US Pat. No. 10,112,115

GAMECASTING TECHNIQUES

NVIDIA CORPORATION, Sant...

1. A computer-implemented method comprising:executing, on a computer device comprising a first display, an application program to generate video frames of game content;
causing the video frames to be displayed on the first display at a first frame rate;
compositing, at the computer device, at least one graphical user interface (GUI) element with the video frames to generate composited frames at a second frame rate;
causing the composited frames to be displayed on a second display coupled to a display interface of the computer device by transmitting the composited frames to the second display via the display interface of the computer device;
determining that the first frame rate is less than a threshold frame rate; and
in response to determining that the first frame rate is less than the threshold frame rate, decreasing the second frame rate.

US Pat. No. 10,112,113

PERSONALIZED DATA DRIVEN GAME TRAINING SYSTEM

SONY INTERACTIVE ENTERTAI...

1. A computer-implemented method comprising:detecting, by a computer system, an interest of a video game player in assistance with interacting with a context of a video game;
determining, by the computer system, an experience level of the video game player in playing the video game and an interaction of the video game player with the context;
selecting, by the computer system, an action for the assistance from potential actions, the action selected based on predicted outcomes of performing the potential actions given the experience level of the video game player, the potential actions and the predicted outcomes derived based on inputting data about the context, the experience level, and the interaction to an artificial intelligence (AI) model, the AI model trained based on historical interactions with the context of other video game players of different experience levels, and the action selected based on a predicted outcome for the action indicating that the AI model predicts a higher likelihood of success for the action relative to other actions from the potential actions; and
causing, by the computer system, a presentation about the action in response to detecting that the video game player needs the assistance.

US Pat. No. 10,112,112

SYSTEMS AND METHODS FOR INDICATING POSITIONS OF SELECTED SYMBOLS IN A TARGET SEQUENCE

Zynga Inc., San Francisc...

1. A computer-implemented method, comprising:receiving, from a player of an online game, a first selected sequence of symbols in a first game portion to be played in a first game move in the online game, the first game portion comprising display of one or more symbols, at respective display positions, for selection by the player;
in an automated operation using one more processors, identifying a first shared symbol present in both the first selected sequence and a target sequence obscured from display in a second game portion; and
responsive to the identifying:
changing the second game portion to concurrently reveal the first shared symbol at a first position in the target sequence while maintaining respective obscured display of each remaining symbol of the target sequence; and
presenting, in the first game portion, an animation that gradually removes the first shared symbol from the first game portion and shifts a particular symbol from its current display position to the respective display position occupied by the first shared symbol.

US Pat. No. 10,112,111

SPECTATOR VIEW PERSPECTIVES IN VR ENVIRONMENTS

Sony Interactive Entertai...

1. A method for processing virtual reality content for viewing by spectators, comprising,receiving, at a server, a virtual reality stream associated with interaction by a head mounted display (HMD) player wearing an HMD, the HMD player is configured to navigate a virtual reality environment, and the navigation of the virtual reality environment produces the virtual reality stream having an HMD player view;
receiving, at the server, a request via a device of a spectator to view the virtual reality stream via an HMD of the spectator;
sending, by the server, a feed of the virtual reality stream to the device of the spectator, the feed of the virtual reality stream providing an HMD spectator view into the virtual reality environment that is enabled to be a same view and distinct views relative to the HMD player view;
receiving, by the server, position information of the HMD of the spectator;
processing, by the server,
an up-scaling of a portion of the virtual reality environment when the position indicates that the HMD of the spectator has moved closer to content in the virtual reality environment;
a down-scaling of the portion of the virtual reality environment when the position indicates that the HMD of the spectator has moved further from content in the virtual reality environment.

US Pat. No. 10,112,110

INITIATING A GAME SESSION WITH BROADCAST SUBSCRIBERS

Amazon Technologies, Inc....

1. A system comprising:a game server, the game server programmed to perform operations comprising:
serving video game content for an online game to a plurality of game clients;
receiving from a game client a request to invite one or more subscribers to a content stream of the online game to participate in a game session; and
transmitting a request for subscribers to participate in a session of the online game, the request for subscribers comprising a game identifier identifying a game, a game session identifier identifying a game session, and information identifying characteristics of subscribers; and
a broadcast streaming server, the broadcast streaming server programmed to perform operations comprising:
serving a content stream of the online game to a plurality of streaming server clients;
receiving the request for subscribers to participate in a session of the online game;
determining a subscriber who is authorized to participate in the game session based at least in part on the game identifier and the identified characteristics;
transmitting to a user node having a streaming server client executing thereon associated with the subscriber who is authorized to participate in the game session, instructions to provide notice of the request for subscribers to participate in the game session;
receiving from the streaming server client associated with the subscriber who is authorized to participate in the game session a request to join the game session;
transmitting to the game server a request to join the game session, the request to join the game session comprising information identifying the subscriber who is authorized to participate in the game session;
determining instructions for launching a game client at the user node and for accessing the game session using the game client; and
transmitting to the user node the game session identifier identifying the game session and the determined instructions for launching a game client at the user node and for accessing the game session using the game client.

US Pat. No. 10,112,109

SHARED MULTIMEDIA EXPERIENCE INCLUDING USER INPUT

1. A multimedia distribution method comprising:providing multimedia content to a plurality of network clients via a multimedia network;
accessing user profiles corresponding to at least some of the network clients;
identifying, from collaboration group information included in at least some of the user profiles, a plurality of collaboration groups, including a first collaboration group and a second collaboration group, and a plurality of members of each of the collaboration groups;
sending a question pertaining to the multimedia content to each of the collaboration groups;
receiving responses to the question, wherein each of the responses includes a timestamp indicative of when the response was generated and a proposed answer to the question wherein the responses include a first response from the first collaboration group and a second response from the second collaboration group wherein the first response includes a first proposed answer to the question and the second response includes a second proposed answer to the question;
modifying the multimedia content provided to the first collaboration group to include the second proposed answer and modifying the multimedia content provided to the second collaboration group to include the proposed answer;
evaluating the first proposed and the second proposed answer to the question; and
determining, based on the timestamps and the evaluating of the first proposed answer and the second proposed answer, a winning response for each of the collaboration groups.

US Pat. No. 10,112,108

CONTENT-RELATED INFORMATION DISPLAY SYSTEM

KABUSHIKI KAISHA SQUARE E...

1. A content-related information display system, comprising:a first apparatus including:
a first memory that stores content;
a first processor that outputs a drawing command for displaying the content on a first display, and generates progress status information which is related to a progress status of the content;
the first display that displays the content; and
a first interface that transmits the progress status information; and
a second apparatus including:
a second interface that receives the progress status information transmitted by the first interface of the first apparatus;
a second memory that stores content-related information which is related to the content;
a second processor that specifies the content-related information to be displayed on a second display, the content-related information being specified according to the progress status information received by the second interface and generated by the first processor; and
the second display that displays the content-related information,
wherein more detailed information is displayed on the second display than on the first display,
the content-related information is preset in the second memory,
the first display is not configured to display the content-related information, and
the first processor generates the progress status information and the second processor specifies the content-related information in response to at least one of a predetermined condition being satisfied in relation to the progress status of the content or a specific operation being received by the first processor in relation to the progress status of the content.

US Pat. No. 10,112,107

IDENTIFICATION APPARATUS

1. An identification apparatus for reading an ID of an identification object, comprising:a sensor face in which a plurality of sensor electrodes serving for detecting a change of electrostatic capacitance, and a ground portion provided separately from the sensor electrodes are provided on one and the same plane; wherein:
a conductive portion or conductive portions formed in the identification object is configured so that when the identification object is placed on the sensor face, the conductive portion or the conductive portions can electrically connect a corresponding one or corresponding ones of the sensor electrodes with the ground portion; and
a change of electrostatic capacitance occurring when the corresponding sensor electrode or electrodes are electrically connected with the ground portion is detected so that the ID of the identification object can be identified.

US Pat. No. 10,112,106

GAMING KIT FOR USE WITH ROLLING TARGET TOSSING GAME

1. A gaming kit for use by at least two players for playing a tossing and rolling game on a gaming surface, the gaming kit comprising:a. at least one target zone marker configured to be placed on the gaming surface, wherein each of the at least one target zone markers is further configured to identify a target zone area on the gaming surface;
b. one rolling piece comprising at least six side face surfaces, wherein each of the at least one rolling pieces is configured to be rolled across the gaming surface toward the target zone markers and come to rest at a resting point on the gaming surface relative to one of the at least one target zone markers; and
c. at least one tossing piece configured to be tossed toward one of the rolling pieces on the gaming surface, wherein each of the at least one tossing piece is configured to land at one of a plurality of landing positions relative to the at least one rolling piece,
wherein at least a portion of the side face surfaces of each of the at least one rolling pieces comprises a recessed portion configured to act as a compartment for receiving the at least one tossing piece.

US Pat. No. 10,112,105

TABLE GAME SYSTEM

ANGEL PLAYING CARDS CO., ...

1. A table game system comprising:shuffled playing cards composed of playing cards made up of a plurality of number of decks shuffled to have a unique arrangement order, a uniquely identifiable shuffled card ID being attached to the shuffled playing cards as an ID code;
a card shoe apparatus that houses the shuffled playing cards in a card housing unit such that the said shuffled playing cards can be manually dealt one by one onto a game table and reads from the card a code printed on the card concerning the rank thereof via a card reading unit;
a barcode reader or an input means for information that identifies the shuffled card ID capable of identifying the shuffled card ID, and
a control unit that includes a memory for storing a plurality of association tables or a plurality of databases, each of which makes it possible to obtain the rank of each card based on the code of each card,
wherein each association table or database is recorded in association with the shuffled card ID, and one of the plurality of association tables or databases is identified by identifying the shuffled card ID, and based on the association table or database identified, the card reading unit reads the code when each card is drawn from the card housing unit and the rank of the card is identified based on that code.

US Pat. No. 10,112,104

SNOWSHOE WITH MULTI-DENSITY FOAM DECK

Cresent Moon Snowshoes, I...

1. A snowshoe comprising:a deck for providing floatation in snow, said deck having a front portion adjacent a front end of said deck, a back portion adjacent a back end of said deck, and a middle portion between said front portion and said back portion; and
a binding for attaching the deck to a user's footwear;
wherein said deck has a multi-density foam construction including a first layer having a first density and a second layer having a second density different than said first density, and said deck has thickness that is greater in said middle portion than in said front and back portions, said deck having a bottom surface that is continuously curved from said front end to said back end, said bottom surface having a first nonzero curvature at said front portion, a second nonzero curvature at said back portion, and a third nonzero curvature at said middle portion, wherein the third curvature is less than the first and second curvatures.

US Pat. No. 10,112,103

SPLITBOARD JOINING DEVICE

1. A splitboard joining device comprising:a first attachment configured to attach to a first ski of a splitboard;
a second attachment configured to attach to a second ski of a splitboard;
wherein the first attachment and the second attachment comprise a first configuration where the first attachment and the second attachment are joined, thereby creating tension between the first attachment and the second attachment and compression between the first ski and the second ski;
wherein the first attachment and the second attachment comprise a second configuration where the first attachment and the second attachment are disengaged, thereby reducing tension between the first attachment and the second attachment, and reducing compression between the first ski and second ski;
wherein the first attachment and the second attachment comprise a third configuration where the first attachment and the second attachment are fully disengaged such that the first ski and the second ski can be separated for use in tour mode;
wherein the first attachment and the second attachment can only move to the third configuration from the second configuration, and wherein to move from the second configuration to the third configuration the first attachment is configured to move away from the second attachment in a direction generally parallel to the seam of the splitboard and in a direction generally in plane with the top of the first ski and the top of the second ski;
wherein the first attachment comprises a tensioning element movable in a plane generally parallel to the top of the first ski and second ski, and wherein the second attachment comprises a receiving element configured to engage the tensioning element of the first attachment wherein the receiving element is also configured to extend generally perpendicular to a tensioning direction and offset from a mounting position of the second attachment of the second ski;
wherein the tensioning element is movable between a first position and a second position, and wherein the first attachment and the second attachment are configured such that when the tensioning element is in the first position and engaged with the receiving element of the second attachment, the first attachment and second attachment are in the first configuration;
wherein the first attachment and the second attachment are configured such that when the tensioning element is in the second position and has reduced engagement with the receiving element of the second attachment, the first attachment and second attachment are in the second configuration;
wherein the splitboard joining device further comprises an adjustable tension element configured to adjustably control the tension between the first attachment and the second attachment and configured to adjustably control the compression between the first and second skis when coupled, when the first attachment and second attachment are in the first configuration.

US Pat. No. 10,112,102

SYSTEM FOR ENERGY ON-SITE COLLECTION AND MEASUREMENT FEEDBACK

Xiao Hu, Shenzhen, Guang...

1. A system for energy collection and measurement, comprising:a plurality of fitness apparatuses, each apparatus producing mechanical energy,
a plurality of generators, each connected to a respective fitness apparatus such that operation of the respective fitness apparatus induces the respective generator to produce electrical energy corresponding to the produced mechanical energy,
a plurality of changeable energy storage accumulators connected with respective generators so as to selectively store electrical energy produced and include alarm systems providing a full-power alarm when a changeable energy storage accumulator is fully charged to indicate readiness for replacement,
a plurality of power meters with display screens, each power meter connected between a respective generator and accumulator, to respectively measure and display an equivalent currency amount of the electrical energy produced,
a plurality of two-step bank card readers, each connected with a respective power meter so as to first register an individual user and then, after an initial interval of at least five minutes, read and update data of a bank card associated with the individual user of a respective fitness apparatus and with the respective generator so as to sum a new equivalent currency amount to an existing currency balance of the individual user proportionate to an amount of electrical power produced by the respective generator during the individual's operation of the fitness apparatus at following intervals of one minute,
chargeable light-emitting devices connected with the energy storage accumulators and switches controlling the operating state of each light emitting device,
a data processing host in communication with all of the bank card readers, light-emitting devices, and power meters at an exercise site such that data of all of the power meters is transmitted to the data processing host and summarized and the data processing host can change passwords and inquire about power storage capacity of a given user and a corresponding currency amount thereof and wherein the electrical power produced is directed to charge the chargeable light-emitting devices until the light-emitting devices are fully charged and is then directed to charge the accumulators, and
a keyboard connected with the data processing host.

US Pat. No. 10,112,101

INFORMATION-PRESENTATION STRUCTURE WITH IMPACT-SENSITIVE COLOR CHANGE AND SOUND GENERATION

1. An information-presentation (“IP”) structure comprising:an object-impact (“OI”) structure having an exposed surface for being impacted by an object during an activity, the OI structure comprising a variable-color (“VC”) region which extends to the exposed surface at a surface zone and normally appears along it largely as a principal color during the activity, an impact-dependent (“ID”) portion of the VC region responding to the object impacting the surface zone at an ID object-contact (“OC”) area spanning where the object contacts the surface zone by temporarily appearing along an ID print area of the surface zone largely as changed color materially different from the principal color if the impact meets threshold impact criteria, the print area at least partly encompassing, at least mostly outwardly conforming largely to, and being largely concentric with the OC area; and
sound-generating apparatus for selectively generating a specified audible sound in response to the object impacting the OC area so as to meet the threshold impact criteria, the specified sound being separate from any audible sound originating at the OC area due physically to the impact.

US Pat. No. 10,112,100

COMPUTER-IMPLEMENTED METHODS AND SYSTEMS ENABLING FAN PARTICIPATION IN CALLING PLAYS AT SPORTING AND OTHER EVENTS

Your Call Technology, LLC...

1. A computerized method of determining a score for a user of a gaming platform such that the score reflects the user's success rate in calling plays in a sporting event, the method comprising:receiving, by a computing device, a user profile, the user profile corresponding to a user registered to vote in a real-time game, the user profile comprising a user vote performance score;
initiating, by the computing device, a sequence of states in response to a start of a play during the real-time event, the sequence of states comprising:
a poll creation state, the poll creation state comprising receiving, by the computing device, a set of plays from a coordinator computing device at a time corresponding to a time prior to an execution of a play in the real-time event,
a first notification state, the first notification state comprising sending, by the computing device, the set of plays to a registered user computing device and the coordinator computing device in a format such that the sets of plays automatically displays on the registered user computing device and the coordinator computing device,
a coordinator pick state, the coordinator pick state comprising receiving, by the computing device, a coordinator pick from the coordinator computing device, the coordinator pick corresponding to one play from the set of plays,
a fan voting state, the fan voting state comprising receiving, by the computing device, a fan vote from the registered user computing device, the fan vote corresponding to one play from the set of plays,
a second notification state, the second notification state comprising sending, by the computing device, a winning play to the registered user computing device and the coordinator computing device, the winning play based on results of the vote, and
a play in action state, the play in action state comprising receiving, by the computing device, an on-field result associated with a real-time play based on the winning play from an administrator computing device;
calculating, by the computing device, a field score associated with the real-time play, the field score comprising points allocated based on at least one event associated with the on-field result during the real-time play, the field score comprising a positive value when the on-field result comprises a good result and a negative value when the on-field result comprises a bad result; and
updating, by the computing device, a user vote performance score, the user vote performance score associated with points awarded based on the fan vote and at least one of the coordinator pick, the winning play, and the field score.

US Pat. No. 10,112,099

PUTTING TRAINING APPARATUS

1. A putting training apparatus comprising:an elongated planar member including:
a bottom surface;
an top surface; and
an aperture;
wherein said aperture extends from and through said top surface to and through said bottom surface;
wherein said elongated planar member planar member is adapted to lie over a ground surface with said bottom surface in contact with said ground surface;
a putting cup;
wherein said putting cup is installed within said aperture and is adapted to receive a golf ball;
a golf ball;
a golf ball positioning mark;
wherein said golf ball positioning mark is imprinted upon said top surface of the planar member;
a first line;
wherein said first line extends linearly from said golf ball positioning mark to said putting cup forming a putting line; and
wherein said first line includes at least one ball positioning mark imprinted along said putting line;
at least one elongated guiding line;
wherein said at least one elongated guiding line is imprinted linearly upon said top surface of said planar member parallel to said putting line and adjacent to said golf ball positioning mark;
a dome member;
wherein said dome member is adapted to be installed upon said putting cup and adapted to make a sound when said golf ball is received within said putting cup;
a putter member including:
a crown portion;
wherein said crown portion includes a line drawn thereon adapted to be visible by a golfer when in use, such that said line is adapted to be placed substantially parallel to said guiding line when said putter member is properly aligned with said putter line; and
an elongated and thin guiding member including:
a head portion; and
a body portion;
wherein said guiding member is removably coupled to said crown portion of said putter member via said body portion, and said head portion is adapted to point towards said at least one elongated guiding line;
wherein said guiding member is adapted to serve as a visual aid to orient said putter member along said putting line and stroking said golf ball along said guiding line.

US Pat. No. 10,112,098

BICYCLE TRAINER

Tacx roerend en onroerend...

1. A bicycle trainer for removably loading a bicycle with at least a back wheel, where the bicycle trainer comprises a floorstanding frame with a wheel supporting roller at a rear end and a fork supporting unit at a front end, wherein the fork supporting unit is pivotally supported by the floorstanding frame enabling the fork supporting unit to move back-and-forth, characterized in that the fork supporting unit and the floorstanding frame connect to each other with a hinge enabling back-and-forth movement of the fork supporting unit in a longitudinal direction of the floorstanding frame, wherein the fork supporting unit is spring-loaded with a spring at or near the hinge to provide the fork supporting unit with a preferential upright position at right angles with the floorstanding frame such that whenever the bicycle is moved forward or backward, said bicycle is biased by said spring to return to an average position on the bicycle trainer wherein the fork support unit is at right angles with the floorstanding frame.

US Pat. No. 10,112,096

HOCKEY TRAINING DEVICE

Steven Taylor, Toronto, ...

1. A hockey training device comprising:a connector assembly adapted to engage a blade of a hockey stick; and
a puck holding assembly;
a hinge provided between the connector assembly and the puck holding assembly; wherein the hinge permits the puck holding assembly and the connector assembly to pivot relative to each other.

US Pat. No. 10,112,095

SPORTS TRAINING DEVICE

Mr. Assist LLC, Westwood...

1. A sports training device, comprising:a circular main housing having opposed top and bottom surfaces each having a plurality of bosses formed thereon,
a channel formed within an intermediate housing section of the main housing and extending therethrough,
a fastening mechanism seated within the channel and secured to the main housing by a fastener, wherein the fastener mechanism includes a first fastener part and a separate and independent second fastener part, wherein the first fastener part and the second fastener part can be coupled together, and
a cord element having a first end portion mounted between the first fastener part and the second fastener part and being mechanically retained therebetween, wherein the cord element extends outwardly from the channel,
wherein the first fastener part comprises a main body having
a first end that includes a first skirt portion and an opposed second end that has a second skirt portion that forms a lip portion, wherein the lip portion projects in a direction opposite to a projection direction of first skirt portion, and
one or more cut-out portion that forms an outwardly projecting tab, and
wherein the second fastener part comprises a main body having
a first end that includes a first skirt portion and an opposed second end that has a skirt portion that forms a lip, wherein the lip portion projects in a direction opposite to a projection direction of the first skirt portion, and
one or more cut-out portions that form a pair of outwardly projecting tabs that are axially spaced apart along the main body.

US Pat. No. 10,112,094

SOCCER TRAINING ARENA

1. A soccer training facility for use by a soccer player, comprising:an upstanding wall extending substantially around a training space positioned on a support surface;
said wall having an upper end, a lower end, an inner side and an outer side;
said wall further including:
(a) an elongated, horizontally disposed base plate positioned at said lower end of said wall and supported on the support surface; and
(b) an elongated, horizontally disposed top plate positioned at said upper end of said wall;
a plurality of horizontally spaced-apart recessed openings formed in said lower end of said wall;
each of said plurality of recessed openings having a generally rectangular-shape and having a lower end, an upper end, a first end and a second end; and further including
a pair of vertically disposed studs, each having a lower end and an upper end, and a pair of elongated, horizontal upper and lower support members, each respectively disposed between said lower and upper ends of said pair of vertically disposed studs;
wherein said lower end of each said pair of studs including:
a plurality of spring mounts;
a plurality of connector elements, each having an inner end and an outer end, movably positioned within a corresponding spring mount of the plurality of spring mounts with said outer end connected to the respective spring mount, the plurality of connector elements movable between an inner position and an outer position with respect to a respective spring mount;
a plurality of springs associated with said plurality of spring mounts and plurality of connector elements, each spring of the plurality of springs, yieldably urging the respective connector element to said inner position;
a pivotable, generally rectangular-shaped training target positioned in each of said plurality of recessed openings;
each of said plurality of training targets having an inner side, an outer side, a lower end, an upper end, a first end and a second end;
said inner end of each of the connector elements being secured to said first and second ends and upper and lower ends of each of said plurality of training targets;
wherein each of said plurality of training targets is movable with respect to each respective recessed opening between an outer position and an inner position;
wherein each spring of the respective plurality of springs, yieldably maintains the respective training target in said inner position;
each of said plurality of training targets being moved from said respective inner position to said respective outer position upon said respective inner sides thereof being struck by a soccer ball;
each of said plurality of target openings further including a light assembly associated therewith; each of said light assemblies including:
(a) a support frame secured within said recessed opening formed within said wall;
(b) an illumination means having an upper light member, a first side light member and a second side light member, wherein said illumination means is secured to said support frame and extends around a perimeter of each of said plurality of training targets; and
wherein said light assemblies illuminating said plurality of training targets when activated.

