US Pat. No. 10,689,359

CRYSTALS OF QUINAZOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR

Xuanzhu Pharma Co., Ltd.,...

1. Crystal form I of N-(4-((3-chloro-4-fluorophenyl)amino)-7-((7-methyl-7-azaspiro[3.5]nonan-2-yl)methoxy)quinazolin-6-yl)acrylamide represented by Formula (I), wherein the Crystal form I exhibits an X-ray powder diffraction pattern having characteristic peaks at the 2? positions of 6.7±0.2°, 7.9±0.2°, 8.6±0.2°, 12.0±0.2°, 13.9±0.2°, 15.9±0.2°, 17.3±0.2°, 18.3±0.2°, 18.7±0.2°, 21.0±0.2°, and 23.0±0.2°, as determined by using Cu-K? radiation,

US Pat. No. 10,689,358

METHOD FOR PRODUCING INDAZOLE COMPOUND, AND INDAZOLE COMPOUND

FUJIFILM Corporation, To...

1. A method for producing an indazole compound, comprising obtaining an indazole compound represented by the following General Formula (3) or a salt thereof from a diazonium salt prepared from an aniline compound represented by the following General Formula (2) in the presence of a compound represented by the following General Formula (1),
in the formula,
R1 represents a hydrogen atom or an alkali metal;
R2 represents a hydrogen atom, a hydroxyl group, an amino group, a mercapto group, a C1-6 alkyl group which may have a substituent, a C3-8 cycloalkyl group which may have a substituent, a C1-6 alkoxy-C1-6 alkyl group which may have a substituent, a C6-20 aryl-C1-6 alkyl group which may have a substituent, a C1-6 alkoxy group which may have a substituent, a C6-20 aryloxy group which may have a substituent, a C1-6 alkylamino group which may have a substituent, a C6-20 arylamino group which may have a substituent, a C1-6 alkylthio group which may have a substituent, a C6-20 arylthio group which may have a substituent, a C2-6 alkenyl group which may have a substituent, a C3-8 cycloalkenyl group which may have a substituent, a C2-6 alkynyl group which may have a substituent, a C6-20 aryl group which may have a substituent, or a heterocyclic group which may have a substituent; and
R3 represents a hydrogen atom, a C1-30 alkylcarbonyl group which may have a substituent, or a C6-20 arylcarbonyl group which may have a substituent,

in the formula,
X represents a C1-6 alkyl group which may have a substituent, a C3-8 cycloalkyl group which may have a substituent, a C1-6 alkoxy-C1-6 alkyl group which may have a substituent, a C6-20 aryl-C1-6 alkyl group which may have a substituent, a C2-6 alkenyl group which may have a substituent, a C2-6 alkynyl group which may have a substituent, a C6-20 aryl group which may have a substituent, or a heterocyclic group which may have a substituent;
Y's each independently represent a halogen atom, a carboxyl group, a hydroxyl group, an amino group, a mercapto group, a C1-6 alkyl group which may have a substituent, a C3-8 cycloalkyl group which may have a substituent, a C1-6 alkoxy-C1-6 alkyl group which may have a substituent, a C6-20 aryl-C1-6 alkyl group which may have a substituent, a C1-6 alkoxy group which may have a substituent, a C6-20 aryloxy group which may have a substituent, a C1-6 alkylamino group which may have a substituent, a C6-20 arylamino group which may have a substituent, a C1-6 alkylthio group which may have a substituent, a C6-20 arylthio group which may have a substituent, a C2-6 alkenyl group which may have a substituent, a C3-8 cycloalkenyl group which may have a substituent, a C2-6 alkynyl group which may have a substituent, a C6-20 aryl group which may have a substituent, or a heterocyclic group which may have a substituent; and
n is an integer from 0 to 4; and in a case in which n is 2 or greater, a plurality of existing Y's may be identical with or different from one another, and

in the formula, X, Y, and n have the same meanings as those described above.

US Pat. No. 10,689,357

N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND USE THEREOF

NORTHEASTERN UNIVERSITY, ...

1. A compound represented by the following structural formula:
or a pharmaceutically acceptable salt thereof, wherein:
Ring A is absent, cycloalkyl, aryl, heterocyclyl or heteroaryl;
V is absent, —O—, —N(R10)—, —S(O)2—, —S(O)—, —C(O)—, —C(O)N(R10)— or —C(R11)(R12);
R10 is —H or C1-C4 alkyl;
R11 and R12 are each independently —H, C1-C4 alkyl, cycloalkyl, aryl, heterocyclyl or heteroaryl, or taken together with the carbon atom to which they are attached, form a saturated or unsaturated ring;
B is C1-C6 alkylene, C1-C6 alkenylene, C1-C6 alkynylene, cycloalkylene, arylene, heterocyclylene or heteroarylene;
Y is —C(O)N(R13)—, —C(O)O—, —S(O2)N(R13)—, —S(O2)O—, —P(O)(R14)N(R13)—, —P(O)(R14)O—, —OC(O)N(R13)—, —OC(O)O— or —N(R13)C(O)N(R13)—;
each R13 is independently —H or C1-C4 alkyl;
R14 is C1-C4 alkyl; and
Ring D is C3-C7 cycloalkyl.

US Pat. No. 10,689,356

INHIBITORS OF KRAS G12C MUTANT PROTEINS

ARAXES PHARMA LLC, San D...

1. A compound having one of the following structures (Ia?), (Ib?) or (Ic?):or a pharmaceutically acceptable salt, tautomer, stereoisomer or prodrug thereof, wherein:G2? G3 and G4 are each independently N or CR, where R is H, cyano, halo or C1-C6 alkyl;
R1 is phenyl;
R2a and R2b are independently H or hydroxyl;
R3a is H;
R3b is, at each occurrence, independently H, —OH, —NH2, —CO2H, halo, cyano, C1-C6 alkyl, C2-C6 alkynyl, hydroxylalkly, aminylalkyl, alkylaminylalkyl, cyanoalkyl, carboxyalkyl, aminocarbonylalkyl or aminocarbonyl;
R4a is H;
R4b is, at each occurrence, independently H, —OH, —NH2, —CO2H, halo, cyano, C1-C6 alkyl, C2-C6 alkynyl, hydroxylalkly, aminylalkyl, alkylaminylalkyl, cyanoalkyl, carboxyalkyl, aminocarbonylalkyl or aminocarbonyl;
L1 is a bond;
L2 is a linker of one, two or three atoms in length, the linker comprising carbon or nitrogen atoms, or combinations thereof;
m1 and m2, are each independently 1 or 2;
m3 and m4 are each independently 1, 2 or 3;
Q is —C(?O)—;
R7 is H, —OH, —CN or C1-C6 alkyl;
R8 is H, C1-C6 alkyl or hydroxylalkyl;
represents a double bond; and
R9 and R10 are each H,
wherein all valences are satisfied.

US Pat. No. 10,689,355

ANTICANCER AGENT

Kyoto Pharmaceuticals Ind...

1. A production method of a compound represented by formula (Ia):or a pharmaceutically acceptable salt thereof,whereineach R1 is independently
hydrogen
halogen
hydroxy,
amino,
cyano,
nitro,
C1-12 alkyl,
C2-6 alkenyl,
C2-6 alkynyl,
C3-7 cycloalkyl,
C3-7 cycloalkenyl,
aryl,
heterocyclyl group,
C1-6 alkoxy,
aryloxy,
C1-6 alkylthio, or
arylthio, or
two R1 bonded to the adjacent carbon atoms on a benzene ring are optionally joined to form C1-4 alkylenedioxy,
R2 is
C1-12 alkyl optionally substituted by substituent(s) selected from substituent group ?,
C2-6 alkenyl optionally substituted by substituent(s) selected from substituent group ?,
C2-6 alkynyl optionally substituted by substituent(s) selected from substituent group ?,
C3-7 cycloalkyl optionally substituted by substituent(s) selected from substituent group ?,
aryl optionally substituted by substituent(s) selected from substituent group ?,
aryl C1-6 alkyl optionally substituted by substituent(s) selected from substituent group ?, or
heterocyclyl optionally substituted by substituent(s) selected from substituent group ?,
n is an integer of 1-4 when R1 is hydrogen,
n is an integer of 1 or 2 when R1 is not hydrogen, and
the substituent group ? consists of
halogen,
hydroxy,
optionally substituted amino,
carboxy,
C1-6 alkoxycarbonyl,
sulfo group,
phosphoric acid group,
di C1-6 alkyl phosphoric acid group,
cyano,
optionally substituted C1-6 alkyl,
C3-7 cycloalkyl,
C3-7 cycloalkyl C1-6 alkyl,
optionally substituted C1-6 alkoxy,
C1-6 alkylthio,
optionally substituted aryl,
optionally substituted aryloxy,
aryl C1-6 alkoxy,
optionally substituted heterocyclyl,
optionally substituted C1-6 alkylcarbonyl,
heterocyclylcarbonyl,
optionally substituted C1-6 alkylcarbonyloxy,
optionally substituted C3-7 cycloalkylcarbonyloxy,
arylcarbonyloxy,
monocyclic heterocyclylcarbonyloxy,
optionally substituted C1-6 alkoxycarbonyloxy,
optionally substituted heterocyclyl C1-6 alkoxycarbonyloxy,
C3-7 cycloalkyloxycarbonyloxy,
heterocyclyloxycarbonyloxy,
optionally substituted heterocyclyloxy,
tri C1-6 alkylammonio,
optionally substituted C1-6 alkylsulfonyl and
C1-6 alkylsulfamoylcarbonyl,comprisinga step of reacting a compound represented by the formula (2):
or a salt thereof, wherein X is halogen, and R1 is as defined for R2 in said formula (Ia), in inert solvent in the presence of a base and a compound represented by the formula (3):or a salt thereof, wherein R2 is as defined for R2 in said formula (Ia).

US Pat. No. 10,689,354

AMINOAZOLE DERIVATIVE

Teijin Pharma Limited, C...

14. A compound represented by any one of the following chemical formula:

US Pat. No. 10,689,353

METHOD FOR THE MANUFACTURE OF EFAVIRENZ

NELSON MANDELA METROPOLIT...

1. A method for the manufacture of (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one of formula 8
comprising the steps of:
a) preparing tert-butyl-4-chloro phenyl carbamate of formula 26

by reacting 4-chloroaniline with di-tert-butyl dicarbamate,
b) reacting the tert-butyl-4-chloro phenyl carbamate of formula 26 with butyllithium and piperidine trifluoroacetic acid of formula 67

in a trifluroacetylation reaction to produce tert-butyl-4-chloro-2-(2,2,2-trifluoroacetyl) phenyl carbamate of formula 27

c) reacting the compound of formula 27 with cyclopropyl acetylene of formula 53 and (1R,2S) N-pyrrolidinylnorephedrine of formula 60

in the presence of butyllithium to produce (S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol of formula 56

d) reacting the compound of formula 56 with a compound of the formula 70

in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene to produce (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one of formula 8,
wherein the method is a flow synthesis method.

US Pat. No. 10,689,351

ISOTOPOLOGUES OF 2-(TERT BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE

Signal Pharmaceuticals, L...

1. A compound, wherein the compound is a compound having the following structure:or a pharmaceutically acceptable salt, stereoisomer or solvate thereof,wherein one or more of Y1, Y2, Y3, Y4, Y5, Y6, Y7, Y8, Y9, Y10, Y11, Y12, Y13, Y14, Y15, Y16, Y17, Y18, Y19, Y20, Y21, and Y22 is a hydrogen that is isotopically enriched with deuterium, and the others of Y1, Y2, Y3, Y4, Y5, Y6, Y7, Y8, Y9, Y10, Y11, Y12, Y13, Y14, Y15, Y16, Y17, Y18, Y19, Y20, Y21, and Y22 are non-enriched hydrogen atoms.

US Pat. No. 10,689,350

METHOD FOR PREPARATION OF CHLORINATED S-PROPYLTHIOBARBITURIC ACID

LONZA LTD, Visp (CH)

1. Method for the preparation of compound of formula (2)
by a reaction REAC1 of compound of formula (1)

with a compound PHOS in the presence of DMF;
PHOS is selected from the group consisting of phosgene, diphosgene, triphosgene and mixtures thereof.

US Pat. No. 10,689,349

METHOD FOR PRODUCING INTERMEDIATE OF BIOTIN AND METHOD FOR PRODUCING BIOTIN

Tokuyama Corporation, Ya...

1. A method for producing a lactone compound in which an ureido compound represented by the following formula (11)
wherein, R1 and R2 may be the same or different and represent a hydrogen atom or a protecting group of an ureylene group, is dehydrated by refluxing in a reaction solvent comprising mesitylene, thereby producing an anhydride compound represented by the following formula (7)

the anhydride compound and an optically active amine compound represented by the following formula (8)

wherein, R4 represents an alkyl group, an aralkyl group, or an aryl group, and each of R5, R6, and R7 represents a hydrogen atom, an alkyl group, an alkoxy group, or a halogen atom, are reacted in a reaction solvent comprising mesitylene, thereby producing a mixture which comprises an amide compound I represented by the following formula (9)

and an amide compound II represented by the following formula (10)

a first reaction solution comprising the obtained mixture and mesitylene is refluxed to dehydrate the mixture, thereby producing a trione compound represented by the following formula (1)

the trione compound is (ii) reduced by calcium borohydride in ethanol, thereby producing an amide alcohol compound represented by the following formula (3)

and the amide alcohol compound is cyclized in the presence of hydrogen chloride in a solvent comprising an alkylene glycol monoalkyl ether in which the total number of carbon atoms in a molecule is 2 to 12, thereby producing a lactone compound represented by the following formula (4)

US Pat. No. 10,689,348

HETEROCYCLIC COMPOUNDS AS PESTICIDES

Bayer Cropscience AG, Mo...

1. A compound of formula (I)
wherein
A represents

 in which the broken line represents the bond to Q and in which A furthermore carries m substituents R2,
Q represents

 in which the nitrogen is attached to ring A and the arrow represents the bond to D and
D represents the radical of the formula

 in which the nitrogen is attached to Q and the arrow represents the bond to B,
B represents

 in which the broken line represents the bond to D and in which B furthermore carries n substituents R7,
Z represents oxygen or sulphur,
R2 represents a radical from the group consisting of halogen, cyano, nitro, amino, hydroxy, represents C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl, C1-C6-alkoxy, C3-C6-alkenoxy, C3-C6-alkynoxy, C3-C6-cycloalkoxy, C1-C6-alkylcarbonyloxy, C2-C6-alkenylcarbonyloxy, C2-C6-alkynylcarbonyloxy, C3-C6-cycloalkylcarbonyloxy, C1-C6-alkoxycarbonyloxy, C1-C6-alkylsulphonyloxy, C1-C6-alkylamino, di-(C1-C6-alkyl)-amino, C1-C6-alkenylamino, C3-C6-alkynylamino, C3-C6-cycloalkylamino, C3-C6-alkylcarbonylamino, C1-C6-alkenylcarbonylamino, C2-C6-alkynylcarbonylamino, C3-C6-cycloalkylcarbonylamino, C1-C6-alkoxycarbonylamino, C1-C6-alkylsulphonylamino, C1-C6-alkylthio, C3-C6-alkenylthio, C3-C6-alkynylthio, C3-C6-cycloalkylthio, C1-C6-alkylsulphinyl, C1-C6-alkylsulphonyl, C1-C6-alkylcarbonyl, C1-C6-alkoxyimino-C1-C6-alkyl, C1-C6-alkoxycarbonyl, aminocarbonyl, C1-C6-alkylaminocarbonyl, di-(C1-C6-alkyl)-aminocarbonyl, aminothiocarbonyl, C1-C6-alkylaminosulphonyl, C1-C6-alkylsulphonylamino, C1-C6-alkylcarbonylamino, C1-C6-alkylthiocarbonylamino, C4-C12-bicycloalkyl, aryl, aryloxy, arylamino, arylthio, each of which is optionally substituted by one or more identical or different substituents, where the substituents independently of one another are selected from the group consisting of halogen, cyano, nitro, hydroxy, amino, C1-C6-alkyl, C1-C6-alkoxy, C3-C6-cycloalkyl, C1-C6-haloalkoxy and C1-C6-alkylthio, aryl, aryloxy, and arylthio,
R3 represents a radical from the group consisting of hydrogen, halogen, cyano, nitro, amino, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl and C1-C6-haloalkoxy,
R4 represents a radical from the group consisting of hydrogen, halogen, amino, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl and C1-C6-haloalkoxy,
R5 represents a radical from the group consisting of hydrogen, C1-C6-alkyl, C3-C6-cycloalkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C3-C6-alkynyl, C3-C6-cycloalkyl-C1-C6-alkyl, cyano-C1-C6-alkyl, C1-C6-alkylcarbonyl, C2-C6-alkenylcarbonyl, C1-C6-haloalkylcarbonyl, C2-C6-haloalkenylcarbonyl, C1-C6-alkoxy-C1-C6-alkyl, C1-C6-alkoxycarbonyl, C1-C6-alkylsulphonyl and C1-C6-haloalkylsulphonyl or represents C(?O)—B,
R6 represents a radical from the group consisting of halogen, cyano, nitro, amino, hydroxy, carboxyl, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl, C1-C6-alkoxy, C3-C6-alkenoxy, C3-C6-alkynoxy, C3-C6-cycloalkoxy, C1-C6-alkylcarbonyloxy, C2-C6-alkenylcarbonyloxy, C2-C6-alkynylcarbonyloxy, C3-C6-cycloalkylcarbonyloxy, C1-C6-alkoxycarbonyloxy, C1-C6-alkylsulphonyloxy, C1-C6-alkylcarbonylamino, C2-C6-alkenylcarbonylamino, C2-C6-alkynylcarbonylamino, C3-C6-cycloalkylcarbonylamino, C1-C6-alkoxycarbonylamino, C1-C6-alkylsulphonylamino, C1-C6-alkylthio, C1-C6-alkylsulphinyl, C1-C6-alkylsulphonyl, C1-C6-alkylcarbonyl, C1-C6-alkoxyimino-C1-C6-alkyl, C1-C6-alkoxycarbonyl, aminocarbonyl, C1-C6-alkylaminocarbonyl, di-(C1-C6-alkyl)-aminocarbonyl, aminothiocarbonyl, C1-C6-alkylaminosulphonyl, C1-C6-alkylsulphonylamino, C1-C6-alkylcarbonylamino, C1-C6-haloalkylcarbonylamino, C1-C6-alkylthiocarbonylamino, C4-C12-bicycloalkyl, aryl, aryloxy, each of which is optionally substituted by one or more identical or different substituents, where the substituents independently of one another are selected from the group consisting of halogen, cyano, nitro, hydroxy, amino, C1-C6-alkyl, C1-C6-alkoxy, C3-C6-cycloalkyl, C1-C6-haloalkoxy and C1-C6-alkylthio,
R7 represents a radical from the group consisting of halogen, nitro, cyano, amino, hydroxy, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl, C1-C6-alkoxy, C3-C6-alkenoxy, C3-C6-alkynoxy, C3-C6-cycloalkoxy, C1-C6-alkylcarbonyloxy, C2-C6-alkenylcarbonyloxy, C2-C6-alkynylcarbonyloxy, C3-C6-cycloalkylcarbonyloxy, C1-C6-alkoxycarbonyloxy, C1-C6-alkylsulphonyloxy, C1-C6-alkylcarbonylamino, C2-C6-alkenylcarbonylamino, C2-C6-alkynylcarbonylamino, C3-C6-cycloalkylcarbonylamino, C1-C6-alkoxycarbonylamino, C1-C6-alkylsulphonylamino, C1-C6-alkylthio, C1-C6-alkylsulphinyl, C1-C6-alkylsulphonyl, C1-C6-alkylcarbonyl, C1-C6-alkoxyimino-C1-C6-alkyl, C1-C6-alkoxycarbonyl, aminocarbonyl, C1-C6-alkylaminocarbonyl, di-(C1-C6-alkyl)-aminocarbonyl, aminothiocarbonyl, C1-C6-alkylaminosulphonyl, C1-C6-alkylsulphonylamino, C1-C6-alkylcarbonylamino, C1-C6-alkylthiocarbonylamino, aryl, aryloxy, C4-C12-bicycloalkyl, each of which is optionally substituted by one or more identical or different substituents, where the substituents independently of one another are selected from the group consisting of halogen, cyano, nitro, hydroxy, amino, C1-C6-alkyl, C1-C6-alkoxy, C3-C6-cycloalkyl, C1-C6-haloalkoxy and C1-C6-alkylthio,
m represents a number from the group consisting of 0, 1, 2 and 3, where for m>1 the radicals R2 may be identical or different and
n represents a number from the group consisting of 0, 1, 2 and 3, where for n>1 the radicals R7 may be identical or different.

US Pat. No. 10,689,347

SUBSTITUTED HETEROCYCLYL DERIVATIVES AS CDK INHIBITORS

Aurigene Discovery Techno...

1. A compound having the structure:
or a pharmaceutically acceptable salt, or an enantiomer thereof.

US Pat. No. 10,689,346

HUMAN PLASMA KALLIKREIN INHIBITORS

BioCryst Pharmaceuticals,...

1. A method of treating a disease or condition characterized by unwanted plasma kallikrein activity, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula II, or a pharmaceutically acceptable salt thereof:
wherein:
X represents CH, C(OH), C(O(C1-C6)alkyl), —C(NH2), —C(NRaRb), —C(N3), —C(CN), —C(NO2), —C(S(O)nRa), —C[—C(?O)Rc], —C[—C(?O)NRcRd], —C[—C(?O)SRc], —C[—S(O)Rc], —C[—S(O)2Rc], —C[S(O)(ORc)], —C[—S(O)2(ORc)], —C[—SO2NRcRd], —C(halogen), —C[(C1-C5)alkyl], —C[(C4-C5)carbocyclyl], —C[(C1-C8)substituted alkyl], —C[(C2-C8)alkenyl], —C[(C2-C8)substituted alkenyl], —C[(C2-C8)alkynyl], —C[(C2-C8)substituted alkynyl], —C[aryl(C1-C5)alkyl] or N;
—Y—R4 represents —((C1-C6)alkyl)-R4, —CH2C(O)—R4, —CH2NH-R4, —CH2N((C1-C6)alkyl)-R4, —CRaRb—R4, —NH—R4, —NHCH2—R4, —NHC(O)—R4, —N((C1-C6)alkyl)-R4, —N((C1-C6)alkyl)CH2—R4, —N((CH2)2OH)—R4, —N[(C3-C8)cycloalkyl(C1-C6)alkyl]R4, -heterocyclyl-R4, —OR4, —OCH2—R4, —OC(O)—R4, —SCH2R4, or —SR4, wherein the (C1-C6)alkyl moiety of —((C1-C6)alkyl)-R4 is optionally substituted;
Z is absent or represents one or more substituents independently selected from the group consisting of halo, hydroxy, (C1-C6)alkyl, —CF3, —OCF3, (C1-C6)alkoxy, aryl, aryloxy, amino, amino(C1-C6)alkyl, —C(O)NH2, cyano, —NHC(O)(C1-C6)alkyl, —SO2(C1-C6)alkyl, —SO2NH2, (C3-C5)cycloalkyl, (CH2)rORa, N02, (CH2)rNRaRb, (CH2)rC(O)Ra, NRaC(O)Rb, C(O)NRcRd, NRaC(O)NRcRd, —C(?NRa)NRcRd, NHC(?NRa)NRcRd, NRaRb, SO2NRcRd, NRaSO2NRcRd, NRaSO2-(C1-C6)alkyl, NRaSO2Ra, S(O)pRa, (CF2)rCF3, NHCH2Ra, OCH2Ra, SCH2Ra, NH(CH2)2(CH2)rRa, O(CH2)2(CH2)rRa, and S(CH2)2(CH2)rRa; or alternatively Z is a 5- or 6-membered aromatic heterocycle containing from 1 to 4 heteroatoms selected from the group consisting of N, O, and S;
R1c represents halo, amino(C1-C6)alkyl, (C1-C6)alkoxy, cyano, —C(?NH)NH2, —CONRaRb, —(C1-C6)alkylCONRaRb, —SO2CH3, formyl, acyl, —NH2, —C(?NH)NH(OH), —C(?NH)NH(C(O)O—(C1-C6)alkyl), —C(?NH)NH(C(O)O—(C1-C6)haloalkyl), —C(?NH)NH(C(O)S—(C1-C6)alkyl), —C(?NH)NH(C(O)(OCH(C1-C6)alkyl)OC(O)(C1-C6)alkyl), optionally substituted aryl, or optionally substituted heteroaryl;
R2 represents halo, (C1-C6)alkyl, (C3-C8)cycloalkyl, (C1-C6)fluoroalkyl, —OCH3, —Si(CH3)3, —CONH2, —C(O)OH, cyano, or phenyl;
R3 represents —NH—, —O—, optionally substituted aryl, heteroaryl, phenyl, carbocyclyl, or heterocyclyl;
R3a is absent or represents one or more substituents independently selected from the group consisting of halo, hydroxy, (C1-C6)alkyl, —CF3, —OCF3, (C1-C6)alkoxy, aryl, aryloxy, amino, amino(C1-C6)alkyl, —C(O)NH2, cyano, —NHC(O)(C1-C6)alkyl, —SO2(C1-C6)alkyl, —SO2NH2, (C3-C8)cycloalkyl, (CH2)rORa, NO2, (CH2)rNRaRb, (CH2)rC(O)Ra, NRaC(O)Rb, C(O)NRcRd, NRaC(O)NRcRd, —C(?NRa)NRcRd, NHC(?NRa)NRcRd, NRaRb, SO2NRcRd, NRaSO2NRcRd, NRaSO2-(C1-C6)alkyl, NRaSO2Ra, S(O)pRa, (CF2)rCF3, NHCH2Ra, OCH2Ra, SCH2Ra, NH(CH2)2(CH2)rRa, O(CH2)2(CH2)rRa, or S(CH2)2(CH2)rRa; or alternatively R3a is a 5- or 6-membered aromatic heterocycle containing from 1 to 4 heteroatoms selected from the group consisting of N, O, and S;
R4 represents hydrogen, hydroxy, optionally substituted (C1-C6)alkyl, optionally substituted (C3-C8)cycloalkyl, heterocyclyl(C1-C6)alkyl, (C3-C8)cycloalkyl(C1-C6)alkyl, —CH2OH, —CH((C1-C6)alkyl)OH, —CH(NH2)CH((C1-C6)alkyl)2, optionally substituted aryl, optionally substituted aryl(C1-C6)alkyl, heteroaryl, optionally substituted heteroaryl(C1-C6)alkyl, —CH2S(C1-C6)alkyl, amino, or cyano;
each Ra and Rb is independently H, (C1-C8)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, aryl(C1-C8)alkyl, (C3-C8)carbocyclyl, —C(?O)Rc, —C(?O)ORc, —C(?O)NRcRd, —C(?O)SRc, —S(O)Rc, —S(O)2Rc, —S(O)(ORc), or —SO2NRcRd;
each Rc and Rd is independently H, (C1-C8)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C4-C8) carbocyclyl, optionally substituted aryl, optionally substituted heteroaryl, —C(?O)(C1-C8)alkyl, —S(O)n(C1-C8)alkyl, or aryl(C1-C8)alkyl; or when R and Rd are bonded to a common nitrogen atom, then they may form a 3- to 7-membered heterocyclic ring wherein optionally a carbon atom of said heterocyclic ring may be replaced with —O—, —S— or —NRa—;
n is 2 or 3;
r is independently for each occurrence 0, 1, 2, or 3;
p is independently for each occurrence 0, 1, or 2; and
the stereochemical configuration at any chiral center is R, S, or a mixture of R and S.

