US Pat. No. 10,508,020

SUBSTRATE STRUCTURE, SEMICONDUCTOR STRUCTURE AND METHOD FOR FABRICATING THE SAME

TAIWAN SEMICONDUCTOR MANU...

1. A substrate structure for a micro electro mechanical system (MEMS) device, comprising:a cap defining a cavity, wherein the cap is a semiconductor substrate;
a micro electro mechanical system (MEMS) substrate disposed on the cap, the MEMS substrate having a plurality of through holes directly exposing the cavity, and an aspect ratio of the plurality of through holes being greater than 30, the MEMS substrate having a first substrate, a second substrate, an adhesive and a third substrate, the first substrate having a plurality of first sub-through holes exposing the cavity, the second substrate having a plurality of second sub-through holes substantially aligned with the plurality of first sub-through holes, the third substrate having a plurality of third sub-through holes substantially aligned with the plurality of second sub-through holes, wherein the second substrate and the third substrate are bonded to each other using the adhesive, the plurality of first sub-through holes, the plurality of second sub-through holes, and the plurality of third sub-through holes form the plurality of through holes; and
a device substrate above a surface of the MEMS substrate facing away from the cap.

US Pat. No. 10,508,017

POINT-OF-SALE OCTANE/CETANE-ON-DEMAND SYSTEMS FOR AUTOMOTIVE ENGINES

Saudi Arabian Oil Company...

1. A point-of-sale fuel dispensing system comprising:a market fuel storage tank;
a pump assembly comprising:
a customer interface for retail payment and fuel grade selection; and
a nozzle configured to provide selective fluid coupling to a fuel supply port of a vehicle that is situated adjacent the pump assembly;
fuel conduit cooperative with the pump assembly and the market fuel storage tank to provide selective fluid communication between the pump assembly and the market fuel storage tank;
a separation unit configured to selectively receive and convert at least a portion of a market fuel into an octane-rich fuel component and a cetane-rich fuel component;
a plurality of enriched fuel product tanks disposed fluidly intermediate the separation unit and the pump assembly, the plurality of enriched fuel product tanks comprising:
a first enriched fuel product tank for selectively receiving and containing the octane-rich fuel component; and
a second enriched fuel product tank for selectively receiving and containing the cetane-rich fuel component; and
a controller cooperative with at least one of the market fuel storage tank, pump assembly, fuel conduit, separation unit and first and second enriched fuel product tanks to direct the flow of at least a portion of at least one of the octane-rich fuel component and the cetane-rich fuel component contained within a respective one of the first and second product tanks through the nozzle based on user input at the customer interface for both retail payment and fuel grade selection for the vehicle, wherein the directed flow does not exceed a fuel storage capacity of the vehicle.

US Pat. No. 10,508,010

SHOPPING FACILITY DISCARDED ITEM SORTING SYSTEMS, DEVICES AND METHODS

Walmart Apollo, LLC, Ben...

1. A system for sorting items discarded in a shopping facility, comprising:a motorized transport unit configured to travel around discarded items collected from the shopping facility and placed in a sorting area in the shopping facility, the motorized transport unit comprises a sensor device and an item mover device;
an item characterization database storing characteristics corresponding to a plurality of items likely to be found in the shopping facility; and
a central computer system coupled to the motorized transport unit and the item characterization database, and configured to:
receive data from the sensor device on the motorized transport unit;
determine an item characteristic of an item among the discarded items in the sorting area based on the data from the sensor device;
determine a sorting category of the item from a plurality of predefined categories based on the item characterization database, each of the plurality of predefined categories corresponds to a method of discarded item deposition; and
cause the motorized transport unit to move the item, with the item mover device, from the sorting area into a category area associated with the sorting category.

US Pat. No. 10,508,005

ASSEMBLY FOR LIFTING OR SUPPORTING A LOAD, AND MEMBERS AND CONNECTORS FOR USE IN SAME

1. An assembly for use with a spreader bar arrangement, a crane, or as part of a frame for a building structure, comprising:a plurality of members connectable in an assembled arrangement for supporting, carrying or distributing a load;
each member comprising two ends, each end having two connecting members, each connecting member consisting essentially of two lugs, each lug having a hole therethrough; a first pair of the lugs of the connecting members are located at opposing edges of the end of the member and a second pair of the lugs of the connecting members are vertically spaced from the first pair with each lug in the second pair being horizontally offset from the respective opposing edge of the end of the member, the first and second pair of lugs are each symmetrically arranged about a centerline of the end of the member; and the first pair of lugs and the second pair of lugs are spaced at a different distance from the centerline of the end of the member;
which pair of connecting members are configured for interconnection when inverted 180 degrees about a longitudinal axis of the pair of connecting members with a corresponding pair of identically arranged connecting members formed on another member in said assembly for connection thereto; and
fasteners that each comprise a shaft that extend through the holes formed in said lugs when the holes in the lugs of each pair of connecting members are aligned with the holes in the lugs of the corresponding pair of connecting members on the other member.

US Pat. No. 10,507,992

CONVEYOR SYSTEMS INCLUDING DOLLIES WITH AUTOMATIC UNLOADING MULTI-BAR LINKAGE SYSTEMS FOR AUTOMATICALLY UNLOADING A DOLLY

1. An automatic unloading dolly that automatically unloads pallets therefrom, the automatic unloading dolly comprising:a frame having a loading/unloading side and a pusher side;
a conveyor platform that extends between the loading/unloading side and the pusher side;
one or more wheels connected to the frame;
a multi-bar linkage system mounted to the frame and connected to a pusher that moves along the conveyor platform from the pusher side toward the loading/unloading side between a pusher base position and a pusher triggered position; and
a contact arm link connected to the multi-bar linkage system such that movement of the contact arm link relative to the frame from a contact arm link base position to a contact arm link triggered position moves the multi-bar linkage system and the pusher from the pusher base position to the pusher triggered position.

US Pat. No. 10,507,991

VACUUM CONVEYOR SUBSTRATE LOADING MODULE

APPLIED MATERIALS, INC., ...

1. A loading module for a substrate inspection system, the loading module comprising:a first conveyor module; and
a second conveyor module having a movable surface positioned substantially parallel to a movable surface of the first conveyor module, wherein the first conveyor module includes a first section and a second section, the first section having a vacuum unit operable to secure a substrate to a portion of the movable surface in the first section, and the second section is configured to release the substrate from the movable surface of the first conveyor module in a falling position that is at an acute angle relative to a horizontal plane.

US Pat. No. 10,507,982

GRAVITY FEED INVENTORY MANAGEMENT

Amazon Technologies, Inc....

1. An inventory storage system, comprising:a gravity feed conveyance system configured to route a plurality of inventory items to a plurality of container holders by allowing rollable containers that contain individual ones of the plurality of inventory items to roll along the gravity feed conveyance system under the force of gravity, and to exit the gravity feed conveyance system via a plurality of exits having respective sizes associated with respective critical dimensions of the rollable containers;
a first container holder of the plurality of container holders configured to receive a first rollable container having a first critical dimension responsive to the first rollable container exiting the gravity feed conveyance system via a first exit having a first size associated with the first critical dimension; and
a second container holder of the plurality of container holders configured to receive a second rollable container having a second critical dimension responsive to the second rollable container exiting the gravity feed conveyance system via a second exit having a second size associated with the second critical dimension;
wherein the first critical dimension is different than the second critical dimension; and
wherein the first size of the first exit is different than the second size of the second exit.

US Pat. No. 10,507,975

CONVEYOR AND LOGIC SYSTEMS TO RETURN, BALANCE, AND BUFFER PROCESSED OR EMPTY TOTES

Walmart Apollo, LLC, Ben...

14. A method for distributing empty totes from a first area, the method comprising:moving empty totes along a first conveyor line coupled to a first buffer component, the first conveyor line connecting a first consolidation area to a first picking area, the first conveyor line comprising a first plurality of sensors configured to detect partial and full capacity near the first picking area, the first plurality of sensors including at least a first overflow sensor;
signaling a control circuit via the first overflow sensor when the first conveyor line reaches a specified capacity of empty totes;
moving empty totes along a second conveyor line coupled to a second buffer component, the second conveyor line connecting a second consolidation area to a second picking area, the second conveyor line coupled to a second plurality of sensors configured to detect partial and full capacity near the second picking area, the second plurality of sensors including at least a second overflow sensor;
signaling the control circuit via the first overflow sensor when the first conveyor line reaches the specified capacity of empty totes;
receiving signals from the first plurality of sensors and second plurality of sensors at the control circuit; and
generating by the control circuit a control signal to activate at least one transfer device to direct totes from at least one of the first conveyor line or second conveyor line to a respective at least one of the first and second buffer components based on signals received from the plurality of sensors of the other conveyor line;
receiving the control signal at a transfer device located along one of the first conveyor line and the second conveyor line.

US Pat. No. 10,507,968

MODULAR BOX ASSEMBLY

Pratt Retail Specialties,...

1. A modular box assembly comprising:a box having a top end and an opposed bottom end, the box comprising:
a first side panel, a third side panel opposed to the first side panel, a second side panel positioned between and coupled to the first side panel and the third side panel, and a fourth side panel opposed to the second side panel, the fourth side panel being positioned between and coupled to the first and third side panels, wherein each of the side panels extends from the top end to the bottom end;
a bottom panel disposed at the bottom end of the box, the bottom panel being coupled to each of the side panels such that the side panels and the bottom panel define a box cavity, and the top end defines a box opening in communication with the box cavity; and
a first shoulder attached to the second side panel, the first shoulder extending inward from the first side panel and the third side panel into the box cavity;
a second shoulder attached to the fourth side panel, the second shoulder extending inward from the first side panel and the third side panel into the box cavity, wherein each shoulder is spaced from the top end a predetermined distance; and
a box top comprising a top panel configured to cover the box opening, the box top being selectively movable about and between a closed position, in which the box top encloses the box cavity, and an open position, in which the box top is spaced from the top end and the box cavity is accessible, wherein in the closed position, a lower surface of the top panel engages the first shoulder and the second shoulder to support the top panel, and in the closed position an upper surface of the top panel is substantially flush with the top end of the box, and wherein the box top further comprises a pair of opposed side tabs extending away from the top panel, and wherein each side tab has a width that is less than a width of the top panel.

US Pat. No. 10,507,962

GLASS SCREEN FILM APPLICATOR AND CARRIER MODULE THEREOF

1. A carrier module of a glass screen film applicator, comprising:a carrier including a mounting slot and an accommodating trough, wherein the carrier defines a longitudinal direction and a width direction perpendicular to the longitudinal direction, and the accommodating trough includes a rail hole recessed in a bottom thereof and parallel to the longitudinal direction; and
a positioning member integrally formed as a one-piece structure and mounted in the mounting slot, wherein the positioning member includes an L-shaped structure and a plurality of positioning pillars extending from the L-shaped structure and arranged in a row parallel to the longitudinal direction, the L-shaped structure has a positioning corner arranged on an inner side of the L-shaped structure, each of the positioning pillars is perpendicular to the longitudinal direction and the width direction, and the positioning corner has two lateral walls parallel to the longitudinal direction and the width direction, respectively,
wherein the positioning corner is configured to abut against a corner of a mobile device, and the positioning pillars are configured to position a glass screen film structure.

US Pat. No. 10,507,951

PACKAGING WITH SPRING LOADED HANGER

Otter Products, LLC, For...

14. A packaging assembly for a product, the packaging assembly comprising:a tray comprising a plurality of sides bounding a cavity for receiving the product;
a sleeve comprising a front wall, a back wall attached to the front wall by a plurality of side walls, a slot extending through one of the plurality of side walls, and an opening for slidably receiving the tray; and
a spring loaded hanger configured to be inserted in the slot in the sleeve, the spring loaded hanger comprising:
a hang point for the packaging assembly;
a lip having a dimension greater than a width of the slot, the lip contacting an inner surface of a wall of the sleeve to prevent the hanger from passing completely through the slot; and
a plurality of spring arms, each spring arm configured to compress between an inside wall surface of one of the plurality of side walls of the sleeve and a side of the tray, the compression deforming the spring arms and providing a spring force to provide friction or static friction between the tray and sleeve to resist the removal of the tray from the sleeve.

US Pat. No. 10,507,949

CONVERTIBLE FOOD CONTAINERS

Amazon Technologies, Inc....

1. A container comprising:a paperboard blank comprising:
a bottom panel;
a first side panel, wherein the first side panel is connected to the bottom panel at a first bottom edge, connected to a first corner panel at a first front edge, connected to a second corner panel at a first rear edge, and connected to a first top panel at a first top edge;
a second side panel, wherein the second side panel is connected to the bottom panel at a second bottom edge, connected to a third corner panel at a second front edge, connected to a fourth corner panel at a second rear edge and connected to a second top panel at a second top edge;
a first end panel, wherein the first end panel is connected to the bottom panel at a third bottom edge, connected to the first corner panel at a first side edge, connected to the third corner panel at a second side edge and connected to a third top panel at a third top edge; and
a second end panel, wherein the second end panel is connected to the bottom panel at a fourth bottom edge, connected to the second corner panel at a third side edge, connected to the fourth corner panel at a fourth side edge, and connected to a fourth top panel at a fourth top edge,
wherein the first side panel is folded upwardly at the first bottom edge with respect to the bottom panel,
wherein the second side panel is folded upwardly at the second bottom edge with respect to the bottom panel,
wherein the first end panel is folded upwardly at the third bottom edge with respect to the bottom panel,
wherein the second end panel is folded upwardly at the fourth bottom edge with respect to the bottom panel,
wherein the first side panel, the second side panel, the first end panel, the second end panel and the bottom panel define a cavity,
wherein a first score substantially bisects the first corner panel on a front face of the paperboard blank,
wherein a second score is provided on a rear face of the paperboard blank and at the first front edge of the first side panel,
wherein a third score is provided on the rear face of the paperboard blank and at the first side edge of the first end panel,
wherein the first corner panel comprises a first radial extension provided between the first score and the second score,
wherein the first corner panel further comprises a second radial extension provided between the first score and the third score,
wherein each of the first radial extension and the second radial extension has a first length,
wherein each of the first score, the second score and the third score has a second length,
wherein the first length is greater than the second length,
wherein the first corner panel is folded into the cavity at the first front edge of the first side panel and at the first side edge of the first end panel,
wherein the second corner panel is folded into the cavity at the first rear edge of the first side panel and at the third side edge of the second end panel,
wherein the third corner panel is folded into the cavity at the second front edge of the second side panel and at the second side edge of the first end panel,
wherein the fourth corner panel is folded into the cavity at the second rear edge of the second side panel and at the fourth side edge of the second end panel,
wherein the first top panel is folded over the cavity at the first top edge of the first side panel,
wherein the second top panel is folded over the cavity at the second top edge of the second side panel,
wherein the third top panel is folded over the cavity at the third top edge of the first end panel,
wherein the fourth top panel is folded over the cavity at the fourth top edge of the second end panel, and
wherein at least one of the first top panel or the third top panel is in contact with at least one of the first radial extension or the second radial extension.

US Pat. No. 10,507,941

LID STORAGE AND APPLICATION DEVICE

1. A container lid application device for applying a lid onto a container, said lid application device comprising:(a) a dispense assembly configured for indexing the lid from a magazine of lids in a first orientation, said magazine of lids terminated at a bottom end of said magazine of lids with a bottommost lid, said dispense assembly comprising at least two magazine support segments biased toward one another forming an opening, each of said at least two magazine support segments is coupled to a plunger such that when each said plunger is urged upwardly, said opening is widened to release the bottommost lid of said magazine of lids before said opening contracts to support the remaining lids of said magazine of lids;
(b) a press assembly comprising:
(i) a lid grasping ring disposed in a first plane, said lid grasping ring comprising a ring member configured for receiving the bottommost lid, said ring member having an opening of a first diameter; and
(ii) a handle attached to a support ring within which said lid grasping ring is disposed;
(c) a transport assembly comprising:
(i) a guide slideably attached to said support ring, said guide configured for guiding said lid grasping ring to the container at a first position in a first direction;
(ii) a return spring attached to said support ring, wherein said return spring is configured to return said lid grasping ring to a second position in a second direction opposite to said first direction; and
(d) a rotator assembly configured for rotating said lid grasping ring to a second orientation that is disposed at about 180 degrees with respect to said first orientation while said press assembly is moved between said first position and said second position,
wherein, when said handle is pulled away from said second position towards said first position with a force, said plunger drops downwardly, the released bottommost lid is received in said opening of said ring member, the released bottommost lid is rotated by said rotator assembly while being transported by said transport assembly before arriving at said first position such that the released bottommost lid is securable to the container by said press assembly.

US Pat. No. 10,507,934

THERMAL MANAGEMENT SYSTEM

United States of America ...

1. An aircraft comprising:a turbine engine generating turbine exhaust;
a thermo-acoustic engine disposed proximate to an exhaust exit point of the turbine engine, wherein the thermo-acoustic engine includes a first heat exchanger, a regenerator, and a second heat exchanger, wherein the first heat exchanger, the regenerator, and the second heat exchanger are disposed within a resonator, wherein heat from the turbine exhaust heats the first heat exchanger such that there is a temperature gradient across the regenerator to generate an acoustic wave throughout the resonator via the thermoacoustic effect;
a transducer configured to convert the acoustic wave into electrical energy; and
an electrical component conductively connected to the transducer such that the electrical component receives the electrical energy, wherein the electrical energy powers operation of the electrical component.

US Pat. No. 10,507,931

PANEL AND INSERT FOR CORNER RADII

Rohr, Inc., Chula Vista,...

1. A panel for an aircraft nacelle, comprising:a first skin;
a second skin;
a first core portion coupled to the first skin and the second skin;
a second core portion coupled to the first skin and the second skin; and
an insert coupled to the first skin, the second skin, the first core portion and the second core portion, the insert forming a corner fitting between the first core portion and the second core portion;
the insert comprising a first core structure and a second core structure bonded to and overlapping the first core structure, wherein the first core structure is adjacent the first skin, and wherein the second core structure is adjacent the second skin.

