US Pat. No. 10,428,185

THERMOPLASTIC ELASTOMER HYDROGELS

Colorado State University...

1. A block copolymer hydrogel, comprising:a glass formed from a dry blend comprising polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS; and
a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO—SOS by weight, the liquid medium comprising at least one room-temperature ionic liquid (RTIL);
the block copolymer hydrogel having a fatigue resistance to at least 500,000 compression cycles, wherein the compression cycles operate with at least 12% compression at a frequency of about 1 Hz, and the compression cycles operate with at least 50% compression at least every eleventh cycle and wherein the fatigue resistance is characterized by a modulus recoverable to at least 80% of its value before the compression cycles were run.

US Pat. No. 10,428,181

POROUS CROSS-LINKED PARTIALLY ALIPHATIC POLYIMIDE NETWORKS

OHIO AEROSPACE INSTITUTE,...

1. A porous cross-linked partially aliphatic polyimide network comprising a polyamic acid oligomer that (i) comprises a repeating unit of a dianhydride and a diamine and terminal functional groups, (ii) has an average degree of polymerization of 10 to 70, (iii) has been cross-linked via a cross-linking agent, comprising three or more cross-linking groups, at a balanced stoichiometry of the cross-linking groups to the terminal functional groups, and (iv) has been chemically imidized to yield the porous cross-linked polyimide network, wherein the polyimide network is partially aliphatic based on one or both of the following:(a) the diamine comprises: (i) a first diamine at 5 to 95% (mol %) and (ii) a second diamine at 5 to 95% (mol %), wherein (1) the first diamine comprises a first diamine linear aliphatic backbone chain comprising carbon atoms and optionally one or more oxygen atoms therein, extending a length of 3 to 30 atoms, and having a ratio of carbon:oxygen of 2:1 to 3:0, and (2) the second diamine does not comprise any linear aliphatic backbone chain extending a length of 3 or more atoms; or
(b) the dianhydride comprises: (i) a first dianhydride at 5 to 95% (mol %) and (ii) a second dianhydride at 5 to 95% (mol %), wherein (1) the first dianhydride comprises a first dianhydride linear aliphatic backbone chain comprising carbon atoms and optionally one or more oxygen atoms therein, extending a length of 3 to 30 atoms, and having a ratio of carbon:oxygen of 2:1 to 3:0, and (2) the second dianhydride does not comprise any linear aliphatic backbone chain extending a length of 3 or more atoms.

US Pat. No. 10,428,160

COLORIMETRIC HYDROGEL BASED NANOSENSOR FOR DETECTION OF THERAPEUTIC LEVELS OF IONIZING RADIATION

ARIZONA BOARD OF REGENTS ...

6. An apparatus comprising:a substantially colorless hydrogel to receive a low dose of radiation and form a radiated hydrogel having a color; and
a detector optically coupled to the radiated hydrogel, wherein the radiated hydrogel comprises a plasmonic nanoparticle.

US Pat. No. 10,428,138

ANTIBODY AND ANTIBODY-CONTAINING COMPOSITION

Ostrich Pharma KK, Kyoto...

1. A lotion, comprising:ostrich antibodies which specifically bind to a surface protein of a virus, wherein the virus comprises any one of HPV type 6, 11, 16 or 18; and
water, glycerol, ethanol, sodium polyacrylate, hydroxyethyl cellulose, phenoxyethanol, EDTA-2Na, paraben, polysorbate 80, and fatty acid sorbitan.

US Pat. No. 10,428,122

TUBERCULOSIS COMPOSITIONS AND METHODS OF TREATING OR PREVENTING TUBERCULOSIS

International AIDS Vaccin...

1. A fusion protein comprising at least four or five Mycobacterium tuberculosis (Mtb) antigens, wherein the Mtb antigens are chosen from Rv1009, Rv3136, Rv3615c, Rv2628, Rv2034, and Rv3136 N-terminus, and wherein the fusion protein is chosen from:Rv1009-Rv2628-Rv3615c-Rv3136;
Rv1009-Rv2034-Rv2628-Rv3615c-Rv3136;
Rv1009-Rv3615c-Rv2034-Rv2628;
Rv3615c-Rv2034-Rv2628-Rv1009;
Rv2034-Rv3615c-Rv2628-Rv3136;
Rv3136-Rv2628-Rv3615c-Rv2034;
Rv1009-Rv3136Nt-Rv2628-Rv2034-Rv3615c;
Rv2034-Rv3615c-Rv3136Nt-Rv2628-Rv1009;
Rv3615c-Rv2628-Rv1009-Rv3136Nt-Rv2034;
Rv1009-Rv2628-Rv3136Nt-Rv2034-Rv3615c;
Rv2628-Rv3136Nt-Rv1009-Rv2034-Rv3615c; and
Rv2628-Rv3136Nt-Rv2034-Rv3615c-Rv1009.

US Pat. No. 10,428,112

MULTIPLEXED SAME TYPE-ANTIGENIC PEPTIDE

RIKEN, Wako-shi, Saitama...

1. A multiplexed same type-antigenic peptide comprising a dendritic core and B-cell recognition peptides, wherein the multiplexed same type-antigenic peptide comprises 4 to 8 B-cell recognition peptides of the same type, which are bound to the terminal ends of the dendritic core directly or via a spacer, and production of a class-switched antibody is induced by directly stimulating B cells in vivo in the absence of a T cell epitope; wherein the dendritic core has the following structure:

US Pat. No. 10,428,109

PROCESS FOR THE PREPARATION OF 1,5-BENZOTHIAZEPINE COMPOUNDS

1. A process for the preparation of a compound of formula (I):
comprising reacting a compound of formula (II):

with a compound of formula (III):

wherein
R6 is a suitable protecting group;
to obtain a compound of formula (IV):

and deprotecting said compound of formula (IV) to obtain the compound of formula (I).

US Pat. No. 10,428,108

DIFLUOROKETAMIDE DERIVATIVES

Hoffmann-La Roche Inc., ...

1. A compound of formula (I)
wherein:
R1 is alkyl, optionally substituted cycloalkyl, haloalkyl, optionally substituted heterocycloalkylalkyl optionally substituted arylalkyl or optionally substituted heteroarylalkyl, wherein each moiety is optionally substituted by one to three substituents independently selected from halogen, alkyl, haloalkyl, cycloalkyl, cyano, hydroxyl, alkoxy, haloalkoxy or phenyl;
R2, R3 R4, R6, R7 and R9 are independently selected from hydrogen, alkyl or cycloalkyl;
R5 is optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl or optionally substituted heteroarylalkyl, wherein each moiety is optionally substituted by one to three substituents independently selected from halogen, alkyl, haloalkyl, cycloalkyl, cyano, hydroxyl, alkoxy, haloalkoxy or phenyl;
R8 is optionally substituted adamantylalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted dicycloalkylalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted arylalkenyl, optionally substituted diarylalkyl, optionally substituted aryloxyalkyl, optionally substituted diaryloxyalkyl, optionally substituted arylaryloxyalkyl, optionally substituted heteroarylaryloxyalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, optionally substituted heteroarylalkenyl, optionally substituted arylheteroarylalkyl, optionally substituted arylheteroaryloxyalkyl or optionally substituted aryloxyheteroarylalkyl, wherein each moiety is optionally substituted by one to three substituents independently from selected halogen, alkyl, haloalkyl, cycloalkyl, cyano, hydroxyl, alkoxy, haloalkoxy or phenyl;
wherein a heterocycloalkyl moiety is a ring system of 4 to 9 ring atoms, comprising 1, 2, or 3 ring heteroatoms selected from N, O and S, the remaining ring atoms being carbon, heteroaryl moiety is a ring system of 5 or ring atoms, comprising 1, 2, 3 or 4 heteroatoms selected from N, O and S; the remaining ring atoms being carbon and an aryl moiety is a monovalent aromatic carbocyclic mono- or bicyclic ring system comprising 6 to 10 carbon ring atoms;
or, a pharmaceutically acceptable salt thereof.

US Pat. No. 10,428,106

PHOSPHATE REPLACEMENT MRNA CAP ANALOGS

ModernaTX, Inc., Cambrid...

1. An RNA molecule having a 5? end comprising a compound of formula (III):
wherein
indicates the attachment point of the 5? end to the RNA molecule;B1 is
whereinindicates the attachment point of B1 to the compound;Ra, Rb, and Rc are H;
R1 is CH3;
B2 is
whereinindicates the attachment point of B2 to the compound;Rd, Re, and Rf are H;
X1 is N or N+(CH3);
X2 is O;
R20, R21, R22, and R23 are H;
R27 and R28 are OH;
R2 is OR3;
R3 is H or CH3; and
Y2 is
whereinindicates the attachment points of Y2 to the compound.

US Pat. No. 10,428,105

ALKYNYL NUCLEOSIDE ANALOGS AS INHIBITORS OF HUMAN RHINOVIRUS

Novartis AG, Basel (CH)

1. The compound:
or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,428,103

LABELLED NUCLEOTIDES

Illumina Cambridge Limite...

1. A nucleoside or nucleotide comprising a base attached to a detectable label via a phosphine-cleavable linker comprising a disulfide, wherein the nucleoside or nucleotide comprises a ribose or deoxyribose moiety with a hydroxyl protecting group attached to the 2? or 3? oxygen atom, and wherein the protecting group is azidomethyl.

US Pat. No. 10,428,102

GLYCOLIPIDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THERAPY

THE UNIVERSITY OF NOTTING...

1. A compound of Formula Ie:or a pharmaceutically acceptable salt thereof, for use in medicine,wherein:
R1 a carbohydrate group;
R2 is selected from hydrogen, a C1-C24 alkyl or a C1-C24 derivative of an alkyl group, a C2-C24 alkenyl or a C2-C24 derivative of an alkenyl group, and a C2-C24 alkynyl group or a C2-C24 derivative of an alkynyl group;
R3 is selected from hydrogen, a C1-C24 alkyl or a C1-C24 derivative of an alkyl group, a C2-C24 alkenyl or a C2-C24 derivative of an alkenyl group, and a C2-C24 alkynyl group or a C2-C24 derivative of an alkynyl group;
X is either absent or is -O-, -NRa-, -S- or -CRaRb-, wherein Ra and Rb are independently selected from the group consisting of hydrogen and C1-C4 alkyl; and
n is an integer from 1 to 6;
wherein said derivative of alkyl, alkenyl or alkynyl group is composed of said alkyl, alkenyl or alkynyl group wherein one or more of the hydrogen atoms in the hydrocarbon chain of said derivative are replaced with substituent groups selected from hydroxyl, amino, carboxyl, aryl, or heteroaryl groups

US Pat. No. 10,428,099

PHARMACEUTICAL CO-CRYSTAL COMPOSITION AND USE THEREOF

SYN-NAT PRODUCTS ENTERPRI...

1. A co-crystal comprising a platinum analogue and a diacid,wherein the platinum analogue is selected from the group consisting of:
andthe diacid is selected from the group consisting of:

provided that when the platinum analogue is carboplatin (Pt-01), the diacid is not CF-01, CF-04, CF-10A, CF-10B, CF-10C, or CF-10D.

US Pat. No. 10,428,095

COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS

Achillion Pharmaceuticals...

1. A compound of structureor a pharmaceutically acceptable salt thereof.

US Pat. No. 10,428,087

PYRIMIDINONES AS PI3K INHIBITORS

Incyte Corporation, Wilm...

1. A compound of Formula If:or pharmaceutically acceptable salt thereof, wherein:A is aryl, heteroaryl, cycloalkyl, or heterocycloalkyl, each optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from halo, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, halosulfanyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, CN, NO2, ORa, SRa, C(O)Rb, C(O)NRcRd, C(O)ORa, OC(O)Rb, OC(O)NRcRd, NRcRd, NRcC(O)Rb, NRcC(O)ORa, NRcC(O)NRcRd, C(?NRe)Rb, C(?NRe)NRcRd, NRcC(?NRe)NRcRd, NRcS(O)Rb, NRcS(O)2Rb, NRcS(O)2NRcRd, S(O)Rb, S(O)NRcRd, S(O)2Rb, and S(O)2NRcRd; wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, or heterocycloalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from halo, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, halosulfanyl, CN, NO2, ORa, SRa, C(O)Rb, C(O)NRcRd, C(O)ORa, OC(O)Rb, OC(O)NRcRd, C(?NRe)NRcRd, NRcC(?NRe)NRcRd, NRcRd, NRcC(O)Rb, NRcC(O)ORa, NRcC(O)NRcRd, NRcS(O)Rb, NRcS(O)2Rb, NRcS(O)2NRcRd, S(O)Rb, S(O)NRcRd, S(O)2Rb, and S(O)2NRcRd;
R1 is ORA, SRA, S(O)RA, S(O)2RA, NRARB, NRcC(O)NRARB, NRCC(O)ORA, NRCC(?NRE)NRARB, NRCS(O)2RA, NRCS(O)2NRCRA, heterocycloalkyl, or heteroaryl, wherein said heterocycloalkyl or heteroaryl is optionally substituted with 1, 2, or 3 substituents independently selected from —(C1-4 alkyl)r-Cy1, halo, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, halosulfanyl, CN, NO2, ORa1, SRa1, C(O)Rb1, C(O)NRc1Rd1, C(O)ORa1, OC(O)Rb1, OC(O)NRc1Rd1, C(?NRe)NRc1Rd1, NRc1C(?NRe)NRc1Rd1, NRc1Rd1, NRc1C(O)Rb1, NRc1C(O)ORa1, NRc1C(O)NRc1Rd1, NRc1S(O)Rb1, NRc1S(O)2Rb1, NRc1S(O)2NRc1Rd1, S(O)Rb1, S(O)NRc1Rd1, S(O)2Rb1, and S(O)2NRc1Rd1;
R2a is H, halo, OH, CN, C1-6 alkyl, C1-6 haloalkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl, wherein said C1-6 alkyl, C1-6 haloalkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, or 3 substituents independently selected from halo, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, halosulfanyl, CN, NO2, ORa2, SRa2, C(O)Rb2, C(O)NRc2Rd2, C(O)ORa2, OC(O)Rb2, OC(O)NRc2Rd2, C(?NRe)NRc2Rd2, NRc2C(?NRe)NRc2Rd2, NRc2Rd2, NRc2C(O)Rb2, NRc2C(O)ORa2, NRc2C(O)NRc2Rd2, NRc2S(O)Rb2, NRc2S(O)2Rb2, NRc2S(O)2NRc2Rd2, S(O)Rb2, S(O)NRc2Rd2, S(O)2Rb2, and S(O)2NRc2Rd2;
R3, R4, R5, and R6 are independently selected from H, halo, CN, NO2, ORa3, SRa3, C(O)Rb3, C(O)NRc3Rd3, C(O)ORa3, NRc3Rd3, NRc3C(O)Rb3, NRc3S(O)2Rb3, NRc3S(O)2NRc3Rd3, S(O)2NRc3Rd3, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa3, SRa3, C(O)Rb3, C(O)NRc3Rd3, C(O)ORa3, OC(O)Rb3, OC(O)NRc3Rd3, NRc3Rd3, NRc3C(O)Rb3, NRc3C(O)NRc3Rd3, NRc3C(O)ORa3, C(?NRe)NRc3Rd3, NRc3C(?NRe)NRc3Rd3, S(O)Rb3, S(O)NRc3Rd3, S(O)2Rb3, NRc3S(O)2Rb3, NRc3S(O)2NRc3Rd3, and S(O)2NRc3Rd3;
RA is heteroaryl, heterocycloalkyl, heteroarylalkyl, or heterocycloalkylalkyl, each optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from —(C1-4 alkyl)r-Cy1, halo, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, halosulfanyl, CN, NO2, ORa1, SRa1, C(O)Rb1, C(O)NRc1Rd1, C(O)ORa1, OC(O)Rb1, OC(O)NRc1Rd1, C(?NRe)NRc1Rd1, NRc1C(?NRe)NRc1Rd1, NRc1Rd1, NRc1C(O)Rb1, NRc1C(O)ORa1, NRc1C(O)NRc1Rd1, NRc1S(O)Rb1, NRc1S(O)2Rb1, NRc1S(O)2NRc1Rd1, S(O)Rb1, S(O)NRc1Rd1, S(O)2Rb1, and S(O)2NRc1Rd1;
RB and RC are independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
RE is H, CN, NO2, ORa5, SRb5, S(O)2Rb5, C(O)Rb5, S(O)2NRc5Rd5, or C(O)NRc5Rd5;
Cy1 is aryl, heteroaryl, cycloalkyl, or heterocycloalkyl, each optionally substituted by 1, 2, 3, 4, or 5 substituents independently selected from halo, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, halosulfanyl, CN, NO2, ORa1, SRa1, C(O)Rb1, C(O)NRc1Rd1, C(O)ORa1, OC(O)Rb1, OC(O)NRc1Rd1, C(?NRe)NRc1Rd1, NRc1C(?NRe)NRc1Rd1, NRc1Rd1, NRc1C(O)Rb1, NRc1C(O)ORa1, NRc1C(O)NRc1Rd1, NRc1S(O)Rb1, NRc1S(O)2Rb1, NRc1S(O)2NRc1Rd1, S(O)Rb1, S(O)NRc1Rd1, S(O)2Rb1, and S(O)2NRc1Rd1;
Ra, Rb, Rc, and Rd are independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
or Rc and Rd together with the N atom to which they are attached form a 3-, 4-, 5-, 6-, or 7-membered heterocycloalkyl group or a heteroaryl group, each optionally substituted with 1, 2, or 3 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
Ra1, Rb1, Rc1, and Rd1 are independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
or Rc1 and Rd1 together with the N atom to which they are attached form a 3-, 4-, 5-, 6-, or 7-membered heterocycloalkyl group or a heteroaryl group, each optionally substituted with 1, 2, or 3 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
Ra2, Rb2, Rc2, and Rd2 are independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
or Rc2 and Rd2 together with the N atom to which they are attached form a 3-, 4-, 5-, 6-, or 7-membered heterocycloalkyl group or a heteroaryl group, each optionally substituted with 1, 2, or 3 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
Ra3, Rb3, Rc3, and Rd3 are independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from C1-6 alkyl, C1-6 haloalkyl, halo, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRc5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
or Rc3 and Rd3 together with the N atom to which they are attached form a 3-, 4-, 5-, 6-, or 7-membered heterocycloalkyl group or a heteroaryl group, each optionally substituted with 1, 2, or 3 substituents independently selected from C1-6 alkyl, halo, C1-6 haloalkyl, CN, ORa5, SRa5, C(O)Rb5, C(O)NRc5Rd5, C(O)ORa5, OC(O)Rb5, OC(O)NRc5Rd5, NRc5Rd5, NRa5C(O)Rb5, NRc5C(O)NRc5Rd5, NRc5C(O)ORa5, C(?NRf)NRc5Rd5, NRc5C(?NRf)NRc5Rd5, S(O)Rb5, S(O)NRc5Rd5, S(O)2Rb5, NRc5S(O)2Rb5, NRc5S(O)2NRc5Rd5, and S(O)2NRc5Rd5;
Re and Rf are independently selected from H, CN, NO2, ORa5, SRb5, S(O)2Rb5, C(O)Rb5, S(O)2NRc5Rd5, and C(O)NRc5Rd5;
Ra5, Rb5, Rc5, and Rd5 are independently selected from H, C1-6 alkyl, C1-6 haloalkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, and heterocycloalkylalkyl, wherein said C1-6 alkyl, C1-6 haloalkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, or heterocycloalkylalkyl is optionally substituted with 1, 2, or 3 substituents independently selected from OH, CN, amino, halo, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, C1-6 alkylamino, di(C1-6 alkyl)amino, C1-6 haloalkyl, and C1-6 haloalkoxy;
or Rc5 and Rd5 together with the N atom to which they are attached form a 3-, 4-, 5-, 6-, or 7-membered heterocycloalkyl group or heteroaryl group, each optionally substituted with 1, 2, or 3 substituents independently selected from OH, CN, amino, halo, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, C1-6 alkylamino, di(C1-6 alkyl)amino, C1-6 haloalkyl, and C1-6 haloalkoxy; and
r is 0 or 1;
provided that:
a) when A is 3-fluorophenyl; R2a is H; R3 is methyl; and R4, R5, and R6 are H; then, R1 is other than 4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl; and
b) when A is 1,3-dioxolan-2-yl; R2a, R3, R4, and R6 are H; then, R1 is other than 1-(tert-butoxycarbonyl)piperidin-4-yl.

US Pat. No. 10,428,083

HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR

BAYER PHARMA AKTIENGESELL...

1. Compound of the formula (I)
in which
the ring A is an azaheterocycle of the formula

in which * marks the bond to the adjoining CH(R1) group,
R5 is hydrogen, (C1-C4)-alkyl, hydroxyl, (C1-C4)-alkoxy, amino, (C1-C5)-alkanoylamino or (C1-C4)-alkoxycarbonylamino,
R6 is hydrogen, methyl or ethyl,
R7A and R7B are the same or different and are independently hydrogen or (C1-C4)-alkyl,
R8 is hydrogen, (C1-C4)-alkyl, (C2-C4)-alkenyl, (C1-C5)-alkanoyl or (C1-C4)-alkoxycarbonyl,
where (C1-C4)-alkyl may be up to disubstituted by hydroxyl,
R9A and R9B are the same or different and are independently hydrogen or (C1-C4)-alkyl
and
X is O, N(R10) or S, in which
R10 is hydrogen, cyano or (C1-C4)-alkoxycarbonyl,
R1 is hydrogen or methyl,
R2 is hydrogen, methyl or ethyl, where methyl and ethyl may be up to trisubstituted by fluorine,
R3 is (C2-C6)-alkyl, (C2-C6)-alkenyl or (C2-C6)-alkynyl,
where (C2-C6)-alkyl may be substituted by a radical selected from the group of hydroxyl, methoxy, ethoxy, trifluoromethoxy, cyclopropyl, cyclobutyl, oxetanyl and phenyl, and up to trisubstituted by fluorine,
and
(C2-C6)-alkenyl may be up to trisubstituted by fluorine,
where the cyclopropyl and cyclobutyl groups mentioned may in turn be up to disubstituted, identically or differently, by a radical selected from fluorine and methyl,
or
R3 is a group of the formula —CH2—R14 in which
R14 is cyclopropyl, cyclobutyl, oxetanyl or tetrahydrofuranyl, where cyclopropyl, cyclobutyl and oxetanyl may be up to disubstituted, identically or differently, by a radical selected from fluorine and methyl,
and
R4 is (C1-C6)-alkyl or (C2-C6)-alkenyl,
where (C1-C6)-alkyl may be up to pentasubstituted and (C2-C6)-alkenyl up to trisubstituted by fluorine
and
where one CH2 group in (C1-C6)-alkyl may be exchanged for —O—, —S— or —S(O)2—, with the proviso that there are at least two carbon atoms between such a heteroatom and the uracil N1 atom,
or
R4 is a group of the formula —(CH2)m—CN, —(CH2)n—R11 or —(CH2)p—R12, in which
m is the number 1, 2, 3 or 4,
n is the number 2 or 3,
p is the number 1 or 2,
R11 is dimethylamino, diethylamino or azetidino
and
R12 is (C3-C6)-cycloalkyl, oxetanyl, tetrahydrofuranyl, tetrahydropyranyl or 5-membered azaheteroaryl,
where (C3-C6)-cycloalkyl may be up to disubstituted, identically or differently, by a radical selected from fluorine and methyl
and
azaheteroaryl may be up to disubstituted, identically or differently, by a radical selected from methyl and trifluoromethyl,
or
R4 is a group of the formula —(CH2)2—O—R13 in which
R13 is (C3-C6)-cycloalkyl,
and a salt, a solvate, and a solvate of the salt thereof.

US Pat. No. 10,428,082

TRIAZOLE DERIVATIVES OF MELAMPOMAGNOLIDE B AND METHODS OF USE THEREOF

BioVentures, LLC, Little...

1. A compound of Formula (II):
wherein:
R1, R2, R3, R4, and R5 are each independently selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl, substituted arylalkyl, arylalkenyl, substituted arylalkenyl, arylalkynyl, substituted arylalkynyl, heteroaryl, substituted heteroaryl, methyl, trifluoromethyl, halogen, cyano, nitro, amidine, amino, carboxyl, ester, alkylalkylamino, dialkylamino, hydroxyl, alkoxy or arylalkoxy (e.g. methoxy, ethoxy, benzyloxy, substituted benzyloxy) and combinations thereof; and R1 and R2 or R2 and R3 or R3 and R4 or R4 and R5 together can optionally form an optionally substituted cycloalkyl, aryl or heteroaryl 5 or 6 membered ring.

US Pat. No. 10,428,057

BICYCLO[1.1.1]PENTANE INHIBITORS OF DUAL LEUCINE ZIPPER (DLK) KINASE FOR THE TREATMENT OF DISEASE

Board of Regents, The Uni...