US Pat. No. 10,689,345

1-CYANO-PYRROLIDINE COMPOUNDS AS USP30 INHIBITORS

Mission Therapeutics Limi...

1. A compound having the formula (II):
a tautomer thereof, or a pharmaceutically acceptable salt of said compound or tautomer,
wherein:
m is 0;
R2 represents a hydrogen atom or C1-C3 alkyl;
R3, R4 and R5 each independently represent a hydrogen atom, optionally substituted C1-C3 alkyl, or C1-C3 alkoxy group, wherein the optional substituents of alkyl of R3, R4 and R5, which may be the same or different, are selected from C1-C3 alkoxy, halogen, hydroxyl, thiol, cyano, amino, amido, nitro and SF5;
R1 and R8 each independently represent a hydrogen atom or C1-C3 alkyl;
R9 represents a hydrogen atom, a fluorine atom, hydroxyl, C1-C3 alkyl, C1-C3 alkoxy group, or cyclopropyl;
R10 represents a hydrogen atom;
Y represents a covalent bond;
R12 is a 5-membered heteroaryl ring, which comprises 1, 2 or 3 heteroatoms independently selected from nitrogen, oxygen and sulfur, which is substituted with one or more of -Q1-(R13)p, wherein:
p is 0 or 1;
Q1 is selected from halogen, cyano, oxo, a covalent bond, —NR14R15—, —NR14CO—, an oxygen atom, C1-C6 alkoxy, —NR14—, —NR14COR15, C1-C6 alkyl, C1-C3 alkylene, wherein the alkyl and alkoxy are optionally substituted with fluorine;
R14 and R15 each independently represent a hydrogen atom or C1-C3 alkyl;
when p is 1, R13 represents a 4 to 10-membered, monocyclic or bicyclic, heteroaryl or heterocyclyl ring, which comprises 1, 2 or 3 heteroatoms selected from nitrogen, oxygen and sulfur; or R13 represents phenyl, naphthyl, or a 3 to 8-membered cycloalkyl ring;
wherein R13 is optionally substituted with one or more substituents selected from halogen, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkyl, oxo, cyano, -Q2-R17, -Q2-COR17, Q2-CONR17R18, and -Q2-CO2R17;
Q2 represents a covalent bond or an oxygen atom; and
R17 and R18 each independently represent hydrogen, C1-C6 alkyl, cyclopropyl, phenyl, or a 4 to 10-membered, monocyclic or bicyclic, heterocyclyl or heteroaryl ring, which comprises 1, 2 or 3 heteroatoms selected from nitrogen, oxygen and sulfur; wherein said phenyl, heterocyclyl, or heteroaryl ring, may be optionally substituted with one or more substituents, which may be the same or different, selected from chloro and fluoro.

US Pat. No. 10,689,344

BIPHENYLAMIDE DERIVATIVE HSP90 INHIBITORS

UNIVERSITY OF KANSAS, La...

1. A compound selected from formulas I, II, III, or IV, whereinthe formulas are further defined as:

wherein:
X1 is heterocycloalkyl(C?12) or a substituted version thereof;
Y1 is cycloalkyl(C?18), aryl(C?24), heteroaryl(C?24), -arenediyl(C?18)-alkyl(C?8), -arenediyl(C?18)-alkenyl(C?8), -arenediyl(C?18)-alkoxy(C?8), or a substituted version of any of these groups;
R1 is hydrogen, alkyl(C?6), or substituted alkyl(C?6);
each R2 and R3 are each independently selected from hydrogen, amino, cyano, halo, hydroxy, mercapto, nitro, sulfato, sulfamido, alkyl(C?12), substituted alkyl(C?12), alkoxy(C?12), substituted alkoxy(C?12), acyl(C?12), substituted acyl(C?12), acyloxy(C?12), substituted acyloxy(C?12), amido(C?12), or substituted amido(C?12); and
x and y are each independently selected from 0, 1, 2, 3, or 4;

wherein:
X2 is heterocycloalkyl(C?12) or a substituted version thereof;
Y2 is cycloalkyl(C?18), aryl(C?24), heteroaryl(C?24), -arenediyl(C?18)-alkyl(C?8), -arenediyl(C?18)-alkenyl(C?8), -arenediyl(C?18)-alkoxy(C?8), or a substituted version of any of these groups;
R4 is hydrogen, alkyl(C?6), or substituted alkyl(C?6);
each R5 and R6 are each independently selected from hydrogen, amino, cyano, halo, hydroxy, mercapto, nitro, sulfato, sulfamido, alkyl(C?12), substituted alkyl(C?12), alkoxy(C?12), substituted alkoxy(C?12), acyl(C?12), substituted acyl(C?12), acyloxy(C?12), substituted acyloxy(C?12), amido(C?12), or substituted amido(C?12); and
x and y are each independently selected from 0, 1, 2, 3, or 4;

wherein:
X3 is heterocycloalkyl(C?12) or a substituted version thereof;
Y3 is cycloalkyl(C?18), aryl(C?24), heteroaryl(C?24), -arenediyl(C?18)-alkyl(C?8), -arenediyl(C?18)-alkenyl(C?8), -arenediyl(C?18)-alkoxy(C?8), or a substituted version of any of these groups;
R7 is hydrogen, alkyl(C?6), or substituted alkyl(C?6);
each R8 and R9 are each independently selected from hydrogen, amino, cyano, halo, hydroxy, mercapto, nitro, sulfato, sulfamido, alkyl(C?12), substituted alkyl(C?12), alkoxy(C?12), substituted alkoxy(C?12), acyl(C?12), substituted acyl(C?12), acyloxy(C?12), substituted acyloxy(C?12), amido(C?12), or substituted amido(C?12); and
x and y are each independently selected from 0, 1, 2, 3, or 4;

wherein:
X4 is heterocycloalkyl(C?12) or a substituted version thereof;
Y4 is cycloalkyl(C?18), aryl(C?24), heteroaryl(C?24), -arenediyl(C?18)-alkyl(C?8), -arenediyl(C?18)-alkenyl(C?8), -arenediyl(C?18)-alkoxy(C?8), or a substituted version of any of these groups;
R10 is hydrogen, alkyl(C?6), or substituted alkyl(C?6);
each R11 and R12 are each independently selected from hydrogen, amino, cyano, halo, hydroxy, mercapto, nitro, sulfato, sulfamido, alkyl(C?12), substituted alkyl(C?12), alkoxy(C?12), substituted alkoxy(C?12), acyl(C?12), substituted acyl(C?12), acyloxy(C?12), substituted acyloxy(C?12), amido(C?12), or substituted amido(C?12); and
x and y are each independently selected from 0, 1, 2, 3, or 4;
or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,689,343

INHIBITORS OF TRYPTOPHAN 2,3-DIOXYGENASE

NETHERLANDS TRANSLATIONAL...

1. A compound of Formula I:
or a pharmaceutically acceptable salt thereof wherein,
R1 is fluoro,
R2 is hydrogen,
R3 is selected from the group consisting of hydrogen and halogen,
R4 is selected from the group consisting of hydrogen, halogen and (1-6C)alkoxy,
R5 is selected from the group consisting of hydrogen and halogen,
R6 is selected from the group consisting of hydrogen and halogen,
A is

R7 is selected from the group consisting of:
a) hydroxy(1-6C)alkyl,
b) di[(1-6C)alkyl]amino(1-6C)alkyl,
c) (3-7C)cycloalkyl,
d) (2-7C)heterocycloalkyl(2-3C)alkyl, and
e) (2-7C)heterocycloalkyl,
R7 optionally being substituted with one or more groups selected from the group consisting of halogen, hydroxyl, amino, cyano, hydroxy(1-6C)alkyl, di[(1-6C)alkyl]amino(1-6C)alkyl, (6-10C)aryl, (3-7C)cycloalkyl, (1-6C)alkyl, (1-6C)alkylcarbonyl, aminosulfonyl, and (1-6C)alkoxy, and
R8 is hydrogen.

US Pat. No. 10,689,342

AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY

1. A compound of formula (I)
or a salt, thereof, wherein:
R1 is:
C1-8 alkyl or heteroalkyl; C2-6 alkenyl or heteroalkenyl; C2-6 alkynyl or heteroalkynyl, all of them optionally substituted;
aryl, alkylaryl, heteroaryl, or alkylheteroaryl, all of them being optionally substituted;
R2, R3, R4 are, each independently:
a hydrogen atom;
C1-8 alkyl or heteroalkyl; C2-6 alkenyl or heteroalkenyl; C2-6 alkynyl or heteroalkynyl, all of them being optionally substituted;
aryl, alkylaryl, heteroaryl, or alkylheteroaryl, all of them being optionally substituted;
or R3 and R4, together with the carbon atoms to which they are bound, form a 5 or 6 membered cycloalkyl, cycloheteroalkyl, aryl or heteroaryl ring being optionally substituted, being optionally fused with one or more other rings;
X is C—R5 or N;
R5 is:
a hydrogen atom;
C1-6 alkyl or heteroalkyl; C2-6 alkenyl or heteroalkenyl; C2-6 alkynyl or heteroalkynyl, all of them being optionally substituted.

US Pat. No. 10,689,341

SMALL MOLECULE N-(ALPHA-PEROXY) INDOLE COMPOUNDS AND METHODS OF USE

KING ABDULLAH UNIVERSITY ...

1. A compound of the following formula:or a pharmaceutically acceptable salt or prodrug thereof, wherein:A1, A2, A3, and A4 are each independently selected from CR and N, wherein each R is selected from the group consisting of hydrogen, halogen, cyano, trifluoromethyl, alkoxy, aryloxy, substituted or unsubstituted carbonyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroalkenyl, substituted or unsubstituted heteroalkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, and substituted or unsubstituted heterocycloalkyl;
R5 and R6 are each independently selected from hydrogen, halogen, cyano, trifluoromethyl, alkoxy, aryloxy, substituted or unsubstituted carbonyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroalkenyl, substituted or unsubstituted heteroalkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, and substituted or unsubstituted heterocycloalkyl; and
R7, R8, and R9 are each independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroalkenyl, substituted or unsubstituted heteroalkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, and substituted or unsubstituted heterocycloalkyl;
wherein R5 and R6 do not combine to form a cyclic compound.

US Pat. No. 10,689,340

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

Janssen Pharmaceuticals, ...

1. A compound selected from the group consisting of:
and stereoisomeric forms, pharmaceutically acceptable salts, solvates or polymorphs thereof.

US Pat. No. 10,689,339

PYRROLIDINE DERIVATIVES

Hoffmann-La Roche Inc., ...

8. A compound which is (2S,4R)-4-[4-(5-Methyl-tetrazol-2-yl)-2-trifluoromethyl-benzenesulfonyl]-1-(1-trifluoromethyl-cyclopropanecarbonyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide or a pharmaceutically acceptable salt or ester thereof.

US Pat. No. 10,689,338

PSYCHOTROPIC AGENTS AND USES THEREOF

LB Pharmaceuticals Inc., ...

1. A compound selected from the group consisting of LB102, LB103, LB104, pharmaceutically acceptable salts of LB102, pharmaceutically acceptable salts of LB103, and pharmaceutically acceptable salts of LB104:

US Pat. No. 10,689,336

RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS

ZEON CORPORATION, Tokyo ...

1. A method for producing a polymer comprising subjecting a radically polymerizable monomer to radical polymerization in a state in which a radical polymerization initiator is present in a polymerization system,wherein the radical polymerization initiator is an organotellurium compound represented by the following formula (1),
wherein R1 represents a group selected from:an alkyl group having 1 to 10 carbon atoms;
a cycloalkyl group having 3 to 10 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
an aryl group having 6 to 20 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms); and
an aromatic heterocyclic group which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 20 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms),
each of R2 and R3 independently represents a group selected from:
a hydrogen atom;
an aliphatic hydrocarbon group having 1 to 10 carbon atoms;
an aryl group having 6 to 20 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
an aromatic heterocyclic group which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms or a haloalkyl group having 1 to 8 carbon atoms);
a halogen atom;
a carboxyl group;
a hydrocarbyl oxycarbonyl group having 2 to 10 carbon atoms;
a cyano group; and
an amide group,
and each of R4, R5 and R6 independently represents a group selected from:
a hydrogen atom;
an aliphatic hydrocarbon group having 1 to 10 carbon atoms;
an aryl group having 6 to 20 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
an aromatic heterocyclic group which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
a halogen atom;
a carboxyl group;
a hydrocarbyl oxycarbonyl group having 2 to 10 carbon atoms;
a cyano group; and
an amide group, and
a group represented by the following formula (2),
wherein 2 groups selected from R2 to R6 may bond together to form a ring other than an aromatic ring,

wherein R7 represents a group selected from:
an alkyl group having 1 to 10 carbon atoms;
a cycloalkyl group having 3 to 10 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
an aryl group having 6 to 20 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms); and
an aromatic heterocyclic group which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 20 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms),
and each of R8 and R9 independently represents a group selected from:
a hydrogen atom;
an aliphatic hydrocarbon group having 1 to 10 carbon atoms;
an aryl group having 6 to 20 carbon atoms which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
an aromatic heterocyclic group which is unsubstituted, or substituted with a substituent selected from a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an amino group, a nitro group, a cyano group, and —CORa (wherein Ra represents an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, or a haloalkyl group having 1 to 8 carbon atoms);
a halogen atom;
a carboxyl group;
a hydrocarbyl oxycarbonyl group having 2 to 10 carbon atoms;
a cyano group; and
an amide group,
wherein the wavy line represents a bond with the carbon atoms constituting the double bond in formula (1),
wherein one of the terminal of the polymer produced is a group represented by (R5)(R6)C?C(R4)—C(R2)(R3)— that is derived from the organotellurium compound.

US Pat. No. 10,689,335

HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF

Georgia State University ...

1. A compound according to Formula I:
or a pharmaceutically acceptable salt thereof, wherein:
subscripts a and b are each 1;
each subscript c is 0;
L1 and L2 are each a bond;
R1 and R2 are taken together to form C6-C10 aryl, which is optionally substituted with 1-3 R4;
each R4 is independently selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, C1-C6 haloalkyl, C1-C6 haloalkoxy, C1-C6 aminoalkyl, C1-C6 aminoalkoxy, C3-C6 cycloalkyl;
R3 is O;
W is O;
Y is a bond and R10 is H, or
Y is —S— and R10 is selected from the group consisting of C1-C6 alkyl and (C6-C10 aryl)-(C1-C6 alkyl), wherein C1-C6 alkyl and (C6-C10 aryl)-(C1-C6 alkyl) are optionally substituted with 1-5 R10a, or wherein C1-C6 alkyl and (C6-C10 aryl)-(C1-C6 alkyl) optionally substituted with —OR? wherein R? is C1-6 alkyl;
Z is selected from the group consisting of —C(?O)R6, —C(?O)OR6, —(CH2)xOR6, —(CH2)x(C(?O)OR6, —(CH2)xOC(?O)R6, —(CH2)xOP(?O)(OR6)x, —OP(?O)(OR6)x, —P(?O)(OR6)x, and R7, wherein each subscript x is independently 0, 1, 2, 3, or 4;
each R8 is independently selected from the group consisting of H and C1-C6 alkyl,
each R9 is independently C1-C6 alkyl,
wherein one R8 is optionally taken together with one R9 to form a double bond;
each R10a is independently selected from the group consisting of C1-C6 alkyl, —C(?O)OR5, —NR5C(?O)OR5, and a moiety —W—Z;
each R5 is independently selected from the group consisting of H and C1-C4 alkyl;
each R6 is independently selected from the group consisting of C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkynyl, and C3-C4 cycloalkyl; and
R7 is a monosaccharide or a non-steroidal anti-inflammatory drug, wherein the non-steroidal anti-inflammatory drug is selected from the group consisting of ibuprofen, naproxen, sulindac, aceclofenac, salicylates, indomethacin, flurbiprofen, diclofenac, ketorolac, etodolac, fenoprofen, flufenamic acid, ketoprofen, mefenamic acid, diflunisal, tolmetin, ketorolac, aspirin, and lumiracoxib.

US Pat. No. 10,689,333

2-MERCAPTOETHANOL SYNTHESIS

Chevron Phillips Chemical...

30. A process comprising:reacting, in a plug flow reactor having a fixed bed containing a solid catalyst comprising LZY-64 catalyst, hydrogen sulfide and an oxirane compound in the presence of the solid catalyst to yield a reaction product comprising a mercapto-alcohol, wherein the mercapto-alcohol comprises 2-mercapto-1-ethanol or 1-mercapto-2-propanol, wherein during steady state operation of the plug flow reactor, the hydrogen sulfide and the oxirane are present in a mole ratio in a range of about 5:1 to about 50:1, wherein an effluent of the plus flow reactor comprises the reaction product, wherein after a single pass through the plug flow reactor a conversion of the oxirane to 2-mercapto-1-ethanol or 1-mercapto-2-propanol is greater than 99 wt. %, and wherein the conversion of the oxirane compound to 2-mercapto-1-ethanol or 1-mercapto-2-propanol is based on a weight of the oxirane compound that converts to 2-mercapto-1-ethanol or 1-mercapto-2-propanol divided by a weight of the oxirane compound fed to the plug flow reactor.

US Pat. No. 10,689,332

RACEMIC BETA-AMINOSULFONE COMPOUNDS

Quimica Sintetica, S.A., ...

1. A process for preparing racemic beta-aminosulfone of formula (I),
the process comprising:
a) reacting 3-ethoxy-4-methoxybenzaldehyde of formula (9) with a compound of formula R1—NH2 and a compound of formula R2—S(O)OH or a salt thereof to obtain an aminosulfone of formula (2):

wherein:
R1 is an amino protecting group; and
R2 is a C1-C6 alkyl, a substituted C1-C6 alkyl, a C6-C10 aryl or a substituted C6-C10 aryl;
b) converting the aminosulfone of formula (2) into a sulfone of formula (3) by treatment with a carbanion derived from dimethyl sulfone:

and
c) deprotecting the sulfone of formula (3) to obtain 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine of formula (1) in the form of a racemic mixture.

US Pat. No. 10,689,331

IDO INHIBITORS

Bristol-Myers Squibb Comp...

1. A compound of Formula (I)wherein:W is CRX,
V is CRX,
Y is CRX;
Z is —O—;
Rx is hydrogen;
R1 is hydrogen, optionally substituted C1-C6 alkyl or C1-C4 alkoxy;
R2 is hydrogen or methyl, or
R1 and R2 are taken together with the carbon to which they are attached to form a 3-6 membered cycloakyl ring;
R4 is —COZR3; wherein when Z is —O—, R3 is H or C1-C4 alkyl;
R5 is hydrogen;
R6 is —COR10 or CONR5R9;
R7 and R8 are independently optionally substituted C1-C6 alkyl, optionally substituted aryl, optionally substituted C1-C6 alkoxy, optionally substituted C3-C8cycloalkyl, optionally substituted C2-C10 alkynyl, optionally substituted 5- to 7-membered monocyclic heterocyclyl, optionally substituted 8- to 10-membered bicyclic heterocyclyl, optionally substituted aryl C1-C6 alkyl, or optionally substituted C2-C6 alkenyl; R9 is optionally substituted C1-C6 alkyl, optionally substituted C3-C8 cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocyclyl; wherein the optional substituents are 1-4 Ry;
Ry is hydrogen, halogen, CN, CF3, C1-C6 alkyl, C1-C6 alkoxy or aryloxy;
R10 is optionally substituted aryl; wherein the optional substituents are 1-4 Rz;
Rz is hydrogen, halogen, CN, CF3, C1-C6 alkyl, C1-C6 alkoxy or aryloxy;
R11 is optionally substituted C1-C6 alkyl, optionally substituted C3-C8 cycloalkyl, trifluoromethyl, phenyl or optionally substituted heterocyclyl;
R12 is hydrogen or optionally substituted C1-C6 alkyl;
R13 is hydrogen or optionally substituted C1-C6 alkyl;and/or a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,689,330

AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM

Bezwada Biomedical, LLC, ...

1. An absorbable compound of formula F:
wherein:
each X is independently selected from:
—OCH2C(O)—;
—OCH(CH3)C(O)—;
—OCH2CH2OCH2C(O)—;
—OCH2CH2CH2CH2CH2C(O)—;
—O(CH2)yC(O)—; and,
—O(CH2CH2O)mCH2C(O)—;
each Y is independently selected from:
—C(O)CH2O—;
—C(O)CH(CH3)O;
—C(O)CH2OCH2CH2O—;
—C(O)CH2CH2CH2CH2CH2O;
—C(O)(CH2)yO—; and,
—C(O)(CH2CH2O)mCH2O—;
m is integer between 2-24 inclusive;
p is independently selected from 1 and 2;
y is one of the numbers 2, 3, 4, and 6-24;
wherein the OCN—R—C(O)O and OC(O)—R—NCO moieties of Formula F (O being from an X or Y group) are an amino acid selected from: alanine, asparagine, aspartic acid, gamma amino butyric acid, glycine, glutamic acid, valine, lysine, isoleucine, leucine, and ornithine; and,
R? is selected from alkyl, aryl and arylalkyl, wherein the alkyl moiety, when present, comprises a primary chain of 2-24 carbon atoms;
optionally, in R?, one or more CH2 groups in the primary chain are replaced with O or S; and,
optionally, in R?, the primary chain or aryl is independently substituted with lower alkyl group(s).

US Pat. No. 10,689,329

TERT-AMINE CORE-BEARING ACYRLAMIDES AND ADHESIVE FORMULATIONS

1. A compound of Formula (II):
wherein:
R1, R2, and R4 are each independently C1-C4 alkyl; and
n1, n2, and n3 are each independently integers selected from the group of 2, 3, and 4.

US Pat. No. 10,689,327

PRODRUG AMINO ACID DERIVATIVE

TAISHO PHARMACEUTICAL CO....