US Pat. No. 10,507,925

PASSENGER AIRFLOW CONTROL DEVICES

1. A passenger airflow control device comprising:an open-ended domed shell;
a receiver immovably fixed to an upper end of the shell;
a central air distributor assembly operatively connected to the receiver for receiving an incoming airflow and discharging the airflow to a passenger, wherein the central air distributor assembly includes:
(i) a central distributor bowl which defines a laterally oriented airflow discharge opening;
(ii) a central disk which is positionally fixed to and closes a lower end of the central distributor bowl; and
(iii) an air distributor hub having a lower end immovably connected to an upper end of the central distributor bowl and an upper stem which is received within and rotatably connected to the receiver, wherein
(iii) the air distributor hub defines an interior space in fluid communication with the air discharge opening of the central distributor bowl and includes an air inlet cutout which is capable of fluid communication with the incoming airflow, wherein rotational movement of the central air distributor assembly responsively moves the air inlet cutout of the air distributor hub relative to the incoming airflow between open and closed conditions and concurrently moves the discharge opening of the central distributor bowl to allow directional control of the airflow discharged therefrom.

US Pat. No. 10,507,924

SEAT TRACK FITTING

Saftran Seats, Plaisir (...

1. A seat track fitting, comprising:a sleeve comprising a cylindrical threaded opening;
a double effect post comprising an external lower thread and an internal threaded portion, the external lower thread configured to cooperate with the cylindrical threaded opening of the sleeve; and
a track stud comprising a lower flange configured to cooperate with a seat track and an upper external thread configured to cooperate with the internal threaded portion of the double effect post, wherein the double effect post external lower thread and the track stud external thread have inverse hands,
further comprising a seat leg securement element, wherein the seat leg securement element comprises a sleeve-contacting plate with a post-receiving opening, wherein the sleeve further comprises a post, and wherein in use, the post-receiving opening receives the post, the sleeve-contacting plate is positioned against the sleeve, and a seat leg or a seat leg interface part is positioned against an opposite side of the sleeve-contacting plate.

US Pat. No. 10,507,901

PROTECTING AND ENSURING READINESS OF A VEHICLE

THE BOEING COMPANY, Chic...

1. A method, implemented in a computing device, the method comprising:obtaining environmental data, capability data corresponding to a vehicle, and a readiness criteria specifying an expected maximum time to transition the vehicle from an idle state that is not in use to an active state that is in use;
determining an action that satisfies the readiness criteria and protects the vehicle from a forthcoming environmental condition indicated by the environmental data, wherein determining the action is based on the environmental data, the capability data, and the readiness criteria; and
outputting a control signal, to an actuator, that controls the actuator to mechanically orient part of the vehicle and/or part of a structure in which the vehicle is located to at least partly implement the action.

US Pat. No. 10,507,900

COMPOSITE MATERIALS

CYTEC TECHNOLOGY CORP., ...

1. A curable composite material comprising:i) at least one structural layer of reinforcing fibres impregnated with a curable resin matrix; and
ii) at least one electrically conductive composite particle adjacent or in proximity to said reinforcing fibres, wherein said conductive composite particle is formed from a blend of a conductive material and a polymeric material, and the polymeric material in the conductive composite particle comprises one or more thermoplastic polymers that are initially in a solid phase and substantially insoluble in the curable resin matrix prior to curing of the composite material, but is able to undergo at least partial phase transition to a fluid phase by dissolving in the resin matrix during a curing cycle of the composite material, and wherein the one or more thermoplastic polymers has/have a glass transition temperature (Tg) of greater than 200° C.

US Pat. No. 10,507,889

MULTI AXIS SUSPENSION VESSEL

1. A marine vessel with a multi axis suspension system, comprising:an outer hull, said outer hull having a first mass;
an inner deck hull having a floor, said inner deck hull having a second mass;
a vertical suspension system extending above said inner deck hull, wherein said vertical suspension system is operatively connected between said inner deck hull and said outer hull so as to hold said inner deck hull in a spaced configuration above said outer hull so as to form a double hulled vessel; and
a fore and aft suspension system between said inner deck hull and said outer hull; and
wherein said second mass is greater than said first mass.

US Pat. No. 10,507,818

SHIFT CONTROL APPARATUS AND METHOD FOR VEHICLE

Hyundai Motor Company, S...

1. A shift control apparatus for a vehicle, the apparatus comprising:an engine;
a transmission configured to receive power from the engine;
a controller configured to:
check an effective sloping point based on road information;
calculate a target gear ratio based on a first engine torque at a location of the vehicle and a gear ratio of the transmission when the effective sloping point is reached within a predetermined amount of time;
set a target gear position based on the target gear ratio; and
control the transmission based on the target gear position; and
a status detector configured to detect status data for taking control of the transmission,
wherein the controller is configured to:
create a sport index based on the status data;
check a gear shift limit zone based on the sport index; and
stop shifting when the target gear position is included in the gear shift limit zone.

US Pat. No. 10,507,816

BRAKE-BY-WIRE SYSTEM

GM GLOBAL TECHNOLOGY OPER...

1. A vehicle including a fault tolerant electronic brake-by-wire (BBW) system, the vehicle comprising:a plurality of brake assemblies configured to control braking of respective wheels of the vehicle, the plurality of brake assemblies comprising a first group of brake assemblies each integrated with an electronic enhanced brake actuator assembly, and a second group of brake assemblies each integrated with an electronic enhanced smart brake actuator assembly that includes an electronic actuator controller,
wherein each enhanced smart brake actuator assembly electrically controls the brake assembly integrated therewith and at least one enhanced brake actuator assembly included in the first group of brake assemblies.

US Pat. No. 10,507,794

SYSTEM AND METHOD FOR VEHICLE CONTROL

Hyundai Motor Company, S...

1. A system for a vehicle control providing a smartkey-free starting function of a vehicle, comprising:a communicating unit including a radio frequency (RF) antenna and a low frequency (LF) antenna and configured to connect wireless communication with a user terminal which is within a predetermined sensing distance through the RF antenna;
a body controller configured to execute a door unlock according to a remote control signal of the user terminal;
a door sensor configured to sense door open and door closed signals;
a start stop button configured to generate a start on signal based on a button input; and
a controller configured to initiate a starting of the vehicle when a vehicle start condition of a state in which the user terminal is connected through the LF antenna of the communicating unit forming a communication region in the vehicle is satisfied, when the start on signal is input and the door open and door closed signals are sensed.

US Pat. No. 10,507,782

AIRBAG APPARATUS

TOYODA GOSEI CO., LTD., ...

1. An airbag apparatus comprising:a gas generator that includes
an elongated gas generator main body, which extends along an axis and discharges inflation gas, and
at least one mounting protrusion, which projects in a direction orthogonal to the axis from at least one position in a direction along the axis, and
an airbag, which is inflated by the inflation gas, wherein
the airbag apparatus is configured to be mounted to a vehicle at the at least one mounting protrusion,
the airbag includes
at least a first fabric portion and a second fabric portion, which are superposed on each other in a thickness direction, and
a storage chamber, which is located between the first fabric portion and the second fabric portion,
part of the storage chamber is constituted by the first fabric portion,
the storage chamber includes
an insertion port, which allows the gas generator to be inserted through at least the first fabric portion,
one or more mounting holes, which are located at positions that are on a leading side of the insertion port of the storage chamber in an insertion direction of the gas generator, wherein the one or more mounting holes allow the at least one mounting protrusion to be passed through at least the first fabric portion, and a rearmost one in the insertion direction of the one or more mounting holes is a rearmost mounting hole, and
an opening promoting portion, which is located between the insertion port and the rearmost mounting hole and causes the insertion port to open,
the first fabric portion and the second fabric portion are connected to each other via a folding portion and superposed on each other by being folded at the folding portion,
the insertion port is located at a position adjacent to the folding portion,
the opening promoting portion is constituted by an increased stiffness portion, which is provided in a section across the folding portion in the first fabric portion and the second fabric portion, wherein the increased stiffness portion has a higher stiffness than in regions surrounding the opening promoting portion,
a rear end of the increased stiffness portion in the insertion direction is arranged at a position adjacent to the insertion port,
the increased stiffness portion is provided over an entire region between the insertion port and the rearmost mounting hole in the insertion direction, and
part of the increased stiffness portion that is located in the first fabric portion is entirely located between the one or more mounting holes and the folding portion in a direction orthogonal to both an opening direction of the one or more mounting holes and a direction along the axis of the gas generator, which is inserted through the insertion port.

US Pat. No. 10,507,781

AIRBAG

TOYODA GOSEI CO., LTD., ...

1. An airbag comprising:a driver side portion which is stored and held in a central portion of a steering wheel for vehicular steering and has an outer peripheral wall configured to receive a driver at the time of completion of inflation; and
a steering wheel side portion which has an outer peripheral edge connected to an outer peripheral edge of the driver side portion and is supported by the steering wheel, wherein:
the steering wheel side portion is provided with an inflow opening to allow inflation gas to flow in, in the vicinity of the center, and an attaching seat which is disposed on a peripheral edge of the inflow opening and attached to the central portion of the steering wheel;
a support inflation portion protruding from a front side of the attaching seat toward a front side of the steering wheel is arranged on the steering wheel side portion at the time of completion of inflation; and
a support surface portion abutted to a front surface side of the steering wheel and supported by the central portion of the steering wheel at the time of tilting the driver side portion in a forward direction when the airbag receives a driver is arranged on a region on a rear surface side of the support inflation portion from a base portion to a tip end portion.

US Pat. No. 10,507,776

FIBER-REINFORCED COMPOSITE BUMPER BEAM AND CRUSH MEMBERS

GM GLOBAL TECHNOLOGY OPER...

1. An energy-absorbing structure for a vehicle comprising:a first component comprising a polymer and a first plurality of reinforcing fibers disposed therein, the first component comprising:
a first bumper beam portion that is at least partially defined by a first wall; and
a first crush member portion that is integrally formed with the first bumper beam portion, the first crush member portion that is at least partially defined by a second wall that projects from the first wall, and at least a first portion of the reinforcing fibers of the first plurality of reinforcing fibers continuously extending between the first wall and the second wall;
a second component comprising the polymer and a second plurality of reinforcing fibers, the second component comprising:
a second bumper beam portion that is at least partially defined by a third wall; and
a second crush member portion that is integrally formed with the second bumper beam portion, the second crush member portion that is at least partially defined by a fourth wall that projects from the third wall, and at least a second portion of the reinforcing fibers of the second plurality of reinforcing fibers continuously extending between the third wall and the fourth wall, wherein the first component is joined to the second component, and the first wall and the third wall cooperate to define a bumper beam, and the second wall and the fourth wall cooperate to define a crush member, wherein a dimension of the crush member is greatest at a location adjacent to the bumper beam.

US Pat. No. 10,507,774

COMPONENT CONFIGURATION BASED ON SENSOR DATA

Accenture Global Solution...

1. A system comprising:at least one processor; and
a memory communicatively coupled to the at least one processor, the memory storing instructions which, when executed by the at least one processor, cause the at least one processor to perform operations comprising:
receiving first sensor data describing at least one adjustment to a vehicle component that a user is using, that the user has made to improve the user's comfort in using the vehicle component;
after the user has made the adjustment to the vehicle component, receiving second sensor data that is other than data that reflects an explicit input, by the user, that the adjustment to the vehicle component failed to adequately improve the user's comfort in using the vehicle component, then automatically determining, based on the second sensor data, that the adjustment to the vehicle component likely failed to adequately improve the user's comfort in using the vehicle component;
in response to automatically determining that the adjustment to the vehicle component likely failed to adequately improve the user's comfort in using the vehicle component, providing, to a machine learning-trained model that is trained based on adjustments to similar vehicle components by other users, to output additional adjustments to the vehicle component that can be automatically made to improve users' comfort in using the vehicle component, (i) the first sensor data and (ii) data indicating a current state of the adjusted vehicle component;
receiving, from the machine learning-trained model, an additional adjustment that can be automatically made to improve the user's comfort in using the vehicle component; and
communicating the additional adjustment to the vehicle component.

US Pat. No. 10,507,768

REMOVABLE ROOF RACK SYSTEM AND REMOVABLE CROSSBAR APPARATUS FOR THAT REMOVABLE ROOF RACK SYSTEM

Ford Global Technologies,...

1. An apparatus, comprising:a crossbar having a first end and a second end;
a first slide;
a second slide;
a first releasable latch assembly connecting said first end to said first slide, said first releasable latch assembly including a first latch mechanism carried on said first end of said crossbar and a first locking pin carried on said first slide; and
a second releasable latch assembly connecting said second end to said second slide, said second releasable latch assembly including a second latch mechanism carried on said second end of said crossbar and a second locking pin carried on said second slide.

US Pat. No. 10,507,757

LUMINOUS DEVICE FOR LIGHTING THE ROAD, SIGNALLING OR INTERIOR LIGHTING

VALEO VISION, Bobigny (F...

1. A luminous device, said device comprising:a segmenting part including a plurality of through-cavities;
a plurality of light sources upstream of the segmenting part; and
a mask that blocks at least one through-cavity of the segmenting part, said mask being able to be partially passed through by light,
wherein said luminous device is arranged so that each through-cavity directly or indirectly receives light from at least one separate light source, and
wherein the mask includes at least one apertured zone and in that the mask and the segmenting part are arranged with respect to each other so that the apertured zone is placed facing at least one through-cavity.

US Pat. No. 10,507,746

VEHICLE SEAT

TS TECH CO., LTD., Saita...

1. A vehicle seat comprising:a seat back frame constituting a framework of a seat back;
a blower disposed in the seat back;
a bracket to which the blower is fixed; and
a duct connected to an inlet or an outlet of the blower,
wherein the duct has a first opening provided at one side thereof to which the blower is connected, a second opening provided at another side of the blower, and a flange provided around the first opening,
wherein the blower includes a flat surface portion around the inlet or the outlet, and
wherein the flange is disposed between the flat surface portion and the bracket and held between the flat surface portion and the bracket when the blower is fixed to the bracket.

US Pat. No. 10,507,719

FRONT END PART FOR A MOTOR VEHICLE

Dr. Ing. h.c. F. Porsche ...

1. A front-end part for a motor vehicle, comprisingan inlet opening for introduction of headwind,
an air duct adjoining the inlet opening for supplying the headwind to a radiator and to an air conditioning device,
a sound generator for outputting an acoustic signal along a sound path, and
an air-directing element for directing the headwind into the air duct, the air-directing element at least partially covering the sound generator in the sound path, and the air-direction element having a textile material that is sound-permeable for the acoustic signal of the sound generator.

US Pat. No. 10,507,711

VEHICLE VISOR EXTENSION SYSTEM

Judith J. Zabdyr, Sioux ...

1. A vehicle visor accessory device for selectively extending shading capabilities of a visor having an inboard end and an outboard end, the visor having a perimeter with an upper edge section and a lower edge section, the accessory device comprising:a main portion configured to be positioned alongside at least a portion of the visor, the main portion being elongated with an inner end for positioning adjacent to the visor and having an inner edge, the main portion having an outer end for positioning beyond the visor and having an outer edge, the main portion having a first side edge and a second side edge, the main portion having a front face and a rear face; and
a clip portion configured to pinch the visor against the rear face of the main portion, the clip portion extending outwardly from the rear face of the main portion in a manner such that the clip portion extends in a spaced and substantially parallel orientation to the rear face, the clip portion extending from the inner end of the elongated main portion in a direction toward the outer end of the elongated main portion.

US Pat. No. 10,507,708

VERTICAL SLIDING SOLUTION OF THE CONDENSER UNIT FOR TRUCKS WITH REFRIGERATED GOODS

CARRIER CORPORATION, Pal...

1. A truck comprising:an engine;
a cabin;
a conditioned space defined by a plurality of adjacent wall members including a front wall member; and
a transport refrigeration unit configured to control a temperature within the conditioned space, the transport refrigeration unit including:
an evaporator unit mounted within the conditioned space; and
a condenser unit operably coupled to the evaporator unit and slidably mounted to an exterior surface of the front wall member such that the condenser unit is configured to move between an operating position and a clearance position;
a support bracket mounted to the exterior surface and configured to define a slide axis; and
a slide member coupled to the condenser unit, the slide member being generally complementary to the support bracket and configured to slidably couple to the support bracket for movement along the slide axis.

US Pat. No. 10,507,704

AIR-CONDITIONING SYSTEM FOR VEHICLE

Hyundai Motor Company, S...

1. An air-conditioning system for a vehicle, comprising:a heating blower and a cooling blower disposed on opposite sides to face each other with an adjustment space being interposed therebetween, wherein the heating blower and the cooling blower are configured to receive air thereinto in an axial direction from the adjustment space and configured to discharge the air in a radial direction;
a first duct and a second duct configured to transfer outside air or inside air and extending in the axial direction of the heating blower and the cooling blower, wherein a first end of each of the first duct and the second duct is connected to the adjustment space to supply the outside air or the inside air to the adjustment space;
an inlet door unit disposed in the adjustment space and configured to adjust the air introduced from the first duct or the second duct to be selectively supplied to the heating blower or the cooling blower;
a condenser and an evaporation core respectively disposed in the radial directions of the heating blower and the cooling blower and connected to each other via a refrigerant line; and
an outlet door unit configured to regulate the air, which has passed through the condenser or the evaporation core, to be selectively discharged to the indoor space or the outdoor space,
wherein a direction of the air flowing through the first duct and the second duct intersects with a direction of the air ejected from the heating blower or the cooling blower.

US Pat. No. 10,507,703

STRUT MOUNT AND SUSPENSION MECHANISM USING THE SAME

SUMITOMO RIKO COMPANY LIM...

1. A strut mount comprising:a first mounting member configured to be attached to a shock absorber;
a second mounting member configured to be attached to a vehicle body;
a main rubber elastic body elastically connecting the first mounting member to the second mounting member;
a fluid-filled zone with an interior filled with a non-compressible fluid such that a vibration damping effect occurs based on a flow action of the fluid, the fluid-filled zone including a primary liquid chamber with a wall part partially defined by the main rubber elastic body and configured to fluctuate in internal pressure in response to an input of vibration to the strut mount, and an auxiliary liquid chamber with a wall part partially defined by a flexible film and configured to change volume in response to deformation of the flexible film; and
an orifice passage through which the fluid in the fluid-filled zone is induced to flow, the primary liquid chamber and the auxiliary liquid chamber being interconnected by the orifice passage, wherein:
a tuning frequency of the orifice passage is set to a frequency of a vibration transmitted during lockup of an automobile from a drive train of the automobile to the vehicle body via the shock absorber,
the fluid-filled zone is bifurcated into the primary liquid chamber and the auxiliary liquid chamber by a partition member, and a circumferential groove formed in the partition member is connected to the primary liquid chamber at a first end and to the auxiliary liquid chamber at a second end to form the orifice passage,
the main rubber elastic body includes a circular recess having an opening covered by the partition member to form the primary liquid chamber, the circular recess including (i) a pair of extended areas positioned on opposite sides of the circular recess in a vehicle front-rear direction, and (ii) a pair of constricted areas positioned on opposite sides of the circular recess in a vehicle left-right direction, the pair of extended areas having a greater depth into the main rubber elastic body than a depth of the pair of constricted areas, and the pair of extended areas being connected with each other in a circumferential direction with respect to the main rubber elastic body by the pair of constricted areas, and
a resonance frequency of the constricted areas is greater than the tuning frequency of the orifice passage.