1. A method of treating a disease selected from the group consisting ofchemotherapy-induced cognitive deficits (CICD),
chemotherapy-induced cognitive impairment (CICI),
chemotherapy-induced peripheral neuropathy (CIPN),
diabetic neuropathy,
Alzheimer's disease,
amyotrophic lateral sclerosis,
frontotemporal dementia,
Huntington's disease,
Kennedy's disease,
Lewy body disease,
Parkinson's disease,
progressive supranuclear palsy,
spinocerebellar ataxia,
traumatic brain injury (TBI), and
traumatic injury to the central nervous system or peripheral nervous system neurons,
the method comprising administering to a patient in need thereof a therapeutically effective amount of a compound of Formula I:

or a pharmaceutically acceptable salt thereof,
wherein:
X1 is selected from C or N;
X2 is selected from C or N;
exactly one of X1 and X2 is N;
X3 is N;
X4 and X5 are C;
X1, X2, X3, X4, and X5 form a five membered heteroaryl;
R1 is selected from alkyl, cycloalkyl, or heterocycloalkyl, any of which is optionally substituted with one to three R5 groups;
R2 is H or is selected from alkyl, amino, aryl, cycloalkyl, haloalkyl, heteroalkyl, heteroaryl, heterocycloalkyl, or sulfonylalkyl, any of which is optionally substituted with one to three R6 groups;
R3 is selected from H, alkyl, (alkoxy)alkyl, (arylalkoxy)alkyl, (heteroarylalkoxy)alkyl, cyano, cycloalkyl, halo, haloalkoxy, or haloalkyl;
R4 is (NR4a)2, wherein each R4a is independently selected from hydrogen, C1-4alkyl, or C1-4haloalkyl;
or R3 and R4 together with the atoms to which they are attached form a 5- or 6-membered heteroaryl or heteroalkyl ring, optionally substituted with one to three R7 groups;
each R5 and R6 is independently selected from C1-4alkyl, C1-4haloalkyl, C1-4alkoxy, C1-4haloalkoxy, C1-4-alkylthio, C1-4haloalkylthio, aryl, heteroaryl, C3-7cycloalkyl, C3-7heterocycloalkyl, (aryl)C1-4alkyl, (heteroaryl)C1-4alkyl, (C3-7cycloalkyl)C1-4alkyl, (C3-7heterocycloalkyl)C1-4alkyl, (ethenyl)C1-4alkyl, (ethynyl)C1-4alkyl, (aryl)C1-4alkoxy, (heteroaryl)C1-4alkoxy, (C3-7cycloalkyl)C1-4alkoxy, (C3-7heterocycloalkyl)C1-4alkoxy, (aryl)C1-4alkylthio, (heteroaryl)C1-4alkylthio, (C3-7cycloalkyl)C1-4alkylthio, (C3-7heterocycloalkyl)C1-4alkylthio, amino, halo, hydroxy, cyano, or oxo; and
each R7 is independently selected from C1-4alkyl, C1-4haloalkyl, C1-4alkoxy, C1-4haloalkoxy, aryl, heteroaryl, C3-7cycloalkyl, C3-7heterocycloalkyl, (aryl)C1-4alkyl, (heteroaryl)C1-4alkyl, (C3-7cycloalkyl)C1-4alkyl, (C3-7heterocycloalkyl)C1-4alkyl, halo, hydroxy, cyano, or oxo.

US Pat. No. 10,428,050

SUBSTITUTED REVERSE PYRIMIDINE BMI-1 INHIBITORS

PTC THERAPEUTICS, INC., ...

1. A compound of Formula (I):
or a form thereof, wherein
R1 is bicyclic heteroaryl or bicyclic heterocyclyl substituted on a carbon atom ring member with one, two, three or four R5 substituents, or on a nitrogen atom ring member with an oxygen atom substituent to form an N-oxide;
X is N or N substituted with an oxygen atom substituent to form an N-oxide;
R2 is amino;
R3 is hydrogen, cyano, halo, C1-8alkyl, amino, C1-8alkyl-amino or (C1-8alkyl)2-amino;
R4 is phenyl, optionally substituted with one, two, three or four R6 substituents;
R5 is independently selected from the group consisting of cyano, halo, hydroxyl, nitro, oxo, C1-8alkyl, cyano-C1-8alkyl, halo-C1-8alkyl, hydroxyl-C1-8alkyl, C1-8alkoxy, C1-8alkoxy-C1-8alkyl, halo-C1-8alkoxy, C2-8alkenyl, C1-8alkoxy-C2-8alkenyl, C2-8alkynyl, C1-8alkoxy-C2-8alkynyl, carboxyl, amino, C1-8alkyl-amino, (C1-8alkyl)2-amino, amino-C1-8alkyl, C1-8alkyl-amino-C1-8alkyl, (C1-8alkyl)2-amino-C1-8alkyl, hydroxyl-C1-8alkyl-amino, hydroxyl-C1-8alkyl-amino-C1-8alkyl, hydroxyl-C1-8alkyl-amino-C1-8alkyl-amino, C1-8alkyl-thio, C1-8alkyl-carbonyl, C1-8alkyl-carbonyl-amino, C1-8alkyl-carbonyl-oxy, C1-8alkyl-carbonyl-oxy-C1-8alkyl, C1-8alkoxy-carbonyl, C1-8alkoxy-carbonyl-C1-8alkyl, C1-8alkoxy-carbonyl-amino, C1-8alkyl-sulfonyl, C3-14cycloalkyl, aryl, aryl-C1-8alkyl, aryl-amino, aryl-C1-8alkyl-amino, heteroaryl, heteroaryl-C1-8alkyl and heterocyclyl, wherein C3-14cycloalkyl, aryl, heteroaryl or heterocyclyl and the aryl and heteroaryl portions of aryl-C1-8alkyl, aryl-amino, aryl-C1-8alky-amino and heteroaryl-C1-8alkyl are each optionally substituted with one, two, three or four halo, C1-8alkyl, halo-C1-8alkyl, hydroxyl-C1-8alkyl, C1-8alkoxy, halo-C1-8alkoxy, hydroxyl-C1-8alkoxy or carboxyl substituents;
R6 is independently selected from the group consisting of cyano, halo, nitro, C1-8alkyl, halo-C1-8alkyl, hydroxyl-C1-8alkyl, C1-8alkoxy, halo-C1-8alkoxy, C2-8alkenyl, C1-8alkoxy-C2-8alkenyl, C2-8alkynyl, C1-8alkoxy-C2-8alkynyl, carboxyl, formyl, formyl-oxy, C1-8alkyl-carbonyl, halo-C1-8alkyl-carbonyl, C1-8alkyl-thio, halo-C1-8alkyl-thio, amino, C1-8alkyl-amino, (C1-8alkyl)2-amino, C1-8alkyl-carbonyl, C1-8alkyl-carbonyl-oxy, C1-8alkyl-carbonyl-oxy-C1-8alkyl, C1-8alkoxy-carbonyl, halo-C1-8alkoxy-carbonyl, C1-8alkoxy-carbonyl-C1-8alkyl, C1-8alkoxy-carbonyl-amino, C1-8alkoxy-carbonyl-amino-C1-8alkyl, amino-carbonyl, C1-8alkyl-amino-carbonyl, (C1-8alkyl)2-amino-carbonyl, C1-8alkyl-carbonyl-amino, C1-8alkyl-carbonyl-amino-C1-8alkyl, amino-C1-8alkyl, C1-8alkyl-amino-C1-8alkyl, (C1-8alkyl)2-amino-C1-8alkyl, amino-C1-8alkyl-amino, C1-8alkyl-amino-C1-8alkyl-amino, (C1-8alkyl)2-amino-C1-8alkyl-amino, hydroxyl-C1-8alkyl-amino, hydroxyl-C1-8alkyl-amino-C1-8alkyl, hydroxyl-C1-8alkyl-amino-C1-8alkyl-amino, imino-C1-8alkyl, hydroxyl-imino-C1-8alkyl, C1-8alkoxy-imino-C1-8alkyl, C1-8alkyl-sulfonyl, halo-C1-8alkyl-sulfonyl, amino-sulfonyl, C1-8alkyl-amino-sulfonyl, (C1-8alkyl)2-amino-sulfonyl, B(OR8)2, C3-14cycloalkyl, heterocyclyl, aryl and heteroaryl, wherein C3-14cycloalkyl, heterocyclyl, aryl, and heteroaryl are each optionally substituted with one, two, three or four halo or C1-8alkyl substituents;
R8 is independently hydrogen or C1-8alkyl;
wherein the form of the compound is selected from the group consisting of a free acid, free base, salt, ester, hydrate, solvate, chelate, clathrate, isotopologue, stereoisomer, racemate, enantiomer, diastereomer and tautomer thereof.

US Pat. No. 10,428,048

ANDROGEN RECEPTOR ANTAGONISTS

City of Hope, Duarte, CA...

1. A compound, or a pharmaceutically acceptable salt thereof, having the formula:
wherein
R1 is hydrogen or substituted or unsubstituted pyrid-2-yl;
R2 is independently a hydrogen, halogen, —CX23, —CHX22, —CH2X2, —CN, —SOn2R10, —SOv2NR7R8, —NHNR7R8, —ONR7R8, —NHC?(O)NHNR7R8, —NHC?(O)NR7R8, —N(O)m2, —NR7R8, —C(O)R9, —C(O)—OR9, —C(O)NR7R8, —OR10, —NR7SO2R10, —NR7C?(O)R9, —NR7C(O)—OR9, —NR7OR9, —OCX23, —OCHX22, —OCH2X2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
R3 is independently a hydrogen, halogen, —CX33, —CHX32, —CH2X3, —CN, —SOn3R14, —SOv3NR11R12, —NHNH2, —ONR11R12, —NHC?(O)NHNH2, —NHC?(O)NR11R12, —N(O)m3, —NR11R12, —C(O)R13, —C(O)—OR13, —C(O)NR11R12, —OR14, —NR11SO2R14, —NR11C?(O)R13, —NR11C(O)—OR13, —NR11OR13, —OCX33, —OCHX32, —OCH2X3, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
R7, R8, R9, R10, R11, R12, R13 and R14 are independently hydrogen, halogen, —CX3, —CHX2, —CH2X, —OCX3, —OCHX2, —OCH2X, —CN, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO3H, —SO4H, —SO2NH2, —NHNH2, —ONH2, —NHC?(O)NHNH2, —NHC?(O)NH2, —NHSO2H, —NHC?(O)H, —NHC(O)—OH, —NHOH, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and R8 substituents bonded to the same nitrogen atom may optionally be joined to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl; R11 and R12 substituents bonded to the same nitrogen atom may optionally be joined to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl;
R4 is independently hydrogen, a —CX43, —CHX42, —CH2X4, —CN, —C(O)H, —C(O)OH, —C(O)NH2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
R5 is independently a hydrogen, halogen, —CX53, —CHX52, —CH2X5, —CN, —C(O)H, —C(O)OH, —C(O)NH2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
R6 is independently a hydrogen, halogen, —CX63, —CHX62, —CH2X6—CN, —C(O)H, —C(O)OH, —C(O)NH2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
L1 is independently a bond, substituted or unsubstituted alkylene, substituted or unsubstituted alkenylene, substituted or unsubstituted alkynylene, substituted or unsubstituted heteroalkylene, substituted or unsubstituted heteroalkenylene, or substituted or unsubstituted heteroalkynylene;
m2, m3, v2, and v3 are independently 1 or 2;
n2 and n3 are independently an integer from 0 to 4;
X1, X2, X3, X4, X5, and X6 are independently —Cl, —Br, —I, or —F.

US Pat. No. 10,428,047

MAP KINASE MODULATORS AND USES THEREOF

The Trustees of Columbia ...

1. A method of treating a tauopathy in a subject comprising administration of a therapeutically effective amount of a compound of formula (I), or a composition comprising a compound of formula (I),whereinX1 is N and X2 is CH, or X1 is CH and X2 is N;
R1 is —N(R4)2, cyclopropyl, or R5-piperidin-4-yl;
R2 is independently D or halogen;
R3 is naphthyl, quinolinyl, or isoquinolinyl, wherein said naphthyl, quinolinyl, or isoquinolinyl is optionally independently substituted with at least one D, halogen, (C1-C3)-alkoxy, or (C1-C3)-alkoxy substituted with at least one D;
R4 is independently H, (C1-C4)-alkyl, (C1-C4)-alkyl substituted with at least one D, (C3-C5)-cycloalkyl, or each R4 together with the nitrogen to which they are attached form a 3-7 membered heterocyclic ring, wherein one of the carbon atoms is optionally replaced with NR6, O or S, and wherein the 3-7 membered heterocyclic ring is optionally substituted with a (C1-C3)-alkyl;
R5 is H or (C1-C3)-alkyl, or (C1-C3)-alkyl substituted with at least one D;
R6 is H, (C1-C3)-alkyl, (C1-C3)-alkyl substituted with at least one D, or pyrimidin-2-yl; and
n is an integer from 0-4; or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,428,046

N-SUBSTITUTED SULFONAMIDE COMPOUND AND METHOD FOR PRODUCING SAME

UBE INDUSTRIES, LTD., Ub...

15. A compound of the general formula (9):
wherein R5 is an alkyl group, and X2 is a halogen atom or a hydroxyl group.

US Pat. No. 10,428,045

BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF

Silverback Therapeutics, ...

1. A conjugate represented by the formula:wherein Antibody is an antibody construct, L3 is a linker moiety, and D is a compound represented by the structure of Formula (IIB):or a pharmaceutically acceptable salt thereof, wherein:L10 is selected from —C(O)—, and —C(O)N(R10)—*, wherein * represents where L10 is bound to R5—;
L2 is selected from —C(O)— and —C(O)N(R10)—;
R1 and R2 are independently selected from hydrogen; and C1-10 alkyl, C2-10 alkenyl, and C2-10 alkynyl, each of which is optionally substituted with one or more substituents independently selected from halogen, —OR10, —SR10, —C(O)N(R10)2, —N(R10)2, —S(O)R10, —S(O)2R10, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), and —CN;
R4 is selected from:
OR10, —N(R10)2, —C(O)N(R10)2, —C(O)R10, —C(O)OR10, —S(O)R10, and —S(O)2R10; and
C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, each of which is optionally substituted with one or more substituents independently selected from halogen, —OR10, —SR10, —C(O)N(R10)2, —N(R10)C(O)R10, —N(R10)C(O)N(R10)2, —N(R10)2, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), —CN, C3-12 carbocycle, and 3- to 12-membered heterocycle; and
C3-12 carbocycle, and 3- to 12-membered heterocycle, each of which is optionally substituted with one or more substituents independently selected from halogen, —OR10, —SR10, —C(O)N(R10)2, —N(R10)C(O)R10, —N(R10)C(O)N(R10)2, —N(R10)2, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), —CN, C1-6 alkyl, C2-6 alkenyl, and C2-6 alkynyl;
R5 is selected from unsaturated C4-8 carbocycle; bicyclic carbocycle; and fused 5-5, fused 5-6, and fused 6-6 bicyclic heterocycle, wherein R5 is optionally substituted and wherein substituents are independently selected at each occurrence from:
halogen, —OR10, —SR10, —C(O)N(R10)2, —N(R10)C(O)R10, —N(R10)C(O)N(R10)2, —N(R10)2, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), and —CN; and
C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, each of which is optionally substituted with one or more substituents independently selected from halogen, —OR10, —SR10, —C(O)N(R10)2, —N(R10)C(O)R10, —N(R10)C(O)N(R10)2, —N(R10)2, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), —CN, C3-12 carbocycle, and 3- to 12-membered heterocycle; and
C3-12 carbocycle, and 3- to 12-membered heterocycle, each of which is optionally substituted with one or more substituents independently selected from halogen, —OR10, —SR10, —C(O)N(R10)2, —N(R10)C(O)R10, —N(R10)C(O)N(R10)2, —N(R10)2, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), —CN, C1-6 alkyl, C2-6 alkenyl, and C2-6 alkynyl;
R10 is independently selected at each occurrence from:
hydrogen, —NH2, and—C(O)OCH2C6H5; and
C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-12 carbocycle, and 3- to 12-membered heterocycle, each of which is optionally substituted with one or more substituents independently selected from halogen, —OH, —CN, —NO2, —NH2, ?O, ?S, —C(O)OCH2C6H5, —NHC(O)OCH2C6H5, C1-10 alkyl, —C1-10 haloalkyl, —O—C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-12 carbocycle, and 3- to 12-membered heterocycle;
R20, R21, R22, and R23 are independently selected from hydrogen, halogen, —OR10, —SR10, —N(R10)2, —S(O)R10, —S(O)2R10, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), —CN, C1-10 alkyl, C2-10 alkenyl, and C2-10 alkynyl; and
R24 and R25 are independently selected from hydrogen, halogen, —OR10, —SR10, —N(R10)2, —S(O)R10, —S(O)2R10, —C(O)R10, —C(O)OR10, —OC(O)R10, —NO2, ?O, ?S, ?N(R10), —CN, C1-10 alkyl, C2-10 alkenyl, and C2-10 alkynyl; or R24 and R25 taken together form an optionally substituted saturated C3-7 carbocycle.

US Pat. No. 10,428,029

ISOXAZOLE CARBOXAMIDE COMPOUNDS

EPIZYME, INC., Cambridge...

1. A compound having Formula I:
or a pharmaceutically acceptable salt or hydrate thereof,
wherein:
R1 is selected from the group consisting of C1-6 alkyl, C1-4 alkenyl, C1-4 haloalkyl, C3-6 cycloalkyl, and hydroxyalkyl;
R2 is selected from the group consisting of hydrogen, halo, and carboxamido;
A is optionally substituted 4- to 14-membered heterocyclenyl;
with the provisos:
a) when R1 is ethyl, n-propyl, isopropyl, isobutyl, or cyclopropyl; and R2 is hydrogen, then A is not optionally substituted, optionally bridged piperidinenyl; and
b) when R1 is C1-6 alkyl or C3-6 cycloalkyl; and R2 is hydrogen, then A is not optionally substituted pyrrolidinenyl;
X is selected from the group consisting of —S(?O)2—, —S(?O)2N(R7)—, —N(R7)S(?O)2—, —S(?O)2C(R8)(H)—, —C(?O)—, —C(?O)N(R7)—, —N(R7)C(?O)—, —C(?O)O—, —OC(?O)—, —C(?O)C(R8)(H)N(R7)—, —N(R7)C(?O)C(R8)(H)—, —C(R8)(H)C(?O)N(R7)—, —C(R8)(H)N(R7)C(?O)—, and —C(?O)C(R8)(H)—; or X is absent;
Z is selected from the group consisting of hydrogen, optionally substituted C1-6 alkyl, fluoroalkyl, hydroxyalkyl, amino, alkylamino, dialkylamino, heterocycloamino, (amino)alkyl, (alkylamino)alkyl, (dialkylamino)alkyl, (cycloalkylamino)alkyl, (heterocyclo)alkyl, (cycloalkyl)alkyl, (amino)(hydroxy)alkyl, (amino)(aryl)alkyl, (amino)(heteroaryl)alkyl (hydroxy)(aryl)alkyl, (aralkylamino)alkyl, (hydroxyalkylamino)alkyl, alkoxyalkyl, optionally substituted C6-14 aryl, optionally substituted 4- to 14-membered heterocyclo, optionally substituted 5- to 14-membered heteroaryl optionally substituted C3-12 cycloalkyl, aralkyl, and (heteroaryl)alkyl;
wherein —X—Z is attached to any available carbon or nitrogen atom of A;
R7 is selected from the group consisting of hydrogen and C1-4 alkyl; and
R8 is selected from the group consisting of hydrogen, C1-4 alkyl, hydroxy, amino, alkylamino, dialkylamino, cycloalkylamino, (amino)alkyl, (alkylamino)alkyl, (dialkylamino)alkyl, and hydroxyalkyl.

US Pat. No. 10,428,028

HDAC INHIBITORS

BIOMARIN PHARMACEUTICAL I...

1. A method of treating a disease or disorder wherein the disease or disorder is a neurological disorder selected from myotonic dystrophy, spinal muscular atrophy, fragile X syndrome, Huntington's disease, spinocerebellar ataxia, Kennedy's disease, amyotrophic lateral sclerosis, Niemann Pick, Pitt Hopkins, spinal and bulbar muscular atrophy, and Alzheimer's disease; an inflammatory disease; a memory impairment condition; or a drug addiction in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound having a structure of formula (I), or a pharmaceutically acceptable salt thereof:
wherein:
R1—X is attached to only one of the ring nitrogen atoms;
X is:
(i) —Y—[C(Ra)2]a-A-[C(Rb)2]b—B—;
(ii) direct bond; or
(iii) C?O, C(Rj)2—C(?O), C(?O)—C(Rj)2, SO2—NRk, NRk—SO2, C(?O)NRk or NRk—C(?O);wherein:Y is bond, CRc?CRd, O, NRe, or S(O)m;
each of A and B is, independently, a bond, O, NRe, or S(O)m;
a is 1, 2, or 3;
b is 0, 1, 2, or 3;
m is 0, 1, or 2;
each occurrence of Ra and Rb is independently selected from H, F, OH, C1-C6 alkyl, C3-C6 cycloalkyl, NH2, OCO—(C1-C6 alkyl), OCO—(C3-C6 cycloalkyl), C1-C6 alkoxy, C1-C6 fluoroalkoxy, and cyano; or
one or more of the following can apply with respect to Ra and Rb:
any two Ra, together with the carbons to which each is attached, together form C3-C6 cycloalkyl or heterocyclyl including 3-6 ring atoms, in which one of the heterocyclyl ring atoms is selected from O, S(O)m and NRg; or
one Re and one Rb, together with the carbons to which each is attached, form C3-C6 cycloalkyl or heterocyclyl including 3-6 ring atoms, in which one of the heterocyclyl ring atoms is selected from O; S(O)m and NRg; or
any two Rb, together with the carbons to which each is attached, form C3-C6 cycloalkyl or heterocyclyl including 3-6 ring atoms, in which one of the ring atoms is selected from O; S(O)m and NRg;
each of Rc and Rd is independently selected from H, F, OH, C1-C6 alkyl, C3-C5 cycloalkyl, NH2, OCO—(C1-C6 alkyl), OCO—(C3-C5 cycloalkyl), C1-C6 alkoxy, C1-C6 fluoroalkoxy, and cyano;
or Rc and Rd, together with the carbons to which each is attached form a C5-C7 cycloalkyl or heterocyclyl including 3-6 ring atoms, in which from 1-2 of the heterocyclyl ring atoms are independently selected from O, S(O)m and NRg?;
each occurrence of Re, Rf, Rg and Rg? is independently selected from H, C1-C6 alkyl, —C(?O)H, —C(?O)Rh, C(?O)O(C1-C6 alkyl), C(?O)N(Rj)2, and SO2—Rh; wherein Rh is selected from C1-C6 alkyl, CH2-(heteroaryl including 5-10 ring atoms), CH2—(C6-C10 aryl), and C6-C10 aryl; and each occurrence of Ri is independently selected from H, C1-C6 alkyl, CH2-(heteroaryl including 5-10 ring atoms), CH2—(C6-C10 aryl), and C6-C10 aryl;
each occurrence of Rj is independently selected from H, F, OH, C1-C6 alkyl, C3-C6 cycloalkyl, NH2, OCO—(C1-C6 alkyl), OCO—(C3-C6 cycloalkyl), C1-C6 alkoxy, C1-C6 fluoroalkoxy, and cyano;
or Rj—C—Rj together form C3-C6 cycloalkyl or heterocyclyl including 3-6 ring atoms, in which one of the heterocyclyl ring atoms is selected from O; S(O)m and NRj?;
each occurrence of Rj? and Rk is independently selected from H, C1-C6 alkyl, —C(?O)H, —C(?O)Rm, C(?O)O(C1-C6 alkyl), C(?O)N(Rn)2, and SO2—Rm, wherein Rm is selected from C1-C6 alkyl, CH2-(heteroaryl including 5-10 ring atoms), CH2—(C6-C10aryl), and C6-C10aryl; and each occurrence of Rn is independently selected from H, C1-C6 alkyl, CH2-(heteroaryl including 5-10 ring atoms), CH2—(C6-C10 aryl), and C6-C10 aryl, and wherein the aryl and heteroaryl portion in Rm and Rn can be optionally substituted with 1-3 independently selected substituents F, C1-C6 alkyl, fluoro C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 fluoroalkoxy, or cyano;further wherein:(a) when each of A and B is a bond, and b is 0, then X has the following formula: —Y—[C(Ra)2]a—;
(b) when b is 0 or 1, then A and B cannot both be heteroatoms; and
(c) when A or B serves as the point of connection of X to the nitrogen ring atoms, then A or B cannot be a heteroatom;
R1 is:
(i) monocyclic or bicyclic heteroaryl including from 5-10 ring atoms, which is optionally substituted with from 1-3 Ro; wherein from 1-4 of the ring atoms are a heteroatom independently selected from O, N, N—H, N—Ro, and S;
(ii) C6-C10 aryl, which is optionally substituted with from 1-3 Ro;
(iii) C3-C10 cycloalkyl or C3-C10 cycloalkenyl, each of which is optionally substituted with from 1-6 Ro; or
(iv) hydrogen;
R4 is H or Ro and each occurrence of Ro is independently selected from the group consisting of halogen; C1-C6 alkyl; fluoro(C1-C6)alkyl; hydroxyl; hydroxy(C1-C4)alkyl; C1-C6 alkoxy; fluoro(C1-C6)alkoxy; (C1-C6 alkyl)C(O)—; (C1-C6 alkyl)NH—; (C1-C6 alkyl)2N—; —N*(Ro?)2, wherein Ro?—N*—Ro? together form a saturated ring having 5 or 6 ring atoms, in which 1 or 2 ring atoms are optionally a heteroatom independently selected from NH, N(C1-C6alkyl), O, or S; formyl; formyl(C1-C4) alkyl; cyano; cyano(C1-C4) alkyl; benzyl; benzyloxy; (heterocyclyl)-(C0-C6) alkyl, wherein the heterocyclyl portion includes 5 or 6 ring atoms, in which 1 or 2 of the ring atoms are a heteroatom independently selected from NH, N(alkyl), O, or S; phenyl; heteroaryl including from 5-6 ring atoms, wherein from 1-4 of the ring atoms are a heteroatom independently selected from O, N, N—H, N—Ro?, and S, each of which is optionally substituted with from 1-3 Ro?; SO2—(C1-C6)alkyl; SO—(C1-C6)alkyl; and nitro;
each occurrence of Ro? is independently selected from the group consisting of halogen; C1-C6 alkyl; fluoro(C1-C6)alkyl; hydroxyl; hydroxy(C1-C4)alkyl; C1-C6 alkoxy; fluoro(C1-C6)alkoxy; (C1-C6 alkyl)C(O)—; (C1-C6 alkyl)NH—; (C1-C6 alkyl)2N—; formyl; formyl(C1-C4) alkyl; cyano; cyano(C1-C4) alkyl; benzyl; benzyloxy; (heterocyclyl)-(C0-C6) alkyl, wherein the heterocyclyl portion includes 5 or 6 ring atoms, in which 1 or 2 of the ring atoms are a heteroatom independently selected from NH, N(C1-C6alkyl), 0, or S; phenyl; heteroaryl including from 5-6 ring atoms, wherein from 1-4 of the ring atoms are a heteroatom independently selected from O, N, N—H, N—(C1-C6 alkyl), and S; SO2—(C1-C6)alkyl; SO—(C1-C6)alkyl; and nitro;
R5 is selected from the group consisting of: hydrogen, halogen; C1-C6 alkyl;
fluoro(C1-C6)alkyl; hydroxyl; hydroxy(C1-C4)alkyl; (C1-C6 alkyl)C(O)—; formyl; formyl(C1-C4) alkyl; cyano; cyano(C1-C4) alkyl; benzyl; (heterocyclyl)-(C0-C6)alkyl, wherein the heterocyclyl portion includes 5 or 6 ring atoms, in which 1 or 2 of the ring atoms are a heteroatom independently selected from NH, N(C1-C6alkyl), O, or S; phenyl; heteroaryl including from 5-6 ring atoms, wherein from 1-4 of the ring atoms are a heteroatom independently selected from O, N, N—H, and S; SO2—(C1-C6)alkyl; SO—(C1-C6)alkyl; and nitro;
R2 is selected from H, F, Cl, CF3, CF2CF3, CH2CF3, OCF3, OCHF2, phenyl; or phenyl substituted with 1-3 Ro; and
R3 is H, F, or Cl.

