of the IBD, wherein each section of the porous body has a different porosity than an adjacent section such that the porosities increase toward a center of the IBD.

US Pat. No. 11,065,125

TOTAL SHOULDER PROSTHESIS HAVING INSET GLENOID IMPLANT CONVERTIBLE FROM ANATOMIC TO REVERSE

Shoulder Innovations, Inc...


1. A method of converting an anatomic to a reverse shoulder prosthesis, comprising:identifying a patient with an anatomic glenoid articular implant within a glenoid cavity, the anatomic articular implant comprising a medial surface mated with the glenoid cavity, a central peg extending medially from the medial surface, a lateral surface articulating with a humeral component; and a central component between the lateral surface and the medial surface, the central component having an outer diameter reversibly attached to a snap ring and a fixation ring, the snap ring and the fixation ring at least partially implanted within the glenoid cavity;
inserting a implant removal tool through the lateral articulating surface of the anatomic glenoid articular implant sufficient to collapse the snap ring;
removing the anatomic glenoid articular implant while leaving the fixation ring in place within the glenoid cavity; and
inserting a reverse shoulder implant into the glenoid cavity sufficient to actuate the snap ring such that the reverse shoulder implanted is reversibly fixed to the fixation ring.

US Pat. No. 11,065,124

VARIABLE THICKNESS FEMORAL AUGMENTS

Howmedica Osteonics Corp....


1. A kit for augmenting a resected femur in a revision total knee arthroplasty, comprising:a first set of femoral augments each having condylar portions and a flange portion connecting the condylar portions, the condylar portions and flange portion defining outer and inner sides of the respective femoral augment, the outer side and inner side each having a plurality of intersecting planar surfaces wherein the intersecting planar surfaces of the outer side includes anterior, posterior, and distal surfaces, and the inner side includes anterior, posterior, and distal surfaces, wherein an anterior thickness of each of the femoral augments in the first set of femoral augments is defined between the anterior surfaces of the outer and inner sides, a posterior thickness of each of the femoral augments is defined between the posterior surfaces of the outer and inner sides, and a distal thickness is defined between the distal surfaces of the outer and inner sides, wherein the distal thickness is different between each femoral augment in the first set and the anterior and posterior thicknesses are constant.

US Pat. No. 11,065,122

TECHNIQUES FOR USE WITH PROSTHETIC VALVE LEAFLETS

CARDIOVALVE LTD., Or Yeh...


1. A method for determining a flexibility of a prosthetic heart valve leaflet, the method comprising:placing the leaflet across a bar, and positioning the bar such that the leaflet drapes over the bar and blocks a beam of light emitted by a light source;
while the leaflet remains draped over the bar, elevating the bar at least until the leaflet stops blocking the beam; and
identifying an elevation, of the bar from the beam, at which the leaflet stopped blocking the beam.

US Pat. No. 11,065,121

INTRODUCER SYSTEMS, DEVICES AND METHODS FOR HEART VALVE REDUCTIONS

BOSTON SCIENTIFIC SCIMED,...


1. An introducer catheter device comprising:a handle; and
an elongate shaft coupled to the handle and extending therefrom, the shaft defining a lumen therethrough and a longitudinal axis, the shaft defining a first aperture in connection with the lumen, and comprising a movable deployment element configured for deploying an ancillary device from the first aperture at an angle relative to the longitudinal axis;
wherein the shaft comprises a weeping balloon encapsulating a shaft portion comprising a digital camera.

US Pat. No. 11,065,120

METHOD AND APPARATUS FOR CARDIAC PROCEDURES

University of Maryland, B...


1. A method for using locking sutures to approximate anchor implants attached to targeted tissue, the method comprising:attaching two or more cords to targeted tissue, individual cords including a distal anchor implant and a suture extending proximally from the distal anchor implant;
intertwining proximal end portions of the two or more sutures with a knot of a locking suture, the locking suture including a tether portion extending from the knot and configured to be manipulated to transition the knot from a delivery configuration to a deployed configuration;
positioning the knot of the locking suture relative to the two or more sutures by sliding the knot along the two or more sutures to approximate portions of the targeted tissue; and
transitioning the knot from the delivery configuration to the deployed configuration to lock the locking suture by creating a confined tortuous path for the two or more sutures through the knot of the locking suture.

US Pat. No. 11,065,119

LONG ARM VALVE REPAIR CLIP

Evalve, Inc., Santa Clar...


1. A fixation device for engaging tissue comprising:a pair of fixation elements, each fixation element having a first end and a second end opposite the first end, the first ends being moveable between a closed position and an open position;
a pair of gripping elements, each gripping element moveable with a respective fixation element and disposed in opposition to at least a portion of the respective fixation element to capture tissue therebetween; and
a central portion operatively connected to each gripping element at a respective central portion-gripping element interface, the central portion having a distal end, the central portion having a width “W1” proximate the distal end, each gripping element having a free end opposite its respective central portion-gripping element interface and a length “L1” defined between the respective central portion-gripping element interface and the free end, wherein the length L1 is at least about three times the width W1,
wherein each gripping element includes at least one gripper line attachment location disposed along the length L1 of the gripping element with each attachment location spaced from the free end of the gripping element.

US Pat. No. 11,065,118

CARDIAC VALVE COMMISSURE BRACE

The Medical Research, Inf...


1. A brace for mounting to an annulus of a cardiac valve, the brace comprising:first and second bottom gripping wings for gripping the annulus;
first and second top gripping wings for gripping the annulus; and
a support bridge that connects the top wings to the bottom wings;
wherein the brace is formed from a shape memory material and the first top and the first bottom gripping wings, or the first and the second top gripping wings, are integral parts of a same first strip of the shape memory material separated by a bridge portion of the first strip and wherein the brace is deformable from a delivery configuration to a deployed configuration and in the delivery configuration the top wings are oriented substantially back to back along an axis and the bottom wings are oriented substantially back to back along the same axis, and in the deployed configuration the brace assumes an H-like shape the first and second top gripping wings are adjacent, extend away from the support bridge in opposite directions to lie along adjacent portions of the annulus the first and second bottom gripping wings are adjacent, extend away from the support bridge in opposite directions to lie along adjacent portions of the annulus, and the first top and bottom gripping wings face each other to grip the annulus between them and the second top and bottom gripping wings face each other to grip the annulus between them.

US Pat. No. 11,065,117

AXISYMMETRIC ADJUSTABLE DEVICE FOR TREATING MITRAL REGURGITATION

Edwards Lifesciences Corp...


1. A system for treating a heart valve, comprising:a delivery catheter;
a prosthetic device comprising:an anchor member configured to engage heart tissue;
wherein the anchor member is collapsible and expandable;
a prosthetic sealing member that is collapsible and expandable;
wherein the prosthetic sealing member in an expanded configuration comprises an axisymmetrical or elliptical top profile;

wherein the sealing member in the expanded state is adapted to engage native valve leaflets during systole to plug a gap between the native valve leaflets and reduce regurgitation;
wherein the sealing member permits the native valve leaflets to open and close as the heart beats;
wherein the sealing member is configured to be selectively rotated with respect to the anchor member;
a lock configured to selectively lock the sealing member at a selected rotational position with respect to the anchor member.

US Pat. No. 11,065,116

APPARATUS AND METHODS FOR TRANS-SEPTAL RETRIEVAL OF PROSTHETIC HEART VALVES

Tendyne Holdings, Inc., ...


1. A method, comprising:inserting a retrieval assembly through a femoral vein and into a heart of a patient until a distal end portion of the retrieval assembly is disposed in an atrium of the heart, the retrieval assembly including a snare member;
moving the snare member distally out of a lumen of the retrieval assembly and into engagement with an inner frame of a prosthetic heart valve implanted within the heart;
manipulating the retrieval assembly to invert an outer frame of the prosthetic heart valve such that the prosthetic heart valve is collapsed and at least a portion of the prosthetic heart valve is retracted into a lumen of the retrieval assembly.

US Pat. No. 11,065,115

PROSTHETIC HEART VALVE HAVING AN INNER FRAME AND AN OUTER FRAME

Edwards Lifesciences Corp...


1. A prosthetic heart valve, comprising:a radially compressible and expandable, annular metal outer frame defining a lumen, the outer frame having a longitudinal axis that extends from an inflow end of the outer frame to an outflow end of the outer frame, the outer frame comprising a plurality of struts defining a plurality of cells arranged in a plurality of circumferentially extending rows of cells that extend continuously around the outer frame;
a radially compressible and expandable, annular metal inner frame positioned within the lumen of the metal outer frame and extending axially along the longitudinal axis of the outer frame such that an end of the inner frame is positioned axially between the inflow and outflow ends of the outer frame and spaced radially inwardly from an inner surface of the outer frame such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame at the end of the inner frame, wherein the outer frame is coupled to the inner frame, and wherein the inner frame comprises a plurality of commissure posts and a plurality of struts arranged to form a plurality of cells adjacent the commissure posts; and
a plurality of leaflets made of pericardium and disposed within the inner frame, wherein each leaflet has a side portion paired with an adjacent side portion of an adjacent leaflet with each pair of side portions supported by a corresponding commissure post; and
a fabric sleeve disposed radially between the outer frame and the inner frame, wherein the fabric sleeve extends along the inner surface of the outer frame.

US Pat. No. 11,065,114

FRAME FOR PROSTHETIC VALVE

TEL HASHOMER MEDICAL RESE...


1. A method for use with a prosthetic valve that is configured to be deployed within a native atrio-ventricular valve of a heart of a mammalian subject, the native atrio-ventricular valve including a valve annulus, valve leaflets, chords, and papillary muscles, the method comprising:placing a valve frame within the subject's heart, the valve frame including:a valve frame body that is configured to support the prosthetic valve within the native atrio-ventricular valve, and that includes an atrial portion and a ventricular portion, and
at least one arm that is configured to extend from the ventricular portion of the valve frame;

deploying the at least one arm among the chords of the native atrio-ventricular valve;
subsequently, rotating at least a portion of the valve frame, such as to cause the arm to twist the leaflets of the native valve, such that the leaflets of the native valve are placed in overlapping configurations with respect to each other; and
subsequently, causing the frame body of the valve frame to radially expand, such as to trap the leaflets of the native valve in the overlapping configurations with respect to each other.

US Pat. No. 11,065,113

PROSTHETIC HEART VALVE HAVING AN IMPROVED TUBULAR SEAL

Boston Scientific Scimed,...


1. A tubular seal for a prosthetic heart valve comprising:an elastomeric polymer matrix and a woven fabric embedded within the polymer matrix, the woven fabric comprising a plurality of non-elastic fibers retained within an inflow end region of the elastomeric polymer matrix, wherein the woven fabric comprising a non-linear edge embedded within the elastomeric polymer matrix.

US Pat. No. 11,065,112

FRAME WITH INTEGRAL SEWING CUFF FOR PROSTHETIC VALVES


1. A method of making a frame assembly for a prosthetic valve, comprising:coupling a frame defining a tubular shape to a fabric having fabric pores, the fabric defining a fabric frame portion and a sewing cuff portion opposite the fabric frame portion, wherein at least a portion of the fabric frame portion has an elastomer in the fabric pores and the sewing cuff portion of the fabric does not have an elastomer present in the fabric pores; and
coupling a composite material to at least a portion of the fabric frame portion with the fabric frame portion disposed between the frame and the composite material and such that the sewing cuff extends from the frame.

US Pat. No. 11,065,111

SYSTEMS AND MECHANISMS FOR DEPLOYING A DOCKING DEVICE FOR A REPLACEMENT HEART VALVE

Edwards Lifesciences Corp...


1. A delivery device for delivering a docking device to a native valve annulus of a patient's heart, the delivery device comprising:a delivery catheter having a first lumen; and
a pusher tool comprising:a pusher slidably received within the first lumen, the pusher having a distal portion, a proximal portion, and a second lumen extending from the proximal portion to the distal portion, wherein the pusher comprises a helically wound wire;
a locking mechanism fixedly attached to the proximal portion of the pusher; and
a retrieval line extending through the second lumen from the locking mechanism to the docking device to connect the docking device to the pusher tool;
wherein the locking mechanism includes a rotatable member connected to the retrieval line, the rotatable member having a first position that locks the amount of retrieval line that extends from the locking mechanism and a second position that allows the amount of retrieval line that extends from the locking mechanism to be increased or decreased.


US Pat. No. 11,065,110

CALCIFIED ANNULUS MODEL FOR TRANSCATHETER AORTIC VALVE REPLACEMENT

Regents of the University...


1. An implantable device for promoting aortic stenosis, the device comprising a plurality of independent segments, each segment including an elastic core encased in a fabric sheath, wherein the plurality of segments are configured for individual placement within a tract and configured to form an annulus in the tract, and wherein each segment is configured for suturing to a wall of the tract and wherein the plurality of segments are configured to engage with an external surface of an aortic valve replacement device, and wherein the plurality of segments are configured as a continuous ring that encircles the tract and wherein the continuous ring is configured for placement at an annulus of a healthy animal in order to create a stenotic state via a calcified annulus into which the aortic valve replacement device can be placed to correct disease created by the stenotic state.