US Pat. No. 10,507,689

CHALK LINE APPARATUS

Keson Industries, Inc., ...

1. A chalk line apparatus comprising:a housing having a body with a top, a bottom, a front, a rear, and laterally spaced sides,
the body defining an internal space within which a spool is operatively mounted;
a drive assembly that is operable through an actuator to cause flexible line to be accumulated on the spool,
the housing body having a front wall through which flexible line projecting from the spool extends to externally of the housing for use;
a fill opening on the housing through which a supply of chalk can be introduced into the internal space to contact flexible line accumulated on the spool; and
a stopper assembly that can be selectively placed in closed and open states,
the stopper assembly comprising a blocking portion that: a) blocks passage of chalk through the fill opening with the stopper assembly in the closed state; and b) permits chalk to be directed through the fill opening and into the internal space with the stopper assembly in the open state,
wherein the stopper assembly comprises a substantially flat wall from which the blocking portion projects and the housing body has a recess to receive at least a part of the substantially flat wall,
wherein the housing body has a top wall, the drive assembly actuator is connected to the housing body at the too wall at one location, and the fill opening extends through the top wall at a location spaced rearwardly from the front wall and forwardly of the one location.

US Pat. No. 10,507,688

METAL SHEET PREPARING PROCESS WITH SURFACE HAVING WOOD GRAIN AND PRODUCT THEREOF

ZHEJIANG YOTRIO GROUP CO....

1. A metal sheet with a surface having wood grain, wherein the metal sheet is manufactured by a metal sheet preparing process with surface having wood grain, the process comprising the following steps:spraying photosensitive ink on the metal sheet;
pasting a designed film on a surface of the metal sheet sprayed with the photosensitive ink;
exposing the metal sheet pasted with the film in an ultraviolet light for 1-15 min;
spray developing the surface of the metal sheet with sodium carbonate solution, and exiting the film after developing; and
etching the metal sheet exited the film after developing with a mixed aqueous solution of ferric trichloride and copper sulfate, wherein a corrosive temperature is 30-50° C. which lasts for 5-8 min; and washing corrosive liquid on the grain and cured films of the photosensitive ink out of the grain with sodium hydroxide solution of 5-8% wt %, wherein the surface having wood grain comprises the designed film and photosensitive ink; wherein the photosensitive ink is closer to the metal sheet than the designed film; wherein a maximum corrosion width is 15-20 mm, a corrosion depth is more than 0.5 mm, a gradient between a corrosion region and a non-corrosion region is more than 75°; and a pattern accuracy of the embossment when a bump of the metal sheet is 0.5-2 mm is more than 400 Dpi.

US Pat. No. 10,507,684

WRITING INSTRUMENT

MITSUBISHI PENCIL COMPANY...

1. A writing instrument comprising:an ink storage part which stores ink;
an air replacement mechanism which sends the stored ink from the ink storage part by sending air into the ink storage part; and
a central core which sucks the ink sent out by the air replacement mechanism with a capillary force, sends the sucked ink from a tip located in the central core, and makes the sucked ink adhere to a paper surface, wherein
a rate of change is 10% or smaller between widths of lines before writing and after writing at the time when the lines are written alternately and repeatedly with a writing weight of 50 g and a writing weight of 200 g.

US Pat. No. 10,507,659

LIQUID JETTING HEAD AND INK-JET PRINTER

Brother Kogyo Kabushiki K...

1. A liquid jetting head comprising:a nozzle plate having a nozzle surface in which nozzles are open;
a channel member having a first surface and a second surface on an opposite side to the first surface, the nozzle plate being joined to the first surface, the channel member being formed with channels communicating with the nozzles respectively and a cavity being different from the channels, the channels including pressure chambers respectively;
drive elements provided on the second surface of the channel member to correspond to the pressure chambers respectively, the drive elements having terminals led out to the second surface of the channel member; and
a wiring member having wirings, the wirings being joined to the terminals respectively on the second surface of the channel member,
wherein the nozzles are aligned in a first direction along the nozzle surface,
the pressure chambers are aligned in the first direction,
connecting points of the wirings and the terminals are aligned in the first direction,
at least a part of the cavity is positioned between the pressure chambers and the connecting points, in relation to a second direction which is along the nozzle surface and orthogonal to the first direction, and
the cavity has a length, in a third direction orthogonal to the nozzle surface, which is half or more of a thickness of the channel member in the third direction.

US Pat. No. 10,507,654

PRINT ELEMENT SUBSTRATE AND LIQUID EJECTION HEAD

CANON KABUSHIKI KAISHA, ...

1. A liquid ejection head comprising arrayed substrates provided with:a plurality of ejection ports provided for a plate member,
a plurality of energy-generating elements, each provided facing a corresponding ejection port and generating energy for use in ejecting a liquid from the corresponding ejection port,
a plurality of first walls, each connected with the plate member and forming a part of a channel, through which a liquid flows, provided on a side of the plurality of energy-generating elements, and
a plurality of second walls, each having a volume larger than that of the plurality of first walls and being provided on another side of the plurality of energy-generating elements,
wherein a plurality of energy-generating element rows, in which at least one of the plurality of energy-generating elements is provided with a first wall in a first direction and a second wall in a second direction opposite to the first direction and at least one of the plurality of energy-generating elements in which a second wall is provided in the first direction and a first wall is provided in the second direction are arrayed, are equipped in parallel with each other at a predetermined period;
wherein the plurality of energy-generating element rows are provided, shifted in a direction in which the plurality of energy-generating elements are arrayed in a deviation by a space or less between adjacent energy-generating elements in an energy-generating element row; and
wherein supply ports for supplying liquid to the plurality of energy-generating elements are provided on both sides of each of the plurality of energy-generating element rows.

US Pat. No. 10,507,653

LARGE FORMAT PRINTER

Seiko Epson Corporation, ...

1. A large format printer capable of serial printing on a medium which is greater than or equal to A3 short side width, comprising:a control circuit which is provided with a drive signal generating circuit which outputs a first drive signal including a first waveform, a second drive signal including a second waveform, and a reference voltage signal;
a print head which includes a plurality of drive elements which perform printing according to applied voltages; and
a cable which connects the control circuit to the print head,
wherein the print head includes a head drive circuit which applies voltages corresponding to waveforms which are selected from the first waveform in the first drive signal and the second waveform in the second drive signal which are input via the cable, to the drive elements,
wherein the cable includes, in an overlapping state, a first cable and a second cable which each include a first wire which propagates the first drive signal, a second wire which propagates the second drive signal, and a third wire which propagates the reference voltage signal, and
wherein in the first cable and the second cable, the first wire is adjacent to the third wire, the second wire is adjacent to the third wire, and, in an overlapping direction, the first wire overlaps the third wire, and the second wire overlaps the third wire.

US Pat. No. 10,507,648

LIQUID EJECTING HEAD AND LIQUID EJECTING APPARATUS

Seiko Epson Corporation, ...

1. A liquid ejecting head comprising:at least one piezoelectric element driven with a drive signal;
a switch circuit which is provided on a circuit substrate and switches between supply and shut-off of the drive signal to the at least one piezoelectric element;
a pressure chamber which is filled with liquid and changes pressure inside in accordance with the drive by the at least one piezoelectric element;
at least one nozzle which ejects the liquid filling the pressure chamber, in response to a change in the pressure within the pressure chamber;
a reserve chamber which reserves the liquid to be supplied to the pressure chamber;
a housing in which at least one part of the reserve chamber is contained; and
a flow channel substrate in which at least another part of the reserve chamber is contained, wherein
the at least one piezoelectric element is provided in a sealed space defined by a plurality of members including the circuit substrate,
the reserve chamber includes a first flow channel and a second flow channel,
a first end of the first flow channel communicates with a first end of the second flow channel within the housing or the flow channel substrate,
a second end of the first flow channel communicates with a second end of the second flow channel within the housing or the flow channel substrate, and
the circuit substrate and switch circuit are provided between the first flow channel and the second flow channel.

US Pat. No. 10,507,639

MODULAR PRINTING APPARATUS FOR 3D PRINTING

3Dbotics, Inc., Dearborn...

1. A printing apparatus, comprising:a manifold shaped as a rectangular parallelepiped having three pairs of parallel faces including a bottom face and comprising
a body thereof defining a plurality of fluidic channels,
the bottom face defining a slot configured to accommodate insertion of a printing element; and
at least one face from among the three pairs of parallel faces defining a plurality of fluidic connections in fluidic communication with the fluidic channels, wherein the manifold is configured to travel along a travel axis, and the bottom face is oriented at a non-orthogonal angle relative to the travel axis, such that when a printing element is disposed in the manifold and dispenses liquid, the liquid is dispensed at the non-orthogonal angle relative to the travel axis.

US Pat. No. 10,507,638

REACTIVE ADDITIVE MANUFACTURING

Elementum 3D, Inc., Erie...

1. A method of producing an article, comprising:providing a first material in powder form;
providing a second material in powder form, the second material capable of chemically reacting with the first material to form a reaction product;
providing a diluent material, the diluent material being added to controllably reduce an extent of propagation of the chemical reaction between the first and second materials;
forming the first, second, and diluent materials into a first layer;
subjecting a portion of the first layer to energy sufficient to initiate the chemical reaction between the first and second materials to form a portion of the article, the portion of the article comprising the reaction product;
forming a second layer of the first, second, and diluent materials on the first layer; and
subjecting a portion of the second layer to the energy to form an additional portion of the article.

US Pat. No. 10,507,637

PEELING APPARATUS

DISCO CORPORATION, Tokyo...

1. A peeling apparatus for peeling off a wafer from an ingot with a peel-off layer formed therein by applying a laser beam having a wavelength that is transmittable through the ingot to the ingot while a focal point of the laser beam is being positioned at a depth equal to a thickness of the wafer to be peeled off, in the ingot, the peeling apparatus comprising:an ingot holding unit holding the ingot in a hanging state where a portion of the ingot to be peeled off as the wafer is directed downwardly;
a water container containing water therein;
an ultrasonic unit immersed in the water in the water container;
a moving unit moving the ingot holding unit vertically into a position where the ingot holding unit faces the ultrasonic unit and at least the portion of the ingot to be peeled off as the wafer is immersed in the water in the water container; and
a nozzle ejecting water to the portion of the ingot to be peeled off as the wafer thereby to promote the peeling of the wafer from the ingot.

US Pat. No. 10,507,628

VEHICLE INTERIOR COMPONENT

Shanghai Yanfeng Jinqiao ...

1. A component for a vehicle interior comprising:a structural substrate comprising a fiber panel with at least one hole and a resin-formed structure;
a cover coupled to at least one of (a) the fiber panel or (b) the resin-formed structure;
wherein the fiber panel is formed into a compression-formed component with a shape and a thickness;
wherein the resin-formed structure of the structural substrate comprises a molded feature formed in the at least one hole of the fiber panel;
wherein the structural substrate is formed with the shape provided by the compression-formed component and with the resin-formed structure providing the molded feature in the at least one hole of the fiber panel providing the compression-formed component.

US Pat. No. 10,507,610

SOFT WRAP SUBSTRATE

1. A molded component comprising:a single injection molded polymer substrate for a motor vehicle, said single injection molded polymer substrate having a front panel with a thickness t1, a side panel with a thickness t2 and extending from said front panel at an angle, a bottom panel extending from said front panel and said side panel, wherein said front panel, side panel and bottom panel are molded together as said single injection molded polymer substrate, a first corner between and adjoining said front panel and said side panel, a second corner between and adjoining said bottom panel and said side panel, and a third corner between and adjoining said first corner and said second corner, said first corner having an effective thickness greater than thickness t1 and thickness t2; and
a groove extending along said first corner between said front panel and said side panel, said groove also extending along said second corner and said third corner, said groove extending along said first corner having a front panel edge and a side panel edge with at least one of said front panel edge and said side panel edge having alternating and repeating blocks of spaces, said alternating and repeating blocks of spaces reducing said effective thickness of said first corner and providing controlled cooling of said first corner during injection molding of said single injection molded polymer substrate;
wherein the alternating and repeating blocks of spaces form a dentil profile edge that extends into the groove whereby the groove has an increased width at each block of space in a repeating fashion;
wherein widths of the repeating blocks of spaces gradually decrease along a length of the groove forming the dentil profile edge that is curved along the length of the groove.

US Pat. No. 10,507,606

MOLD AND PROCESS FOR PRODUCING POROUS DEVICES

Vertera, Inc., Atlanta, ...

1. A method for processing material using a mold, the method comprising:loading a solid body of thermoplastic material and a layer of porogen into a non-through void in a mold via an opening of an outer mold body, the outer mold body comprising one or more pegs;
heating the mold to a processing temperature that is below a melting temperature of the thermoplastic material; and
applying a constant pressure to the solid body of thermoplastic material using a static weight of the mold to displace the layer of porogen through a surface of the solid body of thermoplastic material by a defined distance thereby creating a matrix layer including the thermoplastic material and the porogen, the static weight comprising one or more holes corresponding to the one or more pegs, wherein the static weight is received by the outer mold body via the one or more pegs.

US Pat. No. 10,507,603

METHOD FOR REINFORCING A BASE STRUCTURE

9T Labs AG, Zurich (CH)

1. A method for reinforcing an existing base structure with at least one reinforcing structure so as to form a support structure comprising the following steps:producing the at least one reinforcing structure,
connecting the at least one reinforcing structure to the base structure such that the at least one reinforcing structure is connected to the base structure in a connection position and with a connection length such that at least 50% of the length of the at least one reinforcing structure is connected with the base structure wherein and the base structure together with the at least one reinforcing structure forms the support structure,
wherein the at least one reinforcing structure, is made of a composite material comprising fibers and a matrix by means of pultrusion and/or extrusion, and a pultrusion unit and/or an extrusion unit is disposed such that the at least one reinforcing structure is pultruded and/or extruded onto the base structure at a respective required connection position after the pultrusion and/or extrusion; and
wherein before a laying of the at least one reinforcing structure onto the surface of the base structure locally in a region of a later contact area between the at least one reinforcing structure and the base structure, a material of the base structure is removed.

US Pat. No. 10,507,578

OPTIMIZATION OF OBSERVER ROBOT LOCATIONS

X Development LLC, Mount...

1. A computer-implemented method comprising:determining that an observer robot that is configured to track a particular robot using a sensor is to be moved to a new location within a worksite;
identifying multiple candidate locations within the worksite where the sensor's view of the particular robot will remain unoccluded if the observer robot is moved;
selecting, from among the multiple candidate locations within the worksite where the sensor's view of the particular robot will remain in unoccluded if the observer robot is moved, a particular location within the worksite where (i) the sensor's view of the particular robot remains unoccluded and (ii) the sensor of the observer robot is able to measure a position of the particular robot with at least a minimum degree of precision in relation to the particular robot's true position; and
transmitting data to move the observer robot to the particular location within the worksite.

US Pat. No. 10,507,560

APPARATUS MOVABLE BY A COORDINATE MEASURING MACHINE FOR POSITIONING A MEASURING INSTRUMENT WITH RESPECT TO A WORKPIECE

Carl Zeiss Industrielle M...

1. A positioning apparatus for positioning a measuring instrument relative to a workpiece, the positioning apparatus comprising:a first coupling configured to secure the positioning apparatus to a movement device of a coordinate measuring machine;
a second coupling configured to secure the measuring instrument to the positioning apparatus;
a drive configured to produce a relative movement between two parts of the positioning apparatus;
an inhibiting device configured to inhibit the relative movement between the two parts, the inhibiting device including a first friction element and a second friction element, each of the first and second friction elements having an unlubricated friction surface;
the friction surfaces being pressed against one another with a normal force, the normal force being constant during an operation of the positioning apparatus; and
a coefficient of sliding friction acting between the friction surfaces in the case of dryness and without lubrication being less than 0.15.

US Pat. No. 10,507,557

ACCESSORY FOR A HAND-HELD POWER TOOL

Robert Bosch GmbH, Stutt...

1. An accessory for a hand-held power tool, comprising:a first air channel, in which a first air stream for transporting dust particles is routed into a dust-collecting box, the first air channel having a first end adjacent to a drill bit such that the first end directly receives dust particles exiting from a drill hole formed by the drill bit; and
a second air channel, in which a second air stream for transporting dust particles is routed into one of the dust-collecting box and a further dust-collecting box, the second air channel being partially defined by a hollow portion of the drill bit.

US Pat. No. 10,507,550

EVALUATION SYSTEM FOR WORK REGION OF VEHICLE BODY COMPONENT AND EVALUATION METHOD FOR THE WORK REGION

TOYOTA SHATAI KABUSHIKI K...

1. An evaluation apparatus for a work region of a vehicle body component, the evaluation apparatus comprising:circuitry configured to:
convert a three-dimensional image of the vehicle body component to three-dimensional image data,
extract the work region of the vehicle body component in the three-dimensional image data,
extract a reference region of the vehicle body component in the three-dimensional image data,
extract a work region of the vehicle body component in three-dimensional design data used in designing the vehicle body component,
extract a reference region of the vehicle body component in the three-dimensional design data used in designing the vehicle body component,
align the three-dimensional image data with the three-dimensional design data using the reference region in the three-dimensional image data and the reference region in the three-dimensional design data, and
evaluate the work region of the vehicle body component based upon a distance between the work region in the aligned three-dimensional image data and the work region in three-dimensional design data, wherein
each of the work regions of the vehicle body component is a region for forming a spot of spot welding, and
each of the reference regions of the vehicle body component is a region where an opening hole is formed.