US Pat. No. 10,428,026

PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS

GlaxoSmithKline Intellect...

1. A compound of Formula (I) or a pharmaceutically acceptable salt thereof:
wherein:
R1 is —C1-3alkyl or cyclopropyl;
R2 is H or —C0-3alkyl-C3-7cycloalkyl,
wherein said cycloalkyl is unsubstituted or substituted one, two, or three times by R5 which is the same or different;
R3 is —H, —C1-4alkyl, cyclopropyl, or —(CH2)pOR10;
R4 is phenyl, 5- or 6-membered heteroaryl, 9- to 11-membered heteroaryl, or —(CH2)n-phenyl,
wherein said phenyl is unsubstituted or substituted one, two, or three times by R7 which is the same or different; or said 5- or 6-membered heteroaryl is unsubstituted or substituted by—C1-3alkyl, —O—C1-3alkyl, or halo; or said 9 to 11-membered heteroaryl is unsubstituted or substituted by one, two, or three substituents independently selected from—C1-3alkyl-R8, —OCH3, —O—C2-3alkyl-R8, halo, oxo, —O—CF3, and —CN;p is 1 or 2;
n is 1 or 2;
R5 is halo, phenyl, —C1-6alkyl-R8, —CO2H, —OCH3, —O—C2-6alkyl-R8, —CN, —OH, or —NHR6;
R6 is —H, —C(O)OC(CH3)3, —C1-6alkyl, —C3-7cycloalkyl, 4- to 7-membered heterocyclyl, or—C2-3alkyl-O—C1-3alkyl,wherein said —C1-6alkyl or —C3-7cycloalkyl is optionally substituted one, two, or three times by fluoro;
R7 is —NR11R12, —C1-3alkyl, halo, —CO2R10, —CH2OH, —CH(R11)OR10, —C(O)C1-3alkyl, —CH(R10)NR11R12, —CN, —CHF2, —CF3, —OH, —OCHF2, —OCF3, —OCH3, —O—C2-6alkyl-R9, —C1-6alkyl-R9, or —O-piperidinyl;
R8 is —H, —OR10, —CO2C(CH3)3, or —NR11R12;
R9 is —H, —OR10, or —NR11R12;
R10 is —H or —C1-3alkyl;
R11 and R12 are each independently selected from —H, —C1-3alkyl, and —C1-3alkylNR13R14; or R11 and R12 are joined together with nitrogen to which they are attached, to form a 4- to 7-membered heterocyclyl group optionally substituted by one or two substituents independently selected from —C1-3alkyl, —OH, and F; and
R13 and R14 are each independently selected from —H, —C1-3alkyl, and —C(O)CH3.

US Pat. No. 10,428,019

CHIRAL AUXILIARIES

WAVE LIFE SCIENCES LTD., ...

1. A nucleic acid derivative comprising a chiral auxiliary, wherein the chiral auxiliary is represented by formula (II) and binds to a phosphorus atom of a phosphite moiety of the nucleic acid derivative through the oxygen atom of the chiral auxiliary, wherein the squiggly line represents the point of attachment to a phosphorus atom of a phosphite moiety of the nucleic acid derivative:
in which R1 and R2 independently represent a hydrogen atom, an unsubstituted or substituted alkyl group, an unsubstituted or substituted alkenyl group, an unsubstituted or substituted alkynyl group, an unsubstituted or substituted alkoxy group, an unsubstituted or substituted aralkyl group, or an unsubstituted or substituted aryl group;
R3 represents an unsubstituted or substituted aryl group or an unsubstituted or substituted alkyl group;
R4 and R5 independently represent a hydrogen atom, an unsubstituted or substituted alkyl group, an unsubstituted or substituted alkenyl group, an unsubstituted or substituted alkynyl group, an unsubstituted or substituted alkoxy group, an unsubstituted or substituted aralkyl group, or an unsubstituted or substituted aryl group;
Y represents -Y1-Y2-, where Y1 represents —C(R6)(R7)— in which R6 and R7 independently represent a hydrogen atom, an unsubstituted or substituted alkyl group, an unsubstituted or substituted alkenyl group, an unsubstituted or substituted alkynyl group, an unsubstituted or substituted alkoxy group, an unsubstituted or substituted aralkyl group, or an unsubstituted or substituted aryl group, or Y1 represents an unsubstituted or substituted o-aryldiyl group, and Y2 represents a single bond or —C(R8)(R9)— in which R8 and R9 independently represent a hydrogen atom, an unsubstituted or substituted alkyl group, an unsubstituted or substituted alkenyl group, an unsubstituted or substituted alkynyl group, an unsubstituted or substituted alkoxy group, an unsubstituted or substituted aralkyl group, or an unsubstituted or substituted aryl group.

US Pat. No. 10,428,010

PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES

Nouryon Chemicals Interna...

1. Process to convert cyclic alkylene ureas into their corresponding alkylene amines wherein the process is performed by reaction with an amine compound, and wherein the amine compound is chosen from the group of primary amines, cyclic secondary amines or bicyclic tertiary amines;wherein the cyclic alkylene urea reacts to the corresponding alkylene amine in accordance with below reaction

wherein R1 and R2 each independently are chosen from the group of hydrogen, an alkylene amine group of the formula X—R3—(NH—R3—)p—, or an alkoxy group of formula X—R3—(O—R3—)n—, or a group combining such alkylene amine and alkoxy units p and n, wherein optionally one or more units ˜N—R3—N˜ may be present as either one of the rings

and wherein each R3 independently is alkylene or substituted alkylene, X may be hydroxyl, amine, a linear or branched C1-C20 hydroxyalkyl or a linear or branched C1-C20 aminoalkyl group, n and p independently are 0 or at least 1, wherein when n and/or p is at least 1 the linear or branched C1-C20 hydroxyalkyl or C1-C20 aminoalkyl croup optionally contains one or more piperazine or alkylene urea groups.

US Pat. No. 10,427,993

PROCESS FOR RECOVERING BENZENE AND FUEL GAS IN AN AROMATICS COMPLEX

UOP LLC, Des Plaines, IL...

1. A process for the recovery of a benzene rich liquid stream and a light ends vapor stream in a xylene isomerization process from a feedstock, the process comprising:passing a feedstock into a deheptanizer in which the feedstock is separated into a deheptanizer vapor phase and a deheptanizer liquid phase, the deheptanizer vapor phase containing hydrocarbons with seven carbon atoms or less, and the deheptanizer liquid phase containing hydrocarbons with eight carbon atoms or more;
passing the deheptanizer vapor phase from the deheptanizer to a first separation zone;
separating the deheptanizer vapor phase in the first separation zone into a first liquid phase and a first vapor phase;
passing the first liquid phase from the first separation zone to a toluene recovery zone;
passing the first vapor phase from the first separation zone to a compression zone in which the first vapor phase is compressed and partially condensed to provide a compressed and partially condensed vapor phase;
passing the compressed and partially condensed vapor phase from the compression zone to a second separation zone;
separating the compressed and partially condensed vapor phase into the benzene rich liquid stream and a second vapor phase in the second separation zone, the second vapor phase being a light ends vapor stream;
recovering the light ends vapor stream;
recovering the benzene rich liquid stream; and
sending the benzene rich liquid stream to extraction.

US Pat. No. 10,427,991

CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION AND METHOD FOR OLEFIN OLIGOMERIZATION USING THE SAME

LG CHEM, LTD., Seoul (KR...

1. A catalyst system for olefin oligomerization comprising:at least one ligand compound represented by the following Chemical Formulas:

a chromium source; and
a support wherein the ligand compound is supported on the support.

US Pat. No. 10,427,990

RECYCLING SYSTEM AND PROCESS OF A METHANOL-TO-PROPYLENE AND STEAM CRACKER PLANT

TECHNIP FRANCE, Courbevo...

1. A process of producing hydrocarbons from a combined plant of a methanol-to-propylene (“MTP”) plant having at least a catalytic reactor and a steam cracker plant, the process comprising the steps of:flowing a stream having at least a portion of methanol and dimethyl ether into the catalytic reactor to produce a first intermediate process stream containing propylene, C4+ oxygenates, and gasoline;
purifying the first intermediate process stream from the catalytic reactor in a separation section of the MTP plant to produce an oxygenate recycle stream, a propylene stream, and a gasoline stream, wherein the gasoline stream comprises oxygenate-reduced C5 or heavier components;
flowing at least a portion of the gasoline stream from the separation section of the MTP plant to a steam cracking furnace, without passing through a catalytic reactor, that converts gasoline to ethylene by non-catalytic pyrolysis thereby producing a second intermediate process stream containing at least ethylene and a C4 di-olefin fraction; and
purifying the second intermediate process stream from the steam cracking furnace into a product process stream having ethylene in a cracker separation section.

US Pat. No. 10,427,988

METHOD AND INSTALLATION FOR TREATING A WASTE MIXTURE, INCLUDING SEPARATION AND COMPOSTING OF SAID MIXTURE

20. A plant for treating mixture of wastes (2), the latter being with heterogeneous sizes, shapes and consistencies, a non-negligible portion of the mass of the mixture of wastes (2) being formed by biodegradable wastes, and a non-negligible portion of the mass of the mixture being formed by non-biodegradable recyclable wastes (26), the treatment plant being characterized in that it comprises:a sorting machine (1), allowing separating the mixture of wastes (2) into a first fraction of wastes (13) the size of which is smaller than about 180 mm via a first series of separation orifices (7, 8), said first series of separation orifices (7, 8) comprising primary orifices (7) and secondary orifices (8) the size of which is larger than the size of the primary orifices (7) so that the mixture of wastes (2) is first brought into contact with the secondary orifices and then with the primary orifices (7), and into a residual second fraction of wastes (14),
a composting plant allowing subjecting the first fraction of wastes (13) to a composting process so as to compost, at least partially, the contained biodegradable wastes, characterized in that the composting plant comprises:
at least one first composting bay (3C) allowing subjecting the first fraction of wastes (13) to a first composting cycle so as to compost, at least partially, the biodegradable wastes of said first fraction of wastes (13), and to obtain a mixture of pre-composted wastes (2),
at least one bay (2C) for drying the mixture of pre-composted wastes (2), allowing obtaining a mixture of dried wastes (2),
means for separating the mixture of dried wastes (2) at least into a portion of heavy wastes (25) and a portion of light wastes, the portion of heavy wastes (25) being substantially formed by wastes with a volumetric mass heavier than the wastes of the portion of light wastes,
at least one second composting bay (3C) allowing subjecting the portion of light wastes to a second composting cycle so as to compost, at least partially, the contained biodegradable wastes, and obtain a mixture of refined wastes (28).

US Pat. No. 10,427,985

ENGINEERED MICRO-VOIDS FOR TOUGHENING CERAMIC COMPOSITES

Lockheed Martin Corporati...

1. A ceramic composite material comprising:a ceramic compound;
a plurality of shaping particles dispersed in the ceramic compound; and
a plurality of a first type of void spaces dispersed in the ceramic compound;
wherein:
the plurality of shaping particles are contained within the plurality of the first type of void spaces;
the shaping particles comprise nanostructures have a length to diameter ratio of less than or equal to 10 to 1 and a length of less than or equal to 500 nanometers; and
each of the plurality of the first type of void spaces is a closed cell.

US Pat. No. 10,427,984

SYSTEMS AND METHODS FOR CERAMIC MATRIX COMPOSITES

United Technologies Corpo...

1. A ceramic matrix composite formed by a process comprising:inserting a fiber tow in a mold;
introducing an aqueous solution comprising water, carbon nanotubes, and a binder into the mold;
freezing the aqueous solution, wherein the freezing the aqueous solution separates fibers within the fiber tow;
freeze drying the aqueous solution, wherein the freeze drying removes the water from the mold;
heat treating the fiber tow in the presence of a boron-bearing precursor and nitrogen gas to produce boron nitride nanotubes; and
processing the mold via at least one of slurry casting, chemical vapor infiltration, polymer infiltration and pyrolysis, or melt infiltration.

US Pat. No. 10,427,983

METHOD FOR MANUFACTURING PART MADE OF COMPOSITE MATERIAL

SAFRAN AIRCRAFT ENGINES, ...

1. A method of fabricating a part out of composite material, the method comprising:forming a fiber texture from refractory fibers;
impregnating the fiber texture for a first time with a first slip containing first refractory particles;
eliminating the liquid phase from the first slip that has impregnated the fiber texture so as to leave within said texture only the first refractory particles;
impregnating the fiber texture for a second time with a second slip containing second refractory particles;
eliminating the liquid phase from the second slip that has impregnated the fiber texture so as to leave within said texture only the second refractory particles and obtain a fiber preform filled with the first and second refractory particles; and
sintering the first and second refractory particles present in the fiber preform in order to form a refractory matrix in said preform;
wherein each of the first and second steps of impregnating the fiber texture comprises:
placing the fiber texture in a mold having an impregnation chamber including in its bottom portion a part made of porous material on which a first face of said texture rests, the impregnation chamber being closed in its top portion by a deformable impermeable diaphragm placed facing a second face of the fiber texture, said diaphragm separating the impregnation chamber from a compacting chamber;
injecting a slip containing a powder of refractory particles into the impregnation chamber between the second face of the fiber texture and the diaphragm;
injecting a compression fluid into the compacting chamber, the fluid exerting pressure on the diaphragm to force the slip to pass through the fiber texture; and
wherein each step of eliminating the liquid phase from the slip comprises draining the liquid phase of the slip that has passed through the fiber texture via the porous material part, the refractory particles being retained inside said texture by said porous material part.

US Pat. No. 10,427,982

METHOD OF CARBON COATING ON NANOPARTICLE AND CARBON COATED NANOPARTICLE PRODUCED BY THE SAME

KOREA INSTITUTE OF ENERGY...

1. A method including:supplying only nanoparticles and sources of any one or two or more combinations selected from a group which consists of a carbon source, a doping source, a carbon source capable of providing a doped element, and a waste plastic source into a high-temperature and high-pressure closed autoclave;
completely closing the high-temperature and high-pressure closed autoclave; and
forming a core-shell structure of the nanoparticle-a carbon shell or a core-shell structure of the nanoparticle-a carbon shell having the doped element by a single process under self-generated pressure and a first reaction temperature in the range of 500 to 850° C. by heating the autoclave,
wherein the method further comprises an additional functioning:
making the autoclave to a high-temperature and atmospheric state by removing gas from the autoclave in a state of high-temperature and high-pressure and thereafter, purging the autoclave by using an inert gas;
changing temperature up to a second reaction temperature for functioning and performing reaction while supplying a reaction gas; and
cooling the autoclave to room-temperature while purging the autoclave with an inert gas.

US Pat. No. 10,427,981

PIEZOELECTRIC MATERIAL, METHOD OF MANUFACTURING THE SAME, PIEZOELECTRIC ELEMENT, AND PIEZOELECTRIC ELEMENT APPLICATION DEVICE

Seiko Epson Corporation, ...

1. A piezoelectric material, containing:a first component which is a rhombohedral crystal in a single composition, in which a Curie temperature is Tc1, and which is composed of a lead-free-system composite oxide having a perovskite-type structure;
a second component which is a crystal other than the rhombohedral crystal in a single composition, in which a Curie temperature Tc2 is lower than Tc1, and which is composed of Li, K, Na, and Nb; and
a third component which is a crystal other than the rhombohedral crystal in a single composition similar to the second component, in which a Curie temperature Tc3 is equal to or higher than Tc1, and which is composed of K, Na, and Nb,
wherein when a molar ratio of the third component to the sum of the second component and the third component is set as ? and ?×Tc3+(1??)×Tc2 is set as Tc4, |Tc4?Tc1| is 50° C. or lower.

US Pat. No. 10,427,976

GLASS TUBE WITH INFRARED LIGHT REFLECTIVE COATING, METHOD FOR MANUFACTURING THE GLASS TUBE, HEAT RECEIVER TUBE WITH THE GLASS TUBE, PARABOLIC TROUGH COLLECTOR WITH THE HEAT RECEIVER TUBE AND USE OF THE PARABOLIC TROUGH COLLECTOR

SIEMENS CONCENTRATED SOLA...

1. A heat receiver tube for absorbing solar energy and for transferring absorbed solar energy to a heat transfer fluid located inside a core tube of the heat receiver tube, wherein:the heat transfer fluid is a thermo-oil;
the core tube comprises a core tube surface with a solar energy absorptive coating for absorbing solar absorption radiation of the sunlight;
the core tube is enveloped by an encapsulation with a glass tube with a glass tube wall, wherein a space between the core tube and the encapsulation is evacuated;
an inner surface of the glass tube wall comprises at least partially at least one infrared light reflective coating;
the infrared light reflective coating includes a transparent conducting coating comprising indium tin oxide, wherein the transparent conducting coating is configured to permit solar absorption radiation to impinge the core tube, and wherein the transparent conducting coating is configured to capture infrared radiation radiating from the core tube and direct the infrared radiation back to the core tube;
an intermediate layer of aluminum oxide arranged between the inner surface of the glass tube wall and the infrared light reflective coating;
an additional layer of aluminum oxide or silicon oxide covering the infrared light reflective coating, wherein the additional layer is between the infrared light reflective coating and the solar energy absorptive coating such that the additional layer is adjacent to the infrared light reflective coating and the space;
the core tube surface and the encapsulation are arranged in a distance between the core tube surface and the inner surface of the glass tube wall with the infrared reflective surface such, that the solar absorption radiation can penetrate the encapsulation with the infrared light reflective coating and can impinge the solar energy absorptive coating.

US Pat. No. 10,427,975

HIGH STRENGTH GLASS-CERAMICS HAVING PETALITE AND LITHIUM SILICATE STRUCTURES

Corning Incorporated, Co...

11. A glass-ceramic article comprising:Li2O;
SiO2;
Al2O3; and
a petalite crystalline phase,
wherein the article is transparent and has a transmittance of at least 85% for light in a wavelength range from 400 nm to 1,000 nm at a thickness of 1 mm, and
wherein the article has a fracture toughness of greater than 1.2 MPa·m1/2.

US Pat. No. 10,427,974

GLASS COMPOSITE FOR USE IN EXTREME ULTRA VIOLET LITHOGRAPHY

CORNING INCORPORATED, Co...

1. A glass composite for use in Extreme Ultra-Violet Lithography (EUVL), the glass composite comprising:a first silica-titania glass section; and
a second doped silica-titania glass section mechanically bonded to a surface of the first silica-titania glass section,
wherein the second doped silica-titania glass section has a thickness of greater than about 1.0 inch.

US Pat. No. 10,427,970

GLASS COATINGS AND METHODS TO DEPOSIT SAME

Owens-Brockway Glass Cont...

1. A method of producing a glass substrate, the method comprising:providing a silicate solution that includes a dissolved sodium silicate, the dissolved sodium silicate comprising a molar ratio of Na2O:SiO2;
adding a soluble calcium salt to the silicate solution to displace some of the sodium oxide in the dissolved sodium silicate with calcium oxide and to derive a wet precipitate that comprises a molar ratio of Na2O:CaO:SiO2;
removing solvent from the wet precipitate;
obtaining a dried glass precursor gel comprising a bulk amorphous oxide-based matrix having an inorganic network of primary constituent oxides, the primary constituent oxides comprising 60 mol % to 85 mol % silica (SiO2), 8 mol % to 18 mol % Na2O, and 5 mol % to 15 mol % CaO;
forming a powder or wire from the dried glass precursor gel;
melting the powder or wire with a gas stream to form molten droplets; and
depositing the molten droplets onto a mold to form the glass substrate.

US Pat. No. 10,427,969

METHOD OF MANUFACTURING OPTICAL FIBER

FUJIKURA LTD., Tokyo (JP...

1. A method of manufacturing an optical fiber comprising:melting and drawing an optical fiber preform to form a glass fiber in a drawer;
cooling the glass fiber while inserting the glass fiber into a tubular cooling device separated apart from the drawer with a gap therebetween and providing a temperature gradient to the glass fiber from an inlet end toward an outlet end thereof; and
lowering an inner wall temperature of the tubular cooling device below a temperature of the glass fiber and providing a pressure gradient in which a pressure increases in a direction from the inlet end toward the outlet end inside the tubular cooling device when cooling the glass fiber,
wherein an average pressure change dP/dL [Pa/m] in a moving direction of the glass fiber inside the tubular cooling device satisfies the following Formula (1) when a tube inner diameter of the tubular cooling device is defined as D [m] and a length of an internal space of the tubular cooling device in the moving direction of the glass fiber is defined as L [m]
0.001?(?D2/4)×dP/dL?0.03  (1).

US Pat. No. 10,427,968

METHOD FOR CUTTING GLASS

1. A method for cutting glass, comprising:providing a glass substrate, the glass substrate comprising at least one cutting surface, a plurality of micro-fractures being formed on the cutting surface;
coating a conductivity material on the cutting surface to form a conductivity material layer, the conductivity material layer having a capability for absorbing laser energy; and
irradiating the conductivity material layer by laser, causing the conductivity material layer to absorb the laser energy and transmit the laser energy to the glass substrate, thereby causing the laser energy to melt the glass substrate at the cutting surface to remove the plurality of micro-fractures.

US Pat. No. 10,427,966

GLASS FORMING APPARATUS AND METHOD

Samsung Electronics Co., ...

1. A glass forming apparatus comprising:a frame;
a moving mold including a plurality of curved surface-shaped cores, and configured to seat a material, the moving mold being moveable in a first direction;
a material supply unit disposed in the frame and configured to supply the material to the moving mold;
an unloading unit disposed opposite to the material supply unit in the first direction and configured to unload the material from the moving mold;
a preheating unit disposed between the material supply unit and the unloading unit, and configured to preheat the material seated on the moving mold;
a curved surface forming unit configured to form the material in a curved shape, wherein the curved surface forming unit includes:
a first mold disposed to face the moving mold forming a plurality of cavities formed between the moving mold and the first mold, and
a pneumatic device including a vacuum pump and configured to generate a vacuum pressure in the plurality of cavities to adhere the material to the plurality of curved surface-shaped cores; and
a cooling unit disposed between the curved surface forming unit and the unloading unit in the first direction and configured to cool the material in the curved shape transformed by the curved surface forming unit; and
a moving mold transfer unit configured to
move the moving mold through the preheating unit, the curved surface forming unit, and the cooling unit in the first direction.

US Pat. No. 10,427,965

METHOD FOR LOADING A BLANK COMPOSED OF FUSED SILICA WITH HYDROGEN, LENS ELEMENT AND PROJECTION LENS

CARL ZEISS SMT GMBH, Obe...

1. A method for loading a blank composed of fused silica with hydrogen,comprising:
loading the blank at a first temperature (T1) of less than 475° C. and a first hydrogen partial pressure (p1), and
further loading the blank at a second temperature (T2) of less than 300° C. and at a second hydrogen partial pressure (p2) which is different from the first hydrogen partial pressure,
wherein the first temperature and the second temperatures (T1, T2) are lower than a limit temperature (TL) at which a thermal formation of silane in the fused silica of the blank commences, and
wherein the loading and the further loading results in a silane content in all locations of the blank of less than 5×1014 molecules/cm3.

US Pat. No. 10,427,964

ENHANCED PROCESS FOR SELECTIVE SALT RECOVERY FROM WASTEWATER, WASTE SALTS, AND BRINES

Veolia Water Technologies...

6. A method of treating a waste brine that includes an alkali metal, sulfate and chloride and producing sulfate and chloride salt crystals comprising:concentrating the waste brine;
directing the concentrated waste brine to a Mirabilite crystallizer and producing via cooling crystallization hydrated sulfate salt crystals and a chloride-rich brine stream;
separating the hydrated sulfate salt crystals from the chloride-rich brine stream;
melting the hydrated sulfate salt crystals to form an aqueous sulfate solution or a slurry;
directing the aqueous sulfate solution or slurry to a sulfate crystallizer and crystallizing anhydrous sulfate salts from the aqueous sulfate solution or slurry to form sulfate salt crystals comprising sulfate and at least one alkali metal;
removing sulfate and suspended solids from the chloride-rich brine stream produced by the Mirabilite crystallizer by directing the chloride-rich brine stream from the Mirabilite crystallizer through a nanofiltration device which produces a permeate stream and a reject stream containing the sulfate removed from the chloride-rich brine stream;
directing the permeate stream from the nanofiltration device to a chloride crystallizer and producing chloride salt crystals comprising chloride and at least one alkali metal;
recycling the reject stream produced by the nanofiltration device to the Mirabilite crystallizer and mixing the reject stream with the waste brine directed into the Mirabilite crystallizer.

US Pat. No. 10,427,963

COMPOSITIONS AND METHODS FOR SCALE INHIBITION

Chevron U.S.A. Inc., San...

1. A method of inhibiting formation of scale on equipment in contact with a produced fluid containing at least a scale-forming divalent cation, the method comprising:injecting a solution comprising an alginate in an amount effective for the alginate to cross-link with the divalent cation into the produced fluid to form cross-linked alginate gel;
separating the cross-linked alginate gel in the produced fluid;
removing the cross-linked alginate gel from the produced fluid; and
redissolving the cross-linked gel thus returning it to a reusable form.