US Pat. No. 11,065,109

MULTI-PIECE ACCOMMODATING INTRAOCULAR LENSES AND METHODS FOR MAKING AND USING SAME

Shifamed Holdings, LLC, ...


1. A method of implementing an accommodating intraocular lens system, comprising:implanting an accommodating structure into a native eye capsule, wherein the accommodating structure has a first optical component, a second optical component posterior of the first optical component, an inner fluid chamber between the first and second optical components, and an outer fluid reservoir fluidically coupled to the inner fluid chamber;
coupling a fixed lens to the accommodating structure after implanting the accommodating structure in the native eye capsule.

US Pat. No. 11,065,108

INTRAOCULAR LENS HAVING CLOSED-LOOP HAPTIC STRUCTURES

Alcon Inc., Fribourg (CH...


1. An intraocular lens (IOL) comprising:an optic including an optic axis; and
a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure comprising a closed loop extending substantially along a plane perpendicular to the optic axis from first and second attachment points to the frame, the closed loop comprising:a first hinge including a first section, a second section and a first connecting section between the first section and the second section, the first section having a first component extending in a first angular direction, the second section having a second component extending in a second angular direction, wherein the second angular direction is opposite to the first angular direction; and
a second hinge including a third section, a fourth section and a second connecting section between the third section and the fourth section, the third section having a third component extending in the second angular direction, the fourth section having a fourth component in the first angular direction, wherein the second section is connected to the fourth section to form the closed loop;

wherein the first connecting section and the second connecting section are configured to compress such that the first section and the second section are brought closer together and the third section and the fourth section are brought closer together while the first section, the second section, the third section, and the fourth section remain substantially in the plane perpendicular to the optic axis during compression of the closed-loop haptic structure;
wherein the plane perpendicular to the optic axis of the closed loop is a first central plane substantially perpendicular to the optic axis, wherein the optic has a second central plane substantially perpendicular to the optic axis, and wherein the second central plane is located posterior to the first central plane.

US Pat. No. 11,065,107

ACCOMMODATING INTRAOCULAR LENS DEVICE

LensGen, Inc., Irvine, C...


1. An accommodating intraocular lens device comprising:a base assembly comprising a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity, wherein the haptic comprising an outer periphery, an inner surface and a height between a first edge and a second edge; and
a power lens configured to fit within the central cavity, the power lens comprising a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid;
wherein the first side of the power lens is configured to be inserted into the eye separately from the base assembly and configured to be positioned within the cavity after being inserted into the eye at a predetermined distance from the first edge of the haptic.

US Pat. No. 11,065,106

TISSUE HOLDING APPARATUS


1. A tissue holding apparatus configured for implantation of a membrane section into a recipient's eye through an incision in said recipient's eye, the tissue holding apparatus comprising:a) a flexible, curved membrane support configured to bear said membrane section where said membrane section is folded over said flexible curved membrane support; and
b) a curved elastomeric holder having a generally C-shaped cross-section, and configured to be peripherally mounted around said membrane section folded over said flexible, curved membrane support to secure said membrane section to said flexible curved membrane support, wherein said flexible, curved membrane support, said membrane section and said curved elastomeric holder together form a combined structure configured to be temporarily curled upon itself for insertion through the incision into the recipient's eye.

US Pat. No. 11,065,105

REINFORCED BIOLOGICAL CONSTRUCT AND METHOD OF REINFORCING BIOLOGICAL CONSTRUCT

ARTHREX, INC., Naples, F...


1. An assembly, comprising:a folded tendon graft including a first end portion and a second end portion that are stitched together by a suture to form a loop,
wherein the first end portion and the second end portion are part of a single tendon strand;
a first button and loop construct connected to the folded tendon graft;
a second button and loop construct connected to the folded tendon graft; and
a suture tape inserted through at least a portion of the folded tendon graft.

US Pat. No. 11,065,104

TENODESIS ANCHORING SYSTEMS AND TOOLS

Medos International Sarl,...


1. A bone anchor inserter tool, comprising:an outer shaft having proximal and distal ends and an inner lumen extending at least partially therethrough, the distal end having first and second prongs extending distally therefrom; and
an inner shaft extending through the inner lumen of the outer shaft, at least a portion of the inner shaft being non-rotatably and freely slidably coupled to the outer shaft, the inner shaft having a distal end with a distally-extending central protrusion and at least first and second distally-extending side protrusions positioned on opposite sides of the central protrusion.

US Pat. No. 11,065,103

METHOD AND APPARATUS FOR FIXATION OF AN ACL GRAFT

Biomet Sports Medicine, L...


1. A method of placing an ACL grail in a patient, comprising:anchoring an ACL graft to a femur of a patient with a first graft strand; a second graft strand, a third grail strand, and a fourth graft strand of the ACL graft extending out of the femur and through an adjacent tibial tunnel in a tibia of the patient so that the first graft strand, the second graft strand, the third graft strand, and the fourth graft strand of the ACL graft extend out of the tibial tunnel through a first opening in an outer surface of the tibia;
positioning a distal end of a graft strand tensioner against bone around the first opening in the outer surface of the tibia so that a longitudinal axis of the graft strand tensioner is substantially coaxial with a longitudinal axis of the tibial tunnel, the graft strand tensioner including a tensioning arm assembly situated proximally of the distal end of the graft strand tensioner, the tensioning arm assembly movable within the graft strand tensioner away from the distal end of the graft strand tensioner along the longitudinal axis of the graft strand tensioner, the tensioning arm assembly, including a tensioning arm support member that extends transversely across the longitudinal axis of the grail strand tensioner, the tensioning arm assembly further including a first tensioning arm coupled to a first end of the tensioning arm support member and a second tensioning arm coupled to a second end of the tensioning arm support member;
coupling: (i) the first graft strand of the ACL graft to a first end of the first tensioning arm; (ii) the second graft strand of the ACL graft to a second end of the first tensioning arm; (iii) the third grail strand of the ACL graft to a first end of the second tensioning arm; (iv) the fourth graft strand of the ACL graft to a second end of the second tensioning arm; and
moving the tensioning arm assembly away from the distal end of the grail strand tensioner while the distal end of the graft strand tensioner remains against bone around the first opening in the outer surface of the tibia, wherein said moving applies respective tensions to the first graft strand, the second graft strand, the third graft strand, and the fourth graft strand of the ACL graft, and wherein during said moving: (a) the tensioning arm support member rotates within the graft strand tensioner about a support member axis that is substantially perpendicular to the longitudinal axis of the graft strand tensioner; (b) the first tensioning arm rotates about a first tensioning arm axis that is substantially perpendicular to the support member axis; and (c) the second tensioning arm rotates about a second tensioning arm axis that is substantially perpendicular to the support member axis so that following said moving the first graft strand, the second graft strand, the third graft strand, and the fourth graft strand of the ACL graft are substantially equally tensioned.

US Pat. No. 11,065,102

COMPOSITE SCAFFOLD FOR THE REPAIR, RECONSTRUCTION, AND REGENERATION OF SOFT TISSUES

Biorez, Inc., New Haven,...


1. A method of ligament or tendon injury repair with a composite scaffold, the method comprising:A) obtaining a composite scaffold comprising:i) first and second layers spaced apart to define an interior space therebetween and a plurality of spacer elements extending through the interior space and attached to the first and second layers, the plurality of spacer elements comprising a first material; and
ii) a microporous matrix having a multitude of interconnected pores, the microporous matrix disposed within the interior space and comprising a second material, different from the first material, and

B) pre-tensioning the composite scaffold along a length dimension thereof;
C) attaching the composite scaffold to tissue.

US Pat. No. 11,065,101

FAST TORSIONAL ARTIFICIAL MUSCLES FROM TWISTED YARNS OF SHAPE MEMORY MATERIAL

Massachusetts Institute o...


1. A torsional actuator comprising:a yarn, having a first portion and a second portion along a length, comprising a homochirally twisted plurality of homogeneous strands of shape memory material; and
a controller for programmable heating of at least a portion of the yarn,
wherein each homogeneous strand of the first portion is coated with a coating material of higher electrical conductivity than an electrical conductivity of the shape memory material, and
wherein the second portion is configured to preferentially undergo a change in a physical property selected from the group consisting of length, amount of twist, and combinations thereof, relative to the first portion upon application of the programmable heating.

US Pat. No. 11,065,100

VASCULAR REPAIR DEVICES AND METHODS OF USE

Bolton Medical, Inc., Su...


1. A method for treating aortic vascular damage, comprising the steps of:a) delivering a vascular repair device through a blood vessel to an aneurysm site of a patient, the vascular repair device including:i) a main prosthesis having a graft component that includes an external surface and an internal surface, the graft component including a proximal section, a midsection, a distal section, and a planar section between the proximal section and the midsection, the planar section defining openings, and wherein the proximal section defines a proximal open end, the midsection extends distally from a first of the openings of the planar section, and the distal section defines a distal open end, the proximal section defining a proximal lumen and a first major longitudinal axis extending through the center of the proximal lumen;
ii) a first internal prosthesis within the proximal lumen, the first internal prosthesis having a graft component, an external surface and an internal surface, and defining at least in part a first internal lumen, a proximal end located distal to the proximal open end of the main prosthesis, a distal end and a longitudinal axis extending through the first internal lumen, the proximal end and the distal end, and being substantially parallel to the first major longitudinal axis;
iii) a second internal prosthesis within the proximal lumen, the second internal prosthesis having a graft component, an external surface and an internal surface, and defining at least in part a second internal lumen, a proximal end located distal to the proximal end of the first internal prosthesis, a distal end and a longitudinal axis extending through the second internal lumen, the proximal end of the second internal prosthesis and the distal end of the second internal prosthesis, and being substantially parallel to the first major longitudinal axis, and wherein the first and second internal prostheses are on the same side of a plane bisecting the proximal lumen; and
iv) two pairs of sub-prostheses, each of the sub-prostheses of the two pairs of sub-prostheses having a graft component defining a proximal end, a distal end, at least a portion of a sublumen and a longitudinal axis extending through the proximal end and the distal end of each of the respective sub-prostheses and through the sublumens of each of the respective sub-prostheses, the graft component of each of the sub-prostheses having an external surface and an internal surface, wherein a first pair of the sub-prostheses extends distally to a second and a third of the openings defined by the planar section, and the second pair of the subprostheses extends distally to a fourth and fifth of the openings defined by the planar section;

b) directing at least one additional vascular repair device within one of the and second first internal lumen, the at least one additional vascular repair device including a graft component having an external surface and an internal surface;
c) inserting the at least one additional vascular repair device within at least one of the two sub-prostheses of the main prosthesis of the vascular repair device; and
d) inserting the distal end of the at least one additional vascular repair device into at least one branch vessel of the blood vessel, to thereby implant the prosthesis at the aneurysm site of the patient.

US Pat. No. 11,065,099

FLEXIBLE HOLLOW LUMEN COMPOSITE

THE SECANT GROUP, LLC, T...


1. A composite lumen comprising:an extruded tube of a composite comprising a poly(glycerol sebacate) (PGS) matrix mixed with a PGS thermoset filler; and
an overbraid structure overlying an outer surface of the extruded tube.

US Pat. No. 11,065,098

MEDICAL FABRIC

Asahi Kasei Kabushiki Kai...


1. A medical fabric comprising multifilament yarns with a total fineness of 7 to 80 dtex as warp yarns and weft yarns, wherein a single filament fineness of at least one multifilament yarn among the warp yarns and the weft yarns is 0.5 dtex or less, a twist coefficient A of the weft yarns is 50 to 1000, a thickness of the medical fabric is 10 to 90 ?m, a water permeability before and after needle puncture of the medical fabric is 300 cc/min/cm2 or less, a twist coefficient of the warp yarns is 75 to 10000, and a warp/weft twist coefficient ratio B between the warp yarns and the weft yarns is 3.6 to 20.

US Pat. No. 11,065,097

ADVANCED KINK-RESISTANT STENT GRAFT

TriVascular, Inc., Santa...


1. An endovascular stent-graft comprising:a graft; and
an undulating wire connected to the graft, the undulating wire helically wound in a longitudinal direction to form a plurality of undulating windings for a first portion, a second portion, and a third portion between the first and second portions in the longitudinal direction, each of the undulating windings having peaks and valleys,
wherein each of the undulating windings has a peak height defined as a longitudinal distance Y between a peak and an immediately adjacent valley of the undulating windings,
wherein each of the immediately adjacent undulating windings are separated from each other in the longitudinal direction by a valley-to-peak distance defined as a longitudinal distance X between a valley of one of the immediately adjacent undulating windings and a peak of the other immediately adjacent undulating windings,
wherein a ratio X/Y between the valley-to-peak distance X and the peak height Y of the undulating windings of the third portion is greater than the ratio X/Y of the undulating windings of each of the first and second portions, and
wherein the ratio X/Y of the undulating windings of the third portion is a positive value between 0.5 and 5, and the ratio X/Y of the undulating windings for at least one of the first or second portions is a negative value between ?0.1 and ?1 wherein when the undulating windings for at least one of first or the second portions comprise a first winding and a second winding, and a lowest valley of the first winding is lower than a highest peak of the second winding, the negative value results.