US Pat. No. 10,112,092

PIVOTING SOCCER GOAL AND GAME

1. A soccer goal comprising:a. an upright frame having a horizontally disposed bottom member, said member having a left end, a right end, an upstanding left arm connected to said left end of said horizontally disposed bottom member and an upstanding right arm connected to said right end of said horizontally disposed bottom member and a net fastened to said frame;
b. a base connected to a center portion of said horizontally disposed bottom member;
c. a turntable connected to said base and said turntable further comprising an upper turntable member connected to a lower turntable member;
d. a mat placed on the ground about said soccer goal and connected to said lower turntable member whereby said soccer goal rotates when subjected to forces such as a kicked soccer ball and a soccer ball can enter said net regardless of the direction from which said soccer ball approaches said soccer goal; and
e. a skirt detachably connected to a perimeter of said mat whereby said skirt provides a shallow low angle from the ground to the mat, whereby travel of the soccer ball into the soccer goal is facilitated.

US Pat. No. 10,112,089

LACROSSE HEAD POCKET AND RELATED METHOD OF MANUFACTURE

Warrior Sports, Inc., Wa...

1. A lacrosse pocket comprising:a pocket longitudinal axis;
an upper pocket portion adapted to connect to a lacrosse head scoop;
a lower pocket portion adapted to connect to a lacrosse head base;
a middle pocket portion located between the upper pocket portion and the lower pocket portion;
a unitary textile material extending from the upper pocket portion to the lower pocket portion, the unitary textile material constructed from a plurality of strands,
wherein the unitary textile material includes a first layer and a second layer, one above the other, and each of the first layer and the second layer integrally formed in the unitary textile material, the first layer and second layer collectively forming a first tube having an open space between the first layer and the second layer,
wherein the first layer includes a first interior facing surface and the second layer includes a second interior facing surface,
wherein the first interior facing surface is disposed above the second interior facing surface and configured to randomly contact the second interior facing surface in regions where the first tube is collapsed.

US Pat. No. 10,112,088

GOLF FLAG MARKER

1. An attachment for a golf flag stick comprising:a hub constructed of a flexible resilient material, said hub having a central opening dimensioned to receive and resiliently grip the golf flag, said hub having a first slot communicating with the central opening,
a plurality of spokes, each spoke having an inner end attached to said hub, said spokes extending substantially radially outwardly from said hub and engaging, at outer ends, to a ring constructed of a flexible resilient material and surrounding said hub, a second slot in said ring communicating an exterior of said ring with said hub,
a subset pair of said plurality of spokes located on opposite sides of each of said first and second slots; and
separating said subset pair of spokes causing flexing of both said hub and ring for facilitating passage of the golf stick between the exterior of said ring and the central opening of said hub and/or for reposition-ably adjusting said hub at locations along the flag stick.

US Pat. No. 10,112,087

GRIP AND METHOD OF MAKING A GRIP

1. A grip configured to be grasped by a user, said grip comprising:a tube having a body with a first end, a second end including a cover, a support surface positioned between said first and second ends and at least one raised portion extending outwards from said support surface and integrally formed with said support surface, said second end including a second end portion integrally formed with said support surface and extending radially outwards from said support surface, said second end portion extending from said cover at least about one half inch toward said first end around the circumference of said tube;
said at least one raised portion including an exposed surface, said at least one raised portion extending to an elliptical-like point positioned within one-third of the length of said tube from said first end, said second end portion and said at least one raised portion separated by said support surface;
a gripping member wrapped about and contacting said support surface and not said exposed surface of said at least one raised portion; and
wherein an outer surface of said gripping member and said exposed surface of said at least one raised portion cooperate to define a gripping surface positioned to be gripped by a user and wherein said outer surface of said gripping member and said second end portion extend substantially the same distance from said support surface.

US Pat. No. 10,112,086

ASCENDING WEIGHT IRON SHAFT SYSTEM

Karsten Manufacturing Cor...

1. A plurality of starting stocks for manufacturing shafts of a system of golf clubs, comprising:a plurality of first starting stocks having a first average outer diameter, a first average inner diameter, a first average cross-sectional area, and first average weight-to-length ratio;
a plurality of second starting stocks having a second average outer diameter, a second average inner diameter, a second average cross-sectional area, and a second average weight-to-length ratio, wherein the second average weight-to-length ratio is greater than the first average weight-to-length ratio;
wherein one of the plurality of first starting stocks is configured to be cut to a first length, resulting in a first shaft having a first weight, the first shaft being assembled to a first club head with a first loft angle to make a first golf club in a particular stiffness class;
wherein one of the plurality of second starting stocks is configured to be cut to a second length, resulting in a second shaft having a second weight, the second shaft being assembled to a second club head with a second loft angle to make a second golf club in the same stiffness class as the first golf club, wherein the second weight is greater than the first weight, the second length is less than the first length, and the second loft is greater than the first loft;
wherein one of the plurality of first starting stocks is configured to be cut to a third length, resulting in a third shaft having a third weight, the third shaft being assembled to a third club head with a third loft angle to make a third golf club in a smaller stiffness class than the first golf club, wherein the third weight is less than the first weight, the third length is less than the first length and the third loft is greater than the first loft;
wherein one of the plurality of second starting stocks is configured to be cut to a fourth length, resulting in a fourth shaft having a fourth weight, the fourth shaft being assembled to a fourth club head with a fourth loft angle to make a fourth golf club in a smaller stiffness class than the second golf club, wherein the fourth weight is less than the second weight, the fourth length is less than the second length and the fourth loft is greater than the first loft;
wherein one of the plurality of first starting stocks is configured to be cut to a fifth length, resulting in a fifth shaft having a fifth weight, the fifth shaft may be assembled to a fifth club head with a fifth loft angle to make a fifth golf club in a greater stiffness class than the first golf club, wherein the fifth weight is greater than the first weight, the fifth length is greater than the first length and the fifth loft is less than the first loft;
wherein one of the plurality of second starting stocks is configured to be cut to a sixth length, resulting in a sixth shaft having a sixth weight, the sixth shaft may be assembled to a sixth club head with a sixth loft angle to make a sixth golf club in a greater stiffness class than the second golf club, wherein the sixth weight is greater than the second weight, the sixth length is greater than the second length, and the sixth loft is less than the first loft.

US Pat. No. 10,112,085

GOLF CLUB HEAD WITH REPOSITIONABLE WEIGHT

Taylor Made Golf Company,...

1. A golf club head, comprising:a body having a sole, a crown, a face at a forward end of the body, and a ribbon extending between the crown and the sole;
a channel being formed in or attached to the ribbon of the body, the channel having a length, the channel having two spaced apart channel walls and a bottom formed by an outer surface of the body;
at least one weight and weight retainer, the weight and weight retainer being continuously repositionable such that the weight can be positioned at any selected position along the channel, wherein the weight and weight retainer are retained and moveable within the channel, and wherein a fastening member threadably engages at least one of the weight and the weight retainer,
wherein at least one of the weight and the weight retainer is shaped such that at least one dimension of at least one of the weight and the weight retainer is larger than a width of the channel;
wherein the weight is a first weight, further comprising a second weight movable independently of the first weight;
wherein the weight is dimensioned to be received in and slidably movable within the channel.

US Pat. No. 10,112,083

GOLF CLUBS WITH ADJUSTABLE LIE AND LOFT AND METHODS OF MANUFACTURING GOLF CLUBS WITH ADJUSTABLE LIE AND LOFT

Karsten Manufacturing Cor...

1. A golf club head comprising:a body having a top rail portion, a sole portion, and a recess portion extending between the top rail portion and the sole portion;
a hosel comprising a first end configured to rotationally connect to the body and a second end configured to receive a shaft,
wherein the hosel comprises a front side, a toe side, a heel side, and a rear side,
wherein the hosel first end comprises a curvature from the hosel front side to the hosel rear side,
wherein the body further comprises a slot configured to receive the first end of the hosel,
wherein the slot comprises a top side, a front side, a toe side, a heel side, and a rear side,
wherein the slot top side comprises a curvature from the slot front side to the slot rear side,
wherein the hosel is connected in the slot with at least one pin extending through the body and engaged in a bore in the hosel, and
wherein the bore in the hosel defines an axis of rotation of the hosel relative to the body,
wherein the bore in the hosel extends from the heel side of the hosel through to the toe side of the hosel,
and
an insert configured to be inserted in the recess portion and coupled to the first end of the hosel,
the insert configured to be positioned in the recess portion at one rotational position of a plurality of different rotational positions corresponding to a plurality of different angles between the body and the shaft,
wherein the first end of the hosel comprises a bolt configured to be inserted through the insert and engaged with a threaded bore from the sole portion to fix the body relative to the shaft at the one rotational position.

US Pat. No. 10,112,082

BALL WITH INCREASED FLEXURE

1. An object for sports play comprising:a plurality of exterior panels, stitched together at their edges, configured to form a closed volume and forming, by said stitching, raised interior ridges at the edges of said exterior panels so that each exterior panel has associated therewith a recessed area essentially coextensive with said exterior panel and defined by said raised interior ridges;
an inflatable bladder occupying said closed volume;
a plurality of flat adjacently disposed interior cushioning panels, said interior panels individually having a layered structure including a first layer which occupies said recessed area and a second layer having a portion which is wider than said first layer, the wider portion of said second layer being disposed between said bladder and said raised interior ridges and separate from said raised interior ridges, said adjacently disposed interior cushioning panels having the same shape as said corresponding recessed area, said second layers of said interior panels abutting one another at their edges directly beneath said stitching.

US Pat. No. 10,112,081

GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER

Acushnet Company, Fairha...

1. A golf ball comprising:a core having an outer surface, a geometric center, and a soft transition region adjacent to the outer surface, the soft transition region having a thickness of about 4 mm or less and comprising about 10 percent to about 45 percent of a trans-polybutadiene isomer; and
wherein the core has an outer surface hardness greater than a hardness at the geometric center to define a positive hardness gradient of about 12 Shore C to 68 Shore C; and a secondary gradient quotient, GQ?, from about 4 to 13, GQ? being defined by the equation:

where G? is the core positive hardness gradient in Shore C, T is the percent of trans-polybutadiene isomer at the core outer surface, and COR is the coefficient of restitution of the core measured at an incoming velocity of 125 ft/s; and
an outer cover layer formed from a thermoset polyurethane material throughout and having a treated region including at least a cover outer surface and an untreated region extending from a cover inner surface to the treated region;
wherein the treated region is contacted with a thermoset polyurethane microhardness-increasing solution consisting of an isocyanate portion and at least one non-aqueous solvent;
wherein the treated region comprises the isocyanate portion and has a microhardness M1 that is greater than a microhardness M2 of the untreated region, wherein the untreated region is not contacted with the thermoset polyurethane microhardness-increasing solution and does not comprise the isocyanate portion.

US Pat. No. 10,112,080

GOLF BALLS HAVING FOAM CENTER AND THERMOSET OUTER CORE LAYER WITH HARDNESS GRADIENTS

Acushnet Company, Fairha...

1. A core assembly for a golf ball, comprising:i) an inner core layer comprising a foamed composition, the inner core layer having a diameter in the range of about 0.100 to about 1.100 inches, a specific gravity (SGinner), and an outer surface hardness (Hinner core surface) and a center hardness (Hinner core center), the Hinner core surface being greater than the Hinner core center to provide a positive hardness gradient;
ii) an outer core layer comprising a thermoset material, the outer core layer being disposed about the inner core layer and having a thickness in the range of about 0.100 to about 0.750 inches, a specific gravity (SGouter), and an outer surface hardness (Houter surface of OC) and an inner surface hardness (Hinner surface of OC), the Houter surface of OC being the same or less than the Hinner surface of OC to provide a zero or negative hardness gradient,
wherein the SGouter, is greater than the SGinner, and the center hardness of the inner core (Hinner core center) is in the range of about 10 Shore C to about 60 Shore C and the outer surface hardness of the outer core layer (Houter surface of OC) is in the range of about 40 Shore C to about 90 Shore C to provide a positive hardness gradient across the core assembly.

US Pat. No. 10,112,079

FLIPPERS, BOOTS, SYSTEMS INCLUDING SAME, AND METHODS OF USING SAME

Cetatek Holdings Inc., B...

1. A method of coupling a boot body to a fin apparatus comprising a fin body coupled to a foot coupling portion, the method comprising:connecting a first boot connector on the foot coupling portion to a first complementary boot connector on a top side of the boot body; and
connecting a second boot connector on the foot coupling portion to a second complementary boot connector on a bottom side of the boot body;
wherein connecting the second boot connector to the second complementary boot connector comprises positioning a holding surface of the second boot connector against a retaining surface on the bottom side of the boot body; and
wherein the retaining surface on the bottom side of the boot body is positioned to retain the second boot connector against movement in a direction towards the fin body when the holding surface of the second boot connector is positioned against the retaining surface on the bottom side of the boot body.

US Pat. No. 10,112,078

STEP ASSEMBLY WITH FALL ARREST CAPABILITY INCLUDING REMOVABLE STEP

VAF Industries, LLC, Esc...

1. A step assembly with fall arrest capability for use for climbing a utility structure, the step assembly comprising:a step unit comprising:
a rod having a flat surface along a longitudinal direction for placing a foot thereon for climbing,
two leg members transversally coupled to the rod, and
a loop section attached to the rod, on a side opposite to the flat surface, wherein two end portions of the loop section are attached at different points of the rod, thereby providing a generally D-shaped opening defined by the loop section and part of the rod between the two end portions of the loop section;
a leg holder comprising:
a center plate having a circular opening, and
two cylinders formed along two side edges of the center plate, respectively, wherein the two cylinders are configured for the two leg members to be inserted therethrough, respectively; and
an expansion anchor comprising:
a fin unit comprising a plurality of fins cylindrically disposed, each fin having a generally rectangle portion and a shoulder section formed contiguous to the rectangle portion, the shoulder section having a transversal dimension smaller than that of the generally rectangle portion;
wherein a combination of the leg holder and the expansion anchor is configured by inserting the expansion anchor through the circular opening of the center plate of the leg holder to have the plurality of fins on one side of the center plate, and the combination is configured to be secured with the utility structure based on bending the plurality of fins at the shoulder sections to have the plurality of fins opened inside the utility structure while the leg holder is in contact with and outside the utility structure, and
wherein the step unit is detachably attached to the secured combination by inserting the two leg members through the two cylinders of the leg holder, respectively.

US Pat. No. 10,112,077

ELECTRIC TRAINING APPARATUS AND EXERCISE CONTROL METHOD THEREFOR

MITSUBISHI ELECTRIC ENGIN...

1. An electric training apparatus, comprising:a rotating body configured to apply a load on an exercising person;
a load motor configured to apply a load on the rotating body via a transmission mechanism;
an exercise physiological response detection unit configured to detect an exercise physiological response value of the exercising person;
a number-of-revolutions detection unit configured to detect a number of revolutions of the rotating body;
a control unit comprising an exercise control unit, the exercise control unit being configured to perform control for gradually increasing, based on a detection result from the exercise physiological response detection unit and a detection result from the number-of-revolutions detection unit, the load of the load motor toward a set load upper limit value so that the detection result of the exercise physiological response value of the exercising person approaches a target exercise physiological response value set in advance;
a display unit configured to display the detection result from the exercise physiological response detection unit, the detection result from the number-of-revolutions detection unit, and a state of the control of the control unit; and
an input unit configured to input a control command to the control unit,
the exercise control unit being configured to change the set load upper limit value in response to the control command input from the input unit before an exercise and during the exercise by the exercising person.

US Pat. No. 10,112,076

ROBOTIC ATHLETIC TRAINING OR SPORTING METHOD, APPARATUS, SYSTEM, AND COMPUTER PROGRAM PRODUCT

Christopher DeCarlo, Fai...

1. A sporting robotic device apparatus comprising:at least one or more of:
a plurality of sporting devices coupled to at least one robot; or
a plurality of said at least one robots, wherein said plurality of robots each comprise a sporting device coupled to said each of said plurality of robots; and
wherein said at least one robot comprises:
a plurality of joint axes,
wherein each joint axis of said plurality of joint axes comprises:
at least one motor;
at least one structural member coupled to at least one of said each of said plurality of joint axes motors,
wherein each of said at least one motor is configured to move an associated coupled at least one of said at least one structural member; and
wherein the sporting robotic device apparatus further comprises:
at least one electronic user interface coupled to said at least one robot or said plurality of robots, configured to interact with a user to receive a selection of at least one sporting routine for moving said plurality of sporting devices or said sporting device;
at least one electronic computer processor, coupled to said at least one robot, or said plurality of robots;
at least one electronic input device coupled to said at least one electronic computer processor;
at least one electronic output device coupled to said at least one electronic computer processor;
at least one electronic memory device coupled to said at least one electronic computer processor; and
further comprising at least one or more of:
wherein said electronic user interface comprises at least one of:
an electronic display device,
said at least one electronic input device,
said at least one electronic output device,
an electronic keyboard, or
an electronic touchscreen;
wherein said at least one electronic computer processor is configured to save or retrieve said at least one sporting routine from said at least one memory;
wherein said at least one electronic computer processor is configured to randomize at least one challenge by said at least one sporting device; or
wherein said electronic computer processor is configured to at least one or more of:
combine a plurality of previously saved of said at least one sporting routine, or
shuffle a plurality of previously saved of said at least one sporting routine.

US Pat. No. 10,112,074

SIGNAL ANALYSIS AND RECHARGING SYSTEM

1. A golf club impact analysis system, including:a first piezoelectric element embedded in a club face of a golf club;
a first signal divider that receives a first power signal that is output from the first piezoelectric element based on both impact of the golf club with an object and vibrations, the first signal divider having a first output and a second output, wherein the first output is coupled to signal processing circuitry and the second output is coupled to an energy storage assembly that includes a battery; and
a processor that is configured to dynamically adjust a ratio of a first amount of the first power signal the first signal divider sends through the first output to the signal processing circuitry versus a second amount of the first power signal the first signal divider sends through the second output to the energy storage assembly, wherein the processor is further configured to perform impact analysis of the impact of the golf club with the object.

US Pat. No. 10,112,073

GAMERS MULTI-DIGIT DEVICE FOR HAND EXERCISES

HARRISON LEGACY 301, LLC,...

1. A multi-digit hand exercise device comprising:a main body with three rings coupled at rest in a triangular configuration by a plurality of bridges, wherein a first one of three rings is located at one end of a base of the triangular main body, a second one of the three rings is located at an opposing end of the base of the triangular main body, and a third one of the three rings is located at an apex of the triangular main body, wherein the first ring is configured for a person's thumb and the second and third rings are configured for two fingers, wherein each ring's inside surface comprises a plurality of elevated and flexible ridges that run depthwise and configured for massaging the finger or thumb;
a first bridge of the plurality of bridges connecting the first one of the three rings to the third one of the three rings;
a second bridge of the plurality of bridges connecting the second one of the three rings to the third one of the three rings; and
a third bridge of the plurality of bridges connecting the second one of the three rings to the first one of the three rings, wherein the third bridge is greater in thickness than the first and second bridges for greater stiffness, wherein the plurality of bridges and an inside facing perimeter of each of the rings between corresponding bridges together define a substantially triangular center hole when at rest and that is configured to accommodate multiple digits of the person's hand.

US Pat. No. 10,112,072

DYNAMIC STRETCHING, STRENGTHENING AND STABILIZATION DEVICE FOR POSTURAL CORRECTION AND RETRAINING

POSTURE PERFECTOR LLC, A...

1. A dynamic stretching, strengthening and stabilization device comprising:a central member having a width and a height, with the height being greater than the width;
a resistance tube first loop on a first side of the central member and a resistance tube second loop on a second side of the central member;
a flexible handle disposed on each loop;wherein the user:can grip the handles and pull in opposing directions to actively engage the resistance tubes in a stretching/strengthening mode; and
can position each of the loops over one of the user's arms so that the central member is positioned in a region of the user's back with the height extending in a vertical direction along the user's back and with the width extending in a horizontal direction from side to side across the user's back, and the handles are positioned to cushion where the loop engages the user's pectoral or underarm region in a stabilization mode; the loops being sized to fit snugly on the user and provide passive resistance against forward shoulder curvature in the stabilization mode.

US Pat. No. 10,112,071

REAR HANDLEBAR ASSEMBLY FOR A STATIONARY BIKE

1. A rear handlebar assembly in combination with a seat and a supporting member of a stationary bike, comprising:a seat of a stationary bike for supporting a rider thereon;
a supporting member for supporting the seat of the stationary bike;
a joining member including a vertical bore and a horizontal bore, the vertical bore receiving therein the supporting member to connect the joining member to the seat;
a clasp for holding the joining member against the supporting member;
a crossbar forming a rear handlebar adapted to support the hands of a rider in an upright riding position; and
a rearwardly extending member connecting the joining member to the crossbar;
wherein the joining member includes a pair of serrated surfaces and the clasp includes a pair of clasping members with each clasping member having a mating surface to engage one of the serrated surfaces to hold the joining member in place.

US Pat. No. 10,112,070

BALANCE TRAINING DEVICE FOR YOUNG CHILDREN

I Shyang Enterprise Co., ...

1. A balance training device for young children comprising:a footplate mounted with at least one assembly hole formed on a bottom surface thereof, a recess portion is formed on a bottom surface of the footplate; a plurality of longitudinal ribs and a plurality of transverse ribs are disposed on the recess portion at intervals; the assembly hole is arranged at an intersection area of one longitudinal rib and one transverse rib;
at least one support disposed under the footplate and having an assembly pin projecting from a top end thereof;
a fixing block set on each of two sides of the assembly pin on the top end of the support, each fixing block being disposed with a mounting groove for mounting and fixing a transverse rib located on each of two sides of the assembly hole on the bottom surface of the footplate; and
at least one base arranged under the support and disposed with a positioning slot on a top end thereof;
wherein the assembly pin is able to be connected to the assembly hole of the footplate; a bottom end of the support is mounted in the positioning slot of the base; and the support and the positioning slot of the base are connected in a clearance fit.