US Pat. No. 10,507,547

DEVICE FOR INDUCTIVE HEATING OF A COMPONENT

MTU Aero Engines AG, Mun...

1. An induction device for inductive heating of a component, comprising:a component placement unit for the component;
an induction coil, with which the component can be heated inductively, at least in regions;
an electrical lead for the induction coil; and
a positioning unit, at which the induction coil is arranged in such a way that it can be brought into different relative arrangements by the positioning unit with respect to the component placement unit;
wherein the electrical lead is guided over a contact, which is formed by contact surfaces that rest against each other and are shifted in position in relation to each other in a contact position when the induction coil is shifted in position by means of the positioning unit.

US Pat. No. 10,507,540

TOOL FOR MACHINING WELLS IN MULTI-STAGE DISCS BY PECM, ELECTROCHEMICAL MACHINING ASSEMBLY AND MACHINE INCLUDING SAID TOOL, AND METHOD USING SAID TOOL

SAFRAN AIRCRAFT ENGINES, ...

1. Tooling for making slots in a multistage disk by electrochemical machining, wherein the tooling comprises at least a first ring and a second ring, each arranged coaxially about an axis of the disk, and configured to act as a cathode for machining a respective one of two stages of different diameters of the disk, each ring having an inside periphery with a plurality of radial machining projections, the first and second rings being rigidly secured to each other.

US Pat. No. 10,507,537

METHOD OF OPERATING A POWER TOOL WITH A PROTECTED COUPLING PLATE

Robert Bosch Tool Corpora...

1. A method of mounting a capacitive coupling plate to a power tool assembly including a drop arm assembly, an actuating device configured to transfer a force to the drop arm assembly, and a control system configured to control the actuating device, comprising:connecting a capacitive coupling plate bracket formed from a non-conductive material to a drop arm frame of the drop arm assembly; and
mounting the capacitive coupling plate to the capacitive coupling plate bracket.

US Pat. No. 10,507,536

CUTTING INSERT, CUTTING TOOL, AND METHOD OF PRODUCING MACHINED PRODUCT USING THE SAME

KYOCERA CORPORATION, Tok...

1. A cutting insert, comprising:a first surface that includes:
a first corner;
a first region located along the first corner;
a second region located more inward than the first region and inclined to the first region; and
a boundary of the first region and the second region that includes a first part located on a bisector of the first corner and second parts located at both sides of the first part in a front view of the first surface;
a second surface located opposite to the first surface;
a central axis passing through a center of the first surface and the second surface; and
an imaginary plane perpendicular to the central axis and located closer to the second surface than the first surface,
wherein the second parts of the boundary are higher than the first part of the boundary with respect to the imaginary plane.

US Pat. No. 10,507,533

DRILL

KENNAMETAL INC., Latrobe...

1. A drill comprising:a nominal radius (r0);
a base body, which extends in the axial direction along an axis of rotation and rotates about the axis of rotation in a direction of rotation during operation;
flutes, which are incorporated into the base body;
a rear surface between consecutive flutes, which rear surface extends, in relation to the direction of rotation, from a leading flute to a trailing flute;
a guide chamfer formed on the rear surface in the region of the leading flute as well as a support chamfer spaced apart from it in the direction opposite the direction of rotation, wherein the support chamfer, as radially outermost region, forms a support edge with point-shaped contact to the nominal radius for a merely linear support which extends in the axial direction.

US Pat. No. 10,507,532

CHUCK FOR A HIGH PRECISION MACHINE TOOL

WIELANDTS UPMT, Nandrin ...

1. A chuck for a machine tool having a rotation spindle with a main axis of rotation, the chuck being arranged for positioning an object, at a relevant position with respect to the main axis of rotation, the chuck being arranged such that the chuck together with the object positioned on it has a principal axis of inertia that can be arranged to coincide with the main axis of rotation, the chuck comprising:a base plate comprising mounting means for mounting the chuck to the spindle;
a first rotatable plate eccentrically mounted on the base plate with respect to the main axis of rotation and having a first rotation axis running in parallel to the main axis of rotation such that the first rotational axis is shifted with respect to the main axis of rotation of the spindle;
balancing means arranged for balancing the centre of gravity of the chuck together with the object positioned on it with respect to the main axis of rotation such that the principal axis of inertia of the chuck together with the object substantially coincides with the main axis of rotation of the spindle;
a holding mechanism arranged for securing the first rotatable plate to the base plate; and
an actuating mechanism arranged for angularly displacing the first rotatable plate around the first rotation axis over a first angle of rotation such the position of the object with respect to the main axis of rotation can be altered;
wherein the chuck comprises a second rotatable plate arranged for receiving the object, the second rotatable plate being eccentrically mounted on the first rotatable plate with respect to the first rotational axis and having a second rotation axis running in parallel to the main axis of rotation and the first axis of rotation such that the second rotation axis is shifted with respect to the first rotation axis, and being secured on the first plate by means of the holding mechanism;
and wherein the actuating mechanism is arranged for angularly displacing the second rotatable plate around the second rotation axis over a second angle of rotation such that the position of the object with respect to the main axis of rotation can be altered.

US Pat. No. 10,507,521

MOULD FOR CASTING A MONOCRYSTALLINE COMPONENT

ROLLS-ROYCE plc, London ...

1. A mould for casting a component in a directional solidification casting process having off-axial dendrites having a preferred direction of dendritic growth <001> which is inclined to a longitudinal direction Y of the mould and axial dendrites having a secondary direction of dendritic growth <001> different from the off-axial dendrites, the mould comprising:a shell defining a cavity for receiving molten material, the cavity defining a three dimensional shape made up of a finished component geometry portion and a sacrificial geometry portion,
wherein the sacrificial geometry portion includes a base wall and a notch configured to contain axial dendritic growth in the secondary direction of dendritic growth <001> within the sacrificial geometry portion of a casting solidifying in the mould, and
the notch has an apex A in the sacrificial geometry portion disposed at a position from the base wall in the longitudinal direction Y corresponding to a maximum acceptable distance L up to which it is acceptable for the axial dendrites to overgrow the off-axial dendrites in the secondary direction of dendritic growth <001>.

US Pat. No. 10,507,515

CERAMIC CORE FOR COMPONENT CASTING

United Technologies Corpo...

17. A method for casting a component comprising:casting a first material around a casting ceramic core, wherein the casting ceramic core is a fiber reinforced ceramic core including a plurality of through holes and at least one thin wall defining a boundary between a first through hole in the plurality of through holes and a second through hole in the plurality of through holes, the casting ceramic core including also a plurality of aligned fibers extending a substantial length of at least one casting feature, and at least one through hole of the plurality of through holes displaces a longitudinal alignment of fibers in the plurality of aligned fibers; and
destroying the casting ceramic core, thereby leaving a void defined within the cast material.

US Pat. No. 10,507,509

PIPE EXPANDING DEVICE WITH A PIPE-LENGTH FIXING ASSEMBLY

Yung Chi Industry Co., Lt...

1. A pipe expanding device with a pipe-length fixing assembly, suitable for holding a pipe with a connecting end, and comprising:a body including a first space and a second space;
a clamping unit detachably disposed in the first space, and the clamping unit being provided for the pipe to be inserted therein, wherein the connecting end of the pipe is able to move back and forth within the second space; and
the pipe-length fixing assembly being disposed in the second space and able to move back and forth toward the first space, and the connecting end of the pipe is stopped against the pipe-length fixing assembly; and
a drive unit mounted on the body for expanding the pipe;
wherein the first and second spaces are connected to each other, the second space is defined by a lateral portion and an opposite lateral working portion, an adjustment hole is formed in the lateral working portion and extends in a moving direction of the pipe, and the pipe-length fixing assembly is disposed in the adjustment hole of the second space and able to move back and forth repeatedly;
the pipe-length fixing assembly includes a positioning unit and an adjustment unit, the positioning unit includes a positioning head disposed in the second space and abutted against an inner surface of the lateral working portion, and a positioning body disposed in the adjustment hole, and the adjustment unit includes an adjustment head abutted against an outer surface of the lateral working portion, and an adjustment body adjustably disposed on the positioning body.

US Pat. No. 10,507,506

HYDRAULIC DRAWING CUSHION OF A DRAWING PRESS AND METHOD OF OPERATING THE HYDRAULIC CUSHION

Schuler Pressen Gmbh, Go...

1. A drawing press (10), comprising:a floating plate (18) configured to move in a work direction,
a drawing cushion (17) comprising:
a hydraulic cylinder (21) comprising a cylinder housing (25) and a piston (26) with a piston rod (27), wherein the piston rod is configured to drive the floating plate (18),
a plurality of hydraulic work chambers (29, 30) including a first work chamber, a second work chamber, and a third work chamber provided in the cylinder housing (25),
a spring device (45) configured as a fluidic spring device (45a) and configured to apply an essentially constant spring force (F) to the piston (26) during operation of the drawing press (10),
a first piston area (31) is adjacent to the first work chamber (29), and a second piston area (32) is adjacent to the second work chamber, and wherein the first work chamber (29) and the second work chamber (30) are connected to a hydraulic pump (40) of a hydraulic work circuit (37),
wherein the fluidic spring device (45a) comprises a pressure storage (50) that is connected to the third work chamber (47) of the cylinder (21) via a pressure line (49), wherein the third work chamber (47) is adjacent to a third piston area (48) of the piston (26).

US Pat. No. 10,507,504

HYBRID EXTRUSION PRESS

Ube Machinery Corporation...

1. A hybrid extrusion press comprising:a machine base,
an end platen having a die,
a main crosshead having an extrusion stem and sliding on the machine base,
a hydraulic main ram coupled with the main crosshead,
a container holder sliding on the machine base,
electric motors and hydraulic assist cylinders that cause the container holder to slide, and
connecting rods fastened to the container holder, wherein
the hydraulic assist cylinders have piston rods and gate devices connecting or disconnecting the connecting rods and the piston rods, and
the gate devices are provided with hollow members fastened to the piston rods, enlarged diameter parts provided at single ends of the connecting rods and moving back and forth inside hollow parts of the hollow members, and locking parts provided at the hollow members and locking the enlarged diameter parts.

US Pat. No. 10,507,484

PUMP APPARATUS AND SUBSTRATE TREATING APPARATUS

SCREEN Holdings Co., Ltd....

1. A pump apparatus for supplying a processing liquid, the pump apparatus comprising:a filter inserted into a processing liquid flow path through which the processing liquid flows;
an upstream pump disposed upstream of the filter and inserted into the processing liquid flow path;
a downstream pump disposed downstream of the filter and inserted into the processing liquid flow path, the downstream pump having an inlet higher in level than an outlet of the upstream pump and higher in level than an outlet of the filter; and
a return flow path connected between the downstream pump and the upstream pump for returning the processing liquid from a return outlet of the downstream pump to a return inlet of the upstream pump,
the outlet of the upstream pump being disposed higher in level than an inlet of the upstream pump and the return inlet of the upstream pump,
the return inlet of the upstream pump being disposed at the same level as or higher in level than the inlet of the upstream pump,
the return outlet of the downstream pump being disposed higher in level than a supply outlet of the downstream pump.

US Pat. No. 10,507,482

CONTAINER FOR DISCHARGING POWDER

YONWOO CO., LTD., Incheo...

1. A container for discharging powder, comprising:a container body storing powder;
a button part rotatably disposed at an upper portion of the container body and ascending/descending according to the presence or absence of a user's pressurizing, further comprising a discharging hole, where powder is discharged, at one side thereof;
a stem which is disposed at an inner side of the button part and moves along with the movement of the button part, comprising a movement hole at an upper portion thereof such that powder can flow according to the manipulation of the button part and further comprising, at a side thereof, a connecting hole connected with the discharging hole such that the powder flowing through the movement hole can be discharged through the discharging hole;
a content movement part which is disposed at an inner side of the stem, separately forming a powder moving passage where powder flows and an air moving passage where air flows; and
an opening/closing member, which is inserted into an upper portion of the stem, ascending and opening the movement hole when the button part rotates to one side direction and closing the movement hole when the button part rotates to the other side direction,
wherein the discharging hole of the button part and the connecting hole of the stem are connected to each other when the opening/closing member ascends by the rotation of the one side direction and opens the movement hole, the discharging hole of the button part and the connecting hole of the stem are disconnected from each other when the button part descends and closes the movement hole,
wherein the container for discharging powder is characterized in a way that an inner pressure of the container body changes according to pressurization of the button part, and powder and air flow into the stem respectively through the powder passageway and the air passageway to the content movement part, thereby making powder discharged and sprayed through the discharging hole by air pressure.

US Pat. No. 10,507,476

SPRINKLER WITH BRAKE ASSEMBLY

Rain Bird Corporation, A...

1. A sprinkler comprising:a frame having an upper portion, a lower portion, and at least one support member connecting the upper and lower portions;
a rotatable deflector connected to the frame upper portion for directing fluid outwardly from the sprinkler;
a socket of the frame lower portion;
a nozzle configured to be releasably connected to the socket and having an outlet configured to direct fluid toward the deflector;
a skirt of the nozzle that extends about the socket with the nozzle connected to the socket;
at least one nozzle member of the nozzle extending toward the socket from the skirt;
at least one detent and at least one recess on upper and lower surfaces of the at least one nozzle member and the socket adapted to releasably couple the nozzle to the socket.

US Pat. No. 10,507,471

GRAVITY SEPARATION DEVICE

SUMITOMO METAL MINING CO....

1. A gravity separation device separating an overflow and an underflow using a difference in specific gravity from a slurry of laterite ore including two or more types of ore particles having different specific gravities,wherein the percentage of ore particles contained in the slurry and having a particle size of 2000 ?m or less is 100% and the percentage of ore particles contained in the slurry and having a particle size of 75 ?m or less is 70% to 90%,
the gravity separation device comprising:
a separation section that has a supply pipe for supplying the slurry of laterite ore to an upper portion and separates the slurry into an overflow and an underflow;
and
a deposition section that is positioned at the lower side of the separation section and in which the underflow separated by precipitation is deposited, wherein
a pressure meter for measuring a pressure inside the separation section is provided in the separation section,
an extraction pipe for discharging the underflow is connected to the deposition section,
a valve for discharging the underflow and a metering pump for quantitatively discharging the underflow are provided in the extraction pipe, and
the metering pump controls a discharged amount of the underflow on the basis of a measurement value obtained by the pressure meter.

US Pat. No. 10,507,466

METAL ASSISTED CHEMICAL ETCHING FOR FABRICATING HIGH ASPECT RATIO AND STRAIGHT SILICON NANOPILLAR ARRAYS FOR SORTING APPLICATIONS

INTERNATIONAL BUSINESS MA...

1. A method of forming a sorting device using metal assisted chemical etching, the method comprising:depositing a resist material on top of a substrate, the resist material having a thickness covering a top surface of the substrate;
etching the resist material into a pattern having trenches extending in a first direction and a second direction, the trenches exposing the top surface of the substrate;
depositing a metal layer on the patterned resist material and directly on the top surface of the substrate where the patterned resist material is absent, such that the metal layer is free from sidewalls of the trenches, wherein the thickness of the patterned resist material is greater than a height of portions of the metal layer directly on the top surface of the substrate;
forming a mesh of the metal layer on top of the substrate by removing the patterned resist material;
performing the metal assisted chemical etching to remove substrate material of the substrate at locations of the mesh, wherein pillars are formed in the substrate by removal of the substrate material, the pillars having a uniform size; and
removing the mesh to leave the pillars in a nanopillar array, wherein the pillars in the nanopillar array are configured with a spacing to sort particles of different sizes such that the particles at or above a predetermined dimension are sorted in a first direction to a first opening and the particles below the predetermined dimension are sorted in a second direction to a second opening, wherein performing the metal assisted chemical etching forms the pillars in the nanopillar array with a critical angle toward the first direction of the first opening and away from the second opening, the pillars being formed with about a 90 degree angle between a top and a side of the pillars.

US Pat. No. 10,507,458

HYDROTREATING CATALYST AND PROCESS FOR PREPARING THE SAME

INDIAN OIL CORPORATION LI...

1. A process for preparing a hydro treatment catalyst comprising an inorganic oxide material based carrier, a group VI B metal and a group VIII metal adsorbed to the carrier, wherein the inorganic oxide material based carrier comprises alumina matrix and a modifying element grafted to the alumina matrix, and the modifying element being present in an amount in the range of 0.01 to 2% of a total weight of the inorganic oxide material based carrier, said process comprising the steps of:a. preparing a solution comprising a modifying element additive;
b. adding alumina powder to the aforesaid solution to obtain alumina matrix comprising modifying element grafted to surface of alumina;
c. filtering the alumina matrix and washing the same to remove non-grafted modifying element additive;
d. mixing the alumina matrix with a binder to obtain a homogenous dough;
e. extruding the dough to form a solid material;
f. drying, ageing and calcining the solid material to obtain the inorganic oxide material based carrier comprising alumina matrix and the modifying element grafted to the alumina matrix; and
g. impregnating a solution of group VI B metal and a group VIII metal to the inorganic oxide material based carrier to obtain the hydro treatment catalyst;
wherein the group VI B metal is an oxide of molybdenum and the group VIII metal is an oxide of nickel or cobalt or mixture thereof;
wherein the modifying element is selected from a group consisting of boron, aluminium, silicon, titanium, cerium and mixtures thereof; and
wherein said impregnating solution is reacted with 0.01-1 moles of a suitable amine compound per mole of Mo selected from the group of compounds consisting of monoethanol amine, diethanol amine and diethyl amine.

US Pat. No. 10,507,454

PHOTOCATALYST MATERIAL AND METHOD FOR PRODUCING SAME

SHARP KABUSHIKI KAISHA, ...

1. A photocatalyst material comprising:core particles including tungsten oxide;
a promoter on a surface of the core particles; and
a shell layer including titanium oxide and covering an entire surface of both the core particles and the promoter such that no portion of the surface of the core particles is exposed to an outside and no portion of the surface of the promoter is exposed to an outside.

US Pat. No. 10,507,451

SONICATION IN A UREA OR MELAMINE SYNTHESIS PROCESS

Casale SA, (CH)

1. A process for the synthesis of melamine from urea, inside a chemical reactor, said process comprising a sonication treatment of at least part of a reaction liquid mass or two-phase mixture contained inside said chemical reactor,wherein the sonication treatment is performed in a sonication zone inside said chemical reactor,
wherein the process further comprises the circulation of a liquid phase or liquid/vapour phase through at least one reaction zone and a recirculation zone, which are arranged coaxial and concentric inside said reactor, wherein the sonication treatment is performed in at least one of said two reaction and recirculation zones, and
wherein the reaction zone is a primary reaction zone fed with urea melt.