US Pat. No. 10,427,960

METHOD FOR IMPROVING PERFORMANCE OF FLUID PROCESSING SYSTEM BASED ON CRYSTALLIZATION PROMOTING MEDIUM

1. A fluid processing apparatus, comprising:a fluid inlet tube, N column bed units in parallel connection, and a fluid outlet tube;
each column bed unit containing a crystallization promoting medium (CPM) as a fluid processing medium for processing the fluid flowing therein;
said N column bed units are all in fluid communication with the fluid inlet tube;
wherein N is an integer greater than 1, and except a first one of the column bed units, each column bed unit is provided with one check valve upstream thereof in an inflow direction, each check valve being designed to open and close under a specific fluid pressure;
wherein when a total number of the check valves is two or more, at least two check valves have different opening pressure thresholds and different closing pressure thresholds from each other;
wherein the CPM is a medium having nucleation sites of an atomic size on its surface which promote formation of crystals of a substance, when the substance dissolved in a fluid flows through the CPM, the substance is to form a crystal and grow at the nucleation sites, when the crystal grows to a certain size, the crystal is flushed off by the fluid to release reusable nucleation sites.

US Pat. No. 10,427,959

METHOD AND SYSTEM FOR THE AUTONOMOUS SELF-LIMITING GENERATION OF CHLORINE DIOXIDE

TRUOX, INC., McClellan, ...

1. A method for the autonomous generation of safe self-limiting concentrations of chlorine dioxide for the treatment of process water, the method comprising:in a system comprising:
a pressurized vessel containing a hydantoin based free halogen donor having a solubility between 0.075 to 0.30 wt % at 20° C., a source of water in fluid contact with the inlet to the pressurized vessel, a manifold in fluid contact with the outlet from the pressurized vessel, a manifold in fluid contact with the outlet from the pressurized vessel for introduction of at least a chlorite donor, a reaction chamber in fluid contact with the manifold and with the process water to be treated;
introducing said source water to dissolve hydantoin based free halogen donor until 50 to 100% of saturation is achieved to form an aqueous solution of free halogen, introducing chlorite donor to the manifold, producing chlorine dioxide in the reaction chamber, and said chlorine dioxide is introduced to the process water.

US Pat. No. 10,427,958

CAPACITIVE DEIONIZATION CHARGE TRANSFER FROM ONE CAPACITOR SIMULTANEOUSLY TO MULTIPLE CAPACITORS

Lawrence Livermore Nation...

1. An energy transfer system comprising:a controller;
a first capacitor acting as a first electrode for the energy transfer system;
a second capacitor acting as a second electrode for the energy transfer system;
a first inductor for storing energy received from the first capacitor, and transferring the stored energy to the second capacitor;
a first plurality of electronic switches controlled by the controller for controlling a transfer of energy from the first capacitor to the first inductor and from the first inductor to the second capacitor; and
an additional energy transfer subsystem including:
a second plurality of electronic switches controlled by the controller;
a second inductor for receiving energy from the first capacitor; and
a third capacitor for receiving energy from the second inductor;
the controller configured to control at least a first switch from each of the first plurality of electronic switches and the second plurality of electronic switches to simultaneously charge the second inductor while the first inductor is charging, thus splitting energy received from the first capacitor between the first and second inductors, and at least a second switch from each one of the first and second pluralities of switches being controlled by the controller to simultaneously transfer energy from the second inductor to the third capacitor while energy is being transferred from the first inductor to the second capacitor.

US Pat. No. 10,427,957

OSMOTIC SEPARATION SYSTEMS AND METHODS

OASYS WATER LLC, Dover, ...

1. A system for osmotic extraction of a solvent from a first solution, comprising:(a) a reverse osmosis unit comprising:
a first chamber of the reverse osmosis unit in fluid communication with a source of the first solution;
a semi-permeable membrane of the reverse osmosis unit coupled to the first chamber of the reverse osmosis unit; and
a second chamber of the reverse osmosis unit coupled to the semi-permeable membrane of the reverse osmosis unit and configured for receiving a first portion of the solvent fluxed through the semi-permeable membrane of the reverse osmosis unit, thereby leaving a concentrated first solution in the first chamber of the reverse osmosis unit; and
(b) a first forward osmosis unit fluidly coupled to the reverse osmosis unit and comprising:
a first chamber of the first forward osmosis unit having an inlet in fluid communication with the first chamber of the reverse osmosis unit and configured for receiving the concentrated first solution;
a second chamber of the first forward osmosis unit having an inlet fluidly coupled to a source of a concentrated draw solution; and
a semi-permeable membrane of the first forward osmosis unit separating the first chamber of the first forward osmosis unit from the second chamber of the first forward osmosis unit and configured for osmotically separating a second portion of the solvent from the concentrated first solution, thereby forming a further concentrated first solution in the first chamber of the first forward osmosis unit and a dilute draw solution in the second chamber of the first forward osmosis unit;
(c) a separation system in fluid communication with the first forward osmosis unit and configured to separate the dilute draw solution into the concentrated draw solution and a solvent stream, the separation system comprising:
an inlet fluidly coupled to an outlet of the second chamber of the first forward osmosis unit for receiving the dilute draw solution therefrom; and
an outlet fluidly coupled to the second chamber of the first forward osmosis unit for introducing the concentrated draw solution to the first forward osmosis unit; and
(d) a second forward osmosis unit in fluid communication with the first forward osmosis unit and comprising:
a first chamber of the second forward osmosis unit having an inlet fluidly coupled to an outlet of the first chamber of the first forward osmosis unit and configured for receiving the further concentrated first solution from the first forward osmosis unit;
a second chamber of the second forward osmosis unit having an inlet fluidly connected to a source of a feed solution; and
a semi-permeable membrane of the second forward osmosis unit separating the first chamber of the second forward osmosis unit from the second chamber of the second forward osmosis unit and configured for osmotically separating a solvent from the feed solution, thereby diluting the concentrated first solution in the first chamber of the second forward osmosis unit and concentrating the feed solution in the second chamber of the second forward osmosis unit,
wherein the system for osmotic extraction of a solvent from a first solution further comprises a by-pass system in fluid communication with the reverse osmosis unit and the second forward osmosis unit and configured to return the diluted first solution from the outlet of the first chamber of the second forward osmosis unit to the inlet of the first chamber of the reverse osmosis unit.

US Pat. No. 10,427,956

ULTRASOUND AND ACOUSTOPHORESIS FOR WATER PURIFICATION

FloDesign Sonics, Inc., ...

1. An apparatus comprising:a flow chamber for housing a mixture of a fluid and a particulate;
at least two ultrasonic transducers coupled to the flow chamber, each ultrasonic transducer including a piezoelectric material, wherein each ultrasonic transducer is configured to be excited to generate a multi-dimensional acoustic standing wave at a different ultrasonic frequency and wherein each ultrasonic frequency is generated for a specific range of particle sizes and each ultrasonic transducer is configured to generate a pressure field that is Bessel function; and
at least one reflector located on an opposite side of the flow chamber from the at least two ultrasonic transducers.

US Pat. No. 10,427,955

IRRADIATION CHAMBER FOR LIQUID PURIFICATION APPARATUS, PURIFICATION APPARATUS AND BEVERAGE DISPENSER

Societe des Produits Nest...

1. An irradiation chamber for a liquid purification apparatus using ultraviolet light irradiation against reproduction of pathogenic microorganisms, the irradiation chamber comprising an inlet portion, an outlet portion, and a main portion having an elongated shape comprising a cylindrical part having a volume of 200 mL or less, the main portion connected to the inlet portion and the outlet portion by smoothly curved connecting portions each composed of curved surfaces having a curvature radius greater than or equal to a radius of the cylindrical part and greater than or equal to 0.5 cm, the irradiation chamber having an internal surface defining a cavity, the irradiation chamber comprising an ultraviolet light emitting member configured to irradiate a liquid in the irradiation chamber with ultraviolet light, the main portion having a shape enlarged compared to the inlet portion, and the internal surface of the irradiation chamber defining the cavity is a three dimensional rounded surface having no edge which forms a recess.

US Pat. No. 10,427,953

DITHIOCARBAMATE ALKALI METAL CROSS-LINKED RESIN FOR ADSORBING METAL IONS

King Fahd University of P...

1. An alkali metal cross-linked polymeric resin of formula (I)
n is a positive whole number in the range of 2 to 12;
X is a positive whole number in the range of 10 to 1,500; and
A1 forms a bond to A2.

US Pat. No. 10,427,952

WATER TREATMENT SYSTEM WITH PASSIVE HALOGEN BARRIER

HAMILTON SUNDSTRAND CORPO...

1. A water treatment system comprising:a space structure including,
a water line and a heat source connected with the water line for conveying water through the heat source to regulate temperature,
a sublimator connected with the water line to receive the water, the sublimator having a porous plate,
an adsorbent bed disposed in the water line,
a halogen-release material disposed in the water line downstream of, and adjacent to, the adsorbent bed, and
a passive halogen barrier disposed in the water line intermediate the adsorbent bed and the halogen-release material.

US Pat. No. 10,427,950

RECOVERY OF MINING PROCESSING PRODUCT USING BORONIC ACID-CONTAINING POLYMERS

Ecolab USA Inc., St. Pau...

1. A method for solid-liquid separation in a mining process, the method comprising:combining a first composition with a fluid stream of a mining process, the first composition comprising an uncrosslinked polysaccharide, the fluid stream having a pH of 8 or more;
combining a second composition with the fluid stream, the second composition comprising a boronic acid-containing polymer; and
separating a solid from the fluid stream.

US Pat. No. 10,427,948

SYSTEMS AND METHODS FOR AMMONIA RECOVERY, ACID GAS SEPARATION, OR COMBINATION THEREOF

7. An integrated process for separating or recovering basic gases comprising:(1) a first cycle comprising:
absorbing ammonia from an ammonia containing gas stream into an ammonia-lean solution, forming an ammonia-rich solution;
enriching said ammonia rich solution with one or more acid gases;
precipitating one or more ammonia-acid gas salts wherein said precipitating occurs during enriching, after enriching, or a combination thereof; and
separating at least a portion of said precipitate from any remaining liquid; and
(2) a second cycle comprising:
(a) absorbing ammonia from an ammonia containing gas stream into an ammonia-lean, an ammonia-ultra-lean, or ammonia-free solution, to form an ammonia-rich solution;
(b) enriching said ammonia-rich solution with one or more acid gases to form an ammonia-rich, acid gas rich solution; and
(c) concentrating said ammonia-rich, acid gas rich solution using one or more membranes to form a retentate and a permeate wherein said permeate is suitable for use as at least a portion of the ammonia-ultra-lean or ammonia-free solution in step (a) of the second cycle.

US Pat. No. 10,427,947

METHODS FOR PRODUCING CRYSTALLINE MICROPOROUS SOLIDS WITH THE RTH TOPOLOGY AND COMPOSITIONS DERIVED FROM THE SAME

California Institute of T...

1. A process for preparing a crystalline microporous solid of RTH topology, the process comprising hydrothermally treating a composition comprising:(a) (i) at least one source of silicon oxide and
(ii) at least one source of aluminum oxide, boron oxide, gallium oxide, hafnium oxide, iron oxide, tin oxide, titanium oxide, indium oxide, vanadium oxide, zirconium oxide, or combination or mixture thereof
in the presence of an organic complex comprising
(b) an imidazolium cation comprising methyl and ethyl groups and having a C/N+ ratio in a range of from 6:1 to 10:1; and
(c) an associated hydroxide or fluoride anion;
under conditions effective to crystallize the crystalline microporous solid of RTH topology.

US Pat. No. 10,427,946

MECHANOCHEMICAL SYNTHESIS OF IRIDIUM DIBORIDE AND IRIDIUM MONOBORIDE

University of Central Flo...

1. A composition comprising iridium diboride and iridium monoboride.

US Pat. No. 10,427,944

COMPOSITION FOR FORMING A SILICA BASED LAYER, SILICA BASED LAYER, AND ELECTRONIC DEVICE

Samsung SDI Co., Ltd., Y...

1. A composition for forming a silica based layer, the composition comprising polysilazane having polydispersity ranging from about 7.0 to about 13.6 and a solvent, andhaving viscosity ranging from about 1.35 centipoise (cps) to about 1.60 cps when measured at a measurement temperature of 25° C.

US Pat. No. 10,427,942

GRAPHENE DISPERSION PASTES, METHODS OF PREPARING AND USING THE SAME

ENERAGE INC., Wujie Town...

1. A method of preparing a graphene dispersion paste, comprising:mixing and stirring graphene sheets, a solvent and a polymer to form a pseudo-plastic non-Newtonian fluid, wherein each of the graphene sheets is consisting of 2 to 30 stacked graphene layers, and has a bulk density in a range from 0.005 to 0.05 g/cm3, a thickness in a range from 0.68 to 10 nm, and a lateral size in a range from 1 to 100 ?m; and
applying a pressure not less than 10 bar to the pseudo-plastic non-Newtonian fluid, allowing the pseudo-plastic non-Newtonian fluid pass through a slit of a clearance not greater than 1,000 ?m at least two times, then forming a graphene dispersion paste, wherein a viscosity of the pseudo-plastic non-Newtonian fluid passing through the slit is in a range from 10 to 10,000 cps, and a viscosity of the graphene dispersion paste is in a range from 50,000 to 350,000 cps.

US Pat. No. 10,427,941

DIRECT ULTRASONICATION PRODUCTION OF GRAPHENE SHEETS FROM COKE OR COAL

Nanotek Instruments, Inc....

1. A method of producing a isolated graphene sheets-containing ink composition, said method comprising:a) dispersing particles of said coke or coal powder in a liquid medium containing therein a surfactant or dispersing agent to produce a suspension and containing no oxidant or acid, wherein said coke or coal powder is selected from the group consisting of petroleum coke, coal-derived coke, mesophase coke, synthetic coke, leonardite, anthracite, lignite coal, bituminous coal, or natural coal mineral powder, and combinations thereof; and
b) exposing said suspension to ultrasonication at an energy level for a sufficient length of time to produce said isolated graphene sheets in said liquid medium
c) adding a property modifier or chemical species to produce said isolated graphene sheets-containing ink composition, wherein said addition can occur before, during or after exposing said suspension to ultrasonication.

US Pat. No. 10,427,939

METHOD FOR PRODUCING SPHERICAL ALUMINUM NITRIDE POWER

LG Chem, Ltd., (KR)

1. A method for producing a spherical aluminum nitride powder, comprising:(i) mixing an aluminum (Al) precursor and a flux in a solvent to produce a mixed solution;
(ii) spray-drying the mixed solution produced in step (i) to form a spray-dried powder comprising the Al precursor and the flux;
(iii) mixing the spray-dried powder and a carbon-based material to form a mixture;
(iv) heat treating the mixture of step (iii) in a nitrogen atmosphere to form a heat-treated compound; and
(v) decarbonizing the heat-treated compound of step (iv) in an air atmosphere to produce a spherical aluminum nitride powder,
wherein the flux is at least one selected from the group consisting of Cu2O, TiO2, Bi2O3, and CuO, or a mixture of at least one selected from the group consisting of Cu2O, TiO2, Bi2O3, and CuO and at least one selected from the group consisting of CaF2 and Y2O3.

US Pat. No. 10,427,937

METHOD FOR PRODUCING A MULTILAYER MEMS COMPONENT, AND CORRESPONDING MULTILAYER MEMS COMPONENT

Robert Bosch GmbH, Stutt...

1. A method for manufacturing a multi-layer MEMS component, the method comprising:providing a multi-layer substrate that includes a monocrystalline carrier layer, a monocrystalline functional layer with a front side and a back side, and a bonding layer located between the back side and the carrier layer;
growing a first polycrystalline layer over the front side of the monocrystalline functional layer;
removing the monocrystalline carrier layer; and
growing a second polycrystalline layer over the back side of the monocrystalline functional layer.

US Pat. No. 10,427,936

METHOD OF PROCESSING NANO- AND MICRO-PORES

Guangdong University of T...

1. A method of processing nano- or micro-pores, comprising:step 1: washing a substrate with deionized water, and cleaning a surface of the substrate with a plasma cleaner;
step 2: spin-coating photoresist on the substrate, and then exposing the substrate and developing to form the substrate with a pattern;
step 3: depositing micro-nano metal particles on the surface of the substrate; wherein the micro-nano metal particles are centered on a magnetic core, and a surface of the magnetic core is plated with a metal nano-particle coating composed of a plurality of gold, silver or aluminum nanoparticles;
step 4: removing the photoresist and maintaining dot arrays of the micro-nano metal particles deposited on the surface of the substrate;
step 5: exposing the substrate with surface deposited with the micro-nano metal particles using laser irradiation and applying a strong uniform magnetic field in a reaction chamber; wherein the magnetic core in the micro-nano metal particles guided by the strong uniform magnetic field drives the micro-nano metal particles to directionally move on the substrate, so that the substrate is processed to form processed structures;
step 6: after the processed structures being formed with nano- or micro-pores of target pore size, shape and depth, stopping the laser irradiation and removing the strong uniform magnetic field to obtain a finished product.

US Pat. No. 10,427,935

MANUFACTURING METHOD FOR SEMICONDUCTOR STRUCTURE

UNITED MICROELECTRONICS C...

1. A manufacturing method for a semiconductor structure, comprising:forming a dielectric structure on a substrate;
forming a metal ring in a MEMS region, wherein the metal ring is embedded in the dielectric structure; and
forming a cavity by a removing method comprising etching a portion of the substrate and a portion of the dielectric structure to expose the metal ring, and then etching another portion of the dielectric structure using the metal ring as an etching mask.

US Pat. No. 10,427,934

THERMAL MANAGEMENT USING MICROELECTROMECHANICAL SYSTEMS BIMORPH CANTILEVER BEAMS

United States of America ...

1. A cooling structure for a heat source, the cooling structure comprising:a plurality of beams having a first end and terminating at a second end, the plurality of beams having a plurality of different lengths defined between the first and second ends, each beam formed at least in part of a first conducting material having a first thermal coefficient of expansion and a second conducting material having a second thermal coefficient of expansion, where the first thermal coefficient of expansion is different from the second thermal coefficient of expansion,
the first end of each beam thermally connected to the heat source, such that heat generated by the heat source is conducted along the length of the beam to the second end of each beam,
where the heat conducted through each beam causes each beam to deflect as the first and second materials expand differently due to the difference in the first and second thermal coefficients of expansion,
where characteristics of each beam are selected such that the second end of each beam makes thermal contact with a heat sink as a temperature of the heat source increases, the beam thereby conducting heat away from the heat source to the heat sink and assisting to lower the temperature of the heat source;
wherein the heat source and the heat sink are connected to a substrate and the beam extends across the substrate between the heat source and the heat sink; and
wherein the plurality of beams include a first plurality of beams positioned at an intermediate location of the cooling structure, a second plurality beams and a third plurality of beams positioned on either side of the first plurality of beams, and wherein the second and third plurality of beams are shorter in length relative to the first plurality of beams.

US Pat. No. 10,427,933

MICROELECTROMECHANICAL SENSOR DEVICE WITH REDUCED STRESS-SENSITIVITY AND CORRESPONDING MANUFACTURING PROCESS

STMicroelectronics S.r.l....

1. A process for manufacturing a MEMS device, the process comprising:coupling a sensor wafer to a supporting wafer, the sensor wafer including semiconductor material and including a sensor die integrating a micromechanical detection structure and a sensor frame;
separating the sensor die from the sensor frame, the sensor frame being arranged around the sensor die;
after separating the sensor die from the sensor frame, electrically and mechanically coupling at least one conductive element to the sensor die and the sensor frame, wherein the sensor frame supports the sensor die only by the at least one conductive element;
coupling a cap wafer to a surface of the sensor frame; and
mechanically decoupling the sensor die from the supporting wafer.

US Pat. No. 10,427,932

HERMETICALLY SEALED MEMS DEVICE AND ITS FABRICATION

TEXAS INSTRUMENTS INCORPO...

1. A hermetic package, comprising:a substrate having a surface;
a microelectromechanical system (MEMS) structure on the surface, the MEMS structure having a first height;
a cap hermetically sealed to the substrate, the cap forming a cavity over the MEMS structure; and
a vertical stack of metal layers adhering to the surface and to the cap, the cap attached to the surface by the stack, the stack having a continuous outline surrounding the MEMS structure while spaced from the MEMS structure by a distance, and the stack having: a first bottom metal seed film adhering to the substrate; a second bottom metal seed film adhering to the first bottom metal seed film, the first and second bottom metal seed films having a first width and a first common sidewall; a first top metal seed film adhering to the cap; a second top metal seed film adhering to the first top metal seed film, the first and second top metal seed films having a second common sidewall and a second width smaller than the first width; and a metal layer including gold-indium intermetallic compounds, the metal layer encasing the first and second bottom metal seed films and the first and second top metal seed films and the first and second common sidewalls and having a second height greater than the first height.

US Pat. No. 10,427,931

SELECTIVE CONDUCTIVE COATING FOR MEMS SENSORS

Analog Devices, Inc., No...

1. A microelectromechanical systems (MEMS) sensor, comprising:a first capacitor plate with a top, bottom, and side surface all covered with a metal, the first capacitor plate comprising a semiconductor material;
a second capacitor plate in-plane with the first capacitor plate in a first plane, spaced apart from the first capacitor plate, and covered with the metal; and
a third capacitor plate covered with the metal and spaced apart from the first capacitor plate in a second plane different from the first plane.

US Pat. No. 10,427,930

MEMS SENSOR WITH HIGH VOLTAGE SWITCH

InvenSense, Inc., San Jo...

1. A microelectromechanical systems (MEMS) device comprising:an integrated circuit layer; and
a MEMS switch on an upper surface of the integrated circuit layer and operable to switch a signal within a plane that is parallel to the upper surface of the integrated circuit layer, wherein the MEMS switch comprises:
a post anchor;
a flexible MEMS arm coupled to the post anchor, wherein the flexible MEMS arm is flexible within the plane;
an actuator electrode located in the plane of the flexible MEMS arm; and
a contact electrode located in the plane of the flexible MEMS arm.

US Pat. No. 10,427,929

FORMING A EUTECTIC BOND BETWEEN A WAFER HAVING AN ANTI-STICTION COATING AND A CAP WAFER

NXP USA, Inc., Austin, T...

1. A method comprising:providing a first semiconductor substrate;
forming a metal layer over the first semiconductor substrate;
forming an anti-stiction coating layer on the metal layer;
providing a second semiconductor substrate;
forming a roughened germanium layer over the second semiconductor substrate, wherein said forming the roughened germanium layer comprises:
forming polycrystalline silicon clusters over the second semiconductor substrate;
depositing a first layer comprising silicon and germanium over the polycrystalline silicon clusters; and
depositing a second layer comprising germanium over the first layer;
contacting the roughened germanium layer to the anti-stiction coating layer; and
after contacting the roughened germanium layer to the anti-stiction coating layer,
applying sufficient pressure to the second semiconductor substrate for at least a portion of the roughened germanium layer to penetrate the anti-stiction coating layer and come into contact with the metal layer, and
forming a mechanical bonding material between the first substrate and the second substrate, wherein
the forming a mechanical bonding material includes applying heat to the roughened germanium layer and the metal layer, and
the bonding material comprises a metal of the metal layer and germanium of the germanium layer.

US Pat. No. 10,427,928

FLUID INTERFACE TO RECEIVE REMOVABLE CONTAINER

LIFE TECHNOLOGIES CORPORA...

1. A fluidic interconnect comprising:a first interface including a liquid port, a gas port, and a cradle;
a second interface including a liquid port, a gas port, and a swing bar to engage the cradle, a weight of a container attached to one of the first or second interfaces to drive the liquid port of the first interface into connection with the liquid port of the second interface and the gas port of the first interface into connection with the gas port of the second interface:
wherein the first interface is coupled to an instrument and the second interface is coupled to the container, the cradle and swing bar engaging further from the instrument than the liquid and gas ports.

US Pat. No. 10,427,927

METHOD FOR FILLING A CONTAINER WITH A LIQUID

Leibinger GmbH, Teningen...

1. A method for filling a bottle with a liquid, the method comprising:providing a cap comprising an axial through bore and a radial opening that extends in a radial direction through the cap, the radial opening having a radial inward end opening into the axial through bore and further having a radial outward end;
providing a balloon body that is liquid-tight relative to the liquid and gas-tight, the balloon body extending through the axial through bore, the balloon body comprising an upper circumferential rim, wherein the balloon body is connected seal-tightly to the cap with the upper circumferential rim above the radial inward end of the radial opening, and the balloon body further having a balloon bottom end extending downwardly away from the cap;
providing an elongate support associated with the balloon body and connected to the cap;
inserting the balloon bottom end and the elongate support into the bottle through a container opening of the bottle;
positioning the cap in a first position at a spacing above a top face of a rim of the container opening so that a ring-shaped intermediate gap is defined between a bottom side of the cap and the top face;
inflating the balloon body with an expansion medium until the balloon body fills out an interior of the bottle to thereby force out air contained in the interior of the bottle through the ring-shaped intermediate gap;
subsequently fluid-tightly fitting the cap in a second position on the top face of the container opening;
creating an intermediate space between an outer surface of the balloon body and an inner wall of the bottle by allowing the expansion medium to escape from the balloon body;
supplying the liquid through the radial opening and through the axial through bore into the intermediate space.

US Pat. No. 10,427,926

BOOM LOAD MONITORING

Altec Industries, Inc., ...

1. A boom load monitoring system, comprising;a first sensor that monitors a lower boom angle, the lower boom angle being between a lower segment of a boom and a substantially horizontal plane;
a second sensor that monitors an upper boom joint angle, the upper boom joint angle being between the lower segment and an upper segment of the boom;
an upper boom hydraulic cylinder disposed between the lower segment of the boom and the upper segment of the boom;
a third sensor that monitors a hydraulic fluid pressure of the upper boom hydraulic cylinder configured to pivotally raise and lower the upper segment with respect to the lower segment;
a controller having a non-transitory memory and a processor for processing software instructions stored in the memory, the controller being communicatively coupled with the first sensor, the second sensor, and the third sensor, wherein the controller performs the steps of:
determining a load limit based on the lower boom angle, the upper boom joint angle, and predetermined load values stored in the memory;
tracking the lower boom angle over time and the upper boom angle over time;
determining a current state of motion of the upper boom cylinder based upon the tracking of the lower boom angle over time and the upper boom angle over time;
determining a current friction-correction factor based at least in part on the determined current state of motion of the upper boon cylinder;
applying the current friction-correction factor to the hydraulic fluid pressure measured by the third sensor to determine an effective load on the boom; and
determining whether the effective load exceeds the load limit; and
an alert indicator communicatively coupled to the controller for producing an alert when the effective load exceeds the load limit.