US Pat. No. 10,112,069

CORE MUSCLE THERAPY APPARATUS

1. A core muscle therapy apparatus, comprising:a base comprising a first base frame and a second base frame;
a cage assembly positioned substantially between the first base frame and the second base frame, the cage assembly having an upper cage frame member, a lower cage frame member, a first side cage frame member, and a second side cage frame member, wherein the first side cage frame member is pivotally connected to the first base frame at a first connection point and the second side cage frame member is pivotally connected to the second base frame at a second connection point, wherein a first axis of rotation is defined coaxial with a line formed between the first and second connection points, and wherein the cage assembly is configured to rotate about the first axis of rotation;
a seat assembly rotationally connected to the upper cage frame member at a third connection point and the lower cage frame member at a fourth connection point, the seat assembly being configured to rotate about a second axis of rotation that is substantially perpendicular to the first axis of rotation, wherein the seat assembly comprises a seat configured to seat a user therein, and
a pneumatic piston operationally engaged with a portion of the cage assembly via a rocker arm, the pneumatic piston positioned such that operation of the pneumatic piston causes the rocker arm to rotate the cage assembly at least partially about the first axis;
wherein rotation of the cage assembly about the first axis of rotation moves the seat assembly from a substantially upright position to a predetermined reclined position angle, and
wherein rotation of the seat assembly about the second axis of rotation rotates the user in the seat about the second axis of rotation at the predetermined reclined position angle.

US Pat. No. 10,112,068

EXERCISE APPARATUS AND METHOD

1. An exercise apparatus, comprising:a flexible elastic portion comprised of at least one elastic member of elongate dimension; and
a pair of handles being attached to said elastic portion in spaced apart positions therealong in an elongated direction thereof, each of said handles having a handle grip portion extending along a handle grip axis and including a structural configuration which allows the alternate orientation of said elastic portion in a first attached position in which said elongated direction extends from said handle grip portion crosswise to said handle grip axis and a second attached position in which said elongated direction extends from said handle grip portion codirectional with said handle grip axis in order to achieve a configuration respectively suited to aerobic activity, or to resistance training and stretching.

US Pat. No. 10,112,067

EXERCISE MACHINE WITH MULTI-FUNCTION WHEEL BRAKE ACTUATOR AND OVER CENTER LOCKING MECHANISM

Foundation Fitness, LLC, ...

1. An exercise machine comprising:a frame supporting a rotating member;
a resistance element moveable between at least a first resistance element position and a second resistance element position, the first resistance element position associated with a first resistance on the rotating member and the second resistance element position associated with a second resistance on the rotating member, the second resistance being different than the first resistance; and
a resistance adjustment assembly comprising:
a shaft coupled to the resistance element and translatable relative to the frame between a first shaft position and a second shaft position, the first shaft position corresponding to the first resistance element position and the second shaft position corresponding to the second resistance element position; and
a lever assembly operably coupled with the shaft, the lever assembly independently rotatable from the shaft between a first lever position and a second lever position to translate the shaft between the first shaft position and the second shaft position.

US Pat. No. 10,112,066

OCCUPATIONAL THERAPY DEVICE

AJL LLC, Byron Center, M...

1. A mirror therapy device comprising:a mirror having a reflective surface;
a first functional component movably disposed on a first side of said mirror, said reflective surface providing a reflected image of said first functional component;
a second functional component movably disposed on a second side of said mirror, said second functional component being hidden by said mirror; and
a linkage operatively joining said first functional component to said second functional component, said linkage configured to cause said second functional component to move in a manner substantially consistent with said reflected image of said first functional component.

US Pat. No. 10,112,065

METHOD FOR INSTALLING A FIRESTOP DEVICE OR INSULATION HAVING FIRESTOP PROPERTIES AS WELL AS A FIRESTOP MODULE

Hilti Aktiengesellschaft,...

1. A method for installing a firestop device or insulation on a line or pipe, comprising:placing the firestop device or the insulation completely around the line or pipe in the circumferential direction; and
wrapping a flexible adhesive tape containing heat-resistant fibers in a lengthwise direction of the tape in the circumferential direction of the line or pipe completely around the firestop device or the insulation.

US Pat. No. 10,112,064

HARNESS

ZEDEL, Crolles (FR)

1. A harness comprising a belt, a pair of thigh straps and a ventral suspension point, the ventral suspension point comprising:a connector positioned on the belt, the connector comprising
a connecting ring fitted to be rotatable with respect to the belt around an axis of rotation, the connecting ring being a closed ring defining a first area, and
a rod having a longitudinal axis that forms the axis of rotation of the connector, the rod fixing the connector to the belt, the rod comprising
a first end and a second end opposite the first end, the first end and the second end being disposed along the axis of rotation of the connector, and
a first attachment opening and a second attachment opening designed to cooperate for fixing an external device, the first attachment opening and the second attachment opening being defined in the rod outside the first area so that the axis of rotation of the connector passes through the first attachment opening and the second attachment opening.

US Pat. No. 10,112,063

EMERGENCY ESCAPE SLIDE INCORPORATED INTO EXIT

AltEvac, LLC, Boca Raton...

1. An emergency escape mechanism for a building having a floor, comprising:an exit door located within a doorway on an exterior of the building, said doorway having an exterior side on the exterior of the building, and also having an interior side;
an inflatable emergency escape slide having a portion of a first end coupled to a lower portion of the doorway and a second end resting against an outer surface of the interior side of said exit door, said second end configured to drop out of said doorway when said exit door is opened;
an alarm box located proximate said exit door, said alarm box further including an alarm switch and wherein said alarm switch is further connected to a locking bar engaging said exit door;
an inertially-activated switch positioned on said first end;
a gas release device in gas communication with said inflatable emergency escape slide;
a girt bar anchored in the floor of the building in the lower portion of the interior side of the doorway; and
escape slide support straps attached to said girt bar and to said portion of said first end of said emergency escape slide, said alarm switch being coupled to said locking bar and being configured to be activated to cause said locking bar to cause said exit door to open, whereupon said first and second ends of said emergency escape slide go into motion as said second end automatically drops out of said doorway to a position outside the building, said inertially-activated switch automatically operating in response to said motion to generate an electrical signal, said gas release device being responsive to said electrical signal provided by said inertially-activated switch to inflate said emergency escape slide in automatic response to said electrical signal.

US Pat. No. 10,112,062

AUTO BRAKE HAND DESCENT CONTROL DEVICE

Fire Innovations LLC, Pe...

1. A descent device, comprising:a body having an outer side and an inner side an upper side a lower side, a right side, and a left side;
an elongate handle integrally affixed to and extending from an inner portion of said upper side of said body, said handle and said body having a common longitudinal axis;
an attachment lug disposed on an outer portion of said body for attachment to a rope or lanyard;
a payout hole disposed through said body from said inner side to said outer side and having a central axis on and normal to said common longitudinal axis;
an anchor hole disposed above said payout hole through said body from said inner side to said outer side and having a central axis on and normal to said common longitudinal axis and parallel to the central axis of said payout hole, and wherein a portion of said anchor hole and a portion of said payout hole are conjoined;
right and left holes disposed through said body from said inner side to said outer side, each having a central axis normal to said common longitudinal axis, and configured such that a line drawn between said central axes of said right and left holes is normal to said longitudinal axis; and
shallow channels on said inner side of said body disposed between each of said left and right holes and said anchor hole to accommodate and constrain a rope or tubular webbing segment bent proud between one or the other of said side holes and said anchor hole;
wherein said payout hole, said anchor hole, and said right and left holes are configured for selective payout and locking of the rope or tubular webbing passed through said right hole, said left hole, and said anchor hole in a predetermined threading pattern.

US Pat. No. 10,112,060

ION BEAM EXTRACTION APPARATUS AND METHOD OF USE THEREOF

1. A method for imaging a tumor, comprising the steps of:providing ions with an ion source, said ion source comprising:
an electron resonance cyclotron ion source, said electron resonance cyclotron generating the ions, the ions comprising at least one of:
cations, said cations comprising at least one of:
protons;
C4+; and
C6+; and
anions;
and
imaging a tumor with a first two-dimensional imaging system using the ions extracted from said ion source; and
imaging the tumor with a second two-dimensional imaging system using X-rays, said steps of imaging the tumor with said first two-dimensional imaging system and imaging the tumor with said second two-dimensional imaging system overlapping in time.

US Pat. No. 10,112,058

SMART LASER HAIR GROWTH HELMET

Theradome, Inc., Pleasan...

1. A photo-bio-stimulation device in the form of a helmet that promotes therapeutic hair growth, comprising:a plurality of power-controlled near infrared (NIR) laser diode arrays mounted on a concave single flexible printed circuit inside a plastic helmet that generally direct a monochromatic and coherent therapeutic light across the scalp of a user wearing it;
wherein, a number of petal shapes are cut on two side edges of the flexible printed circuit and that are cupped and attached inside the plastic helmet;
a plurality of cooling air vents fenestrated through the plastic helmet that allow air heated during operation to pass outside for cooling;
a controller that operates the plurality of power-controlled near infrared (NIR) laser diode arrays according to predefined therapeutic profiles and sessions, and that maintains an operational status and log;
a proximity sensor that detects the presence of a user scalp and that triggers the controller to shut off battery power to the plurality of power-controlled near infrared (NIR) laser diode arrays if the user scalp is not then detected as being proximate;
at least one temperature sensor that triggers the controller to shut off battery power to the plurality of power-controlled near infrared (NIR) laser diode arrays if a predefined temperature is exceeded;
a speech synthesizer and a loudspeaker connected to the controller and that speak instructions and the operational status of the device to the user in a spoken language; and
a wireless transceiver capable of Internet communication with a centralized server, and that is connected to exchange status and operational data with the controller.

US Pat. No. 10,112,056

OPTIMISING CURRENT DIRECTION AND INTENSITY OF TRANSCRANIAL MAGNETIC STIMULATION

Monash University, (AU)

1. A method of optimising transcranial magnetic stimulation comprising:positioning a coil having a coil centre at a location relative to a target cortical region of a patient, wherein the target cortical region is a region outside of the motor cortex;
applying an electrical signal to the coil to generate one or more magnetic field pulses for transcranial magnetic stimulation of the target cortical region of the patient, wherein the transcranial magnetic stimulation has stimulation parameters including orientation of the coil relative to the patient and intensity of the magnetic stimulation;
while maintaining the coil centre at the location, varying at least the orientation of the coil relative to the patient;
at different orientations of the coil relative to the patient, monitoring neuron activation at the target cortical region using near infra-red spectroscopy (NIRS); and
based on information obtained during the monitoring, determining one or more optimal coil orientations for the transcranial magnetic stimulation.

US Pat. No. 10,112,054

DEFIBRILLATOR

Revive Solutions, Inc., ...

1. A defibrillator unit comprising:a connector suitable for facilitating connecting the defibrillator unit to a mobile communication device to facilitate receiving power from the mobile communication device;
electrocardiography circuitry for detecting electrical activity of a heart of a patient;
a capacitor unit capable of temporarily storing and discharging sufficient energy to deliver a defibrillation shock to a patient;
shock delivery circuitry for discharging the a capacitor unit to deliver the defibrillation shock;
a charging circuit that controls the transfer of energy from the mobile communication device to the capacitor unit to facilitate charging the capacitor unit to a level suitable to facilitate the delivery of the defibrillation shock to the patient, wherein the defibrillator unit is configured to automatically begin charging the capacitor unit when the defibrillator unit is initially connected to the mobile communication device; and
a defibrillator controller configured to determine whether a patient has a shockable heart rhythm based on the electrical activity of the heart of the patient detected by the electrocardiography circuitry, control the charging circuit to thereby control the charging of the capacitor unit, and control the shock delivery circuitry to thereby control the delivery of the defibrillation shock when it is determined that the patient has a shockable heart rhythm, wherein the determination of whether the patient has a shockable heart rhythm is independently made by the defibrillator controller without the receipt of any shock commands or analysis of the patient from the mobile communication device.

US Pat. No. 10,112,053

IMPLANTABLE MEDICAL DEVICES WITH HEADER STRUCTURES INCLUDING CONDUCTIVE PATHS THAT FACILITATE THE INTERCONNECTION OF FEEDTHROUGH CONDUCTORS TO ELECTRICAL CONNECTORS

MEDTRONIC, INC., Minneap...

1. An implantable medical device, comprising:a housing;
circuitry within the housing, the circuitry comprising a plurality of feedthrough conductors that exit the housing;
a header structure having a plurality of holes passing from a first side of the header structure to a second side of the header structure;
a plurality of conductive paths, with a conductive path of the plurality passing through a corresponding hole of the plurality of holes, the conductive path having a first end present on the first side of the header structure and a second end present on the second side of the header structure, the second end being electrically coupled to a corresponding feedthrough conductor of the plurality of feedthrough conductors;
a plurality of electrical connectors present within an interior of the header structure, wherein the header structure comprises a header body with a first cavity exposed to the first side of the header structure and a second cavity exposed to the second side of the header structure, with a first set of the electrical connectors of the plurality of electrical connectors being present within the first cavity and with a second set of the electrical connectors of the plurality of electrical connectors being present within the second cavity, and wherein the first end of each conductive path of the plurality of conductive paths is electrically coupled to a corresponding electrical connector of the plurality of electrical connectors within the header structure.

US Pat. No. 10,112,052

CONTROL AND/OR QUANTIFICATION OF TARGET STIMULATION VOLUME OVERLAP AND INTERFACE THEREFOR

Boston Scientific Neuromo...

1. A computer-implemented method; comprising:determining, by a computer processor, a volume of activation (VOA) of tissue estimated to be activated by stimulation provided according to a set of stimulation parameters;
generating and outputting, by the processor, a first score for the VOA based on a) an amount by which the VOA overlaps another obtained volume and b) at least one of the following:
1) a size of an area formed by a combination of the VOA and the other obtained volume,
2) a size of a predetermined area excluding both the VOA and the other obtained volume, or
3) an amount of the VOA that does not overlap the other obtained volume; and
upon manipulation of a user-manipulable control, outputting a set of stimulation parameters corresponding to the VOA to initiate stimulation of patient tissue using a leadwire implanted in the patient tissue.

US Pat. No. 10,112,050

ELECTRODE SELECTION FOR SUB-THRESHOLD MODULATION THERAPY

Boston Scientific Neuromo...

1. A method of neuromodulation, the method comprising:determining a ratio between an anodic perception threshold and a cathodic perception threshold for each of a plurality of electrode sets;
selecting an effective electrode set from the plurality of electrode sets based on the ratios; and
providing sub-threshold modulation therapy to a patient, including delivering sub-threshold electrical energy from the effective electrode set.

US Pat. No. 10,112,048

STIMULATION DEVICES AND METHODS FOR TREATING DRY EYE

Oculeve, Inc., South San...

1. A method for treating dry eye in a patient in need thereof, comprising:contacting nasal mucosa of the patient with a first electrode; and
delivering current from the first electrode through tissue of the patient to a return contact,
wherein the first electrode is located on a nasal insertion prong of a stimulator probe of a stimulator, and the return contact is located on a stimulator body of the stimulator, and wherein the stimulator probe is reversibly attachable to the stimulator body.

US Pat. No. 10,112,047

COCHLEAR IMPLANT

The Regents of the Univer...

1. A device for implantation into a scalia tympani of a cochlea that is connected to an auditory nerve with the cochlea having a plane of curvature and including cochlear fluid, said device comprising:a plurality of blocks;
a plurality of compliant elements interconnecting said plurality of blocks with one of said plurality of compliant elements disposed between each pair of adjacent blocks, said plurality of compliant elements for imparting flexibility to said device in the plane of curvature of the cochlea and for imparting stiffness to said device out of the plane of curvature of the cochlea;
a processing unit for processing sound into an electrical signal;
a plurality of electrodes with at least one of said electrodes disposed on each of said blocks, said plurality of electrodes for transmitting the electrical signal to the auditory nerve; and
a plurality of communication lines for transmitting the electrical signal through said device with one of said plurality of communication lines disposed between each of said pair of adjacent blocks and adjacent said compliant element.

US Pat. No. 10,112,046

BIONIC COCHLEA HAVING PIEZOELECTRIC NANOWIRES OF AN INTERNAL MEMBRANE

The United States of Amer...

1. A bionic cochlea comprising:a fluid filled vessel comprising walls;
a flexible first window disposed in one of the walls, the first window having a thickness and being comprised of a material selected so that the first window will flex when exposed to an acoustic pulse to produce an acoustic pressure pulse in the fluid inside the vessel;
a flexible membrane disposed within the fluid filled vessel;
a plurality of piezoelectric nanowires disposed within the fluid filled vessel and extending from at least one side of the flexible membrane, each of the nanowires having a first end fixed to the flexible membrane and an unattached second end extending into the interior of the vessel, wherein each of the nanowires has a length selected to vibrate in response to at least one predetermined wavelength in the acoustic pressure pulse, thereby producing an electrical signal; and
at least one electrical wire in communication with the plurality of piezoelectric nanowires and running along the flexible membrane to receive the produced electrical signals, the electrical wire passing through the walls of the vessel.

US Pat. No. 10,112,045

IMPLANTABLE MEDICAL DEVICE FIXATION

Medtronic, Inc., Minneap...

1. An assembly comprising:an implantable medical device including a conductive housing; and
a fixation element assembly fixedly attached to the implantable medical device near a distal end of the conductive housing, wherein the fixation element assembly includes a set of active fixation tines and an insulator to electrically isolate the set of active fixation tines from the conductive housing of the implantable medical device,
wherein the active fixation tines in the set are deployable from a spring-loaded position in which distal ends of the active fixation tines point away from the implantable medical device to a hooked position in which the active fixation tines bend back towards the implantable medical device,
wherein the active fixation tines are configured to secure the implantable medical device to a patient tissue when deployed while the distal ends of the active fixation tines are positioned adjacent to the patient tissue,
wherein the active fixation tines are in a circular arrangement about a base with proximal ends of the active fixation tines secured to the base, and
wherein the insulator includes a header body with notches to receive the active fixation tines and a header cap that combines with the header body to encompass the base such that the active fixation tines are fixedly attached to the implantable medical device at a location near the distal end of the conductive housing both when the active fixation tines are in the spring-loaded position and when the active fixation tines are in the hooked position.

US Pat. No. 10,112,041

IMPLANTABLE CONNECTOR CLEANING SYSTEM

Cochlear Limited, Macqua...

1. A system, comprising:an implantable connector including first and second detachable mating parts configured:
to be implantable in living tissue;
to terminate at least a first segment of a cable; and
to have first and second interfacing surfaces, respectively; and
a cleaning structure configured to clean the first and second interfacing surfaces as the first and second mating parts are being engaged.

US Pat. No. 10,112,040

TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION USING NOVEL UNBALANCED BIPHASIC WAVEFORM AND NOVEL ELECTRODE ARRANGEMENT

Neurometrix, Inc., Walth...

1. Apparatus for providing transcutaneous electrical nerve stimulation to a user, said apparatus comprising:a stimulation unit for electrically stimulating nerves using asymmetric biphasic electrical pulses, wherein during the first phase and the second phase of an asymmetric biphasic electrical pulse, said stimulation unit generates a voltage at an anode that is higher than a voltage at a cathode so as to allow current to flow from the anode to the cathode, and wherein said stimulation unit delivers a larger amount of electrical charge in the second phase of the asymmetric biphasic electrical pulse than the amount of electrical charge delivered in the first phase of the asymmetric biphasic electrical pulse using the same anode voltage setting in both phases of the asymmetric biphasic electrical pulse to deliver the same current intensity by taking advantage of the electrical charge accumulated during the first phase of the asymmetric biphasic electrical pulse;
a control unit for controlling the electrical stimulation delivered by said stimulation unit; and
an electrode array connectable to said stimulation unit, said electrode array comprising a substrate and at least first and second electrodes, the at least first and second electrodes being mounted to said substrate with a predetermined arrangement, so that when said substrate is placed on one limb of the user, said first electrode overlays a first nerve on the limb of user but not a second nerve on the limb of the user and said second electrode overlays the second nerve on the limb of the user but not the first nerve on the limb of the user;
whereby, the first electrode activates the first nerve during the first phase of the asymmetric biphasic electrical pulse and the second electrode activates the second nerve during the second phase of the asymmetric biphasic electrical pulse.

US Pat. No. 10,112,039

CLOSED MALE LUER CONNECTOR

ELCAM MEDICAL AGRICULTURA...

1. A fluid flow connector comprising:a housing assembly having a first end and a second end arranged along a common longitudinal axis;
a forward resilient member disposed within said housing assembly, said forward resilient member having a forward end disposed alongside said first end, said forward end defining a selectably closable slit;
a rigid fluid flow conduit member at least partially disposed within said forward resilient member rearwardly of said forward end; and
a rearward resilient displacement biasing element associated with said rigid fluid flow conduit member and with said housing assembly;
said rigid fluid flow conduit member being positionable in a forward position, causing said slit to be closed,
said rigid fluid flow conduit member being positionable in a rearward position, causing said slit to be open, and
wherein displacement of said rigid fluid flow conduit member from said rearward position to said forward position causes a first volume, adjacent to and rearward of said forward end of said forward resilient member, to decrease by a first amount and a second volume, rearwardly of said rearward resilient displacement biasing element and in communication with said rigid fluid flow conduit member, to increase by a second amount, greater than said first amount.

US Pat. No. 10,112,038

UMBRELLA CHECK VALVE WITH REDUCED HEMOLYSIS

VERNAY LABORATORIES, INC....

1. A check valve assembly comprising:an elongated valve body having an inlet port, an outlet port, and an internal channel communicating between said inlet port and said outlet port, each disposed about and generally aligned with a central longitudinal axis of the valve body;
said inlet port including an umbrella check valve disposed at an entrance to said internal channel and configured to obstruct reverse flow from said internal channel into said inlet port;
a distance along said central longitudinal axis from the entrance to said internal channel toward the outlet port being denoted as x, and the a radial separation of an interior wall of the internal channel from the central longitudinal axis being denoted as r, with r varying with x according to:
r?=8+SQRT(20.25?(x?4.5)?2) for 08;  Equation (1)
r?=0.0068*x?3?0.2242*x?2+1.5392*x+9.6571 for 4.5 and
r(x)=r?(x)±2.0, where ± denotes a tolerance,  Equation (3)with the separation r defining an essentially continuously curved interior surface.

US Pat. No. 10,112,037

BLOOD CIRCUIT CONNECTOR

NIPRO CORPORATION, Osaka...