1. A method of treating a condition in a patient in need thereof, comprising administering to said patient a therapeutically effective amount of a compound represented by formula (I-A):
or a pharmaceutically acceptable salt thereof,
wherein
R1 represents a C1-6 alkyl group, a heteroaryl group optionally substituted by one halogen atom, or the following formula (IIIA):

where Rx represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group, wherein the C1-6 alkyl group and the C1-6 alkoxy group are each optionally substituted by one to three halogen atoms, and
Ry represents a hydrogen atom, a fluorine atom, a C1-6 alkyl group, or a C1-6 alkoxy group, wherein the C1-6 alkyl group and the C1-6 alkoxy group are each optionally substituted by one to three halogen atoms,
R1? represents a hydrogen atom or a C1-6 alkyl group,
or R1 and R1? optionally form a C3-8 cycloalkane together with the carbon atom adjacent thereto,
R2 represents a C3-6 alkyl group, a C3-8 cycloalkyl group optionally substituted by one to three C1-6 alkyl groups, a C3-8 cycloalkoxy group optionally substituted by one to three C1-6 alkyl groups and optionally having a C1-5 alkylene group crosslinking two different carbon atoms in the ring, an adamantyl group optionally substituted by one to three C1-6 alkyl groups, or a phenyl group,
R3 represents a hydrogen atom or a C1-6 alkyl group, and
R4 represents a hydrogen atom or a fluorine atom, and
wherein the condition is selected from the group consisting of mood disorders, anxiety disorder, cognitive disorders, developmental disorders, Alzheimer's disease, Parkinson's disease, sleep disorders, Huntington's chorea, eating disorders, drug dependence, epilepsy, brain infarction, cerebral ischemia, cerebral edema, head trauma, inflammation and immune-related diseases.

US Pat. No. 10,689,326

QUATERNIZED AMMONIUM SALTS OF HYDROCARBYL EPOXIDES AND USE THEREOF AS ADDITIVES IN FUELS AND LUBRICANTS

BASF SE, Ludwigshafen (D...

1. A reaction product comprising a quaternized nitrogen compound, obtained by a process comprising:reacting i) at least one hydrocarbyl epoxide, which is a polyalkylene epoxide that is obtained by epoxidizing a polyalkylene, having a number-average molecular weight (Ma) of 85 to 20,000;
with ii) at least one tertiary amine of formula II:
RaRbRcN  (II)
wherein Ra, Rb and Rc are each independently a straight-chain or branched, saturated or unsaturated, optionally substituted hydrocarbyl radical, or two of Ra, Rb and Rc together with the nitrogen atom to which they are bonded, form an optionally substituted 5- to 7-membered, saturated or unsaturated, nonaromatic or aromatic heterocyclic ring which may optionally bear at least one further ring heteroatom selected from 0, S or N;
in the presence of iii) at least one acid of formula III:
H+A?  (III)
in which A? is the anion of at least one of an inorganic acid and an organic acid, wherein the organic acid is selected from the group consisting of C1-C4 monocarboxylic acids, aromatic carboxylic acids, caproic acid, enanthic acid, caprylic acid, pelargonic acid, capric acid, undecanoic acid, lauric acid, tridecanoic acid, myristic acid, pentadecanoic acid, palmitic acid, margaric acid, stearic acid, nonadecanoic acid, arachic acid, behenic acid, lignoceric acid, cerotic acid, melissic acid, monounsaturated fatty acids, diunsaturated fatty acids, triunsaturated fatty acids, tetra- and polyunsaturated fatty acids, ricinoleic acid, gondoic acid, nervonic acid, vernolic acid, malvalic acid, chaulmoogric acid and tall oil fatty acids.

US Pat. No. 10,689,325

PROCESS FOR THE PREPARATION OF AN ANTIBODY-RIFAMYCIN CONJUGATE

Genentech, Inc., South S...

1. A process for the preparation of benzoxazinorifamycin analog IV,
comprising reacting F-benzoxazinorifamycin I,

and a secondary amine R2NH selected from dimethylamine, diethylamine, di-n-propylamine, 1-methylpiperazine, N1-isobutylpiperazine, and N,N-dimethylpiperidin-4-amine, to form IV, where R is selected from methyl, ethyl, and n-propyl, and where two R groups form 1-methylpiperazine, N1-isobutylpiperazine, and N,N-dimethylpiperidin-4-amine;
wherein F-benzoxazinorifamycin I is prepared by a process comprising:
(i) reacting rifamycin S II, and 2-amino-5-fluorobenzene-1,3-diol III in a batch reactor vessel to form I

wherein RIFA SV is formed as a by-product and delivered to a flow-reactor

(ii) one or more oxidants oxidizes the RIFA SV to form II in the flow-reactor, wherein the one or more oxidants are selected from 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO), oxygen gas comprising about 5% to about 100% of the reaction gas phase, and benzoquinone, and
(iii) the II formed in the flow-reactor is delivered to the batch reactor vessel,
wherein the one or more oxidants and 2-amino-5-fluorobenzene-1,3-diol III are kept separate.

US Pat. No. 10,689,324

METABOLISM RESISTANT FENFLURAMINE ANALOGS AND METHODS OF USING THE SAME

ZOGENIX INTERNATIONAL LIM...

1. A method of treating epilepsy comprising:administering to a patient in need thereof a therapeutically effective amount of a metabolism-resistant fenfluramine analog having a structure selected from the group consisting of:

US Pat. No. 10,689,323

PROCESS FOR PREPARATION OF DI- AND POLYAMINES OF THE DIPHENYLMETHANE SERIES

1. A process for preparing diamines and polyamines of the diphenylmethane series (MDA) by reaction of aniline (1) and formaldehyde (2) as a molar ratio of aniline (1) to formaldehyde (2) in normal operation of A/Fnormal operation, which comprises the steps:I) reacting aniline (1) and acid (3) in a reactor to form a reaction mixture containing the anilinium salt of the acid (3) used; and
II) reacting at least part of the reaction mixture obtained in step I) with formaldehyde (2) in a reactor, optionally with introduction of further aniline (1), optionally with the introduction of further acid (3), forming diamines and polyamines of the diphenylmethane series;wherein the following steps are carried out to end the production of the diamines and polyamines of the diphenylmethane series:II.1) reducing the mass flow rate m2 of formaldehyde (2) into the reactor of step II) commencing at a point in time t0, until m2 is zero at a point in time t1, where t1>t0;
I.1) reducing the mass flow rate m1 of aniline into the reactor of step I) and optionally into the reactor of step II), until m1 is zero at a point in time t2, where t2?t1; and
I.2) reducing the mass flow rate m3 of the acid (3) into the reactor of step I) and optionally into the reactor of step II), until m3 is zero;
andthe reduction of the mass flow rates m1 and m2 occurs in such a way that, up to attainment of the point in time t1, the instantaneous molar ratio ofaniline (1) introduced into the reactor of step I) and, if present, aniline (1) introduced into the reactor of step II)toformaldehyde (2) introduced into the reactor of step II),A/Finst., is always ?1.5 and is always ?1.05·A/Fnormal operation.

US Pat. No. 10,689,322

PROCESS FOR PREPARATION OF DI- AND POLYAMINES OF THE DIPHENYLMETHANE SERIES

Covestro Deutschland AG, ...

1. A plant for preparing diamines and polyamines of the diphenylmethane series, which comprises the plant parts:IA) a reactor having an integrated phase separation facility or a reactor and a separate phase separation apparatus configured to react aniline and formaldehyde in the absence of an acid catalyst to form an aminal and configured to subsequently separate the reaction mixture obtained into an aqueous phase and an organic phase containing the aminal; and
IIA) a reactor configured to react the organic phase containing the aminal obtained in the reactor IA) with acid;
or
IB) a reactor configured to react aniline with acid; and
IIB) a reactor configured to react the reaction mixture obtained in the reactor IB) with formaldehyde;
and
III) a reactor configured to neutralize the reaction mixture from IIA) or IIB);
IV) a separation vessel configured to separate the neutralized reaction mixture from III) into an organic phase comprising diamines and polyamines of the diphenylmethane series and an aqueous phase;
V) a washing vessel configured to wash the organic phase from IV) by means of washing liquid;
VI) a separation vessel configured to separate the mixture from V) into an organic phase comprising diamines and polyamines of the diphenylmethane series and an aqueous phase;
VII) a distillation apparatus configured to distill the organic phase from VI) to give diamines and polyamines of the diphenylmethane series and a stream containing water and aniline; and optionally
VIII) a wastewater work-up facility configured to work-up the aqueous phase from IA) and/or the aqueous phase from IV) and/or the aqueous phase from VI) and/or the stream containing water and aniline from VII);
wherein
the plant is configured such that during a shutdown of one or more, but not all, plant parts, the shutdown involving a complete stoppage of the plant part:
introduction of formaldehyde into the reactor IA) or IIB) is interrupted before or at the same time as the shutdown; and
an output stream from at least one of the plant parts which is not shut down is recirculated and the output stream is used as a feed stream for the respective plant part or an upstream plant part.

US Pat. No. 10,689,321

METHOD FOR SYNTHESIZING PARAPHTHALOYL CHLORIDE THROUGH CONTINUOUS FLOW IN MICROCHANNEL REACTOR

Jiangsu Yangnong Chemical...

1. A method for preparing paraphthaloyl chloride through terephthalic acid chlorination in a microchannel reactor, wherein the method comprises the following steps:(1); a preparation of raw materials:
a. firstly melting a paraphthaloyl chloride, and then putting a terephthalic acid and a catalyst into the paraphthaloyl chloride, stirring and mixing, and conducting heat-preserving in a 90 DEG C oil bath to obtain a TPA slurry; and
b. putting a solid triphosgene, conducting stirring, melting and heat-preserving in a 85 DEG C oil bath to obtain a triphosgene liquid;
(2) reaction process:
in a reaction process, using a continuous flow microchannel reactor, guiding the TPA slurry through a heat-preserving insulative slurry pump and a phosgene through a mass flow meter (the triphosgene liquid is fed using a heat-preserving plunger pump), and the two materials enter the reactor in proportion and preform a mixing reaction, to obtain a TPC crude product, absorbing a tail gas by connecting water and alkali.

US Pat. No. 10,689,320

METHOD FOR SEPARATING FORMIC ACID FROM A REACTION MIXTURE BY MEANS OF EXTRACTION

OXFA GMBH, Schesslitz (D...

1. A method for isolating formic acid from a reaction mixture by extraction, wherein the reaction mixture besides the formic acid comprises a polyoxometalate ion of the general formula [PMoxVyO40]n? as catalyst and a solvent which dissolves the catalyst, where 6?x?11, 1?y?6, x+y=12, and 3

US Pat. No. 10,689,319

PROCESSES FOR PURIFYING ACETIC ACID AND HYDRATING ANHYDRIDE

CELANESE INTERNATIONAL CO...

1. A process for producing acetic acid comprising:a. carbonylating, in a reactor, at least one member selected from the group consisting of methanol, dimethyl ether, and methyl acetate in a reaction medium comprising water at a concentration from 0.1 to 14 wt. %, a rhodium catalyst, methyl iodide, and an iodide salt;
b. separating the reaction medium to form a liquid recycle stream and a vapor product stream;
c. distilling at least a portion of the vapor product stream in a first column to obtain an overhead and a sidestream and withdrawing the side stream from a location of the first column having more than 0.2 wt. % water;
i. biphasically separating the overhead to form a light phase comprising water and a heavy phase comprising methyl iodide and at least one PRC; and
ii. treating the heavy phase to remove the at least one PRC;
d. distilling the side stream in a second column to obtain a product stream and withdrawing the product stream from a location of the second column having less than 0.2 wt. % water; and
e. contacting the product stream with a cation exchange resin to form a purified acetic acid product.

US Pat. No. 10,689,317

METHODS OF MAKING FUSED RING COMPOUNDS

Transitions Optical, Inc....

1. An unsaturated compound represented by Formula IIb,
wherein,
m is selected from 1 to 4,
R1 for each m is independently selected from C3-C7 cycloalkyl, C1-C8 haloalkyl, and —O—R10?,
wherein R10? is hydrogen, C1-C20 alkyl, phenyl(C1-C20)alkyl, mono(C1-C20)alkyl substituted phenyl(C1-C20)alkyl, mono(C1-C20)alkoxy substituted phenyl(C1-C20)alkyl, (C1-C20)alkoxy(C2-C20)alkyl, C3-C10 cycloalkyl, or mono(C1-C20)alkyl substituted C3-C10 cycloalkyl;
R3 is selected from C1-C8 alkyl, C1-C8 haloalkyl, and C3-C7 cycloalkyl, and
R16 is selected from C1-C8 alkyl.

US Pat. No. 10,689,314

METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS

Univation Technologies, L...

1. A method for preparing a bridged bi-aromatic phenol ligand of formula (I) from a compound containing at least one phenol group wherein the at least one phenol group remains unprotected during all steps of the method and the method comprises at least one step of aryl coupling;
wherein each of R1, R2, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13 and R14 is independently selected from the group consisting of hydrogen, halide, optionally substituted hydrocarbyl, heteroatom-containing optionally substituted hydrocarbyl, alkoxy, aryloxy, silyl, boryl, dialkyl amino, alkylthio, arylthio and seleno; optionally two or more R groups combine together into ring structures with such ring structures having from 3 to 100 non-hydrogen atoms in the ring; A is a bridging group having from one to 50 non-hydrogen atoms; Y and Y? are independently selected from O, S, NRa and PRa wherein Ra is optionally substituted hydrocarbyl; Ar is optionally substituted aryl or optionally substituted heteroaryl.

US Pat. No. 10,689,313

PROCESSES AND SYSTEMS FOR PURIFICATION OF 1,3-BUTADIENE

SABIC Global Technologies...

1. A system for purifying 1,3-butadiene, comprising:a first distillation column and a second distillation column, each column having a top portion, a bottom portion, and a middle portion;
a first interconnection between the top portion of the first distillation column and the top portion of the second distillation column, wherein the first interconnection is configured to feed a liquid stream from the second distillation column to the first distillation column;
a second interconnection between the bottom portion of the first distillation column and the bottom portion of the second distillation column, wherein the second interconnection is configured to feed a firstgas stream from the second distillation column to the first distillation column;
a top stream line configured to remove a second gas stream from the top portion of the second distillation column, wherein the top stream line is coupled to a heat exchanger;
a vapor outlet line operatively connected to the heat exchanger to recover high volatility componentsfrom the second gas stream;
a feed line forcrude 1,3-butadiene to the first distillation column;
a product outlet line for purified 1,3-butadiene from the second distillation column;
a third interconnection between the top of the first distillation column and the top of the second column to feed a gas stream from the first column to the second column; and
a fourth interconnection between the bottom of the first column to the bottom of the second column to feed liquid from the bottom of the first column to the bottom of the second column;
wherein the second distillation column comprises about 87 theoretical plates; and
wherein the first distillation column has 30 theoretical plates.

US Pat. No. 10,689,312

PROCESS IMPROVEMENTS IN SELECTIVE ETHYLENE OLIGOMERIZATIONS

Chevron Phillip Chemical ...

1. A reaction system comprising:a reaction zone configured to form an oligomer product, the reaction zone comprising ethylene, an organic reaction medium, a catalyst system, the oligomer product, and optionally hydrogen;
a first reaction zone inlet connected to the reaction zone and configured to introduce the catalyst system comprising i) a chromium component comprising an N2-phosphinyl amidine chromium compound complex, an N2-phosphinyl formamidine chromium compound complex, an N2-phosphinyl guanidine chromium compound complex, or any combination thereof, and ii) an aluminoxane to the reaction zone;
a second reaction zone inlet connected to the reaction zone and configured to introduce an ethylene feedstock mixture comprising ethylene, at least a portion of the organic reaction medium, and optionally hydrogen to the reaction zone;
one or more reaction zone outlets connected to the reaction zone and configured to discharge a reaction zone effluent comprising at least a portion of the oligomer product from the reaction zone;
an ethylene feed line comprising ethylene; and
an organic reaction medium feed line comprising the organic reaction medium, wherein the ethylene feed line and the organic reaction medium feed line are configured to combine to form an ethylene feedstock mixture line, wherein the ethylene feedstock mixture line is connected to or coupled to the second reaction zone inlet;
wherein the catalyst system is fed into the reaction zone separately of the ethylene feedstock mixture.

US Pat. No. 10,689,310

METHOD FOR PRODUCING ALPHA-OLEFIN LOW POLYMER

1. A method for producing an ?-olefin oligomer, the method comprising:oligomerizing an ?-olefin in the presence of i) a catalyst comprising a transition metal-containing compound (a), a nitrogen-containing compound (b), an alkylaluminum compound (c) and chlorine-containing compounds (d), and ii) a reaction solvent to produce the ?-olefin oligomer,
wherein:
the chlorine-containing compounds (d) comprise at least one first chlorine-containing compound (d)-1 selected from the group consisting of diethylaluminum chloride and hexachloroethane, and a second chlorine-containing compound (d)-2 which is 1,1,2,2-tetrachloroethane;
the chlorine containing compounds (d) is supplied at an amount, relative to the transition metal-containing compound (a), in the range of 2 molar equivalents to 50 molar equivalents in the oligomerizing;
the ratio of the second chlorine containing compound (d)-2 to the total amount of the chlorine-containing compounds (d) is 1 mol % or more and 49 mol % or less;
the second chlorine-containing compound (d)-2 has the lowest chlorine atom elimination rate among the chlorine-containing compounds (d); and
the chlorine atom elimination rate is determined by reacting the chlorine-containing compounds (d)-1 and (d)-2 with the alkylaluminum compound (c) under stirring at 80° C. for a reaction period of 2 hours and dividing the difference between the remaining amount of (d)-1 and (d)-2 and the initial amount of (d)-1 and (d)-2, respectively.

US Pat. No. 10,689,309

FUSED-RING ALKANE FUEL AND PHOTOCATALYTIC PREPARATION PROCESS THEREOF

TIANJIN UNIVERSITY, Tian...

1. A process for preparing a fused-ring alkane fuel, wherein the fused-ring alkane fuel has the following structure:
wherein n is 1 or 2; R1, R2, R3, R4 and R5 are H or —CH3 or —CH2CH3;
the fused-ring alkane fuel has a density of greater than 0.870 g/cm3, a freezing point of not higher than ?50° C., and a net mass heat value of not less than 42.0 MJ/kg; and
the process for preparing a fused-ring alkane fuel, wherein the process comprises steps of:
(1) in a presence of ultraviolet light and a photocatalyst, a Diels-Alder cycloaddition reaction between a substituted or unsubstituted cyclic enone and a substituted or unsubstituted furan molecule occurs to produce a fuel precursor molecule:

(2) the fuel precursor molecule obtained in the step (1) is subjected to hydrodeoxygenation to produce the fused-ring alkane fuel.

US Pat. No. 10,689,307

COMPOSTING METHOD

Wilfred Hoath, Fort Nels...

1. A composting method comprising:layering a base bedding material on a ground surface;
layering a bottom organic waste material layer on said base bedding material layer;
layering a stack of one or more intermediate bedding material layers and one or more intermediate organic waste material layers, alternating between an intermediate bedding material layer and an intermediate organic waste material layer, on said bottom organic waste material layer to partially form a compost heap;
layering a top bedding material layer on a top organic waste material layer of said stack of said intermediate bedding material layers and said intermediate organic waste material layers to form said compost heap;
watering said compost heap at a watering cycle;
introducing worms to said compost heap; aerating said compost heap at an aeration cycle; and,
harvesting compost from said compost heap, said compost comprising decomposed organic waste material, decomposed bedding material and vermicast.

US Pat. No. 10,689,306

FERTILIZER COMPOSITION AND METHODS OF MAKING AND USING SAME

SABIC GLOBAL TECHNOLOGIES...

1. A fertilizer granule comprising a core particle having an outer surface coated with a first nitrogen containing fertilizer composition, the core particle comprising:one or more fertilizer additives comprising a urease inhibitor or a nitrification inhibitor, or a combination thereof;
one or more binders comprising a wax; and
one or more pH buffering agents, andwherein the core particle comprises from about 10 wt % to about 99 wt % of the one or more binders comprising a wax.

US Pat. No. 10,689,305

SYSTEMS AND METHODS FOR PRODUCING A CARBON COMPOSITE MATERIAL

GOODRICH CORPORATION, Ch...

1. A method of manufacturing a carbon/carbon brake disk comprising:forming a fibrous network from an oxidized carbon fiber precursor; subsequently
carbonizing the oxidized carbon fiber precursor in a furnace by heating the oxidized carbon fiber precursor at a first temperature in a first range of about 1,400° C. to 2,800° C. to form a carbon fiber preform; subsequently
infiltrating the carbon fiber preform with carbon using chemical vapor infiltration or deposition (CVI/CVD) processing, by flowing at least one hydrocarbon gas into the furnace and by decreasing the first temperature in the furnace to a second temperature in a second range of about 900° C. to 1,100° C., to increase a density of the carbon fiber preform to form a carbon/carbon (C/C) part having a first portion with a first coefficient of friction; subsequently
stopping the flow of the at least one hydrocarbon gas into the furnace; subsequently
heat treating the C/C part, by increasing the second temperature in the furnace to a third temperature in a third range of about 1,200° C. to 2,600° C. to form a microscopic crack in the C/C part; and subsequently
performing a final chemical vapor deposition (CVD) process after the heat treating the C/C part, by reducing the third temperature in the furnace to the second temperature in the second range of about 900° C. to 1,100° C. to at least partially fill in the microscopic crack in the C/C part with carbon having a second coefficient of friction different from the first coefficient of friction,
wherein the C/C part includes the first portion comprising the first coefficient of friction and a second portion comprising the second coefficient of friction within the microscopic crack, and
wherein the first portion comprises a first carbon that is heated between 900 to 1,100° C. and 1,200 to 2,600° C. and the second portion comprises a second carbon heated between 900 to 1,100° C. only.

US Pat. No. 10,689,303

ADDITIVE CONTAINING A SUPERPLASTICIZER AND A COPOLYMER

SIKA TECHNOLOGY AG, Baar...

1. An admixture comprising:a) a superplasticizer and
b) a copolymer having a polymer backbone and side chains bonded thereto, the copolymer comprising:
at least one ionizable monomer unit M1 and
at least one side chain-bearing monomer unit M2,
wherein:
the copolymer has a nonrandom distribution of the monomer units M1 and/or the monomer units M2 in a direction along the polymer backbone,
the superplasticizer and the copolymer differ from a chemical and/or structural point of view, and
the superplasticizer comprises the following substructure units:
a) a molar parts of a substructure unit S1 of formula I

b) b molar parts of a substructure unit S2 of formula II

c) c molar parts of a substructure unit S3 of formula (III)

d) d molar parts of a substructure unit S4 of formula (IV)

where:
L independently represents H+, an alkali metal ion, an alkaline earth metal ion, a di- or trivalent metal ion, an ammonium ion or an organic ammonium group,
each Ru independently of any other is hydrogen or a methyl group,
each Rv independently of any other is hydrogen or —COOM,
r=0, 1, or 2,
t=0 or 1,
G1 and G2 are each independently a C1- to C20-alkyl group, -cycloalkyl group, -alkylaryl group, or -[A?O]s-G4, where A?=C2- to C4-alkylene, G4 is H, a C1- to C20-alkyl group, -cycloalkyl group, or -alkylaryl group, and s=2-250,
G3 is independently —NH2, —NG5G6, or —OG7NG8G9,
where:
G5 and G6 are each independently
a C1- to C20-alkyl group, -cycloalkyl group, -alkylaryl group, or -aryl group, or
are a hydroxyalkyl group, an acetoxyethyl group (CH3—CO—O—CH2—CH2—), a hydroxyisopropyl group (HO—CH(CH3)—CH2), or an acetoxyisopropyl group (CH3—CO—O—CH(CH3)—CH2—); or
G5 and G6 together form a ring, which includes the nitrogen, in order to form a morpholine or imidazoline ring;
G7 is a C2-C4-alkylene group,
G8 and G9 each independently represents a C1- to C20-alkyl group, -cycloalkyl group, -alkylaryl group, -aryl group, or a hydroxyalkyl group, and
a, b, c and d represent molar proportions of the respective substructure units S1, S2, S3 and S4,
a/b/c/d=(0.1-0.9)/(0.1-0.9)/(0-0.8)/(0-0.8), and
with the proviso that a+b+c+d=1.

US Pat. No. 10,689,302

SYSTEM, METHOD AND APPARATUS FOR ENTRAINING AIR IN CONCRETE

MACH IV, LLC, Dallas, TX...

1. A system for making a foam comprising:a set of mixers;
a water supply circuit switchably connected to the set of mixers;
an air entrainment solution supply circuit switchably connected to the set of mixers; the air entrainment solution supply circuit configured to recirculate a solution in a batch tank; the air entrainment solution supply circuit switchably separate from a mixing operation; and,
an air supply switchably connected to the set of mixers.

US Pat. No. 10,689,301

METHOD OF MAKING A POROUS FUEL CELL COMPONENT

DOOSAN FUEL CELL AMERICA,...

1. A method of making a porous carbon composite, the method comprising:mixing a carbon-based material, a binder and pore former particles to establish a mixture;
placing the mixture into a mold;
subjecting the mixture in the mold to pressure above 3,000 psi at an ambient temperature to form a compacted body; and
subsequently heating the compacted body to a temperature that causes at least partial removal of the pore former particles to establish pores in place of at least some of the pore former particles.

US Pat. No. 10,689,300

CERAMIC BONDED BODY

KYOCERA CORPORATION, Kyo...