US Pat. No. 11,065,096

THROMBOEMBOLIC PROTECTIVE FLOW-DIVERTING, COMMON CAROTID TO EXTERNAL CAROTID INTRAVASCULAR STENT

Loyola University Chicago...


1. A self expanding intravascular stent adapted for use as a thromboembolic flow-diverting device and placement at a bifurcation of a common carotid artery to divert emboli from an origin of an internal carotid artery without obstructing blood flow into the internal carotid artery, the stent having a lumen within and defined by a tubular body having a circular cross-sectional shape, a circumference defined by the circular cross-sectional shape, a proximal end, a distal end, and a length defined by and between the proximal end and the distal end that defines an entire length of the stent, the tubular body comprising:a braided mesh that defines an entirety of the circular cross-sectional shape of the tubular body, an entirety of the circumference of the tubular body, the lumen of the stent, the proximal end and the distal end of the tubular body, an entirety of the length of the tubular body, the entire length of the stent, a pre-deployed diameter of the tubular body, and a post-deployed diameter of the tubular body, the braided mesh being formed of filaments defining interstices through the tubular body and throughout the entirety of the length of the tubular body and the entire length of the stent, the interstices being sufficiently small to provide an emboli-diverting effect wherein embolic material is prevented from passing therethrough but sufficiently large to enable blood to pass therethrough; and
struts arranged as a lattice to create scaffolding along the entirety of the circumference of the tubular body and along the length of the tubular body, the scaffolding generating radial forces greater than radial forces generated by the braided mesh when the tubular body of the stent is expanded to the post-deployed diameter thereof, the struts being spaced apart so as not to interfere with the emboli-diverting effect of the mesh;
wherein in combination the braided mesh and the struts cooperate to create flow dynamics within the lumen of the stent that redirect the embolic material entering the lumen away from the origin of the internal carotid artery and into an external carotid artery rather than being filtered or captured by the braided mesh.

US Pat. No. 11,065,095

SAMPLE CONTAINER WITH PEELABLE SEAL AND ACCESS PORT

Instant Systems, Inc., N...


1. An apparatus, comprising:a flexible container including a first layer coupled to a second layer to define a storage volume within which a tissue specimen can be contained, the first layer characterized by a first stiffness, the second layer characterized by a second stiffness, an edge of the first layer spaced apart from an edge of the second layer to define an opening into the storage volume, the edge of the first layer and the edge of the second layer configured to form a peelable seal that hermetically seals the storage volume such that the first layer can be peeled away from the second layer to expose the storage volume;
a port coupled to the flexible container, the port configured to allow fluid communication between the storage volume and an external volume; and
a support structure configured to support the tissue specimen within the storage volume, the support structure characterized by a third stiffness, the third stiffness greater than the first stiffness and the second stiffness.

US Pat. No. 11,065,094

BIOLOGICAL PROSTHESIS INTENDED FOR THE TREATMENT OF PARASTOMAL HERNIAS

MECCELLIS BIOTECH, La Ro...


1. A biological prosthesis (10) consisting of a first portion (16) extending into a second portion (18), wherein the first portion is in a shape of a truncated cone and the second portion is in a cylindrical shape, wherein the biological prosthesis has a thickness (12) of between 0.5 and 4 mm, wherein the biological prosthesis consists of acellularized tail dermis removed from a part (14) of an animal belonging to a family of pigs, cattle or goats, with the said part (14) of the animal corresponding to a part extending from a first area (16) located at a base of a tail next to a junction of the last sacral vertebrae up to a second area (18) starting at the base of the tail and encompassing a circumference of at least a part of the caudal vertebrae.

US Pat. No. 11,065,093

CATHETER MATING DEVICES

Spinal Singularity, Inc.,...


1. A catheter mating device comprising:(a) a stem having a proximal end and a distal end; wherein the distal end includes an apparatus having a first, retracted position and a second, expanded position, wherein the apparatus comprises a plurality of tips, and the apparatus further includes a cylinder having a distal end and a proximal end, and the cylinder is movable between a retracted position and an extended position, wherein when the cylinder is in its extended position it contacts the tips and moves them apart and into the second, expanded position of the apparatus; and
(b) a housing at the proximal end of the stem, the housing defining an inner cavity and comprising an external surface and a control on the external surface that is connected to the cylinder, wherein the stem has a lumen configured to permit fluid to flow therethrough and into the inner cavity, and the control is movable between a first position and a second position, wherein the cylinder is in its retracted position and the apparatus is in its first, retracted position when the control is in its first position, and the cylinder is in its extended position and the apparatus is in its second, expanded position when the control is in its second position, and the proximal end of the cylinder is inside of the inner cavity of the housing when the control is in its second position and the cylinder is in its extended position.

US Pat. No. 11,065,092

PROTECTIVE DEVICE FOR THE HEAD AND EARS OF AN ANIMAL


1. A protective device for an animal head including animal ears, a lower jaw, and a neck, the device having a front edge, a rear edge, a longitudinal central axis between the front edge and rear edge, and a width transverse to the central axis, the device comprising:a rear portion comprising a right neck strap and a left neck strap each having an inner end at said central axis and an outer end, and each of the neck straps extending out transversely from the central axis, so that a right strap axis extending from said central axis to the outer end of the right neck strap and a left strap axis extending from said central axis to the outer end of the left neck strap are each perpendicular to the central axis, and the right and left neck strap are fastenable in a neck loop for encircling the animal neck behind the animal ears; and
a front portion having right and left wings each having an inner end at said central axis and a wing outer end, and each of the right and left wings extending out transversely from the central axis, so that a right wing axis extending from said central axis to the wing outer end of the right wing and a left wing axis extending from said central axis to the wing outer end of the left wing are each perpendicular to the central axis, and the right and left wings being fastenable to form a head loop for encircling the animal head over the animal ears and under the lower jaw of the animal; wherein the head loop is longitudinally distanced forward from the neck loop except at a junction that connects a rear edge of the front portion to a front edge of the rear portion;
wherein, in use on an animal head, the protective device is oriented so that the central axis is in an upward position and extends longitudinally along a top region of the animal head, the right neck strap and left neck strap extend down from the central axis and are fastened under the animal neck, and the right wing and the left wing extend down from the central axis and down over the animal ears and are fastened under the lower jaw of the animal.

US Pat. No. 11,065,091

POWERED ORAL CARE IMPLEMENT

Colgate-Palmolive Company...


1. A powered oral care implement comprising:a housing including a cavity;
one or more electrically conducting elements disposed in the cavity;
a power source electrically connected to each of the one or more electrically conducting elements, wherein applying a current to individual of the one or more electrically conducting elements generates a field at the individual of the electrically conducting elements;
a cleaning element disposed on the housing to at least partially cover the cavity; and
a dentifrice slurry in the cavity, wherein the dentifrice slurry comprises one or more precursors converted by the electrically conducting elements to active species, and wherein the active species include at least one of a whitening agent, an enamel modifier, or an anti-bacterial.

US Pat. No. 11,065,090

DENTAL IMPLANT WITH CODED UPPER SURFACE

Biom et 3I, LLC, Palm Be...


1. A dental implant for insertion into bone within a patient's mouth, comprising:a body having a bone-engaging exterior surface, an anti-rotational feature for non-rotationally mating with a healing abutment during a gingival-healing period, and an upper region, the upper region including an upper surface for engaging the healing abutment; and
a scannable code on the upper surface for providing information of at least two features of the dental implant, the scannable code including:
a circumferentially extending marker having a first length and having a radius of curvature that is centered around a central axis of the dental implant, wherein the radius of curvature provides a position of the central axis, and wherein the first length extends less than 360 degrees around the circumference of the dental implant and corresponds to a first size dimension of the dental implant, wherein the scannable code is scanned in response to the healing abutment being removed from the dental implant.

US Pat. No. 11,065,089

AESTHETIC ORTHODONTIC LIGATURE

3M INNOVATIVE PROPERTIES ...


1. An orthodontic ligature for ligating an archwire to an orthodontic bracket, the ligature comprising:an elongated rib having a first longitudinal axis, the rib comprising a stem portion including a certain cross-sectional geometry and a coupling portion extending from the stem portion to a distal end, wherein the coupling portion includes a tip region with a pair of opposing elongated channels disposed on either side of a central rail; and
a latching head extending from the stem portion and defining a passage, the passage including one or more deflectable structures projecting into the passage and a second longitudinal axis that is perpendicular to the first longitudinal axis, each deflectable structure of the one or more deflectable structures received in one of the channels as the distal end is drawn through the passage,
wherein the coupling portion includes a plurality of spaced apart engagement features having a modified cross-sectional geometry relative to the stem portion, the plurality of spaced apart engagement features adapted to matingly engage with the deflectable structures in the passage to inhibit removal from the passage in certain directions when the coupling portion is received in the passage,
wherein the plurality of engagement features each include a first and a second flat locking surface facing in a direction towards the latching head and a first and a second tapered wall surface having an at least partially frustoconical configuration, wherein the first and second tapered wall surfaces are directly opposed on either side of the central rail.

US Pat. No. 11,065,088

SELF-LIGATING ORTHODONTIC BRACKET

Ormco Corporation, Orang...


1. A self-ligating orthodontic bracket for coupling an archwire with a tooth, comprising:a bracket body that is configured to be mounted to the tooth and that includes an archwire slot having a pair of opposed slot surfaces projecting from a base surface, a support surface intersecting with one of the pair of opposed slot surfaces, and a retaining groove between the support surface and the base surface and opening in a labial direction to the support surface when the bracket body is mounted to a labial surface of the tooth, wherein the retaining groove includes a closed end, one of the opposed slot surfaces defines a slot surface plane, and the retaining groove is positioned on a first side of the slot surface plane; and
a ligating slide that includes a projecting portion and is movable along the support surface from an opened position to a closed position, wherein the projecting portion projects lingually from a lingual surface of the ligating slide and is received in the retaining groove and during movement of the ligating slide, the projecting portion moves within the retaining groove on the first side of the slot surface plane during the entire travel of the ligating slide between the opened and closed positions.

US Pat. No. 11,065,087

ORTHODONTIC BRACKET APPARATUS AND METHOD FOR TREATING A MALOCCLUSION

Premier Orthodontic Desig...


1. An orthodontic bracket apparatus for treating a dental malocclusion, comprising: a bracket base which is configured for releasable attachment to an anterior facing surface of a tooth; at least one bracket body cooperates with the bracket base without removal of the bracket base from the anterior facing surface of the tooth and defines a three-sided arch wire slot in an anterior surface portion having two spaced-apart, parallel side walls, a slot opening, and a base wall opposite the slot opening; a bracket body insert releasably carried within the arch wire slot of the at least one bracket body adjacent the base wall, and wherein the bracket body insert has an elongated main body and an engaging portion that extends outwardly from the elongated main body so as to frictionally communicate with the bracket base to positionally secure the at least one bracket body in one of a plurality of predetermined angular orientations relative to the bracket base, and further having an anterior facing surface that forms a posterior portion of the arch wire slot; anda retention pin,
wherein the at least one bracket body defines a medial passageway communicating from the base wall to an opposing posterior surface of the at least one bracket body, wherein a transversely extending through-hole is defined in the at least one bracket body, is located spacedly adjacent to the opposing posterior surface and is perpendicular to the arch wire slot, and wherein the transversely extending through-hole intersects the medial passageway and is further configured to releasably carry the retention pin therein,
wherein the elongated main body has a first end, a second end, a top, a bottom, and a posterior facing surface, and an engagement member is-configured to be axially received within the medial passageway,
wherein the engagement member extends generally perpendicularly from the posterior facing surface medially between the first end and the second end, and wherein the engagement member further has a distal end which is spaced apart from the elongated main body and further defines an elongated hole communicating between the top and the bottom and between the distal end and the elongated main body,
wherein when the engagement member is received within the medial passageway, the elongated hole is aligned with the transversely extending through-hole, and the engagement member further defines friction ridges thereon which frictionally communicate with peripheral surfaces of the medial passageway so as to substantially eliminate any relative movement between the engagement member and the at least one bracket body, and
wherein the elongated hole in cooperation with the retention pin extending therethrough allows limited axial movement of the bracket body insert relative to the at least one bracket body so as to allow the at least one bracket body to be rotatably moved relative to the bracket base to any one of the predetermined angular orientations when the bracket body insert is moved axially relative to the at least one bracket body.

US Pat. No. 11,065,085

TOOTH-POSITIONING APPLIANCE, SYSTEMS AND METHODS OF PRODUCING AND USING THE SAME

Archform Inc., Sunnyvale...


1. An orthodontic appliance for adjusting the position of teeth of a patient, comprising:a tooth-clasping arrangement shaped to secure the orthodontic appliance to at least one tooth; and
a flexible arrangement connected to the tooth-clasping arrangement, wherein the flexible arrangement is formed integrally with the tooth-clasping arrangement from a shell of the orthodontic appliance and a topography of the flexible arrangement is different than a topography of the tooth-clasping arrangement and the flexible arrangement is more flexible than the tooth-clasping arrangement, the topography of the flexible arrangement including topographic features that are arranged in a repeating pattern,
wherein the topographic features include a central structure having three or more legs that extend out radially from a central point and connect to another topographic feature via a connecting structure, the connecting structure including a curved line that joins a leg from a first topographic feature with a leg from a second topographic feature.