1. A blood circuit connector comprising;a main body having a cylindrical shape, the main body having a through hole provided therein to have one end provided with a first opening end and the other end provided with a second opening end;
a plug having a bottomed cylindrical shape and detachably attached to the first opening end; and
a connection part having flexibility and configured to connect the main body and the plug,
the plug including a side wall loosely fitted to an outer circumferential surface of the first opening end and a bottom facing the first opening end in an extending direction of an axis line of the main body in an attached state where the plug is attached to the first opening end,
the connection part including a first fixed end connected to the side wall of the plug, a second fixed end connected to an outer circumferential surface of the main body, and a curved part located between the first fixed end and the second fixed end and expanding in a direction away from the main body, and
in the attached state, the curved part being pushed in a direction approaching the outer circumferential surface of the main body such that the curved part extends, to cancel a loosely fitted state between the side wall of the plug and the outer circumferential surface of the first opening end, so as to remove the plug from the first opening end.

US Pat. No. 10,112,036

ENDOVASCULAR CEREBROSPINAL FLUID SHUNT

Tufts Medical Center, Inc...

1. A method for draining cerebrospinal fluid from a patient's subarachnoid space, the method comprising the steps of:providing an implantable shunt having opposed first and second ends, a one-way valve located at the first end of the shunt, and a tip disposed at the second end, said tip being constructed to penetrate a sinus wall of the patient, wherein the first and second ends are in fluid communication to enable the cerebrospinal fluid (CSF) to be drained through the tip and out through the valve;
endovascularly delivering the shunt to the sinus wall;
penetrating the sinus wall and implanting the second end of the shunt in a CSF space of the patient; and
draining cerebrospinal fluid from the patient.

US Pat. No. 10,112,035

CATHETER WITH VESSEL LINING AND METHODS FOR USING SAME

Cruzar Medsystems, Inc., ...

1. A method of providing access across a site of obstruction, the method comprising:positioning an inverted, distal portion of a sleeve adjacent to a site of obstruction;
inflating a balloon from a position in which a length of the balloon is situated entirely within a length of a remaining portion of the sleeve such that the balloon moves the distal portion from an inverted position to an everted position so the distal portion extends across the site of obstruction; and
deflating the balloon after eversion so as to provide access across the site of obstruction via a pathway through the sleeve, the pathway extending alongside the deflated balloon, across a juncture between the distal portion and the remaining portion of the sleeve and through a distal end of the distal portion.

US Pat. No. 10,112,032

MEDICAL TIMING DEVICE AND METHOD HAVING SINGLE ACTION TRIGGERING FOR ACTIVATION AND LOCK CONDITIONS

Harris Skeele Corporation...

1. A medical timing device comprising:a body comprising a first lock member, wherein the body defines an article-receiving space configured to receive an article portion of a medical article;
a timer coupled to the body, wherein the timer is configured to indicate an in-use time of the medical article;
a triggering element; and
a retainer coupled to the triggering element, the retainer being moveably coupled to the body, wherein the retainer is configured to be moved from an open position providing access to the article-receiving space to a closed position blocking at least part of the article-receiving space, wherein the retainer comprises a second lock member;
wherein the retainer is configured so that, in response to a single action of moving the retainer from the open position to the closed position, the triggering element:
activates the timer to initiate a process to indicate the in-use time of the medical article; and
causes the second lock member to become locked together with the first lock member to lock the retainer in the closed position after the article portion has been inserted in the article-receiving space,
wherein the locked retainer is configured to keep the medical timing device coupled to the article portion even after the timer indicates that the medical article has been used for more than a designated usage period,
wherein the locked retainer is configured to prevent the medical timing device from being removed from the article portion without use of a tool or partial destruction of the article portion or the medical timing device, thereby inhibiting wrongful removal of the medical timing device from the article portion.

US Pat. No. 10,112,031

CATHETER PACKAGED INSIDE OF A HANDLE ATTACHED TO A CONTAINER

1. A catheter assembly comprising:a catheter packaged inside of a handle that is attached to a container;
wherein the catheter has a proximal end portion that is insertable into a urethra and a distal end portion that includes a valve, where the valve includes a valve seat formed inside of the distal end portion of the catheter and a protrusion is located inside the handle and movable relative to the valve;
wherein the handle has a cavity extending between a proximal end portion and a distal end portion of the handle, where the distal end portion of the handle is engaged with the valve seat of the catheter to close the valve of the catheter, and where the container is removable from the proximal end portion of the handle to disengage the distal end portion of the handle from the valve seat of the catheter and to expose the proximal end portion of the catheter; and
wherein a flange is formed on an interior surface of the cavity of the handle, and the flange is sized to engage with the protrusion coupled to the exterior of the distal end portion of the catheter;
wherein the valve of the catheter opens when the protrusion of the catheter contacts the flange.

US Pat. No. 10,112,029

BONE CONDUCTION APPARATUS AND MULTI-SENSORY BRAIN INTEGRATION METHOD

INTEGRATED LISTENING SYST...

1. A method for the enhancement of sensory processing and sensory integration of a subject within a setting including a plurality of subjects, comprising:evaluating the subject to determine one or more deficiencies within one or more developmental phases;
developing a therapeutic regimen to remedy the determined deficiencies;
filtering a composition, comprising music and sounds, to change the relative amplitude of a frequency range within the composition and generating two output signals;
delivering said filtered composition to the plurality of subjects through air conduction audio room speakers based on a first output signal of the two output signals;
transmitting wirelessly, to combination air conduction/bone conduction headphones of the subject, a second output signal derived from said filtered composition; and
directing said subject to perform one or more activities from one or more groups of activities associated with said frequency range, each activity directed toward the one or more determined deficiencies,
wherein an amplitude of the first output signal and the second output signal are independently variable, and
wherein the combination air conduction/bone conduction headphones include controls such that an amplitude of the second output signal driving the air conduction portion of the headphones and the second output signal driving the bone conduction portion of the headphones are independently variable.

US Pat. No. 10,112,028

HUMIDIFICATION CHAMBER FOR A RESPIRATORY ASSISTANCE APPARATUS

1. A humidification chamber for humidifying gases, comprising:a water tub that is configured to receive a volume of water;
a lid hingedly coupled to the water tub for enclosing the water tub to define the interior volume of the humidification chamber and which is movable between a closed position in which the water tub is closed by the lid and an open position in which the water tub is open,
wherein a seal is located between the lid and the water tub, the seal engaging a perimeter of the water tub;
wherein the lid is formed from plastic, and
wherein the water tub comprises a base, a perimeter wall that extends upwardly from the base, and a metallic heater plate, an underside of the base comprising a rigid plastic portion and an exposed metallic portion of the metallic heater plate;
one or more clips for securing the lid in the closed position;
a lateral gases inlet for receiving a flow of gases into the interior volume of the humidification chamber, wherein the gases inlet is formed in the lid, the gases inlet having an associated inlet conduit extending into the interior volume of the humidification chamber; and
a lateral gases outlet through which a humidified flow of gases may exit the interior volume of the humidification chamber, wherein the gases outlet is formed in the lid, the gases outlet having an associated outlet conduit extending into the interior volume of the humidification chamber.

US Pat. No. 10,112,026

RESPIRATORY MASK

LOEWENSTEIN MEDICAL TECHN...

1. A respiratory mask comprising a mask body and an articulated connector that can be connected with a respiratory hose, wherein at least one exhalation gap is located in a vicinity of the mask body and a mechanical coding system is provided for joining the mask body and the connector.

US Pat. No. 10,112,025

SELF-CONTAINED, INTERMITTENT POSITIVE AIRWAY PRESSURE SYSTEMS AND METHODS FOR TREATING SLEEP APNEA, SNORING, AND OTHER RESPIRATORY DISORDERS

Hancock Medical, Inc., M...

1. A system to aid respiration of an individual, comprising:a mask comprising a first mask inlet valve and a mask outlet valve, wherein the first mask inlet valve is configured for one-way flow into the mask;
a self-contained airflow manifold comprising an air inlet valve and a positive pressure source configured to be worn by the individual and comprising a controller configured to intermittently operate the positive pressure source to increase positive air pressure in the mask to resist tissue collapse in the upper airway during only a portion of a respiratory cycle less than the entire respiratory cycle;
an air path connecting the airflow manifold to the mask;
wherein the positive pressure source is configured to supply positive air pressure from the air inlet valve to the first mask inlet valve.

US Pat. No. 10,112,024

MEDICAL TUBE APPARATUS

Monitoring For Life LLC, ...

1. An endotracheal tube apparatus having a proximal end and a distal end, and further comprising:an endotracheal tube having a proximal end and a distal end;
a hub connection fitting connected to the endotracheal tube, the hub connection fitting disposed adjacent the proximal end of the endotracheal tube proximal to the proximal end of the endotracheal tube;
the endotracheal tube configured to be inserted into a trachea of a human body;
a ventilation passageway disposed in the hub connection fitting and along a length of the endotracheal tube;
a cuff inflation passageway disposed in the hub connection fitting and the endotracheal tube;
a light emitting device comprising a light source and a tubular light guide, the light source and the tubular light guide arranged such that light, when emitted from the light source, is transmitted along a longitudinal axis of the tubular light guide;
the light source disposed in the hub connection fitting; and
the tubular light guide disposed in the endotracheal tube within the cuff inflation passageway.

US Pat. No. 10,112,023

BREATHING-GAS DELIVERY AND SHARING SYSTEM AND METHOD

The Research Foundation f...

1. A patient respiration isolation device, comprising:a movable partition having an actuating side on a first side of the movable partition, and a patient side on a second side of the movable partition;
a housing disposed about the movable partition, the housing having an ventilator orifice adaptable to be in pneumatic communication with a ventilator;
an inlet pressure regulator in fluid communication with the actuating side of the movable partition; and
an exhaust pressure regulator capable of controlling a positive-end-of-expiration pressure (“PEEP”) in fluid communication with the patient side of the movable partition;
further comprising a CO2 scrubber in fluid communication with the patient side of the movable partition.

US Pat. No. 10,112,022

METHOD FOR DETECTING AN INSPIRATORY FLOW LIMITATION DURING SLEEP-DISORDERED BREATHING

DeVilbiss Healthcare LLC,...

1. A breathing therapy machine having an optimized auto-adjust capability comprising:a. a blower, for delivering air to a user of said device at a pressure;
b. a processor, for controlling said blower;
c. non-volatile memory, accessible by said processor, said non-volatile memory including operational programming;
d. an airflow sensor, electrically connected to said processor for gathering data regarding a volume of airflow to said patient, said operational programming producing an airflow waveform from said gathered data; and
e. a flow limitation detection module, stored in said non-volatile memory as part of said operational programming, wherein said flow limitation detection module is configured to detect a flow limitation condition by:
grouping data points sampled from an inspiration portion of the airflow waveform into a plurality of bins;
for each bin, calculating an average slope value using the data points within the bin;
computing a plurality of variance values, wherein each variance value is computed by defining a moving window that utilizes average slope values calculated for at least three of the bins; and
selecting and analyzing a lowest variance value of the plurality of variance values to determine if the flow limitation condition exists;
wherein said pressure of said air is altered based on detection of the flow limitation condition.

US Pat. No. 10,112,020

AIRFLOW ADAPTOR FOR A BREATH-ACTUATED DRY POWDER INHALER

Norton Healthcare Limited...

1. A method for de-agglomerating dry powder in a breath-actuated dry powder inhaler, comprising:directing a first breath-actuated airflow for entraining the dry powder from a dry powder inhaler into a first end of a swirl chamber extending along a longitudinal axis from the first end of the swirl chamber to a second end of the swirl chamber, the first airflow directed in a longitudinal direction;
directing a second breath-actuated airflow in a substantially transverse direction into the first end of the swirl chamber such that the first and the second breath-actuated airflows collide and substantially combine;
directing a portion of the combined airflows in a spiral path towards the second end of the swirl chamber;
directing all the combined airflows and any dry powder entrained therein through an outlet port in the second end of the swirl chamber and into a proximal end of a conduit of an airflow adaptor that is connected to the outlet port of the swirl chamber;
delivering all the combined airflows and any dry powder entrained therein through the conduit and to a user of the dry powder inhaler through a first outlet port defined at a distal end of the conduit that is located on a flange of the airflow adaptor;
directing a third breath-actuated airflow to the airflow adaptor having by-passed the swirl chamber; and
delivering the third breath-actuated airflow to the user through at least one secondary outlet port defined on the flange of the airflow adaptor having by-passed the conduit, wherein the third breath actuated airflow exits the dry powder inhaler as it passes through the at least one secondary outlet port, and combines with the first and second breath-actuated airflows only after the first and second breath-actuated airflows have left the airflow adaptor.

US Pat. No. 10,112,019

DRY POWDER INHALER

1. An inhaler (I), comprising:an inlet into which air is drawn,
an outlet through which air exits,
a pharmaceutical medicament formed of a loose, dry powder formulation for suspension in the air and being entrained by an air flow of the air generated passively, by which a patient draws the air via inhalation to create the air flow and a resultant aerosol,
a chamber (3, 13) containing a pre-metered amount of the dry powder formulation (4, 14), which is in fluid communication with the inlet and the outlet, such that at least some of the air is received from the inlet into the chamber to entrain substantially all of the pre-metered amount of the dry powder formulation and to carry the pre-metered amount of the dry powder formulation out through the outlet,
a valve (6) disposed in series with the chamber for varying an extent to which the air flow (8a, 18a) through the chamber (3, 13) may flow, and
a bypass (5, 15) coupled from the inlet around the combination of the chamber and the valve, to the outlet such that a total air flow is equal to the air flow through the chamber plus an air flow through the bypass, where the bypass (5, 15) permits at least some of the air to bypass the chamber (3, 13) and permits splitting the total air flow between a primary flow (8a, 18a) through the valve and chamber, and a bypass flow (8b, 18b) through the bypass,
wherein the valve (6) is located in the primary flow such that the valve (6) closes with increased total flow such that the valve and bypass cooperate for ensuring that the air flow through the bypass increases as the total air flow increases such that the primary flow (8a, 18a) through the chamber is at least essentially fixed or kept constant through the chamber (3, 13).

US Pat. No. 10,112,018

INJECTOR APPARATUS

OWEN MUMFORD LIMITED, Ox...

1. An injector apparatus for use with a container of therapeutic material to deliver a metered dose of therapeutic material therefrom, the apparatus comprising:a first body configured to be fixed relative to the container and defining a first conduit portion for the delivery of the therapeutic material from said container;
a second body slidably connected to the first body and defining a second conduit portion, in fluid communication with the first conduit portion, the second body being provided with or configured to receive a delivery needle at a forward end of the injector apparatus through which the therapeutic material is delivered in use from the container via a conduit defined by the first conduit portion and the second conduit portion, the first body and the second body being biased towards an extended position in which the volume of the conduit is maximized;
a first non-return valve configured to prevent flow from the conduit to the container;
a second non-return valve configured to prevent flow from the needle to the conduit; and
a catch configured to hold the first body and the second body in a retracted position against said bias,
wherein relative sliding motion between the first body and the second body results in the displacement of one of the conduit portions into the other conduit portion such that the volume of the conduit may be decreased.

US Pat. No. 10,112,015

CONTINUOUS USE SYRINGE FILTER

GE HEALTHCARE UK LIMITED,...

1. A device comprising:a housing comprising a first opening for connecting to a liquid source, a second opening for connecting with an apparatus for drawing in and expelling liquid, ribs extending down an inner surface of the housing, and a valve means comprising a filter carrier and a filter, the filter carrier supporting the filter and being movable within the housing, such that movement of the filter is constrained to movement of the filter carrier;
wherein the ribs continuously constrain movement of the filter carrier and the filter to a vertical direction, and wherein the valve means permits liquid that is drawn into the housing from the liquid source by the apparatus to enter the apparatus by bypassing the filter but which forces liquid that is pushed from the apparatus through the second opening into the housing to be filtered through the filter.

US Pat. No. 10,112,013

DEVICE FOR DELIVERING A MEDICAMENT

SHL GROUP AB, Nacka Stra...

1. A device for delivery of medicament, comprising:a) an elongated housing having a proximal end and a distal end;
b) a container mounted within the housing containing a liquid medicament and a stopper slidably arranged within the container;
c) a tubular member slidably arranged within the housing and having a distally projecting tongue;
d) an actuator comprising,
a resilient member;
a plunger rod having a proximal end in contact with the stopper and a distal end being operably connected to the resilient member, where the plunger rod has longitudinally stepped dose grooves corresponding to a plurality of fixed doses; and
a carrier fixedly arranged to an inner surface of the housing and configured not to move axially relative to the housing; and
e) a dose setting mechanism comprising a selector ring axially fixed relative to the housing, the ring rotatable relative to the housing to select one of the plurality of fixed doses through engagement of the selector ring with the stepped dose grooves,
wherein axial displacement in a distal direction of the tubular member causes the tongue to project through a hole in the selector ring to disengage the carrier from engagement with the plunger rod causing the plunger rod to move proximally as a result of a biasing force exerted by the resilient member.

US Pat. No. 10,112,012

AUTOMATIC REGULATING SYSTEM FOR REGULATION OF LIQUID PRESSURE IN A HUMAN BODY

1. An automatic regulating system for regulation of liquid pressure in a body of a subject, the automatic regulating system configured to be connected to tissue of the subject, and comprising:a container configured to contain liquid;
a tubing configured to be connected between the tissue of the subject and said container, and including a first tube which is to be in fluid communication with the tissue of the subject and a second tube which is in fluid communication with said container;
a switch unit connected between said first tube and said second tube of said tubing;
a liquid pressure sensor connected to said switch unit and configured to measure liquid pressure in the tissue of the subject to obtain a liquid pressure value;
a level sensor connected to said container and configured to detect a liquid level of the liquid contained in said container; and
a control module electrically connected to said switch unit, said liquid pressure sensor and said level sensor;
wherein said switch unit is controllable to switch between a first conduction state, where fluid communication between said first tube and said second tube of said tubing is prevented while fluid communication between said first tube and said liquid pressure sensor is permitted for allowing said liquid pressure sensor to measure the liquid pressure in the tissue of the subject, and a second conduction state, where the fluid communication between said first tube and said liquid pressure sensor is prevented while the fluid communication between said first tube and said second tube is permitted so that the tissue of the subject is in fluid communication with said container; and
wherein said control module is programmed to control switching of said switch unit according to the liquid pressure value obtained by said liquid pressure sensor, and a variation in the liquid level detected by said level sensor.

US Pat. No. 10,112,010

INFUSION INJECTION SYSTEM

1. An infusion injection system comprising:a drip tube comprising an IC tag having readable information with respect to an infusion set to be connected to an infusion bottle; and
an automatic infusion device comprising a main body on which the drip tube is to be mounted,
wherein a drug solution stored in the infusion bottle is infused into a patient via the drip tube provided to the infusion set under conditions determined beforehand according to a control operation of the automatic infusion device,
wherein the automatic infusion device comprises:
a readout mechanism that starts readout of the information with respect to the infusion set held by the IC tag in response to proper mounting of the drip tube on the main body;
a storage mechanism that stores information input beforehand, which is to match the information with respect to the infusion set held by the IC tag;
an information verification mechanism that verifies information matching between the information read out by the readout mechanism and the information stored in the storage mechanism; and
a control mechanism that starts an operation, under the conditions determined beforehand, by the automatic infusion device in response to an operation start signal input by a user when the result of the verification obtained by the information verification mechanism is a match.

US Pat. No. 10,112,006

NEEDLE SHIELDING ASSEMBLIES AND INFUSION DEVICES FOR USE THEREWITH

Becton, Dickinson and Com...

1. An infusion set, comprising:a base, comprising:
a base portion having a column extending proximally therefrom, the column having a plurality of inverted J-shaped engagement structures with cantilevered ends, the engagement structures forming engagement pockets therein and being circumferentially arrayed around the column and separated by a plurality of slots;
a septum disposed within the column; and
a cannula protruding distally from the base portion and being in fluid communication with a distal side of the septum; and
a locking fluid connector, comprising:
a tubing portion having a tubing port for connecting tubing thereto; and
a hub portion for connecting with the base, the hub portion comprising:
a domed portion;
a blunt cannula for penetrating the septum, the blunt cannula extending from the domed portion and being fluidly connected with the tubing port;
a plurality of engagement fingers protruding radially inward; and
a spring element held within the domed portion by the engagement fingers;
wherein:
the engagement fingers are alignable with the aligning the slots;
the locking fluid connector is displaceable toward the base when the blunt cannula is aligned with the septum and the engagement fingers are aligned with the slots, thereby compressing the spring element;
the locking fluid connector is rotatable about the column once the engagement fingers have distally cleared the cantilevered ends of the engagement structures; and
the locking fluid is displaceable away from the base under the force of the spring element with the engagement fingers disposed within the engagement pockets to lock the fluid connector to the base in one of a plurality of discrete circumferential orientations.

US Pat. No. 10,112,005

SIZE-EFFICIENT DRUG-DELIVERY DEVICE

STEADYMED, LTD., Tel Avi...

1. A drug delivery device comprising a substantially cylindrical drug-reservoir assembly, said substantially cylindrical drug-reservoir assembly comprising:a collapsible semi-flexible drug reservoir chamber, the chamber having an interior defined by a flexible upper wall, a rigid base wall and a joint region between said flexible upper wall and said rigid base wall;
a housing;
a rigid constraining ring, which constraining ring substantially surrounds outer boundaries of the flexible upper wall, the rigid base wall or a combination thereof of said collapsible semi-flexible drug reservoir chamber, and wherein:
the constraining ring is disposed within the housing,
the constraining ring is separate from the housing, and
the constraining ring is separate from the rigid base wall;
a drug administration unit in fluid communication with said semi-flexible drug reservoir chamber; and
a displacement-generating actuator, located proximally to said semi-flexible drug reservoir chamber, wherein the displacement-generating actuator moves perpendicular to a patient skin surface upon which the drug delivery device is placed;
whereby displacement generated by said displacement-generating actuator operationally connected to said semi-flexible drug reservoir chamber, causes said flexible upper wall to collapse, promotes folding or rolling of said flexible upper wall between the displacement actuating generator and the constraining ring as said flexible upper wall collapses against the rigid base wall of said semi-flexible drug reservoir chamber within the constraints of said rigid constraining ring surrounding a circumference of said flexible upper wall, which further causes substantially expelling drug contents of said semi-flexible drug reservoir chamber toward said drug administration unit thereby delivering said drug contents from said drug delivery device.

US Pat. No. 10,112,004

INTEGRATED INTRAVENOUS (IV) CLAMP AND POWER SUPPLY

INTERNATIONAL BUSINESS MA...

1. An intravenous (IV) pole assembly, comprising:a non-conductive support element;
distribution rails respectively disposed along a length of the non-conductive support element, the distribution rails being respectively configured for power distribution along the length of the non-conductive support element; and
a clamping element comprising a hinged clamp, which is attachable to the non-conductive support element at an attachment point defined along the length of the non-conductive support element, and a connector by which power is selectively transmittable from the distribution rails to a powered device supportable on the hinged clamp.