1. A ceramic bonded body, comprising:a first silicon carbide ceramics;
a second silicon carbide ceramics; and
a bonding layer located between the first silicon carbide ceramics and the second silicon carbide ceramics,
the bonding layer containing, with respect to 100 mass % of all components in the bonding layer,
25 mass % or more of metallic silicon, and
25 mass % or more of silicon carbide, wherein a total of the metallic silicon and the silicon carbide is 75 mass % or more,
the bonding layer further containing at least one of nickel silicide and chromium silicide, and
wherein a porosity in the bonding layer is 0.8% or less.

US Pat. No. 10,689,299

METHOD FOR MAKING CERAMIC MATRIX COMPOSITE ARTICLES

Rolls-Royce Corporation, ...

1. A composite article, comprising:20 vol % to 60 vol % of inorganic fibers chosen from aluminum oxide (Al2O3), mullite (Al6Si2O13), zirconium oxide (ZrO2), carbon (C), graphite, silicon carbide (SiC), silicon carbon nitride, silicon nitride, and mixtures and combinations thereof;
1 vol % to 79 vol % of particles chosen from aluminum nitride, aluminum diboride, boron carbide, aluminum oxide, mullite, zirconium oxide, carbon, silicon carbide, silicon nitride, transition metal nitrides, transition metal borides, rare earth oxides, and mixtures and combinations thereof;
1 vol % to 79 vol % of an alloy chosen from Si, B, Al, Y, Ti, Zr, oxides thereof, and mixtures and combinations thereof; and
greater than 0 wt % and less than 1.0 wt % of a polymerized gel.

US Pat. No. 10,689,298

COMPOSITE MATERIAL PART INCLUDING AN INTERPHASE LAYER OF ALUMINUM-DOPED BORON NITRIDE

SAFRAN CERAMICS, Le Hail...

1. A composite material part comprising fiber reinforcement made of carbon or ceramic yarns and a matrix that is mostly ceramic, the part further comprising a first interphase layer covering the yarns and present between the yarns and the matrix, said first interphase layer being a layer of boron nitride doped with aluminum and presenting an atom content of aluminum lying in the range 5% to 15%, in order for said first interphase layer to chemically retain liquid B2O3 oxide by forming crystals of compounds defined as aB2O3.bAl2O3 where a and b are integers in an atmosphere that is wet and at high temperature.

US Pat. No. 10,689,291

GLASS SURFACE PATTERN PRINTING PROCESS

Guangdong Shone Lighting ...

1. A glass pattern printing process comprising:screen printing a first layer of a ground color on a front side of a glass, wherein the ground color is selected according to a pattern and hue, and wherein the ground color is semi-transparent;
screen-printing at least one layer of an additional color on the first layer of the ground color;
screen-printing a layer of a transparent and high-temperature glaze on the first layer containing the at least one layer of the additional color after the at least one layer of the additional color has been screen-printed on the first layer of the ground color;
printing a layer of a frosted glaze including raised specially manufactured marble or wood grains and sunken shallow grains on the layer of the transparent and high-temperature glaze;
applying one or more additional layers of high-temperature glaze and screen-printing in a tempering furnace; and
sintering the glass to form a compact coating.

US Pat. No. 10,689,290

FORMULATIONS FOR OXIDATION PROTECTION OF COMPOSITE ARTICLES

GOODRICH CORPORATION, Ch...

1. A method for limiting an oxidation reaction in a composite substrate, comprising:applying a base layer comprising a first phosphate glass composition on an outer surface of a carbon-carbon composite structure, wherein the first phosphate glass composition comprises a plurality of graphene nanoplatelets and a boron nitride additive; and
heating the carbon-carbon composite structure to a temperature sufficient to adhere the base layer to the carbon-carbon composite structure.

US Pat. No. 10,689,289

OPTICAL GLASS, PREFORM, AND OPTICAL ELEMENT

OHARA INC., Kanagawa (JP...

1. An optical glass comprising, in mass %,more than 34.0% to 70.0% of an SiO2 component,
more than 15.0% and no more than 50.0 of an Nb2O5 component, 1.0 to 30.0% of an Na2O component,
more than 1.0% and no more than 25.0% of a ZrO2 component,
no more than 30.0% of a ZnO component,
less than 5.0% of a K2O component,
less than 1.9% of a CaO component,
less than 5.0% of a BaO component, and
less than 1.0% of an La2O3 component,
less than 0.5% of a Ta2O5 component,
and having
a mass ratio (Li2O+Na2O)/(ZrO2) of no less than 1.30,
a mass ratio (SiO2)/(SiO2+B2O3) of no less than 0.50 and less than 0.98,
a refractive index (nd) of 1.62 to 1.75,
an Abbe number (?d) of 30 to 42, and
a partial dispersion ratio (?g,F) of no greater than 0.594.

US Pat. No. 10,689,287

METHOD FOR EFFICIENTLY PREPARING DOPED OPTICAL FIBRE PREFORM AND DOPED OPTICAL FIBRE PREFORM

FIBERHOME TELECOMMUNICATI...

1. A method for efficiently preparing a doped optical fibre preform, the method comprising the following steps:S1, mixing a rare earth material or a functional metal material with a co-doping agent in a certain proportion, and adding a solvent to formulate a doping solution; mixing and evenly stirring a high-purity quartz powder having a purity of over 99% with the doping solution to obtain a doped precursor; drying the doped precursor at a temperature of 100° C.-150° C. for 12-48 hours, crushing the doped precursor, and screening the crushed precursor through a mesh sieve with over 150 meshes to obtain a doped quartz powder;
S2, disposing a target rod in a plasma outward spraying deposition device, introducing the doped quartz powder, oxygen and/or other gaseous co-doping substances into a plasma heating zone in the plasma outward spraying deposition device, and depositing the doped quartz powder onto the surface of the target rod in a certain proportion to form a doped core layer; stopping introduction of the doped quartz powder, introducing the high-purity quartz powder, oxygen and/or other gaseous co-doping substances, and depositing the high-purity quartz powder onto the surface of the doped core layer in a predetermined proportion to form a quartz outer cladding; and
S3, removing the target rod, and gradually collapsing the entirety formed from the doped core layer and the quartz outer cladding at a high temperature of 900° C.-1800° C. to obtain the doped optical fibre preform.

US Pat. No. 10,689,286

SEPARATION OF GLASS SHAPES USING ENGINEERED INDUCED THERMAL GRADIENTS AFTER PROCESS CUTTING

SEAGATE TECHNOLOGY LLC, ...

1. A method comprising:cutting an outer diameter into a glass substrate;
cutting an inner diameter within the outer diameter into the glass substrate;
applying heat to the glass substrate to generate an engineered temperature gradient that extends through a first region inside the outer diameter and a second region inside the inner diameter, the engineered temperature gradient decreasing in temperature with increasing distance away from the outer diameter and toward the inner diameter; and
applying a cooling source to invert the engineered temperature gradient within the second region inside the inner diameter, wherein the cooling causes the second region to detach from the first region.

US Pat. No. 10,689,285

METHOD FOR LASER-ASSITED SEPARATION OF A PORTION FROM A SHEET-LIKE GLASS OR GLASS CERAMIC ELEMENT

SCHOTT AG, Mainz (DE)

1. A method for separating a portion from a sheet-like glass or glass ceramic element along a separation line that divides the element into the portion and a main part, comprising:producing filamentary damages in a volume of the element adjacently aligned along the separation line to define the portion, the filamentary damages being produced by displacing incidence points of a laser pulses of a laser over a surface of the element along the separation line, the element comprising a material transparent for the laser pulses; and
subjecting the material of the element located in a region of the portion to a phase transition, the phase transition causing contraction of the material in the region so that the portion detaches from the main part along the separation line with at least the main part remaining intact as a whole.

US Pat. No. 10,689,284

INFRARED (IR) TRANSMITTING GRADED INDEX (GRIN) OPTICAL ELEMENTS AND METHOD FOR MAKING SAME

THE GOVERNMENT OF THE UNI...

1. A method of forming an optical stack for an infrared-transmitting graded index optical element, comprising:assembling a plurality of layer pairs into a stack such that each layer pair is in contact with at least one other layer pair, wherein each layer pair includes a first material layer of a first material disposed adjacent to and in contact with a second material layer of second material, different from the first material,
wherein the first material and the second material are infrared-transmitting materials,
wherein a glass transition temperature of the first material is within 5° C. of a glass transition temperature of the second material, and
wherein the first infrared transmitting material is As40 S40 and Se20 and the second infrared transmitting material is As35.5 and S64.5.

US Pat. No. 10,689,282

HYDROTHERMAL LIQUEFACTION CO-PROCESSING OF WASTEWATER SLUDGE AND LIGNOCELLULOSIC BIOMASS FOR CO-PRODUCTION OF BIO-GAS AND BIO-OILS

THE UNIVERSITY OF WESTERN...

1. A process of coproduction of biogas and bio-crude oil, comprising:a) mixing wastewater sludge with waste lignocellulosic biomass to form a mixture with an overall solid content in a range from about 5 to about 25 wt %;
b) subjecting the mixture to hydrothermal liquefaction in a reactor at held at a temperature in a range from about 200 to about 350° C. under pressure in a range from about 50 to about 150 bars and in the presence of a catalyst to give a reaction product;
c) removing and collecting solid bio-char from the reaction product in the reactor, removing and collecting bio-oil from the reaction product in the reactor, and removing and collecting aqueous products from the reaction product in the reactor; and
d) anaerobically digesting the aqueous products to produce and collecting biogas produced from the anaerobically digested aqueous products.

US Pat. No. 10,689,281

MOBILE PROCESSING SYSTEM FOR HAZARDOUS AND RADIOACTIVE ISOTOPE REMOVAL

Kurion, Inc., Irvine, CA...

1. A modular nuclear waste processing method, comprising:providing a modular nuclear waste processing system including two or more process modules;
configuring two or more process modules as standard intermodal shipping containers, and wherein the modular nuclear waste processing system is further configured to:
monitor chemical properties of nuclear process waste water input to a first process module, wherein the monitoring is at least one of manual and automatic, wherein the first process module is configured to mix a metered quantity of a sorbent into the nuclear process waste water, wherein the metered quantity is determined stoichiometrically based on the monitored chemical properties of the nuclear process waste water, and wherein the metered quantity is one of manually and automatically fed into the system;
feed the sorbent treated water from the first process module outlet to a second process module, wherein the second process module comprises one or more vessels containing ion exchange media;
monitor the chemical properties of the sorbent treated water going into the second process module, wherein the monitoring is at least one of manual and automatic;
responsive to the monitored chemical properties of the sorbent treated water going into the second process module, adjust the metered quantity of the sorbent;
monitor the chemical properties of the water at an outlet from the second process module wherein the monitoring is at least one of manual and automatic; and
responsive to the monitored chemical properties of the water at the outlet from the second process module, one of confirm and fine-tune the metered quantity of sorbent.

US Pat. No. 10,689,279

SYSTEM FOR WASTEWATER TREATMENT THROUGH CONTROLLING MICROORGANISM PURIFICATION FUNCTIONS

1. A system for wastewater treatment through controlling microorganism purification functions, comprising:a gas generator configured to provide at least one reactive gas into a return sludge that comprises aerobic microorganisms capable of exhibiting at least one of a reproductive function, by which the microorganisms absorb organic pollutants and multiply using the absorbed pollutants, and a digestive function, by which the microorganisms digest the organic pollutants as a source of energy into water molecules and molecules that comprise carbon, wherein the return sludge is substantially free of the organic pollutants and wherein at least a majority of the microorganisms are in a dormant state before the at least one reactive gas is provided;
a machine comprising one of an atomizer or a cavitation pump and configured to form a gas-dispersion return sludge by rendering the at least one reactive gas into ultra-fine bubbles within the return sludge, wherein a portion of the ultra-fine bubbles dissolves within the return sludge, wherein the at least one dissolved reactive gas activates at least a portion of the dormant microorganisms, and wherein the gas-dispersion return sludge is substantially free of the organic pollutants; and
a controller in control of the machine and configured to:
obtain an amount of the return sludge to be produced by the microorganisms;
determine a ratio of a volume of wastewater comprising at least some of the organic pollutants to a volume of the gas-dispersion return sludge necessary to produce the amount of the return sludge; and
control the machine to form a mixed liquor by combining the gas-dispersion return sludge with the wastewater in accordance with the ratio, wherein the microorganisms prioritize one of the digestive or the reproduction function based on an availability of the organic pollutants in the mixed liquor.

US Pat. No. 10,689,278

SYSTEM AND METHOD FOR CONTROLLED GAS-DISPERSION-RETURN-SLUDGE-BASED WASTEWATER TREATMENT

1. A system for controlled gas-dispersion-return-sludge-based wastewater treatment, comprising:a sedimentation vessel into which wastewater comprising inorganic solids and solid organic materials is pumped and in which at least some of the inorganic solids settles from the wastewater;
an adjustment vessel into which the wastewater from the sedimentation vessel is pumped and which comprises anaerobic organisms that solubilize at least some of the solid organic materials within the wastewater;
one or more aerobic reaction vessels into which the wastewater from the adjustment vessel is pumped and in which the wastewater pumped from the adjustment vessel mixes with a gas-dispersion return sludge to form a mixed liquor, the gas-dispersion return sludge comprising at least one reactive gas a portion of which is dissolved and a portion of which is in a state of ultra-fine bubbles, the gas-dispersion return sludge further comprising aerobic microorganisms that immobilize the solubilized organic materials within the mixed liquor as activated sludge using the at least one dissolved reactive gas, wherein at least some of the ultra-fine bubbles dissolve within the mixed liquor upon a consumption of the dissolved portion of the reactive gases by the aerobic microorganisms;
a sludge sedimentation vessel into which the mixed liquor is pumped from the one or more aerobic reaction vessels and in which the mixed liquor is separated into a supernatant and the activated sludge;
a sludge storage vessel into which the activated sludge from the sludge sedimentation vessel is pumped, wherein at least some of the activated sludge from the sludge storage vessel is pumped to a line atomizer as a return sludge;
a gas generator configured to generate the at least one reactive gas;
the line atomizer configured to form the gas-dispersion return sludge by rendering at least a portion of the at least one reactive gas generated by the gas generator into the ultra-fine bubbles within the return sludge, wherein a portion of the ultra-fine bubbles dissolves within the return sludge, the line atomizer further configured to pump the gas-dispersion return sludge into the aerobic reaction vessel; and
a controller interfaced to the sludge storage vessel, the line atomizer, and the gas generator, the controller configured to receive user input and to control an amount of the gas-dispersion return sludge pumped into the one or more aerobic reaction vessels based on the user input.

US Pat. No. 10,689,277

APPARATUS FOR THE BIO-REMEDIATION OF A WASTE WATER COMPOSITION

IMET CORPORATION, Clevel...

1. An apparatus for the bio-remediation of waste water, comprising:a solid side wall bio-remediation reactor having a plurality of bio-remediation stages therein, said stages separated by a perforated separator, said reactor having a bottom separator;
said reactor having a plurality of porous packing substrates located in said bio-remediation stages and said substrates having one or more microorganisms attached thereto; said packing having micropores therein;
at least one perforated chimney pipe located within said reactor;
said reactor having an open bottom area located below said bottom separator; and said reactor having no air or oxygen, or both, inlet pipe, said stage reactor having one or more supports; and
said reactor capable of being located in a waste water aeration treatment tank containing aerators and waste water therein.

US Pat. No. 10,689,276

SYSTEM AND METHOD FOR WATER DISINFECTION

1. A system for liquid disinfection, comprising:one or more pipes through which a liquid contaminated by microorganisms is supplied to a cavitation pump;
a gas generator configured to generate a gas mixture comprising a plurality of gases and to pump the gas mixture into one or more of the pipes, wherein the gas mixture mixes with the liquid within one or more of the pipes;
a cavitation pump configured to provide cavitation by an impeller of the pump under a pressure of substantially 0.0981 MPa-5.394 MPa and to cause a formation in the liquid of ultra-fine bubbles via the impeller slicing larger bubbles into the ultra-fine bubbles, to dissolve a portion of the gas mixture within the liquid via the cavitation, and to pump the liquid, the ultra-fine bubbles within the liquid, and the remaining undissolved gas mixture into a line atomizer; and
the line atomizer configured to dissolve a further portion of the gas mixture into the liquid by churning and mixing the liquid, the ultra-fine bubbles, and the gas mixture under the pressure of substantially 0.0981 MPa-5.394 MPa, wherein the dissolved gases reduce a concentration of microorganisms within the liquid.

US Pat. No. 10,689,275

ROTATING CONTACTOR REACTOR

DE MONTFORT UNIVERSITY, ...

1. A reactor for the treatment of a liquid stream, the reactor comprising: a liquid stream inlet, a reaction zone for holding the liquid stream, at least one rotating contactor in the reaction in the reaction zone arranged to rotate through the liquid stream, and a liquid outlet, wherein the at least one rotating contactor includes a fabric mesh that includes an ion exchange material.

US Pat. No. 10,689,274

WASTEWATER TREATMENT APPARATUS TO ACHIEVE CLASS B BIOSOLIDS USING CHLORINE DIOXIDE

BCR ENVIRONMENTAL CORPORA...

1. A method for treating a waste stream comprising biosolids so as to achieve a SOUR of 1.5 mg O2/g/hr or less and an ORP of at least +300 mV in the waste stream, the waste stream being provided at varying flow rates and solids concentrations, the method comprising:adjusting a suspended solids content as a percent of the total volume of the waste stream to five (5) weight percent or less;
generating chlorine dioxide in an on-site generator; and
delivering the chlorine dioxide to a conduit comprising a treatment zone through which the waste stream flows so as to achieve a dose rate between 25 and 200 parts per million of the waste stream in the treatment zone and complete dispersal of chlorine dioxide in the waste stream within 30 seconds of delivery to the conduit to provide a treated biosolids sample.

US Pat. No. 10,689,273

CLARIFIER FOR WATER TREATMENT

Xylem Water Solutions Zel...

1. A clarifier for water treatment comprising:a plurality of planar inclined sheets comprising a flexible polymeric material,
wherein each sheet comprises a hydrophobic surface, and
wherein the hydrophobic surface has an average surface roughness (Sa) of from 3 to 100 ?m.

US Pat. No. 10,689,272

CAPACITIVE DEIONISATION

Fujifilm Manufacturing Eu...

1. An electrode unit comprising:(a) an electrically non-conductive circumferential housing;
(b) a current collector;
(c) an electrode;
(d) optionally a charge barrier; and
(e) an electrically conductive connector in electrical contact with the current collector;wherein:(i) the current collector, the electrode, the charge barrier, when the charge barrier is present, and a part of the electrically conductive connector are located within the circumference of the circumferential housing;
(ii) the part of the connector which is located within the housing and the current collector each have a main plane and the main plane of the connector is oriented substantially parallel to the main plane of the current collector;
(iii) the connector extends beyond the housing; and
(iv) the major cross-sectional area of the part of the connector which is inside the housing is less than 30% of the major cross-sectional area of the current collector.

US Pat. No. 10,689,271

SYSTEM AND METHOD FOR OXIDATION OF AMMONIA

XOGEN TECHNOLOGIES INC., ...

1. A method for continuously treating a wastewater that includes ammonia, the method comprising:accepting the wastewater into an electrochemical cell at a variable flow rate;
generating chlorine from chloride present in the wastewater using an anode of the electrochemical cell;
generating a treated effluent by allowing the generated chlorine to form hypochlorous acid, and permitting the hypochlorous acid to oxidize the ammonia;
measuring the concentration of ammonia in the effluent;
measuring the concentration of chlorine in the effluent;
controlling, based on at least one of the measured ammonia and chlorine concentrations:
the current density of the anode of the electrochemical cell; or
the flow rate of the wastewater accepted by the electrochemical cell; or
both the current density of the anode of the electrochemical cell and the flow rate of the wastewater accepted by the electrochemical cell;
wherein controlling the current density of the anode of the electrochemical cell, comprises:
a1) increasing the current density applied to the anode by an amount when the ammonia concentration in the effluent exceeds 0.5 ppm and the current density is less than 12 mA/cm2;
a2) decreasing the current density applied to the anode by an amount when the ammonia concentration in the effluent is less than 0.5 ppm and the concentration of chlorine is from 0.8-2 ppm; or
a3) decreasing the current density applied to the anode by an amount greater than the decrease in current density when the ammonia concentration in the effluent is less than 0.5 ppm and the concentration of chlorine is from 0.8-2 ppm, the greater decrease being when the ammonia concentration in the effluent is less than 0.5 ppm and the concentration of chlorine is from 2-10 ppm;
and wherein controlling the flow rate of the wastewater comprises:
b1) reducing the flow rate of the wastewater accepted into the electrochemical cell when the ammonia concentration in the effluent exceeds 0.5 ppm and the current density is 12 mA/cm2 or greater; or
b2) increasing the flow rate of the wastewater accepted into the electrochemical cell when the flow rate is less than an initial flow rate and when the ammonia concentration in the effluent is less than 0.5 ppm and the concentration of chlorine is from 0.8-2 ppm.

US Pat. No. 10,689,270

CENTRIFUGAL REVERSE OSMOSIS SYSTEM

Centrifugal Solutions LLC...

1. A reverse osmosis system for separating a source liquid into permeate and concentrate, the system comprising:a wheel formed of a hollow central hub, radial tubes fluidly connected to the central hub, semi-permeable membranes provided in each radial tube, a permeate outlet tube fluidly connected to the radial tubes and communicating with the semi-permeable membranes, and a concentrate outlet tube disposed parallel to the central hub, fluidly connected to the radial tubes, and communicating with the semi-permeable membranes;
a permeate collection tank fluidly connected to the permeate outlet tube;
an annular concentrate collection tank disposed about an axial center of the central hub and fluidly connected to the concentrate outlet tube; and
a drive mechanism connected to the central hub of the wheel to rotationally drive the wheel,
wherein the drive mechanism rotationally drives the wheel while the source liquid is supplied to the central hub of the wheel, the rotation causing the source liquid to enter the radial tubes in radially outward directions and generating pressure increase on the source liquid within the radial tubes, the pressure increase generated within the radial tubes being sufficient to force the source liquid through the semi-permeable membranes to separate into the permeate and the concentrate, the permeate being directed to the permeate collection tank through the permeate outlet tube and the concentrate being directed to the concentrate collection tank through the concentrate outlet tube.

US Pat. No. 10,689,269

FLUID TREATMENT SYSTEM

TROJAN TECHNOLOGIES, Lon...

1. A device for fluid treatment, comprisinga radiation source assembly,
and a tubular fluid conduit that is at least partially transparent to radiation from the source assembly,
wherein the tubular fluid conduit is configured to have at least a first curved section and a second curved section sequentially adjacent to the first curved section,
wherein the first curved section and the second curved section are non-parallel sections,
wherein the first curved section and the second curved section alternate sequentially to form a non-helical shape of the tubular fluid conduit;
wherein the first curved section is in a first plane and the second curved section is in a second plane, and the first plane and the second plane are at an angle to one another.

US Pat. No. 10,689,268

COATED POROUS SUBSTRATES FOR OIL AND GAS OR CHEMICAL PROCESSING WASTEWATER TREATMENT

Halliburton Energy Servic...

1. A method comprising:contacting an aqueous waste stream comprising a contaminant with a coated porous substrate, wherein the coated porous substrate is coated with a hydrophilic or oleophobic coating, wherein the hydrophilic or oleophobic coating comprises graphene oxide; and
passing the aqueous waste stream through the coated porous substrate to provide treated water,
whereby the concentration of the contaminant in the treated water is less than the concentration of the contaminant in the aqueous waste stream,
and wherein the aqueous waste stream comprises a waste or catchment stream from (i) a hydrocarbon (HC) exploration, production, transportation, or storage facility, (ii) a chemical production, transportation, or storage facility, or (iii) a combination thereof.

US Pat. No. 10,689,267

METHOD FOR REMOVING ORGANIC DYES FROM WATER USING A HEMOGLOBIN/FE3O4 COMPOSITE ADSORBENT

The United States of Amer...

1. A method to remove organic dyes from water containing said organic dyes, said method comprising contacting said water with an effective organic dyes removing amount of hemoglobin/Fe3O4 composite where said organic dyes in said water adsorb onto said hemoglobin/Fe3O4 composite, and removing said hemoglobin/Fe3O4 composite from said water; wherein at least 95% of the initial concentration of said organic dyes are removed from said water; and wherein said hemoglobin/Fe3O4 composite is prepared by a process comprising adding hemoglobin to an aqueous solution containing Fe3+ and Fe2+ salts and then adding a base to said aqueous solution until the pH of said aqueous solution is about 10 to form said hemoglobin/Fe3O4 composite, and recovering said hemoglobin/Fe3O4 composite from said aqueous solution; wherein said organic dyes are azo dyes, diazo dyes, arylmethane dyes, xanthene dyes, indole dyes, or mixtures thereof.

US Pat. No. 10,689,266

INTEGRATED DESALINATION-POWER SYSTEM

1. An integrated desalination-power system comprising:a) a desalination system comprising:
i) a water intake configured an intake-depth below a water source surface to collect intake-water;
ii) a desalination processor comprising:
a graphene filter comprising a plurality of graphene layers; and
a structured water system configured prior to the graphene filter;
wherein the structured water system produces water with an elevated concentration of H3O2, wherein the elevated concentration is at least 20% higher than distilled water; and
iii) an intake conduit extending from the water intake to an inlet of the desalination processor that is elevated above the water intake-depth a hydrostatic head height of at least 50 ft;
wherein the desalination processor produces desalinated water from the intake-water;
b) a power system configured to produce electrical power comprising:
i) a turbine configured in the conduit;
wherein the turbine is turned by a flow of water through the inlet conduit to produce electrical power.