US Pat. No. 10,507,448

METHODS FOR DESIGNING SCALED-UP FLUID CATALYTIC REACTORS

Dow Global Technologies L...

1. A method for scaling-up a fluid catalytic reactor, the method comprising:one or more of constructing, operating, observing, or obtaining data related to a template fluid catalytic reactor comprising a template riser, a template lower reactor portion, and a template transition portion connecting the template riser and the template lower reactor portion;
one or more of constructing or operating a scaled-up fluid catalytic reactor based on the template fluid catalytic reactor, the scaled-up fluid catalytic reactor comprising a scaled-up riser, a scaled-up lower reactor portion, and a scaled-up transition portion connecting the scaled-up riser and the scaled-up lower reactor portion, wherein:
the ratio of the cross-sectional area of the scaled-up riser to the cross-sectional area of the template riser is from 80% to 120% of a scale-up factor;
the ratio of the cross-sectional area of the scaled-up lower reactor portion to the cross-sectional area of the template lower reactor portion is from 80% to 120% of the scale-up factor;
the scale-up factor is at least 1.3; and
the height of the scaled-up transition portion is at least 70% of the width of the scaled-up riser and from 70% to 130% of the height of the template transition portion.

US Pat. No. 10,507,430

HOLLOW FIBER MEMBRANE SHEET-LIKE OBJECT, METHOD OF MANUFACTURING HOLLOW FIBER MEMBRANE SHEET-LIKE OBJECT, HOLLOW FIBER MEMBRANE SHEET LAMINATE, METHOD OF MANUFACTURING HOLLOW FIBER MEMBRANE SHEET LAMINATE, HOLLOW FIBER MEMBRANE MODULE AND METHOD OF MANUFA

Mitsubishi Chemical Corpo...

1. A hollow fiber membrane module comprisingat least one hollow fiber membrane sheet-like object in which a plurality of hollow fiber membranes is aligned in parallel with each other and fixed to each other while both end faces of each of the hollow fiber membranes in a longitudinal direction are open,
wherein at least one belt-like binding portion made of an elastic body having an elongation percentage (E) stipulated by JIS K6251 of 100% or more and extending in a direction perpendicular to the longitudinal direction is formed at each of both end portions of the hollow fiber membrane sheet-like object, and the plurality of hollow fiber membranes is fixed to each other and
a pair of elongated housings in which openings are formed along a longitudinal direction, both ends of the hollow fiber membrane sheet-like object being inserted into the openings and fixed,
wherein
at least two binding portions are formed at each of the two ends of the hollow fiber membrane sheet-like object, wherein at least one of said at least two binding portions is said belt-like binding portion,
the hollow fiber membrane sheet-like object is fluid-tightly fixed by resin inside each of the elongated housings while only a binding portion provided closest to an end portion side at each end portion in the binding portions formed at both ends of the hollow fiber membrane sheet-like object is inserted into each of the elongated housings, and each binding portion provided on a center side of the hollow fiber membrane sheet-like objects in the longitudinal direction in the binding portions in two rows is a portion exposed from each of the elongated housings without being inserted into either of the elongated housings, and
one of the two binding portions exposed from each of the elongated housings in each end portion is formed at a position at which a distance L from the opening of each of the elongated housings are in a range of 1 to 30 mm.

US Pat. No. 10,507,425

IONIC LIQUID CO2 SCRUBBER FOR SPACECRAFT

HONEYWELL INTERNATIONAL I...

1. A contaminant removal subsystem, comprising:a scrubber that includes a housing and a packed bed that is non-rotating relative to the housing;
wherein the scrubber is configured to receive a contaminated air and a clean liquid absorbent, and discharge a cleaned air and a used liquid absorbent;
wherein the cleaned air contains a lower concentration of gas contaminant than the contaminated air;
wherein the used liquid absorbent includes gas contaminant absorbed into clean liquid absorbent;
a stripper downstream, with respect to used liquid absorbent, of the scrubber;
wherein the stripper is configured to desorb gas contaminant from the used liquid absorbent to produce a regenerated liquid absorbent;
a heat exchanger between the scrubber and the stripper; and
a heater directly downstream, with respect to used liquid absorbent, of the heat exchanger and directly upstream, with respect to used liquid absorbent, of the stripper, wherein the heater is configured to heat used liquid absorbent without employing another heater for heat exchange.

US Pat. No. 10,507,408

SUPERFICIALLY POROUS PARTICLES WITH PRECISELY CONTROLLED PARTICLE DENSITY, AND METHODS OF PREPARATION AND USE THEREOF

AGILENT TECHNOLOGIES, INC...

1. A plurality of superficially porous particles, each comprising:a hollow core;
a non-porous inner shell; and
a substantially porous outer shell, wherein
the hollow core has a radius ranging from about 20% to about 90% of the radius of the entire particle;
the particles have a median size range from about 0.5 ?m to about 100 ?m with a particle size distribution (one standard deviation) of no more than 15% of the median particle size; the particles have a specific surface area of from about 5 m2/g to about 1,000 m2/g; and
the particles comprise a metal oxide selected from silica, alumina, titania or zirconia.

US Pat. No. 10,507,398

SHOOTING-TYPE TOY

CHOIROCK CONTENTS FACTORY...

1. A shooting toy comprising:a body having a plurality of members;
a latch part (150, 150a, 150e) for locking the body thereonto to allow the body to be kept to a first form; and
a projectile (200, 200a, 200b, 200c) moving from the outside in such a manner as to be inserted into the body and thus located in a shooting part (130, 130e) disposed in the body,
wherein the projectile (200, 200a, 200b, 200c) releases a locking state of the latch part (150, 150a, 150e) to allow the body to be developed to a second form, and
wherein in response to the projectile located in the shooting part, the projectile is shot from the body developed to the second form by means of a pressurizing part disposed in the body.

US Pat. No. 10,507,396

AMUSEMENT DEVICE FOR ASCENDING, BACKWARDS RUSHING AND FALLING

GOLDEN HORSE TECHNOLOGY E...

1. An amusement device for ascending, backwards rushing and falling, comprising:a lifting tower, the lower part of the lifting tower being provided with an entry section, the upper part of the lifting tower being provided with a lifting slide-out section, an amusement ship entering the lifting tower by the bow through the entry section and then leaving the lifting tower by the stern through the lifting slide-out section to return in the same direction, and the entry section and the lifting slide-out section being in the same direction;
and a descending tower, the upper part of the descending tower being provided with a descending entry section, the lower part of the descending tower being provided with a descending slide-out section, the amusement ship entering the descending tower through the descending entry section and then leaving the descending tower through the descending slide-out section to return in the same direction, and the descending entry section and the descending slide-out section being in the same direction,
wherein the lifting slide-out section comprises a backwards-rushing frame connected with the upper end of the lifting tower, and the backwards-rushing frame is provided with a backwards-rushing guide rail/backwards-rushing guide rails.

US Pat. No. 10,507,395

HABITABLE SUPPORT STRUCTURE FOR OBSERVATION WHEELS

1. A system comprising:a tower comprising:
an enclosure defining an interior volume; and
a plurality of vertical walls and a plurality of horizontal floors disposed within the interior volume;
wherein the walls and the floors are coupled in fixed relation to the enclosure such that the walls and floors define a plurality of human-habitable spaces within the interior volume;
a tower hub coupled to the tower and having:
a transverse dimension of at least 50 feet; and
a shell that defines an interior space and has one or more horizontal floors coupled to the shell, wherein:
at least a portion of each of the floor(s) of the shell is disposed within the interior space; and
the interior space is accessible from the tower; and
an observation wheel having a central wheel hub and rotatably coupled to the tower such that the wheel hub is configured to rotate around the tower hub.

US Pat. No. 10,507,383

INFORMATION PROCESSING METHOD AND APPARATUS, ELECTRONIC DEVICE, AND STORAGE MEDIUM

NETEASE (HANGZHOU) NETWOR...

1. An information processing method, applied to a mobile terminal having at least one processor for executing a software application and a touch screen which is rendered with a graphical user interface, contents rendered on the graphical user interface comprising a game scene, a virtual character and at least one signal icon, the method comprising:providing a touch area on the graphical user interface, and configuring the virtual character to move in the game scene according to a first touch operation in the touch area;
when a second touch operation of which a starting touch point is in the at least one signal icon is detected, detecting a position of a current touch point of the second touch operation in real time;
when the position of the current touch point satisfies a preset condition, providing a mini-map on the graphical user interface; and
when the end of the second touch operation is detected, and a position of an ending touch point of the second touch operation is in the mini-map, sending a prompt signal corresponding to the at least one signal icon, the prompt signal comprising position indication information of the game scene.

US Pat. No. 10,507,377

SPORTS WALL ASSEMBLY

1. A wall assembly, comprising:a support assembly;
a vertically extending transparent shield fixedly attached to an upper end of the support assembly;
a movable wall assembly;
a plurality of shock absorbers positioned between the support assembly and the movable wall assembly, each of the plurality of shock absorbers stores energy when a force is exerted upon the movable wall assembly by an object such that the movable wall assembly moves from a first position to one of a plurality of second positions to cause deceleration of the object over a distance, and the plurality of shock absorbers move the movable wall assembly from the one of the plurality of second positions to the first position by releasing energy when the force is removed.

US Pat. No. 10,507,365

GOLF CLUB HEAD

Taylor Made Golf Company,...

1. A golf club head comprising:a body having a bottom portion, a top portion, a front portion, a back portion, a heel portion, and a toe portion;
a sole located on the bottom portion of the golf club head;
a face positioned at the front portion of the body, the face being configured to receive an impact;
a top portion silhouette profile located along a perimeter of the top portion, the top portion silhouette profile defining outer bounds of the top portion in an X-direction and Y-direction, the golf club head having a bottom portion volume below the top portion silhouette profile and a top portion volume above the top portion silhouette profile;
a center sole portion extending from the front portion of the body to the back portion of the body, the center sole portion comprising:
a planar surface extending rearwardly along the bottom portion of the golf club head in a generally Y-direction;
a toeward sole surface that slopes upwardly from the planar surface when viewed in an address position;
a first edge extending in a generally Y-direction on a toe side of the planar surface and defining a transition between the planar surface and the toeward sole surface;
a heelward sole surface that slopes upwardly from the planar surface when viewed in the address position; and
a second edge extending in a generally Y-direction on a heel side of the planar surface and defining a transition between the planar surface and the heelward sole surface;
wherein the golf club head has a head origin defined as a position on a face plane at a geometric center of the face, the head origin including an x-axis tangential to the face and generally parallel to a ground plane when the head is in the address position where a positive x-axis extends towards the heel portion, a y-axis extending perpendicular to the x-axis and generally parallel to the ground plane when the head is in the address position where a positive y-axis extends from the face and through a rearward portion of the body, and a z-axis extending perpendicular to the ground plane, to the x-axis and to the y-axis when the head is in the address position where a positive z-axis extends from the head origin and generally upward,
wherein the golf club head has a center of gravity with an x-axis coordinate between about ?2 mm and about 7 mm, a y-axis coordinate between about 15 mm and about 50 mm, and a z-axis coordinate between about ?7 mm and about 2 mm,
wherein a heel-toe dimension of the golf club head is between about 119 mm and about 127 mm,
wherein a top-bottom dimension of the golf club head is between about 63 mm and about 71 mm, and
wherein the bottom portion volume is greater than 60 percent of a total volume of the golf club head.

US Pat. No. 10,507,364

GOLF CLUBS AND GOLF CLUB HEADS

Karsten Manufacturing Cor...

1. A golf club head, comprising:a club head body having an overall club head length dimension of at least 4.6 inches and an overall club head breadth dimension of more than 4.5 inches, wherein:
a ratio of the overall club head breadth dimension to the overall club head length dimension is at least 0.94 and is less than 1;
the club head body includes a hosel member for receiving a shaft; and
the club head body further has a center of gravity, a hosel center axis, and a Delta Z dimension within a range of 2.5 to 4 inches, wherein the Delta Z dimension is a distance, measured parallel to the hosel center axis, between the center of gravity and a plane tangent to a top rim of the hosel member.

US Pat. No. 10,507,349

EXERCISE FRAME SYSTEM

1. A frame system consisting of:a) a plurality of tubes formed to predetermined lengths for constructing a frame;
b) a plurality of connectors for attaching tubes together to hold the frame together or attach accessories to the frame: and
c) a plurality of locking pins, the locking pins comprising at least three flat longitudinal sides and a length which enters a matching flat sided hole on one side of the tube or a tube connector and out a matching flat sided hole on the opposite side of the tube or a tube connector and is held in place by a cap on one end of the pin and one or more flexible nubs on the other end of the pin extending radially outward from one of the flat longitudinal sides, and positioned entirely on the surface of said flat longitudinal side of the locking pin, the nub and cap positioned to be outside the tube or a tube connector.

US Pat. No. 10,507,339

IMAGING BASED CALIBRATION SYSTEMS, DEVICES, AND METHODS

VARIAN MEDICAL SYSTEMS, I...

1. A method for automatically positioning a target at an isocenter for each gantry angle, comprising:generating images of the target at a plurality of gantry angles;
determining a target location for each gantry angle from the generated images;
for each gantry angle, determining a target location offset by comparing a generated image for a gantry angle with a corresponding reference image; and
correcting the target location offset for each gantry angle by:
moving the target to the isocenter; and
repositioning the target location by moving the target by a distance which equals a previously determined couch rotation dependent offset value.

US Pat. No. 10,507,338

PARTICLE BEAM RADIOTHERAPY SYSTEM

Canon Medical Systems Cor...

1. A particle beam radiotherapy system comprising:a gantry configured to apply particle beams to a subject;
an ultrasonic diagnostic apparatus configured to scan the subject with ultrasonic waves via an ultrasonic probe, and acquire an ultrasonic image concerning a radiotherapy target region of the subject;
processing circuitry configured to
specify a first planned point of a Bragg peak in the ultrasonic image, which anatomically coincides approximately with a second planned point of the Bragg peak determined using a radiotherapy planning apparatus, the first planned point and the second planned point being positioned so as to be included in the radiotherapy target region, and
estimate a sighting point of the Bragg peak of a particle beam applied by the gantry based on information concerning a body surface position of the subject and an actual range of the particle beam applied by the gantry; and
a display configured to display the ultrasonic image so as to indicate the first planned point and the sighting point.

US Pat. No. 10,507,335

COIL ARRANGEMENT AND SYSTEM FOR TRANSCRANIAL MAGNETIC STIMULATION

EBERHARD KARLS UNIVERSITA...

1. A coil assembly comprising a housing,a magnetic coil, and
an electrode arrangement,
wherein the magnetic coil is arranged in the housing and is adapted for generating a magnetic field for transcranial magnetic stimulation,
wherein the electrode arrangement is arranged on the housing and adapted for deriving an electroencephalogram (EEG) signal, and
wherein the electrode arrangement is entirely confined within the perimeter of the magnetic coil.

US Pat. No. 10,507,331

WEARABLE CARDIAC DEFIBRILLATOR SYSTEM CONTROLLING CONDUCTIVE FLUID DEPLOYMENT

WEST AFFUM HOLDINGS CORP....

1. A wearable defibrillator system, comprising:a support structure configured to be worn by a patient;
an energy storage module configured to store a charge;
two electrodes coupled with the support structure and configured to be applied to two respective patient locations of the patient;
a reservoir coupled to the support structure and configured to store a fluid;
a fluid deploying mechanism configured to cause at least some of the fluid to be released from the reservoir and be deployed near at least one of the patient locations, so as to cause an impedance between the two electrodes to be decreased; and
an impedance measurement circuit configured to sense the decreased impedance, and
in which the stored charge is delivered to the patient via the electrodes responsive to a timeout threshold lapsing since at least some of the fluid has been caused to be released, or responsive to the sensed impedance meeting a discharge condition prior to the timeout threshold lapsing, the discharge condition being distinct from the timeout threshold lapsing, the stored charge thus being delivered to the patient responsive to the earlier of:
i) the timeout threshold lapsing, and
ii) the sensed impedance meeting the discharge condition prior to the timeout threshold lapsing.

US Pat. No. 10,507,326

METHOD AND APPARATUS FOR MULTIMODAL ELECTRICAL MODULATION OF PAIN

Stimgenics, LLC, Bloomin...

1. A method for managing pain in a subject comprising:A) lowering a threshold for depolarization of nerve fibers in the subject with a first oscillating electromagnetic field for a first duration of time; and
B) simultaneously modulating glial cell activity in the subject with a second oscillating electromagnetic field during a second duration of time not identical to the first duration of time,
wherein the first oscillating electromagnetic field is provided by an electrical signal having a current amplitude set to a value corresponding to a percentage of a Priming Perception Threshold (PPT) of the subject, and
wherein the second oscillating electromagnetic field is provided by an electrical signal having a current amplitude set to a value corresponding to a percentage of the paresthesia threshold (PT) of the subject.

US Pat. No. 10,507,325

DEVICES AND METHODS FOR NON-INVASIVE CAPACITIVE ELECTRICAL STIMULATION AND THEIR USE FOR VAGUS NERVE STIMULATION ON THE NECK OF A PATIENT

ElectroCore, Inc., Bosto...

7. An apparatus for modulating a vagus nerve within a body of a patient, the apparatus comprising:a source of energy that generates a single signal comprising an electrical impulse;
an electrode coupled to the source of energy;
an interface coupled to the electrode; and
wherein the source of energy delivers the electrical impulse, based on the single signal, from the electrode through the interface and the outer skin surface to the vagus nerve, as the interface contacts an outer skin surface of a neck of the patient, and thereby modulates the vagus nerve, wherein the electrical impulse comprises bursts of pulses with a silent intra-burst interval between each of the bursts based on the single signal, wherein each of the bursts has a frequency of about 5 Hz to about 100 Hz and each of the pulses has a duration from about 50 microseconds to about 1000 microseconds.

US Pat. No. 10,507,319

MULTIPLE FLUID DELIVERY SYSTEM WITH MULTI-USE DISPOSABLE SET AND FEATURES THEREOF

BAYER HEALTHCARE LLC, Wh...