US Pat. No. 11,065,084

METHOD AND SYSTEM FOR PREDICTING SHAPE OF HUMAN BODY AFTER TREATMENT

OSAKA UNIVERSITY, Suita ...


3. A method for predicting a facial shape after an orthodontic treatment comprising:a step of extracting multi-dimensional pre-orthodontic feature vectors Fpre(i) which have, as elements, a plurality of feature variables that are selected in advance for a human facial shape based on pre-orthodontic three-dimensional face data of a plurality of patients who have received an orthodontic treatment;
a step of classifying case data of the plurality of patients into a plurality of classes by carrying out clustering processing of a group of pre-orthodontic feature vectors Fpre(i) of the plurality of patients, and cluster centers Gpre(I) of each case class;
a step of extracting a multi-dimensional subject patient feature vector Fnew having the feature variables as elements based on three-dimensional face data of a new patient contemplating an orthodontic treatment (patient as an evaluation subject);
a step of selecting, from a plurality of the cluster centers Gpre(I) after the clustering, a similar case class having a cluster center that has the shortest distance from the subject patient feature vector Fnew;
a step of calculating pre-orthodontic facial shape models Hpre (i=i1, i2, . . . , ik) as facial shape models of the selected similar case class in which the arrangements of feature points obtained from pre-orthodontic three-dimensional face data of each selected case patient belonging to the selected similar case class are normalized;
a step of calculating post-orthodontic facial shape models Hpost (i=i1, i2, . . . , ik) of the selected similar case class in which the arrangements of feature points obtained from post-orthodontic three-dimensional face data of each case patient belonging to the selected similar case class are normalized;
a step of calculating a vector average AVEpre of pre-orthodontic facial shape models Hpre (i=i1, i2, . . . , ik) of each case patient belonging to the selected similar case class;
a step of calculating a vector average AVEpost of post-orthodontic facial shape models Hpost (i=i1, i2, . . . , ik) of each case patient belonging to the selected similar case class;
a step of calculating a facial shape vector average difference AVEpost-AVEpre that is obtained by subtracting the vector average AVEpre of pre-orthodontic facial shape models from the vector average AVEpost of post-orthodontic facial shape models;
a step of calculating a subject patient facial shape model Hnew as a facial shape model of the new patient in which the arrangement of feature points obtained from the three-dimensional face data of the new patient is normalized;
a step of calculating a three-dimensional predicted facial shape model Hprd as predicted after an orthodontic treatment of the new patient by modifying the facial shape model Hnew of the new patient with the facial shape vector average difference AVEpost?AVEpre of each case patient belonging to the selected similar case class; and
determining a treatment plan for the new patient based on the calculated three-dimensional predicted facial shape model Hprd; and
displaying a three-dimensional lateral view of the new patient based on the calculated three-dimensional predicted facial shape model Hprd.

US Pat. No. 11,065,083

BONE FOUNDATION GUIDE SYSTEM AND METHOD

NATIONAL DENTEX, LLC, Pa...


1. A kit, comprising:(a) a bone foundation guide having a first side and a second side, the first side of the bone foundation guide being configured to engage at least a portion of a bone segment of an alveolar ridge of a patient;
(b) a dental implant surgical guide, the dental implant surgical guide having a body with one or more apertures to locate one or more implants in the alveolar ridge of the patient; and
(c) a gasket, the gasket having a thickness corresponding to a depth of tissue removed from the bone of the alveolar ridge of the patient;
wherein the second side of the bone foundation guide is configured to support the dental implant surgical guide or the gasket while the first side of the bone foundation guide engages the alveolar ridge of the patient;
the gasket including one or more protrusions, the bone foundation guide defining one or more receptacles configured to receive the one or more protrusions of the gasket to thereby secure the gasket to the bone foundation guide.

US Pat. No. 11,065,082

TREATMENT METHOD FOR A SERVICE WATER SUPPLY UNIT


1. A method, for treating a service water supply unit of a dental treatment unit, the service water supply unit comprising a pressurized water vessel, the method comprising the following steps, in order:(VS1) cleaning the service water supply unit, including cleaning the pressurized water vessel, using a cleaning agent,
(VS3) disinfecting the service water supply unit, including disinfecting the pressurized water vessel, using a disinfecting agent,

wherein the disinfection of the pressurized water vessel proceeds by means of immersion disinfection and comprises the following steps:placing the pressurized water vessel into a disinfection tank filled with the disinfecting agent such that the pressurized water vessel is completely covered by the disinfecting agent and an interior volume of the pressurized water vessel remains free of air bubbles,
allowing the disinfecting agent to act for a contact time, and
removing the pressurized water vessel from the disinfection tank.

US Pat. No. 11,065,081

STERILIZABLE WIRELESSLY DETECTABLE OBJECTS FOR USE IN MEDICAL PROCEDURES AND METHODS OF MAKING SAME

COVIDIEN LP, Mansfield, ...


1. A wirelessly detectable object for use in a medical procedure, comprising:a medical procedure object; and
an attachment structure detachably coupled to the medical procedure object, the attachment structure including:a pouch;
a first transponder; and
a second transponder,

wherein the first transponder is freely movable within in the pouch and the second transponder is fixedly secured in the pouch, and
wherein one of the first or second transponders includes a directional antenna disposed within the pouch.

US Pat. No. 11,065,080

METHOD AND APPARATUS TO ACCOUNT FOR TRANSPONDER TAGGED OBJECTS USED DURING CLINICAL PROCEDURES, EMPLOYING A TROCAR

Covidien LP, Mansfield, ...


1. An apparatus for use in clinical environments, the apparatus comprising:a trocar, the trocar having a cannula with a proximal end and a distal end, the cannula delineates a lumen therethrough that extends from the proximal end to the distal end, with a proximal port at the proximal end which provides access to an interior of the lumen from an exterior of the cannula and with a distal port at the distal end which provides access to the interior of the lumen from the exterior of the cannula;
at least one trocar antenna, the at least one trocar antenna physically coupled to the trocar and positioned and oriented to provide wireless communications coverage of at least a portion of the interior of the lumen and any wireless communications transponders that pass through the lumen of the cannula; and
an interrogator communicatively coupled to the at least one trocar antenna and operable to cause the at least one trocar antenna to emit at least one of radio or microwave frequency energy interrogation signals and to detect response signals from any exposed wireless communications transponders that pass through the lumen of the cannula,wherein the at least one trocar antenna is communicatively detachably coupled to the interrogator via at least one electrical cable and a plug.


US Pat. No. 11,065,079

IMAGE-BASED SYSTEM FOR ESTIMATING SURGICAL CONTACT FORCE

THEATOR INC., Palo Alto,...


1. A non-transitory computer readable medium including instructions that, when executed by at least one processor, cause the at least one processor to execute operations enabling estimating contact force on an anatomical structure during a surgical procedure, the operations comprising:receiving, from at least one intracorporeal camera in an operating room, intracavitary image data of a surgical procedure;
analyzing the received intracavitary image data to determine an identity of an anatomical structure and to determine a condition of the anatomical structure as reflected in the intracavitary image data;
selecting a contact force threshold associated with the anatomical structure, the selected contact force threshold being based on the determined condition of the anatomical structure;
receiving an indication of actual contact force on the anatomical structure;
comparing the indication of actual contact force with the selected contact force threshold; and
outputting a notification based on a determination that the indication of actual contact force exceeds the selected contact force threshold.

US Pat. No. 11,065,078

SYSTEM AND METHOD FOR ENHANCED DATA ANALYSIS WITH SPECIALIZED VIDEO ENABLED SOFTWARE TOOLS FOR MEDICAL ENVIRONMENTS


1. A system for medical software tools, comprising:an image stream interface module configured to receive an image stream from a surgical camera, wherein said interface module includes internal system CPU, GPU and FPGA processors;
a user interface overlay module configured to provide a user interface overlay adapted for presentation over the image stream;
an optical sensor located corresponding with said surgical camera for registering changes in spectral characteristics reflected from a tissue surface under inspection;
a medical software tools module configured to provide a medical software tool through the user interface, the medical software tool being configured to perform an operation with respect to the image stream and provide an output adapted to be presented over the image stream;
a medical image processing system for processing patient medical data and corresponding said patient medical data with said momentary changes in spectral characteristics for generating optical signature data indicative of various patient conditions, wherein the medical software tool measures: a changes in color intensity and b rates at which said color intensities change in response to: heartbeat pushed blood, breathing pushed oxygen or light intensity or modulation from a light source;
image markers for delineating an area for inspection by a user and wherein said markers may define an area for a user to zoom in for a closer inspection of a portion of said patient tissue;
a checklist is both established by and utilized by said user for insuring that medical procedure steps are not missed.

US Pat. No. 11,065,077

MECHANICAL OPTICS FOR MIXED MODE SURGICAL LASER ILLUMINATION

Alcon Inc., Fribourg (CH...


1. A method for surgical illumination, the method comprising:projecting first light from a coherent light source into an optical fiber using a first condenser lens to direct the first light onto a mechanical optical element that redirects the first light to a focal spot at a fiber core of the optical fiber to generate second light, the second light used for illumination of a patient during a surgery;
causing the mechanical optical element to move the focal spot over the fiber core; and
transmitting the second light from the optical fiber to a second optical fiber that projects the second light onto the patient.

US Pat. No. 11,065,076

APPARATUS AND METHOD FOR APPLYING LIGHT IN OCULAR AND PERIOCULAR AREAS

LUMENIS LTD.


1. A method of treating meibomian gland dysfunction by an application of light energy, the method comprising:providing a handpiece having a light energy device at a distal end thereof;
providing a tip on the distal end of the light energy device, the tip having a shielding extension configured to be inserted behind an eyelid and comprised of a thermally insulative material;
inserting the shielding extension behind the eyelid;
contacting the anterior surface of the eyelid with the tip prior to applying light energy to the anterior surface of the eyelid;
applying light energy to the anterior surface of the eyelid;
wherein heat from the light energy device treats meibomian gland dysfunction.

US Pat. No. 11,065,075

SYSTEMS AND METHODS FOR A TISSUE EXPANDER

Reconstructive Technologi...


1. An extended tissue expander for filling with a filler material and implantation in the breast area of a patient, comprising:a breast tissue expander, comprising:a shell defining a closed interior volume configured to retain the filler material, wherein the shell comprises:an expandable anterior shell; and
a substantially nonexpandable posterior section, wherein the posterior section comprises an integrated portion of the shell; and

a port disposed through the shell and into the interior volume; and

an extension portion coupled to the breast tissue expander, wherein the extension portion:is integral to the posterior section of the shell, extending therefrom as a partially continuous annular rim, wherein the annular rim is absent from only approximately twenty percent to approximately forty percent of an inferior pole of the shell such that at least one of a medial and a lateral portion of the extension portion is present below a horizontal midline of the shell;
has a substantially uniform thickness;
is substantially nonexpandable to provide a backing to the shell such that the shell expands anteriorly away from the chest wall upon filling with filler material; and
is configured to be sutured.


US Pat. No. 11,065,074

EASY ACCESS BANDAGES

Genuine First Aid Interna...


1. A medical supply case comprising:a first hinged door disposed on a case body and provides access to a first compartment residing within the case body, the first hinged door including:a peg extend away from the first hinged door from a first end to a second end of the peg;
a securing member having a receipt configured to receive a portion of the second end of the peg, such that the peg and the securing member are coupled with one another at least a portion of the peg resides within the receipt and is at least partially secured within the receipt;
a first medical item secured between the securing member and the first hinged door, the first medical item including:a first end having an aperture configured to receive at east a portion of the peg, such that the first medical item is retained between the securing member and the first hinged door, thereby preventing the horizontal and lateral movements of the first medical item with respect to the first hinged door,
a second end of the first medical item being detachable from the first end when pulled away from the first end of the first medical item, such that the second end is dissociated from the first end: and


a second hinged door disposed on the case body and provides access to a second compartment residing within the case body.

US Pat. No. 11,065,073

DISPOSABLE MEDICAL DRAPE

Protection Products, Inc....


1. A drape for containment of medical waste fluids, comprising:a first drape for a medical patient table including:a central portion adapted to cover a horizontal portion of the medical patient table,
a first side portion extending laterally from the central portion and having at least a first fold portion,
a second side portion extending laterally from the central portion and having at least a first fold portion,
a first end cover extending beyond the central portion and forming an end barrier at a first end adapted to mate with the central portion along the horizontal portion, and the first side portion and second side portion along a lateral portion on each side respectively,
a second end cover extending beyond the central portion and forming an end barrier at the second end adapted to mate with the central portion along the horizontal portion, and the first side portion and second side portion along a lateral portion on each side respectively,
wherein said first drape is adapted to cover the medical patient table forming an impermeable barrier between a patient and the medical patient table, the first drape adapted to surround the horizontal portion of the medical patient table and extending beyond the sides and ends of the medical patient table toward a floor surface,
at least one attachment point on said first side portion, and
at least one attachment point on said second side portion, said attachment points on the first side portion and on the second side portion are separated from the horizontal central portion by a length of the first side portion and of the second side portion,
wherein said first fold portions are configured to double over said first side portion and said second side portion respectively, along a fold to form a trough at a bottom edge of said first side portion and of said second side portion, wherein said trough is adapted to collect medical fluids along the trough, and

at least one drape cover extension including a flap for covering a space between the first drape and the drape cover extension, the flap extending between the first drape and an end of a drape cover extension body,
wherein the drape cover extension is configured to extend substantially perpendicularly away from the first drape central portion to extend the drape coverage continuously beyond the medical patient table and extending to an extension piece mating with the medical patient table.