US Pat. No. 10,689,265

WATER DESALINIZATION SYSTEMS

1. A purifying water system comprising:a plurality of solar concentrators that receive a sunlight and direct the sunlight toward a plurality of locations by bending a plurality of rays of the sunlight and focusing the plurality of rays of the sunlight onto the plurality of locations;
a plurality of heat collection elements positioned at the plurality of locations having an outer surface conditioned to absorb and convert a solar radiation at a plurality of wavelengths below three one-millionth of a meter to a thermal energy;
the heat collection elements are positioned to induce a state change in a heat-transfer fluid having a salinity of about three and one-half percent; and
a condenser that condenses a portion of the heat-transfer fluid from a gaseous state to a liquid state using a portion of the heat-transfer fluid as a coolant; and
where the plurality of heat collection elements are partially enclosed by the plurality of solar concentrators; and
where at least one of the heat collection elements include a plurality of parabolic chambers that are continuous with a length of the at least one of the heat collection elements, the plurality of parabolic chambers formed by a concave barrier adjacent to and facing a convex barrier each having plurality of perforations along the length of the at least one of the heat collection elements; the concave barrier and the convex barrier having curvatures that induce a flow turbulence through the at least one of the heat collection elements that causes a condensation that facilitate a transfer of a dry steam to the condenser.

US Pat. No. 10,689,264

HYBRID DESALINATION SYSTEMS AND ASSOCIATED METHODS

Gradiant Corporation, Wo...

1. A method for producing a concentrated brine stream, comprising:removing at least a portion of water from a first liquid stream comprising the water and at least one dissolved salt at an initial concentration to produce a first concentrated brine stream comprising water and the at least one dissolved salt at a second concentration higher than the initial concentration of the first liquid stream;
supplying at least a portion of the first concentrated brine stream to a fluidic circuit comprising a vessel and at least one conduit fluidically connected to the vessel, wherein the fluidic circuit establishes a fluidic pathway out of the vessel, through the at least one conduit, and back into the vessel;
removing, within the fluidic circuit, at least a portion of the water from the first concentrated brine stream to produce a second concentrated brine stream comprising water and the at least one dissolved salt at a third concentration higher than the second concentration of the first concentrated brine stream;
recirculating the second concentrated brine stream through at least a portion of the fluidic circuit to remove at least a portion of the water from the second concentrated brine stream, forming a recirculated second concentrated brine stream comprising water and the at least one dissolved salt at a fourth concentration higher than the third concentration of the second concentrated brine stream, wherein recirculating the second concentrated brine stream comprises flowing the second concentrated brine stream out of the vessel, through the at least one conduit, and back into the vessel; and
discharging the recirculated second concentrated brine stream from the fluidic circuit when the recirculated second concentrated brine stream reaches a density of at least about 10 pounds per gallon.

US Pat. No. 10,689,263

WATER VAPOR DISTILLATION APPARATUS, METHOD AND SYSTEM

DEKA Products Limited Par...

1. A system for water dispensing comprising:a housing comprising a first and second portion;
a hot beverage dispenser located separate from the housing;
a water vapor distillation apparatus housed in the first portion of the housing, the water vapor distillation apparatus comprising an evaporator/condenser and a liquid heat exchanger, the evaporator/condenser producing a hot distilled water product, wherein the hot distilled water product is either fed into the liquid heat exchanger and exits as distilled water product or is diverted to the hot beverage dispenser thereby bypassing the liquid heat exchanger;
at least one storage tank housed in the second portion of the housing and fluidly connected to the water vapor distillation apparatus;
a first pump housed in the second portion of the housing and fluidly connected to the at least one storage tank and the hot beverage dispenser; and
a processor,
wherein the distilled water product is stored in the at least one storage tank and the first pump pumps water from the at least one storage tank to the hot beverage dispenser, and
wherein the processor is preprogrammed to schedule the diverting of the hot distilled water product to the hot beverage dispenser at a preprogrammed time.

US Pat. No. 10,689,262

METHOD FOR PRODUCING NICKEL-CONTAINING HYDROXIDE

SUMITOMO METAL MINING CO....

1. A method for producing a nickel-containing hydroxide, the method comprising:a particle growth step of promoting growth of nickel-containing hydroxide particles by neutralization crystallization in an aqueous solution accommodated in an agitation tank;
wherein in the particle growth step, an averaged value of maximum accelerations of flows of streamlines for the aqueous solution is greater than 600 m/s2.

US Pat. No. 10,689,261

PROCESS FOR PRODUCING SODIUM SULPHATE FROM PHOSPHOGYPSUM

1. A process for producing sodium sulphate from phosphogypsum, comprising:a step of lixiviation of phosphogypsum by means of a basic solution comprising a chelating agent so as to obtain a sodium sulphate solution containing metal impurities, wherein at least one part of said metal impurities form complexes with the chelating agent,
at least one first step of filtration of the sodium sulphate solution by a nanofiltration membrane, so as to form a concentrate containing said complexes and a permeate,
a step of evaporation of the permeate so as to form anhydrous sodium sulphate.

US Pat. No. 10,689,260

SALT-ASSISTED ULTRASONIC DISAGGREGATION OF NANODIAMOND

The Curators of the Unive...

1. A method of disaggregating nanodiamond clusters, the method comprising:(a) combining aggregated nanodiamond clusters with a disaggregating agent in a liquid medium comprising a solvent, with the disaggregating agent being present in a concentration above its solubility limit in the solvent to form a mixture of solvent, disaggregating agent, and nanodiamond clusters; and
(b) sonicating the mixture for a time sufficient to produce nanodiamond particles having a median particle size less than the median particle size of the aggregated nanodiamond clusters,
wherein a mass ratio of disaggregating agent to nanodiamond particles in the liquid medium is from about 10:1 to about 100:1.

US Pat. No. 10,689,259

METHOD FOR REPAIRING SURFACE OF CARBON NANOTUBE ARRAY

Tsinghua University, Bei...

1. A method for repairing surface of carbon nanotube array comprising:step (S11), providing a carbon nanotube array and a substrate, the carbon nanotube array being located on a surface of the substrate and comprising a plurality of carbon nanotubes aslant arranged on the surface of the substrate, wherein the carbon nanotube array comprises a top surface and an end surface, the end surface is located on and in direct contact with the surface of the substrate, all carbon nanotubes of the carbon nanotube array are oriented from the end surface to the top surface;
step (S12), placing an adhesive tape on the top surface of the carbon nanotube array, a bond force between the plurality of carbon nanotubes and the substrate is greater than a bond force between the plurality of carbon nanotubes and the adhesive tape; and
step (S13), peeling off the adhesive tape, no carbon nanotube of the carbon nanotube array is separated from the substrate, and the plurality of carbon nanotubes being aslant arranged on the surface of the substrate being pulled up vertically arranged on the surface of the substrate by a bond force of the adhesive tape.

US Pat. No. 10,689,258

METHOD FOR MAKING CARBON NANOTUBE ARRAY

Tsinghua University, Bei...

1. A method for making a carbon nanotube array, the method comprising:providing a substrate, wherein the substrate defines a plurality of through holes and has a first substrate surface and a second substrate surface opposite to the first substrate surface, and the plurality of through holes is spaced apart from each other and extends from the first substrate surface to the second substrate surface;
depositing a catalyst carrier layer on the first substrate surface, wherein the catalyst carrier layer is an aluminum layer, and a thickness of the aluminum layer ranges from about 3 nanometer to about 7 nanometers;
depositing a catalyst layer on the catalyst carrier layer;
providing a gas diffusing unit in a chamber, wherein the gas diffusing unit is a hollow structure and defines a space, a hole and an outlet;
providing a gas supplying pipe in the chamber, wherein the gas supplying pipe comprises a first end and a second end opposite to the first end, the first end extends out of the chamber, and the second end is in the chamber and connected to the hole;
placing the substrate in the chamber and on the gas diffusing unit to cover the outlet; and
growing a carbon nanotube array on the first substrate surface by supplying a carbon source gas and a protective gas into the space via the gas supplying pipe, and heating the substrate.

US Pat. No. 10,689,257

BIO BUCKYPAPER SYNTHESIZED WITH FISH SCALES

King Saud University, Ri...

1. A method of synthesis of bio buckypaper, comprising:synthesizing a bio waste solution from fish scales, wherein the bio waste solution is synthesized by adding about 30 mg to about 75 mg powdered fish scales into a boiling solution of about 15 ml to about 50 ml ethanol and deionized water (1:9 v/v);
mixing a carrageenan with the bio waste solution to provide a first mixture;
adding carbon nanotubes to the first mixture to produce a second mixture;
sonicating the second mixture; and
evaporative-casting the second mixture to produce bio buckypaper.

US Pat. No. 10,689,256

CONDUCTIVE CARBON POWDER, A METHOD FOR THE MANUFACTURING THEREOF AND USE THEREOF

Stora Enso OYJ, Helsinki...

1. A method for manufacturing an electrically conductive carbon powder comprising:i) providing a lignin and at least one additive,
ii) mixing the lignin and the at least one additive to form a mixture,
iii) shaping the mixture to form a shaped body,
iv) performing a thermal treatment of the shaped body in which a first step of the thermal treatment comprises a temperature ramp from room temperature to a temperature of up to 300° C. or less and in which a last step of the thermal treatment comprises a temperature ramp from room temperature to a temperature of up to about 2000° C. or less in an inert atmosphere to provide a conductive carbonized intermediate product, and
v) pulverizing the conductive carbonized intermediate product to provide a conductive carbon powder.

US Pat. No. 10,689,254

METHODS FOR SO2 RECOVERIES FROM SULFUR PLANTS

1. A method for abating the emissions of at least sulfur dioxide present in gases emitted from sulfur recovery plants, comprising:providing at least one first adsorber unit that operates in an adsorption mode to sorb and remove at least the sulfur dioxide out of a tail gas containing sulfur dioxide, and also providing at least one other second adsorber unit that operates in a regeneration mode that receives an acid gas slip stream comprising hydrogen sulfide and also an oxygen-containing gas so as to desorb at least the sulfur dioxide from this said at least one other second adsorber unit to produce a regeneration gas comprising at least sulfur dioxide and hydrogen sulfide, wherein the first and second adsorber units are configured such that these first and second adsorber units are alternately switched between an adsorption mode and a regeneration mode;
passing a tail gas comprising sulfur dioxide through the at least one first adsorber unit so as to sorb and remove the sulfur dioxide out of this tail gas while passing an acid gas slip stream comprising hydrogen sulfide and also an oxygen-containing gas through the at least one other second adsorber unit to regenerate this second adsorber unit and provide an off-gas comprising sulfur dioxide and hydrogen sulfide;
discharging the gas emitted from the at least one first adsorber unit through a stack or a vent, and recycling the off-gas emitted from the at least one second adsorber unit back to a sulfur recovery unit; and
switching the mode of operation of the said at least first adsorber unit so that it receives an acid gas slip stream comprising hydrogen sulfide and also an oxygen-containing gas and is regenerated, and switching the mode of operation of the said at least second adsorber unit so that it receives a tail gas comprising sulfur dioxide and removes at least the sulfur dioxide out of this tail gas, wherein the adsorbent material within the at least one first adsorber unit and/or the at least one second adsorber unit is selected from the group consisting of alumina catalyst, activated alumina catalyst, alumina/titania catalyst, titania catalysts, iron with nickel, chromium, cobalt with molybdenum, molybdenum, manganese, cobalt, and one or more combinations thereof.

US Pat. No. 10,689,253

PROPYLENE GLYCOL REFORMING

DIEHL AEROSPACE GMBH, Ue...

1. A reformer reactor for the reforming of propylene glycol, comprising a reactor housing having an inlet and an outlet and containing a catalyst comprising a support material and a catalytic constituent, wherein the support material is composed of at least one metal oxide, and the catalytic constituent comprises at least one of Ru, Rh, Pd, Pt and Ni, wherein plates are accommodated in the reactor housing and the catalyst has been applied as surface coating to at least one of the plates, the plates having channels and/or flow-directing elements, and wherein the plates are arranged horizontally, one above the other and parallel to each other.

US Pat. No. 10,689,252

MONODISPERSE SINGLE-WALLED CARBON NANOTUBE POPULATIONS AND RELATED METHODS FOR PROVIDING SAME

Northwestern University, ...

1. A population of loose single-walled carbon nanotubes, wherein greater than about 90% of the population is metallic single-walled carbon nanotubes and the single-walled carbon nanotubes are unmodified chemically or structurally.

US Pat. No. 10,689,251

MEMS DEVICE INCLUDING A CAPACITIVE PRESSURE SENSOR AND MANUFACTURING PROCESS THEREOF

STMICROELECTRONICS S.R.L....

1. A MEMS device comprising:a first semiconductor die including a chamber, the first semiconductor die including a transducer and a column in the chamber; and
a second semiconductor die coupled to the first semiconductor die, a first surface of the second semiconductor die facing the column and forming a membrane, wherein the column and the membrane form plates of a capacitive pressure sensor, and wherein the first surface of the second semiconductor die includes an absorber element facing the transducer.

US Pat. No. 10,689,250

MEMS COMPONENT AND PRODUCTION METHOD FOR A MEMS COMPONENT

INFINEON TECHNOLOGIES AG,...

1. A production method for a double-membrane MEMS component, comprising the following steps:providing a layer arrangement on a carrier substrate, wherein the layer arrangement has a first and second membrane structure spaced apart from one another and a counterelectrode structure arranged therebetween, wherein a sacrificial material is arranged in an intermediate region between the counterelectrode structure and the first and second membrane structures respectively spaced apart therefrom, and wherein at least one of the first membrane structure or the second membrane structure has an opening structure to the intermediate region with the sacrificial material, and
partly removing the sacrificial material from the intermediate region in order to obtain a mechanical connection structure comprising the sacrificial material between the first and second membrane structures, wherein the mechanical connection structure is mechanically coupled between the first and second membrane structures and is mechanically decoupled from the counterelectrode structure, and wherein the mechanical connection structure is convexly contoured and vertically symmetrical about an intersecting horizontal plane of symmetry parallel to the first and second membrane structures.

US Pat. No. 10,689,249

SEMICONDUCTOR DEVICE PACKAGE INCLUDING A WALL AND A GROUNDING RING EXPOSED FROM THE WALL

ADVANCED SEMICONDUCTOR EN...

1. A semiconductor device package, comprising:a carrier;
a wall disposed on a top surface of the carrier;
a cover having a bottom surface including a portion protruding from the bottom surface of the cover, the protruding portion of the cover contacting a top surface of the wall to define a space; and
a sensor element positioned in the space;
a bonding wire connecting the sensor element to the top surface of the carrier defining a bottom of the space,
wherein the wall has an outer lateral surface facing away from the space, the protruding portion of the cover has a first lateral surface facing toward the space and a second lateral surface facing away from the space, and wherein the second lateral surface of the protruding portion of the cover is substantially coplanar with the outer lateral surface of the wall,
further comprising at least one conductive element exposed from the outer lateral surface of the wall, the conductive element is a grounding ring surrounding the space; and
a reinforced element contacting the bottom surface of the cover and the protruding portion of the cover, wherein the reinforced element comprises a bottom surface parallel to the bottom surface of the cover and a lateral surface parallel to the first lateral surface of the protruding portion of the cover.

US Pat. No. 10,689,248

SEMICONDUCTOR DEVICE PACKAGE AND METHOD OF MANUFACTURING THE SAME

ADVANCED SEMICONDUCTOR EN...

1. A semiconductor device package, comprising:a substrate defining an opening:
a support structure disposed on the substrate;
an electronic component disposed on the support structure; and
wherein the electronic component is a microelectromechanical systems (MEMS) device; and
an adhesive disposed between the substrate and the electronic component and covering the support structure,
wherein a hardness of the support structure is less than a hardness of the electronic component.

US Pat. No. 10,689,247

METHOD AND STRUCTURE FOR CMOS-MEMS THIN FILM ENCAPSULATION

Taiwan Semiconductor Manu...

1. A micro-electromechanical system (MEMS) device, comprising:an insulating layer over a substrate, the insulating layer comprising a plurality of first layers and a plurality of second layers interleaved with the plurality of first layers;
a first plurality of conductive vias in the plurality of first layers of the insulating layer;
a first plurality of metal features in the plurality of second layers of the insulating layer;
a first void region in the insulating layer, the first void region being an empty space, the first void region comprising a first set of openings in the plurality of first layers and a second set of openings in the plurality of second layers;
a first contact pad disposed in the insulating layer at a top surface of the insulating layer; and
a first sealing structure over the first void region, the first sealing structure sealing the first void region.

US Pat. No. 10,689,246

LOW CONTACT RESISTANCE SEMICONDUCTOR STRUCTURE AND METHOD FOR MANUFACTURING THE SAME

SEMICONDUCTOR MANUFACTURI...

1. A semiconductor device, comprising:a bottom substrate;
a sacrificial layer on the bottom substrate and including a first opening exposing a first portion of the bottom substrate and a second opening exposing a second portion of the bottom substrate;
a top substrate on the sacrificial layer and on the second opening forming a cavity;
a first metal layer on the top substrate and on the exposed first portion of the bottom substrate;
an adhesive layer on the first metal layer covering an upper surface and side surfaces of the first metal layer; and
a second metal layer on the adhesive layer defining one or more pads.

US Pat. No. 10,689,245

VERTICALLY STACKED NANOFLUIDIC CHANNEL ARRAY

INTERNATIONAL BUSINESS MA...

1. An apparatus, comprising:a semiconductor substrate;
a dielectric layer adjacent to the semiconductor substrate, the dielectric layer comprising a first nanofluidic channel and a second nanofluidic channel, wherein the second nanofluidic channel is located between the first nanofluidic channel and the semiconductor substrate, wherein the dielectric layer forms a first side of the first nanofluidic channel and a second side of the first nanofluidic channel; and
a first silicon layer that forms a third side of the second nanofluidic channel, wherein the third side of the second nanofluidic channel is parallel with the semiconductor substrate, and wherein the dielectric layer is provided on a plurality of sides of the first silicon layer.

US Pat. No. 10,689,244

ASSISTANCE LEVER FOR A FUEL NOZZLE

1. An assistance lever that assists a user to operate a fuel nozzle at a fuel dispenser, comprising:a fulcrum post positionable on a top ridge of the fuel nozzle, wherein the fulcrum post defines a bottom groove configured to receive the top ridge of the fuel nozzle;
a handle post;
a support arm connected between the fulcrum post and the handle post such that the handle post is positionable beneath a handle of the fuel nozzle; and
a press member attached to the fulcrum post and positioned to turn the assistance lever about the fulcrum post when pressed by the user such that the handle post presses the handle of the fuel nozzle.

US Pat. No. 10,689,243

METERED DISPENSING DEVICE FOR PLANT EXTRACTS

1. A metered dispensing device for plant extracts, the device comprising:a main body having an inner volume for holding plant extract;
a rotatable dial operably coupled on an end of the main body;
a dispensing end located on an end of the main body opposite the rotatable dial;
a dispensing tip coupled to the dispensing end;
a dispensing mechanism including a plunger moveable along the length of the main body in response to rotation of the dial, wherein the plunger comprises a plunger rod coupled to the dial and a plunger end, comprising a base portion and an extended portion, coupled to the plunger rod, wherein rotation of the dial rotates the plunger rod, wherein the plunger pushes plant extract from the inner volume out the dispensing tip; and
a feedback system providing tactile and audible feedback after a predetermined amount of plant extract has been dispensed through the dispensing tip.

US Pat. No. 10,689,242

WIRELESS CONTROL SYSTEM FOR DISPENSING BEVERAGES FROM A BOTTLE

Berg Company, LLC, Monon...

1. A method for dispensing beverages bottles comprising:selecting a cocktail by a person via a user input device;
obtaining a designation of a plurality of liquor ingredients from an electronic memory in response to the cocktail that was selected;
transmitting, wirelessly, the designation of the plurality of liquor ingredients from a control unit to a server interface carried by the person;
transmitting, wirelessly, a dispensing command from the server interface to a given pour spout attached to a bottle containing the respective liquor ingredient for each of the plurality of liquor ingredients; and
responding to the dispensing command by opening a valve of the given pour spout through which the respective liquor ingredient flows from the bottle.

US Pat. No. 10,689,241

SEMI-AUTOMATED BEVERAGE DISPENSING MACHINES AND METHODS

Cornelius, Inc., Osseo, ...

1. A food product dispensing machine comprising:a controller;
a user interface via which an operator can input a beverage order to the controller, the beverage order comprising a plurality of beverages including at least one beverage contained in a first cup and at least one beverage contained in a second cup, wherein the first cup is sized different than the second cup;
a first cup housing configured to hold a plurality of the first cups;
a first dispense sensor configured to sense a number of the first cups dispensed from the first cup housing;
a second cup housing configured to hold plurality of the second cups;
a second dispense sensor configured to sense a number of the second cups dispensed from the second cup housing; and
an indicator configured to indicate a number of the first cups that needs to be dispensed according to the beverage order and a number of the second cups that needs to be dispensed according to the beverage order;
wherein the controller is configured to control the indicator to indicate in real time the numbers of first and second cups that need to be dispensed according to the beverage order.

US Pat. No. 10,689,240

AUTOMATED BEVERAGE DISPENSING MACHINES

CORNELIUS, INC., Osseo, ...

1. A beverage dispensing machine that extends from top to bottom in a vertical direction, from right side to left side in a width direction that is perpendicular to the vertical direction, and from front to back in a depth direction that is perpendicular to the vertical direction and perpendicular to the width direction, the beverage dispensing machine comprising:a countertop that extends in the width direction and in the depth direction;
a conveyor on the countertop, wherein the conveyor carries a plurality of cup holders around a track having a front side oriented towards the front of the beverage dispensing machine and a back side oriented towards the back of the beverage machine, wherein the front side is accessible by an operator to remove cups from the plurality of cup holders;
a cup tower located above the countertop in the vertical direction, the cup tower comprising a plurality of cup dispenser tubes that are each configured to hold a respective stack of cups, wherein the cup tower is rotatable about a vertical cup tower axis;
a cup grabber located above the countertop and adjacent to the cup tower and between the back side of the track and the back of the beverage dispensing machine, wherein the cup grabber is movable up and down in the vertical direction into and between a raised position in which the cup grabber is positioned to grab a cup from one of the stacks of cups, a lowered position in which the cup grabber is positioned to place a cup into one of the plurality of cup holders, and an intermediate position in between the raised and lowered position wherein the cup grabber is spaced apart from and between the cup tower and the plurality of cup holders in the vertical direction so that the tower is free to rotate about the cup tower axis and the conveyor is free to carry the plurality of cup holders around the track;
wherein each cup holder in the plurality of cup holders comprises a base, sidewalls extending upwardly from the base, and a front window formed in the sidewalls having an open top, wherein the front window is oriented away from a center of the track, the front window oriented and sized to facilitate manual grasping and removal of a cup from the cup holder when the cup holder is located on the front side of the track; and
an ultrasonic sensor that senses whether a cup is present in each of the plurality of cup holders via the front window in the cup holder, and further comprising a controller that is configured to control the conveyor based upon an output from the sensor.

US Pat. No. 10,689,238

ADAPTABLE INSULATED GALLEY CART CARBONATED BEVERAGE DELIVERY SYSTEM

The Boeing Company, Chic...

1. A galley cart carbonated beverage dispensing system comprising:a housing defining a cavity, said housing adapted to support a beverage keg within the cavity and a carbonation cylinder within the cavity;
a dispensing tower vertically translatable telescopically from a receiver extending from the cavity through a top of the housing and retractable into the receiver through the top of the housing; and
a spigot extending from the dispensing tower and translating with the dispensing tower through a slot extending from the receiver in the top of the housing.

US Pat. No. 10,689,237

NET WEIGHT FILLING MACHINE WITH VOLUMETRIC PUMP

WEIGHTPACK S.r.l., Goito...

1. A machine for filling containers with a product, comprising:a carousel for moving a plurality of said containers;
a plurality of filling valves, each filling valve being positioned above a clamp;
a distribution duct connecting said filling valves with a distribution manifold, wherein said distribution duct having the product includes a filling pressure;
a feed duct intercepted by a volumetric pump, wherein said volumetric pump moves the product with a discharge pressure greater than said filling pressure, and an adjustment member for adjusting a feed pressure of the product, said adjustment member being positioned along the feed duct, downstream of the volumetric pump.

US Pat. No. 10,689,236

OPENER

Jen Pearson, Oakland, CA...