1. A multi-use disposable set (MUDS) comprising:a plurality of syringes, each syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis, a filling port and a discharge outlet at the distal end of each of the plurality of syringes, and a plunger reciprocally movable within a syringe interior of each of the plurality of syringes between the proximal end and the distal end;
a manifold in selectable fluid communication with the discharge outlet of each of the plurality of syringes;
at least one rotatable valve in fluid communication with the distal end of at least one of the plurality of syringes, wherein the at least one rotatable valve comprises a valve head with a slot recessed into the valve head, wherein the slot has a lip at one end of the slot which limits an orientation of a blade of a coupling mechanism of a fluid injector to a single self-aligned orientation, wherein the at least one rotatable valve is rotatably operable between a filling position for filling the syringe interior of the at least one of the plurality of syringes through the filling port and a delivery position for delivering fluid from the syringe interior of the at least one of the plurality of syringes to the manifold through the discharge outlet; and
at least one connection port in fluid communication with the manifold when the at least one rotatable valve is in the delivery position,
wherein the filling port is in fluid isolation from the syringe interior when the at least one rotatable valve is in the delivery position.

US Pat. No. 10,507,317

CONNECTOR SHIELD FOR SENSOR ENABLED MEDICAL DEVICES

1. A medical device connector shield, comprising:an elongate hollow cylindrical body that extends along a longitudinal axis;
a distal cap portion that extends along the longitudinal axis, wherein a proximal end of the distal cap portion is connected to a distal end of the elongate hollow cylindrical body;
a wire management port defined in the distal cap portion; and
a wire management tube extending from the wire management port, wherein the wire management tube extends distally from the wire management port.

US Pat. No. 10,507,315

SYSTEMS AND METHODS FOR ULTRASOUND IMAGING AND INSONATION OF MICROBUBBLES

University of Virginia Pa...

1. A method of providing therapy to a treatment site of a subject, said method comprising:advancing a distal end portion of an ultrasound catheter to or in proximity to the treatment site;
dispensing microbubbles from said catheter according to a pacing protocol and in a manner that said microbubbles flow over the treatment site, wherein said dispensing according to said pacing protocol dispenses said bubbles in a timed manner relative to the cardiac cycle of the subject; and
bursting said microbubbles to dispense drug or gene therapy to the treatment site.

US Pat. No. 10,507,304

CATHETER DEVICES, KITS AND METHODS

VASCULAR BARCELONA DEVICE...

1. A catheter device configured to provide access to a hollow organ through a puncture made in a skin of a patient comprising:a body having a proximal end, a distal end and a non-cylindrical external shape and a flexible insertion tube having a proximal end and a distal end, the body including one or more external flat surfaces located between the proximal and distal ends of the body wherein:
the body comprises:
an internal elongated channel that extends along an entire length of the body between the proximal end and the distal end of the body, wherein the internal elongated channel is configured to receive a removable elongated needle, and
only first and second cutting edges extending rearwardly from the distal end of the body, the first and second cutting edges being located on opposite sides of the body and configured to act together to elongate the puncture when advanced into the puncture,
the flexible insertion tube is fixedly attached to the distal end of the body and comprises:
a tubular elongated passage aligned with the internal elongated channel of the body forming a lumen having a length.

US Pat. No. 10,507,299

RELEASABLE ELBOW CONNECTOR

Koninklijke Philips N.V.,...

1. An elbow connector for use with a patient interface device and a delivery conduit, comprising:a first coupling portion structured to be inserted into an opening in the patient interface device to couple the elbow connector with the patient interface device, the first coupling portion including an upper coupling portion and a lower coupling portion disposed opposite the upper coupling portion;
a second coupling portion structured to couple to the delivery conduit; and
an intermediate portion disposed between the first coupling portion and the second coupling portion, the intermediate portion including a rear surface,
wherein the lower coupling portion includes a first end and a second end, wherein the first end of the lower coupling portion is coupled to the intermediate portion and the lower coupling portion extends in a first direction away from the intermediate portion to the second end of the lower coupling portion, wherein the rear surface faces away from the second end of the lower coupling portion, and wherein applying pressure to the rear surface in a second direction causes the upper coupling portion to move towards the lower coupling portion, wherein the second direction is toward a plane that is perpendicular to the first direction.

US Pat. No. 10,507,294

HANDHELD DYSPNEA TREATMENT DEVICE WITH DRUG AND GAS DELIVERY

Koninklijke Philips N.V.,...

11. A portable handheld pressure support system configured to provide recovery from dyspnea of a subject, without needing to be worn by the subject, the system comprising:generating means for generating a pressurized flow of breathable gas;
means for communicating the pressurized flow of breathable gas to the airway of the subject;
coupling means for coupling to a supply including medicament;
first means for selectively controlling a flow including medicament through the coupling means;
sensing means for generating output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas and one or more flow parameters of the flow including medicament flowing through the coupling means;
means for controlling the generating means based on the output signals from the sensing means, in accordance with a positive pressure support therapy regime;
control means for controlling the first means based on the output signals, from the sensing means, conveying the information related to the one or more gas parameters of the pressurized flow of breathable gas and the one or more flow parameters of the flow including medicament flowing through the medicament inlet port in order to release the obtained flow including medicament into the pressurized flow of breathable gas for inhalation by the subject;
power means for portably powering the generating means, the sensing means, and the first means;
housing means for containing the generating means, the sensing means, the first means, and the power means; and
means for engaging a hand of the subject to be grasped by the subject, the means for engaging being configured to be grasped by the hand of the subject to hold the housing means such that the means for communicating is carried with the housing means for containing into position with respect to the airway of the subject, the means for engaging being connected to and/or formed by the housing means.

US Pat. No. 10,507,286

CONTAINER FOR MIXING AND DISPENSING TWO COMPONENTS

3M Innovative Properties ...

1. A container, comprising:a body having a longitudinal axis, a first end with a first aperture, a second end including a second aperture opposite the first end, and a bypass disposed between the first and the second end;
wherein the bypass has a length L;
a first plug slidably disposed in the body proximate the first end;
a second plug slidably disposed in the body between the first plug and the second end;
wherein the first plug and the second plug define opposite ends of a first compartment disposed in the body between them;
wherein a second compartment is disposed in the body between the second plug and the second end;
wherein the second plug includes:
a top surface facing the first plug;
a bottom surface facing the second end;
a side wall extending between the top surface and the bottom surface, the side wall comprising a circumferential first seal having a first edge proximate the top surface and a circumferential second seal having a second edge proximate the bottom surface; and
a plurality of spaced-apart primary conduits extending through the second plug, each one of the plurality of spaced-apart primary conduits extends from a respective first opening in the side wall to a respective second opening in the bottom surface;
wherein each respective first opening is disposed between the circumferential first seal and the circumferential second seal
wherein at least one of the plurality of spaced-apart primary conduits directs liquid flow out of its respective second opening along a line that is not parallel to the longitudinal axis;
wherein a distance D extends longitudinally from the first edge to the second edge;
wherein a distance E extends longitudinally from the first edge to the separate first openings that are nearest the first edge;
wherein D?L and E

US Pat. No. 10,507,272

WEARABLE VAD CONTROLLER WITH RESERVE BATTERY

WorldHeart, Inc., Miami ...

1. A method of providing a reserve power source for a ventricular assist device, the method comprising:powering the ventricular assist device with a primary power source, the primary power source including at least one from the group consisting of an external battery and AC mains;
monitoring power provided to the ventricular assist device by the primary power source; and
powering the ventricular assist device with a reserve power source disposed within a controller housing when the monitored power is inadequate to run the ventricular assist device, the ventricular assist device being disposed subcutaneously within a patient, the controller housing being disposed externally of the patient and including a first port for connecting to external battery of the primary power source and a second port for connecting to the AC mains of the primary power source, and the ventricular assist device and the controller housing being connected by a percutaneous cable.

US Pat. No. 10,507,271

FULLY IMPLANTABLE DIRECT MYOCARDIUM ASSIST DEVICE

CorInnova Incorporated, ...

1. An implantable cardiac compression device comprising:an inflatable cardiac compression device comprising a resilient inner panel in contact with a heart periphery comprising one or more membranes contoured to provide curvatures generally in the shape of the heart to affect the end-diastolic heart volume, an inflatable outer panel comprising a plurality of inflatable membranes positioned completely around the resilient inner panel to inflate to affect the end-systolic heart volume completely around the heart periphery, and a fluid connection in communication with the inflatable outer panel for inflation and deflation;
an expandable fluid reservoir in communication with the fluid connection and is adapted to be positioned adjacent the pericardium and configured to house a fluid when displaced from the inflatable cardiac compression jacket; and
a fluid driver operably connected to the inflatable cardiac compression jacket and to the expandable fluid reservoir, wherein the fluid driver is configured to fill the cardiac compression jacket with the fluid at least partially removed from the expandable fluid reservoir during systolic ejection by the heart and is further configured to fill the expandable fluid reservoir with fluid at least partially removed from the cardiac compression jacket during diastolic filling of the heart.

US Pat. No. 10,507,234

METHODS AND PHARMACEUTICAL COMPOSITIONS FOR INDUCING IMMUNE TOLERANCE BY MUCOSAL VACCINATION WITH FC-COUPLED ANTIGENS

INSERM (INSTITUT NATIONAL...

1. A method for inducing tolerance to a pancreatic beta cell antigen of interest in a subject in need thereof, comprising mucosally administering to the subject a therapeutically effective amount of a recombinant chimeric construct comprising a FcRn targeting moiety and a preproinsulin peptide comprising the pancreatic beta cell antigen.

US Pat. No. 10,507,202

NAPROXEN-BASED NON-STEROIDAL ANTI-INFLAMMATORY DRUG WITH LOW GASTRIC TOXICITY

Kazan Federal University,...

1. A non-steroidal anti-inflammatory drug based on naproxen formula (I):having anti-inflammatory, analgesic and antipyretic activity, as well as reduced acute toxicity and gastric toxicity.

US Pat. No. 10,507,195

TAXANE PARTICLES AND THEIR USE

Crititech, Inc., Lawrenc...

1. A composition, comprising particles including at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, wherein the particles have a specific surface area (SSA) of at least 18 m2/g, and wherein the taxane particles include both agglomerated taxane particles and non-agglomerated taxane particles.

US Pat. No. 10,507,184

IMPLANTABLE NALTREXONE TABLETS

RUSAN PHARMA LIMITED, Ka...

1. A naltrexone implantable tablet composition comprising naltrexone in an amount of 500 to 2000 mg, wherein, the composition is devoid of magnesium salts and corticosteroids, to provide a controlled amount of the active over a period of 3 months or more;wherein the implantable tablet composition comprises a granulate of 20 to 100 mg of a biodegradable polyester and the naltrexone.

US Pat. No. 10,507,180

SMALL VOLUME ORAL TRANSMUCOSAL DOSAGE FORMS CONTAINING SUFENTANIL FOR TREATMENT OF PAIN

AcelRx Pharmaceuticals, I...

1. A dosage form for oral transmucosal administration to a subject, comprising: an analgesic drug, wherein said dosage form is bioadhesive and has a volume of less than 30 microliters or a mass of less than 30 mg.

US Pat. No. 10,507,158

PATIENT SUPPORT APPARATUS HAVING AN INTEGRATED LIMB COMPRESSION DEVICE

Hill-Rom Services, Inc., ...

1. A patient support apparatus comprisinga frame including a patient support deck,
control circuitry carried by the frame,
a footboard coupled to the frame and having a first interior region,
a compression module located within an interior region of the footboard, the compression module having a housing and a second interior region in the housing, the second interior region being in pneumatic communication with the first interior region through at least one first opening in the housing,
a sleeve port pneumatically coupled to the compression module, the sleeve port being configured for attachment to at least one tube extending from a compression sleeve that is worn on a limb of a patient, and
an electrical cable providing wired communication between the compression module and the control circuitry, the electrical cable extending through a second opening formed in the footboard, wherein during operation of the compression module to inflate the compression sleeve, air moves from ambient surroundings into the first interior region of the footboard through the second opening and air moves into the second interior region in the housing of the compression module through the at least one first opening, wherein the compression module includes a filter and a pump and air entering the second interior region through the at least one first opening passes through the filter before reaching the pump.

US Pat. No. 10,507,150

INTENSIVE USE FURNITURE

Norix Group, Inc., West ...

1. An intensive use bed comprising a molded, non-penetrable outer shell having a generally horizontal top, a bottom, a pair of generally vertical end walls, a generally vertical first side wall, a generally vertical second side wall and a plurality of mounting flanges, each of the generally vertical end walls on the top, the first generally vertical side wall on the top, the first side wall attached to and between the pair of end walls whereby the end walls are in spaced relation and substantially parallel to each other, the second generally vertical side wall on the top, the second side wall attached to and between the pair of end walls, the bottom on the pair of generally vertical end walls, the bottom attached to the first and second side walls whereby the top and bottom are in spaced relation and substantially parallel to each other, each of the plurality of mounting flanges comprising a bolt hole extending through the bottom, one of the plurality of mounting flanges disposed in a first one of the pair of end walls adjacent the bottom, another one of the plurality of mounting flanges disposed in the first side wall adjacent the bottom, a first end support ridge in the first one of the pair of end walls, a first side support ridge disposed in the first side wall, a recessed pocket in the top, a recessed pocket in the bottom.

US Pat. No. 10,507,135

OPHTHALMIC TREATMENT APPARATUS AND TREATMENT BEAM RADIATING METHOD FOR SAID APPARATUS

LUTRONIC VISION INC., Bu...

1. An ophthalmic treatment apparatus, comprising:a beam generation unit which generates a beam for treatment; and
a beam delivery unit which guides the beam for treatment generated by the beam generation unit to a retina region of an eyeball; and
an imaging unit which generates an image of the retina region of the eyeball in a direction perpendicular to at least one plane of at least one focal spot of the beam for treatment that is guided by the beam delivery unit,
wherein the ophthalmic treatment apparatus controls the beam delivery unit so that a location of the at least one plane of the at least one focal spot to which the beam for treatment is radiated is controlled based on curvature of the retina region of the eyeball photographed by the image unit,
wherein the at least one plane includes a plane of a first focal spot and a plane of a second focal spot which is separated by a distance from the plane of the first focal spot, and the beam delivery unit radiates the beam for treatment to the retina region of the eyeball in a pattern comprising a plurality of focal spots, and
wherein a controller divides the pattern into a reference pattern located on the plane of the first focal spot and a control pattern located on the plane of the second focal spot and controls the beam delivery unit to radiate the first pattern onto the first focal spot and, after terminating radiation of the first pattern, to radiate the second pattern onto the second focal spot,
wherein the plane of the first focal spot forms a tangential plane in an arc of the retina region of the eyeball through which an optical axial line of the beam for treatment penetrates,
wherein the plane of the second focal spot is parallel to the plane of the first focal spot along the optical axial line and connects both ends of an arc formed with a contact point of the retina region interposed between the two sides,
wherein the separation distance between the plane of the first focal spot and the plane of the second focal spot corresponds to the curvature of the retina region of the eyeball,
wherein the ophthalmic treatment apparatus analyzes the image of the retina region of the eyeball transmitted by the image unit and measures the separation distance between the plane of the first focal spot and the plane of the second focal spot, and
wherein the ophthalmic treatment apparatus controls an operation of the beam delivery unit so that the beam for treatment is radiated to the plane of the first focal spot and the plane of the second focal spot based on the separation distance between the plane of the first focal spot and the plane of the second focal spot.

US Pat. No. 10,507,133

INJECTABLE SECUREMENT DEVICE AND RELATED DELIVERY SYSTEM AND METHOD OF USE

THE REGENTS OF THE UNIVER...

1. A system for grasping an intraocular object comprising:an injectable securement device comprising a suture forming a securement through and around a bolster, wherein applying tension to the suture cinches a closed loop of the securement against the bolster to grasp an intraocular object extending through the loop and secure the intraocular object against the bolster, wherein the bolster is comprised of a material that is resiliently deformable such that the suture deforms the bolster when the suture is pulled tight around the bolster to prevent unraveling of the loop and slipping of the securement, and further wherein the suture is threaded through the bolster along two different axes of the bolster; and
an elongate element having a lumen extending therethrough, the elongate element comprising an actuator mechanism, and the elongate member being configured to pierce tissue with a distal end, wherein the suture is threaded through the elongate element, and wherein the injectable securement device is configured to be deployed from the distal end by the actuator mechanism.

US Pat. No. 10,507,127

EXPANDABLE DEVICE

EPITOMEE MEDICAL LTD., C...

1. A folded device encased in a gastric degradable swallowable encasing, the folded device comprising at least one compartment defined by a space enclosed by walls formed by an external enterically biodegradable film having a thickness of between about 3 and about 60 microns, the external enterically biodegradable film enclosing a gel-film comprising particles of at least one gel-forming compound, said gel-film having a thickness of between about 50 and about 300 microns, or a thickness of about 400, about 500, about 600, about 700, or about 800 microns, wherein upon delivery to a stomach of a subject,the folded device is transformable into an unfolded expanded form as the encasing degrades and the particles comprised in said gel-film undergo swelling with a swelling ratio of about 10 to about 100 times-fold and wherein the biodegradable film disintegrates after the device leaves the stomach.

US Pat. No. 10,507,125

STENT

Medfirst AG, Balzers (LI...

1. A stent for transluminal implantation into hollow organs, the stent comprising:a substantially tubular body extending in a longitudinal direction, wherein the substantially tubular body is configured to be converted from a compressed state having a first cross-sectional diameter into an expanded state having an enlarged second cross-sectional diameter,
wherein the stent comprises a plurality of groups of cells in the expanded state,
wherein each group of cells comprises an equal number of cells,
wherein each group of cells comprises three or more diamond-shaped cells that are defined by bordering elements formed by the tubular body and defined by connection sections at locations where the bordering elements intersect,
wherein adjacent diamond-shaped cells of each group of cells are connected by one of the connection sections,
wherein each group of cells is arranged so that the connection sections connecting adjacent diamond-shaped cells in each group of cells are oriented in a straight line that is parallel to the longitudinal direction,
wherein diamond-shaped cells of a first group of the plurality of groups of cells are more elongated in the longitudinal direction than diamond-shaped cells of a second group of the plurality of groups of cells in order to form a chamfered front face end of the stent.