US Pat. No. 10,112,003

BLOOD COMPONENT SEPARATION DEVICE

Terumo Kabushiki Kaisha, ...

1. A method for controlling a blood component separation device comprising:a centrifugal separator configured to separate a predetermined blood component from whole blood into a plurality of blood components; and
a container for containing the predetermined blood component centrifugally separated,
wherein the blood component separation device is configured to perform at least the following steps
(a) centrifugal separation step for introducing whole blood drawn from a donor into the centrifugal separator to separate whole blood into a plurality of blood components,
(b) circulation flow step for introducing a predetermined first blood component, among centrifugally separated blood components, separated by the centrifugal separation into the centrifugal separator together with whole blood,
(c) circulation/acceleration step, performed after a predetermined amount of the first blood component is separated in the circulation flow step, in which supply of whole blood to the centrifugal separator is stopped to introduce only the first blood component into the centrifugal separator to further circulate the first blood component for a predetermined period of time, and a circulation flow speed is then increased so that a second blood component is separated by the centrifugal separator and collected, and
(d) blood returning step for returning blood components remaining after collecting a predetermined amount of the second blood component in the circulation/acceleration step to the donor,
wherein the circulation/acceleration step includes a first collecting step for transferring a portion of the second blood component with a first concentration to a temporary storage container and
a second collecting step for collecting a portion of the second blood component with a second concentration higher than said first concentration,
wherein the second blood component with first concentration transferred to the temporary storage container is introduced into the centrifugal separator together with whole blood drawn in a following cycle, where the steps (a) to (d) constitute one cycle, and
wherein, as for the second collecting step, an amount of the second blood component with second concentration to be collected in a first cycle is set to be smallest among all cycles, and an amount of the second blood component with second concentration to be collected in a last cycle is set to be greatest among all the cycles.

US Pat. No. 10,112,002

SYSTEM FOR BLOOD SEPARATION WITH REPLACEMENT FLUID APPARATUS AND METHOD

Terumo BCT, Inc., Lakewo...

1. A disposable blood processing set for use on a centrifugal blood processing device, said disposable set comprising:a blood separation chamber adapted to be mounted on a rotor of said centrifugal blood processing device;
a blood inlet line adapted to be coupled to a blood donor and to an inlet pump on said centrifugal blood processing device;
an anti-coagulant line in fluid communication with said inlet line, said anti-coagulant line being adapted to be fluidly coupled to a supply of anti-coagulant and being further adapted to be coupled to an anti-coagulant pump on said centrifugal blood processing device;
a reservoir adapted to be coupled to at least one sensor for detecting a level of fluid in said reservoir;
a return line in fluid communication with said reservoir, said return line being adapted to be coupled to said blood donor and to a return pump on said centrifugal blood processing device;
a red blood cell line in fluid communication with said blood separation chamber and said reservoir;
a collect line in fluid communication with said blood separation chamber and in selective communication with said reservoir and a collect bag, said collect line being adapted to be coupled to a collect pump;
a plasma line in fluid communication with said blood separation chamber and with said reservoir, said plasma line being adapted to be coupled to a plasma pump; and
a replacement fluid line in fluid communication with said reservoir and adapted to be placed in fluid communication with a source of replacement fluid.

US Pat. No. 10,111,998

METHODS, SYSTEMS AND DEVICES FOR TREATING HYPERTENSION

Rox Medical, Inc., San C...

1. A method for treating a disease or disorder in a patient, the method comprising:advancing a vessel-to-to vessel guidewire through a starting vessel to a target vessel with a needle delivery device;
advancing a flow creation device over the advanced vessel-to-vessel guidewire to be positioned through vessel walls of the starting vessel and the target vessel; and
creating a flow path between the starting vessel and the target vessel with the flow creation device, wherein the flow creation device comprises a clip deployment catheter comprising an anastomotic clip and an outer sheath covering the anastomotic clip, and wherein creating the flow path comprises:
(i) moving a control of a handle of the clip deployment catheter from a first ready to deploy position to a first deployed position, thereby causing the outer sheath of the clip deployment catheter to retract a first distance relative to a distal tip of the clip deployment catheter while the anastomotic clip is held stationary relative to the distal tip, allowing at least one distal arm of the anastomotic clip to deploy,
(ii) moving the control from the first deployed position to a second ready to deploy position, and
(iii) moving the control from the second ready to deploy position to a second deployed position, thereby causing the outer sheath of the clip deployment catheter to retract a second distance relative to the distal tip of the clip deployment catheter while the anastomotic clip is held stationary relative to the distal tip, allowing at least one proximal arm of the anastomotic clip to deploy.

US Pat. No. 10,111,997

APPARATUS AND METHODS FOR ACCESSING THE LYMPHATIC SYSTEM

1. An apparatus for accessing a thoracic duct of a patient's body, the thoracic duct including an outlet adjacent a confluence of an internal jugular vein and subclavian vein of the patient's body, comprising:a tubular member comprising a proximal end, a distal end sized for introduction into a patient's vasculature, and an aspiration lumen extending between the proximal and distal ends; and
an expandable sealing member comprising:
a frame comprising a first arm and a second arm movable between a collapsed configuration and an expanded configuration;
a fluid-tight membrane comprising a first end coupled to the first arm and a second end coupled to the second arm such that the membrane is suspended between the first arm and the second arm free of additional supports, the membrane is expandable from a delivery condition sized for introduction into a patient's vasculature to a deployed condition in which the membrane defines a flexible concave outer contact surface extending between the first arm and the second arm and oriented away from the distal end, the outer contact surface configured to conform to a shape of a vessel wall surrounding the outlet of the thoracic duct for engaging a vessel wall surrounding the outlet of the thoracic duct to provide a fluid-tight seal isolating the thoracic duct from the internal jugular vein and the subclavian vein; and
an aspiration port in the outer contact surface communicating with the aspiration lumen for removing fluid from the thoracic duct through the aspiration port into the aspiration lumen.

US Pat. No. 10,111,996

VENTRICULAR ASSIST DEVICES

TC1 LLC, St. Paul, MN (U...

1. A method of controlling an implantable blood pump, the method comprising:storing preprogrammed patient specific settings within an implantable control unit;
communicating at least one of the preprogrammed patient specific settings from the implantable control unit to a non-implanted external control unit; and
controlling, by the non-implanted external control unit, operation of the implantable blood pump in accordance with the at least one of the preprogrammed patient specific settings communicated to the external control unit from the implantable control unit.

US Pat. No. 10,111,995

ELECTROACTIVE ACTUATORS

THE NOTTINGHAM TRENT UNIV...

1. An actuator comprising:an inner tubular structure; and
an outer tubular structure surrounding the inner tubular structure;
wherein:
the outer tubular structure comprises a plurality of layers of a dielectric elastomeric material;
the outer tubular structure comprises a tubular elastic support structure;
the tubular elastic support structure is configured to maintain a pre-stress in the plurality of layers of the dielectric elastomeric material;
the outer tubular structure is configured to contract in a radial direction around the inner tubular structure upon application of an actuation voltage signal across the dielectric elastomeric material layers; and
the tubular elastic support structure comprises an auxetic structure configured such that a ratio between expansion in the circumferential direction and contraction in the axial direction of the tubular elastic support structure when unconstrained is zero or negative.

US Pat. No. 10,111,993

VENTRICULAR CUFF

TC1 LLC, St. Paul, MN (U...

1. A cuff for attachment to a heart, comprising:an annular fastening member defining an opening and adapted to be attached to the heart;
a linking member coupled to the annular fastening member and disposed about the opening; and
an attachment member coupled to the linking member and disposed about the opening, the linking member extending about an outer surface of the attachment member, the attachment member configured to attach the cuff to a cannula disposed through the opening, the attachment member having at least one flanged portion extending outward from the opening in a plane generally perpendicular to a circular portion of the attachment member and offset from the annular fastening member.

US Pat. No. 10,111,991

NEGATIVE PRESSURE WOUND THERAPY DEVICE

1. A negative pressure wound therapy system, comprising:a non-woven material configured to be positioned on an appendage, the non-woven material configured to communicate negative pressure to a wound on an appendage;
a gas impermeable flexible housing material configured to be positioned over the non-woven material, the flexible housing material comprising a fold, the fold generally perpendicular to a longitudinal axis of the appendage, and
wherein the flexible housing material comprises a gasket comprising a first portion and a second portion, the gasket configured such that when the flexible housing material is folded back upon itself to surround the wound on the appendage, the first portion of the gasket is adhered to the second portion of the gasket.

US Pat. No. 10,111,990

CASSETTE CLAMP MECHANISM

Alcon Research, Ltd., Fo...

1. A surgical cassette clamping system comprising:a bracket system comprising a fastening element configured to engage a surgical cassette;
a pivot arm pivotably connected to the bracket system at a pivot location; and
a clamp motor operably connected to the bracket system to move the bracket system in a first direction;
a biasing system between the pivot arm and the bracket system, the biasing system connecting to the bracket system at a first connecting location and connecting to the pivot arm at a second connecting location to maintain a relatively consistent clamping force on the fastening element engaging the surgical cassette;
wherein the bracket system is configured to move in the first direction, and the fastening element of the bracket system is configured to move in a second direction to secure the surgical cassette;
wherein the bracket system comprises a motion bracket and a clamp bracket, the clamp bracket comprising the fastening element and the motion bracket comprising the first connecting location.

US Pat. No. 10,111,989

SPLASH-RETARDING FLUID COLLECTION SYSTEM

Medline Industries, Inc.,...

1. A splash retarding cover for a containment vessel, thesplash retarding cover comprising:
a centrally disposed suspended funnel;
a collar surrounding the centrally disposed suspended funnel;
a vessel mounting ring; and
a plurality of sloping facets circumscribing the collar and sloping outwardly from an outer circumference of the collar and terminating at the vessel mounting ring;
wherein:
the centrally disposed suspended funnel comprises a mouth and an exit port;
the collar is configured to suspend the centrally disposed suspended funnel such that an apogee of the mouth is disposed on a first side of a plane defined by the vessel mounting ring and the exit port is disposed on a second side of the plane defined by the vessel mounting ring.

US Pat. No. 10,111,988

POROUS THREE-DIMENSIONAL STRUCTURE OF POLYTETRAFLUOROETHYLENE (VERSIONS), DENTAL IMPLANT, VASCULAR IMPLANT AND TISSUE IMPLANT FOR SUBSTITUTION PLASTY OF SOFT TISSUES

1. A material for implantation made of a mixture of free-flow polytetrafluoroethylene and constrained-flow polytetrafluoroethylene, the free-flow polytetrafluoroethylene comprising granules having a size from 100 to 300 microns, the constrained-flow polytetrafluoroethylene comprising granules having a size to 20 microns;the material for implantation having a porous three-dimensional structure formed as a three-dimensional body;
the structure comprising open through pores and dead-ended pores uniformly distributed over inner surfaces of the open pores and connected with the inner surfaces;
wherein a cumulative volume of the open pores is greater than a cumulative volume of the dead-ended pores, and wherein an average size of the dead-ended pores ranges from 0.01 to 1.0 of an average size of the open pores.

US Pat. No. 10,111,986

PRODUCTION OF IN SITU CROSSLINKABLE POLYISOBUTYLENE-POLYURETHANE NANOFIBERS AND COATINGS

Cardiac Pacemakers, Inc.,...

1. A method for making an implantable medical device including a polyisobutylene-polyurethane block copolymer, the method comprising:polymerizing a polyisobutylene diol, a diisocyanate, a chain extender, and optionally a polyether diol, in a solvent system to form a polyisobutylene-polyurethane block copolymer solution;
depositing the polyisobutylene-polyurethane block copolymer solution onto at least a portion of the implantable medical device; and
evaporating the solvent system from the deposited polyisobutylene-polyurethane block copolymer solution wherein the solvent system includes one or more solvents components present during the polymerization step and the depositing step.

US Pat. No. 10,111,985

BIOCOMPATIBLE HYDROGEL POLYMER FORMULATIONS FOR THE CONTROLLED DELIVERY OF BIOMOLECULES

MEDICUS BIOSCIENCES, LLC,...

1. An in vivo gelling pharmaceutical pre-formulation, comprising:(a) one or more multi-ARM nucleophilic PEG monomers, wherein the multi-ARM PEG nucleophilic monomers comprise a polyol core, wherein the polyol core is selected from the group consisting of

wherein the polyol core is substituted with 3-8 R-groups, wherein R is:

wherein n is 1-200;
(b) one or more multi-ARM nucleophilic PEG monomers, wherein the multi-ARM PEG nucleophilic monomers comprise a polyol core, wherein the polyol core is selected from the group consisting of

wherein the polyol core is substituted with 3-8 R-groups, wherein R is:

wherein n is 1-200;
(c) one or more multi-ARM-PEG electrophilic monomers having more than two electrophilic arms, wherein each electrophilic arm comprises a PEG chain and terminates in an electrophilic group;
(d) an aqueous buffer in the pH range of about 5.0 to about 9.5; and
(e) at least one pharmaceutically active biomolecule that is a monoclonal antibody;wherein the in vivo gelling pharmaceutical pre-formulation at least in part polymerizes and/or gels at a target site of a human body to form a biocompatible hydrogel polymer,wherein the molecular weight of the multi-ARM PEG nucleophilic monomers and/or the multi-ARM PEG electrophilic monomers is about 500 to about 40000.

US Pat. No. 10,111,978

ION GENERATOR DEVICE

Global Plasma Solutions, ...

1. A system for treatment of an airflow within a combustion air intake of an engine, the system comprising an air intake conduit, an exhaust conduit, and a filter housing positioned within the air intake conduit that houses an air filter, multiple bipolar ion generators are positioned within the filter housing and each bipolar ion generator having first and second electrodes, the first electrode generating positive ions and the second electrode generating negative ions, the multiple bipolar ion generators are spaced and positioned such that the electrodes of each bipolar ion generator face away from each other.

US Pat. No. 10,111,977

METHOD AND SYSTEM FOR GENERATING NON-THERMAL PLASMA

1. An air treatment apparatus comprising:an intake portion and an output portion;
a reaction chamber located between the intake portion and output portion,
wherein the reaction chamber comprises:
an anode rail assembly comprising:
an anode rail made of a first conductive material and having a longitudinal axis, and
a plurality of discharge anode elements, wherein
each of the plurality of discharge anode elements has a proximal end and a distal end,
the proximal ends of the discharge anode elements are fixed to the anode rail, and
each of the plurality of discharge anode elements are electrically coupled to each other and to the anode rail;
a cathode rail comprising a second conductive material, wherein the cathode rail is substantially parallel to the anode rail and further wherein the cathode rail is opposite the plurality of discharge anode elements; and
the anode rail assembly and the cathode rail being located relative to each other so as to form a space, wherein the space has a central longitudinal axis and further wherein the space separates the cathode rail from the plurality of discharge anode elements such that the discharge anode elements do not cross the central longitudinal axis of the space;
an intake blower located in the intake portion, wherein the intake blower is configured to draw air into the reaction chamber; and
an alternating current power supply that is coupled to both the anode rail and the cathode rail, wherein the alternating current power supply delivers sufficient energy to generate a non-thermal plasma field in the space between the anode rail assembly and the cathode rail.

US Pat. No. 10,111,975

STERILIZATION METHODS AND APPARATUS AND ADAPTIVE CONTROL THEREOF

TS03 Inc., Quebec (CA)

1. A method for sterilizing a load in a sterilization chamber under vacuum, comprising the steps of:admitting a sterilant gas into the sterilization chamber under vacuum;
during admission of the sterilant gas monitoring a sterilant condensation related parameter in the sterilization chamber;
determining a value of the sterilant condensation related parameter, either upon the occurrence of condensation, or at the onset of condensation;
selecting a sterilization cycle among a plurality of predetermined sterilization cycles according to the value of the condensation related parameter; and
performing the selected sterilization cycle for sterilizing the load, wherein the sterilant gas is admitted at a constant rate and the sterilant condensation related parameter is the chamber pressure.

US Pat. No. 10,111,973

METHOD AND SYSTEM FOR CLEANING AND SANITIZING CONVEY LINES

Schenck Process LLC, Kan...

1. A sanitization system for sanitizing a convey line including a first end and a second end, wherein the convey line is used to convey particulate material, the sanitizing system comprising:a cleaning system configured to remove residual build-up of particulate material within the convey line, wherein said cleaning system comprises a pigging system;
an air source configured to generate a stream of air and release the stream of air into the first end of the convey line; and
an ozone generation and delivery module configured to inject ozone into the air stream,
wherein the ozone generation and delivery module includes a humidifier configured to inject moisture into the air stream,
wherein a combination of ozone and moisture injected into the air stream is configured to kill and/or remove contaminants from the convey line.

US Pat. No. 10,111,972

MOBILE STERILIZATION APPARATUS AND METHOD FOR USING THE SAME

PMBS, LLC, Nutley, NJ (U...

1. A sterilization cabinet for use with an autoclave for sterilizing surgical equipment or a surgical tray, the sterilization cabinet comprising:a plurality of panels forming a chamber, the plurality of panels arranged such that a first side of the chamber comprises an open frame, wherein at least one of the plurality of panels is a floor panel at a bottom of the chamber, the floor panel having a lowest point configured to drain liquids from the chamber;
at least one door having a gasket, where the at least one door and the gasket are configured to secure to the open frame to create a closed configuration in which the at least one door seals the chamber;
a vent formed in at least one of the plurality of panels;
at least one first filter covering the vent and a filter cover configured to hold the at least one first filter against the vent;
wherein an entirety of the floor panel is pitched such that any condensate is directed by gravity towards the lowest point in the floor panel;
a second filter in fluid communication with the lowest point in the floor panel such that any condensate flowing on the entirety of the floor panel passes through the second filter; and
at least one rack structure removably positioned within the chamber and configured for supporting the surgical equipment or the surgical tray above the floor panel.

US Pat. No. 10,111,971

MAGNETIC NANOPARTICLES

The General Hospital Corp...

1. A method of determining the presence of a target molecule in a subject, the method comprising:administering to the subject a nanoparticle, wherein the nanoparticle comprises:
a solid ferromagnetic core;
a super-paramagnetic shell on and contacting the surface of and surrounding the solid ferromagnetic core, wherein the super-paramagnetic shell has a thickness between about 0.5 nm and about 3 nm; and
a targeting moiety on the super-paramagnetic shell that specifically binds to the target molecule;
providing sufficient time for the nanoparticle to bind to the target molecule; and
generating a magnetic resonance image of the subject, wherein a signal in the image indicates the presence of the target molecule.

US Pat. No. 10,111,969

UPAR TARGETING PEPTIDE FOR USE IN PEROPERATIVE OPTICAL IMAGING OF INVASIVE CANCER

RIGSHOSPITALET, Copenhag...

1. A fluorophore labeled uPAR-targeting peptide conjugate comprising the formulaand pharmaceutically acceptable salts thereof.

US Pat. No. 10,111,963

NANOPARTICLE DRUG CONJUGATES

Memorial Sloan Kettering ...

1. A nanoparticle drug conjugate (NDC) comprising:a non-mesoporous nanoparticle;
an enzyme sensitive linker moiety; and
a drug moiety,
wherein the non-mesoporous nanoparticle comprises a silica-based core and a silica shell surrounding a least a portion of the core,
wherein the NDC has a diameter less than 10 nm,
wherein the non-mesoporous nanoparticle is coated with an organic polymer, and
wherein the drug moiety and enzyme sensitive linker moiety form a cleavable linker-drug construct that is covalently linked to the non-mesoporous nanoparticle and that facilitates enzyme catalyzed drug release.

US Pat. No. 10,111,962

PEPTIDE-LINKED MORPHOLINO ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF MYOTONIC DYSTROPHY

Genzyme Corporation, Cam...

1. A method for treating or preventing myotonic dystrophy type 1 (DM1) in an individual in need thereof comprising: systemically administering to the individual a therapeutically effective amount of a cationic peptide-linked morpholino antisense oligonucleotide comprising: (a) a morpholino antisense oligonucleotide sequence complementary to at least 3 polyCUG repeat sequences in a 3? untranslated region (UTR) of a dystrophia myotonica protein kinase (DMPK) RNA transcript target; and (b) a spacer moiety linking the morpholino antisense oligonucleotide and a cationic peptide, the space moiety comprisingwherein administration of the cationic peptide-linked morpholino antisense oligonucleotide relieves at least one symptom of DM1 in at least two muscles.

US Pat. No. 10,111,956

CORTICOSTEROID COMPOSITIONS

Tolmar, Inc., Fort Colli...

1. A pharmaceutical composition comprising:a mixture of solvent components, comprising propylene glycol monocaprylate and propylene glycol in a ratio from 90:10 to 25:75; and
a corticosteroid selected from hydrocortisone or hydrocortisone acetate at 1.0% w/w to 5.0% w/w of the pharmaceutical composition, wherein the corticosteroid is dissolved in the solvent mixture at 1.25% w/w to 1.70% w/w of the solvent mixture;
wherein the pharmaceutical composition is a topical formulation selected from a cream, gel, and ointment.

US Pat. No. 10,111,955

PEG DERIVATIVE

Delta-Fly Pharma, Inc., ...

5. A pharmaceutical composition, comprising the compound according to claim 1, or a salt thereof, and a pharmaceutically acceptable salt.

US Pat. No. 10,111,951

HUMAN INKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS

ACADEMIA SINICA, Taipei ...

1. A method for augmenting an immunogenicity of an antigen in a subject in need thereof, comprising co-administering said antigen with an adjuvant composition comprising a compound having a structure of Formula (I):
or a pharmaceutically acceptable salt thereof;
wherein:
R1 is —OH or halogen;
R2 is —OH or halogen;
R3 is hydrogen;
R4 is selected from the group consisting of optionally substituted carbocyclyl, optionally substituted aryl, optionally substituted heterocyclyl, optionally substituted heteroaryl, optionally substituted alkoxy, an optionally substituted amino group, and optionally substituted acyl;
R5 is selected from the group consisting of hydrogen, halogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted aryl, optionally substituted heterocyclyl, optionally substituted heteroaryl, optionally substituted alkoxy, an optionally substituted amino group, and optionally substituted acyl;
n is an integer of 1 to 15, inclusive; and
m is an integer of 1 to 20, inclusive.

US Pat. No. 10,111,947

VIRUS-CONTAINING FORMULATION AND USE THEREOF

Transgene S.A., Illkirch...

1. A freeze-dried formulation comprising (i) at least one attenuated or recombinant poxvirus-based material, (ii) between 5 g/L and 80 g/L of at least one polymer selected from the group consisting of polyvinylpyrrolidone and derivatives thereof, (iii) between 20 g/L and 80 g/L of at least one disaccharide, (iv) arginine and glutamate, (v) between 0.1 g/L and 5 g/L of at least one pharmaceutical acceptable phosphate salt, and between 1 g/L and 5 g/L of at least one pharmaceutical acceptable monovalent salt and, optionally (vi) a pharmaceutical acceptable buffer wherein the pH of the formulation is comprised between about 7 and about 8.5.