1. An opener comprising:a rigid, parallelepiped body having rhombus sides and two end portions at opposite ends of the rigid, parallelepiped body, wherein each end portion is favorably sized to hold a bottle cap, and each end portion has a first member configured to engage a crown of the bottle cap and a second member configured to cooperate with a top surface of the bottle cap,
wherein the opener is configured to remove a bottle cap from a bottle by engaging the first member of a first end portion of the two end portions with a crown of the bottle cap and engaging the second member of the first end portion with a top surface of the bottle cap about a fulcrum axis for disengaging the cap from a mouth of the bottle upon exertion of an effort force on the end portion opposite the first end portion.

US Pat. No. 10,689,235

PRY DOLLIE

John Allen Dongarra, W.V...

1. A hand tool having said tool comprising a handle, a foot with a first and second end with said first end attached to said handle, said second end having a tube wherein said foot has a curved profile and a flat arcuate surface with said tube extending across said second end, and a pushing surface face comprising a surface including bracket being moveably attached to said tube.

US Pat. No. 10,689,234

PULLEY SYSTEM WITH SAFETY LOCK

X Development LLC, Mount...

1. A pulley system for lifting a load using a cord, the pulley system comprising:a first stage;
a second stage mechanically coupled to the first stage at a pivot point, the first and second stages being independently rotatable about a stage axis passing through the pivot point;
a first pulley attached to the first stage and the second stage at the pivot point, the first pulley being rotatable about a first pulley axis coinciding with the stage axis;
a second pulley attached to the second stage, the second pulley being rotatable about a second pulley axis parallel to but displaced from the stage axis;
a third pulley attached to the second stage, the third pulley being rotatable about a third pulley axis parallel to but displaced from the stage axis and the second pulley axis;
a pair of braking elements attached to the first stage, a first of the braking elements being positioned between the first and second pulleys and a second of the braking elements being positioned between the first and third pulleys; and
wherein an even tension on the cord aligns the first stage and the second stage in a neutral arrangement in which both braking elements are disengaged from the cord, and an uneven tension on the cord rotates the first stage with respect to the second stage about the stage axis so that the first braking element engages the cord at the second pulley or the second braking element engages the cord at the third pulley.

US Pat. No. 10,689,233

CABLE SPOOL LIFTING AND INVERSION BAR AND METHODS OF UTILISATION THEREOF

LIBIP HOLDINGS PTY LTD, ...

1. A cable spool lifting and inversion bar for repositioning a cable spool comprising a length and annuli having an annular radius between horizontal and vertical orientations, the bar comprising:a straight frame; and
an orthogonal shaft bisecting the frame into long and short ends, the shaft and the long end comprising a strain taking connections at respective distal ends thereof and wherein:
the shaft is longer than the length so as to be able to protrude through a core of the cable spool in use such that the shaft strain taking connection extends therebeyond;
the long end is longer than the radius so as to be able to extend beyond an annular edge of the spool in use;
the short end has the same length as the radius or is shorter than the radius so as to not extend substantially beyond the annular edge of the spool in use; and
for the vertical orientation, the frame defines:
an upper surface; and
a widthwise stance such that, in use the spool is able to stand atop the frame upper surface and be freely laterally supported thereby.

US Pat. No. 10,689,232

FLOOR COVERING OF A PASSENGER CONVEYOR

Inventio AG, Hergiswil (...

1. A floor covering of an entry region of a passenger conveyor designed as an escalator or a moving walkway, the floor covering comprising:a floor covering support,
a first covering element and at least one adjoining covering element configured to close an opening in an underfloor space in the passenger conveyor at least with the first covering element and the at least one adjoining covering element supported on the floor covering support such that it is flush with the surrounding flooring that can be walked on,
at least one device which predetermines a single-possible, correct installation position of the first covering element and the at least one adjoining covering elements on the floor covering support arranged at least in the region of the first covering element and the at least one adjoining covering element the at least one device configured such that, in the correct installation position, the first covering element and the at least one adjoining covering element are arranged flush with the floor covering support and, in an incorrect installation position, at least part of the at least one adjoining covering element is arranged in a visibly protruding manner on the floor covering support due to the at least one device, wherein the at least one device comprises a positioning element configured to be brought into an interlocking operative connection with the floor covering support or with the first covering element by moving the first covering element on the floor covering support.

US Pat. No. 10,689,231

BELT SAFETY DEVICE AND PEOPLE CONVEYOR WITH A BELT SAFETY DEVICE

OTIS ELEVATOR COMPANY, F...

1. Belt safety device for monitoring a drive belt, the belt safety device comprising:a sensor wheel configured to be driven by the drive belt;
a sensor surface;
an indicator element extending eccentrically from the sensor wheel and moving along a path (P) at the sensor surface when the sensor wheel rotates; and
an evaluation unit, which is configured for determining the path (P) of the indicator element moving along the sensor surface for detecting damage of the drive belt;
wherein the indicator element comprises an electrical conductor contacting the sensor surface;
wherein the sensor surface has an electric resistance varying in at least one dimension.

US Pat. No. 10,689,230

ELEVATOR SYSTEM SUSPENSION MEMBER TERMINATION WITH IMPROVED PRESSURE DISTRIBUTION

OTIS ELEVATOR COMPANY, F...

1. A termination device for a suspension member of an elevator system comprising:a housing; and
a wedge assembly disposed in the housing, the wedge assembly interactive with the suspension member to apply a clamping force to the suspension member in response to an axial load acting on the suspension member, the wedge assembly including a compressible cushion configured to increase uniformity of the clamping force applied to the suspension member by the wedge assembly;
wherein the wedge assembly includes:
an interface plate configured to abut the suspension member; and
a wedge abutting an inner housing surface;
wherein the compressible cushion is disposed between the interface plate and the wedge, the compressible cushion abutting both the interface plate and the wedge.

US Pat. No. 10,689,229

ELEVATOR SYSTEM SUSPENSION MEMBER TERMINATION

OTIS ELEVATOR COMPANY, F...

1. An elevator system comprising:a hoistway;
an elevator car suspended in the hoistway via one or more suspension members;
a counterweight suspended in the hoistway via the one or more suspension members to balance operation of the elevator car;
a bedplate extending across the hoistway;
a machine disposed at the bedplate to drive the one or more suspension members along the hoistway, driving motion of the elevator car and/or counterweight along the hoistway, the machine including a machine frame secured to the bedplate;
a suspension member termination disposed at the machine frame, to secure an end of the one or more suspension members; wherein a termination body is formed integral to the machine frame, and a termination wedge inserted into the termination body to secure the one or more suspension members at the termination body.

US Pat. No. 10,689,228

ELEVATOR SYSTEM EVALUATION DEVICE

OTIS ELEVATOR COMPANY, F...

1. An evaluation device for use in an elevator system including a hoistway; a guide rail configured to guide an elevator car in the hoistway; a stator mounted on the guide rail, the stator including a plurality of coils; a plurality of permanent magnets mounted on the elevator car; an evaluation device separate from the elevator car, the evaluation device comprising:a self-propelled drive unit including a motor secondary configured to travel along the stator; and
at least one diagnostic sensor.

US Pat. No. 10,689,227

ELECTRIC LINEAR MOTOR

Kone Corporation, Helsin...

12. The transport system according to claim 1, wherein the mover includes one or more movers each connected to a respective elevator car, the stator beam extends longitudinally along an elevator shaft and does not include any of the at least one winding and the at least one permanent magnet fixed thereto such that along a length of the elevator shaft only the one or more movers connected to the respective elevator car includes the at least one winding and the at least one permanent magnet.

US Pat. No. 10,689,226

POSITION DETERMINING SYSTEM FOR MULTICAR ROPELESS ELEVATOR SYSTEM

OTIS ELEVATOR COMPANY, F...

1. An elevator system comprising:an elevator car configured to travel in a lane of an elevator shaft;
a linear propulsion system configured to impart force to the elevator car, the linear propulsion system comprising:
a first part mounted in the lane of the elevator shaft; and
a second part mounted to the elevator car configured to co-act with the first part to impart movement to the elevator car;
a plurality of car state sensors disposed within the lane and operable to determine a state space vector of the elevator car within the lane;
a sensed element disposed on the elevator car, wherein each of the plurality of car state sensors is configured to detect the sensed element when the elevator car is in proximity to the respective car state sensor; and
a control system operable to apply an electrical current to at least one of the first part and the second part,
wherein the plurality of car state sensors are in communication with the control system and the linear propulsion system to provide state space vector data thereto,
and an elevator car identification mechanism arranged on the elevator car and configured to be detected by the plurality of car state sensors, wherein each of the plurality of car state sensors is configured to detect an identity of the elevator car based on the elevator car identification mechanism such that the identity of the specific elevator car, the location of the specific elevator car within the lane, and state space vector data are known by the control system.

US Pat. No. 10,689,225

PREDICTIVE ANALYTICS TO DETERMINE ELEVATOR PATH AND STAGING

International Business Ma...

1. A method for determining an optimal path for an elevator, the method comprising:receiving, by one or more processors, information, wherein the information includes badge access data, facial recognition sensor data, weight sensor data, historical elevator usage data, mass transit data, weather data, courier data, social media data associated with a user, and calendar entries associated with the user, indicating one or more locations within a building;
analyzing, by one or more processors, the received information, wherein analyzing the received information comprises:
predicting, by one or more processors, elevator utilization and elevator traffic for at least one floor throughout a day, based on historical usage trends associated with the received information;
predicting, by one or more processors, movement of the user within the building, based on the calendar entries and the social media data;
determining, by one or more processors, occupancy ratio and predicting elevator usage, based on data obtained from badge, closed circuit television, and facial recognition sources;
determining, by one or more processors, a time of courier arrival and a destination within the building to predict elevator usage;
predicting, by one or more processors, occupancy related to road closures and difficulties to make it to the building that arise due to inclement weather;
determining, by one or more processors, a location to send an elevator within the building to minimize movement of the elevator, based on the analyzed information; and
causing, by one or more processors, the elevator to move to the location.

US Pat. No. 10,689,224

ADJUSTABLE TURNTABLE FOR COILS AND SPOOLS

1. An adjustable turntable for receiving a coiled wire or a spool about which a wire or cable is wound, the adjustable turntable, comprising:a turnable that includes a turntable having a top surface that includes a plurality of measurement circles arranged concentrically and that defines a pair of radial channels, said turnable including a plurality of posts that are length adjustable and positioned in said pair of radial channels, respectively, and configured to receive the spool;
wherein each post includes a post slide portion correspondingly shaped to slide in a respective radial channel and a bottom surface;
a base having a pair of support members each having a longitudinal configuration fixedly attached to one another in a transverse arrangement so as to form conjoined members, said conjoined members defining a bore;
a hub complementary to and received in said bore and operable to receive a flange depending from said turntable for providing freewheeling rotation of said turntable.

US Pat. No. 10,689,223

CABLE REEL AND REEL CARRYING CADDY

PERFECTVISION MANUFACTURI...

1. A caddy system for enclosing, transporting and dispensing cable, the caddy system comprising:a clamshell housing for enclosing a tubular drum that holds a coil of electrical cable;
inserted in each end of the drum is a tubular projection of an end cap;
opposite the tubular projections are receivers within each end cap;
rotatably inserted in the receivers are first and second plugs;
a key irrotatably inserted in the housing is irrotatably inserted in the first plug; and,
the second plug is irrotatably inserted in the housing such that the drum and end caps rotate about the plugs.

US Pat. No. 10,689,222

SHEET PROCESSING APPARATUS AND IMAGE FORMING SYSTEM INCORPORATING THE SAME

RICOH COMPANY, LTD., Tok...

1. A sheet processing apparatus comprising:a rotatable pressing member including a pressing portion in a range in a rotation direction of the pressing member, the pressing portion configured to press a folded portion of a sheet;
a guide opposite the pressing member; and
a contact member an end of the pressing member in an axial direction of the pressing member, the contact member configured to contact the guide, and the contact member being rotatable with respect to the pressing member.

US Pat. No. 10,689,221

SHEET PROCESSING APPARATUS AND IMAGE FORMING SYSTEM

RICOH COMPANY, LTD., Tok...

1. An image forming system comprising:an image forming apparatus configured to form an image on a sheet; and
a sheet processing apparatus configured to stitch a bundle of sheets, on which an image is formed by the image forming apparatus,
the sheet processing apparatus including
a sheet stacker configured to stack thereon multiple sheets;
a staple-containing stitching unit configured to stitch the sheets using one or more staples;
a staple-free stitching unit configured to stitch the sheets without using a staple;
a first drive source configured to drive the staple-containing stitching unit;
a second drive source separate from the first drive source and configured to drive the staple-free stitching unit;
a frame including at least a first frame member and a second frame member respectively disposed outside both ends of the sheet stacker in a direction perpendicular to a sheet conveying direction in which the sheets enter the sheet stacker, the first frame member being disposed on a side where the staple-containing stitching unit is disposed, the second frame member being disposed on a side where the staple-free stitching unit is disposed, and the second frame member including a hole section; and
an outer cover including at least a first cover member and a second cover member respectively disposed further outside the first and second frame members in the direction perpendicular to the sheet conveying direction, wherein
the staple-free stitching unit is disposed on a back side of the sheet processing apparatus, and the staple-containing stitching unit is disposed on a front side of the sheet processing apparatus,
at least a part of the first cover member is openable and closable, and at least a part of the second cover member is detachable, and
the staple-free stitching unit located between the second frame and the second cover member when the staple-free stitching unit stands by at a home position.

US Pat. No. 10,689,220

MEDIA-SHEET STACKING SYSTEMS

Hewlett-Packard Developme...

1. A media-sheet stacking system for stacking media sheets on an output tray for a device, the media-sheet stacking system comprising:a kicker comprising a tip to advance a media sheet along the output tray by pushing a trailing edge of the media sheet exiting the device, wherein the kicker is moveable between a retracted position to an extended position to eject the media sheet onto the output tray;
an output roller to push the media sheet to the output tray;
a sensor to sense presence of the media sheet, wherein the kicker is to retract from the extended position to the retracted position responsive to the sensor ceasing to detect the presence of the media sheet;
a moveable surface arranged to face the output tray across a space receiving media sheets exiting the device; and
a drive mechanism comprising a roller and to drive the moveable surface in a direction of advance of the media sheet along the output tray.

US Pat. No. 10,689,219

SHEET DISCHARGE APPARATUS AND IMAGE FORMING APPARATUS INCLUDING THE SAME

Canon Kabushiki Kaisha, ...

1. A sheet discharge apparatus comprising:a main tray on which a sheet is to be stacked and which is pivotable between a closed position at which the main tray is closed with respect to a main body of the sheet discharge apparatus and an opened position at which the main tray is opened with respect to the main body of the sheet discharge apparatus;
a discharge unit configured to discharge the sheet onto the main tray in a case where the main tray is at the closed position; and
an expansion tray configured to expand a stacking area of the main tray, wherein the expansion tray is provided to the main tray and movable between a storage position at which the expansion tray is stored in the main tray and an expansion position at which the expansion tray is slid from the storage position in a sheet discharge direction and expands the stacking area,
wherein, at the expansion position, the expansion tray is pivotable on a pivot center provided to the expansion tray, in a vertically upward direction, by a predetermined angle, independently of the main tray,
wherein the pivot center of the expansion tray is provided at a position closer to an upstream edge of the expansion tray than a downstream edge of the expansion tray in the sheet discharge direction, and
wherein a direction in which the expansion tray is pivoted in the vertically upward direction is the same as a direction in which the main tray is pivoted from the closed position to the opened position,
wherein, in a case where the expansion tray is pivoted in the vertically upward direction from the expansion position, the expansion tray is restricted from further rotation in the vertically upward direction.

US Pat. No. 10,689,218

PRINTING APPARATUS

MIMAKI ENGINEERING CO., L...

1. A printing apparatus, comprising:a feeding roller configured to feed and supply a medium from a roll of the medium;
a printing portion configured to make a print on the medium supplied from the feeding roller;
a conveyance portion configured to convey the medium to the printing portion,
the conveyance portion including a rotation roller configured to sandwich the medium and rotate along with conveyance of the medium;
wherein the printing apparatus further comprises:
a brake device, being disposed separately from the rotation roller on a conveyance path of the medium between the rotation roller and the feeding roller, and being configured to apply a force against a tension generated by the conveyance portion to the medium.

US Pat. No. 10,689,217

FILM ROLL, METHOD OF PRODUCING THE SAME, AND METHOD OF TESTING THE SAME

SUMITOMO CHEMICAL COMPANY...

1. A film roll comprising:a cylindrical member having one end part and the other end part, the one end part being smaller in material thickness than the other end part; and
a film which is wound around an outer circumferential surface of the cylindrical member, the film having a thickness that is larger toward the one end part than it is toward the other end part with respect to a widthwise axis.

US Pat. No. 10,689,216

INSPECTION DEVICE AND INSPECTION METHOD

KABUSHIKI KAISHA TOSHIBA,...

1. An inspection device, comprising:a transmitter configured to emit an ultrasonic wave;
a receiver;
a feeder configured to cause an inspection object to move relative to the transmitter and the receiver in a space between the transmitter and the receiver; and
a processor configured to process a received signal corresponding to the ultrasonic wave obtained by the receiver,
in a first state in which the inspection object includes a first region and a second region, the first region includes a foreign object, and the second region does not include the foreign object, the received signal includes
a first signal level in a first interval when at least a portion of the first region passes through the space,
a second signal level in a second interval when at least a portion of the second region passes through the space, and
a third signal level in a third interval when the inspection object does not pass through the space,
the processor is configured to detect the foreign object by detecting at least one extreme value occurring in the received signal in a fourth interval between the first interval and the second interval,
wherein an absolute value of the third signal level is greater than an absolute value of the second signal level, and
the absolute value of the second signal level is greater than an absolute value of the first signal level.

US Pat. No. 10,689,215

AUTOMATIC CLOTH FEEDER

TOTOFOLDER MANUFACTURING ...

1. An automatic cloth feeder that conveys cloth with a feeding conveyor, detects a trailing end of the cloth to hold the trailing end with a keeping-transferring part in the process of conveyance, and feeds the trailing end of the cloth into a process as a leading end,wherein the keeping-transferring put has a pair of unfolding members provided as one set are provided on an outlet side of the feeding conveyor in order to hold the left and right trailing ends of the cloth, and
wherein the keeping-transferring part has holding pieces that are opened and closed substantially to the right and the left as seen from the top or from the front, is in a positional relationship of approaching lifting means but not coming into contact with the lifting means in an open state, and is configured so as to hold the trailing ends of the cloth located at the position of the lifting means in a closed state.

US Pat. No. 10,689,213

VEHICLE RESTRAINTS WITH A BARRIER HAVING ROTATIONAL AND TRANSLATIONAL MOTION

RITE-HITE HOLDING CORPORA...

1. A vehicle restraint to block and release a vehicle at a loading dock, the vehicle restraint comprising:a carriage frame to move relative to a main track, the carriage frame including a secondary track defining a front end and a rear end;
a track follower movably coupled to the carriage frame via the secondary track, the track follower movable between the front end and the rear end of the secondary track; and
a barrier coupled to the track follower, the barrier to rotate relative to the carriage frame between a raised position and a stored position in response to the track follower moving along a first portion of the secondary track, and the barrier to translate relative to the carriage frame between the raised position and a capturing position in a direction toward the main track to restrain a rear impact guard of the vehicle in response to the track follower moving along a second portion of the secondary track different than the first portion.

US Pat. No. 10,689,212

APPARATUS FOR LOADING AND UNLOADING OF FREIGHT

Tata Consultancy Services...

1. An apparatus (11) comprising:a mobile base platform (24) includes a front end and a rear end;
a telescopic railing (54) includes a front end a tail end, wherein the tail end of the telescopic railing (54) is mounted on the front end of the mobile base platform (24);
a telescopic conveyor (56) coupled to the front end of the telescopic railing, includes a front end and a tail end placed parallel to the telescopic railing (54), wherein the tail end of the telescopic conveyor (56) includes a plurality of hydraulic legs to adjust the tail end of the telescopic conveyor (56) in relation with the mobile base platform (24);
a mechanical connector (64) adapted to connect the front end of the telescopic conveyor (56) and the front end of the telescopic railing (54); and
a robotic arm (26B0 mounted on a robotic mounting plate (62) coupled to the front end of the telescopic railing (54), wherein the robotic arm (26B) lifts a unit load (28) among a plurality of unit loads (28) of a freight and positions the lifted unit load (28) on a target position.

US Pat. No. 10,689,211

PIPE FOR CONVEYING ABRASIVE MATERIALS SUCH AS CONCRETE, APPARATUS AND METHOD FOR PRODUCING SAID PIPE

VALME S.R.L.-UNICO SOCIO,...

1. Method for producing a tube or curved segment of tube for transferring abrasive materials, comprising a curved external tubular element and a curved internal tubular element made of a material having a resistance to wear greater than that of the curved external tubular element and having a cross section such as to cover at least part of the internal surface of the curved external tubular element, wherein the method provides to make said curved external tubular element and said curved internal tubular element separately,the method comprising:
heating said curved external tubular element at least to around its temperature of deformation,
inserting said curved internal tubular element inside said curved external tubular element after said curved external tubular element is heated,
closing a mold, and applying a pressure to an external surface of the curved external tubular element against an external surface of the curved internal tubular element, making use of the heated condition of the curved external tubular element to form the curved external tubular element on the exact geometry of the curved internal tubular element, and
opening the mold and cooling with consequent shrinkage of the curved external tubular element on the curved internal tubular element.

US Pat. No. 10,689,210

MULTILAYER HYDRODYNAMIC SHEATH FLOW STRUCTURE

1. A microfabricated sheath flow structure for suspending a stream of particles in a sheath fluid, comprising:a primary sheath flow channel for conveying a sheath fluid, wherein the primary sheath flow channel has a width and a height;
a sample inlet intersecting the primary sheath flow channel at a sample injection site for injecting a stream of particles into the sheath fluid conveyed through the primary sheath flow channel;
a primary focusing region downstream of the sample injection site that focuses the stream of particles in at least a vertical direction; and
a secondary focusing region downstream of the primary focusing region that focuses the stream of particles in a horizontal direction and a vertical direction,
wherein a height of the primary sheath flow channel is reduced in the secondary focusing region to focus in the vertical direction.

US Pat. No. 10,689,209

NONCONTACT SUPPORT PLATFORM WITH EDGE LIFTING

CORE FLOW LTD., Daliyat ...

1. A noncontact support platform comprising:a plurality of pressure ports distributed on a surface of a table, each pressure port connected to a pressure source to cause fluid to flow outward through the pressure port;
a plurality of vacuum ports distributed on the surface of the table, each vacuum port connected to a vacuum source to cause fluid to flow inward through the vacuum port, the outward flow through the pressure ports and the inward flow through the vacuum ports configured to form a fluid cushion to support a workpiece at a nonzero distance from the table; and
a plurality of channels, each channel connecting at least two of the vacuum ports to enable flow of fluid between the connected vacuum ports via the channel, the plurality of channels being oriented non-perpendicularly to a direction of transport of the workpiece along the noncontact support platform such that when one of the connected vacuum ports is covered by an edge of the workpiece and the other connected vacuum port is not covered by the workpiece, a suction force that is exerted by the connected vacuum ports on the edge is weaker than the suction force that is exerted by the connected vacuum ports on a part of the workpiece where both of the connected vacuum ports are covered.

US Pat. No. 10,689,208

CONVEYING APPARATUS

LISEC AUSTRIA GMBH, Seit...

1. A method for conveying panel-shaped components, the method comprising:lifting panel-shaped components disposed in an essentially vertical conveying plane out of a first conveying path transversely to a conveying direction into at least one second conveying path; and
lowering the lifted panel-shaped components transversely to the conveying direction into the first conveying path,
wherein the panel-shaped components are moved in the conveying paths at speeds that differ from one another, and
at least one of the components is processed in at least one region that is located in the first conveying path.

US Pat. No. 10,689,207

COMPACT COLLATOR, SYSTEM AND METHOD OF USE

Delkor Systems, Inc., St...

1. A compact collator comprises:a laner, the laner having a first movable conveyor for conveying product containers through the laner, the laner defining an infeed area,
the infeed area comprising a first infeed sensor positioned at an entrance to the infeed area, the first infeed sensor constructed and arranged to detect individual product containers being conveyed through the entrance, a second infeed sensor positioned at an exit to the infeed area, and a gate positioned adjacent to the exit, the gate having a default closed position and is actuatable to an open position, in the closed position the gate prevents product containers from being conveyed out of the infeed area, the gate being actuated from the closed position to the open position only when the first infeed sensor detects a predetermined number of product containers having passed through the entrance;
a pattern conveyor, the pattern conveyor having a second movable conveyor positioned down-stream from the infeed area and off-set 90 degrees from the first moveable conveyor; and
a cross-pusher assembly, the cross-pusher assembly positioned downstream of the infeed area, the cross-pusher assembly having a cross-pusher arm, the cross-pusher arm being actuatable between a first position and a second position, the first position and the second position defining a stroke distance therebetween,
the cross-pusher arm comprises a first portion that extends parallel to the first moveable conveyor, and an elbow portion that extends in a curve from the first portion, the cross-pusher arm also comprising an insert, the insert defining a face, in the first position the face being configured to contact each of the predetermined number of product containers advanced through the gate, a portion of the face extends over the elbow and further defines a stop surface, the stop surface positioned to receive a first of the predetermined number of product containers and prevents the predetermined number of product containers from being conveyed further by movement of the first moveable conveyor;
in the first position, the cross-pusher arm is positioned adjacent to a first side of the first moveable conveyor, in the second portion, the cross-pusher arm is positioned on a second side of the first moveable conveyor opposite the first side and the cross-pusher arm is also positioned over a staging area of the pattern conveyor;
when the cross-pusher arm is actuated from the first position to the second position, the pattern conveyor advances the same distance as the stroke distance.