US Pat. No. 10,427,924

INDUSTRIAL TRUCK COMPRISING A DEVICE FOR REDUCING VIBRATIONS

1. An industrial truck comprising:a mast;
a load-carrying apparatus capable of being moved upwards and downwards thereon and which has at least one load-receiving means for receiving a load that is to be transported and a support structure connecting the load-receiving means to the mast, the load-receiving means having a load-carrying arrangement connected to the support structure; and
a device for reducing vibrations,wherein the device for reducing vibrations has at least one load support, which covers a top region of the load-carrying arrangement, and a damping system that is configured to influence the at least one load support towards a target rest position, wherein a load received by the load-carrying apparatus can be supported on the at least one load support, wherein the at least one load support is provided so as to be movable to a limited extent on the load-carrying arrangement such that the at least one load support can perform vibration-reducing movements relative to the load-carrying arrangement,wherein the industrial truck is designed as a sideloader, which has a load-carrying fork having load-carrying arms comprising rollers as the load-carrying arrangement,
wherein the damping system is arranged vertically on the load-carrying arms and is connected to the at least one load support via a lever arm,
wherein the load-carrying arms are positioned or can be oriented transversely to a straightforward direction of travel of the industrial truck, the load support being capable of performing vibration-reducing movements along the load-carrying arms and therefore transversely to the straightforward direction of travel of the industrial truck.

US Pat. No. 10,427,923

CENTRAL ROTATING COLUMN WITH HORIZONTAL HYDRAULICALLY DRIVEN MOVEMENT ARRANGED IN A DUMP BODY AND WATER TRUCK BODY EXCHANGE SYSTEM HAVING TWO ADJACENT WORKING AREAS, COMPRISING AN INTERNAL HYDRAULIC TANK AND WITH AN INTERNAL VERTICAL TRAVELING SUPPORT ATT

1. A central rotating column made of structural steel, having a horizontal hydraulically-driven movement, arranged in a dump body and water truck body exchange system, able to access two adjacent working areas, and featuring a hydraulic oil tank in an interior of said central rotating column; the central rotating column includes a vertical traveling support arm vertically traveling by means of a hydraulic cylinder, also including a 90° swing movement; the central rotating column rotates on a vertical axis mounted on a 180° rotating turntable, the turntable includes a hydraulic motor driven crown and pinion assembly being an integral part of the base of the central rotating column comprising: an adjustable vertical safety mechanical lock activated by an external locking lever preventing accidental downward travel of the vertical traveling support arm; a mechanical spring-actuated automatic safety lock adjusting the horizontal hydraulically-driven movement of the central rotating column; an automatic rotation lock preventing the central rotating column from rotating during lifting operations; the hydraulic motor driven crown and pinion assembly allowing 360° rotation of the central rotating column; a structural steel accessory attached to the vertical traveling support arm to enable operation with water tank bodies; and a load sensor preventing the horizontal hydraulically-driven movement of the central rotating column under load.

US Pat. No. 10,427,922

Z-DRIVE SHIPPING LOCK FOR STORAGE LIBRARY ROBOTIC ASSEMBLY

ORACLE INTERNATIONAL CORP...

1. A locking subsystem of a drive assembly, comprising:a spring-loaded ratchet pawl comprising a portion thereof movable between at least first and second pawl positions, wherein the spring-loaded ratchet pawl ratchet pawl is configured to be disengaged from between adjacent gear teeth of the drive assembly when in the first pawl position to allow rotational movement of the drive assembly in both of first and second opposing rotational directions, wherein the spring-loaded ratchet pawl ratchet pawl is configured to engage between adjacent gear teeth of the drive gear of the drive assembly in the second pawl position to disallow rotational movement of the drive assembly in the first rotational direction and allow rotational movement of the drive assembly in the opposing second rotational direction, wherein the spring-loaded ratchet pawl is in a first state of deflection in the first pawl position, wherein the spring-loaded ratchet pawl is in a second state of deflection in the second pawl position, and wherein the second state of deflection is less than the first state of deflection;
a handle movable between at least first and second handle positions; and
a cam member rigidly secured to the handle and movable between the first and second handle positions, wherein the cam member urges the spring-loaded ratchet pawl into the first pawl position in the first handle position, and wherein the spring-loaded ratchet pawl moves into the second pawl position in the second handle position.

US Pat. No. 10,427,921

SLACK LINE DETECTION SYSTEMS FOR WINCHES

Ingersoll-Rand Company, ...

1. A winch comprising:a first end frame and a second end frame;
a drum located between and rotatably coupled to the first and second end frames and configured to rotate to wind or unwind a cable;
a brake configured to resist rotation of the drum when engaged;
a switch configured to cause the brake to engage the drum when the switch is activated;
a slack arm frame engaging the cable and including a first lever arm and a second lever arm, the first lever arm pivotally coupled to the first end frame and the second lever arm pivotally coupled to the second end frame, wherein the slack arm frame is configured to pivot between a first position when the cable is taut and a second position when the cable is slack;
a cam having an arcuate camming surface coupled to the slack arm frame and the first end frame, with the first end frame located between the slack arm frame and the cam;
a mounting bracket coupling the switch to the first end frame, wherein the mounting bracket is adjustable between a plurality of locations on the first end frame by loosening and tightening a single fastener, each of the plurality of locations positioning the switch at a different distance from the axis;
a first drop stop attached to the first lever arm and extending toward the first end frame, the first drop stop being configured to directly contact the first end frame when the slack arm frame pivots from the first position to the second position to prevent further pivoting of the slack arm frame.

US Pat. No. 10,427,920

METHOD OF DETECTING A WORN LINK IN A CHAIN, AND A HOIST ARRANGEMENT

1. A method of detecting a worn link in a chain of a hoist arrangement operated with an electric drive system, the method comprising the step of:measuring a first signal of the electric drive system of the hoist arrangement while driving the hoist and detecting a peak crossing of a certain threshold level in the measured first signal, said peak in the measured first signal representing the worn link in the chain,
said method further comprising at least one of the following:
that the measured first signal is a load signal of the electric drive system of the hoist and peaks above a certain threshold level are detected; and that
the measured first signal is a speed signal of the electric drive system of the hoist and peaks crossing a certain threshold level are detected.

US Pat. No. 10,427,919

APPLICATION AND METHOD FOR POSITIONING AND ORIENTATING A LOAD

1. An apparatus for positioning and orientating a load, the apparatus comprising:a support structure movable in a first direction, the support structure establishes an area within which the load can be positioned and orientated;
a tendon system comprising:
at least six winches directly mounted on the support structure; and
at least six tendons, a first end of each of the at least six tendons being connected to a respective one of the at least six winches;wherein the apparatus further comprises:a lifting mechanism mounted on the support structure and movable in a second direction which is perpendicular to the first direction, the lifting mechanism comprising a further tendon;
attachment means whereto the load is attachable to suspend from above, the attachment means being connected to a second end of each of the at least six tendons and to a free end of the further tendon; and,
a control module being capable of synchronously and independently operating:
over the at least six winches so as to adjust the free length of and/or tension supported by the tendon connected to the respective winch,
the support structure so as to control its movement in the first direction, and
the lifting mechanism so as to control its movement in the second direction and the lifting mechanism so as to adjust the free length of and/or tension supported by the further tendon connected to the lifting mechanism,
whereby the apparatus provides control of the load in the six degrees of freedom; wherein the control module is configured to translate an instruction regarding the orientation and/or the position of the load in an actuation of the at least six winches, of the lifting mechanism and of the support structure, such that at least 51% of the load is sustained by the lifting mechanism and the load is suspended from the further tendon which is substantially vertical.

US Pat. No. 10,427,918

MECHANICAL CLAMPING ASSEMBLY

1. An apparatus for lifting objects, the apparatus comprising:two or more tines each having first and second ends, the first ends defining an attachment point, the second ends defining hooked portions;
two or more lines, the attachment point of each tine is attached to a first end of one of the two or more lines; and
a spreader, each of the two or more tines pivotally secured to the spreader between the first and second ends thereof;
wherein the two or more tines include an inner surface facing the spreader, the attachment point and hooked portion both protruding inwardly toward the spreader from the inner surface.

US Pat. No. 10,427,914

ELEVATOR SYNCHRONOUS DOOR KNIFE

OTIS ELEVATOR COMPANY, F...

1. An elevator synchronous door knife, comprising a track frame disposed on a door motor back plate and a bottom plate disposed on a hanging plate, wherein the back of the bottom plate is hinged with a stop arm, a transmission arm linked with a door motor driving mechanism and a lock plate buckled with a lock hook disposed on a lift car, a front end of the stop arm is provided with a guide wheel fitting in with the track frame, and upper and lower portions of the front of the bottom plate are respectively rotationally connected with an upper rotating arm and a lower rotating arm, characterized in that: the upper rotating arm (2) is linked with the transmission arm (9) through a draw bar (7), one end of the upper rotating arm (2) and the lower rotating arm (2?) is rotationally connected with a first blade (3), the other end of the upper rotating arm and the lower rotating arm is rotationally connected with a movable plate (4), to form a four-bar linkage, upper and lower portions of the movable plate are respectively rotationally connected with an upper unlock rotating arm (6) and a lower unlock rotating arm (6?), the upper unlock rotating arm and the lower unlock rotating arm are movably connected with a second blade (5), and the upper unlock rotating arm further abuts against the lock plate (10) to drive the lock plate to be unlocked or locked up.

US Pat. No. 10,427,913

LINEAR PROPULSION SYSTEM

OTIS ELEVATOR COMPANY, F...

1. A linear propulsion machine comprising:a first stator, the stator including a plurality of teeth, each of the teeth having a magnetic pole; and
a first mover adjacent to the first stator and moveable in a linear direction along the first stator, the teeth of the first stator and the first mover defining a gap, the mover including:
a plurality of spaced apart ferromagnetic strata;
a plurality of slots, each of the slots adjacent to at least one of the strata;
a plurality of wire coils, each coil disposed in at least one slot, the coils having an activated state and a deactivated state; and
a plurality of permanent magnet layers, each permanent magnet layer sandwiched between two of the strata and disposed inside one of the plurality of coils, the plurality of permanent magnet layers mounted on the mover to have reversed polarities with consecutive permanent magnet layers in a longitudinal direction along the mover,
wherein each coil is disposed substantially perpendicularly to the direction of magnetic flux of the permanent magnet layer around which the coil is wound, wherein the teeth or the permanent magnet layer is disposed at an angle in the range of about ?60° to about 60° from a plane substantially perpendicular to the direction of thrust on the first mover generated by the interaction of the first mover with the first stator;
wherein each permanent magnet layer is comprised of first and second permanent magnets, the first permanent magnet disposed between the stator and the second magnet, wherein the first permanent magnet is a bonded magnet.

US Pat. No. 10,427,911

DAMPER UNIT FOR AN ELEVATOR

INVENTIO AG, Hergiswil N...

1. A damper unit for an elevator, the damper unit being arranged on an elevator car of the elevator for reducing vibrations of the elevator car during a standstill, comprising:an acting element, in an idle position, being spaced apart from a guide rail of the elevator, the acting element, in an active position, being connected slip-free to the guide rail; and
force transmitting elements attached to the acting element for damping movements of the elevator car in the active position of the acting element to reduce vibrations of the elevator car, where the force transmitting elements include a ram that extends in a horizontal direction with a free end on which the acting element is arranged, and the force transmitting elements further include at least one shock damper hinged to a housing, wherein in the idle position the at least one shock damper is transversely oriented to the ram, and the at least one shock damper is configured to attenuate vertical vibrations of the elevator car through changes in length.

US Pat. No. 10,427,910

DISPLAY LANGUAGE ARRANGEMENT

Kone Corporation, Helsin...

1. A method for applying user preferences for at least one public display comprising:detecting at least one mobile device in a vicinity of said at least one public display;
establishing communication between said at least one public display and said at least one mobile device, said communication being established using one or more signals having a communication range covering at least an area in which content output by said at least one public display is visible;
receiving at least one indication of at least one user preference from each of said at least one mobile device by
receiving an identification from said at least one mobile device,
transmitting a request to a server storing one or more user preferences in association with said identification, and
receiving said at least one indication of said at least one user preference as a response to said request;
determining at least one user preference for said at least one public display based on said at least one indication; and
applying said determined at least one user preference to said at least one public display, said at least one user preference including a preferred language of operation, and said at least one indication received from each of said at least one mobile device indicating more than one language of operation in order of preference.

US Pat. No. 10,427,909

USER-CONTROLLED ELEVATOR ALLOCATION FOR INDEPENDENT SERVICE

OTIS ELEVATOR COMPANY, F...

1. A system for allocating elevator use based on an individual request, the system comprising:a request module that receives a reservation request of an elevator car from a user;
an allocation module that identifies a reserved elevator car based on the reservation request; and
a mechanical control module that moves the reserved elevator car in response to commands provided by the user and the reservation request;
wherein the reservation request specifies a time parameter for reservation request, the time parameter including at least one of a day and a time the reserved elevator car is requested;
wherein the reservation request includes a location where the reserved elevator car is desired;
the reservation request specifies an independent service that dedicates a reserved elevator car for operation by the user.

US Pat. No. 10,427,908

EMERGENCY MODE OPERATION OF ELEVATOR SYSTEM HAVING LINEAR PROPULSION SYSTEM

OTIS ELEVATOR COMPANY, F...

1. A method, comprising:detecting, by an elevator controller, a fault within an elevator system;
utilizing, by the elevator controller, the fault to disable a drive control portion of the elevator controller and activate a drive urgent stop control portion of the elevator controller;
generating, by the drive urgent stop control portion of the elevator controller, a signal based on at least one of a speed estimation, a velocity profile, and feedforward information; and
applying, by the elevator controller, the signal to an inverter connected to a linear propulsion system to execute the urgent stop of an elevator car of the elevator system;
the linear propulsion system comprising a primary portion including a plurality of coils configured to receive power from the inverter and a secondary portion including permanent magnets, one of the primary portion and the secondary portion mounted to the elevator car.

US Pat. No. 10,427,905

ACCUMULATION DEVICE

Fuji Seal International, ...

1. An accumulation device, comprising:an infeed unit configured to feed in a substrate;
an outfeed unit configured to feed out the substrate;
a tensioning unit disposed toward upstream in a transporting direction of the substrate between the infeed unit and the outfeed unit, the tensioning unit being configured to apply predetermined tensile force to the substrate;
an accumulation unit disposed downstream of the tensioning unit in the transporting direction of the substrate between the infeed unit and the outfeed unit, the accumulation unit being configured to accumulate a surplus of the substrate generated by a difference between a substrate infeed rate of the infeed unit and a substrate outfeed rate of the outfeed unit; and
a controller configured to control an operation of each of the infeed unit, the outfeed unit, and the accumulation unit,
wherein
the tensioning unit includes a plurality of rotatable fixed rollers spaced from each other and arranged in parallel to each other, and at least one rotatable movable roller disposed in parallel to the fixed rollers, the at least one rotatable movable roller being movable toward and away from the fixed rollers, the substrate being transported while being wound alternately around the fixed rollers and the at least one movable roller,
the tensioning unit is configured to apply the predetermined tensile force to the substrate by a force acting onto the movable roller in a direction away from the fixed rollers, and
the controller is configured to maintain a constant position of the movable roller with respect to the fixed rollers of the tensioning unit.

US Pat. No. 10,427,904

METHOD FOR PRODUCING FILM AND METHOD FOR WINDING OFF FILM

SUMITOMO CHEMICAL COMPANY...

1. A method for producing a film, said method comprising the steps of:taking up a film by a first step of winding the film on an outer peripheral surface of a core while oscillating the core in a rotation axis direction, such that the film is in a state of being distorted in a wavelike manner in the rotation axis direction; and
a second step of winding off the film, which has been taken up in the taking up step and which is in the state of being distorted in the wavelike manner in the rotation axis direction, from the core,
wherein in the second winding off step, the core is oscillated in the rotation axis direction and in the second winding off step, oscillation of the core is controlled so that distortion of the film which has been wound off becomes smaller.

US Pat. No. 10,427,903

LEADING EDGE DEVICE FOR A SURFACE WINDER

1. An improvement to a surface winder for winding a web material around a core having a radius, R, to obtain a log, the surface winder comprising a glue applicator for dispensing glue onto said core, a core inserter for transporting and inserting said core provided with said glue disposed thereon into a winding cradle defined at a top by an upper winding roller, supplied from above with said web material directed towards said winding cradle at a velocity, v, and at a bottom by a concave cradle associated downstream to a lower winding roller, said surface winder comprising a third oscillating roller arranged above said lower winding roller, said upper winding roller, said lower winding roller, and said third oscillating roller each having a respective axes parallel to each other and perpendicular to the feeding direction of said web material and cooperating with each other downstream of said winding cradle in order to wind said web material around said core to obtain said log, said concave cradle comprising an introductory portion, the improvement comprising:wherein said introductory portion of said concave cradle comprises a leading edge device, said leading edge device having a surface for contacting said core, said surface having a texture with protuberances provided thereto.

US Pat. No. 10,427,902

ENHANCED INTRODUCTORY PORTION FOR A SURFACE WINDER

1. A leading edge device for a surface winder, said leading edge device comprising a surface, said leading edge device having at least one channel disposed therein, said at least one channel having a single entry point and a single exit point and extending from a position external to said leading edge device and a first location disposed upon said surface, said first location disposed upon said surface being capable of receiving a fluid from said at least one channel, said fluid being fluidically displaced onto a core from said at least one channel when said core is in contacting engagement with said first location disposed upon said surface.

US Pat. No. 10,427,900

SHEET FEED APPARATUS AND IMAGE PROCESSING APPARATUS

KABUSHIKI KAISHA TOSHIBA,...

1. A sheet feed apparatus, comprising:a tray having a housing to accommodate a plurality of sheets;
a pair of first guides arranged in the tray and configured to sandwich the sheets in a direction perpendicular to a sheet conveyance direction; and
a first optical sensor provided above a bottom of the housing in at least one of the first guides, and configured to detect one or more of uppermost sheets accommodated in the housing, the first optical sensor being mounted for movement between a first position and a second position below the first position.

US Pat. No. 10,427,899

HIGH SPEED AUTOMATED FEEDING SYSTEM AND METHODS OF USING THE SAME

1. A system for separating and feeding tray-packed items individually, comprising:a. a collection station for removing a row of pre-packaged items from a package;
b. a transfer shuttle operable to grasp each end of the row and transport the row to a feeder magazine; and
c. a feeder magazine having a track for receiving the row of pre-packaged items, a driving mechanism for advancing the row of pre-packaged items through the track, and picking station operable to perform a picking operation which removes said pre-packaged items individually from said feeder magazine, comprising:
i. an arresting mechanism for preventing the advancement of the row of pre-packaged items,
ii. a stop tab operable to hold a leading pre-packaged item in said feeder magazine, and
iii. a picking mechanism operable to remove said leading pre-packaged item from said feeder magazine and deliver said leading pre-packaged item to a backend conveying system or a container,wherein said system is operable to perform said picking operation in repetition to separate said pre-packaged items and deliver them individually to said backend conveying system or said container, and said arresting mechanism is operable to arrest the advancement of said pre-packaged items during a picking operation by applying pressure to a plurality of said pre-packaged items and disengage from said plurality of said pre-packaged items between picking operations.

US Pat. No. 10,427,898

SHEET TRANSFER APPARATUS AND METHOD FOR TRANSFERRING SHEET USING THE SAME

Samsung Display Co., Ltd....

1. A sheet transfer apparatus comprising:a table on which two or more sheets, which are continuously laminated, are configured to be seated;
a sheet adsorbing part over the table to adsorb a first sheet, which is at an uppermost portion, of the two or more laminated sheets at a pressure;
an air discharge part over the table and adjacent to the sheet adsorbing part; and
an elevation unit configured to vertically elevate the sheet adsorbing part and the air discharge part,
wherein the elevation unit comprises:
a support part having a long side extending in a first direction and a short side extending in a second direction crossing the first direction; and
an elevation part configured to vertically elevate the support part,
wherein the air discharge part is configured to discharge air in a downward direction onto a surface of the first sheet adsorbed to the sheet adsorbing part.

US Pat. No. 10,427,896

IMAGE FORMING APPARATUS

Brother Kogyo Kabushiki K...

1. An image forming apparatus, comprising:an image forming unit;
a first casing that houses the image forming unit therein;
a second casing;
a document cover; and
a lock mechanism;
wherein the second casing comprises:
a document support surface located at an upper surface of the second casing; and
a positioning column protruding upward relative to the document support surface,
wherein the second casing is connected to the first casing, disposed above the first casing, and configured to pivot between a first position in which the second casing covers an upper surface of the first casing, and a second position in which the second casing reveals the upper surface of the first casing,
wherein the document cover is connected to the second casing, disposed above the second casing, and configured to pivot between a third position in which the document cover covers the document support surface, and a fourth position in which the document cover reveals the document support surface,
wherein the document cover has a positioning recess, in which the positioning column of the second casing fits when the document cover is at the third position,
wherein the lock mechanism comprises:
a fixed hook disposed at the first casing;
a movable hook disposed in the second casing;
a pressed portion configured to move in association with the movable hook; and
an actuator disposed in the positioning recess;
wherein the positioning column has a cutout portion configured to receive the pressed portion,
wherein when the second casing is at the first position and the document cover is at the fourth position, the pressed portion is located in the cutout portion and the movable hook is engaged with the fixed hook, and
wherein when the second casing is at the first position and the document cover is at the third position, the positioning column fits in the positioning recess, and the actuator contacts the pressed portion, thereby disengaging the movable hook from the fixed hook.

US Pat. No. 10,427,895

PALLET DISPENSER AND METHOD THEREOF

1. An apparatus comprising a pallet dispensing system, the apparatus comprising:a movable frame being configured to hold, at least in part, a pallet stack between a pallet-dispensation position toward a pallet-storage position, the movable frame also being configured to hold the pallet stack relative to a pallet transporter in such a way that the pallet transporter is permitted to vertically lift, at least in part, the pallet stack and the movable frame from the pallet-dispensation position toward the pallet-storage position as the movable frame is provided, at least in part, with vertical-lift assistance through stored potential energy; and
a detection assembly for detecting when the pallet transporter is moving away from the movable frame, the movable frame also being configured to automatically vertically descend from the pallet-storage position toward the pallet-dispensation position in response to the pallet transporter moving away from the movable frame.

US Pat. No. 10,427,892

MECHANISM FOR SUPPLYING MOSAIC TILE TO AN AUTOMATED TILE SETTER

CAPITAL ONE SERVICES, LLC...

11. A system for supplying mosaic tiles to an automated mosaic tile setter, the system comprising:a first pick-and-place robot configured for loading mosaic tiles into hoppers, the mosaic tiles comprising a plurality of characteristics;
a first controller operatively connected to the first pick-and-place robot and programmed to control the first pick-and-place robot to:
automatically load the mosaic tiles into the hoppers on one of a last-in, first-out basis, or a last-in, last-out basis; and
synchronize the automatic loading with an optimized ordering of the mosaic tiles, based on a desired pattern of a mosaic tile arrangement;
a second pick-and-place robot configured to pick and place the loaded mosaic tiles from the hoppers; and
a second controller operatively connected to the second pick-and-place robot and programmed to control the second pick-and-place robot to:
pick the mosaic tiles from the hoppers; and
place the mosaic tiles onto sheets of underlayment material in arrangements that form sections of the mosaic tile arrangement.

US Pat. No. 10,427,891

TRANSFER GUARD SYSTEM AND MOUNT THEREOF

Flexible Steel Lacing Com...

1. A transfer guard system comprising:an elongated mounting member for extending laterally across a gap between conveying surface portions;
at least one transfer guard member configured to be connected to the mounting member to transfer objects across the gap in a downstream longitudinal direction;
a pair of adjustable mounts configured to connect the mounting member to conveyor structure, the adjustable mounts having an installation configuration that permits adjustment of an operating position of the mounting member to a plurality of different operating positions and an operating configuration that secures the mounting member in the selected position; and
support members of each of the adjustable mounts configured to be movable between a plurality of angular orientations relative to each other and a plurality of positions relative to each other with the adjustable mount in the installation configuration and configured to be fixed relative to each other with the adjustable mount in the operating configuration.

US Pat. No. 10,427,889

TRANSMISSION EQUIPMENT

DELTA ELECTRONICS, INC., ...

1. A transmission equipment, comprising:a carrier, comprising at least one carrier guiding structure; and
a transmission rail, comprising:
a first rail, comprising a first inner rail, a first outer rail arranged in parallel to the first inner rail and at least one first transmission member disposed on the first inner rail and the first outer rail;
a second rail, comprising a second inner rail, a second outer rail arranged in parallel to the second inner rail and at least one second transmission member formed on the second inner rail and the second outer rail; and
a turning unit disposed between the first inner rail and the second inner rail, wherein a distance between the first inner rail to the turning unit is less than a distance between the first outer rail to the turning unit, and a distance between the second inner rail to the turning unit is less than a distance between the second outer rail to the turning unit, and the turning unit comprises a first guiding slot, a second guiding slot and a turning member, wherein at least one portion of the first guiding slot is parallel to the first rail, at least one portion of the second guiding slot is parallel to the second rail, the turning member moves between a first position and a second position and is disposed between the first guiding slot and the second guiding slot,
wherein in a first state, the turning member is in the first position, the carrier guiding structure enters the first guiding slot and passes over the turning member, and the carrier keeps moving in the first rail in a first direction,
wherein in a second state, the turning member is in the second position, the carrier guiding structure enters the first guiding slot and is guided by the turning member into the second guiding slot, is driven only by the first transmission member and/or the second transmission member, and the carrier then moves in the second rail in a second direction,
wherein the carrier guiding structure comprises a plurality of carrier guiding posts, and the carrier guiding posts are adapted to rotate relative to the carrier,
wherein the carrier guiding posts are disposed on two sides of the carrier, and
wherein a moving plane is defined by the first direction and the second direction, and the turning member moves parallel to a normal vector of the moving plane.

US Pat. No. 10,427,888

ON-LINE WHEEL TRANSFER MECHANISM

Citic Dicastal Co., Ltd.,...