US Pat. No. 10,111,936

METAL-GLYCOPROTEIN COMPLEXES AND PHOTODYNAMIC THERAPY OF IMMUNE PRIVILEGED SITES WITH SAME

Theralase Technologies, I...

1. A method for treating a condition associated with hyperproliferating cells, said method comprising administering to a subject having the condition a metal-binding glycoprotein and a chemotherapeutic compound containing at least one transition metal, wherein the metal-binding glycoprotein and the chemotherapeutic compound containing at least one transition metal are administered in a combined amount effective to treat the condition, and the chemotherapeutic compound has the formula(I):including hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, wherein:M at each occurrence is independently selected from the group consisting of osmium, manganese, molybdenum, rhenium, ruthenium, iron, cobalt, rhodium, iridium, nickel, platinum, and copper;
X is selected from the group consisting of Cl?, PF6?, Br?, BF4?, ClO4?, CF3SO3?, and SO4?2;
n=0, 1, 2, 3, 4, or 5;
q is independently at each occurrence 0, 1, or 2;
y is independently at each occurrence 0, 1, or 2;
z is independently at each occurrence 1, 2, or 3;
Lig1 is a bidentate ligand that at each occurrence is each independently selected from the group consisting of

Lig2 is a bidentate ligand that at each occurrence is each independently selected from the group consisting of

Lig3 is a bidentate ligand that at each occurrence is each independently selected from the group consisting of

R1 is selected from the group consisting of hydrogen, optionally substituted phenyl, optionally substituted aryl, optionally substituted heteroaryl, 4-pyridyl, 3-pyridyl, 2-thiazole, 2-pyrolyl, 2-furanyl,

u is an interger;
R2a, R2b, R2c, R2d, R2e, R2f, R2g, R2h, R2i, R2j, R2k, and R2l at each occurrence are each independently selected from the group consisting of hydrogen, C1-6 optionally substituted alkyl, C1-6 optionally substituted branched alkyl, C3-7 optionally substituted cycloalkyl, C1-6 optionally substituted haloalkyl, C1-6 optionally substituted alkoxy, CO2R5, CONR62, NR72, SO3H, sulfate, sulfonate, optionally substituted aryl, optionally substituted aryloxy, optionally substituted heteroaryl, and optionally substituted heterocycle,
R3a, R3b, R3c, R3d, R3e, R3f, R3g, R3h, R3i, R3j, R3k, and R3l at each occurrence are each independently selected from the group consisting of hydrogen, C1-6 optionally substituted alkyl, C1-6 optionally substituted branched alkyl, C1-6 optionally substituted haloalkyl, C1-6 optionally substituted alkoxy, optionally substituted phenyl, and CO2R8;
R4a, R4b, and R4c at each occurrence are each independently selected from the group consisting of hydrogen, C1-6 optionally substituted alkyl, C1-6 optionally substituted branched alkyl, C1-6 optionally substituted cycloalkyl, C1-6 optionally substituted haloalkyl, C1-6 optionally substituted alkoxy, CO2R5, CONR62, NR72, sulfate, sulfonate, optionally substituted aryl, optionally substituted aryloxy, optionally substituted heteroaryl, and optionally substituted heterocycle;
R4a and R4b at each occurrence on a thiophene ring are taken together with the atom to which they are bound to form an optionally substituted ring having from 6 ring atoms containing 2 oxygen atoms;
R5 at each occurrence are each independently selected from the group consisting of hydrogen and optionally substituted alkyl;
R6 at each occurrence are each independently selected from the group consisting of hydrogen and optionally substituted alkyl;
R7 at each occurrence are each independently selected from the group consisting of hydrogen and optionally substituted alkyl; and
R8 at each occurrence are each independently selected from the group consisting of hydrogen and optionally substituted alkyl.

US Pat. No. 10,111,910

METHODS FOR TREATING CARDIAC CONDITIONS

MiMedx Group, Inc., Mari...

1. A method for treating injured or diseased cardiac tissue, which method comprises placing an effective amount of a composition comprising dehydrated modified placental tissue proximate to the injured or diseased cardiac tissue without obstructing the function thereof, wherein the dehydrated modified placental tissue is placed to promote treatment of the disease or healing of the injured or diseased cardiac tissue;wherein the modified placental tissue comprises a dehydrated chorion and a dehydrated amnion, said dehydrated amnion having an epithelial cell layer and/or a fibroblast layer, and said dehydrated chorion having a fibroblast layer.

US Pat. No. 10,111,902

POLYMERS FOR REVERSING HEPARIN-BASED ANTICOAGULATION

University of British Col...

1. A controlled release delivery device comprising:a support having a surface;
a heparin binding polymer attached to the surface, the heparin binding polymer comprising:
a first dendritic polyol;
one or more cationic moieties, at least one of the one or more cationic moieties attached to the first dendritic polyol; and
at least one cleavage site; and
heparin bound to the heparin binding polymer, wherein the heparin binding polymer has the structure of Formula (I):

wherein L1, L2, L3, L4 and L5 comprise dendritic polyols.

US Pat. No. 10,111,893

CALMANGAFODIPIR, A NEW CHEMICAL ENTITY, AND OTHER MIXED METAL COMPLEXES, METHODS OF PREPARATION, COMPOSITIONS, AND METHODS OF TREATMENT

PLEDPHARMA AB, Stockholm...

1. A method for treatment of oxidative stress associated with a pathological condition in a patient, the method comprising administering to the patient a pharmaceutical composition formed by suspending or dissolving a mixed metal complex of a compound of Formula I, or a salt thereof, in a liquid medium, the pharmaceutical composition being administered in an amount effective to reduce the oxidative stress, wherein the mixed metals comprise calcium and manganese, and wherein the molar ratio of calcium to manganese is 1-10:
wherein
X represents CH,
each R1 independently represents hydrogen or —CH2COR5;
R5 represents hydroxy;
each R2 independently represents ZYR6 wherein Z represents a bond, or a C1-3 alkylene or oxoalkylene group, optionally substituted by R7;
Y represents a bond or an oxygen atom;
R6 is a hydrogen atom, COOR8, alkyl, alkenyl, cycloalkyl, aryl or aralkyl group, optionally substituted by one or more groups selected from COOR8, CONR82, NR82, OR8, ?NR8, ?O, OP(O)(OR8)R7 and OSO3M;
R7 is hydroxy, optionally hydroxylated, optionally alkoxylated alkyl or aminoalkyl group;
R8 is a hydrogen atom or an optionally hydroxylated, optionally alkoxylated alkyl group;
M is a hydrogen atom or one equivalent of a physiologically tolerable cation;
provided that each ZYR6 includes a —CH2O— linkage to the respective pyridine ring;
R3 represents ethylene; and
each R4 independently represents hydrogen or C1-3 alkyl.

US Pat. No. 10,111,885

COMPOSITIONS AND THERAPEUTIC METHODS FOR THE TREATMENT OF COMPLEMENT-ASSOCIATED DISEASES

Resverlogix Corp., Calga...

1. A method for treating a complement-associated disease or disorder selected from paroxysmal nocturnal hemoglobinuria, familial CD59 deficiency, cold agglutinin disease, hereditary angioedema, hemolytic anemia, and thrombocytopenia by modulating the complement system in a subject in need thereof comprising administering a therapeutically effective amount of at least one compound of Formula I or a stereoisomer, tautomer, pharmaceutically acceptable salt, or hydrate thereof, wherein:
R1 and R3 are each independently selected from alkoxy, alkyl, amino, halogen, and hydrogen;
R2 is selected from alkoxy, alkyl, alkenyl, alkynyl, amide, amino, halogen, and hydrogen;
R5 and R7 are each independently selected from alkyl, alkoxy, amino, halogen, and hydrogen;
R6 is selected from amino, amide, alkyl, hydrogen, hydroxyl, piperazinyl, and alkoxy, wherein the alkoxy is optionally substituted with one or more groups chosen from amide, amine, aryl, benzyloxy, carbamate, carboxy, heterocyclyl, hydroxyl, methoxy, and sulfonamide; and
W is CH or N.

US Pat. No. 10,111,882

SYK INHIBITORS

GILEAD SCIENCES, INC., F...

1. A method of treating or reducing aplastic anemia in a patient in need thereof, comprising administering to the patient an effective amount of a compound selected from:or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,111,881

INHIBITORS OF MACROPINOCYTOSIS IN PREVENTION AND TREATMENT OF DISEASE

Texas Biomedical Research...

1. A method for treating or preventing an infection in a subject, the method comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition having the general formula (I) or a pharmaceutically acceptable salt thereof, wherein the infection is an Ebolavirus infection or a Marburgvirus infection:

US Pat. No. 10,111,880

COMPOUNDS FOR THE TREATMENT OF DIABETES AND DISEASE COMPLICATIONS ARISING FROM SAME

BEN-GURION UNIVERSITY OF ...

1. A method of treating diabetes or diabetes related complications in a subject in need thereof, said method comprising administering to a subject an effective amount of a compound represented by the structure of formula I:
wherein
Z is carbon, phosphorus, or nitrogen;
R1, R3, R4, R6, R7 and R9 are the same or different H, halogen, haloC1-6alkyl, aryl, C1-6alkyl, cycloC1-6alkyl, heterocycloC1-6alkyl, C1-6alkoxy, monoC1-6alkylamino, diC1-6alkylamino or arylamino;
R2, R5 and R8 are the same or different H, halogen OH, C1-6alkyl, or C1-6alkoxy; and
R10 is nothing when Z is phosphorous or nitrogen, and OH or C1-6alkyl when Z is carbon.

US Pat. No. 10,111,878

N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER

Agios Pharmaceuticals, In...

1. A method of treating acute myelogenous leukemia characterized by the presence of an IDH2 mutation, comprising the step of administering to the patient a therapeutically effective amount of a compound having Formula II:or a pharmaceutically acceptable salt thereof, wherein:ring A? is selected from phenyl, pyrimidin-2-yl, pyrimidin-4-yl, pyrimidin-5-yl, oxazol-4-yl, isoxazol-3-yl, thiazol-2-yl, pyridin-3-yl and pyridin-2-yl, wherein ring A? is optionally substituted with one or two substituents independently selected from 1-propenyl, -cyclopropyl-OH, chloro, fluoro, —CF3, —CHF2, —CH3, —CH2CH3, —CF2CH3, —S(O)CH3, —S(O)2CH3, —CH2OH, —CH(OH)CH3, —CH(OH)CF3, —OH, —OCH3, —OCF3, —OCH2CH3, —C(O)—NH2, —CH2NH2, —NH2, —NH(CH3), —CN and —N(CH3)2; and
ring B? is selected from phenyl, pyridin-3-yl, pyridin-4-yl, pyridazin-4-yl, isoxazol-4-yl, isoxazol-3-yl, thiazol-5-yl, pyrimidin-5-yl and pyrazol-4-yl, wherein ring B? is optionally substituted with one to two substituents independently selected from halo; —CN; —OH; C1-C4 alkyl optionally substituted with halo, CN or —OH; —S(O)2—C1-C4 alkyl; —S(O)—C1-C4 alkyl; —S(O)2—NH—C1-C4 alkyl; —S(O)2—NH—CH2—CF3; —S(O)2—N(C1-C4 alkyl)2; —S(O)2-azetidin-1-yl; —O—C1-C4 alkyl; —CH2—O—CH3, morpholin-4-yl, cyclopropyl, cyclopropyl-C1-C4 alkyl, cyclopropyl-C1-C4 alkoxy, cyclopropyl-CN, —S(O)2—NH-cyclopropyl; —S(O)2—NH—CH2-cyclopropyl; —C(O)—C1-C4 alkyl, —C(O)—O—CH3; wherein:
a. ring A? and ring B? are not both an optionally substituted phenyl;
b. when ring A? is unsubstituted pyridyl, then ring B? is not phenyl optionally substituted with one to three groups independently selected from methyl, ethyl, t-butyl, methoxy, CH(OH)CH3, Cl, Br, and CF3;
c. when ring A? is oxazol-4-yl, isoxazol-3-yl, or thiazol-2-yl, then ring B? is not phenyl optionally substituted with one to two groups independently selected from F, Cl, SO2CH3, C(O)OCH3, methyl, ethyl, t-butyl, methoxy, ethoxy, CF3, and OH;
d. the compound is not:
(2) 6-(6-methoxy-3-pyridinyl)-N2-(4-methylphenyl)-1,3,5-triazine-2,4-diamine;
(3) 6-(2-methoxy-3-pyridinyl)-N2-(4-methylphenyl)-1,3,5-triazine-2,4-diamine.

US Pat. No. 10,111,820

COMPOSITION FOR HAIR FRIZZ REDUCTION

The Procter and Gamble Co...

1. A rinse-off conditioner composition for hair frizz reduction comprising:from about 0.2% to about 20.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following:

wherein R is hydrogen or metal ion, R6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R7, R8, R9, R10, R11, and R12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups;

an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and
wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms;
c) alcohol comprising an unsaturated double bond in the C2 position;
d) an alkyl-substituted glycol wherein the structure of such alkyl substituted glycol contains less than 20 carbon atoms;
e) a monoalkyl or dialkyl substituted glycerin or mono- or di-esters of glycerin with fatty acids, wherein the structure of such monoalkyl- or di-alkyl-substituted glycerin or glycerin esters contains less than 20 total carbon atoms;

wherein R15 could be hydrogen, alkyl, alkenyl, phenyl group and wherein the structure of the R15 group contain less than 20 carbon atoms; or
g) a fatty acid ester containing from 15-40 total carbon atoms;
and wherein the moisture control material is weakly to non-acidic and further wherein the moisture control material has protein binding higher than 10, a log P higher than 0.5, a pKa of 5 or higher and a hydrogen-binding higher than 4 and wherein the rinse-off conditioner composition exhibits at least about a 4% frizz reduction versus control composition without the moisture control materials wherein the rinse-off conditioner composition comprises at least one moisture control material selected from group consisting of 2-hexyl-1-decanol, isostearyl isostearate or mixtures thereof and further comprising from about 0.5% to about 2% of salicylic acid, chlorosalicylic acid or mixtures thereof, and from about 2% to about 10% of 2-hydroxyethyl urea.

US Pat. No. 10,111,807

CARTRIDGE PORTION OF TRANSDERMAL DRUG DELIVERY APPARATUS AND METHODS

Sorrento Therapeutics, In...

1. A cartridge for supplying fluid in a transdermal drug delivery apparatus, the cartridge comprising:a body at least partially defining
an interior for containing the fluid,
a first cavity including a cylindrical section and a frustoconical section, the cylindrical section tapering to the frustoconical section,
a second cavity,
a passageway connected between the cylindrical section of the first cavity and the second cavity, and
first and second openings to the interior of the body,
wherein the first and second openings are respectively defined by opposite first and second ends of the body, wherein the first opening is contiguous with the first cavity, and the second opening is contiguous with the second cavity;
a self-sealing member at least partially closing the first opening; and
a movable member at least partially closing the second opening, wherein at least a portion of the movable member is configured for being urged into the interior of the body for increasing pressure within the interior of the body.

US Pat. No. 10,111,761

METHOD OF CONTROLLING PROSTHETIC DEVICES WITH SMART WEARABLE TECHNOLOGY

International Business Ma...

1. A method for mode selection of a prosthesis, the method comprising:receiving, by a wearable device, a first input from a user, wherein (i) the wearable device is a ring that comprises a rotatable housing with a touch surface sensitive surface, and (ii) the first user input comprises the user touching the touch surface;
determining, by the wearable device, the first input indicates a change to a user-activated mode of operation of the prosthesis;
sending, by the wearable device, a first command to the prosthesis to change the user-activated mode of operation of the prosthesis;
in response to receiving the first command by the prosthesis, operating one or more control devices of the prosthesis to change a current user-activated mode of operation of the prosthesis based, at least in part, on the determined user-activated mode of operation associated with the received first input;
receiving, by the wearable device, a second input from a user;
determining, by the wearable device, the second input indicates an activation operation of the prosthesis;
sending, by the wearable device, a second command to the prosthesis to activate the prosthesis; and
in response to receiving the second command by the prosthesis, operating the one or more control devices of the prosthesis to perform an action associated with the current user-activated mode of operation of the prosthesis.

US Pat. No. 10,111,744

METHOD OF MAKING A PROSTHESIS DEVICE

Establishment Labs S.A., ...

1. A method of making a prosthesis device comprising a flexible shell and a filling material, said method comprising:forming a plurality of first layers by coating a mold with a first silicone material, wherein the plurality of first layers has a first thickness and a first color;
forming one or more second layers by coating the plurality of first layers with a second silicone material, comprising:
a polydimethylsiloxane polymer having at least 10 mole percent of a pendant chemical group chosen from a diphenyl group, a methylphenyl group, a trifluoropropyl group, or a combination thereof;
a vinyldimethyl-terminated polydimethylsiloxane polymer; and
a pigment,
the one or more second layers providing a diffusion barrier to impede passage of the filling material through the shell, wherein the one or more second layers has a second thickness and a second color different from the first color of the plurality of first layers;
forming a plurality of third layers by coating the one or more second layers with the first silicone material, wherein the plurality of third layers has a third thickness greater than the second thickness and the same color as the first color of the plurality of first layers, and wherein a total thickness of the shell, comprising the first thickness, the second thickness, and the third thickness, ranges from 0.33 mm to 1.00 mm; and
verifying the presence of the one or more second layers in the shell by visual observation of the second color in the shell, the one or more second layers being visually distinguishable through the plurality of first layers without the use of an optical comparator, specialized equipment, or destructive tests.

US Pat. No. 10,111,737

INTRAVAGINAL INSERT FOR INCONTINENCE MANAGEMENT

1. An intravaginal insert for treating urinary incontinence, comprising:an insert body having an outer surface being constructed of a substantially non-absorbent material, said outer surface extending continuously between a proximal end of the insert body to a distal end of the insert body and having an outer surface shape that remains substantially unchanged to insert and remain secure within a vagina and support a urethra anteriorly through the vagina;
a core substantially immovably secured within the insert body that is stiffer than the insert body, said insert body forming a solid volume extending from said outer surface to said core from said proximal end to said distal end; and
a tether operatively connected to the insert body to extend out of the vagina to remove the insert body from the vagina after use.

US Pat. No. 10,111,730

ORTHODONTIC ALIGNER WITH ISOLATED SEGMENTS

Align Technology, Inc., ...

1. A method comprising:forming a first segment of a plastic orthodontic aligner for moving a first set of teeth of a patient;
forming a second segment of the plastic orthodontic aligner; and
joining the first segment of the plastic orthodontic aligner to the second segment of the plastic orthodontic aligner using a connector configured to minimize force transmission between the first segment and the second segment;
wherein the connector is configured to be disposed along one or more additional teeth of the patient without exerting a clinically significant force on the one or more additional teeth, wherein the connector spans a gap between the first segment and the second segment, the gap corresponding to the one or more additional teeth that are not to receive the clinically significant force, wherein the connector comprises a flexible material that will perform at least one of flex, move or change shape responsive to applied forces, wherein the connector is configured to isolate first forces applied to the first set of teeth covered by the first segment from separate and distinct second forces applied to a second set of teeth covered by the second segment, and wherein isolation of the first forces from the second forces enables a) the first forces to be applied to the first set of teeth without substantial interference from the second forces applied to the second set of teeth and b) the second forces to be applied to the second set of teeth without substantial interference from the first forces applied to the first set of teeth.

US Pat. No. 10,111,727

SURGICAL SPECIMEN MARKING MECHANISM

DB PATENT HOLDING COMPANY...

1. An apparatus comprising:an endoscopic clip placement tool;
a first marking clip adapted to be attached with the clip placement tool to a first area associated with a specimen mass, the specimen mass having an outer margin that defines the shape of the specimen mass;
a second marking clip adapted to be attached to a second area associated with tissue surrounding the specimen mass and outside the margin; and
wherein the first area and the second area are located on direct opposite sides of the margin, such that the first marking clip and the second marking clip identify the orientation of the specimen mass relative to the tissue surrounding the specimen mass.

US Pat. No. 10,111,723

SYSTEM AND METHOD FOR DETECTION AND AVOIDANCE OF COLLISION OF ROBOTICALLY-CONTROLLED MEDICAL DEVICES

St. Jude Medical, Atrial ...

1. A method of operating a robotic control system that is configured to manipulate a medical device including one or more nodes and which includes an electronic control unit and a computer-readable memory coupled to the electronic control unit, said method comprising the steps of:providing, for each of the one or more nodes of the medical device, a respective position sensor configured to produce a respective signal from which respective node locations in a reference coordinate system can be determined;
generating a first virtual representation associated with the medical device using the one or more determined node locations;
generating a second virtual representation associated with an object;
determining, using said control unit, a collision metric indicative of a collision between said medical device and said object based on said virtual representations in accordance with a predetermined detection strategy.

US Pat. No. 10,111,720

MOTORIZED DEVICES

1. A mobile device comprising: a motor, wherein:a. the motor comprises a lead car, an intermediate car, and a trail car;
b. each of the lead car, the intermediate car, and the trail car comprises an electromagnet, wherein each of the electromagnets is independently operable;
c. the intermediate car weighs less than the lead car;
d. the intermediate car weighs less than the trail car;
e. the lead car weighs less than a combined weight of the intermediate car and the trail car; and
f. the trail car weighs less than a combined weight of the intermediate car and the lead car.

US Pat. No. 10,111,719

CONTROL OF THE RATE OF ACTUATION OF TOOL MECHANISM BASED ON INHERENT PARAMETERS

Ethicon LLC, Guaynabo, P...

1. A robotic surgical system comprising:a robotic arm having a proximal end configured to be coupled to a support and having a driver at a distal end of the robotic arm, the driver including one or more motors;
a tool assembly comprising
a housing configured to releasably couple to the driver, the housing including a first actuator and a second actuator that are each actuated by at least one of the one or more motors;
a shaft extending distally from the housing and operatively coupled to the first actuator such that actuation of the first actuator causes the shaft to rotate; and
an end effector pivotally coupled to a distal end of the shaft, the end effector being configured to pivot upon actuation of the second actuator to form an angle between a first longitudinal axis of the end effector and a second longitudinal axis of the shaft; and
a control system configured to control, based on the angle formed from a current position of the end effector, a velocity of movement of the robotic arm, the velocity of movement being related to the angle.

US Pat. No. 10,111,715

ADJUSTABLE LENGTH MEDICAL INSTRUMENT ASSEMBLY WITH LOCALIZATION ELEMENTS FOR TRACKING MEDICAL INSTRUMENT EXTENSION

Veran Medical Technologie...