US Pat. No. 10,689,206

TRANSPORT DEVICE FOR TRANSPORTING PUCKS

KRONES AG, Neutraubling ...

1. A transport device for transporting pucks which are configured to transport containers, comprising:a puck transport section for transporting pucks to a container treatment machine and away from the container treatment machine; and
a puck buffer from which pucks can be coupled into the puck transport section and to which pucks decoupled from the puck transport section can be fed,
the transport device configured such that the pucks are coupled from the puck buffer into the puck transport section before an infeed of the container treatment machine and are decoupled from the puck transport section and fed to the puck buffer after an outfeed of the container treatment machine.

US Pat. No. 10,689,205

PACKAGE ACCUMULATING DEVICE

ISHIDA CO., LTD., Kyoto ...

1. A package accumulating device that conveys plural bag packages to a predetermined position while performing an accumulating operation that aligns the packages such that parts of each of the packages lie on top of parts of adjacent packages in a thickness direction and packs the packages in a cardboard box, the package accumulating device comprising:a first conveyor that performs the accumulating operation, the first conveyor having a first conveyance surface for accumulating the packages;
a second conveyor that receives and further conveys a group of the packages conveyed from the first conveyance surface of the first conveyor; and
a control unit that performs switching between
a first state in which a downstream end of the first conveyance surface of the first conveyor in a conveyance direction and an upstream end of a second conveyance surface of the second conveyor in the conveyance direction oppose each other when the second conveyor accepts the group of the packages from the first conveyance surface of the first conveyor and
a second state in which the second conveyance surface of the second conveyor is departed from the first conveyance surface of the first conveyor such that a position of the upstream end of the second conveyance surface of the second conveyor is lower than the position of the upstream end of the second conveyance surface of the second conveyor in the first state with respect to the downstream end of the first conveyance surface of the f first conveyor, wherein
the control unit lowers the upstream end of the second conveyance surface of the second conveyor after a last package of the group of the packages moves from the first conveyance surface of the first conveyor onto the second conveyance surface of the second conveyor, and
the control unit further causes the first conveyor
to perform the accumulating operation for a next group of the packages on the first conveyance surface of the first conveyor which has conveyed the group of the packages onto the second conveyor and
to perform the accumulating operation of the packages on the first conveyance surface of the first conveyor both in the first state and the second state.

US Pat. No. 10,689,204

ROLLERS WITH WEAR-INDICATING FEATURES AND BELT CONVEYOR INCORPORATING SAME

1. A belt conveyor, comprising rollers spaced apart in a conveying direction along a carryway run on which a conveyor belt is moved, each of the rollers comprises a hollow cylindrical body including an inner circumferential peripheral surface surrounding a volume of the hollow cylindrical body, an outer circumferential peripheral surface, in contact with the conveyor belt, and a thickness, from the outer circumferential peripheral surface to the inner circumferential peripheral surface, each extending between the opposed ends, and a weight within the volume connected to the body between the outer circumferential peripheral surface and the inner circumferential peripheral surface with a breakaway connection, wherein the breakaway connection breaks allowing the weight to drop into the volume and knock resoundingly against the inner circumferential peripheral surface, when thinning of the thickness of the body from wear of the outer circumferential peripheral surface reaches the breakaway connection.

US Pat. No. 10,689,203

WET CASE DETECTOR IN A CONVEYOR BELT

Laitram, L.L.C., Harahan...

1. A conveyor, comprising:a transparent conveyor belt body extending from a top conveying surface to an opposite bottom surface;
a liquid sensor adjacent the conveyor belt body for detecting moisture on the conveying surface, the liquid sensor comprising a light source for directing a light beam into the conveyor belt body towards the top conveying surface and a light receiver for detecting the light beam after it reflects off the top conveying surface.

US Pat. No. 10,689,202

APPARATUS FOR CONTROLLED TRANSPORT OF ARTICLES ALONG A PATH

The Procter and Gamble Co...

1. An apparatus for controlled transport of articles along a path comprising:a plurality of articles;
a track that forms a closed loop path for movers;
a plurality of movers that are configured to transport articles, said movers being movably mounted on the track for moving along said closed loop path, said movers comprising a driven member that is oriented to be contacted by at least one drive element at any position along the path;
a plurality of drive elements arranged along the track, said drive elements each comprising a surface that is oriented to contact the driven member of said movers, wherein said drive elements are configured to sequentially engage the driven member of said movers to provide controlled motion of said movers independently around said track, wherein the drive elements are each driven by a rotary motor; and
a programmable computer control system in communication with the rotary motors for controlling the motion of the rotary motors,
wherein each mover comprises a vacuum head which uses vacuum to selectively hold an article securely to the mover.

US Pat. No. 10,689,201

MATERIAL CONVEYOR SYSTEM BUCKET COMPRISING A WEAR BAND AND METHOD FOR MAKING THE SAME

BRAIME GROUP PLC, Leeds ...

1. A material conveyor system container comprising:an elevator bucket having a back wall, opposed sidewalls, a bottom wall curving upward into a front wall spaced from the back wall, and a wear band;
the front wall being joined to the bottom wall to form an open top;
the front wall and bottom wall portions being joined to the opposed sidewalls by arcuate corner parts,
the wear band extending entirely across a top portion of the front wall and integral corner parts to protect the top portion of the front wall and integral corner parts from a flow of material wearing the elevator bucket; and
the wear band extending across a forward portion of a top portion of the opposed sidewalls, wherein the wear band is made of a highly abrasion resistant material and a remainder of the elevator bucket is made of a polyethylene material.

US Pat. No. 10,689,200

SORTING SYSTEM THAT TRANSFERS PAYLOADS FROM A CONVEYOR SYSTEM ONTO MOBILE DRIVE UNITS WITHOUT THE CONVEYOR SYSTEM KNOWING DESTINATIONS OF THE MOBILE DRIVE UNITS

Amazon Technologies, Inc....

1. A sortation system configured to sort payloads at a facility, the sortation system comprising:a mobile drive unit system comprising a drive unit controller and a plurality of mobile drive units configured to carry the payloads to different local destinations at the facility; and
a conveyor system comprising:
a first conveyor end and a second conveyor end that are offset from one another;
a conveyor surface configured to carry payloads along a direction that extends from the first conveyor end to the second conveyor end, and transfer the payloads to the mobile drive units at the second conveyor end;
a conveyor controller configured to control operation of the conveyor surface; and
a scanner configured to scan barcodes on the payloads to identify a payload identifier for each payload, wherein the payload identifiers are masked such that information about the local destinations such that the local destinations are unknown to the conveyor system,
wherein the conveyor controller is configured to communicate the payload identifiers to the drive unit controller, and the drive unit controller is configured to determine the local destinations from the payload identifiers by unmasking the payload identifiers, and communicate the local destinations to respective mobile drive units.

US Pat. No. 10,689,199

BAR CONVEYOR

1. A continuous bar conveyor adapted for use in a food industry, comprising:a plurality of bars, having ends constrained by chains having links configured to be engaged by motorized toothed wheels, so as to move the continuous bar conveyor along fixed guides; and
a plurality of spirals wrapping said bars in pairs, said links of said chains and said spirals being configured to limit a maximum distance between adjacent bars of the plurality of bars, but also to allow a reciprocal movement of the adjacent bars together,
wherein, between adjacent successions of at least two bars of the plurality of bars, wrapped by one of the plurality of spirals, there is disposed at least one bar of the plurality of bars, which is not wrapped by the spirals, and to which a sheet of plastic material is constrained, having resistance to an operating temperature of said conveyor and a smooth, non-stick surface, said sheet resting on an upper surface defined by said spirals and having a dimension in an advancing direction of the continuous bar conveyor smaller than a distance between successive bars of the at least one bar not wrapped by the spirals.

US Pat. No. 10,689,198

CONVEYOR APPARATUS

Furukawa Industrial Machi...

1. A conveyor apparatus comprising:a plurality of outgoing path side guide pulleys and a plurality of returning path side guide pulleys disposed along a helical conveyance path extending in a vertical direction and arranged at positions where inflection points of the helical conveyance path are formed such that the plurality of outgoing path side guide pulleys and the plurality of returning path side guide pulleys form the inflection points;
an endless conveyor belt wound around the plurality of outgoing path side guide pulleys in turn along the helical conveyance path in a bent state where the endless conveyor belt is folded in two in a width direction in such a manner that an upper edge portion of the endless conveyor belt is supported by the plurality of outgoing path side guide pulleys, the endless conveyor belt being wound around the plurality of returning path side guide pulleys in turn along the helical conveyance path in the bent state where the endless conveyor belt is folded in two in the width direction in such a manner that the upper edge portion is supported by the plurality of returning path side guide pulleys, and further, the endless conveyor belt being folded back at turning positions of an upper side and a lower side of the helical conveyance path and being in an expanded state where the endless conveyor belt is expanded in the width direction in a vicinity of each of the turning positions;
a pair of an upper side turning pulley and a lower side turning pulley configured to support and guide the endless conveyor belt to stretch at the respective turning positions; and
drive motors configured to drive pulleys among some or all of the plurality of outgoing path side guide pulleys, the plurality of returning path side guide pulleys, the upper side turning pulley, and the lower side turning pulley,
wherein the drive motors are provided in a dispersed manner at some positions among positions of the plurality of outgoing path side guide pulleys forming the inflection points, the plurality of returning path side guide pulleys forming the inflection points, the upper side turning pulley, and the lower side turning pulley,
on each of outer circumference surfaces of the plurality of outgoing path side guide pulleys and the plurality of returning path side guide pulleys, a first recessed portion and a second recessed portion each having a trapezoidal cross sectional shape are formed endlessly in a circumferential direction, the second recessed portion being formed on the lower side of the first recessed portion, one end portion on one side of the endless conveyor belt being formed into a trapezoidal cross sectional shape and fitted into the first recessed portion, and another end portion of another side of the endless conveyor belt being formed into a trapezoidal cross sectional shape and fitted into the second recessed portion,
the position where the inflection points are formed are set at corner portions of a support frame having an axis extending in a vertical direction and having a polygonal shape when viewed from above,
the upper edge portion of the endless conveyor belt in the bent state where the endless conveyor belt is folded in two in the width direction include: the one end portion of the endless conveyor belt disposed at an upper side; and the another end portion of the endless conveyor belt having an inclined lower surface, the another end portion being vertically arranged at a lower side with respect to the one end portion, and is supported by a supported by a plurality of conveyor belt support mechanisms.

US Pat. No. 10,689,197

CONVEYOR APPARATUS, SYSTEMS AND METHODS

Superior Industries, Inc....

1. A conveyor guard removably supportable on a belt conveyor idler assembly having a base frame, an end stand supported by and extending from the base frame and at least one idler roll supported on the end stand, the conveyor guard comprising:a longitudinally extending rail;
a bracket configured to support said rail, said bracket comprising:
an arm;
a rail support positioned at a first end of said arm; and
an arm mount positioned at a second end of said arm, said arm mount configured to be removably secured to the end stand, wherein said first and second ends of said arm are spaced apart such that said arm is configured to extend generally upwardly and outwardly away from the end stand such that said rail is positioned above said arm mount when said arm mount is secured to the end stand.

US Pat. No. 10,689,196

PROCESSING MATERIALS

XYLECO, INC., Wakefield,...

1. A method of conveying a material, the method comprising:conveying a biomass material having a bulk density of less than 0.7 g/cm3 through a field of accelerated electrons, the electrons impinging upon a treatment zone of a vibratory conveyor, wherein the treatment zone includes a beam dump in thermal communication with the treatment zone,
wherein the biomass material is treated with electron bombardment having energies of 0.5-10 MeV through the field of accelerated electrons.

US Pat. No. 10,689,195

SYSTEM OF BUFFER STORAGE AND SEQUENCING OF LOADS UPSTREAM TO AT LEAST ONE PREPARING STATION

SAVOYE, Dijon (FR)

1. A system of buffer storage and sequencing of loads configured to receive non-sequenced loads coming from at least one external unit through at least one inbound forward conveyor included in said system and to provide at least one predetermined sequence of loads, comprising loads in a predetermined sequential order, to at least one preparing station, through at least one outbound forward conveyor included in said system, wherein said system comprises:a reciprocating lift comprising only one nacelle comprising K levels each enabling the transportation of at least one load, with K?2;
at least one buffer storage unit comprising a plurality of buffer locations distributed over a plurality of levels and each configured to temporarily receive at least one load coming from the only one nacelle of the reciprocating lift; and
a managing unit configured to organize:
first movements of loads from said at least one inbound forward conveyor to said at least one buffer storage unit, through the only one nacelle of the reciprocating lift; and;
second movements of loads from said at least one buffer storage unit to said at least one outbound forward conveyor, through the only one nacelle of the reciprocating lift, under a constraint of delivery, on said at least one outbound forward conveyor, of said at least one predetermined sequence of loads,
wherein each of the K levels of the only one nacelle of the reciprocating lift is able to come next to each of the levels of the at least one buffer storage unit for a transfer of at least one load,
wherein said first movements of loads comprise, for a given load, a movement of said given load from one of the K levels of the only one nacelle of the reciprocating lift directly to one of the buffer locations of said at least one buffer storage unit,
and wherein said second movements of loads comprise, for a given load, a movement of said given load from one of the buffer locations of said at least one buffer storage unit directly to one of the K levels of the only one nacelle of the reciprocating lift.

US Pat. No. 10,689,194

MOBILE ROBOT LOADER-UNLOADER SYSTEM AND METHOD

HDS Mercury, Inc., Palo ...

1. A system for moving payloads comprising:at least one mobile robot; wherein each mobile robot comprises a payload bearing platform, and a payload release latch; and
at least one stack exchanger having a set of alignment elements, a payload transfer ramp, and a latch engagement bar;
wherein each said mobile robot passes through the stack exchanger and picks up a payload or drops off a payload;
wherein said stack exchanger alignment elements direct each mobile robot payload bearing platform to reversibly engage the payload transfer ramp, and the stack exchanger latch engagement bar releases each mobile robot's payload release latch during mobile robot traversal of said stack exchanger;
wherein each stack exchanger further comprises a payload exchange area comprising rolling elements wherein the latch engagement bar releases the mobile robot release latch so that the passing mobile robot payload is released in the payload exchange area.

US Pat. No. 10,689,193

GOODS-TO-MAN WAREHOUSING COMPRISING MULTILEVEL RACKING, MOBILE STORAGE UNITS, STORAGE UNIT TRANSPORTERS, AND PICK-PLACE VEHICLE

Crown Equipment Corporati...

1. A goods-to-man warehousing system comprising:a multilevel racking system;
a plurality of multilevel mobile storage units structurally configured to permit a storage unit transporter to travel beneath the mobile storage units when the mobile storage units are standing on a warehouse floor;
a storage unit transporter configured to travel under the multilevel mobile storage units;
a pick-place vehicle; and
a mobile storage unit transfer node accessible by the storage unit transporter and the pick-place vehicle, wherein
the multilevel racking system comprises a vertically and horizontally distributed array of storage bays and a plurality of racking system aisles,
the storage unit transporter and the pick-place vehicle are configured to travel in the racking system aisles,
one or more of the multilevel mobile storage units are positioned in respective ones of the storage bays of the multilevel racking system,
the pick-place vehicle comprises pick-place hardware that enables the pick-place vehicle to transfer multilevel mobile storage units between a plurality of different, vertically displaced storage bays of the multilevel racking system and the mobile storage unit transfer node of the goods-to-man warehousing system, and
the storage unit transporter comprises storage unit engagement hardware that enables the storage unit transporter to transport multilevel mobile storage units to and from the mobile storage unit transfer node of the goods-to-man warehousing system.

US Pat. No. 10,689,190

TRASH CAN CLIP SYSTEM AND METHOD

Billie Toba Hale, Jr., H...

1. A trash can clip system comprising:a lip; and
one or more clips;
wherein:
said trash can clip system is positionable proximate to an opening of a trash can;
said lip comprises an elongated component; and
said lip comprises one or more at least partially void sections there along; and
wherein, at least one said clip:
comprises a substantially u-shaped portion that, in an engaged position, accommodates at least a portion of said lip there within;
is positionable along said lip, in a disengaged position, within one said at least partially void lip section;
is outwardly rotatable when positioned in said disengaged position; and
is slidingly reversibly movable along said lip from said engaged position to said disengaged position.

US Pat. No. 10,689,189

EXTERNAL FLOATING ROOF TANK SHELL EXTENSION

PHILLIPS 66 COMPANY, Hou...

1. A process for expanding the capacity of a floating roof cylindrical tank for storing hydrocarbons comprising:providing a cylindrical tank with a generally circular base having a periphery extending fully around the circular base and generally cylindrical peripheral wall extending vertically upward to a top edge and a floating roof with two spaced apart seals arranged for sealing contact against the generally cylindrical peripheral wall;
providing a plurality of brackets up to the top of the floating roof where the brackets include pre-drilled holes for attaching extension panels;
providing a plurality of extension panels that are each thinner and lighter weight than the generally cylindrical peripheral wall up to the top of the floating roof where the extension panels include pre-drilled holes to attach to the brackets and to attach each panel to others of the plurality of panels;
providing a sealant between each bracket and the generally cylindrical peripheral wall and attaching each bracket to the generally cylindrical wall end to end so as to create a sealed connection between the brackets and the generally peripheral wall and to provide a structure for which the extension panels may be attached to the generally cylindrical peripheral wall;
providing a sealant between each of the panels and the bracket and attaching each of the panels to the bracket and to one another in an overlapping arrangement where the panels overlap at least part of the bracket and where at least part of each panel overlaps with other panels with sealant between where they overlap such that when the panels are attached to the brackets they form a generally cylindrical wall extension extending upwardly from the generally cylindrical wall such that the upper of the two seals on the floating roof may move vertically with the floating roof and maintain a sealed vapor space as the seal passes above the top edge of the generally cylindrical peripheral wall and into contact with the panel extensions sealed together and to the generally cylindrical peripheral wall.

US Pat. No. 10,689,188

CONDIMENT PACKET HOLDER

BOSCAL, LLC, West Hollyw...

1. A condiment packet holder, comprising:a. a rectangular base side having a first edge, a second edge, a third edge, and a fourth edge, wherein the first edge is opposite to the second edge, the third edge is adjacent and perpendicular to the first and second edges, and the fourth edge is opposite to the third edge and adjacent and perpendicular to the first and second edges;
b. a first sidewall adjacent to the first edge of the rectangular base side and a second sidewall adjacent to the second edge of the rectangular base side;
c. a third sidewall adjacent to the third edge of the rectangular base side and a fourth sidewall adjacent to the fourth edge of the rectangular base side;
d. a rectangular top side having a first edge, a second edge, a third edge, and a fourth edge, wherein the first, second, third, and fourth edges of the top side are adjacent to the first, second, third, and fourth sidewalls, respectively;
e. a cavity, which is defined by one or more internal sidewalls, wherein the top side has an opening in fluid communication with the cavity sized to hold one single-serving condiment packet; and
f. wherein the rectangular base side has a width of approximately 15 mm to approximately 50 mm and a length of approximately 15 mm to approximately 85 mm, and the holder has a height of approximately 15 mm to approximately 60 mm, and
g. wherein the cavity has a width of approximately 5 mm to approximately 15 mm, a length of approximately at least 15 mm, and the cavity has a depth of approximately 15 mm to approximately 60 mm.

US Pat. No. 10,689,187

ROTOR SECURING JIG AND ROTOR STORAGE UNIT

MITSUBISHI HEAVY INDUSTRI...

1. A rotor securing jig comprising:a first member that is able to be secured to a first end portion of a rotor, which is an end the portion of the rotor on a first side in an axial direction;
a second member that is provided relatively movable in the axial direction with respect to the first member; and
a third member that is configured to be secured to a container, and has a first abutting surface facing a second side in the axial direction, which is an opposite side to the first side, and configured to abut the first member, and a second abutting surface facing the first side and configured to abut the second member,
wherein the first member is separate from the rotor,
the first member has a cylindrical portion that is configured to allow the first end portion of the rotor to be inserted therein from the second side,
the second member has an insertion portion that is configured to be inserted into the cylindrical portion from the first side and a flange portion that protrudes outward from an end portion of the insertion portion on the first side in a radial direction,
the first member and the second member are relatively movable in a state where the insertion portion is inserted in an inner circumferential surface of the cylindrical portion, and
the first abutting surface of the third member comes into contact with the cylindrical portion, and the second abutting surface comes into contact with the flange portion.

US Pat. No. 10,689,186

PACK FOR CIGARETTES

1. A pack for rod-shaped objects, having a box part (11) which is delimited by at least one front wall (15), one rear wall (12), side walls (16, 17) and one bottom wall (14), wherein the box part (11) serves for receiving at least one cuboid group of rod-shaped objects wrapped in an inner blank (30) and wherein the pack (10) comprises predefined dimensions with regard to the width, the depth and the height, and at least one dimension of the at least one group of rod-shaped objects is smaller than a corresponding dimension of the interior of the box part (11) so that the at least one group of rod-shaped objects does not fill out the interior of the box part (11) with reference to the at least one dimension of the at least one group of rod-shaped objects that is smaller than a corresponding dimension of the interior of the box part (11), and wherein a collar (26) is arranged in the box part (11), consisting of at least one collar front wall (27), which abuts against the front wall (15) of the box part (11), and collar side walls (28) which are arranged adjacent to side walls (16, 17) of the box part (11), the box part (11) comprising:a) at least one bottom flap (32) of the collar (26), which extends directed transversely to the at least one collar front wall (27) as a bottom-side support of the at least one group of rod-shaped objects, the at least one bottom flap (32) being arranged so that the collar (26) serves for compensating for a shallower height of the group of rod-shaped objects, the at least one bottom flap (32) being connected in an articulated manner to the at least one collar front wall (27) at a lower edge of the at least one collar front wall (27), and the at least one bottom flap (32) being held on the collar side walls (28) in a position directed transversely to the at least one collar front wall (27) by bearing projections (51) impressed in the material of the collar side walls (28) of the at least one bottom flap (32) opposite the side edges;
b) the or each group of rod-shaped objects further comprises a shallower depth than the interior of the box part (11), and wherein the smaller dimension of the group of rod-shaped objects is compensated for by a filling piece (37) produced by folding a separate blank which is arranged between the or each group of rod-shaped objects and a rear wall (12) of the box part (11); and
c) the filling piece (37) serves as a bearing element for the at least one bottom flap (32) of the collar (26) and comprises an opening (38) for a bearing arrangement of the at least one bottom flap (32), wherein a lower edge of the opening (38) serves as a support edge and further bearing element for the at least one bottom flap (32).

US Pat. No. 10,689,185

DIFFUSER ASSEMBLY FOR AEROSOL

COMPAGNIE GENERALE DES ET...

1. An aerosol product diffuser assembly for a pressurized bottle comprising:a diffuser block comprising an annular casing inside which a cam actuator is mounted axially mobile between a storage position of the aerosol and a diffusion position of the aerosol; and
a control lever provided with a planar body making it possible to control the diffusion of the aerosol liquid,
wherein the cam actuator comprises:
(i) a cam follower plate, axially mobile and guided by guide studs fixed to the annular casing and engaging with corresponding notches in the cam follower plate;
(ii) an aerosol bottle nozzle housing, arranged on the cam follower plate and suitable for receiving a nozzle of an aerosol bottle;
(iii) a duct and a diffuser tip, connected to the nozzle housing and enabling the liquid to diffuse to a discharge point of the aerosol liquid,
wherein the control lever is pivotably mounted on the annular casing,
wherein the cam actuator is able to be pushed axially toward the aerosol bottle by at least one pivoting cam, mounted on the planar body of the control lever,
wherein the cam actuator is pushed axially away from the aerosol bottle by at least one elastic fastening tab elastically connecting the cam actuator to the annular casing, and
wherein the cam actuator is formed integrally with the annular casing, thus forming a one-piece diffuser block.

US Pat. No. 10,689,184

WRIST-MOUNTED PRESSURIZED FLUID SHOOTER

1. A fluid-shooting toy, comprising:an outer housing;
a check valve vessel;
a lever attached to a geared-triggered system;
a fluid-filled canister;
a pressurized air housing;
wherein the check valve vessel, which is connected to the fluid-filled canister, comprises:
a small check valve, normally in the closed position;
a tee fitting attached to the small check valve on an inlet side;
a rubber bellows attached to the small check valve on an outlet side;
and a spray nozzle attached to the rubber bellows; wherein the spray nozzle, cheek valve vessel, and lever are connected via the geared-triggered system.