US Pat. No. 11,065,072

ROBOTIC SURGICAL SYSTEMS, INSTRUMENT DRIVE UNITS, AND DRIVE ASSEMBLIES

COVIDIEN LP, Mansfield, ...


1. A drive assembly of an instrument drive unit for use with a surgical instrument, the drive assembly comprising:a drive screw defining a longitudinal axis;
a drive unit engaged with a portion of the drive screw such that rotation of the drive screw about the longitudinal axis results in longitudinal movement of the drive unit relative to the drive screw;
a biasing element disposed in mechanical cooperation with the drive unit; and
a follower disposed in mechanical cooperation with the biasing element, the follower being longitudinally translatable relative to the drive screw;
wherein the biasing element is positioned between a portion of the drive unit and a portion of the follower.

US Pat. No. 11,065,071

MEDICAL MANIPULATOR SYSTEM AND OPERATING METHOD THEREOF

OLYMPUS CORPORATION, Tok...


1. A medical manipulator system comprising:a placement table on which a patient is placed;
at least one manipulator configured to support a treatment tool configured to treat the patient, the manipulator being configured to adjust a position and an orientation of the treatment tool;
a base portion configured to support the manipulator;
a sensor configured to detect objects which are present in a predetermined area including the manipulator and the placement table, the sensor being arranged at a bottom surface of the base portion separate from the at least one manipulator; and
a controller comprising at least one processor, wherein the at least one processor is configured to:calculate degrees of proximity between the objects detected by the sensor and the manipulator, and
generate, in case that the calculated degrees of proximity exceed a predetermined threshold, a control signal for preventing interference between the objects and the manipulator.


US Pat. No. 11,065,070

ROBOT SYSTEM AND METHOD OF OPERATING THE SAME

KAWASAKI JUKOGYO KABUSHIK...


1. A robot system comprising:a manipulator configured to receive a manipulating instruction from an operator;
a slave arm having a plurality of joints; and
a storage device storing a task program; and
a control device configured to control operation of the slave arm, wherein:when the slave arm is operating at a speed equal to or higher than a first predetermined threshold and when a correction instruction value to correct the operation of the slave arm is inputted from the manipulator during an automatic operation of the slave arm, the control device is configured to prevent the correction of the operation of the slave arm and continue the automatic operation of the slave arm,
when the slave arm is operating at a speed lower than the first predetermined threshold and when the correction instruction value to correct the operation of the slave arm is inputted from the manipulator during the automatic operation of the slave arm, the control device is configured to allow the correction of the operation of the slave arm, and
the control device is configured to add the correction instruction value to an operational instruction value, which is based on automatic operation information acquired from the task program, and perform the correction of the operation of the slave arm as a function of a sum of the correction instruction value and the operational instruction value.


US Pat. No. 11,065,069

ROBOTIC SPINE SURGERY SYSTEM AND METHODS

MAKO Surgical Corp., Ft....


1. A surgical robotic system comprising:a robotic manipulator;
a surgical tool configured to be coupled to said robotic manipulator to rotate about a rotational axis to place an implant in a spine of a patient;
a robotic controller coupled to said robotic manipulator to control movement of said surgical tool to place said rotational axis along a desired trajectory, maintain said rotational axis along said desired trajectory, and control installation of the implant in the spine of the patient so that the implant is placed at a desired location; and
a navigation system including a navigation controller configured to track a pose of said rotational axis relative to said desired trajectory,
wherein said robotic controller is configured to cause autonomous movement of said surgical tool to place the implant in the spine of the patient until the implant is within a predefined distance of said desired location, and thereafter, said robotic controller is configured to control manual manipulation of said surgical tool until the implant is placed at said desired location.

US Pat. No. 11,065,068

SYSTEMS, APPARATUS AND METHODS FOR CONTINUOUSLY TRACKING MEDICAL ITEMS THROUGHOUT A PROCEDURE

Medline Industries, Inc.,...


1. An apparatus for tracking medical instruments throughout a procedure comprising:a mobile cart movable about a room or from room to room and having a support extending therefrom;
a single camera for tracking movement and detecting position of a plurality of medical instruments during a medical procedure as at least one of the plurality of medical instruments is moved between multiple zones at least including a prep zone and a procedure zone, the single camera being mounted to the support extending from the mobile cart;
a controller connected to and collecting images from the camera;
a display in electrical communication with the controller and/or the camera for displaying medical instrument data pertaining to the movement and/or position of the plurality of medical instruments; and
wherein the plurality of medical instruments each have an instrument marker and the controller is capable of tracking movement and detecting position of the plurality of medical instruments from their respective instrument markers, the instrument marker is a two-dimensional (2D) barcode or a three-dimensional (3D) barcode machine readable by the controller via the camera from first and second angles without the need to move the camera and with the first and second angles being greater than thirty degrees (30°) apart.

US Pat. No. 11,065,067

SYSTEM AND METHOD FOR PREPARING BONE

MAKO Surgical Corp., Ft....


9. A method for repairing a bone fracture, comprising:using a computer to create a surgical plan, wherein creating the surgical plan comprises:determining a desired relationship between at least a first bone piece and a second bone piece that are separated by the bone fracture; and
planning preparation of the first bone piece to include a prepared anatomical structure configured to directly mate with the second bone piece to align the first bone piece with the second bone piece such that when aligned, the first bone piece and the second bone piece will achieve the desired relationship; and

preparing the first bone piece to include the prepared anatomical structure according to the surgical plan.

US Pat. No. 11,065,066

METHOD FOR ENABLING MEDICAL NAVIGATION WITH MINIMISED INVASIVENESS


1. A method, executed by a computer, for tracking a bone, comprising the steps of:a) receiving bone registration data that represent locations of points on the surface of the bone;
b) calculating, from the bone registration data, a current relative position between the bone and a medical instrument that bears a marker device;
c) determining an offset between the current relative position and a desired relative position;
d) outputting indication information that is based on the offset;
e) receiving bone reregistration data that represent locations of points on the surface of the bone, wherein the bone reregistration data is a reduced set of data as compared to the bone registration data;
f) augmenting the bone reregistration data based on the bone registration data;
g) calculating positional relationship data from the bone reregistration data; and
h) tracking the bone by tracking the marker device and using the positional relationship data.

US Pat. No. 11,065,065

SPINAL IMPLANT SYSTEM AND METHODS OF USE

Warsaw Orthopedic, Inc., ...


1. A method for treating a spine, the method comprising the steps of:imaging a patient anatomy including a vertebra;
selecting an implant strategy according to the imaging for a screw shaft;
generating fluoroscopic images of at least a portion of a robot;
registering the imaging of the patient anatomy with the fluoroscopic images;
engaging the screw shaft with the vertebra via the surgical driver according to the implant strategy;
acquiring a first set of data points representative of a three dimensional position of the screw shaft relative to the vertebra;
transmitting the first set of data points to a computer database;
manipulating the patient anatomy;
acquiring a second set of data points representative of a three dimensional position of the screw shaft relative to the vertebra subsequent to manipulating the patient anatomy;
transmitting the second set of data points to the computer database;
retrieving the second set of data points from the computer database;
aligning an implant receiver with the screw shaft according to the second set of data points; and
engaging the implant receiver with the screw shaft to comprise a bone screw.

US Pat. No. 11,065,064

CALIBRATION OF A RIGID ENT TOOL

Biosense Webster (Israel)...


1. An apparatus, comprising:a magnetic field generator;
a first magnetic field sensor configured for attachment to a proximal end of a rigid surgical tool configured to be inserted into a living body, wherein the rigid surgical tool comprises a handle and an insertion tube, and wherein the first magnetic field sensor is configured to be coupled to the handle and the insertion tube and to be disposed coaxially with and between both the handle and the insertion tube when attached to the proximal end of the rigid surgical tool;
a calibration device, including a second magnetic field sensor and a proximity sensor, wherein the first and the second field sensors generate respective location signals responsive to a magnetic field emanating from the magnetic field generator and traversing the sensors, and wherein the proximity sensor generates a proximity signal indicating a contact with the calibration device; and
a control unit, which receives the signals from all the sensors, extracts respective location and orientation coordinates of the magnetic field sensors based on the signals, computes a conversion relation between the coordinates of the first magnetic field sensor and a distal end of the tool that is brought into contact with the calibration device, and subsequently applies the conversion relation, together with the coordinates of the first magnetic field sensor, in providing a visual indication of a location of the distal end of the tool inside the body.

US Pat. No. 11,065,063

UTILIZATION OF LASER INTERSTITIAL THERMOTHERAPY GUIDED WITH REAL TIME THERMAL MRI

Board of Regents, The Uni...


1. A method for applying thermal energy to a target tissue in a region of interest, the method comprising:coupling a plurality of fiducial markers to tissue proximal to the region of interest;
obtaining a magnetic resonance image (MRI) of the region of interest;
registering the plurality of fiducial markers with a stereotactic image guidance system;
verifying surface accuracy of the stereotactic image guidance system;
inserting an MRI-compatible instrument into the region of interest;
verifying sub-surface accuracy of the stereotactic image guidance system;
inserting a laser fiber into the target tissue in the region of interest;
applying thermal energy to the target tissue; and

monitoring temperature in the target tissue and the region of interest, wherein the MRI-compatible instrument is a needle comprising a removable trocar and wherein the method further comprises:removing the removable trocar from the needle and inserting a wire through the needle; and
inserting a cannula over the wire, wherein inserting a laser fiber into the target tissue in the region of interest comprises inserting the laser fiber through the cannula.

US Pat. No. 11,065,062

SYSTEMS AND METHODS OF TRACKING AND ANALYZING USE OF MEDICAL INSTRUMENTS

COVIDIEN LP, Mansfield, ...


1. A method for a medical procedure, comprising:obtaining a plurality of data sets from a respective plurality of sensors disposed in a medical instrument, the plurality of sensors comprising at least one first sensor configured to measure acceleration, at least one second sensor configured to measure rotation, and at least one third sensor configured to measure direction of movement;
determining, based on a decrease in measured acceleration from above a first threshold to below a second threshold, a time at which the medical instrument transitions from being positioned outside a patient's body to being positioned within the patient's body cavity via the medical device entering the patient's body cavity through an access point;
displaying a representation of the access point through which the medical instrument enters the patient's body cavity;
correlating each of the obtained plurality of data sets from the respective plurality of sensors with a time when the plurality of data sets was obtained;
determining, for each of the obtained plurality of data sets, a maximum acceleration of the medical instrument;
comparing the determined maximum acceleration from each of the obtained plurality of data sets;
identifying which of the plurality of obtained data sets indicates a greatest maximum acceleration;
storing the correlated plurality of data sets and the correlated times;
accessing the stored correlated plurality of data sets and the stored correlated times after a medical procedure has been completed; and
displaying and animating movement of a representation of the medical instrument based on the accessed correlated plurality of data sets and time the accessed correlated times, wherein the representation of the medical instrument is superimposed over a three dimensional (3D) representation of the patient's body cavity and animating movement of the superimposed representation of the medical instrument is in real time.

US Pat. No. 11,065,061

SYSTEMS AND METHODS FOR PERFORMING IMAGE GUIDED PROCEDURES WITHIN THE EAR, NOSE, THROAT AND PARANASAL SINUSES

Acclarent, Inc., Irvine,...


1. A method for image guided performance of a treatment procedure to treat an ear, nose, throat or paranasal sinus in a patient, the method comprising:(a) using a monitor of an image guidance system to view an image of the patient's head;
(b) calibrating the position of the patient's head using a plurality of fiducial markers;
(c) using the monitor of the image guidance system to view the positions of the fiducial markers relative to the image of the patient's head;
(d) coupling a first working device to a computer of the image guidance system, wherein the first working device comprises a sensor at a distal end portion of the first working device, wherein the first working device communicates at least one calibration detail to the computer upon being coupled thereto;
(e) operating a transmitter assembly positioned outside of the patient's head to emit an electromagnetic field;
(f) inserting the first working device into the patient's head through the patient's nostril so that the sensor is within the patient's head;
(g) determining a position of the sensor within the patient's head based upon an interaction of the sensor with the electromagnetic field and the at least one calibration detail and viewing a portion of the first working device on the monitor relative to the image of the patient's head based on the position of the sensor; and
(h) using at least the first working device to treat the ear, nose, throat, or paranasal sinus of the patient while viewing the monitor,
wherein using at least the first working device to treat the ear, nose, throat, or paranasal sinus of the patient comprises dilating an anatomical passageway within the ear, nose, or throat of the patient.