US Pat. No. 10,507,119

SPINAL INTERBODY DEVICE, SYSTEM AND METHOD

AESCULAP IMPLANT SYSTEMS,...

1. A spinal interbody device, comprising:an interbody device configured to be placed between adjacent vertebrae of a spinal column, the interbody device including,
an anterior surface,
a posterior surface substantially opposed to the anterior surface,
a lateral surface extending from the anterior surface to the posterior surface,
a medial surface opposed to the lateral surface and extending from the anterior surface to the posterior surface,
a superior surface connected to each of the anterior surface, posterior surface, lateral surface, and medial surface,
an inferior surface opposed to the upper surface and connected to each of the anterior surface, posterior surface, lateral surface, and medial surface,
an opening extending from the superior surface through the inferior surface, and at least one projection extending from at least one of the superior surface and inferior surface of the interbody device, the at least one projection including a self cutting structure, and the at least one projection configured to prevent movement of the interbody device relative to the adjacent vertebrae when implanted, wherein the self cutting structure includes a first face and a second face and a blade defined by the first face and the second face, a back surface formed opposite to the blade, the blade facing in a direction of implantation of the interbody device, and
a ledge surface formed in front of the first face and the second face and opposite to the back surface,
wherein the first face and the second face ramp upwardly from the ledge surface to form the blade.

US Pat. No. 10,507,118

3D PRINTED OSTEOGENESIS SCAFFOLD

MCA Group, LLC, Menlo Pa...

1. An osteogenesis scaffold configured for spinal fusion, comprising:a superior support surface;
an inferior support surface;
a plurality of arcuate struts separating the superior and inferior support surfaces, the plurality of arcuate struts configured to permit a predetermined amount of compression of the scaffold in a superior to inferior direction by deformation of at least some of the arcuate struts and the plurality of arcuate struts comprising a material having a strut material modulus;
the scaffold having a functional modulus which is different than the strut material modulus and is the result of the strut modulus and the architecture of the implant.

US Pat. No. 10,507,114

UNIVERSAL PROSTHETIC HEAD FOR HIP PROSTHESIS

1. A prosthetic head for fixing to a cotyle of a hip prosthesis, the prosthetic head comprising:a body having a concave shape, said body having an external surface and an internal surface and a lower edge, the lower edge defining a circumference of said body;
a plurality of through holes formed in said body;
a plurality of screws extending respectively through at least some of said plurality of through holes, said plurality of screws adapted to be screwed into the cotyle;
a projection extending from the internal surface of said body so as to define an annular;
a truncated-conical portion formed in the internal surface of said body and extending from the lower edge of said body, said truncated-conical portion adapted to couple with a truncated-conical portion of an insert received in said body;
an insert having an external surface and an internal surface, said insert having a truncated-conical part coupled with the truncated-conical portion of said body, said insert having an annular step extending from the internal surface of said insert and having a projection of a Morse cone shape extending from the annular step;
a ball having a cavity of a Morse cone shape, the cavity housing the projection of said insert; and
a distal cup adapted to be fixed to a stem that is to be attached to a femur, said distal cup having a concave cap shape, said distal cup receiving said ball therein.

US Pat. No. 10,507,111

MAGNETIC PROSTHETIC

1. An artificial joint prosthesis, comprising:a bone-facing surface configured to face a bone-prosthesis interface in vivo;
a first component comprising a contact surface, the first component fabricated, via at least an additive manufacturing method, from at least one polymer including a plurality of magnetic particles embedded in a first polymer matrix; and
a second component fabricated, via at least an additive manufacturing method, from at least one polymer including a plurality of magnetic particles embedded in a second polymer matrix;
wherein the plurality of magnetic particles embedded in at least one of the first polymer matrix and the second polymer matrix is distributed within the surrounding polymer as a variable magnetic fraction comprising a variable composition between 70.0% and 90.0% magnetic material and is configured to create a magnetic field about the artificial joint, directed to facilitate articulation of the artificial joint in vivo.

US Pat. No. 10,507,081

METHODS FOR TAKING AN IMPRESSION OR SCANNING WITHOUT REQUIRING REMOVAL OF A TEMPORARY HEALING ABUTMENT

ESTHETIC IMPLANT SOLUTION...

1. A method of taking an impression or scan of a patient's oral cavity, the method comprising:providing an anatomical healing abutment/cap received within a subgingival void of a given tooth position, the anatomical healing abutment/cap being threadably coupled into an implant disposed adjacent the anatomical healing abutment/cap; and
providing a scanning body or impression post that is initially separate from the anatomical healing abutment/cap, and inserting the scanning body or impression post into an open end of the anatomical healing abutment/cap with the anatomical healing abutment/cap positioned in the subgingival void, such that insertion of the scanning body or impression post occurs without requiring removal of the anatomical healing abutment/cap;
wherein the scanning body or the impression post is selectively removable from the open end of the anatomical healing abutment/cap, and a screw is not required to selectively secure the scanning body or the impression post to the open end of the anatomical healing abutment/cap, such that the scanning body or impression post is slidably received into the open end of the anatomical healing abutment/cap, and the anatomical healing abutment/cap is threadably coupled into the implant;
wherein the anatomical healing abutment/cap and the scanning body or impression post are keyed to one another;
wherein the anatomical healing abutment/cap comprises one or more vertical grooves formed into an interior surface of the anatomical healing abutment/cap;
wherein an exterior surface of the scanning body or impression post inserted into the anatomical healing abutment/cap includes one or more vertical protrusions which mate with the one or more vertical grooves of the anatomical healing abutment/cap; and wherein:
the one or more vertical grooves comprise a plurality of vertical grooves which are of different lengths and/or widths relative to one another; and
the one or more vertical protrusions comprise a plurality of vertical protrusions which are of different lengths and/or widths relative to one another.

US Pat. No. 10,507,069

OPERATING DEVICE FOR A ROBOT-ASSISTED SURGICAL SYSTEM

avateramedical GmbH, Jen...

1. An operating device for a robot-assisted surgery system, comprising;a manually actuatable user operated element comprising two straps for receiving one finger of a user each; and
an interface for attaching the operating device to a holding unit;
wherein the user operated element, when the operating device is attached to the holding unit, is rotatable relative to the interface about a first axis of rotation, a second axis of rotation and a third axis of rotation, the three axes of rotation each being orthogonal to each other;
wherein the three axes of rotation intersect in a common point of intersection; and
wherein the user operated element includes a disk-like body.

US Pat. No. 10,507,068

ROBOTIC SURGICAL SYSTEM TORQUE TRANSDUCTION SENSING

Covidien LP, Mansfield, ...

1. An instrument drive unit of a robotic surgical system, the instrument drive unit comprising:a fixed plate;
a first motor having a first drive shaft;
a first reaction torque transducer disposed about the first drive shaft to secure the first motor to the fixed plate and being configured to detect torque delivered by the first motor;
a first controller for controlling the first motor, the first controller in communication with the first sensor and the first reaction torque transducer, the first controller configured to compare the detected current drawn by the first motor to the detected torque delivered by the first motor to verify the detected torque is within an acceptable range of torque values for the detected current drawn by the first motor;
a second motor having a second drive shaft;
a second reaction torque transducer disposed about the second drive shaft to secure the second motor to the fixed plate and being configured to detect torque delivered by the second motor; and
a second sensor configured to detect current drawn by the second motor, wherein the first controller is configured to control the second motor, the first controller in communication with the second sensor and the second reaction torque transducer, the first controller configured to compare the detected current drawn by the second motor to the detected torque delivered by the second motor to verify the detected torque is within an acceptable range of torque values for the detected current drawn by the second motor.

US Pat. No. 10,507,065

SYSTEM AND METHOD FOR ENHANCED DATA ANALYSIS WITH VIDEO ENABLED SOFTWARE TOOLS FOR MEDICAL ENVIRONMENTS

1. A system for medical software tools, comprising:an image stream interface module configured to receive an image stream from a surgical camera wherein said image stream interface module includes a CPU and a GPU for processing said image stream;
a user interface overlay module configured to provide a user interface overlay adapted for presentation over the image stream by use of a video router providing a video stream to overlay an original video image;
an optical sensor located corresponding with said surgical camera for registering momentary changes in spectral characteristics reflected from a tissue surface under inspection wherein said optical sensor provides a signal indicative of light energy detected;
a medical software tools module configured to provide a medical software tool through the user interface, the medical software tool being configured to perform an operation with respect to the image stream and provide an output adapted to be presented over the image stream, responsive to said light energy detected by said optical sensor;
a medical image processing system for processing patient medical data and corresponding said patient medical data with said momentary changes in spectral characteristics for generating optical signature data indicative of various patient conditions, wherein the medical software tool measures: a. changes in color intensity and b. rates at which said color intensities change in response to: heartbeat pushed blood, breathing pushed oxygen or light intensity or modulation from a light source; and
wherein a contrast fluorescent dye is introduced associated with said tissue under inspection in the assessment of the perfusion of tissues and organs.

US Pat. No. 10,507,054

SYSTEM AND METHOD FOR DETECTING AND SUPRESSING ARC FORMATION DURING AN ELECTROSURGICAL PROCEDURE

Covidien LP, Mansfield, ...

1. An electrosurgical system comprising:an electrosurgical generator configured to supply a plurality of pulses to an electrosurgical instrument for tissue treatment; and
a current limiting circuit operably coupled to the electrosurgical generator and configured to measure an instantaneous attribute of each pulse of the plurality of pulses for independent comparison with a predetermined threshold within a duration of time of each pulse of the plurality of pulses,
wherein a duty cycle of the plurality of pulses is reduced and prior to completion of the duration of time each pulse is terminated based on the comparison between the measured instantaneous attribute and the predetermined threshold.

US Pat. No. 10,507,049

FLEXIBLE PLATE FIXATION OF BONE FRACTURES

Zimmer, Inc., Warsaw, IN...

1. A device, comprising:a bone fracture fixation plate having an upper surface and a bone-facing surface, the bone plate comprising one or more slots extending through the bone plate from the upper surface to the bone-facing surface, the one or more slots at least partially circumscribing a periphery of one or more non-expandable threaded receiving holes to enable displacement of the one or more threaded receiving holes within the bone plate along a longitudinal axis of the bone plate, wherein the one or more threaded receiving holes are disposed within one or more insert members, respectively, and wherein the one or more insert members include a recessed channel disposed along a side surface of the insert member.

US Pat. No. 10,507,048

FEMORAL NECK FRACTURE IMPLANT

DePuy Synthes Products, I...

1. A device for aiming a bone fixation system, comprising:an insertion instrument including a shaft extending from a proximal end to a distal end and an arm coupled to the proximal end of the shaft, the distal end of the shaft including an engagement portion configured to removably engage a proximal end of a bone fixation device, the arm including an elongated channel extending therethrough along a channel longitudinal axis, the shaft including an elongated slot extending along a sidewall thereof such that the elongated slot is open to the elongated channel; and
an elongated member removably insertable through the elongated channel, the elongated member including a first shaft portion and a second shaft portion, the second shaft portion including a guide channel extending therethrough along a guide axis, wherein, when the elongated member is inserted into the elongated channel, the first shaft portion extends along the channel longitudinal axis and the second shaft portion extends through the elongated slot so that the second shaft portion is angled to extend nonparallel to the channel longitudinal axis and the first shaft portion to guide insertion of an anti-rotation screw through the guide channel into a first opening of the bone fixation device.

US Pat. No. 10,507,042

NON-FUSION SCOLIOSIS EXPANDABLE SPINAL ROD

DEPUY SYNTHES PRODUCTS, I...

1. A drive mechanism for a growing rod, comprising:an inner housing comprising a magnet assembly including a magnet having a first pole and a second pole and a gear reduction mechanism coupled to the magnet such that the magnet assembly and the gear reduction mechanism rotate freely within the inner housing, the gear reduction mechanism reducing an output rotation of the magnet; a bearing slidingly coupled to a circumferential outer surface of the inner housing;
a driver rotationally coupled to the gear reduction mechanism, the driver coupled to the gear reduction mechanism such that a longitudinal spacing therebetween is fixed;
an outer housing coupled to the inner housing by engagement of the driver with an inner surface of the outer housing,
wherein the bearing engages the outer housing and the inner housing to prevent the inner housing from spinning freely within the outer housing,
wherein rotation of the magnet assembly causes the gear reduction mechanism to rotate the driver to cause the inner housing to move along a longitudinal axis substantially without rotation relative to the outer housing.

US Pat. No. 10,507,029

PATIENT-SPECIFIC ACETABULAR GUIDES AND ASSOCIATED INSTRUMENTS

Biomet Manufacturing, LLC...

2. An acetabular guide comprising:a patient-specific engagement surface designed to be complementary and mateable with a corresponding surface of the patient's pelvic anatomy as determined during a pre-operative plan of the patient by a three-dimensional reconstruction of the anatomy of the patient using two-dimensional medical images, the patient-specific engagement surface having a first portion mateable with a portion of an acetabulum of the patient;
a guiding element extending from the acetabular guide opposite to the first portion of engagement surface, the guiding element defining a bore designed to be oriented along an alignment axis for an acetabular implant when the acetabular guide is engaged to the acetabulum; and
first and second marker elements extending from a portion of the acetabular guide outside the acetabulum of the patient, the marker elements defining corresponding first and second bores for guiding first and second marker pins into a bone portion of the patient.

US Pat. No. 10,507,023

SELF-CENTERING SPIRAL FILTER

Cook Medical Technologies...

1. A filter for implantation in a body lumen, the filter comprising:a first loop having a first radius;
a second loop having a second radius, at least one of the first loop and the second loop being arcuately disposed about a longitudinal axis of the filter; and
a helical portion helically extending from the first loop to the second loop and comprising a plurality of turns, each turn having a radius of curvature increasing in the longitudinal direction from the first loop to the second loop;
wherein the filter is movable between a collapsed configuration and an expanded configuration, and
wherein at least one of the first loop, the second loop, and at least one turn of the helical portion are aligned at an angle of between 10 degrees and 50 degrees relative to the longitudinal axis when in the expanded configuration.

US Pat. No. 10,507,020

IMPLANTABLE FASTENER FOR ATTACHMENT OF A MEDICAL DEVICE TO TISSUE

Tepha, Inc., Lexington, ...

1. An implantable fastener for attachment of a medical device or implantable component to tissue comprising a plurality of tissue retainers emanating from a supportive backing,wherein the tissue retainers comprise two tips, and are configured to swivel from a plane of the supportive backing to engage tissue,
wherein a tip of the tissue retainer projects from each side of the plane of the supportive backing, and
wherein the fastener is attached to a medical device.

US Pat. No. 10,507,017

WOUND RETRACTOR

Applied Medical Resources...

1. An adjustable wound retractor adapted to dilate a surgical wound incision to a desired diameter, comprising:a first ring having a diameter greater than the desired diameter of the wound incision and being adapted for disposition interiorly of the wound incision;
a second ring having a diameter greater than the desired diameter of the wound incision and being adapted for disposition exteriorly of the wound incision;
a flexible sleeve disposed in a generally cylindrical form between the first ring and the second ring, a distal end of the sleeve attached to the first ring and a proximal end of the sleeve attached to the second ring, wherein a distance between the first ring and the second ring is adjustable;
a ring-shaped base comprising a smooth, generally cylindrical surface disposed around the base to form a curved channel, wherein the smooth generally cylindrical surface extends proximally to a first rounded end surface and distally to a second rounded end surface, and wherein the channel is adapted to receive the second ring and thereby attach the base to the second ring and;
at least one toggle, wherein the toggle extends proximally from the second rounded end surface.

US Pat. No. 10,507,007

OPHTHALMIC ULTRASOUND BIO-MICROSCOPE (UBM) APPARATUS

Dov Helbetz, Herzliya (I...

1. Ophthalmic Ultrasound Bio-Microscope (UBM) apparatus for examining an eye of a human subject in a supine position, the ophthalmic UBM apparatus including a vertical UBM examination centerline, the ophthalmic UBM apparatus comprising:(a) an illuminated overhead fixation target deployed along the vertical UBM examination centerline for direct fixation by the examined eye for fixating its visual axis therealong;
(b) a UBM scanner including a UBM probe having a UBM probe axis directed towards the examined eye, said UBM probe having a known spatial position with respect to said overhead fixation target,
said UBM probe having a UBM transducer and a motorized probe arrangement for reciprocation of said UBM transducer along a predetermined scan path for acquiring a vertical UBM scan of the examined eye at a predetermined UBM examination height relative to the examined eye, said scan path being lateral to the UBM examination centerline to preclude said UBM transducer intercepting said direct fixation of the examined eye on said illuminated overhead fixation target;
(c) a motorized UBM scanner rotation arrangement for selectively rotating said UBM scanner around the UBM examination centerline to an annular set of predetermined clock time probe positions wherein said annular set of predetermined clock time positions includes at least one diametric pair of clock time probe positions;
(d) a motorized UBM examination height adjustment arrangement for selectively adjusting said UBM examination height of said UBM scanner relative to the examined eye to at least two predetermined UBM examination heights; and
(e) an image processing module for processing said vertical UBM scans for determining ophthalmic information regarding the examined eye, said ophthalmic information including computerized vertical cross sections of at least an anterior chamber of an anterior segment of the examined eye wherein each computerized vertical cross section is constructed from UBM scans acquired at at least two diametric pair of clock time probe positions.

US Pat. No. 10,507,004

PHANTOM DEVICE, DARK FIELD IMAGING SYSTEM AND METHOD FOR ACQUIRING A DARK FIELD IMAGE

KONINKLIJKE PHILIPS N.V.,...

1. A phantom device for a dark field imaging system, the phantom device comprising:a main body,
reference parts formed of an attenuation part and a de-coherence part being stacked on the attenuation part, such that the attenuation part and the de-coherence part of the respective reference part are arranged consecutively along a predefined direction of the main body;
wherein each de-coherence part is configured to cause de-coherence disturbance to an X-ray beam, if said X-ray beam passes the respective de-coherence part along the predefined direction;
wherein each attenuation part is configured to cause attenuation disturbance to an X-ray beam, if said X-ray beam passes the respective attenuation part along the predefined direction;
wherein the main body comprises a first group of at least two reference parts;
wherein each of the de-coherence parts of the first group are configured to cause the same first degree of de-coherence disturbance; and
wherein the attenuation parts of the first group are configured to cause mutually different degrees of attenuation disturbance.