US Pat. No. 10,689,183

CONTAINER OF FLUID SUBSTANCES WITH HERMETIC SEALING SYSTEM AND METHOD OF USE

LUMSON S.P.A., Capergnan...

1. A container for a fluid substance, comprisinga body having a neck delimiting an opening for access to a cavity of the body itself, and
a containment element having at least one deformable side wall located inside the cavity and intended to contain the fluid substance,
the interior of the containment element being associated in a sealed manner to a collar having at least one resting surface on the body and a tubular member extending from its bottom,
the tubular member defining a first passage of the fluid substance during use, within the collar an insert being located, formed by a first and a second part mutually connected by a first breakable portion,
wherein inside the insert is located a shutter formed by a first section and a second section mutually connected by a second breakable portion,
the second section comprising a surface configured to cooperate with the tubular member when the second section is fitted on the tubular member and a breakable wall through which, when the breakable wall is broken, access within the containment element is permitted.

US Pat. No. 10,689,182

MULTI-COMPARTMENT DISPOSABLE POUCH

1. A multi-compartment pouch having upper and lower ends, the pouch comprising:two outer walls and two inner divider walls, upper and lower ends of the outer walls being sealed to one another through respective upper and lower ends of the inner divider walls;
the upper end of the pouch comprising an upper opening feature extending across the upper end of the pouch, and the lower end of the pouch comprising a lower opening feature extending across the lower end of the pouch;
the inner divider walls defining an inner compartment therebetween with a lower openable end at the lower end of the pouch, and the inner divider walls and their respective outer walls defining outer compartments therebetween with upper openable ends at the upper end of the pouch;
the lower ends of the inner divider walls sealed to one another over a first shorter end seal region and further sealed over a first longer seal interface region to respective inside faces of the outer wall lower ends;
the upper ends of the inner divider walls sealed over a second shorter end seal region to respective inside faces of the outer wall upper ends; and,
the inner divider wall upper ends further sealed to one another over a second longer seal interface region of greater length than the second shorter end seal region; wherein,
the upper opening feature at the upper end of the pouch is located interiorly of the second shorter end seal region and exteriorly of a junction portion of the second longer seal interface region across the upper openable ends of the outer compartments, and the lower opening feature at the lower end of the pouch is located exteriorly of a junction portion of the first longer seal interface region and interiorly of the first shorter end seal region across the lower openable end of the inner compartment.

US Pat. No. 10,689,181

MIXING CONTAINER, MIXING CONTAINER KIT, METHOD OF USING MIXING CONTAINER OR MIXING CONTAINER KIT, AND ASSISTIVE DEVICE OF MIXING CONTAINER

KABUSHIKI KAISHA SHOFU, ...

1. A mixing container for mixing multiple materials, the mixing container comprising:a container body including a storage part configured to store the multiple materials, the storage part having at least one partition wall formed such that a portion of an inner wall surface forming the storage part is raised toward a storage space, the at least one partition wall forming multiple storage chambers capable of separately storing the multiple materials in the storage part;
a lid member attached to the container body to seal a circumferential edge of the storage part and an upper edge of the at least one partition wall partitioning the multiple storage chambers from each other such that the multiple storage chambers are separately sealed; and
a handle part having a coupling part coupled to the at least one partition wall and an operating part configured to be operated by a user,
wherein:
the operating part is made up of a pair of members extending from the coupling part to respective sides opposite to each other;
the handle part includes a receiving part configured to receive at least a portion of the container body coupled to the coupling part;
the receiving part is configured such that a circumferential edge of the receiving part and the container body are flush with each other when the at least the portion of the container body is received in the receiving part;
the lid member includes a tab;
the tab is disposed along the handle part;
the mixing container is configured such that, as the operating part relatively moves in a direction from the lid member toward the container body with respect to the container body, the at least one partition wall moves together with the coupling part in the direction from the lid member toward the container body;
the at least one partition wall is configured to be deformable into a concave part recessed in a movement direction of the at least one partition wall through movement in the direction from the lid member toward the container body with the circumferential edge of the storage part sealed to the lid member; and
when the at least one partition wall is deformed into the concave part, the multiple storage chambers formed by the at least one partition wall are deformed into one storage chamber.

US Pat. No. 10,689,180

CONNECTING AND CONTAINER SYSTEM

BOEHRINGER INGELHEIM VETM...

1. A container system, comprising: at least one container having a removal opening for withdrawing content from the container, and a connecting arrangement on a side remote from the removal opening, the connecting arrangement being irreversibly openable for providing a fluidic connection between the container and another container, and a removable cover having a receptacle for covering the connecting arrangement, the cover also being formed with a holding device for a region of the container forming the removal opening, so that the cover is usable as a support foot for the container by removing the cover from covering the connecting arrangement and using the holding device for holding the container in the region forming the removal opening.

US Pat. No. 10,689,179

CONTAINER FOR TRANSPORT AND STORAGE OF FOOD PRODUCTS

ZUME, INC., Mountain Vie...

1. A system of stacked food containers comprising:a first food container comprising a base, the base including:
an upwardly facing food receiving portion to receive a food product, wherein the upwardly facing food receiving portion includes a perimeter and a substantially planar surface; and
at least a portion of a rim is disposed at the perimeter of the upwardly facing food receiving portion, wherein the at least a portion of a rim is raised relatively above the upwardly facing food receiving portion;
wherein the upwardly facing food receiving portion further includes:
a plurality of sector portions, including a first and second sector portion, angularly arrayed with respect to one another, each of the sector portions having an upward facing surface and a plurality of raised projections extending upwardly from the upward facing surface, and the first sector portion having a first sector well and the second sector portion having a second sector well, the second sector well being separate and distinct from the first sector well, wherein the first sector well and the second sector well each extend downwardly from a planar surface of the food receiving portion;
a plurality of channels that delineate respective pairs of the sector portions from one another, each channel of the plurality of channels extending relatively below the upward facing surface of the sector portions; and
a central well about which the sector portions are angularly arrayed, the central well having a perimeter and extending relatively below the upward facing surface of the sector portions, and each channel of the plurality of channels extending to the perimeter of the central well such that each channel is spaced apart from the other channels around the perimeter of the well; and
a second food container comprising a cover, the cover including:
a substantially downward facing interior surface and a substantially upward facing exterior surface, wherein the cover is sized and shaped to provide an interior chamber which protects the food product; and
a central dome portion having a first dome recess sized and shaped to receive at least a portion of the first sector well and a second dome recess sized and shaped to receive at least a portion of the second sector well, wherein the first sector well of the base is engaged with at least a portion of the first dome recess sized and the second sector well of the base is engaged with at least a portion of the second dome recess; and
an air space formed at least in part by the engagement of the first sector well of the base with at least a portion of the first dome recess and the engagement of the second sector well of the base with at least a portion of the second dome recess, wherein the air space is disposed between the base of the first food container and the substantially upward facing exterior surface of the cover of the second food container.

US Pat. No. 10,689,178

PACKING CONTAINER HAVING EXCELLENT SLIPPING PROPERTY FOR THE CONTENT

TOYO SEIKAN GROUP HOLDING...

1. A packing container which is a directly blow-formed bottle filled with a water-containing content, wherein:said bottle has a multilayer structure inclusive of an inner surface layer that comes in contact with said content, at least part of the surface of said inner surface layer is a liquid- permeable surface formed of a particulate material layer, and said liquid-permeable surface has a mean square surface roughness RMS represented by the following formula (1) ,

wherein n is a number of data points,
Z(i) is a value of Z at each data point, and
Zave is an average value of all Z values in a surface shape profile obtained by scanning a range of 10 ?m×10 ?m by using an atomic force microscope, that lies in a range of 90 nm to 240 nm;
said liquid-permeable surface holds an oily liquid different from said content in an amount of 1.0 to 50 g/m2, and wherein:
(a) said particulate material layer forming said liquid- permeable surface, is formed with an olefin resin layer as the underlying layer;
(b) said particulate material layer contains polyolefin particles and fine particles of an inorganic oxide selected from titanium oxide, alumina and silica, the fine particles of said inorganic oxide having an average primary particle size in a range of not larger than 200 nm; and
(c) an ethylene-vinyl alcohol copolymer layer is provided as an intermediate layer being located under said olefin type resin layer.

US Pat. No. 10,689,177

RESEALABLE PACKAGES FOR SNACK PRODUCTS

Frito-Lay North America, ...

1. A reclosable package, comprising:a flexible package body comprising a flexible material rolled into a rectilinear tubular shape having openings at top and bottom ends, the flexible package body having a front surface and a back surface opposing the front surface, the front and back surfaces separated by opposing sides and opposing top and bottom end seals closing the openings at the top and bottom ends;
a peelable flap located on the front surface and connected to the front surface at a portion of the perimeter of the flap, the flap entirely covering an opening through the front surface of the package sized for accessing product held within the package;
a pull tab connected to the flap;
a rigid sidewall adhered externally on each of the opposing sides, each rigid sidewall providing opposing inward concave curvatures to the opposing sides to provide an hourglass shape to the package from the top end seal to the bottom end seal, and having a rigidity sufficient to provide structural support to the opposing sides to maintain separation of the front and back surfaces such that they maintain a thickness for the package, thereby forming a space therebetween for holding the product within the recloseable package; and
an aperture formed through a portion of the top end seal.

US Pat. No. 10,689,176

RE-SEAL LABEL AND CONTAINER WITH RE-SEAL LABEL

Altria Client Services LL...

1. A box in a box re-sealable container comprising:an outer box including a hinged lid;
an inner box inside the outer box, the inner box including an access opening which is accessible when the hinged lid of the outer box is opened; and
a re-sealable label including a first zone of permanent adhesive at an upper portion of the re-sealable label on an underside of the re-sealable label which attaches the re-sealable label at least to a back wall of the inner box, a line of perforations defining a connecting tab at a lower portion of the re-sealable label, each of the perforations of the line of perforations including a rectilinear portion and a non-rectilinear portion, a second zone of permanent adhesive at an outer side of the connecting tab that attaches the connecting tab to an inner surface of the hinged lid of the outer box, and a zone of re-sealable adhesive on the underside of the re-sealable label that releasably attaches to a top wall and a front wall of the inner box such that a liner on the underside of the re-sealable label covers the access opening when the hinged lid is in a closed position and uncovers the access opening when the hinged lid is in an open position.

US Pat. No. 10,689,175

DYNAMIC PACKAGING

Apple Inc., Cupertino, C...

1. A product with packaging, comprising:a product;
a tray, comprising:
a movable anchor comprising folded paper;
a paper spring coupled to the movable anchor; and
a fixed anchor comprising folded paper and fixed to the tray,
wherein the movable anchor and fixed anchor together retain the product in position relative to the packaging under force applied by the paper spring, and
wherein in response to a force moving the movable anchor relative to the product and against a biasing force of the paper spring, the product is released and removable from the packaging.

US Pat. No. 10,689,174

METHOD FOR PRODUCING PACKING SHEET WITH IMPROVED INSULATION AND STORAGE PROPERTIES

1. A method for producing a packing sheet with improved insulation and storage properties, the method comprising:a) producing a formed film on which convex ridges are formed at a regular interval in a direction from a front side to a rear side thereof;
b) sealing the ridges by attaching a lower film to a lower side of the formed film, the lower film being configured such that a first end thereof is extended in a first side direction thereof longer than a first end of the formed film;
c) attaching an upper film onto the sealed ridges of the formed film, the upper film being configured such that a first end thereof is extended in a first side direction thereof longer than the first end of the formed film;
d) opening a portion of each of the sealed ridges of the formed film
e) allowing the formed film, the lower film, and the upper film to pass between a pair of rotary rollers so as to remove a fluid in the ridges having the opened portions while compressing the formed film, the lower film, and the upper film; and
f) winding on an outer surface of a winding roller the lower film, the formed film, and the upper film that are in a state in which second ends thereof are sealed, or the lower film, the formed film, and the upper film that are in a state in which the second ends thereof are not sealed.

US Pat. No. 10,689,173

ELASTOMER LINED SELF-LOCKING TIE

LOCK RIGHT, LLC, West Va...

1. A self-locking tie, comprising:an elongated strap including a head end and a tapered end, the tapered end disposed opposite the head end on the elongated strap, the tapered end comprising a first surface disposed opposite a second surface;
at least one cavity disposed in at least one of the first surface and the second surface;
an elastomer segment disposed within the at least one cavity and extending beyond at least one of the first surface and the second surface;
a locking head extending from the head end of the elongated strap, the locking head comprising an orifice shaped to receive the tapered end of the elongated strap and the elastomer segment.

US Pat. No. 10,689,172

PEEL-AWAY SHAKER CAN AND CAN MEMBRANE

SONOCO DEVELOPMENT, INC.,...

1. A multi-layered peel-away dispensing laminate comprising:a metalized polymeric layer, wherein the metalized polymeric layer has an upper surface and a lower surface and the lower surface is adapted to be adhered to a container body over an open end of the container;
a pressure sensitive adhesive layer adjacent the entire upper surface of the polymeric layer; and
a peelable film layer having an upper surface and a lower surface wherein the lower surface of the peelable film layer is adhered to the upper surface of the polymeric layer by the pressure sensitive adhesive, and wherein the laminate is undercut through only the polymeric layer in the form of at least one opening, such that when the peelable film layer is peeled away when the container is opened, dispensing openings are formed in the polymeric layer; and
wherein when the peelable film layer is peeled away, the portion of the polymeric layer inside the at least one undercut opening remains adhered to the peelable film layer;
a tab disposed in the peelable film layer; and
multiple undercut scoremarks in the metalized polymeric layer, located circumferentially adjacent the tab, and disposed such that the scoremarks will be adjacent the seal position of the laminate on the open end of the container, wherein the multiple undercut scoremarks comprise parallel lines.

US Pat. No. 10,689,171

CONTAINER WITH LID FOR FACILITATING MIXING OF MATERIALS USED FOR CONSTRUCTION AND MAINTENANCE

1. A material mixing device, comprising:a container, a lid, a mixer including a power drill and a mixing paddle rotated by said power drill, said lid including lid sidewalls that extend upwardly and away from said lid, said lid sidewalls extending about a perimeter of said lid, said lid further including a plurality of openings, said plurality of opening being longitudinal perforations extending from a center of said lid to said lid sidewalls, said longitudinal perforations further extending beneath of said lid.

US Pat. No. 10,689,170

TANK CLOSURE APPARATUS

1. A tank closure apparatus comprising:a) a tank body having a tank outer wall, tank surrounding a tank interior, the body having a top;
b) the top having a first, larger diameter opening;
c) a lid that forms a closure to the larger diameter opening the lid having a central, smaller diameter opening;
d) a threaded outlet fitting attached to the lid at the smaller diameter opening, said outlet fitting having an upper portion, a lower portion attached to the lid and threads that extend from the upper portion downwardly to a lower most thread;
e) the lid and the tank body top each having an annular rib, said ribs being aligned and abutting to define a closed position of the lid upon the larger diameter opening;
f) a clamp that holds the annular ribs together;
g) a closure cap that can be removably attached to the outlet fitting, a tether provided on the lid that goes between the closure cap and the lid;
h) a shroud that provides a central shroud opening that is sized and shaped to fit over the outlet fitting so that at least a part of the outlet fitting penetrates the shroud opening, said shroud including a disk part and an annular skirt, the shroud having a slot that extends laterally away from said central shroud opening, and wherein said tether occupies said slot;
i) wherein the shroud is connected to and protectively covers the lid, annular ribs and clamp in an operating position that is perfected by placing the shroud over the lid, wherein at least a part of the outlet fitting extends through the lid opening and forms a removable connection with the closure cap; and
j) wherein the closure cap has a diameter that is greater than the diameter of the shroud opening.

US Pat. No. 10,689,169

CHILD-RESISTANT FLIP-TOP CLOSURE AND LOCKING SYSTEM FOR A CONTAINER

PACKAGING CONCEPTS ASSOCI...

1. A closure system for a dispensing container, comprising:a body member comprising:
an outer wall comprising a first vertical edge formed in the outer wall and comprising a horizontal slot formed therethrough, and a recess formed in the outer wall adjacent to the first vertical edge; and
a hollow passageway formed through the body member; and
a rotating closure member comprising:
a lower section configured to be secured to the body member and comprising a central opening and a cantilevered tab comprising a locking edge, which in a locked configuration, abuts a second vertical edge defined by the recess of the body member configured to prevent rotation of the rotating locking member;
an upper section configured to cover the central opening and the hollow passageway in a closed configuration and comprising a protruding tab; and
a hinge connecting the lower section and the upper section in a manner that enables opening the rotating closure member to an open configuration;
wherein the protruding tab is at least partly received in the slot of the body member in the locked configuration and the slot prevents vertical movement of the protruding tab and opening of the rotating closure member;
wherein the cantilevered tab is configured to be flexed inwardly to dispose the locking edge within the outer wall of the body member and out of abutment with the second vertical edge to enable the rotation of the rotating closure member in a first axial direction to an unlocked configuration; and
wherein in the unlocked configuration, the protruding tab is disposed over the recess and out of the slot of the body member to enable the vertical movement of the protruding tab to open the rotating closure member to the open configuration.

US Pat. No. 10,689,168

PLASTIC BOTTLE, IN PARTICULAR TOILET CLEANSER BOTTLE, AND ATTACHMENT AND BOTTLE CONTAINER FOR SUCH A PLASTIC BOTTLE

SHB GmbH, Crailsheim (DE...

1. A plastic bottle, comprising:a bottle container having a bottle shoulder and a bottle neck projecting from said bottle shoulder;
an attachment snap-connected, in a plug-fitting direction, with said bottle neck, said bottle neck having a first snap connection element and said attachment having a second snap connection element;
said attachment being an adapter attachment having an adapter neck for plug-fitting a closure cap; and
an anti-rotation feature configured between said attachment and said bottle container, said anti-rotation feature including:
two snap connection elements which, selectively or in combination, engage in one another such that said snap connection elements configure a form-fit acting in a circumferential direction and defining a first anti-rotation feature;
a first toothing, defining a second anti-rotation feature, configured circumferentially on said bottle neck; and
said bottle shoulder having an elevation which conjointly with said attachment configures a form-fit that acts in the circumferential direction and defines a third anti-rotation feature.

US Pat. No. 10,689,167

CONTAINER AND CAP

TOKYO LIGHT INDUSTRY CO.,...

1. A container comprising:a container body including a container opening portion; and
a cap attached to the container opening portion by capping,
the container opening portion including:
a large diameter opening portion disposed at an upper end of the container opening portion, and
a small diameter opening portion disposed under the large diameter opening portion and having an outer diameter smaller than an outer diameter of the large diameter opening portion,
the cap including:
a body portion,
a tubular main fitting wall portion disposed inside the body portion,
an annular space which is provided between the body portion and the main fitting wall portion, and in which the container opening portion is fitted,
a tubular sub-fitting wall portion formed in the annular space,
an annular wall portion which integrally extends from an inner wall surface of the main fitting wall portion toward a radial center and diagonally upward, and which includes an ejection hole in a radially central portion, and
a check valve which covers the annular wall portion from an upper side of the annular wall portion and which is configured to open and close the ejection hole as a valve portion is detached from or seated on an annular valve seat around the ejection hole wherein
when the cap is capped on the container opening portion, an inner wall surface of the sub-fitting wall portion of the cap and an outer wall surface of the large diameter opening portion of the container opening portion closely contact each other, and an outer wall surface of the main fitting wall portion of the cap and an inner wall surface of the small diameter opening portion of the container opening portion closely contact each other at a close contact portion, and
the check valve is positioned at the same level as the close contact portion in a horizontal direction.

US Pat. No. 10,689,166

LID AND CONTAINER INCLUDING THE SAME

1. A lid, comprising:a lid body having an outlet;
a sealing member connected to the lid body and configured for sealing the outlet in a sealing state, the sealing member comprising a first end, a middle part, and a second end;
a first magnetic member disposed inside the middle part of the sealing member;
a driving member mounted and movable inside the lid body and configured for pushing the sealing member to rotate and unseal the outlet;
a second magnetic member disposed inside the driving member; and
wherein the first magnetic member attracts the second magnetic member to maintain the sealing member at the sealing state.

US Pat. No. 10,689,165

RESERVOIR SYSTEMS FOR HAND-HELD SPRAY GUNS AND METHODS OF USE

3M Innovative Properties ...

1. A lid for a spray gun reservoir system comprising:a lid body comprising:
a spout;
a platform at least partially surrounding the spout, wherein the platform defines a major plane and a partial helical shape declining with respect to the major plane and revolving about a central axis of the spout; and
a wall comprising an outer face adjoining the platform and comprising a portion that is declining with respect to the major plane of the platform;
wherein the partial helical shape begins in the major plane and interrupts the declining portion of the outer face of the wall, and
wherein the lid is configured to directly or indirectly attach to a spray gun.

US Pat. No. 10,689,164

CONTAINER WITH HEAT-SEALED COMPOSITE PLASTIC AND METAL SCREW CLOSURE

SONOCO DEVELOPMENT, INC.,...

1. A container assembly comprising:a container having an open top end, the top end defining a rim, the rim defining an upper sealing surface formed of a heat-sealable material, the top end further defining an external screw thread extending helically along an outer surface of the top end at a location spaced below the rim;
a closure comprising a screw cap formed of plastic ring assembled with a separately formed disk inserted in the cap, the cap defining an internal screw thread extending helically along an inner surface of the cap and engageable with the external screw thread on the top end of the container for attaching the closure to the container when the closure is rotated in a first direction, the cap further comprising an inwardly projecting lip,
the disk being constructed of a laminated metal having an upper metal layer and a lower heat-sealable layer affixed to an underside of the metal layer and further comprising a raised peripheral bead and a curl located radially outward from the raised peripheral bead, wherein the raised peripheral bead of the disk is located between the inwardly projecting lip and an outer surface of the cap; and
a heat seal between the heat-sealable layer of the disk and the heat-sealable material of the upper sealing surface of the rim, the heat seal affixing the disk to the rim such that the disk seals closed the open top end of the container without depending on a continuous compressive force of the disk by the cap,
wherein the cap further consists of a single projection extending inwardly from the cap, wherein the projection does not extend fully circumferentially within the cap, and wherein the projection is structured and arranged such that as the cap is unscrewed, the projection exerts an upward force on a localized region of the disk's circumference and such that the localized region progresses around the circumference in the second direction as the closure is unscrewed, causing the heat seal to be broken between the disk and the upper sealing surface of the rim at the localized region to allow the disk to be detached from the rim.

US Pat. No. 10,689,163

DOSING DEVICE TO EQUIP A CONTAINER AND CONTAINER INCLUDING SUCH A DEVICE

ALBEA SERVICES, Gennevil...

1. A dosing device configured to equip a container comprising a deformable container containing a product, said device comprising an insert, said insert comprising a dosing chamber adapted to be deformed by pressure of the product coming from the reservoir, said dosing chamber comprising:a top valve for intake of the product from the reservoir, the top valve being open in an at rest position;
a bottom valve dispensing the product;
a deformable body connecting the top valve and the bottom valve;
the dosing chamber being configured so that, under the pressure of the product coming from the reservoir, the top valve is closed by the deformation of a first portion of the chamber, the bottom valve remaining closed, then the bottom valve opens under the effect of the deformation of the body.

US Pat. No. 10,689,162

BAG WITH ZIPPER TAPE

IDEMITSU UNITECH CO., LTD...

1. A zipper-tape bag comprising:a bag body defining a housing space for containing a content;
a zipper tape provided to an inside of the bag body, the inside of the bag body defining a first inner surface and a second inner surface facing the first surface, the zipper tape comprising:
a first member comprising a first belt-shaped base bonded to the first inner surface of the bag body, and a first engaging portion provided to the first belt-shaped base; and
a second member comprising a second belt-shaped base bonded to the second inner surface of the bag body, and a second engaging portion provided to the second belt-shaped base and engageable with the first engaging portion; and
a tab provided to an outside of the bag body at a position closer to the housing space than a bonded position of each of the first belt-shaped base and the second belt-shaped base;
wherein one of the first belt-shaped base and the second belt-shaped base is bonded to the bag body only at a portion near the housing space with respect to a position of the first engaging portion or the second engaging portion in the width direction, and
one of the first engaging portion and the second engaging portion comprises a neck area projecting from the first belt-shaped base or the second belt-shaped base, and
the first belt-shaped base or the second belt-shaped base from which the neck area projects comprises: a thickened area continuous in the width direction from a base end of the neck area, which projects from the first belt-shaped base or the second belt-shaped base, toward the tab; and a thinned area adjacent to the thickened area and thinner than the thickened area.

US Pat. No. 10,689,161

FASTENER WITH GUIDE POSTS AND METHODS THEREFOR

WL RECLOSABLES LLC, Fore...

1. A fastener, comprising:a male closure element comprising:
a base member;
one or more male interlocking members extending distally from a first side of the base member; and
a plurality of guide posts extending distally from a second side of the base member;
the plurality of guide posts defining boundaries of a sealing region to which a heat seal bar can thermally adhere a plastic web by passing between the plurality of guide posts, the sealing region defined by a planar portion of the base member that spans between inner surfaces the plurality of guide posts.