1. An on-line wheel transfer mechanism, comprising: a first roller bed, a cylinder, a base, a linear guide rail, a rack, a guide rail seat, a first rotating shaft, first bearing seats, a gear, first rotating arms, second bearing seats, a second rotating shaft, a third rotating shaft, second rotating arms, brackets, a fourth rotating shaft and a second roller bed, wherein the cylinder, the first bearing seats and the linear guide rail are mounted on the base, the rack is connected to the linear guide rail through the guide rail seat, an output shaft of the cylinder is connected to the rack, and the first rotating shaft is mounted on two of the first bearing seats which are arranged symmetrically; the gear and two of the first rotating arms are respectively symmetrically fixed on the first rotating shaft, the rack is engaged with the gear, the second rotating shaft is mounted on two of the second bearing seats which are arranged symmetrically, two of the second rotating arms are respectively symmetrically fixed on the second rotating shaft, the first rotating arms are hinged to the brackets through the third rotating shaft, and the second rotating arms are hinged to the brackets through the fourth rotating shaft.

US Pat. No. 10,427,887

BELT BUFFER

ROTZINGER AG, Kaiseraugs...

1. A belt buffer for intermediate storage of conveyed products comprising:a plurality of buffer belts arranged in levels one above the other,
each buffer belt having a product entry side and a product exit side and consisting of a plurality of serially arranged belt modules comprising
a single tiltable entry belt module having a height-adjustable receiving edge at the product entry side and a delivery edge being level with subsequent belt modules,
a single tiltable exit belt module having a receiving edge being level with preceding belt modules and a height-adjustable delivery edge at the product exit side, and
wherein the plurality of serially arranged belt modules are horizontally arranged between the single tiltable entry belt module and the single tiltable exit belt module.

US Pat. No. 10,427,886

APPARATUS AND PROCESS FOR ROTATING PRODUCTS

1. An apparatus for rotating at least one rolled product, the apparatus comprising:a. at least one conveyor on which is conveyed at least one rolled product in a machine direction;
b. a rotator assembly moveably attached via a reciprocating linkage to a framework, the rotator assembly being driven by a first motor such that the rotator assembly cycles in a closed path in a vertical plane;
c. the rotator assembly having mounted to the linkage a second motor having a rotator cup, the framework being positioned with respect to the conveyor such that upon each cycle of the rotator assembly the rotator cup cycles close enough to the conveyor such that it can contact the rolled product throughout part of the cycle;
wherein the rotator cup comprising flanges and a distance between the flanges is adjustable.

US Pat. No. 10,427,885

ARTICLE SUPPLY METHOD AND DEVICE

Kurashiki Boseki Kabushik...

1. An article supply method using a movable block capable of a reciprocal movement between a first position and a second position, comprising:introducing one conveyed object into a housing portion formed on the movable block when the movable block is in the first position;
moving the movable block from the first position to the second position by pressurizing the movable block from a first position side of a movable area for a predetermined time to push the movable block while vacuum-sucking the movable block from a second position side of the movable area of the movable block, and then continuing the vacuum suction from the second position side;
discharging the conveyed object from the housing portion when the movable block is in the second position; and
returning the movable block from the second position to the first position by vacuum-sucking the movable block from the first position side to move the movable block to the first position.

US Pat. No. 10,427,884

VISION BASED CONVEYOR PACKAGE DENSITY MANAGEMENT SYSTEM

Fives Intralogistics Corp...

1. A method of managing bulk parcel flow with a vision management system, comprising the steps of:selecting a transition zone between a feed conveyor and a receiving conveyor each one having independent drive means;
selecting a camera field of view of the selected transition zone;
setting the feeding conveyor speed to achieve a desired conveyor area utilization on a down stream receiving conveyor according to a formula V2 (conveyor velocity of incoming items from feed conveyor)=V1 (conveyor velocity outgoing items on receiver conveyor)×2×(DO %)/(RCO %+FCO %) where V is velocity (conveyor speed), DO is Desired Occupancy, RCO is Receiving Conveyor Occupancy, and FCO is Feeding Conveyor Occupancy wherein occupancy comprises conveyor area, conveyor volume, or conveyor density);
determining a percentage of said feed conveyor occupancy defined zone;
determining a percentage of said receiving conveyor occupancy defined zone;
selecting a percentage of a desired occupancy of said receiving conveyor after a merger of said parcels from said feeding conveyor to said receiving conveyor; and
feeding said parcels from said feed conveyor at a selected rate of speed to said receiving conveyor occupancy defined zone; and
merging said parcels at said conveyor area of said transition section between said feed conveyor and said receiving conveyor.

US Pat. No. 10,427,883

MULTI-DRIVE CONVEYOR SYSTEMS AND METHODS OF USING SAME

FEDEX CORPORATION, Memph...

1. A conveyor system for advancing an item relative to a transport axis, the conveyor system comprising:a conveyor belt; and
a modular drive assembly comprising:
at least one drive module, each drive module having a housing and a pulley assembly positioned within the housing, wherein the pulley assembly of each drive module is configured to engage the conveyor belt and drive movement of the conveyor belt along a conveyor movement pathway; and
at least one take-up module, each take-up module having a housing and a pulley assembly positioned within the housing, wherein the pulley assembly of each take-up module is configured to engage the conveyor belt and provide tension to the conveyor belt as the conveyor belt moves along the conveyor movement pathway,
wherein respective positions of the housings of the at least one drive module and the at least one take-up module relative to the transport axis are selectively adjustable to modify the conveyor movement pathway.

US Pat. No. 10,427,882

CONVEYOR BELT SUPPORT SYSTEM

John Bean Technologies Co...

1. A conveyor belt support system for a conveyor having a belt movable along a frame, the conveyor belt support system comprising a plurality of support slats extending substantially along a longitudinal axis of the belt and each defining a support surface against which the belt moves, and wherein each of the plurality of support slats is moveable in at least a first direction to correspondingly move the belt in the first direction and in a second direction to correspondingly move the belt in the second direction to provide a substantially level sliding plane for the belt.

US Pat. No. 10,427,881

CONVEYOR CHAIN MODULE

1. A module for a modular conveyor chain, said module comprising:a metal link portion including a substantially elongate conveying body having opposing longitudinal sides and a bottom face;
a central hinge loop on one longitudinal side of the conveying body; and
a pair of offset hinge loops on the opposite longitudinal side of the conveying body, said pair of offset hinge loops being interspaced to receive the central hinge loop of a link portion of a consecutive module therebetween, wherein each of the hinge loops of the conveying body extend from the conveying body and loop with their free ends back towards the bottom face of the conveying body around a hinge receiving space, so that consecutive modules can be hingedly coupled by a hinge pin passing axially through aligned hinge receiving spaces of cooperating hinge loops, wherein the central hinge loop or each of the offset hinge loops of the pair of offset hinge loops define a distance between the hinge loop free end and the bottom face of the conveying body to form a through pass aperture through which a hinge pin having a diameter over at least a part of its length in the range between about 4 mm to about 8 mm held in a hinge receiving space of at least one hinge loop of another module may pass substantially transversely to its axis into or out of the hinge receiving space of the central hinge loop or each of the offset hinge loops of the pair of offset hinge loops.

US Pat. No. 10,427,880

SNAP-ON POSITION LIMITER FOR A CONVEYOR BELT

Laitram, L.L.C., Harahan...

1. A shaft for mounting components in a conveyor frame, comprising:an axial member extending from a first end to a second end;
a channel extending longitudinally along at least a portion of the axial member perimeter for receiving a tip of a conveyor component; and
a slot in an end face of the shaft for receiving a pin on a handle to selectively shift the shaft relative to the conveyor frame.

US Pat. No. 10,427,878

PATCH MATERIAL FOR REPAIRING A DAMAGED PORTION OF A PRESSING BELT

1. A patch material for repairing a damaged portion of a pressing belt used on an agricultural round baler, the patch material comprising:an operative outer polymeric layer having a first thickness, and an operative outer surface;
a mounting layer disposed parallel to the operative outer polymeric layer and configured for placement against the pressing belt, the mounting layer having a second thickness being less than the first thickness;
at least one fabric layer disposed between the operative outer polymeric layer and the mounting layer;
a plurality of delineators disposed on the operative outer surface of the operative outer polymeric layer, wherein the plurality of delineators are arranged to define a pattern having a plurality of predefined shapes;
a plurality of connecting openings extending through the operative outer polymeric layer, the at least one fabric layer, and the mounting layer;
wherein, at least one of the plurality of the predefined shapes is arranged to bound a respective one of the plurality of connecting openings.

US Pat. No. 10,427,877

CONVEYOR BELT SYSTEM

CLEAN CONVEYOR BELT BVBA,...

1. A conveyor belt system comprising a frame with a conveyor belt which is provided so as to be driven by at least two rollers so that an upper belt functions as transport surface and a lower belt functions as return, wherein the frame has an upper segment extending substantially above the upper belt and a lower segment extending substantially under the upper belt, wherein the upper segment has at least two upper standing walls with a mutual spacing which, at least at the position of the upper belt, is smaller than the width of the conveyor belt, and wherein the lower segment has at least two lower standing walls with a mutual spacing which is greater than the width of the conveyor belt, wherein the upper belt is supported on either side by a plate extending respectively from below the upper belt to an outer side of the lower standing wall, and wherein the plate has a first segment for supporting the upper belt and a second segment for discharging contaminants.

US Pat. No. 10,427,876

TIE PLATE SEPARATOR AND METHOD THEREOF

1. A tie plate sorter, comprising:a receiver having a shape which is rotatable;
a drive assembly to rotate said receiver;
a first axial end wall and a second axial end wall of said receiver and at least one side extending between said first and second axial end walls;
a plurality of magnetic retaining mechanisms positioned about said at least one side;
said magnetic retaining mechanisms selectively releasing tie plates from inside of said receiver.

US Pat. No. 10,427,874

UTILITY BAG FOR HANDLING AND MANEUVERING BULKY EQUIPMENT IN A CONFINED SPACE

1. A containment system for containing and moving an attic appliance, the containment system comprising:a cylindrical bag component configured to contain a water heater, the bag component having two ends and a long axis, wherein the bag component comprises:
a first end panel at the first end, a second end panel at the second end, and at least one wall between the first and second ends, wherein
the at least one wall is parallel to the long axis, and wherein
each of the first end panel and the second end panel are perpendicular to the long axis and connected to the at least one wall,
at the first end, a first pair of handles sewn directly into the first end panel proximate to the middle of the first end panel and a second pair of handles connected to the bag component by straps sewn to the bag component proximate to the first end panel,
at the second end, a third pair of handles sewn directly into the second end panel proximate to the middle of the second end panel and a fourth pair of handles connected to the bag component by straps sewn to the bag component proximate to the second end panel, and
a closeable opening spanning a portion of at least one of the first or second end panels and a portion of the at least one wall.

US Pat. No. 10,427,871

SCREW CONVEYOR SYSTEM FOR COMPACTION APPARATUS

1. A screw conveyor system for a compaction apparatus having a hopper receiving materials and a container storing the materials in a compacted fashion, the screw conveyor system comprising:a screw conveying the materials from the hopper to the container and including a proximal segment including flights extending in the hopper and a distal segment including flights extending in the container, the screw having a longitudinal axis; and
a passageway structure comprising a tunnel-like passage defined by at least one passageway wall, the tunnel-like passage allowing passage of the materials between the hopper and the container and being traversed by the screw, the passageway structure separating the hopper from the container, the tunnel-like passage being accessible from the hopper through an aperture having an asymmetrical shape along a cross-sectional axis extending normal to the longitudinal axis of the screw, the aperture conforming to a shape of the tunnel-like passage adjacent to the hopper, and the passageway structure comprising:
a main passageway wherein the at least one passageway wall conforms to a circumferential perimeter of the screw along a majority of the circumferential perimeter of the screw; and
a by-pass passageway extending outwardly beyond the circumferential perimeter of the screw and offset from the main passageway.

US Pat. No. 10,427,870

WASTE RECEPTACLE HOLDING DEVICE

1. A holding device, comprising:a handle having a handle first end and a handle second end;
a circular lower hoop secured to said handle second end;
a circular upper hoop having a larger diameter than said lower hoop and secured to said handle second end adjacent said lower hoop with a hinge;
an upper hoop retention clip secured to said handle adjacent said hinge; and,
a waste bag retention clip secured to said upper hoop opposite said hinge;
a rake threadingly secured over said handle first end;
wherein a waste receptacle is adaptably removably secured in an open configuration to said device when positioned between said lower hoop and said upper hoop and when said waste bag retention clip removably secures said lower hoop against said upper hoop;
wherein said waste bag retention clip further comprises an aperture configured to permit said device to be suspended;
wherein said rake comprises:
a handle;
a ferrule disposed adjacent said handle; and,
a plurality of tines disposed adjacent said ferrule opposite said handle;
wherein said lower hoop is made of stainless steel; and
wherein said upper hoop is made of stainless steel.

US Pat. No. 10,427,869

BAG RECEPTACLE HOLDER APPARATUS

1. A tool for picking up and depositing animal waste in a plastic disposable bag, comprising:a. a cylindrical sleeve with a top opening, a bottom opening, a sidewall and a side hole formed on said sidewall;
b. a holder used to temporarily hold a plastic bag inside said cylindrical sleeve, said holder includes a bolt with a head, and a threaded shaft, said head being located inside said cylindrical sleeve and said shaft being extended through said side hole formed on said sidewall;
c. a lock washer that attaches to said shaft to hold said shaft inside said side hole; and
d. a flange nut with internal threads that selectively attaches to said threaded shaft, said flange nut includes an inside surface that presses against said sidewall of said cylindrical sleeve when said flange nut is tighten on said threaded shaft, when said bag is extended into said top opening of said cylindrical sleeve and a top portion of said bag is extended over said sidewall and adjacent to said side hole, said flange nut is forced against said top portion of said bag extending over said sidewall to securely hold said bag on said cylindrical sleeve.

US Pat. No. 10,427,867

PACKING MEMBER AND CARTRIDGE PACKED IN THE PACKING MEMBER

Canon Kabushiki Kaisha, ...

1. A packing member for packing a cartridge, the cartridge including a photosensitive drum on which an electrostatic latent image is to be formed and the cartridge being detachably mountable to an image forming apparatus, wherein the packing member is molded with a resin material, the packing member comprising:(i) a first portion including (a) an opening as an entrance for the cartridge, (b) a recessed portion for accommodating the cartridge, (c) a first limiting portion for limiting a position of the cartridge in a first direction perpendicular to an axial direction of the photosensitive drum, and (d) a second limiting portion for limiting a position of the cartridge in a second direction perpendicular to the axial direction of the photosensitive drum and crossing to the first direction; and
(ii) a second portion for openably covering the opening,
wherein the first limiting portion and the second limiting portion contact portions of the cartridge excluding a region where the electrostatic latent image is to be formed on the photosensitive drum such that a gap is formed between a surface of the photosensitive drum and an inner surface of the recessed portion.

US Pat. No. 10,427,866

ADULT TOY CONCEALING CONTAINER

5. A container with the appearance of a shampoo bottle, a conditioner bottle, or a soap dispenser, for concealing an adult toy so that the adult toy within the container can be inconspicuously transported and stored around the living environment comprising:a bottom portion, a main compartment and a top portion;
the bottom portion comprising an upper part and an underside with an attachment around the outside edge of the upper part;
the upper part of the bottom portion further comprising a stand to hold the adult toy within the container;
the main compartment comprising an upper edge, a lower edge and a plurality of sides wherein the plurality of sides come together to form a closed geometric shape or other artistic shape in order to appear as the personal hygiene item, and is hollow so that the adult toy can be concealed within the main compartment;
the lower edge of the main compartment further comprising a receiver to allow the main compartment to be attached to the bottom portion;
the upper edge of the main compartment further comprising a receiver;
the bottom portion further comprising a storage compartment wherein the upper part is attached to the storage compartment by an appropriate attachment, is removable from the storage compartment portion and the storage compartment can be filled with a plurality of disposable wipes;
the upper part of the bottom portion further comprising an opening such that the plurality of disposable wipes can be removed from the storage means one at a time;
the top portion comprising a lower edge and an opening apparatus;
the top portion further comprising a hollow compartment within the top portion to allow the top portion to hold a liquid and having the appearance of the container as a personal hygiene item;
the opening apparatus is at least one of a flip top with additional opening or a pump means to allow the user of the container to extract liquid within the hollow compartment; and
the lower edge of the top portion comprising an attachment to allow the top portion to be attached to the main compartment.

US Pat. No. 10,427,865

RESEALABLE INNER PACKAGE FOR A CONTAINER

Philip Morris Products S....

1. A container for consumer goods, comprising:a housing comprising a box and a lid, wherein the box and the lid each comprise a front wall and a back wall;
a hinged connector that connects the lid to the back wall of the box, wherein the hinged connector is connected to the lid at a first hinge line and connected to the back wall of the box at a second hinge line;
an inner package disposed within the housing and at least partially defining an interior volume for housing consumer goods, wherein the inner package comprises a front wall, a back wall, and a top wall, wherein the inner package further comprises:
a first layer that defines a flap; and
a second layer at least partially attached to an inner surface of the first layer that defines an access opening through which the consumer goods can be removed, wherein the access opening is disposed in a portion of the back and top walls of the inner package;
wherein the lid is movable between a closed position and an open position, wherein the inner package is covered by the lid and the box when the lid is in the closed position and at least partially uncovered when the lid is in the open position;
wherein the flap is attached to an inner surface of the front wall of the lid such that the flap is separated from the inner package to at least partially uncover the access opening when the lid is moved from the closed position to the open position, and further wherein the flap covers the access opening when the lid is in the closed position.

US Pat. No. 10,427,864

RIGID PACK WITH HINGED LID AND INTERNALLY PROVIDED WITH A COLLAR HAVING AN UPPER WALL

1. A rigid pack (1) for tobacco articles comprising:a container (2), which has a parallelepiped shape, has an open upper end, a container lower wall (5), a container front wall (6), a container rear wall (7), and two container lateral walls (8);
a lid (3) which is hinged to the container (2), has a parallelepiped shape and has a lid upper wall (9), a lid front wall (10), a lid rear wall (11), and two lid lateral walls (12);
an inner wrap (4) which encloses a group of tobacco articles, and is housed on the inside of the container (2); and
a collar (13), which embraces the inner wrap (4), is internally glued to the container (2), and protrudes from the open upper end of the container (2) and has: a collar front wall (14), two collar lateral walls (15) and a collar upper wall (16) which is perpendicular to the collar front wall (14); and
wherein the collar (13) has a pull-out opening (18) for the tobacco articles which involves a portion of the collar front wall (14) and a portion of the collar upper wall (16); and
wherein the collar upper wall (16) comprises a fixed frame which is “U”-shaped and surrounds an upper part of the pull-out opening (18) on three different sides.

US Pat. No. 10,427,863

AEROSOL CONTAINER, AND DETAILS THEREOF

1. A stabilizing member forming an upper valve housing for an aerosol valve having a valve stem for operating said valve, said stabilizing member comprising a body having a resilient portion arranged at a periphery of said stabilizing member for snap fitting in a groove formed on an inside of an associated hollow body, and a radial projection arranged at the periphery of the stabilizing member and axially displaced relative the resilient portion, wherein the radial projection is configured to seal against an inner wall of the associated hollow body, and wherein the radial projection is formed by a resilient material.

US Pat. No. 10,427,862

AEROSOL DISPENSER ASSEMBLY HAVING VOC-FREE PROPELLANT AND DISPENSING MECHANISM THEREFOR

1. An aerosol dispenser system having a volatile organic compound (VOC)-free propellant comprising:an enclosed container accommodating a liquid product under pressure;
a valve assembly coupled to and in fluid communication with the container;
an actuator body coupled to and in fluid communication with the valve assembly; and
at least one swirl nozzle insert coupled to and in fluid communication with the actuator body, the at least one swirl nozzle insert comprising a cylindrical sidewall connected to an end wall, the cylindrical sidewall having a diameter D less than 4,000 ?m defining an open bottom, the end wall comprising a recess that defines a swirl chamber, the end wall further comprising an outlet orifice connected to the swirl chamber and the end wall further comprising at least one inlet slot extending inward from a junction of the cylindrical sidewall and end wall towards the swirl chamber,
the outlet orifice having a diameter do and an axial length Lo, the axial length Lo being less than 250 ?m, the swirl chamber having a diameter Ds, the inlet slot comprising a width dp, a height Ls, and a cross-sectional area dp×Ls defined by said width dp and height Ls, a number of inlet slots N ranging from 1 to 6,
do, Ds and a cumulative cross-sectional area of the N slots, dp×Ls×N, being used to achieve a Sauter Mean Diameter D[3,2] of particles exiting the outlet orifice below a predetermined upper limit when the aerosol dispensing system is charged with an aqueous product.

US Pat. No. 10,427,860

PACKAGING

1. A packaging comprising a pouch intended to contain a product and to allow release thereof, comprising:a manually deformable jacket formed of a first film that collapses under its own weight, the first film comprising a first inner side and a first outer side, the first film being closed on itself so as to form a frustum having a first and second end, the cross section of the frustum narrowing as the first end is approached, the inner side forming the interior of the frustum and the outer side forming the exterior of the frustum;
a base formed of a second film that collapses under its own weight, the second film comprising a second inner side and a second outer side and the second film being sealed at the second end of the frustum so as to close off the second end, the base and the jacket are thermally sealed first inner side to second inner side in order to form together a manually deformable pouch, the first and second inner side being configured to be in contact with the product;
a closure device through which the product flows when the pouch is manually deformed and comprising a sleeve sealed to the first end of the frustum,
wherein
the base has a diamond shape including a first, a second, a third, and a fourth angle, the first angle being equal to the third angle and opposite to the third angle, the second angle being equal to the fourth angle and opposite to the fourth angle, the first angle being different from the second angle.

US Pat. No. 10,427,859

DISPENSER FOR A CREAM, GEL OR SOFT SOLID COMPOSITION

Conopco, Inc., Englewood...

1. A dispenser suitable for delivery of a cream, gel or soft solid composition comprising:(i) a convex applicator surface at an upper end;
(ii) a replaceable cartridge containing a composition to be dispensed;
(iii) a passageway between the cartridge and the applicator surface;
(iv) a drive mechanism for forcing the composition from the cartridge through the passageway and onto the applicator surface;
(v) an outer body containing features (ii) to (iv); and
(vi) a non-return ratchet which interacts with a plunger to prevent significant axially movement of the plunger whilst a dial unit is rotated in a second direction;the drive mechanism comprising the dial unit and the plunger, rotation of the dial unit in a first direction advancing the plunger axially upwards, the plunger acting upon a piston seal at the base of the replaceable cartridge, thereby forcing the contained composition upwards and outwards through the passageway and onto the applicator surface; rotation of the dial unit in the second direction, counter to the first, rotationally re-setting the dial unit relative to the plunger in readiness for a further advancement of the plunger, rotation in the second direction not causing significant axial movement of the plunger and being brought about by a torsion spring that forces the dial unit back to its position before the dial unit was turned when torque applied to turn the dial unit in its first direction is released, wherein an advancing ratchet which is rotationally locked to the dial unit interacts with advancing teeth on the plunger to cause the plunger to be raised axially upwards when the dial unit is rotated in its first direction and wherein the non-return ratchet is rotationally locked to the dial unit and interacts with a set of non-return teeth on the plunger to prevent axially downward movement of the plunger when the dial unit is rotated in its second direction and wherein the advancing ratchet and the non-return ratchet are part of a ratchet sleeve, which is moulded independently of the dial unit, but slotted in to the dial unit in a rotationally fixed manner during assembly of the dispenser.

US Pat. No. 10,427,858

INSULATED BOTTLE HOLDER

1. A bottle holder device for containing a beverage bottle having a neck defining an opening through which contents of the bottle are poured by a user, said bottle holder device inhibiting temperature change during a period of time in which said contents are consumed, said bottle holder comprising:a body having a base portion and a generally cylindrical portion for receipt of said bottle;
said body configured to have thermal insulator characteristics which inhibit temperature change of said bottle;
a lid having a lower portion adapted to removably engage said body and an upper portion, said body and said lid together defining an interior cavity for containing said bottle;
said lid defining an aperture through which said neck of said bottle will extend to allow said contents of said bottle to be poured; and
a seal carried by said lid and being formed of compressible material, said seal having an attachment portion attached to said lid and a flexible web portion connecting said attachment portion and an engaging portion, said engaging portion being widened so as to contact said neck of said bottle adjacent said aperture to accommodate and maintain different sizes of said bottle;
wherein said attachment portion, said web portion, and said engaging portion of said seal form a generally U-shaped configuration with said web portion being at the bottom of said U-shaped configuration and thereby providing an air gap between said attachment portion and said engaging portion, said web portion of said seal being spaced apart from an inner surface of said lid toward said base portion of said body such that said engaging portion may deflect into the air gap as said neck is received through the aperture of the lid to accommodate said bottle, an upper portion of said engaging portion of said seal being curved outward.

US Pat. No. 10,427,856

METHOD OF CREATING AND MAINTAINING A VACUUM IN A STORAGE BAG

4. A method of creating and maintaining a vacuum in a bag comprising thesteps of: securing a bag, the bag having two walls, the walls of the bag having an internal wall inside the bag, a polymeric film material makes up the walls of the bag, an inert, compressible, resilient, expanded open-cell polymeric sponge material is an integral part of an internal wall of the bag, its size determined by the dimensions of the bag's internal wall, an
airtight sealable end of the bag that will stop migration of gases in or out
of the bag, and a one-way valve through one wall of the bag:
placing an article to be stored into the bag;
compressing the inert, compressible, resilient, expanded open-cell polymeric sponge material that is an integral part of an internal wall of the bag;
closing the airtight, sealable end of the bag to stop migration of gases in or out of the bag; and releasing compression of the sponge material when the bag is sealed, thereby creating and maintaining a vacuum inside of the bag.

US Pat. No. 10,427,855

INFLATABLE PACKAGING

Owen Townsend Barnitz, S...

1. A system for packaging an item, the system comprising:a plurality of inflatable units, wherein a respective inflatable unit is located at a respective corner of a plurality of corners of the item;
a plurality of straps securing the inflatable units to the corners of the item; and
a beam extending between two of the inflatable units that support the item, such that a first end of the beam is located in a recess of a first one of the inflatable units and a second end of the beam is located in a recess of a second one of the inflatable units.