US Pat. No. 11,065,060

IDENTIFY ABLATION PATTERN FOR USE IN AN ABLATION

Vektor Medical, Inc., Ca...


1. A method performed by one or more computing systems for identifying a potential ablation pattern for a patient heart of a patient, the method comprising:accessing a patient cardiogram of the patient;
identifying non-ablation pattern information of a non-ablation pattern simulation of a heart, the non-ablation pattern simulation not based on an ablation pattern, the non-ablation pattern information being identified based on similarity of a simulated cardiogram generated based on the non-ablation pattern simulation to a patient cardiogram of the patient;
identifying an ablation pattern based on similarity of non-ablation pattern information to ablation pattern information associated with an ablation pattern simulation, the ablation pattern simulation based on the identified ablation pattern; and
outputting an indication of the identified ablation pattern as the potential ablation pattern for the heart of the patient.

US Pat. No. 11,065,059

SYSTEMS AND METHODS OF CONTINUOUS REGISTRATION FOR IMAGE-GUIDED SURGERY

INTUITIVE SURGICAL OPERAT...


1. A method of registering a model of one or more anatomic passageways of a patient to a patient space, the method comprising:accessing a set of model points of the model of one or more anatomic passageways of the patient, the model points being associated with a model space;
collecting a first set of measured points along a length of a catheter inserted into the one or more anatomic passageways of the patient, the measured points determined by a shape of the catheter in the patient space;
assigning points of the first set of measured points to a plurality of first subsets of measured points;
registering the first subsets of measured points with the set of model points to produce a first plurality of registration candidates;
comparing the registration candidates to identify an optimal subset associated with an optimal registration of the first plurality of registration candidates;
displaying a visual representation of the optimal registration in a user interface provided by a display, the optimal registration translating the set of model points and at least one subset of the first set of measured points into a common space;
collecting additional measured points along the length of the catheter;
assigning the additional measured points to the plurality of first subsets of measured points to generate a plurality of second subsets of measured points;
registering the second subsets of measured points with the model points to produce a second plurality of registration candidates; and
comparing each of the second registration candidates to identify an optimal second subset associated with a second optimal registration from the second plurality of registration candidates.

US Pat. No. 11,065,058

USING A PREDETERMINED ABLATION-CURRENT PROFILE

Biosense Webster (Israel)...


1. A system, comprising:a computer memory; and
a processor, configured to:while simulating an application of an electric current to simulated tissue, control an amplitude of the electric current such that a maximum subsurface temperature of the simulated tissue increases toward a predefined threshold without exceeding the predefined threshold, wherein the processor is configured to, by controlling the amplitude, cause the amplitude to initially monotonically increase to a maximum value,
derive a function of time from values of the amplitude over the simulated application, wherein the processor is configured to derive the function of time by fitting a predefined function template to the values of the amplitude over the simulated application, and
store the function of time in the computer memory for subsequent use in an ablation procedure.


US Pat. No. 11,065,057

DEVICES, SYSTEMS, AND METHODS FOR REDUCING AND FIXING FRACTURED BONES

Bullseye Hip Replacement,...


1. A device for reducing a fractured bone, the device comprising:an implant comprising an outer perimeter having a first portion and a plurality of apertures through the implant shaped to receive fasteners for fixing the implant to the bone;
a body, separate from the implant, having a bone facing surface shaped to match a shape of a surface of a reduced fractured bone at a location proximate an installation position of the implant; and
an implant alignment member extending from the body and having a surface shaped to receive the implant in a predetermined orientation and comprising an outer perimeter having a concavity formed therein, the outer perimeter being shaped to match and receive therein a first portion of the outer perimeter of the implant.

US Pat. No. 11,065,056

SYSTEM AND METHOD OF GENERATING A MODEL AND SIMULATING AN EFFECT ON A SURGICAL REPAIR SITE

SOFRADIM PRODUCTION, Tre...


1. A method of generating a computer-based observable model of an implantable repair mesh secured to a tissue of a patient, comprising:processing data corresponding to a patient using a computing device including a processor and a memory storing a software application executable by the processor;
indicating an implantable repair mesh and a fixation for securing the implantable repair mesh to the tissue of the patient;
indicating a distribution of the fixation about the implantable repair mesh;
generating a computer-based interactive observable model of the implantable repair mesh secured to the tissue of the patient based on the indicated implantable repair mesh, the indicated fixation, and the indicated distribution of the fixation; and
displaying, on a display operably associated with the computing device, the computer-based interactive observable model depicting the indicated distribution of the fixation about the implantable repair mesh.

US Pat. No. 11,065,055

DEVICES AND METHODS FOR CREATING CONTINUOUS LESIONS

MicroCube, LLC, Fremont,...


1. A method of treating tissue at an anatomical site, the method comprising:positioning a treatment system adjacent to the anatomical site, where the treatment system includes a closed loop assembly comprising a first elongate arm, a second elongate arm, and an ablation device that advanceable through the first elongate arm and coupled to a distal portion of the second elongate arm by a flexible member;
stabilizing the closed loop assembly within the anatomical site by manipulating either the first elongate arm or the second elongate arm to force the closed loop assembly against tissue;
advancing the ablation device through the first elongate arm and positioning the ablation device using the flexible member such that after being stabilized the closed loop assembly stabilizes the ablation device;
treating the tissue with the ablation device at a first region; and
placing at least one electrode against the tissue to transmit and receive electrophysiological signals from the tissue where the at least one electrode is located on the flexible member.

US Pat. No. 11,065,054

SURGICAL RESECTION APPARATUS

CREO MEDICAL LIMITED, Ch...


1. A surgical cutting apparatus having:a microwave radiation source arranged to generate a microwave radiation signal;
a surgical instrument for cutting biological tissue, the surgical instrument comprising an antenna connected to the microwave radiation source and arranged to emit a substantially uniform microwave radiation field;
a reflected radiation detector connected between the microwave radiation source and the antenna to detect signals reflected back from the antenna;
a reflected power monitor arranged to detect a signature event in the reflected signals detected by the reflected radiation detector during a cutting process, wherein the signature event is a detectable behaviour in the reflected signals and is at least one of the following:
a certain rate of change of reflected power for a certain time slot;
a certain rate of change of reflected power for a certain duration;
a constant level of reflected power for a certain time slot;
a constant level of reflected power for a certain duration;
a constant voltage for a certain duration; or
a voltage spike in the reflected signal;
a power level adjuster connected between the microwave radiation source and antenna and arranged to automatically adjust a power level of the microwave radiation signal received by the antenna if the reflected power monitor detects the signature event; and
wherein the power level adjustor is arranged to:
reduce the power level from a first value to a second non-zero value when the signature event is detected; and
automatically ramp the power level back up from the second non-zero value to the first value in a predetermined recovery time period after reducing the power level.

US Pat. No. 11,065,053

ABLATION CABLE ASSEMBLIES AND A METHOD OF MANUFACTURING THE SAME

COVIDIEN LP, Mansfield, ...


1. An ablation cable assembly comprising:a rigid portion disposed at a proximal end portion of the ablation cable assembly and configured to couple to a source of electrosurgical energy and prevent fluid ingress;
a flexible central portion extending distally from the rigid portion, the central portion including:an inner conductor;
a dielectric disposed about the inner conductor; and
a conductive braid disposed about the dielectric and forming an outer-most layer of the central portion, the conductive braid having a proximal portion disposed at the proximal end portion of the ablation cable assembly and directly coupled to a distal portion of the rigid portion, wherein adjacent to a distal end of the rigid portion, the proximal portion of the conductive braid transitions from having a first diameter surrounded by the rigid portion to having a second diameter greater than the first diameter and extending distally from the distal end of the rigid portion; and

a radiating portion extending distally from the central portion and configured to deliver electrosurgical energy to tissue.

US Pat. No. 11,065,052

CATHETER ELECTRODE ASSEMBLIES AND METHODS OF CONSTRUCTION THEREFOR

St. Jude Medical, Atrial ...


1. An expandable catheter electrode assembly including an outer tubing defining a longitudinal axis, a plurality of structural support members, at least one of the plurality of structural support members comprising:a flexible circuit including a plurality of electrical traces and a substrate; and
an electrode electrically coupled with at least one of the plurality of electrical traces; and

a nonconductive liner disposed within at least a portion of the electrode.

US Pat. No. 11,065,051

SPECIMEN RETRIEVAL DEVICE

COVIDIEN LP, Mansfield, ...


1. A specimen retrieval device, comprising:a port defining a longitudinal bore and a channel, the port possessing a proximal portion, a distal portion, and a cutting element fixedly attached to the distal portion; and
a specimen bag defining a reservoir and having a first opening at a proximal portion of the specimen bag and a second opening spaced from the first opening, the first and second openings communicating with the reservoir, the first opening affixed to and in fluid communication with the distal portion of the port, and the second opening defined by a mouth of the specimen bag.

US Pat. No. 11,065,050

METHODS, SYSTEMS, AND DEVICES RELATING TO SURGICAL END EFFECTORS

Board of Regents of the U...


1. An in-vivo vessel sealing end effector, the end effector comprising:(a) an in vivo end effector body coupleable to an arm of an in vivo robotic device, wherein the arm and the end effector body are configured to be positioned entirely within a cavity of a patient, the end effector body comprising:(i) a cautery component shaft disposed within the body; and
(ii) a first collar disposed around and operably coupled to the cautery component shaft; and

(b) a bipolar vessel cautery component operably coupled to the end effector body, the cautery component comprising:(i) a stationary jaw coupled to a distal end of the cautery component shaft;
(ii) a mobile jaw pivotally coupled to the distal end of the cautery component shaft; and
(iii) a cutting component moveably coupled to the cautery component shaft.


US Pat. No. 11,065,049

ELECTROSURGICAL DEVICE WITH ASYMMETRIC SEAL COMPRESSION

Gyrus Acmi, Inc., Westbo...


1. An end effector assembly of a forceps comprising:a first jaw member with a first sealing surface and a second sealing surface;
a second jaw member with a first sealing surface and a second sealing surface, the first jaw member and the second jaw member being movable relative to each other between an open position and a closed position, the first jaw member and the second jaw member including a blade slot defined therein and extending substantially along the first jaw member and the second jaw member, the first sealing surfaces being positioned on an opposite side of the blade slot than the second sealing surfaces; and
a cutting blade that reciprocates in the blade slot,
wherein when the first jaw member and the second jaw member are in closed position, the first sealing surface of the first jaw member and the first sealing surface of the second jaw member are separated by a first constant, uniform gap extending continuously from the blade slot to a first lateral side of the first and second jaw members and the second sealing surface of the first jaw member and the second sealing surface of the second jaw member are separated by a second constant, uniform gap extending continuously from the blade slot to a second lateral side of the first and second jaw members, the second constant, uniform gap being larger than the first constant, uniform gap.

US Pat. No. 11,065,048

FLEXIBLE CIRCUIT ARRANGEMENT FOR SURGICAL FASTENING INSTRUMENTS

Cilag GmbH International,...


1. A motor driven surgical system comprising:a handle assembly; and
an interchangeable surgical tool assembly, operatively coupled to the handle assembly, comprising:a nozzle assembly;
a proximal closure tube having a proximal end operatively coupled to a distal end of the nozzle assembly;
an articulation connector having a proximal end operatively coupled to a distal end of the proximal closure tube;
a surgical end effector comprising a first jaw and a second jaw and having a proximal end operatively coupled to a distal end of the articulation connector;
a flexible shaft circuit strip disposed within at least a portion of the proximal closure tube, at least a portion of the articulation connector, and at least a portion of the surgical end effector;
a knife member slideably disposed within the surgical end effector; and
a knife bar operatively connected to a proximal end of the knife member,
wherein the knife bar comprises a first laminated plate disposed on a first side of the flexible shaft circuit strip and a second laminated plate disposed on a second side of the flexible shaft circuit strip,
wherein the knife bar further comprising a first leaf spring disposed between the first side of the flexible shaft circuit strip and the first laminated plate, and a second leaf spring disposed between the second side of the flexible shaft circuit strip and the second laminated plate, and
wherein the knife bar is configured to reciprocate along a longitudinal axis of the proximal closure tube.


US Pat. No. 11,065,047

SYSTEMS, APPARATUSES, AND METHODS FOR PROTECTING ELECTRONIC COMPONENTS FROM HIGH POWER NOISE INDUCED BY HIGH VOLTAGE PULSES

Farapulse, Inc., Menlo P...


23. An apparatus, comprising:a set of electrodes disposable near cardiac tissue of a heart;
a signal generator coupled to the set of electrodes and configured to generate a pulse waveform;
a set of sensors disposable near patient anatomy;
at least one switch component coupled between an electronic device and the set of sensors, the at least one switch component configured to switch between a conducting state in which the electronic device is coupled to the set of sensors and a non-conducting state in which the electronic device is decoupled from the set of sensors, the at least one switch component including a pair of metal oxide semiconductor field effect transistors (MOSFETs), the pair of MOSFETs having a common source terminal and gate terminals coupled to one or more isolated gate drive circuits, the one or more isolated gate drive circuits configured to deliver a control signal to the gate terminals to switch the pair of MOSFETs between the conducting state and the non-conducting state; and
a processor coupled to the signal generator and the at least one switch component, the processor configured to:determine to deliver the pulse waveform to the set of electrodes during a set of cardiac cycles; and
for each cardiac cycle from the set of cardiac cycles:set the at least one switch component to the non-conducting state such that the electronic device is decoupled from the set of sensors; and
deliver, via the signal generator and after setting the at least one switch component to the non-conducting state, the pulse waveform to the set of electrodes such that the set of electrodes generates a pulsed electric field; and
set, after delivering the pulse waveform, the at least one switch component to the conducting state such that the electronic device is coupled to the set of sensors and can send signals to or receive signals from the set of sensors.