1. A system for tracking the movement of a medical instrument comprising:(i) a catheter comprising an elongate flexible shaft having a proximal end portion comprising a port, an opposite distal end portion terminating in a tip, and a working channel extending from the port to an exit proximate the tip;
(ii) a medical instrument assembly at least a portion of which is adapted to be inserted into the working channel of the catheter, the medical instrument assembly comprising:
a handle assembly having a first end and a second end, the handle assembly comprising a first handle portion proximate the first end and a second handle portion proximate the second end, wherein the second handle portion is slidably engaged with the first handle portion;
a first localization element providing an output attached to the first handle portion;
a second localization element providing an output attached to the second handle portion; and
a medical instrument having a proximal end and a distal end, wherein the proximal end is mechanically coupled to the second handle portion and wherein a translation of the second handle portion with respect to the first handle portion causes a movement of the medical instrument, the movement corresponding to an extension of the distal end of the medical instrument from the tip; and
(iii) a navigation system adapted to receive the output of the first localization element and second localization element and from that output determine a first position of the first localization element and a second position of the second localization element, and wherein the navigation system is adapted to determine the extension of the distal end of the medical instrument relative to the tip by calculating the distance between the first localization element and the second localization element based on the first position of the first localization element and the second position of the second localization element.

US Pat. No. 10,111,708

SYSTEM AND METHOD FOR LOCATING AND IDENTIFYING THE FUNCTIONAL NERVES INNERVATING THE WALL OF ARTERIES AND CATHETERS FOR SAME

SYMAP MEDICAL (SUZHOU), L...

1. A method of mapping a parasympathetic renal nerve, comprising the steps of:a) introducing a catheter into the lumen of a renal artery such that a tip of said catheter contacts a site on an inner wall of said renal artery;
b) measuring one or more physiological parameters to obtain baseline measurements before introducing an electrical current to the site, said physiological parameters are selected from the group consisting of systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate;
c) applying electrical stimulation by introducing said electrical current to the site via the catheter, wherein said electrical current is controlled to be sufficient to elicit changes in said physiological parameters when there is an underlying parasympathetic nerve at the site; and
d) measuring said physiological parameters at a specific time interval after each electrical stimulation, wherein a decrease of said physiological parameters below the baseline measurements after said electrical stimulation would indicate that a parasympathetic renal nerve has been mapped at said site.

US Pat. No. 10,111,705

INTEGRAL ELECTRODE PLACEMENT AND CONNECTION SYSTEMS

INTUITIVE SURGICAL OPERAT...

1. A tissue treatment assembly, comprising:an elongate catheter extending along a longitudinal axis and terminating at a distal opening;
a fluid barrier projecting distally of the distal opening of the catheter and configurable between a low profile and a deployed profile, wherein in the deployed profile, the fluid barrier defines an open area in fluid communication with the distal opening of the catheter and with an environment external to the fluid barrier; and
a circuit portion including at least one exposed electrode disposed on the fluid barrier, wherein the at least one exposed electrode is disposed on a distal membrane of the fluid barrier, the distal membrane including a surface extending generally perpendicular to the longitudinal axis of the catheter.

US Pat. No. 10,111,702

SURGICAL INSTRUMENT

Covidien LP, Mansfield, ...

1. An articulation assembly, comprising:a proximal pivoting member defining a first pivot axis;
an articulation member coupled to the proximal pivoting member, wherein movement of the articulation member rotates the proximal pivoting member about the first pivot axis;
a distal pivoting member defining a second pivot axis; and
at least one link operably coupling the proximal pivoting member and the distal pivoting member, a distal end of the proximal pivoting member and a proximal end of the distal pivoting member defining complementary surfaces.

US Pat. No. 10,111,697

DEVICE FOR DELIVERING VISCOUS MATERIAL

DePuy Synthes Products, I...

1. A system for delivering a viscous material into a site in a patient, comprising:an actuator including an actuator vessel and an electric motor;
a delivery tube, having a first end, a second end and an inner bore, wherein the first end is coupled to the actuator;
a plunger housed within the delivery tube, and
a container having a connection port for connecting to the second end of the delivery tube and an exit port, and containing a viscous material, wherein the viscous material is a PMMA-based bone cement, and
wherein the actuator is adapted to advance the plunger.

US Pat. No. 10,111,665

ELECTROMECHANICAL SURGICAL SYSTEMS

Covidien LP, Mansfield, ...

1. An electromechanical surgical system, comprising:a hand held electromechanical surgical device including at least one rotatable drive connector supported in a handle housing;
an adapter assembly selectively connectable to the surgical device, the adapter assembly including at least one rotatable drive sleeve configured to receive the at least one rotatable drive connector, a single rotatable drive shaft rotatably connected to the at least one rotatable drive sleeve and longitudinally extending to the distal end of the adapter assembly, and a gear disposed around a distal end of the rotatable drive shaft and configured to rotate with the rotatable drive shaft; and
a surgical loading unit comprising an anvil jaw and a cartridge jaw that are operatively joined to one another such that the anvil jaw and the cartridge jaw are movable between open and closed positions relative to one another, the cartridge jaw including:
a mounting portion defining a receiving channel;
a power screw disposed within the receiving channel of the mounting portion;
a gear member mounted on a proximal portion of the power screw and operably engagable with the gear of the adapter assembly; and
a locking mechanism disposed within the mounting portion for locking the surgical loading unit to the adapter assembly, the locking mechanism being movable between an unlocked position when the cartridge jaw is free of a cartridge and a locked position when a cartridge is loaded into the cartridge jaw.

US Pat. No. 10,111,660

SURGICAL STAPLER FLEXIBLE DISTAL TIP

Covidien LP, Mansfield, ...

1. A tool assembly for a surgical device, comprising:a first jaw member defining a first tissue contact surface;
a second jaw member defining a second tissue contact surface, the first jaw member and the second jaw member being movable in relation to each other between open and closed positions, wherein, in the closed position, the first and second tissue contact surfaces are spaced apart from each other and define a tissue gap; and
a compressible material secured to a distal end of the first jaw member,
the compressible material engaging the second jaw member when the first and second jaw members are in the closed position and including a textured surface having raised protrusions that are configured to contact tissue of a subject.

US Pat. No. 10,111,651

SYSTEM AND METHOD OF ANCHORING SUPPORT MATERIAL TO TISSUE

1. A method of anchoring a support material to tissue, the method comprising:forming an incision in a urogenital triangle of a patient for access to a pelvis of the patient;
inserting a body portion of an anchor into a lumen in a cannula and having a spine portion of the anchor extending radially out of a wall of the cannula, where the anchor has a suture connected to the anchor with a body portion of the suture trailing away from the anchor;
inserting a leading end of the cannula and the anchor into the incision;
pushing the leading end of the cannula into periosteum tissue of the pelvis and engaging the spine portion of the anchor with the periosteum tissue;
withdrawing the leading end of the cannula from the incision and leaving the anchor engaged in the periosteum tissue with the body portion of the suture extending from the anchor, through the incision, to a location exterior of the patient;
securing the support material to the suture that is attached to the anchor; and
delivering the support material over and along the suture from the location exterior of the patient, through the incision, and to the pelvis of the patient.

US Pat. No. 10,111,650

PEDICLE MOUNTABLE RETRACTOR SYSTEM

Minimal Invasive Technolo...

1. A retractor system comprising:a first tower comprising
a first tube having a screw gripping formation in the form of elastic spring biased parts, for removably mounting the first tower on a first surgical screw;
a centre shaft comprising a transverse formation at a distal end thereof; and
an inner tube having an external thread towards a distal end thereof, and having an external diameter which is less than an inner diameter of the first tube, the inner tube being coaxially receivable in the first tube,
wherein the centre shaft is coaxially receivable in a bore of the first tube with the transverse formation locating in diametrically opposed notches of a head of the screw and wherein the inner tube is coaxially receivable between the centre shaft and the first tube and the external thread cooperates with a complementary internal thread in the first tube to bear onto and lock the transverse formation of the centre shaft in the diametrically opposed notches,
a second tower which is mountable on a second surgical screw;
a link extending between the first and second towers; and
at least a first elongate retractor element for at least one of muscle, tissue and nerve structures and which at least first elongate retractor element is movably mountable on the link.

US Pat. No. 10,111,646

SURGICAL INSTRUMENT TO ASSESS TISSUE CHARACTERISTICS

Warsaw Orthopedic, Inc., ...

1. A method of removing a bone lesion from a bone, the method comprising:placing a hand-held ultrasonic device at least proximate a surface of the bone lesion, the hand-held ultrasonic device defining a longitudinal axis and including multiple emitting transducers and a dedicated receiving transducer, each of the multiple emitting transducers being configured to emit at least one acoustic signal;
emitting, with each emitting transducer of the multiple emitting transducers, the at least one acoustic signal into the bone lesion, each of the at least one acoustic signals being reflected by a boundary of the bone lesion, each of the reflected acoustic signals defining an echo;
separately detecting, with the dedicated receiving transducer, each of the echoes correlating to each of the at least one acoustic signals;
determining a time delay for each of the detected echoes, each of the time delays being calculated from the time of the emitting of each of the at least one acoustic signals and the detecting of each of the echoes;
assuming a speed for each of the at least one acoustic signals in the bone lesion;
calculating boundaries of the bone lesion by calculating depths thereof based on at least the determining of the time delays and the assumed speeds;
calculating an approximate volume of the bone lesion based on the calculating of the boundaries of the bone lesion and comparing the boundaries to one or more known geometric shapes of known volume; and
based on the calculated approximate volume, debriding the bone lesion to produce a cavity in the bone substantially free of the bone lesion.

US Pat. No. 10,111,645

PERCUTANEOUS, ULTRASOUND-GUIDED INTRODUCTION OF MEDICAL DEVICES

Muffin Incorporated, Wes...

1. A system for delivering a vascular filter to a target site in a patient, the system comprising:a sheath introducible through a percutaneous access site of the patient, the sheath having an inner lumen and a distal tip, the sheath having an echogenic marker located proximate the distal tip and a first series of visible indicia occurring along a first longitudinal region of the sheath, the first longitudinal region positioned to include a location aligned with a reference point external of the percutaneous access site when the distal tip of the sheath is at the target site;
an intravascular ultrasound device configured for slidable receipt through the inner lumen of the sheath and having an intravascular ultrasound probe in a distal region thereof for generating an ultrasound image signal for identifying the target site;
a filter introducer configured for slidable receipt through the inner lumen of the sheath, the filter introducer including a filter delivery instrument and a vascular filter carried by the filter delivery instrument;
wherein the vascular filter includes a first echogenic marker, and a second echogenic marker longitudinally spaced a distance from the first echogenic marker; and
wherein the filter includes a hub and plurality of struts emanating from the hub, and wherein the first echogenic marker is provided on the hub.

US Pat. No. 10,111,644

METHOD OF COHERENT FLOW IMAGING USING SYNTHETIC TRANSMIT FOCUSING AND ACOUSTIC RECIPROCITY

The Board of Trustees of ...

1. A method for acoustic imaging, the method comprising:providing an acoustic imaging system including an acoustic transducer array and a processor;
emitting collimated acoustic radiation from the acoustic transducer array at a target at three or more distinct incidence angles;
receiving scattered acoustic radiation from the target with the acoustic transducer array;
determining acoustic images of the target from the scattered acoustic radiation corresponding to each of the three or more incidence angles;
computing an angular coherence image with the processor by
i) averaging the acoustic images vs. angle to estimate an angular coherence function at each spatial point of the acoustic images;
ii) integrating the angular coherence function over a predetermined angular range to provide the angular coherence image;
providing the angular coherence image as an output.

US Pat. No. 10,111,643

CARDIAC MONITOR SYSTEM AND METHOD FOR HOME AND TELEMEDICINE APPLICATION

Medtronic Vascular, Inc.,...

1. A system for detecting aortic stenosis comprising:a monitoring device configured to be coupled to a patient, the monitoring device including a heart sound sensor configured to detect heart sounds of the patient, and a signal processor; and
a processor configured to
receive a signal representative of the detected heart sounds from the signal processor and process the signal representative of detected heart sounds to determine tested values of at least one of,
peak frequencies of a first heart sound, a second heart sound, and a third heart sound of the patient, wherein the first heart sound is detected at closure of a mitral valve of the patient, the second heart sound is detected at the closure of an aortic valve and a pulmonary valve of the patient, and the third heart sound is detected at passive diastolic filling of ventricles of the patient,
a ratio of a first time period from the second heart sound in a first cardiac cycle to the first heart sound in a second cardiac cycle and a second time period from the first heart sound in the second cardiac cycle to the second heart sound in the second cardiac cycle, and
a heart beat cycle period including a systole period and a diastole period, and
compare at least one of the tested values to corresponding baseline values of the peak frequencies, the ratio, and the heart beat cycle periods stored in memory.

US Pat. No. 10,111,642

POSITIONING OF A MOBILE X-RAY DETECTOR

Siemens Healthcare GmbH, ...

1. A positioning device for a mobile x-ray detector, comprising:at least one device selected from the group consisting of at least one marker and at least one sensor for determining a position of the positioning device;
a number of connection elements for establishing a mechanical connection between the positioning device and the mobile x-ray detector; and
an arm which is movable from a first position to a second position and back again, said arm having a free end at which at least one of said marker or said sensor is disposed, wherein at least one of said marker or said sensor has a greater distance from the mobile x-ray detector in the second position of said arm than in the first position of the arm.

US Pat. No. 10,111,641

RADIOGRAPHIC IMAGING APPARATUS AND METHOD OF CONTROLLING THE SAME

SAMSUNG ELECTRONICS CO., ...

1. A radiographic imaging apparatus, comprising:a radiographic image generator;
a motor configured to move the radiographic image generator and to output, as a feedback signal, information which relates to at least one from among a driving speed and a position of the motor;
a guide rail to which the motor is connected via a post frame, the guide rail being fixably attached to a ceiling, and the radiographic image generator being coupled to the post frame by a rotary joint that is configured to enable the radiographic image generator to rotate in each of a first direction about a first axis that is orthogonal to the ceiling and a second direction about a second axis that is orthogonal to the first axis and parallel to the ceiling; and
a controller configured to calculate a disturbance applied to the radiographic image generator by using the feedback signal output from the motor and a control signal for driving the motor, and to drive the motor based on the calculated disturbance,
wherein the controller is further configured to calculate the disturbance by subtracting the control signal for driving the motor from the feedback signal output from the motor.

US Pat. No. 10,111,640

RADIATION IMAGING SYSTEM, RADIATION IMAGING APPARATUS, RADIATION IMAGING METHOD, AND STORAGE MEDIUM

CANON KABUSHIKI KAISHA, ...

1. A radiation imaging system comprising:an imaging unit configured to transfer a radiation image generated based on radiation to a console;
a setting unit configured to set a first interrupt determination time for determining an interrupt of transfer of reduced image data of the radiation image and a second interrupt determination time for determining an interrupt of transfer of whole image data of the radiation image data; and
a control unit configured to interrupt the transfer of the reduced image data in a case where an elapsed time taken to transfer the radiation image exceeds the first interrupt determination time and to interrupt the transfer of the whole image data in a case where an elapsed time taken to transfer the radiation image exceeds the second interrupt determination time.

US Pat. No. 10,111,638

APPARATUS AND METHOD FOR REGISTRATION AND REPROJECTION-BASED MATERIAL DECOMPOSITION FOR SPECTRALLY RESOLVED COMPUTED TOMOGRAPHY

Toshiba Medical Systems C...

1. An apparatus, comprising:processing circuitry configured to
obtain first projection data representing an intensity of first radiation incident at a plurality of detector elements, the first radiation having a first photon energy;
obtain second projection data representing an intensity of second radiation incident at the plurality of detector elements, the second radiation having a second photon energy;
register a reconstructed image of the second projection data to a reconstructed image of the first projection data;
update the second projection data using the registered reconstructed image of the second projection data; and
perform material decomposition using the updated second projection data and an updated first projection data or the first projection data.

US Pat. No. 10,111,637

SYSTEMS AND METHODS FOR EMULATING DEXA SCORES BASED ON CT IMAGES

Zebra Medical Vision Ltd....

1. A computerized method for estimating a DEXA score from three dimensional (3D) computed tomography (CT) imaging data, comprising:receiving 3D imaging data of a CT scan of a body of a patient containing at least a 3D bone portion;
segmenting the 3D bone portion from the 3D imaging data of the CT scan;
computing at least one grade for the 3D bone portion based on pixel associated values from the 3D bone portion;
correlating the at least one grade of the 3D bone portion with at least one score representing a relation to bone density values in a population obtained based on a dual-energy X-ray absorptiometry (DEXA) scan,
wherein the at least one grade for the 3D bone portion is computed from a calculation of sub-grades performed for each one or a set of pixels having at least one of a common medial-lateral axial coordinate and a common cranial-caudal axial coordinate along a dorsal-ventral axis of a volume representation of the 3D imaging data of the CT scan; and
presenting the at least one score correlated to the least one grade on a presentation unit for diagnosis of at least one of bone mineral density (BMD), osteoporosis, and osteopenia.

US Pat. No. 10,111,636

SYNTHETIC DATA-DRIVEN HEMODYNAMIC DETERMINATION IN MEDICAL IMAGING

Siemens Healthcare GmbH, ...

1. A method for hemodynamic determination in medical imaging, the method comprising:acquiring medical scan data representing an anatomical structure of a patient;
extracting a set of features from the medical scan data;
inputting, by a processor, the features to a machine-trained classifier, the machine trained classifier trained from synthetic data not specific to any patients; and
outputting, by the processor with application of the machine-trained classifier to the features, a hemodynamic metric.

US Pat. No. 10,111,635

IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, AND STORAGE MEDIUM

Toshiba Medical Systems C...

1. An image processing apparatus, comprising:storage circuitry to store therein a fluid resistance database correlating templates of vascular shapes with fluid resistances; and
processing circuitry configured to:
extract, from three-dimensional image data in which a blood vessel of a subject is rendered, vascular shape data representing a shape of the blood vessel;
divide the vascular shape data into a plurality of segments;
perform pattern matching between each of the segments of the vascular shape data and the templates included in the fluid resistance database to obtain respective fluid resistances;
form, based on the obtained fluid resistances, a vascular network expressing one-dimensional fluid resistances; and
perform fluid analysis by using the formed vascular network to derive a functional index related to a blood circulation state in the blood vessel of the subject.

US Pat. No. 10,111,634

NUCLEAR MEDICINE DIAGNOSTIC APPARATUS, DIAGNOSTIC IMAGING APPARATUS, AND IMAGE PROCESSING METHOD

Toshiba Medical Systems C...

10. An image processing method, comprising:counting radiation emitted from radioisotopes in an imaging region of an object;
setting a region of interest (ROI) in the imaging region; and
providing a table associating count values of the counted radiation and pixel values used for display pixels for the ROI;
changing an average and the range of the pixel values in the table in accordance with an average and a variance of the count values of the display pixels corresponding to the ROI, respectively, and determining an association between the count values and the pixel values of the display pixels corresponding to the ROI by using the changed table; and
generating an image of the ROI, wherein generating the image comprises calculating the pixel values of the respective display pixels corresponding to the ROI based on the determined association between the count values and the pixel values.

US Pat. No. 10,111,633

LOCAL FFR ESTIMATION AND VISUALISATION FOR IMPROVED FUNCTIONAL STENOSIS ANALYSIS

KONINKLIJKE PHILIPS N.V.,...

1. An image processing system, comprising:an input port for receiving at least one image including a projection view of an object of interest;
a segmenter configured to segment the image to obtain an object segmentation for the object as per the projection view;
a partitioner configured to partition the segmentation into components;
an adaptation unit configured to adapt at least one of a plurality of local effect transfer functions to a local geometry of the object as recorded in respective ones of the components to obtain a plurality of global effect transfer functions;
a combiner configured to combine the plurality of global effect transfer functions into a composite transfer function for the object;
an evaluator configured to compute from the composite transfer function a fractional flow reserve (FFR) estimate for a fluid flowing through the object, wherein the evaluator operates to compute a range of FFR estimates by varying physical and physiological parameters;
a visualizer configured to render for display on a display unit the range of FFR estimates as a function of at least one the physical and physiological parameters; and
the display unit operating to display the range of FFR estimates in their functional dependence,
wherein the physical and physiological parameters include at least one of pressure and flow rate, and wherein the range of FFR estimates is displayed as a function of the at least one of pressure and flow rate.

US Pat. No. 10,111,632

SYSTEM AND METHOD FOR BREAST CANCER DETECTION IN X-RAY IMAGES

Siemens Healthcare GmbH, ...

1. A method for breast cancer detection with an x-ray scanner, scanner, the method comprising:scanning a patient with the x-ray scanner, the scanning providing a frame of data representing breast tissue in the patient;
classifying patches of the frame of data as of interest or not based on intensity;
determining a probability of breast cancer for the patches that are of interest using a deep learnt regression at least partially trained on non-x-ray data, the probability not determined for the patches not of interest, the determining comprising inputting the patches that are of interest into the deep learnt regression, the deep regression outputting feature values;
classifying the patches with the probability over a threshold using a machine-learnt classifier and not classifying the patches with the probability below the threshold; and
displaying an indication of breast cancer for the patient based on an output of the classifying using the machine-learnt classifier.

US Pat. No. 10,111,631

SYSTEM AND METHOD FOR GENERATING AND DISPLAYING TOMOSYNTHESIS IMAGE SLABS

HOLOGIC, INC., Marlborou...

1. A system for processing breast tissue images, comprising:an image processing computer; and
a user interface operatively coupled to the image processing computer,
wherein the image processing computer is configured to
obtain image data of breast tissue,
process the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, and
process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices, wherein the respective 2D synthesized image does not correspond to an image that was acquired during imaging of the breast tissue.

US Pat. No. 10,111,630

X-RAY DIAGNOSIS APPARATUS

Toshiba Medical Systems C...

1. An X-ray diagnosis apparatus, comprising:a holding device configured to be movable by a moving operation and hold an X-ray tube;
a route specify unit configured to specify a movement route;
a drive unit configured to drive the holding device along the specified movement route;
an operation direction detector configured to detect an operation direction, the operation direction being a direction of the moving operation that the holding device has received; and
a drive controller configured to control the drive unit to stop a driving force when the operation direction differs from a movement direction, the movement direction being a direction of the movement route,
wherein the holding device is further configured to receive the moving operation when the drive controller controls the drive unit to stop driving.

US Pat. No. 10,111,629

IMAGING STAND

SAMSUNG ELECTRONICS CO., ...