US Pat. No. 10,427,852

FLEXIBLE FITMENT FOR FLEXIBLE CONTAINER

Dow Global Technologies L...

1. A flexible container comprising:a first multilayer film and a second multilayer film, each multilayer film comprising a seal layer, the multilayer films arranged such that seal layers oppose each other and the second multilayer film is superimposed on the first multilayer film, the films sealed along a common peripheral edge;
a fitment comprising a base, the base comprising an ethylene/?-olefin multi-block copolymer consisting of an ethylene monomer and a C3-C20 ?-olefin comonomer, the ethylene/?-olefin multi-block copolymer having an elastic recovery from 50% to 90% as measured in accordance with ASTM D 1708 (300% min?1 deformation rate at 21° C.); and
a fitment seal comprising the base located between the multilayer films and the base is sealed to each multilayer film at a portion of the common peripheral edge.

US Pat. No. 10,427,850

QUICK-ADJUST TENSIONER

Akerworks, Inc., Knoxvil...

1. A tensioner, comprising:a stop, a first member, and a foot;
said stop includes a first aperture, wherein at least a portion of said stop that defines said first aperture comprises a resilient material;
said first member connects said stop to said foot, said first member is resilient, said first member is configured to bias to a straight position;
said foot includes a second aperture, said second aperture is circular, wherein any diameter of said second aperture is greater than the smallest diameter of said first aperture, said first and second apertures are parallel when said first member is in said straight position;
wherein a first side of said stop, a first side of said first member, and a first side of said foot are contiguous and defined by a first plane when said first member is straight;
wherein a second side of said stop, a second side of said first member, and a second side of said foot are contiguous, said second side of said first member is defined by a second plane when said first member is straight;
wherein a third side of said stop, a third side of said first member, and a third side of said foot are contiguous, said third side of said first member is defined by a third plane when said first member is straight;
wherein said stop is thicker than said foot such that a height of said first aperture is greater than a height of said second aperture;
wherein said first member is capable of bending such that said first aperture aligns completely superposed in said second aperture;
wherein said first member is capable of bending such that said stop contacts said foot such that said first and second apertures are coaxial while said first member maintains full resilience to bias return to said straight position.

US Pat. No. 10,427,849

CABLE TIE ADAPTER

Advanced Cable Ties, Inc....

1. A unitary molded plastic one-piece cable tie adapter, comprising:unitary front and rear portions that are parts of a single structure:
a front, and an opposing rear edge:
an upper surface that is contiguous from the front to the rear edge: wherein the front portion comprises: a front portion bottom;
a securing slot that extends from the contiguous upper surface to the front portion bottom; and a movable pawl in the securing slot; andwherein the rear portion comprises:a rear portion bottom;
a cavity that is spaced from the securing slot and that is open to the contiguous upper surface;
an elongated slot extending from the cavity to the rear edge, the elongated slot having an open top that is open to the contiguous surface; and a fixed securing mechanism located on the contiguous upper surface and extending across part of the elongated slot, to partially cover the open top of the elongated slot; and
wherein the adapter is configured such that a cable tie with a head and a strap can be installed in the adapter by placement of the cable tie head in the rear portion cavity with the cable tie strap extending through the entire length of the elongated slot in the rear portion and extending through the securing slot and engaged with the movable pawl in the front portion.

US Pat. No. 10,427,848

INSULATING PACKAGE METHOD

Knauf Insulation SPRL, V...

1. A method of introducing mineral fiber blowing wool from a package of compressed mineral wool insulation loose blowing wool fibers into a blowing machine comprising:compressing uncompressed mineral wool insulation blowing wool fiber with a press along a single axis to produce a compressed bulk of blowing wool fibers;
retaining the compressed bulk of blowing wool fibers with at least one retainer to form the package,
removing the at least one retainer from the package and removing any enveloping film covering an upper surface of the blowing wool package; and
displacing mineral wool fibers from the upper surface of the package to an inlet of a blowing machine.

US Pat. No. 10,427,847

CONTAINER WITH A CHILD-PROOF LOCK

SANNER GMBH, Bensheim (D...

1. A container comprising:a container body having a container opening;
a container closure for the container opening, said closure being movable from a closed to an open position; and
a removable tamper-proof element,
wherein the container closure comprises a child safety device having an actuating element wherein the tamper-proof element blocks movement of at least a portion of the actuating element and wherein after the tamper-proof element is removed, at least a portion of the actuating element is movable from a first position, in which the container closure is secured, to a second position, in which the container closure is not secured,
wherein the actuating element has a sliding body that can be moved from the first to the second position, and wherein the sliding body has a window wherein the tamper-proof element is arranged in the window.

US Pat. No. 10,427,846

SYSTEM AND METHOD FOR DETERMINING PACKAGE TAMPERING

Walmart Apollo, LLC, Ben...

1. A tape dispensing system, the system comprising:packaging tape including a first portion and a second portion;
an application apparatus that is configured to apply the packaging tape to a first package and a second package;
an incision element that is configured at a first time to define a first unique pattern and that is configured at a second time to define a second unique pattern, the incision element being connected to the application apparatus, wherein the incision element comprises multiple prongs and a number of the prongs and a height of each of the prongs are varied to obtain the first unique pattern at the first time and are readjusted at the second time to obtain the second unique pattern;
such that a movement of the application apparatus is effective to punch or incise the first unique pattern defined by the incision element completely through the first portion of the packaging tape and into the first package as indentations as or after the first portion of the packaging tape is applied to the first package at the first time;
such that a movement of the application apparatus is effective to punch or incise the second unique pattern defined by the incision element completely through the second portion of the packaging tape and into the second package as indentations as or after the second portion of the packaging tape is applied to the second package at the second time;
wherein a first incised pattern is formed through the first portion of the tape, and a second incised pattern is formed in the first package, and wherein a first inspection is performed to determine if the first incised pattern through the first portion of the tape aligns with the second incised pattern in the first package;
wherein a third incised pattern is formed through the second portion of the tape, and a fourth incised pattern is formed in the second package, and wherein a second inspection is performed to determine if the third incised pattern through the second portion of the tape aligns with the fourth incised pattern in the second package;
wherein the indentations in the first package are filled with ink to facilitate the first inspection and the indentations in the second package are filled with ink to facilitate the second inspection.

US Pat. No. 10,427,845

TAMPER EVIDENT CLOSURE

Obrist Closures Switzerla...

1. A closure comprising:a body portion having engagement means for engagement with a container to prevent removal of the body portion from the container, wherein the engagement means comprises at least one clip for securing the body portion to a neck of the container, and wherein the body portion is made from plastic, and
a shell for engagement with the body portion, wherein the shell comprises securing means arranged in use to secure the engagement means onto the container, and wherein the securing means is a bead, wherein the shell is made from metal;
wherein the bead secures the at least one clip to the container so that the body portion cannot be removed from the container after the closure has been applied to the container.

US Pat. No. 10,427,844

CONTAINER LID

1. A lid for a bucket, said lid comprising:a side wall extending upward from a collar along a circular lower edge and forming a dome;
said collar selectively securing said lid to said bucket, said bucket being formed of paper or corrugated material and having a lip with a thickness along a circumference of a top portion of said bucket, where said collar has a plurality of horizontal detents shaped as trapezoids that project inward toward a central axis of said collar and to a greater extent than the circular lower edge to latch onto a bottom portion of said lip when said lip is within a specified thickness, each of said plurality of horizontal detents vertically offset above the circular lower edge of said collar and each of said plurality of horizontal detents having a lower width proximal to the circular lower edge that is less than an upper width proximal to said side wall, each of said plurality of horizontal detents separated by at least one of a plurality of outwardly extending ribs and a region lacking a horizontal detent, each of said plurality of outwardly extending ribs being orthogonal to said detents; and
a flexible and expandable under hang disposed below said plurality of detents, said flexible and expandable under hang having a diameter, said under hang having an circumferential indentation with an inward spring force that grabs said lip of said bucket when said lip is greater than the specified thickness and when said lip is less than the diameter such that said plurality of horizontal detents latch onto a bottom portion of said lip and able to compensate for a variation in the circumference of said bucket;
wherein each of said plurality of outwardly extending ribs extends from between said plurality of horizontal detents into said flexible and expandable under hang.

US Pat. No. 10,427,843

LIQUID DISPENSING SPOUT ASSEMBLY

TPG Plastics LLC, Willow...

1. A liquid dispensing spout assembly, comprising:a housing having a first cylindrical portion and a second cylindrical portion attached at an angle to the first cylindrical portion;
a spout attached to the second cylindrical portion; and
a valve assembly, the valve assembly including a valve shaft disposed inside the first cylindrical portion and a trigger mechanism atop the valve shaft, the trigger mechanism including a dual acting cap having a flexible portion with a tab disposed thereon, and requiring the two-step process of pressing the flexible portion toward the valve shaft until the tab clears a top of a first end of the first cylindrical portion and pushing on the dual acting cap to position the tab inside the first cylindrical portion to actuate the valve assembly, wherein actuation of the valve assembly is required for dispensing liquid through the spout.

US Pat. No. 10,427,840

PRESS IN FLANGE CONTAINER CLOSURE SYSTEM

GREIF INTERNATIONAL HOLDI...

17. A method of snap-fittingly installing an insert in an aperture in a container wall,the insert comprising an external circumferential groove; an internally threaded, through-going opening adapted to receive a complementary, externally threaded plug to form a fluid-tight sealed closure; and an end forming a tapered rim which, prior to installation of the insert in the container aperture, provides:
(i) a guide surface and
(ii) a rearwardly facing shoulder;
an edge portion of the container aperture being formed as an upstanding collar;
the method comprising the steps of:
installing a sealing element in the circumferential groove;
pressing the insert into the collar so that the guide surface resiliently deforms the insert and/or the collar and the sealing element is carried into the collar under reduced or no compression, and further pressing the insert into the collar so as to allow a forward end of the collar to snap fit into place behind the rearwardly facing shoulder;
the insert and/or the collar thereby resiliently recovering so as to compress the sealing element between the circumferential groove and the upstanding collar.

US Pat. No. 10,427,839

RESEALABLE BAG

BAGEM PACKAGING SERVICES ...

1. An improved resealable bag of the type having:a pair of walls, each defining a side of the bag, the walls being joined to one another to define a pair of spaced apart side edges of the bag between which side edges of the walls each extend,
a bottom from which the walls extend and an upper edge to which the walls extend;
for each of the walls and operatively secured thereto, proximal to and spaced from the upper edge, a component, the components mating with one another to define a recloseable press-to-seal fastener,
the improvement comprising:
for each side of the bag, a flap disposed intermediate the recloseable fastener and the bottom; and
said flap defining an opening for receiving a first finger of a one hand, a bottom of said opening being located adjacent said recloseable press-to-seal fastener and the flap being sized and dimensioned such that the flap lies flush against the side of the bag except when stretched or drawn apart therefrom;
each side of the bag defining a finger pressure receiving region spaced from and located outside said flap and adjacent said recloseable fastener such that said first finger and a second finger of the one hand and a first and a second finger of another hand can be used to concurrently grip said sides of said bag such that said bag is gripped with both hands and said fingers cooperate to apply a pivotally directed opening force to said recloseable press-to-seal fastener in order to effect release of said recloseable press-to-seal fastener.

US Pat. No. 10,427,835

CONTAINER WITH INTERCHANGEABLE CRYSTAL DISPLAYS

1. A container with an interchangeable crystal display, the container comprising:a container body sized to accommodate a volume of a liquid, the container body having an upper end and a lower end;
a cap designed to removably engage with the upper end of the container body;
a container base designed to removably engage with the lower end of the container body; and
an interchangeable crystal display removably secured to a surface of the container base such that the interchangeable crystal display extends upwards from the container base into an interior of the container body when the container base is engaged with the lower end of the container body,
wherein the interchangeable crystal display further comprises a crystal removably secured to a crystal base, wherein the crystal base is designed to secure to the container base,
wherein at least one channel extends through a portion of the crystal proximate to the crystal base; and the channel has a diameter sufficient to accommodate a wire being threaded therethrough.

US Pat. No. 10,427,834

STRUCTURAL ELEMENT

Gridesic Holdings Limited...

1. A structural element in the form of a structural panel, the structural element comprising:two outer sheets that act as the tensile and compression chords, with the two outer sheets comprising multiple inwardly orientated pods throughout the structural panel, the inwardly orientated pods having apexes that are joined together, which pods have a close proximity to one another in order to be mechanically interdependent creating a double depth space-frame lattice type matrix where loads placed on a surface of the structural panel are resisted and transferred through the chords and with the inwardly orientated pods acting as interconnecting diagonal braces such that the loads are transmitted along the surfaces of the pods in multiple directions and distributed throughout the structural element,
wherein walls of a side cross-section of joined pods form diamond beam formations with adjacent joined pods such that multiple diamond beam structures are formed in the structural element in the negative spaces immediately between pairs of joined pods,
wherein the walls of the side cross-section of each of the inwardly orientated pods comprise straight sides,
wherein the pods are frusto-conical in shape, and
wherein mouths of the pods are round and arranged in rows, adjacent rows being staggered to define a grid with centerlines for the pods at 120° from one another, and the pods being spaced apart between 1 and 11% of the pod diameter.

US Pat. No. 10,427,833

ASSEMBLABLE PALLET

AIR-BAG PACKING CO., LTD....

1. A pallet, comprising:a plurality of first base members, each of the first base members comprising a first base body, a plurality of first fixing grooves formed on the first base body, and a first angled fixing groove formed on the first base body, wherein the first fixing grooves of each of the first base members are in communication with each other, the first fixing grooves of each of the first base members are oriented orthogonally, and one end of the first angled fixing groove intersects with one end of each of the first fixing grooves;
a plurality of second base members, each of the second base members located between the corresponding two first base members, wherein each of the second base members comprises a second base body, a second fixing groove formed on the second base body, and a second slot formed on the second base body, wherein one end of the second fixing groove is in communication with the second slot, and the second fixing groove and the second slot of each of the second base members are oriented orthogonally;
a central base member, located between the second base members, wherein the central base member comprises a central base body, a plurality of central slots formed on the central base body, and a plurality of central angled slots formed on the central base body, wherein the central slots are intersected at an intersecting point of the central base body, and the central slots and the central angled slots cross at an intersecting point of the central base body;
a plurality of connecting bars, fixedly received in the first fixing grooves, the second fixing grooves, the second slots, and the central slots to secure the central base member, the first base members, and the second base members to form a pallet frame, wherein two ends of each of the connecting bars are abutted against respective inner walls of the first fixing grooves or respective inner walls of the second fixing grooves, so that the connecting bars are positionally restricted by the first fixing grooves, the second fixing grooves, and the central slots;
a plurality of slanted connecting bars, fixedly received in the first angled fixing grooves and the central angled slots to secure the central base member and the first base members, wherein the slanted connecting bars are positionally restricted by the first angled fixing grooves and the central angled slots; and
a loading plate, fixed on the pallet frame.

US Pat. No. 10,427,832

RESEALABLE CONTAINER LID ASSEMBLY AND ACCESSORIES INCLUDING METHODS OF MANUFACTURE AND USE

1. A container lid comprising:a vertical sidewall having a cylindrical shape extending between an upper peripheral edge and a lower peripheral edge,
a seaming panel concentrically formed annularly and extending upward and radially outward from the vertical sidewall upper peripheral edge, the seaming panel being adapted to assemble the container lid to a container body comprising a cylindrical sidewall extending upward from a container body closed bottom wall;
a container lid rotational and axial guide feature integral with the vertical sidewall, the container lid rotational and axial guide feature extending radially from an interior surface of the vertical sidewall, and
a seaming chuck shoulder formed between the seaming panel and the container lid rotational and axial guide feature, wherein the seaming chuck shoulder is formed as a transition extending inward and downward between the seaming panel and the vertical sidewall.

US Pat. No. 10,427,830

ROTATING SIDEWALL STOP FOR SUPPORTING FOLDING SIDEWALLS OF A HEIGHT-EXTENDED BULK BOX

Schaefer Systems Internat...

1. A height-extended bulk box, comprising:(a) a quadrilateral base;
(b) four height-extending walls connected to respective sides of the base;
(c) four sidewalls pivotally mounted to respective ones of the height-extending walls and movable between a vertically erected use position and a collapsed configuration wherein the sidewalls are rotated inwardly into the area defined by quadrilateral base; and
(d) at least one sidewall stop positioned on one of the height-extending walls and movable between a non-use stowed position and a deployed position that extends into the volume of the bulk box and arrests movement of a first of the sidewalls to be moved into a collapsed position past a position substantially parallel to the top deck of the base.

US Pat. No. 10,427,829

THINNED METAL CAN END

Silgan Containers LLC, W...

1. A metal, multi-thickness, one-piece can end formed from a single sheet of metal, having a first surface and a second surface, the end comprising:a circular panel formed at the center of the sheet of metal, a distance perpendicular to and between the first surface and the second surface at the central panel defining a panel material thickness;
an annular ridged portion formed at a portion of the sheet of metal extending from and surrounding the circular panel; and
an annular outside formation formed at a portion of the sheet of metal extending from and surrounding the annular ridged portion, a distance perpendicular to and between the first surface and the second surface at the annular outside formation defining an outside formation material thickness, the outside formation material thickness being at least 1.15 times as thick as the panel material thickness, wherein the annular formation is used to join the end to a can body with a double seam.

US Pat. No. 10,427,828

CORRUGATED PAPERBOARD BOX, PERFORATION FORMING METHOD FOR PERFORATING CORRUGATED PAPERBOARD SHEET, AND PERFORATION FORMING DEVICE AND PERFORATION FORMING UNIT FOR PERFORATING CORRUGATED PAPERBOARD SHEET

RENGO CO., LTD., Osaka (...

1. A corrugated paperboard box comprising:corrugated paperboard including:
an outer linerboard,
an inner linerboard, and
a corrugated medium provided between the outer linerboard and the inner linerboard,
wherein the corrugated paperboard box has:
a peripheral wall formed by bending the corrugated paperboard into a tubular shape such that the inner linerboard constitutes an inner surface of the corrugated paperboard box; and
flaps integrally connected to one of two ends of the peripheral wall,
wherein the corrugated paperboard box has a boundary area between the peripheral wall and the flaps, a groove-shaped reverse scoreline recessed on a side of the outer linerboard at the boundary area, and a pair of groove-shaped recesses recessed on a side of the inner linerboard at the boundary area, the pair of groove-shaped recesses extending in parallel to each other so as to sandwich a reverse scoreline area in which the reverse scoreline extends,
wherein the corrugated paperboard box has a perforated line in one of the pair of groove-shaped recesses, the perforated line configured to allow the flaps to be separated from the peripheral wall, and the perforated line comprising a plurality of cuts penetrating through the inner linerboard, the corrugated medium, and the outer linerboard,
wherein the corrugated paperboard is configured to allow the flaps to be bent along the perforated line toward an inner surface of the peripheral wall,
wherein each of the cuts of the perforated line has a first cut portion formed in the outer linerboard, and a second cut portion formed in the inner linerboard, and
wherein the perforated line is formed such that a width of each of the first cut portions in an orthogonal direction relative to a direction in which the perforated line extends is smaller than a width of each of the second cut portions in the orthogonal direction.

US Pat. No. 10,427,827

BOX WITH IMPROVED GRIPPING FUNCTIONALITY

1. A box, comprising:at least four side panels, including:
a first minor panel foldably coupled to a first minor flap;
a first major panel foldably coupled to a first major flap;
a second minor panel foldably coupled to a second minor flap;
a second major panel foldably coupled to a second major flap;
a top end; and
a bottom end,
wherein the top end includes the first and second minor flaps and the first and second major flaps, with the first minor flap positioned opposite the second minor flap, and the first major flap positioned opposite the second major flap,
wherein portions of the first and second major flaps overlie portions of the first and second minor flaps,
wherein an opening extends through portions of the first and second major flaps between the first and second minor flaps, and
wherein the opening extends an entire distance between opposing peripheral edges of the first and second major panels.

US Pat. No. 10,427,826

REUSABLE JUG

1. A device, which is comprised of:a. a jug;
wherein the jug has a top opening and a bottom opening;
wherein a set of female threads are provided on the bottom opening of the jug;
wherein a set of male threads are provided on the top opening of the jug;
b. a top cap;
wherein the top cap provides female threads;
wherein the top cap threads over the male threads of the top opening of the jug;
c. a large bottom cap;
wherein the large bottom cap provides a set of male threads;
wherein the large bottom cap provides a first set of female threads;
wherein the large bottom cap provides a second set of female threads;
wherein the large bottom cap threads into the bottom opening of the jug;
wherein the large bottom cap has an opening;
wherein the first set of female threads are provided within the opening;
d. a small bottom cap;
wherein the small bottom cap has a set of male threads;
wherein the male threads of the small bottom cap thread into the first set of female threads of the large bottom cap;
e. an internal receptacle;
wherein the internal receptacle has male threads;
wherein the internal receptacle threads into the second set of female threads of the large bottom cap;
f. a first seal;
wherein the first seal is provided between the large bottom cap and the bottom opening of the jug;
g. a second seal;
wherein the second seal is provided between the large bottom cap and the internal receptacle.

US Pat. No. 10,427,825

PORTABLE CANTEEN WITH STORAGE COMPARTMENTS

1. A canteen for removably concealing at least one article within a bottom cavity of the canteen, wherein the canteen comprises:a main body; wherein the main body comprises:
an exterior surface that is substantially opaque exteriorly hiding the bottom cavity;
a top cavity and the bottom cavity both of which are formed from the main body;
wherein the top cavity and the bottom cavity are longitudinally disposed of each other in a manner that a bottom portion of the top cavity is disposed above a roof portion of the bottom cavity;
wherein a volume of the top cavity is bound by a top interior surface of the top cavity that runs from a top opening of the top cavity to the bottom portion of the top cavity, wherein the top opening of the top cavity is disposed above the bottom portion of the top cavity; wherein a volume of the bottom cavity is bound by a bottom interior surface of the bottom cavity that runs from a bottom opening of the bottom cavity to the roof portion of the bottom cavity, wherein the bottom opening of the bottom cavity is disposed beneath the roof portion of the bottom cavity; wherein less than a majority of the volume of the bottom cavity extends into the volume of the top cavity in a manner that is radially symmetrical about a shared central longitudinal axis of both the top cavity and the bottom cavity; and
a bottom lid, wherein the bottom lid is of a fixed length, wherein the bottom lid is closed at an end distal from the roof portion of the bottom cavity, wherein the bottom lid is substantially hollow, wherein the bottom lid removably seals the bottom opening of the bottom cavity, wherein removable attachment of the bottom lid to the main body allows the at least one article to be removably concealed within the bottom cavity.

US Pat. No. 10,427,824

BEVERAGE BOTTLE

Viewtec Japan Co., Ltd., ...

1. A beverage bottle comprising:a bottle body having a volume-reducing structure capable of reducing the volume of the bottle body;
a cap capable of sealing an opening of the bottle body; and
a shrunken state-maintaining means provided on said bottle body to cause the bottle body having been reduced in volume to be maintained in the reduced volume state while containing liquid contents,
wherein said volume-reducing structure is configured of substantially longitudinal helical protrusions and recesses respectively formed on the bottle body, and said shrunken state-maintaining means is provided on a trunk section of the bottle body at a substantially central longitudinal portion of the trunk section, and is configured with an integral squeezing means for squeezing and maintaining the trunk section having been narrowed by being squeezed along said helical protrusions and recesses, and,
wherein said bottle body maintains the shrunken state created thereby, while containing liquid contents.

US Pat. No. 10,427,823

LIGHTWEIGHT NECK FINISH FOR A CONTAINER

Silgan White Cap LLC, Do...

1. A container comprising:a body portion defining an interior; and
a neck finish comprising:
a cylindrical neck having a first end and a second end;
a channel extending between the first end and the second end of the neck;
the first end of the neck being attached to and extending from an upper end of the body portion;
the second end of the neck defining an opening configured to provide for fluid communication between the interior of the body portion and a location outside the container;
a thread extending about an exterior surface of an upper portion of the neck, the thread configured to engage a corresponding engagement structure on a closure to seal the opening when a closure is attached to the neck; and
a retention element extending outwardly from the exterior surface of the neck at a location below a lowermost portion of the thread, the retention element configured to engage a corresponding retention structure on a tamper band portion of a closure upon initial removal of a closure formed with a tamper band from the neck of the container, the retention element comprising:
a first structure comprising:
an upper surface extending between a first end and a second end, the first end of the upper surface attached to the exterior surface of the neck; and
a lower surface extending between a first end and a second end, the first end of the lower surface being attached to the exterior surface of the neck;
the second end of the upper surface and the second end of the lower surface each being located radially outwards relative to the exterior surface of the neck at substantially the same distance as measured from a vertical axis about which the neck is centered;
the second end of the upper surface and the second end of the lower surface each being located at substantially the same height along the vertical axis;
the upper surface extending between the upper surface first end and the upper surface second end along a curve; and
a second structure comprising:
a circumferentially extending main body portion having an uppermost end attached to and extending downwards from a bottom end of the lower surface of the first structure;
a radially outermost portion of an exterior surface of the main body being located radially inwards relative to each of the second ends of the of the upper and lower surfaces of the first structure;
a lowermost end of the exterior surface of the main body being located radially outwards relative to the exterior surface of the neck and radially inwards relative to each of the second ends of the of the upper and lower surfaces of the first structure; and
a circumferentially extending groove formed within and extending circumferentially about at least a portion of the main body at a height along the main body located between the uppermost end and the lowermost end;
the circumferentially extending groove having a height as measured along the vertical axis and a length as measured in a circumferential direction, the length of the circumferentially extending groove being greater than the height of the circumferentially extending groove.

US Pat. No. 10,427,822

CONTAINERS AND RECYCLABLE TAMPER-EVIDENT CLOSURE ASSEMBLIES

GUALA CLOSURES S.P.A., A...