US Pat. No. 11,065,046

MODULATING NERVES WITHIN BONE

Relievant Medsystems, Inc...


1. A method of treating back pain of a subject, the method comprising:performing a spinal fusion procedure between two adjacent vertebral bodies; and
performing a nerve ablation procedure within at least one of the two adjacent vertebral bodies,
wherein the nerve ablation procedure comprises applying thermal energy to create a controlled heating zone sufficient to ablate a basivertebral nerve within the at least one of the two adjacent vertebral bodies,
wherein the controlled heating zone encompasses a terminus of the basivertebral nerve,
wherein the thermal energy is applied using at least one bipolar radiofrequency energy delivery device, and
wherein the spinal fusion procedure and the nerve ablation procedure are performed contemporaneously in a single treatment procedure.

US Pat. No. 11,065,045

DEVICES AND METHODS FOR TREATING BONE


1. A method of treating a fracture in a vertebral body, the method comprising:inserting a spinal system into the vertebral body in a collapsed state, the spinal system comprising:an upper plate, having a proximal end and a distal end;
a lower plate in opposition to the upper plate;
a posterior support leg engaged, at the proximal end, with the upper plate at a first corner and the lower plate at a second corner; and
an anterior support leg engaged, at the distal end, with the upper plate at a third corner and the lower plate at a fourth corner; and

expanding the spinal system to an expanded state, wherein the anterior support leg is configured to removably engage a plunger, wherein sliding movement of the plunger facilitates movement of the spinal system between the collapsed state and the expanded state,
wherein the first, second, third, and fourth corners have a reduced thickness and are flexible enough to allow the upper plate and the lower plate to move toward each other in the collapsed state and to move away from each other in the expanded state such that in the expanded state, the upper plate is generally perpendicular to at least one of the anterior and posterior support legs, and in the collapsed state, the upper plate is generally angled relative to at least one of the anterior and posterior support legs, and
wherein the spinal system is based towards the expanded state.

US Pat. No. 11,065,044

SURGICAL IMPLANT WITH POROUS REGION

ARTHREX, INC., Naples, F...


1. A suture anchor, comprising:a body that extends along a longitudinal axis between a drive head and a tip of the implant, said body including a cannulation disposed about said longitudinal axis and extending from said tip to said drive head, said body including an inner cylindrical wall that circumscribes said cannulation, said inner cylindrical wall being solid and non-porous;
a solid and non-porous thread that spirals around said body between said drive head and said tip, said solid thread and non-porous comprising a minor diameter (D1) and a major diameter (D2); and
a porous region circumferentially extending about said body between adjacent revolutions of said solid and non-porous thread, wherein the porous region extends from the minor diameter (D1) toward the cannulation;
wherein said porous region includes a plurality of interconnected pores.

US Pat. No. 11,065,043

ANTERIOR CERVICAL SPINE PLATE


1. A cervical plate comprising:a plate body formed to extend in a longitudinal direction thereof;
bone screws installed through the plate body;
two or more bone screw holes formed in the plate body to support head parts of the bone screws; and
a locking element configured to maintain the bone screws while being inserted into the bone screw holes, respectively,
wherein the locking element is rotatably mounted in the plate body, and
wherein, when a curvature of the plate body between the locking elements located at opposite ends in the longitudinal direction thereof is R3, and curvatures of the plate body from the locking elements located at opposite ends to the ends thereof are R4 and R5, respectively, the R4 and R5 are smaller than the R3.

US Pat. No. 11,065,042

BONE PLATE AND GUIDE BLOCK AND ATTACHMENT MECHANISM THEREOF

Flower Orthopedics Corpor...


1. A bone plate and complementary guide block system, comprising:a bone plate comprising a rigid plate body having a front and a rear, at least one post bore, and a plurality of bone plate bores therein, each bone plate bore having at least one angle of orientation; and
a guide block comprising a rigid guide block body having a front, a rear, a bottom surface, and a flat upper surface, an overhanging lip positioned at the rear of the guide block, the overhanging lip extending in an inferior direction from the upper surface, at least one post on the bottom surface, and a plurality of guide block bores therein, each guide block bore having at least one angle of orientation;
wherein the guide block is attachable to the bone plate such that the front of the guide block is positioned at the front of the bone plate, wherein the lip elevates the rear of the guide block from the bone plate to maintain the upper surface of the guide block and the bone plate in substantially parallel alignment, wherein the at least one post seats within the at least one post bore to releasably and toollessly attach the guide block to the bone plate, and wherein the plurality of guide block bores substantially align with the plurality of bone plate bores such that a fastener may pass through each of the plurality of guide block bores and each of the plurality of bone plate bores into bone.

US Pat. No. 11,065,041

DEVICE AND METHOD FOR BONE ADJUSTMENT WITH ANCHORING FUNCTION


1. A device for bone adjustment in a mammal, the device comprising:a bone adjusting housing, sized and adapted to be implanted entirely intramedullary in a femoral or tibial bone in said mammal said housing comprisingtwo or more anchoring devices adapted to be attached to the femoral or tibial bone in said mammal,
an adjustment device for exerting a force on said two or more anchoring devices, said adjustment device being adapted to postoperatively adjust at least one of a distance between or orientation of, at least two of said two or more anchoring devices,
an operation device comprising a motor, wherein said operation device is adapted to operate said adjustment device,
a gearbox connected to the motor, wherein an outgoing speed from the gear box is lower than a speed by the motor alone, accomplished by the gearbox, and wherein the outgoing speed of the gearbox is less than 10 turn per second during normal operation, and wherein said device for bone adjustments further comprises

a control device adapted to control the operation device, wherein the control device is programmed to control the device according to a pre-programmed time-schedule comprising a program of incremental changes.

US Pat. No. 11,065,040

SPINOUS PROCESS FIXATION SYSTEM AND METHODS THEREOF

Globus Medical, Inc., Au...


1. An implantable device, comprising:a barrel, the barrel having an upper portion and a lower portion;
an actuator assembly disposed in the barrel, the actuator assembly comprising a front ramped actuator in engagement with the barrel, a rear ramped actuator in engagement with the barrel, and a central screw that extends from the rear ramped actuator through the front ramped actuator;
a first plate, formed integrally with the barrel, comprising a first portion that extends from the upper portion, a second portion that extends form the lower portion, and a first spike assembly disposed in the first plate, the first spike assembly comprising one or more projections extending from a first side of the first plate; and
a second plate having multiple projections extending from a first side of the second plate, the second plate having a central bore adapted to adjustably receive the central screw for adjustment of a width between the first and second plates;
wherein the barrel is configured to transition from a collapsed form having a first height to an expanded form having a second height and wherein the second height is greater than the first height.

US Pat. No. 11,065,039

SPINAL IMPLANT AND METHODS OF USING THE SAME

Providence Medical Techno...


1. A spinal implant for implantation within a spinal facet joint, the implant comprising:a main body including:opposing top and bottom surfaces;
opposing front and rear surfaces;
opposing side surfaces; and
at least one lateral edge defined at an intersection between one of the opposing top and bottom surfaces and one of the opposing side surfaces;

at least one retaining feature positioned on at least one of the top and bottom surfaces of the main body, said retaining feature including a leading face, a trailing face, opposing lateral faces and a tip formed at an intersection between the faces; and
at least one securement feature associated with at least one surface of the main body to secure the implant within the spinal facet joint,
wherein:
each lateral face of the at least one retaining feature extends from the top or bottom surface and is positioned at a location away from the at least one lateral edge; and
the front surface and the rear surface of the main body are defined between the top and bottom surfaces, the front surface is continuous with both the top and bottom surfaces, the front surface is tapered to define a leading edge and a height of the leading edge is less than a height of the rear surface.

US Pat. No. 11,065,038

FRACTURE REDUCTION USING IMPLANT BASED SOLUTION

Medos International Sarl,...


1. A method for reducing and stabilizing fractures in a vertebra, comprising:positioning first and second rods within first and second receiver heads coupled to first and second bone screws implanted on opposed lateral sides of a vertebra;
manipulating the first and second receiver heads relative to the first and second rods and manipulating the first and second rods relative to an articulating joint coupling the first and second rods to thereby move at least one fracture formed in the vertebra into a reduced position; and
locking the first and second receiver heads to the first and second rods, and locking the articulating joint formed between the first and second rods to thereby prevent movement of the first and second receiver heads and the first and second rods, thereby maintaining the at least one fracture in the reduced position.

US Pat. No. 11,065,037

SPINAL CURVATURE MODULATION SYSTEMS AND METHODS

Auctus Surgical, Inc., S...


32. A spinal curve modulation system for treating spinal curvature along a treatment region of the spine, comprising:a flexible tether of sufficient length to extend across the treatment region of the spine including across at least three adjacent vertebral bodies in a cranial-caudal direction;
at least one first bone anchor including a tether attachment means;
a transcutaneously actuatable rotary drive;
a tether receiving spool rotatable around a rotation axis and operatively linked to the rotary drive to adjust tension in the flexible tether, the rotary drive and tether receiving spool comprising a tether tensioning unit;
at least one second bone anchor having a longitudinal axis configured to be attached to the tether tensioning unit after placement of the second bone anchor in a vertebra to anchor the rotary drive and tether receiving spool to the vertebra across the treatment region from at least one said first bone anchor; and
a transcutaneous actuator configured to actuate said rotary drive transcutaneously.

US Pat. No. 11,065,036

INSTRUMENT PORT FOR MINIMALLY INVASIVE CARDIAC SURGERY

Massachusetts Institute o...


1. An instrument port for introducing an instrument into a surgical site, the instrument port comprising:a port body including a body channel extending therethrough from a proximal end to a distal end of the port body;
an instrument sleeve in slidable contact with the body channel and having an instrument channel configured to receive the instrument, the instrument sleeve removably sealed within the port body,
wherein an outer surface of the instrument sleeve and an inner surface of the port body define a fluid gap within the body channel, and
wherein a flood line is defined in the fluid gap between the outer surface of the instrument sleeve and the inner surface of the port body;
a transparent bulb at the distal end of the port body; and
an imaging system at the distal end of the port body within the transparent bulb, wherein the imaging system comprises an imaging device and an illumination device.

US Pat. No. 11,065,035

MULTI-MODAL SURGICAL GAS CIRCULATION SYSTEM FOR CONTROLLING A NETWORK OF GAS SEALED ACCESS DEVICES

Conmed Corporation, Utic...


1. A system for performing an endoscopic surgical procedure in a surgical cavity, comprising:a) a primary gas circulation device housing a primary pump configured to deliver a flow of pressurized gas to a primary gas delivery lumen and to receive gas from a primary gas return lumen;
b) a primary gas sealed access port configured to receive pressurized gas from the primary gas delivery lumen to generate a gaseous seal therein and to return gas used to generate the gaseous seal back to the primary pump through the primary gas return lumen, so as to maintain a stable pressure level within the surgical cavity, wherein the primary gas sealed access port is a dual lumen gas sealed access port that includes coaxially arranged inner and outer tubular body portions defining an annular insufflation passage therebetween to accommodate delivery of insufflation gas into the surgical cavity, and wherein the inner tubular body portion is configured to accommodate gas sealed passage of a surgical instrument into the surgical cavity;
c) at least one subordinate gas circulation device, separate from, in communication with and controlled by the primary gas circulation device and housing a subordinate pump configured to deliver a flow of pressurized gas to a subordinate gas delivery lumen and to receive gas from a subordinate gas return lumen; and
d) at least one subordinate gas sealed access port configured to receive pressurized gas from the subordinate gas delivery lumen to generate a gaseous seal therein and to return gas used to generate the gaseous seal back to the subordinate pump through a subordinate gas return lumen, wherein the at least one subordinate gas sealed access port is a single lumen gas sealed access port that includes a single tubular body portion configured to accommodate gas sealed passage of another surgical instrument into the surgical cavity, and wherein the subordinate pump housed in the at least one subordinate gas circulation device is configured to provide only enough output power to generate the gaseous seal in the single lumen gas sealed access port.

US Pat. No. 11,065,034

MODULAR AUTOMATIC HAIR IMPLANTER

Electronics and Telecommu...