1. An imaging stand, comprising:a frame;
a plate provided to be movable along the frame and having a first plate and a second plate; and
a fixing device provided on a rear surface of the plate and configured to have elastic force pressing the frame when fixed in the frame, the fixing device having a first fixing device provided on a rear surface of the first plate and a second fixing device provided on a rear surface of the second plate,
wherein the first fixing device comprises a connecting part mounted on the rear surface of the first plate and an opening facing the connecting part of the first fixing device, and
the second fixing device comprises a connecting part mounted on the rear surface of the second plate and an opening facing the connecting part of the second fixing device,
the first fixing device and the second fixing device are disposed parallel with each other also that the opening of the first fixing device and the opening of the second fixing device face toward the same direction.

US Pat. No. 10,111,628

X-RAY IMAGING APPARATUS AND METHOD FOR MARKING A LOCATION OF A SURGICAL TOOL ON A DISPLAYED IMAGE

SAMSUNG ELECTRONICS CO., ...

1. An X-ray imaging apparatus comprising:an X-ray generator configured to direct X-rays to a subject;
an X-ray detector that detects X-rays generated by the X-ray generator and outputs image data;
an image processor that receives the image data output by the X-ray detector and produces a plurality of 2-dimensional (2D) images of the subject, wherein the image processor is configured to:
generate a 3-Dimensional (3D) image of the subject from the plurality of 2D images of the subject,
generate a 3D blood vessel image by extracting blood vessel information from the 3D image of the subject,
generate a 2D blood vessel image by projecting the 3D blood vessel image onto a 2D plane,
overlap the 2D blood vessel image with a 2D fluoroscopy image to acquire a 2D roadmap image corresponding to a first position,
detect a location of a surgical tool from the 2D roadmap image corresponding to the first position,
detect a blood vessel corresponding to the location of the surgical tool from the 3D blood vessel image,
mark the location of the surgical tool with an identifier in the detected blood vessel; and
a display configured to display the 2D roadmap image, the detected blood vessel, and the identifier.

US Pat. No. 10,111,627

MEDICAL IMAGE PROCESSING APPARATUS

TOSHIBA MEDICAL SYSTEMS C...

1. A radiation diagnostic apparatus comprising:an X-ray tube;
a plurality of radiation detecting elements configured to detect X-rays radiated from the X-ray tube;
a plurality of signal processing substrates configured to perform processing including at least A/D conversion processing on outputted signals of the plurality of radiation detecting elements and to output processed signals as the outputted signals after being subjected to the processing including at least A/D conversion; and
processing circuitry configured to
identify a non-observing element or a non-observing substrate based on information on an imaging region included in imaging conditions of an object, the non-observing element being a radiation detecting element of the plurality of radiation detecting elements which corresponds to a region other than the imaging region, and the non-observing substrate being a signal processing substrate of the plurality of signal processing substrates which corresponds to the non-observing element, and
control an operation of the non-observing element or an operation of the non-observing substrate in imaging under the imaging conditions.

US Pat. No. 10,111,626

X-RAY CT APPARATUS

Toshiba Medical Systems C...

1. An X-ray computed tomography (CT) apparatus comprising:collection circuitry configured to collect a signal derived from X-rays emitted from an X-ray tube and transmitted through a subject;
control circuitry configured to calculate a value of tube current to be supplied to the X-ray tube in a main scan, based on a first image acquired through a first reconstruction process, the first reconstruction process using the signal and a first image-processing filter, the signal being collected by the collection circuitry in a localizer scan; and
image generation circuitry configured to generate a second image as a localizer image through a second reconstruction process, the second reconstruction process using the signal and a second image-processing filter, the signal being collected by the collection circuitry in the localizer scan.

US Pat. No. 10,111,625

BIOPSY APPARATUS AND OPERATION METHOD THEREOF

FUJIFILM Corporation, To...

1. A biopsy apparatus comprising:a radiation source for irradiating radiation toward a subject to be examined from a tube;
a radiation detector for detecting radiation which has been irradiated from the radiation source and passed through the subject so as to generate a radiographic image;
a stereotactic image generator for generating a stereotactic image, which consists of two radiographic images generated by the radiation detector and is represented by a stereotactic coordinate system, by irradiating radiation from the tube disposed at two stereotactic tube positions each having a different angle relative to the subject;
a tomosynthesis image generator for generating a tomosynthesis image, which is represented by a tomosynthesis coordinate system, by irradiating radiation from the tube disposed at a plurality of tomosynthesis tube positions each having a different angle relative to the subject and performing reconstruction of a plurality of tomographic images from a plurality of radiographic images generated by the radiation detector;
a biopsy needle driver for driving a biopsy needle based on a biopsy coordinate system calibrated with respect to the stereotactic coordinate system so as to insert the biopsy needle into the subject; and
a processor configured to:
identify a position of a target designated based on the tomosynthesis image as a first designated position; and
obtain two projection positions by virtually projecting the first designated position to the image detector from two calibrated-stereotactic tube positions which have been calibrated into the tomosynthesis coordinate system, and converting the first designated position into a second designated position in the stereotactic coordinate system based on the stereotactic tube positions and the projection positions.

US Pat. No. 10,111,624

MEASURING ELECTRODE IMPEDANCE IN AN IMPEDANCE MEASUREMENT CIRCUIT

TEXAS INSTRUMENTS INCORPO...

1. A circuit comprising:an excitation source;
a sense circuit;
a first electrode;
a second electrode;
a first switch coupled between a terminal of the excitation source and the first electrode;
a second switch coupled between the first electrode and a terminal of the sense circuit;
a third switch coupled between the terminal of the excitation source and the second electrode; and
a fourth switch coupled between the second electrode and the terminal of the sense circuit,
wherein the sense circuit is configured to close both the first switch and the second switch during measurement of an impedance.

US Pat. No. 10,111,623

MULTI-ELECTRODE MAPPING CATHETER

X-RHYTHM, LLC, Beachwood...

1. A multi-electrode mapping catheter for endocardial contact mapping of a heart chamber of a patient, the mapping catheter comprising:a flexible elongated catheter shaft having a proximal end, an outer surface, and a distal end;
an expandable mapping basket located at the distal end of the catheter shaft, the expandable mapping basket including a plurality of spaced-apart flexible splines, each flexible spline including a flex circuit affixed to a support layer made from a flexible substrate material, the flexible substrate material being resilient and shaped to bow outwardly to bias the basket to an expanded configuration for deployment for mapping by which the expandable mapping basket maintains the flex circuit in contact with the wall of the heart while accommodating wall motion of the beating heart;
wherein each flex circuit includes a first layer having a plurality of electrodes formed thereon and a metallic layer, the metallic layer including a plurality of conductors, each electrode of the first layer being connected to a separate conductor of the metallic layer, wherein the electrodes are located so as to be at an outer surface of the flex circuit and in contact with a wall of the heart chamber when deployed; and
wherein each flex circuit comprises a continuous single-piece electrical conductor that is directly in electrical contact with an electrode and that is mounted to the outer surface of the catheter shaft and extends along the entire elongated catheter shaft without interruption and without interim connection to any other electrical device and which terminates at the proximal end of the catheter shaft to thereby directly communicate signals received at the respective electrode to the proximal end of the catheter shaft.

US Pat. No. 10,111,622

EVALUATION OF THE QUALITY OF ELECTRODE CONTACT WITH A SKIN SURFACE

WELCH ALLYN, INC., Skane...

1. A system comprising:an injection, a sense and a return skin-contacting electrode;
a current source, wherein the current source applies an AC test current to the injection skin-contacting electrode, the AC test current having a first polarity and a first magnitude,
a driven return coupled between the sense skin-contacting electrode and the return skin-contacting electrode, wherein the driven return accepts a return of the AC test current through the return skin-contacting electrode, wherein the driven return operates to keep a voltage at the sense skin contacting electrode centered at an isolated ground potential, and wherein the driven return generates a return current that is supplied to the injection skin-contacting electrode, the return current having a polarity opposite to the first polarity;
a processor, the processor executing instructions for performance of a simultaneous test to determine the quality of skin contact of both the injection and return skin-contacting electrodes, wherein execution of the instructions cause the processor to:
determine both a first differential voltage between the injection and sense skin-contacting electrodes and a second differential voltage between the sense and return skin-contacting electrodes after application of the AC test current and the return current; and
determine a first and second magnitude of a contact impedance for each of the injection and return skin-contacting electrodes, respectively, based on the first and second differential voltages, wherein the first and second magnitudes of contact impedance are representative of a quality of skin contact of the injection and return skin-contacting electrodes, respectively.

US Pat. No. 10,111,620

ENHANCED MOTION TRACKING USING TRANSPORTABLE INERTIAL SENSORS TO DETERMINE THAT A FRAME OF REFERENCE IS ESTABLISHED

MICROSOFT TECHNOLOGY LICE...

1. An apparatus comprising:a first inertial sensor mounted on a portable device of a user;
a second inertial sensor mounted on a tracking device of the user being carried by a moving platform; and
a computer-readable storage medium storing executable instructions configured to:
receive, from the portable device, input that indicates the portable device is affixed or secured to the moving platform,
receive, from the first inertial sensor, a signal useable to determine an established frame of reference based at least in part on the portable device being affixed or secured to the moving platform,
receive, from the second inertial sensor, a signal useable to determine movement of the tracking device within the established frame of reference;
provide a notification,
receive a response to the notification, and
based on the response indicating an acceptance, process the signal received from the second inertial sensor and the signal received from the first inertial sensor to determine the movement of the tracking device within the established frame of reference.

US Pat. No. 10,111,619

SMART SPORTS PROTECTIVE APPARATUS INCLUDING USER DATA COLLECTING CIRCUIT

1. A smart sports protective apparatus, comprising:a base body device for covering at least a part of a user's body to relieve an impact of an external force to at least the part of the user's body when the user is playing sports;
a circuit device for collecting user data, including the user's biological data, motion status data, and body gesture data, from the user in real time when the user is playing sports, at least a part of the circuit device being arranged inside the base body device; and
a power supply device for supplying an electric power to the circuit device, the power supply device being arranged inside the base body device, the circuit device and the power supply device being formed integrally and being tiled in the base body device,
the circuit device comprising:
a data collecting unit for collecting the user data, and the data collecting unit including
a biosensing module for collecting the user's biological data,
a gesture sensing module for collecting the user's body gesture data, and
a motion sensing module for collecting the user's motion status data; and
a first processing unit for controlling the collecting operations of the data collecting unit,
at least a part of the biosensing module being arranged on an inner surface of the base body device contacting with the user's body, and the biosensing module comprising at least one of:
a heart rate sensor for detecting data of a real-time heart rate of the user,
an electrocardio sensor for detecting data of a real-time electrocardo of the user,
a pulse sensor for detecting data of a real-time pulse of the user,
a blood oxygen sensor for detecting data of a real-time blood oxygen of the user,
a body temperature sensor for detecting data of a real-time body temperature of the user,
a myoeletricity sensor for detecting data of a real-time myoeletricity of the user, and
a blood pressure sensor for detecting data of a real-time blood pressure of the user,
at least one of the heart rate sensor, the electrocardio sensor, the pulse sensor, and the blood oxygen sensor comprising
an optical transceiver which, when the base body device covers at least the part of the user's body, emits and receives light in a closed space formed by the base body device and at least the part of the user's body without being influenced by external light,
the circuit device further comprising:
a first wireless communication unit for transmitting the user data to a mobile terminal wirelessly;
a second wireless communication unit for transmitting the user data to a server wirelessly via a base station apparatus, at least a part of the second wireless communication unit being arranged not to be blocked by insulators in the smart sports protective apparatus; and
a second processing unit for controlling the wireless transmission operation of the second wireless communication unit.

US Pat. No. 10,111,618

DUAL PURPOSE WEARABLE PATCH FOR MEASUREMENT AND TREATMENT

VivaLnk, Inc., Campbell,...

1. A dual purpose wearable patch, comprising:a stretchable and permeable substrate;
a sensing unit mounted in the stretchable and permeable substrate, wherein the sensing unit includes a bottom portion adapted to be in direct contact with a user's skin, wherein the sensing unit comprises a temperature sensor in thermal contact with the bottom portion to conduct a measurement of a user to produce a measurement signal;
one or more electrodes respectively attached to the stretchable and permeable substrate, wherein the one or more electrodes are configured to be in electrical contact with the user's skin and are configured to apply a voltage across the user's body;
a circuit substrate on the stretchable and permeable substrate, wherein the circuit substrate comprises a circuit electrically connected with the one or more electrodes and the sensing unit; and
a semiconductor chip mounted on the circuit substrate and in connection with the circuit, wherein the semiconductor chip is configured to receive the measurement signal from the sensing unit, wherein the semiconductor chip is configured to produce a treatment control signal to control the one or more electrodes to apply a voltage across the user's body.

US Pat. No. 10,111,617

SYSTEMS AND METHODS FOR EEG MONITORING

Covidien LP, Mansfield, ...

1. A medical monitoring system, comprising:an electroencephalography (EEG) sensor array comprising a plurality of electrodes configured for EEG monitoring, wherein the plurality of electrodes are configured to be disposed about a patient's head, and wherein the plurality of electrodes comprise a ground electrode, a reference electrode, and a plurality of sensing electrodes; and
an EEG monitor operatively coupled to the EEG sensor array, wherein the EEG monitor comprises:
input circuitry configured to receive EEG signals from the plurality of sensing electrodes;
a processor configured to:
determine a plurality of depth of anesthesia indices based at least in part on the EEG signals, wherein the depth of anesthesia indices comprise bispectral indices; and
generate a topographic color map of the depth of anesthesia indices based on a color scale, wherein the color scale comprises a predetermined set of colors, wherein each color of the predetermined set of colors represents a predetermined depth of anesthesia index; and
a display configured to display the topographic color map;
wherein the EEG monitor is configured to receive a user selection of one or more regions of the patient's head to monitor, wherein the display is configured to display an anesthesia index for each of the one or more regions, and wherein the processor is configured to determine a correlation between depth of anesthesia indices associated with a first region of the patient's head and depth of anesthesia indices associated with a second region of the patient's head, and wherein the processor is configured to detect a clinically adverse event based at least in part upon the correlation.

US Pat. No. 10,111,616

APPARATUS, METHOD AND COMPUTER ACCESSIBLE MEDIUM FOR MONITORING SLEEP QUALITY AND APPARATUS THEREOF

NEUSOFT XIKANG ALPS (SHEN...

1. A method for monitoring sleep quality of a user, comprising:with a radio frequency (RF) sensor located in a specifically-programmed computer, collecting RF body movement signals of a user during sleep;
with the specifically-programmed computer, calculating body movement energy of a preset time-slot, based on the RF body movement signals collected during the preset time-slot, wherein the preset time-slot is one of a plurality of preset time-slots comprised in a preset estimation time-span;
with the programmed computer, calculating an estimation threshold of the preset estimation time-span, based on an average value of the body movement energy of the plurality of preset time-slots which are comprised in the preset estimation time-span;
with the programmed computer, determining a sleep state of the user in the preset time-slot based on a comparison between the body movement energy of the preset time-slot and the estimation threshold of the preset estimation time-span, wherein the determining of the sleep state includes determining the sleep state that is at least one of a stage of deep sleep, a stage of light sleep, a stage of intermediate sleep or an awake stage; and
monitoring the sleep quality of the user based on the determined sleep state of the user.

US Pat. No. 10,111,615

SLEEP SCORING BASED ON PHYSIOLOGICAL INFORMATION

Fitbit, Inc., San Franci...

1. A method of assessing sleep quality of a user at an electronic device having one or more processors and a non-transitory computer readable storage medium, the method comprising:receiving one or more signals indicating an attempt by the user to fall asleep;
receiving physiological information associated with the user including at least one sleeping heart rate, the physiological information generated by one or more physiological sensors;
determining respective values for one or more sleep quality metrics based at least in part on the physiological information and at least one wakeful resting heart rate of the user; and
determining a unified score for sleep quality of the user, based at least in part on the respective values of the one or more sleep quality metrics.

US Pat. No. 10,111,614

APPARATUS AND METHOD FOR DETECTING NIR FLUORESCENCE AT SENTINEL LYMPH NODE

INTHESMART CO. LTD., Seo...

6. A method for detecting near-infrared (NIR) fluorescence at a sentinel lymph node (SLN), the method comprising;irradiating white light and near-infrared (NIR) excitation light onto an object;
collecting white reflection light reflected off the object when the white is irradiated on the object and near-infrared (NIR) fluorescence reflected off the object when the near-infrared (NIR) excitation light is irradiated onto the object;
processing the white reflection light and the near-infrared (NIR) fluorescence as a visible (VIS) reflection light image signal and a near-infrared (NIR) fluorescence image signal, respectively;
implementing the visible (VIS) reflection light image signal with red (R), green (G) and blue (B); and
controlling a frame rate of the near-infrared (NIR) fluorescence image signal to be lowered than a frame rate of a frame timing plus while maintaining the visible (VIS) reflection light image signal with red (R), green (G) and blue (B).

US Pat. No. 10,111,613

METHODS FOR DATA RETENTION IN AN IMPLANTABLE MEDICAL DEVICE

MEDTRONIC, INC., Minneap...

1. A method for retaining physiologic data in an implantable medical device, wherein the physiologic data comprises an old data record being stored in a first data structure and having an old priority index, the method comprising:sensing a physiologic signal at the implantable medical device with a sensor and converting the physiological signal to physiologic data;
(A) receiving a new data record that includes physiologic data obtained for an event;
(B) determining a new priority index of the new data record;
(C) replacing at least a portion of the old data record with at least a portion of the new data record in the first data structure;
(D) if the old priority index exceeds a threshold criterion, storing at least a portion of the old data record in a second data structure, wherein the threshold criterion is pre-determined relative to creation of the old and new data records so as to be determined independently from determining which priority indexes to associate to the old and new data records of the first and second data structures, wherein the first data structure comprises a new data pointer configured to point to one of a plurality of data entries, and, after a data record is stored in the one of a plurality of data entries, point to another data entry where the next incoming data record is to be stored in the first data structure, and wherein the second data structure is distinct from the first data structure;
(E) determining the old priority index by determining an old severity level that is associated with the old data record;
(F) determining a new severity level that is associated with the new data record, a new priority index of the new data record based on the new severity level;
(G) evaluating the new severity level by a processing device of the medical device to control a start of therapy; and
(H) using a therapy device of the medical device to provide the therapy.

US Pat. No. 10,111,611

PERSONAL EMOTIONAL PROFILE GENERATION

Affectiva, Inc., Boston,...

1. A computer-implemented method for mental state analysis comprising:obtaining mental state data from an individual, wherein the mental state data is extracted, using one or more processors, from facial images of an individual captured as they respond to stimuli;
analyzing the mental state data extracted from facial images to produce mental state information;
correlating the mental state information of the individual with mental state information from a plurality of people, wherein the mental state information from the plurality of people is determined as a function of at least one historical environmental condition measured from ambient conditions affecting at least one of the plurality of people and stored as historical contextual information;
categorizing, using one or more processors, the individual with others from the plurality of people based on the correlating and a rate of change of a plurality of expressions of the individual, wherein the rate of change is evaluated during exposure to specific stimuli and wherein the categorizing is part of a profile;
determining at least one recent environmental condition by measuring an ambient condition affecting the individual during the exposure to specific stimuli and storing the measurement as recent contextual information; and
predicting a future reaction to a stimulus, based on the profile, the historical contextual information, and the recent contextual information.

US Pat. No. 10,111,610

MICROSCALE PLASMA SEPARATOR

Wainamics, Inc., Pleasan...

1. A device for separating plasma from whole blood, the device comprising:(a) a sample collection receptacle with at least one port, the sample collection receptacle capable of holding a predetermined volume of a sample of whole blood drawn through a port;
(b) a filter chamber having an inlet and an outlet, and containing at least one filter capable of separating plasma from blood cells as sample passes from an inlet side to an outlet side of the at least one filter whenever the filter chamber is placed in fluid communication with a port of the sample collection receptacle; and
(c) a manually driven pump operationally associated with the sample collection receptacle and filter chamber for (i) drawing a predetermined volume of sample into the sample collection receptacle by a first user action and (ii) driving by a spring-drive mechanism or an elastomeric bladder the predetermined volume at a substantially constant linear flow under a pressure not exceeding 2 psi from the sample collection receptacle through the filter chamber and the outlet of the filter chamber by a second user action.

US Pat. No. 10,111,609

METHOD FOR DETECTING A MALFUNCTION OF A SENSOR FOR MEASURING AN ANALYTE CONCENTRATION IN VIVO

ROCHE DIABETES CARE, INC....

1. A method for detecting a malfunction of a sensor for measuring an analyte concentration in vivo, comprising:producing a series of measuring signals, by means of the sensor;
determining successively a value of a noise parameter from the measuring signals, the noise parameter indicating how severely the measurement is impaired by interference signals;
determining the rate of change of the values of the noise parameter by calculating a time derivative of the noise parameter, wherein the rate of change of the noise parameter is determined on a smoothened series of values of the noise parameter; and
analyzing the rate of change of the noise parameter in order to detect a malfunction,
wherein in calculating the value of the noise parameter it is determined which portion of a measuring value is based on the interference signals such that a given measuring value is the sum of a useful signal that corresponds to the analyte concentration and the interference signal, and
wherein a recursive filter is used to separate a noise portion from the useful portion of the measurement signal.

US Pat. No. 10,111,607

METHOD AND APPARATUS FOR CONTROLLING LESION SIZE IN CATHETER-BASED ABLATION TREATMENT

1. A system for visualizing lesions on target tissue, the system comprising a data acquisition and processing unit configured to:receive signals from a force sensor of an elongated flexible catheter comprising an ablation head, said force sensor signals being in reaction to forces exerted against said ablation head by said target tissue;
produce a sequence of contact force values based on said force sensor signals acquired over a time period of energization of said ablation head;
determine in real time a force-time integral based on said sequence of contact forces;
characterize a lesion based on said force-time integral; and
generate for display a visualization representing said characterization of said lesion.

US Pat. No. 10,111,606

INTEGRATED CONDENSER FOR COLLECTING DROPLETS

The Regents of the Univer...

1. An integrated condenser, comprising:a substrate; and
a sampler surface disposed on the substrate configured to receive a gas-phase sample, wherein the sampler surface further comprises:
an outer surface region configured to:
facilitate condensing at least a portion of the received gas-phase sample into liquid-phase droplets on the sampler surface; and
facilitate aggregating and moving the condensed droplets radially toward a center of the sampler surface;
wherein the outer surface region is micro-patterned to create a wettability gradient which is distributed axisymmetrically,
wherein the micro-pattern comprises a set of micro-patterned concentric rings,
wherein a given micro patterned concentric ring of the set of micro-patterned concentric rings comprises a set of radially oriented wall-groove pairs, and
wherein the number of wall-groove pairs in the given micro-patterned concentric ring increases from the outermost ring toward the innermost ring; and
an inner surface region within the outer surface region, wherein the inner surface region is configured to receive the condensed droplets collected by the outer surface region.