1. An assembly, comprising:a container with a neck and a mouth, said neck extending along a longitudinal axis and terminating on top in an annular rim that delimits the mouth,
a tamper-evident closure coupled to said container for opening and closing said mouth, said neck comprising:
a tubular wall extending along said longitudinal axis between a lower portion and an upper portion, the annular rim being formed at a upper end of the upper portion,
threads formed outside the tubular wall, longitudinally beneath and adjacent to said annular rim, such threads having a minimum diameter D1 and a maximum diameter D2 and longitudinally extending between a lower end of the threads and an upper end of the threads,
a projection formed outside the tubular wall longitudinally beneath said lower end of the threads, said projection having a maximum diameter D3 that is greater than the minimum diameter D1 of the threads and less than or equal to the maximum diameter D2 of the threads,
a groove formed in the projection and extending in a circumferential or helical direction, with a minimum diameter D4 that is less than the maximum diameter D3 of the projection and less than the maximum diameter D2 of the threads, between a first end of the groove and a second end of the groove,
a ramp extending in the circumferential or helical direction to join the second end of the groove with a portion of the projection, to thereby join the minimum diameter D4 of the groove to the maximum diameter D3 of the projection, and
said tamper-evident closure comprising:
a closure member configured to open and close said mouth, said closure member comprising a top wall and a sleeve, the sleeve being arranged coaxially outside the neck and longitudinally extending between said top wall and a bottom edge of the sleeve, said sleeve comprising threads removably engaged with the threads of the container,
a skirt arranged coaxially outside the neck and longitudinally beneath the sleeve, said skirt longitudinally extending with a maximum diameter D5 between a top edge of the skirt and a bottom edge of the skirt, the top edge of the skirt being connected to the bottom edge of the sleeve using a frangible portion, which is configured to break upon first opening to allow removal of the closure member from the neck, said skirt having a first attachment portion and a second attachment portion, said first attachment portion being engaged in the groove to hold the skirt longitudinally attached to the neck upon the first opening and extending with a minimum diameter D6 between the first end of the groove and the second end of the groove, said second attachment portion being engaged with the ramp to join the first attachment portion having the minimum diameter D6 with a skirt portion having the maximum diameter D5,
so that, upon removal of the closure member from the neck, the skirt can be rotated relative to the neck to bring the first attachment portion to engage against the ramp and enlarge its diameter to the maximum diameter D5 to thereby disengage the first attachment portion from the groove and allow the skirt to be slid off the neck.

US Pat. No. 10,427,821

DELAMINATED CONTAINER MANUFACTURING METHOD AND AIR LEAK INSPECTION METHOD FOR DELAMINATED CONTAINER

KYORAKU CO., LTD., Kyoto...

1. A method of manufacturing a delaminatable container, comprising:forming a container body having an outer shell and an inner bag; and
preliminarily delaminating the inner bag from the outer shell in an entire circumference of a storage portion of the container body by rotating the container body while pressing the storage portion with a pressing mechanism from outside for compression or by moving the pressing mechanism along an outer circumference of the container body.

US Pat. No. 10,427,820

AUTOMATIC HIGH SPEED; LABELING SYSTEM HAVING AN IMPROVED LABEL STRIPPER

Sinclair Systems Internat...

1. An automatic, high speed produce labeling machine wherein a label applicator having a plurality of bellows carried on a rotary head includes a label stripper to strip individual labels from a label carrier strip and transfer said labels onto the tip of a single bellow, and thereafter onto individual items of produce wherein said label carrier strip has first and second edges, is drawn across said label stripper surface to separate individual labels from the center of said label carrier strip, and wherein said label carrier strip periodically becomes misaligned relative to said label stripper surface, the improved label stripper characterized by:said label stripper having a body, two mounting ears and a contoured surface;
said contoured surface including a central stripping segment and first and second separation segments;
said central stripping segment is positioned on the center of the pathway of said carrier strip to engage and strip said labels as said carrier strip is drawn across said label stripper;
said first and second separation segments are positioned laterally on opposite sides of said central stripping segment; and
both separation segments have surfaces inclined in a direction away from the path of said carrier strip, whereby as a label is stripped by said central stripping segment, said first and second edges of said carrier strip are separated from said contoured surface by said separation segments and do not contact said contoured surface of said label stripper, minimizing tension in said first and second edges of said carrier strip and maximizing tension in the center of said carrier strip.

US Pat. No. 10,427,819

PLURAL-MODE AUTOMATIC MEDICAMENT PACKAGING SYSTEM

CHUDY GROUP, LLC, Powers...

1. A plural-mode automatic medicament packaging system for making patient-specific compliance packages consisting of pouch packages or blister packages loaded with different types of medicaments in the sequence in which they are to be taken by the patient, the system comprising:a controller operable to control the system to make the patient-specific compliance packages in accordance with each patient's prescription order,
an automatic medicament dispensing unit in data-transmission relationship with the controller, the dispensing unit including a plurality of medicament storage and dispensing units collectively holding quantities of different types of medicaments, the storage and dispensing units being controlled by the controller in accordance with each patient's prescription order to dispense the type and quantity of each different type of medicament required to load pouch packages of a series of pouch packages or to load cells of a blister Package in the sequence in which the medicaments are to be taken by the patient;
a pouch packaging unit in data-transmission relationship with the controller which receives the medicaments dispensed from the storage and dispensing units, the pouch packaging unit being controlled by the controller in accordance with each patient's prescription order to package the medicaments in the pouch packages of the series of pouch packages such that the type and quantity of the different types of medicaments are arranged in successive pouch packages in the sequence in which they are to be taken by the patient;
a blister package packaging unit in data-transmission relationship with the controller which receives the medicaments dispensed from the storage and dispensing units, the blister packaging unit being controlled by the controller in accordance with each patient's prescription order to package the medicaments in the cells of the blister package such that the type and quantity of the different types of medicaments are arranged in successive cells in the sequence in which they are to be taken by the patient, the blister package packaging unit including:
a robotic pick-and-place device which loads any of the medicaments into any cell of the blister package to arrange the type and quantity of the different types of medicaments in the cells in the sequence in which they are to be taken by the patient; and
a scaler unit which seals the blister package after loading; and
a plural-position medicament diverter apart from the storage and dispensing units and in data-transmission relationship with the controller, the diverter being controlled by the controller and having first and second mode positions such that, in the first-mode position, the medicaments move from the storage and dispensing units to the pouch packaging unit and, in the second-mode position, the diverter is controlled such that medicaments move from the storage and dispensing units to the diverter and the diverter delivers the medicaments to the blister package packaging unit enabling the robotic pick-and-place device to load and arrange the different types of medicaments into the blister package cells in the sequence in which they are to be taken by the patient.

US Pat. No. 10,427,818

STRAPPING APPARATUS, STRAPPING METHOD AND PAPER SHEETS PROCESSING APPARATUS

Kabushiki Kaisha Toshiba,...

1. A strapping apparatus comprising:a main controller that sets a denomination of paper sheets to be strapped, and
determines a color of a strap band to strap a bundle of the paper sheets, based on the denomination;
a strap band supply device that stores a first strap band reel having strap bands to be supplied;
an imaging device that acquires an image of the first strap band reel;
a sub-controller that decides a color of the first strap band reel, based on the image; wherein
the main controller presents a warning via a monitor if the color of the first strap band reel is different from the color determined by the main controller; wherein the sub-controller decides a remaining quantity of the first strap band reel, based on the image, the strap band supply device further stores a second strap band reel, the sub-controller makes the strap band supply device supply strap bands from the second strap band reel if the remaining quantity of the first strap band reel is less than a predetermined remaining quantity, and the main controller presents the warning via the monitor if a color of the second strap band reel is different from the color determined by the main controller and if the remaining quantity of the first strap band reel is less than the predetermined remaining quantity.

US Pat. No. 10,427,817

SHAFT SYSTEM COMPRISING A PLURALITY OF RECEIVING SHAFTS ARRANGED IN PARALLEL SIDE BY SIDE FOR RECEIVING FOIL BAGS

INDAG POUCH PARTNERS GMBH...

1. A shaft system comprising:a plurality of exchangeable format parts forming walls of a plurality of receiving shafts arranged in parallel side by side for receiving foil bags,
wherein at side surfaces of the format parts which guide the foil bags, the format parts have lateral recesses of a depth (d), the depth of the recesses of two neighboring format parts defining a width (b) of the receiving shaft formed between them and a shape of the recesses of two neighboring format parts defining a contour of the receiving shaft formed between them,
wherein the width and/or the contour of the receiving shafts is changeable by replacing a first group of exchangeable format parts of said plurality of exchangeable format parts with a second group of exchangeable format parts of said plurality of exchangeable format parts, wherein each of the format parts of the first group comprises one or more recesses with a different depth and/or shape than the format parts of the second group; and
a plurality of holding elements for fastening the format parts to a frame at a rear side of the receiving shafts, wherein each of said holding elements is fastened to a respective wall of the frame, the respective walls being fastened side by side to a cross beam, or wherein the holding elements are fastened side by side to a continuous wall of the frame.

US Pat. No. 10,427,816

METHOD FOR LAYING MULTIPLE CONDUCTORS IN A CONTAINER

Southwire Company, LLC, ...

1. A method for laying multiple conductors in a container, the method comprising:receiving the multiple conductors from at least one payoff reel at a monitoring station configured to monitor a length of each of the multiple conductors;
passing the multiple conductors through a tension equalization capstan;
receiving the multiple conductors at a variable speed drive; and
receiving the multiple conductors at the container.

US Pat. No. 10,427,815

METHOD AND DEVICE FOR PRODUCING PACKAGES

KHS GmbH, Dortmund (DE)

1. An apparatus for forming a container package, said apparatus comprising a guide rail, a container inlet, a first container treatment section, a second container treatment section, a first adhesive-applicator, a second adhesive-applicator, a transport section, a first clamp head, and a second clamp head, wherein said container inlet is configured for receiving a two-lane container stream, wherein said first treatment section receives a first lane of said container stream, wherein said second treatment section receives a second lane of said container stream, wherein said first adhesive applicator is configured to apply adhesive to containers in said first treatment section, wherein said second adhesive applicator is configured to apply adhesive to containers in said second treatment section, wherein said transport section follows said first and second treatment section, wherein said transport section conveys an at least two-lane container stream along a transport direction, wherein said first clamp head and said second clamp head cooperate to separate containers moving along said transport direction into container groups, wherein, in operation, said first and second clamp heads each comprise a container holder configured to grip a container on a surface thereof, wherein said first and second clamp heads are disposed to move together along said transport section opposite each other, wherein said first and second clamp heads are configured to cooperate to compress containers in a container group together so that adhesive applied to said containers binds said containers together to form said container package, wherein said clamp head comprises a headpiece that forms said container holder and a trolley that is guided on said guide rail, said headpiece being configured to be slid in a controlled manner and guided on said trolley for executing a delivery and clamping movement, and wherein said head piece is exchangeable for other head pieces to accommodate different container formats.

US Pat. No. 10,427,814

CONTINUOUS ROTARY WIRE TIE ASSEMBLY

Accent Packaging, Inc., ...

1. A gear-train for driving a wire tying assembly, the gear-train comprising:a main-drive gear configured to be continuously driven in a first direction throughout the duration of a wire tying cycle;
an idler gear having a first dwell portion and a second dwell portion, the idler gear being configured to mesh with the main-drive gear during a portion of the wire tying cycle and to dwell relative to the main-drive gear during a portion of the wire tying cycle when the first dwell portion is adjacent to the main-drive gear; and
a twister pinion gear having a wire receiving channel and configured to be in mesh with the idler gear during a portion of the wire tying cycle and to dwell relative to the idler gear during a portion of the wire tying cycle when the second dwell portion is adjacent to the twister pinion gear.

US Pat. No. 10,427,812

ALL-MODEL ALUMINUM PRODUCT AUTOMATIC PACKING MACHINE

GUANGDONG JMA ALUMINIUM P...

1. An automatic packing machine, comprising:a rack;
a packing mechanism disposed on the rack; and
a feeding mechanism configured to deliver aluminum products to the packing mechanism;
wherein:
the packing mechanism comprises universal clamps symmetrically disposed at two ends of the rack and being configured to fix the aluminum products, the universal clamps being further configured to:
rotate under driving of a rotating motor, and
stretch forward and retract backward under driving of a pneumatic push rod; and
the rack includes a packing platform, and the packing platform includes a pressing piece provided at one side of the packing platform corresponding to the universal clamps and capable of turning upward.

US Pat. No. 10,427,811

DEVICE FOR FILLING A CONTAINER

KRONES AG, Neutraubling ...

1. A device for filling a container with a fill product comprising:a fill product reservoir comprising a valve disposed in a base of the fill product reservoir;
a dosing cylinder comprising a dosing piston configured to be displaceable for dosing the fill product; and
a discharge channel comprising an outlet end that discharges the fill product into the container and a discharge plunger that expels a product residue at an end of a filling process, wherein:
the fill product reservoir, the dosing cylinder, and the discharge channel are in communication with each other via a product channel,
the valve opens and closes a connection between the fill product reservoir and the product channel,
the discharge channel is in communication with the dosing cylinder via an inclined section of the product channel,
a lower blocking edge of the inclined section is disposed at a level below a level defined by a lower center of the dosing piston,
a lower edge of a wall of the dosing cylinder proximate to the fill product reservoir is disposed at a level that is higher than the lower blocking edge of the inclined section,
at the end of the filling process, when no further fill product is being conveyed through the product channel, the discharge plunger, by adopting its lowered position, is configured to expel fill product that is still present in the discharge channel through the outlet end, and
an aperture in the base of the fill product reservoir is disposed at a higher level than the level defined by the lower center of the dosing piston.

US Pat. No. 10,427,809

PHARMACY PACKAGING SYSTEM

RXSAFE LLC, Vista, CA (U...

1. A system for storing and packaging pharmaceuticals, the system comprising:a frame configured to store cassettes that contain pharmaceuticals;
a cassette-moving assembly coupled to the frame, the cassette-moving assembly operable to move relative to the frame to retrieve the cassettes from the frame;
a dispensing area positioned adjacent the frame to receive the cassettes from the cassette-moving assembly, the dispensing area operable to selectively open the cassettes;
packaging equipment in communication with the dispensing area, the packaging equipment including a feed stock roll for forming pouches, the packaging equipment operable to fill the pouches with pharmaceuticals that are dispensed from the cassettes in the dispensing area;
a control system coupled to the cassette-moving assembly and the packaging equipment to control operation of the cassette-moving assembly and the packaging equipment;
a chute connecting the dispensing area to the packaging equipment, the chute including a plurality of tracks, each track corresponding to one of the cassettes supported on the dispensing area; and
a receptacle supported by the packing equipment between the chute and the feed stock roll,
wherein the plurality of tracks converge to direct the pharmaceuticals that are dispensed from the cassettes into the receptacle, and wherein receptacle directs the pharmaceuticals received from the plurality of tracks as a group into the pouches formed by the feed stock roll,
wherein the dispensing area is configured to simultaneously support more than one cassette.

US Pat. No. 10,427,807

METHOD OF FABRICATING A FLEXIBLE, LOW-DENSITY THERMAL PROTECTION MATERIAL

United States of America ...

1. A method of fabricating a low-density thermal protection material, the method comprising:providing a flexible substrate;
providing a slurry including a carrier liquid and pyrolizable thermoset resin particles that have already been cured and that are immersed in, but not soluble in, the carrier liquid;
impregnating the slurry into the substrate to form an impregnated substrate; and
removing the carrier liquid from the impregnated substrate to provide said low-density thermal protection material that remains flexible after the thermoset resin particles are fully pyrolized.

US Pat. No. 10,427,806

DEPLOYMENT AND CONTROL ALGORITHMS FOR WHEEL CLUSTER FORMATIONS OF SATELLITES

The Aerospace Corporation...

1. A process for controlling a companion satellite in a wheel orbit formation, comprising:determining, by at least one processor, one or more deviations in an orbit of the companion satellite; and
controlling, by the at least one processor, the companion satellite to minimize effects of perturbing forces, wherein
the determining of the one or more deviations comprises determining the one or more deviations in eccentricity vector components es and ec,
the one or more deviations caused by a difference in the perturbing forces between a center satellite and the companion satellite.

US Pat. No. 10,427,804

ORBITAL MECHANICS OF IMPULSIVE LAUNCH

QUICKLAUNCH, INC., Carme...

1. A method of launching a vehicle to orbit about Earth, wherein the method comprises launching the vehicle in a direction that is easterly or due east using an impulsive force and along a trajectory that defines an elliptical orbital path, whereina. the elliptical orbital path has an apogee and a perigee;
b. the direction of launch is in a plane corresponding to the elliptical orbital path of the vehicle;
c. the vehicle's trajectory apogee is closely matched to (1) an orbital altitude of a space object or (2) a place of rendezvous with the space object,
d. the vehicle has a fly-out time from a launch site, said fly-out time being measured from a launch time to a time that the vehicle first achieves the vehicle's trajectory apogee, and
e. the vehicle launch occurs about one-third of said fly-out time prior to the space object passing overhead of a position of the launch site at the launch time.

US Pat. No. 10,427,803

ANCHORING VEHICLE FOR ANCHORING AN AIRSHIP AT THE TAIL WHILST COUPLED TO A MOORING-MAST AT THE BOW

1. An anchoring vehicle for anchoring an airship at a tail of the airship, comprising:a height adjustable anchoring-mast mounted to said anchoring vehicle with a ball and socket joint, a coupling location of said anchoring-mast being positioned at a height of a middle axis of the airship, the anchoring mast comprising:
a) coupling devices and spring devices,
b) a minimum of three suspension cables each equipped with a force sensor, or a minimum of two sensors that sense force/strain in two different directions and that are integrated in a rigid coupling of the anchoring-mast; and
c) a measuring device for measuring horizontal wind force upon the airship arranged on the anchoring vehicle,
at least three wheels that are drivable and steerable, and
a control unit and servomotors for steering and driving the wheels depending on measured values of the force sensors, enabling the anchoring vehicle to independently move in a horizontal direction to the airship's position dictated by the wind direction.

US Pat. No. 10,427,802

STABILIZED AGGREGATES AND OTHER MATERIALS AND STRUCTURES FOR ENERGY ABSORPTION

Engineered Arresting Syst...

1. A method of forming a structure for arresting aircraft as an extension area of a runway, comprising:a. positioning a plurality of anchors in the extension area;
b. attaching at least one net to the plurality of anchors;
c. positioning loose aggregate so that its location in the extension area is stabilized at least in part by the plurality of anchors and the at least one net;
d. introducing into the extension area a first material different than the loose aggregate; and
e. coating at least the first material with a water-resistant material.

US Pat. No. 10,427,800

AIR SEPARATION SYSTEM FOR FUEL STABILIZATION

HAMILTON SUNDSTRAND CORPO...

1. A system for generating inert gas comprising:a source of pressurized air for generating a pressurized air flow;
an air separation module located downstream from and in fluid communication with said source of pressurized air, said air separation module including at least one permeable membrane operable to separate said pressurized air into an oxygen-enriched air and an inert gas-enriched air, said oxygen-enriched air being separate from said inert gas-enriched air;
a backpressure regulator for continuously maintaining an operational pressure within the air separation module;
a fuel tank containing a fuel, the fuel tank being arranged downstream from said air separation module; and
a conduit for delivering said inert gas-enriched air from said air separation module to said fuel tank, a portion of said conduit being immersed within said fuel of said fuel tank such that said inert gas-enriched air delivered to said fuel tank interacts directly with said fuel to remove dissolved oxygen from said fuel.

US Pat. No. 10,427,799

TRIMMING DEVICE FOR CONTROLLING THE GLIDE SLOPE AND DESCENT SPEED OF A PARAFOIL

The Charles Stark Draper ...

15. A system for adjusting a trim angle during flight to control glide slope and descent speed of a parafoil, the system comprising: a canopy having a forward portion and an aft portion; a forward suspension line coupled to the forward portion; an aft suspension line coupled to the aft portion;first and second pulleys coupled to suspension lines of the parafoil, wherein the first pulley has a first diameter and the second pulley has a second diameter greater than the first diameter, wherein the forward suspension line of the parafoil is coupled to the first pulley, and wherein the aft suspension line of the parafoil is coupled to the second pulley;
an additional suspension line coupled to one of the forward portion of the canopy or the aft portion of the canopy, wherein the additional suspension line is further coupled to an axle of the first pulley and the second pulley;
a motor coupled to the first and second pulleys; and
a processor operatively coupled to the motor, wherein the processor causes the motor to rotate the first and second pulleys to extend or retract the suspension lines to adjust the trim angle during flight.

US Pat. No. 10,427,798

METHODS AND SYSTEM FOR DEICING A SURFACE

Unmanned AeroSpace Techno...

1. A method comprising:receiving first data from at least one first sensor;
wherein the at least one first sensor is configured to supply data related to:
(i) a thickness of an ice layer on a coated skin surface;
wherein the coated skin surface comprises a coating on a surface of a skin;
wherein the skin comprises a composite including first and second layers, wherein one of the first and second layers is a structural layer;
calculating the thickness of the ice layer;
comparing the thickness of the ice layer to a threshold thickness;
based, at least in part, on the comparing the thickness of the ice layer to the threshold thickness, vibrating the coated skin surface using at least one mechanical element for a sufficient duration, sufficient frequency, and sufficient displacement so as to result in removal of a first portion of the ice layer thereby resulting in at least a partially deiced coated skin surface;
wherein the at least one mechanical element comprises a linear actuator, the linear actuator comprising a cylinder coupled to a rotation mechanism, the linear actuator configured to convert rotational movement of the rotation mechanism to linear movement to linearly displace the cylinder;
wherein the sufficient frequency ranges from 0.01 to 1000 hertz; and
wherein the sufficient displacement of each of the at least one mechanical elements ranges from 2 millimeter to 15 millimeters.

US Pat. No. 10,427,797

SYSTEMS AND METHODS FOR REDUCING ENVIRONMENTAL CONTROL SYSTEM MAINTENANCE

Honeywell International I...

1. A fluid flow regulating system of a vehicle, the system comprising:a ram duct configured to accept fluid flow into the vehicle;
a fluid flow regulating mechanism coupled to the ram duct and coupled to a processing system of the vehicle; and
at least one heat exchanger coupled to a cabin of the vehicle and the ram duct and configured to cool air flowing through the at least one heat exchanger using ram fluid flowing through the ram duct;
wherein the fluid flow regulating mechanism is controlled by the processing system of the vehicle to adjust a size of an opening of the ram duct to regulate the amount of ram fluid flowing through the ram duct based upon at least one pollution parameter.

US Pat. No. 10,427,796

AIR DISTRIBUTION SYSTEM AND METHOD FOR AN AIR CONDITIONING SYSTEM IN AN AIR VEHICLE

The Boeing Company, Chic...

1. An air distribution system for an air conditioning system in an air vehicle, the air distribution system comprising:a plurality of lower lobe ducts located below a cabin floor of a cabin of the air vehicle, each of the plurality of lower lobe ducts being in fluid communication with a mix manifold coupled to one or more air conditioning (AC) packs of the air conditioning system in the air vehicle;
a plurality of sidewall riser ducts coupled to the plurality of lower lobe ducts;
a pair of outboard manifold ducts;
a recirculation air duct located in a crown portion of the air distribution system above the cabin floor;
one of, a plurality of recirculation downer ducts, or a plurality of branch recirculation ducts, coupled to the recirculation air duct;
a conditioned air flow, distributed from the one or more AC packs, through the mix manifold, and to one of, the plurality of lower lobe ducts, or the plurality of lower lobe ducts and then the plurality of sidewall riser ducts;
a recirculated air flow, distributed from the recirculation air duct, to one of, the plurality of recirculation downer ducts, or the plurality of branch recirculation ducts; and
a mixed air flow formed by mixing the conditioned air flow and the recirculated air flow, the mixed air flow distributed to the pair of outboard manifold ducts, and into the cabin of the air vehicle.

US Pat. No. 10,427,795

VARYING A CROSS SECTION OF A RAM AIR PASSAGE

Airbus Operations GmbH, ...

1. An apparatus comprising:a ramp configured to enable variation of a cross section of a ram air passage of the apparatus, wherein the ramp comprises:
a first rigid member;
a second rigid member; and
a flexible member coupled to the first rigid member and the second rigid member,
wherein the ramp is movably mounted at two ends; and
an actuator external to the ramp which is configured to act upon the ramp for moving the ramp,
wherein the actuator is mechanically coupled only to a center region of the flexible member so that a radius of curvature of the flexible member substantially decreases as the cross section of the ram air passage decreases, and
wherein the ramp is configured to entirely close the ram air passage.

US Pat. No. 10,427,793

SLOUCHING DIVAN WITH DAMPED MOTION

Rockwell Collins, Inc., ...

1. A slouching divan with damped motion, comprising:at least one front leg and at least one rear leg, the front leg and the rear leg mountable to a floor of an aircraft;
at least one frame rail connecting the front leg and the rear leg, the frame rail including at least one lateral roller slot extending in a downward slope from a rear endpoint associated with an upright configuration to a midpoint associated with a slouched configuration, and extending in an upward slope from the midpoint to a front endpoint associated with a berthed configuration;
at least one seatpan having a front end and a rear end, the seatpan slidably connectable to the lateral roller slot, the seatpan at least partially coverable by a seatpan cushion;
at least one seatpan rail coupled to the seatpan proximate to the lateral roller slot;
at least one backrest having a top, a bottom, and at least one back roller slot extending from the top to the bottom in a rearward curving path;
at least one back follower panel slidably connectable to the back roller slot and coupled to the seatpan proximate the bottom and the rear end by at least one connector, such that the back follower panel follows the movement of the seatpan along the lateral roller slot, the back follower panel at least partially coverable by a backrest cushion; and
at least one unidirectional damping device coupled to the frame rail, the damping device configured to constrain the movement of the seatpan from the upright configuration to the slouched configuration by engaging with the seatpan rail.

US Pat. No. 10,427,792

VEHICLE WITH A SIMULATED WINDOW FEATURE

The Boeing Company, Chic...

9. A display system for a lavatory of a vehicle, wherein the display system is configured to resemble a window of the vehicle, the display system comprising:a bezel disposed about a boundary of a cutout formed in a wall of the lavatory;
a fixture configured as a continuous member mounted exterior to the wall of the lavatory behind the bezel; and
an electronic display mounted in the fixture, such that the electronic display is visible from within the lavatory through the bezel, wherein the wall of the lavatory is curved to match curvature of a body of the vehicle, wherein the electronic display is flat, wherein the fixture is ring-shaped and has variable thickness such that a top edge and a bottom edge of the fixture are thicker than a middle section of the fixture so as to accommodate curvature of the wall of the lavatory.