5. A modular automatic hair implanter comprising:a needle module, comprising a needle having a hollow shape, configured to accommodate a hair follicle;
a magazine in which the needle module is mounted; and
an operating unit configured to press the needle module mounted in the magazine to insert the hair follicle into a scalp, wherein the magazine comprises;
a magazine case having a cylindrical shape;
a magazine body mounted in the magazine case and having a rotation mounting hole formed at a center thereof and a module slit formed on an edge thereof in a circumferential direction, the needle module being mounted in the module slit;
a magazine front side part mounted on a front side of the magazine body and having a needle discharge hole formed an edge portion thereof so that the needle discharged from the needle module mounted on the module slit is discharged to an outside; and
a magazine rotating part mounted on a rear side of the magazine body and configured to rotate the magazine body using a rotational force transmitted from the operating unit,
wherein the magazine front side part comprises a front lid having a circular plate shape and formed with at least one through hole, which is a portion corresponding to the module slit, and a rotation shaft having one end supported by the front lid and another end fixed to the magazine body.

US Pat. No. 11,065,033

MINIMALLY INVASIVE SUBDURAL EVACUATING SYSTEM

MUSC Foundation for Resea...


1. A minimally invasive subdural evacuating system, comprising:a port having a distal threaded end and a lumen extending between a proximal opening and a distal opening;
an inner cannula having a distal cutting end, a lumen extending between a proximal opening and a distal opening, and an outer diameter sized to fit within the lumen of the port; and
an indicator rod having a distal blunt end and an outer diameter sized to fit within the lumen of the inner cannula;
wherein the indicator rod is configured to indicate the position of the system relative to a subject's skull and dura mater.

US Pat. No. 11,065,032

LIGHTING AND OPTICS SURGICAL SYSTEM

City of Hope, Duarte, CA...


1. A laparoscopic surgical system, comprising:elongated body sized and shaped to fit through an incision into a patient's body pursuant to a laparoscopic procedure;
a hub on a proximal end of the elongate body;
a light source attached to the body, the light source configured to transmit light at least along a longitudinal axis of the elongated body;
a plurality of mirrors positioned at the distal region of the elongated body wherein at least one mirror of the plurality of mirrors is pivotably attached to the elongated body such that the at least one mirror can rotate relative to the elongated body; and
a power source directly attached to the elongated body, wherein the power source provides power to the light source such that, when illuminated, the light source generates light that reflects off of at least one mirror of the plurality of mirrors in a distal direction;
wherein the elongated body does not include any tethers that attach to a remote power source or light source.

US Pat. No. 11,065,031

SYSTEMS AND METHODS FOR ASSEMBLING TISSUE GRAFTS

The General Hospital Corp...


1. A method for assembling a plurality of micro tissue grafts, the method comprising:a) harvesting the plurality of micro tissue grafts from a donor site;
b) arranging the plurality of micro tissue grafts in a desired orientation, wherein step b) includes placing the plurality of micro tissue grafts in a solution and inducing the plurality of micro tissue grafts to organize in the desired orientation;
c) forming a tissue construct containing the plurality of micro tissue grafts arranged in the desired orientation;
d) applying the tissue construct to a recipient site; and
further comprising applying a coating over a surface of the donor site so that an upper surface of each of the plurality of micro tissue grafts contains the coating.

US Pat. No. 11,065,030

ATHERECTOMY SYSTEM

BOSTON SCIENTIFIC LIMITED...


1. An atherectomy device, comprising:a housing;
a drive mechanism positioned within the housing and configured to couple to an elongate member and rotate the elongate member upon actuation;
a knob assembly in communication with the drive mechanism and operably accessible from exterior the housing, the knob assembly comprises:a slide adaptor coupled to the drive mechanism;
an actuator configured to be actuated to selectively adjust the drive mechanism between an on mode and an off mode;
a knob body coupled to the slide adaptor and the actuator, the knob body is configured to:releasably engage the housing to fix the drive mechanism at an axial location along the housing, and
rotate relative to the slide adaptor and the actuator; and


wherein the knob assembly is configured to longitudinally translate to adjust an axial position of the drive mechanism.

US Pat. No. 11,065,029

EXPANDABLE BALLOON

VERYAN MEDICAL LIMITED, ...


1. An expandable balloon for insertion in a vessel of the human or animal body, the balloon being movable between a collapsed condition and an expanded condition to expand the vessel, wherein a plaque disrupting member is disposed on an outer surface of the balloon when in the expanded condition, the plaque disrupting member extending over a lengthwise portion of the balloon, and the balloon having, when in the expanded condition, a centre line which follows a substantially helical path, wherein the plaque disrupting member is arranged helically on the balloon outer surface with substantially the same pitch as a helical centre line of the balloon, and wherein the plaque disrupting member is fixed at one end thereof relative to the balloon outer surface and is not attached to the balloon outer surface over a lengthwise extending portion of the balloon and, wherein the plaque disrupting member comprises a holder at its other end which is movable relative to the balloon outer surface.

US Pat. No. 11,065,028

METHOD AND APPARATUS FOR PLACING A CATHETER WITHIN A VASCULATURE

ROXWOOD MEDICAL INC., Re...


1. A method for positioning a catheter close to an occlusion in a vasculature, the method comprising:inserting a catheter apparatus into the vasculature, the catheter apparatus having a microcatheter, an outer shaft and a non-occluding self-expandable scaffold;

tracking the catheter apparatus along a guidewire located in proximity to the occlusion;
contacting a leading edge of the occlusion with a distal tip of the outer shaft;centering the microcatheter and the non-occluding self-expandable scaffold within the vasculature by expanding the non-occluding self-expandable scaffold within the vasculature;
advancing the guidewire and the microcatheter out of the distal tip through the occlusion;
withdrawing the microcatheter and the non-occluding self-expandable scaffold through a proximal opening in the outer shaft, wherein, after withdrawing the microcatheter and non-occluding self-expandable scaffold, the outer shaft remains near the occlusion in the vasculature; and
advancing an instrument through the proximal opening of the outer shaft and through the occlusion.

US Pat. No. 11,065,027

METHOD AND APPARATUS FOR TISSUE COPYING AND GRAFTING

The General Hospital Corp...


1. An apparatus for grafting at least one biological tissue, comprising:at least one hollow tube comprising at least two points or extensions provided at a distal end thereof,
wherein an inner diameter of the at least one hollow tube is less than about 1 mm,
wherein the at least one hollow tube comprises a biodegradable material,
wherein at least one section of the at least one hollow tube is structured to be inserted into the at least one biological tissue at a donor site to remove at least one portion of a graft tissue therefrom when the at least one section of the at least one hollow tube is withdrawn from the donor site, and
wherein the at least one hollow tube comprises a notch provided in a wall of the at least one hollow tube, wherein the notch is structured to facilitate breakage of the at least one hollow tube at a location of the notch, and wherein at least one section of the at least one hollow tube is structured to be inserted into a recipient site and subsequently broken off in the recipient site at the location of the notch to thereby place the at least one portion of the graft tissue within the recipient site.

US Pat. No. 11,065,026

DOUBLE EDGED BLADE GRIP ASSEMBLY

ACCUTEC, INC., Verona, V...


1. A double edged blade assembly, comprising:a double edged blade; and
two separate blade grips, the two blade grips being coupled to the double edged blade at opposite ends of the double edged blade with no direct connection between the two blade grips;
wherein each blade grip includes a body having a curved grip side with a plurality of teeth and a coupling side interacting with the double edged blade, each of the plurality of teeth extending from a base and terminating at a free end, the coupling side generally lying in a horizontal plane, the base of each of the plurality of teeth being wholly offset from the horizontal plane in a direction opposite the double edged blade, the plurality of teeth each being angled outwardly, away from the horizontal plane, in a direction from the respective base to the respective free end.

US Pat. No. 11,065,025

PROBE, TREATMENT INSTRUMENT AND TREATMENT DEVICE

OLYMPUS CORPORATION, Tok...


1. A treatment instrument comprising:a probe including:an elongated main body that is configured to transmit ultrasonic vibration, and
an engagement member that is provided on an outer circumference of a position of the main body and/or in the vicinity of the outer circumference of the position of the main body,the position of the main body becoming a node of the ultrasonic vibration when the ultrasonic vibration is transmitted to the main body, and
the engagement member being formed by a material of an identical to or smaller damping rate than a damping rate of the ultrasonic vibration in the main body; and


an exterior member that includes a holder engaged with the engagement member and that is disposed on an outer side of the main body,the holder being configured to regulate movement of the engagement member in an axial direction of a longitudinal axis of the main body with respect to the holder, and being configured to regulate rotation of the engagement member in a direction around the longitudinal axis.


US Pat. No. 11,065,023

ARTHROSCOPIC DEVICES AND METHODS

Relign Corporation, Camp...


1. A medical device for removing tissue in a patient, comprising:an elongated outer sleeve having a distal cut-out; and
a ceramic cutting member rotatably disposed in the elongated outer sleeve for exposure in the distal cut-out, the ceramic cutting member having a longitudinal axis that extends between a proximal end and a distal end of the ceramic cutting member,
wherein a cutting window with at least a first sharp window cutting edge is formed in the ceramic cutting member, the first sharp window cutting edge including a distal end and a proximal end and being configured to cut soft tissue as the cutting member is rotated or rotationally oscillated and engaged against soft tissue; and
wherein at least a first flute with a first burr cutting edge is formed in the ceramic cutting member, the first burr cutting edge including a distal end and a proximal end and being configured to cut bone as the cutting member is rotated or rotationally oscillated and engaged against bone, wherein the first burr cutting edge is circumferentially spaced-apart from the first sharp window cutting edge around the ceramic cutting member with the first burr cutting edge extending at least partially alongside the first sharp window cutting edge in an axial direction along the ceramic cutting member, the proximal end of the first burr cutting edge extending proximally of the distal end of the first sharp window cutting edge in the axial direction along the ceramic cutting member.

US Pat. No. 11,065,022

CUTTING MEMBER FOR A SURGICAL INSTRUMENT

Covidien LP, Mansfield, ...


1. A surgical instrument, comprising:an end effector having a proximal end and a distal end, the end effector including a first jaw and a second jaw;
a drive beam disposed inside the end effector and slidably attached to the first jaw, the drive beam includes a cut-out defining a first surface, a second surface, and a vertical strut, the first and second surfaces opposing each other;
a first blade attached to the vertical strut and including a first cutting edge extending linearly from the first surface to the second surface such that the first cutting edge defines an acute angle with respect to the vertical strut; and
a second blade attached to the first blade and the second surface such that the second blade is in contact with the first cutting edge of the first blade.

US Pat. No. 11,065,021

OSTEOTOMY DEVICE


1. An osteotomy system comprising: an aspiration system, an image-acquisition system, an irrigation system, an illumination system, a removable cutting instrument, and a tissue-protection catheter, wherein the aspiration system, the irrigation system and the cutting instrument are sheathed in the tissue-protection catheter, the tissue-protection catheter including: an elongate cylinder having a single protection lumen, a distal hole at a distal end portion, a proximal hole, at least one side-slit spaced from the distal end portion, and a handle, the side slit have a recessed region forming a tissue shielding area to shield the tissue within the slit and receive a tip of the cutting instrument, the slit open during insertion and cutting using the cutting instrument, and the cylinder having a substantially constant outer diameter along a length of the cylinder, the cylinder extending about a curve: wherein said handle comprises at least three ports, and wherein said handle is detachable from said elongate cylinder; and a first and second camera disposed along said cylinder, the second camera positioned proximal of the first camera and the first camera is distal of the side slit and positioned adjacent the distal hole of the cylinder, wherein the second camera extends from an external surface of the elongate cylinder and terminates proximal of a proximal wall of the recessed region, wherein the second camera is spaced from the first camera along the curve of the cylinder such that a length between the first and second cameras is defined along a non-linear path.

US Pat. No. 11,065,020

SUCTION CATHETER, SUCTION SYSTEM, AND TREATMENT METHOD

TERUMO KABUSHIKI KAISHA, ...


1. A method for suctioning an object in a blood vessel, the method comprising:inserting an expansion portion connected to a shaft portion on a distal portion of the shaft portion into the blood vessel;
expanding the expansion portion in the blood vessel;
inserting a suction catheter along the shaft portion into the blood vessel;
reciprocating at least the expansion portion or the suction catheter relative to each other along an axial axis of the shaft portion;
breaking the object by a proximal side coupling portion of the expansion portion and the suction catheter; and
suctioning the object with the suction catheter.

US Pat. No. 11,065,019

ASPIRATION CATHETER SYSTEMS AND METHODS OF USE

Route 92 Medical, Inc., ...


1. An intravascular catheter advancement device for advancing a catheter within the neurovasculature, the catheter advancement device comprising:a flexible elongate body having a proximal end, a distal end, and a single lumen extending therebetween, the flexible elongate body comprising:a proximal segment, wherein the proximal segment comprises a hypotube coated with a polymer;
an intermediate segment comprising an unreinforced polymer having a durometer of no more than 72 D; and
a tip segment, wherein the tip segment is formed of a polymer different from the intermediate segment and has a durometer of no more than about 35 D and a length of at least 5 cm, wherein the tip segment has a tapered portion that tapers distally from a first outer diameter to a second outer diameter over a length of between 1 and 3 cm,

wherein the catheter advancement device has a length configured to extend from outside a patient's body, through a femoral artery, and to a petrous portion of an internal carotid artery and an inner diameter less than 0.024 inches to accommodate a guidewire.