US Pat. No. 10,506,998

AGENT-BASED IMAGING

KONINKLIJKE PHILIPS N.V.,...

1. A method, comprising:receiving, by an imaging system, scan parameters for an agent-based imaging procedure from a selected scan protocol for the agent-based imaging procedure,
wherein the imaging system includes a computed tomography or a positron emission tomography scanner, the scan protocol includes injector delivery parameters for the agent-based imaging procedure, and the injector delivery parameters are selected from a group consisting of: a delivery rate, a delivery volume, or a delivery pressure;
configuring the imaging system for the agent-based imaging procedure with the scan parameters;
determining, during a pre-scan validation check of an injector, that the injector is configured to deliver a contrast agent using the injector delivery parameters during the agent-based imaging procedure;
scanning, in response to determining that the injector is configured to deliver the contrast agent using the injector delivery parameters during the agent-based imaging procedure, a subject with the imaging system during the agent-based imaging procedure, which produces imaging data of the subject for the agent-based imaging procedure;
receiving, by the imaging system, agent delivery information of an agent delivered to the subject with the injector during the agent-based imaging procedure and sent by the injector to the imaging system;
correlating, by the imaging system, the agent delivery information with the imaging data as a function of time;
constructing a graph of the agent delivery information with the image data as a function of the time based on a result of the correlating;
displaying the graph;
receiving an input indicating a time point of interest on the graph; and
displaying the agent delivery information for the time point based on the result of the correlating.

US Pat. No. 10,506,996

MEDICAL IMAGING DEVICE WITH SEPARATE BUTTON FOR SELECTING CANDIDATE SEGMENTATION

KONINKLIJKE PHILIPS N.V.,...

1. A medical imaging device comprising:an image acquisition device configured to acquire an image of a region of interest in a patient body;
an image segmentation device configured to automatically identify anatomic or device structures within an acquired image using image segmentation techniques, wherein the image segmentation device is further configured to provide a plurality of candidate images representing differently identified anatomic or device structures;
a visualization device configured to visualize the plurality of candidate images on a display; and
a separate user interface consisting of a separate selection button,
wherein the imaging device is configured for manual selection of one candidate image out of the plurality of candidate images only by activating the selection button,
wherein the separate user interface consisting of the selection button is spatially separate from the display and is provided in addition to and separate from other input devices configured for inputting data to a computing device and is also connected to the computing device, and
wherein the separate user interface consisting of the selection button is located at a patient table configured to support the patient body for being easily handled during a medical intervention by an intervening physician.

US Pat. No. 10,506,995

MOBILE X-RAY IMAGING DEVICE

Hitachi, Ltd., Tokyo (JP...

1. A mobile X-ray imaging device comprising,an X-ray tube unit,
a main body configured to accommodate a drive unit of the X-ray tube unit,
wheels mounted on the main body, and
an arm unit configured to connect the X-ray tube unit with the main body,
wherein the arm unit comprises a plurality of arms being foldable, and the main body has a storage concave for storing the arm unit being folded,
wherein the plurality of arms include a first arm and a second arm which is foldable with respect to the first arm, the first arm and the second arm being stored in the storage concave in a folded position and extending outside the storage concave in an unfolded position, and
wherein the first arm has one end which is slidably coupled to the storage concave and the second arm has one end which is attached to the X-ray tube unit.

US Pat. No. 10,506,990

DEVICES AND METHODS FOR FALL DETECTION BASED ON PHASE SEGMENTATION

QUALCOMM Incorporated, S...

1. A method of identifying a fall event using a wearable electronic monitoring device, wherein the wearable electronic monitoring device includes one or more processors and one or more motion sensors coupled to the one or more processors, the method comprising:accessing, from the one or more motion sensors of the wearable electronic monitoring device, acceleration data indicative of motion of a user of the wearable electronic monitoring device;
segmenting, by the one or more processors, the acceleration data into at least three phases using a segmentation algorithm to identify a potential fall event, comprising:
determining a cumulative sum for the acceleration data; and
identifying the potential fall event in the acceleration data where the cumulative sum is greater than a cumulative sum threshold value, wherein the acceleration data is segmented into the at least three phases using the cumulative sum for the acceleration data;
extracting, by the one or more processors, one or more statistical features from the segmented acceleration data;
determining, by the one or more processors, whether the potential fall event is a fall event based at least in part on the one or more extracted statistical features,
generating an alarm signal from the wearable electronic device based on the one or more processors determining the potential event to be a fall event.

US Pat. No. 10,506,985

METHODS AND SYSTEMS FOR DIAGNOSING OR MONITORING PROGRESS OF A PATHOLOGY USING LASER INDUCED BREAKDOWN SPECTROSCOPY AND BIOLOGICAL FLUIDS

The University of Massach...

1. A method for diagnosing or monitoring progress of a pathology using laser induced breakdown spectroscopy (LIBS) and biological fluids, the method comprising:depositing a sample of a predetermined biological fluid on a predetermined substrate;
focusing light from a laser source on the sample deposited on the predetermined substrate; energy and pulse length of the laser source being configured to cause ablation of the sample and the predetermined substrate and formation of a plasma;
collecting optical emission from the plasma using an optical detection system;
providing collected optical emission to a spectroscopic acquisition component; the spectroscopic acquisition component providing information on spectral data;
providing the spectral data from the collected optical emission to a processing component; the processing component comprising one or more processors;
using a machine learning algorithm and the one or more processors to diagnose the pathology or monitor progress of the pathology; wherein the machine learning algorithm is trained on a training set comprising spectral data for LIBS collected optical emission from samples of the predetermined biological fluid on the predetermined substrate which have known pathology or known progress of the pathology;
wherein the predetermined substrate has ionization energy lower than ionization energies of C or H and is also configured to provide higher signal-to-noise ratio than other candidate substrates with ionization energy lower than ionization energies of C or H and also configured to provide higher classification accuracy, obtained using the machine learning algorithm, of greater than a predetermined value.

US Pat. No. 10,506,976

SYSTEM FOR MONITORING RESPIRATION

Spire, Inc., San Francis...

1. A system for monitoring respiration comprising:a housing configured to be removably attached to clothing worn by a user, the housing being at least partially flexible;
a respiration sensor enclosed within the housing and coupled to the housing, the respiration sensor comprising a capacitive sensor with first and second conductive plates positioned parallel to one another and separated by a non-rigid material, the respiration sensor configured to generate a respiration signal based on a change in capacitance responsive to movements of the user's body produced by the user's breathing being applied to the housing;
an activity sensor enclosed within the housing, the activity sensor configured to generate an activity signal associated with activity performed by the user; and
electronics enclosed within the housing, the electronics comprising a processor coupled to the respiration sensor and the activity sensor, the processor configured to:
transform the respiration signal and the activity signal into a dataset characterizing at least one respiration characteristic of the user and an activity contemporaneously performed by the user;
associate the activity determined from the activity signal with a portion of the dataset;
extract the at least one respiration characteristic from a portion of the dataset associated with the activity; and
generate a user notification indicative of respiration of the user based on a result of analysis of the at least one respiration characteristic and a comparative respiration characteristic extracted from another occurrence of the activity.

US Pat. No. 10,506,969

ACOUSTIC UPPER AIRWAY ASSESSMENT SYSTEM AND METHOD, AND SLEEP APNEA ASSESSMENT SYSTEM AND METHOD RELYING THEREON

UNIVERSITY HEALTH NETWORK...

1. A non-invasive method for assessing upper airway anatomy in a subject while breathing to output an indication on sleep apnea severity, the method comprising:receiving as input at a hardware processor a digital signal representative of respiratory sounds generated by the subject while breathing;
isolating digital respiratory sound segments of interest from said digital signal;
computationally extracting a designated spectral feature from each of said segments to characterize said respiratory sound within each of said segments;
automatically evaluating each said extracted spectral feature against a preset upper airway anatomy dimension metric defined by a pre-established scale automatically correlating said extracted spectral feature with a given upper airway anatomy measure to characterize said given upper airway anatomy measure in the subject while breathing; and
outputting a sleep apnea severity indication based on said characterized upper airway anatomy measure.

US Pat. No. 10,506,961

DIAGNOSTIC TRANSDUCER AND METHOD

Eden Medical, Inc., Howa...

1. A diagnostic device for assessing ulceration risk in a tissue of a patient, the diagnostic device comprising:a hand-held housing, wherein the hand-held housing includes a user interface;
an extension neck operatively coupled to the hand-held housing at a first end of the extension neck, wherein the extension neck has at least a first range of motion relative to the hand-held housing;
a scan head operatively coupled to the extension neck at a second end of the extension neck, wherein the scan head has at least a second range of motion relative to the extension neck, and wherein the hand-held housing, the extension neck, and the scan head are arranged such that pressure is applied to the tissue of the patient from the scan head by a person holding the hand-held housing, and wherein the scan head includes:
a light-emitting system configured to emit light at a selected wavelength of a predetermined set of wavelengths at a first time and to direct the emitted light into the tissue; and
a photodetector configured to receive light reflected from the tissue and generate an electrical signal based on the received reflected light;
a controller operatively coupled to the user interface and configured to control the light-emitting system and the photodetector; and
a processor operatively coupled to the photodetector and the controller and configured to calculate regional-perfusion-index (RPI) data based at least in part on the electrical signal generated by the photodetector.

US Pat. No. 10,506,952

MOTION MONITOR

BreatheVision Ltd., Hof ...

1. A system for monitoring the respiratory activity of a subject, comprising:a) two or more signal generating elements, wherein each of said signal generating elements being a light emitting element and/or an inertial sensor which generates a signal receivable by a receiver, wherein each of said signal generating elements is applied to the body of a subject, for generating signals that are indicative of movement of the chest and abdomen of said subject throughout a predetermined time period;
b) receiver for receiving said generated signals during breathing motions of said subject; and
c) one or more computing devices in data communication with said receiver, for analyzing said breathing motions,
wherein said one or more computing devices is operable to:
i. generate, by said two or more signal generating elements, signals that are indicative of movements of the chest and abdomen of said subject, throughout said predetermined time period;
ii. calculate the current amplitudes and relative phases of said signal generating elements throughout said predetermined time period; and
iii. calculate, throughout said predetermined time period, the breathing volume from the said amplitudes and said relative phases.

US Pat. No. 10,506,948

LOCALIZATION FOR ELECTROCARDIOGRAPHIC MAPPING

CARDIOINSIGHT TECHNOLOGIE...

1. A system to localize an object in a patient's body, the system comprising:at least one electrode fixed to the object in the patient's body;
a pulse generator configured to generate a localization signal comprising a subthreshold electrical signal and provide the localization signal to the at least one electrode, the subthreshold electrical signal having energy insufficient to stimulate electrical conduction in tissue of the patient's body;
a sensor array configured to detect an electrical field produced in response to the localization signal and provide respective sensor signals; and
a processor configured to:
retrieve geometry data stored in memory, the geometry data representing a geometric relationship between patient anatomy and the sensor array;
reconstruct electrical signals based on the respective sensor signals and the geometry data; and
determine an absolute location where the localization signal was applied based on comparing amplitude and frequency characteristics of each of the reconstructed electrical signals with respect to the localization signal.

US Pat. No. 10,506,945

PATIENT SPECIFIC SCAN PARAMETERS FOR MRI SCANNING

UNIVERSITY OF UTAH RESEAR...

1. A device for performing an MRI scan using patient specific scan parameters, the device comprising:a processor, configured to:
receive a series of MRI scout scan images of a patient infected with a contrast agent;
select an initial inversion time (TIinitial) based on the MRI scout scan images;
determine a time interval between adjacent inversion pulses (TR) based on an ECG from the patient;
calculate a relaxation time (T1) based on TIinitial and TR;
calculate an optimized inversion time (TIoptimized) based on the T1; and
generate an output to the device to perform an MRI scan of the patient based on TIoptimized.

US Pat. No. 10,506,944

APPARATUS FOR ELECTRODERMAL ACTIVITY MEASUREMENT WITH CURRENT COMPENSATION

Empatica Srl, Milan (IT)...

1. An apparatus, comprising:a first electrode configured to be in contact with a first portion of a stratum corneum of skin;
a second electrode configured to be in contact with a second portion of the stratum corneum and in electronic communication with the first electrode through the stratum corneum;
a digital-to-analog converter (DAC) configured to generate a compensation voltage; and
a processor electrically coupled to the first electrode, the second electrode, and the DAC, the processor configured to execute computer-executable instructions to:
(a) bias the first electrode at a first voltage V+ and the second electrode at a second voltage V?;
(b) measure a first current flowing between the first electrode and the second electrode, the first current corresponding to a conductance of the stratum corneum;
(c) subtract a compensation current from the first current to obtain a second current;
(d) amplify the second current and transform the second current to an output voltage;
(e) calculate the conductance of the stratum corneum based on the output voltage, the conductance of the stratum corneum being indicative of an extent of electrodermal activity;
(f) determine whether the output voltage is greater than a threshold value; and
(g) in response to determining that the output voltage is greater than the threshold value, adjust the compensation voltage generated by the DAC to adjust the compensation current subtracted from the first current to prevent saturation of the output voltage.

US Pat. No. 10,506,937

PATIENT ELECTRODE CONNECTORS FOR ELECTROCARDIOGRAPH MONITORING SYSTEM

ADVANTAGE MEDICAL ELECTRO...

1. An electrode connector comprising:a connector body, said connector body having a jaw member, said jaw member pivotally connected to said connector body;
said connector body and jaw member configurable between an open configuration and a closed configuration;
said connector body and said jaw member biased with a biasing member to the closed configuration;
said jaw member defining a beveled bottom edge and a lip, said beveled bottom edge functioning, upon engagement with a head of an electrode stud, to urge said jaw member toward said open configuration, said lip positioned to engage said electrode stud at a lower portion of said head; and
an electrically conducting member disposed in electrically conducting contact with a portion of the electrode stud upon attachment of said electrode connector to the electrode stud, wherein, upon attachment of said electrode connector to said electrode stud, said lip urges said electrode stud into contact with a bottom surface of said electrically conducting member.

US Pat. No. 10,506,934

OPTICAL FIBER PRESSURE SENSOR

Phyzhon Health Inc., Ran...

1. An apparatus comprising:an elongated assembly, at least a portion of which is sized, shaped, or otherwise configured to be inserted into a human body to measure a pressure at an internal location within the human body, wherein the elongated assembly includes:
a guidewire including a solid core wire having an outer surface and a length, a portion of the outer surface defining a groove extending along a portion of the length of the core wire, the core wire including:
a first portion having a first diameter and a second portion having a second diameter, wherein the second diameter is greater than the first diameter, and wherein the second portion defines a cradle sized and arranged to receive an optical fiber pressure sensor;
an optical fiber positioned within the groove and extending longitudinally along the guidewire, the optical fiber configured to communicate light between a location outside of the human body and a portion of the optical fiber that is to be located at or near the internal location within the human body at which the pressure is to be measured; and
the optical fiber pressure sensor coupled to the optical fiber and configured to be located on the elongated assembly to allow positioning at or near the internal location within the human body at which pressure is to be measured.

US Pat. No. 10,506,917

ENDOSCOPE AND ENDOSCOPE SYSTEM WITH TRANSMISSION BUFFER

OLYMPUS CORPORATION, Tok...

1. An endoscope configured to operate with a power supply voltage supplied from a processing device connected to the endoscope through a transmission cable, the endoscope comprising:a first chip including:
an imaging sensor; and
a first buffer configured to output an imaging signal generated by the imaging sensor; and
a second chip including a second buffer configured to amplify the imaging signal being outputted from the first buffer and output the amplified imaging signal to the transmission cable,
wherein the first buffer is configured to apply a predetermined voltage to the second buffer during a period in which the output of the imaging signal from the first buffer is stopped to cause the second buffer to output a direct current at a predetermined level to the transmission cable.

US Pat. No. 10,506,912

DISHWASHER APPLIANCE WITH VENT DUCT MIXING

Haier US Appliance Soluti...

1. A dishwasher appliance, comprising:a tub defining a wash chamber;
a door mounted to the tub;
a vent duct positioned within the door, a tub channel and an ambient channel positioned within the vent duct such that the tub channel is separate from the ambient channel, an inlet of the tub channel positioned in fluid communication with the wash chamber when the door is closed, an inlet of the ambient channel positioned in fluid communication with ambient air about the tub,
an insert positioned within the vent duct, the insert and the vent duct collectively defining an outlet of the tub channel and an outlet of the ambient channel, the insert positioned between the outlet of the tub channel and the outlet of the ambient channel along a transverse direction,
wherein the outlet of the tub channel has a width along a lateral direction that is perpendicular to the transverse direction, the outlet of the ambient channel has a width along the lateral direction, and the width of the outlet of the tub channel is about equal to the width of the outlet of the ambient channel.

US Pat. No. 10,506,909

DISH WASHER

SAMSUNG ELECTRONICS CO., ...

1. A dishwasher in which dishes are containable, comprising:a main body;
a washing tub provided in the main body;
a door configured to close or open a first side of the washing tub;
a fixed nozzle fixed on a second side of the washing tub and configured to spray water;
a vane configured to be movable along a linear axis within the washing tub and to reflect the water sprayed from the fixed nozzle toward dishes contained in the dishwasher while the vane is being moved along the linear axis within the washing tub; and
a rail assembly extending along the linear axis and configured to guide movement of the vane along the linear axis,
wherein the vane is rotationally coupled to the rail assembly with an axis of rotation of the vane being substantially perpendicular to the linear axis, so that the vane rotates on the axis of rotation to change a direction of the reflected water.

US Pat. No. 10,506,908

BATCH-TYPE WAREWASHER WITH ENERGY RETAINING CURTAIN

ILLINOIS TOOL WORKS INC.,...

14. A batch-type warewash machine for washing wares, comprising:a chamber for receiving wares to be cleaned, the chamber having a chamber access opening and a single spray zone, with at least one spray system for spraying liquid onto wares in the single spray zone, wherein the chamber access opening runs vertically, wherein the chamber lacks any ware conveyance structure that moves wares during cleaning cycles;
a door movable between a closed position covering the chamber access opening and an open position away from the chamber access opening to allow wares to be moved in and out of the chamber, wherein the door is in a vertical orientation when in the closed position;
a curtain structure mounted on the machine, the curtain structure located behind and adjacent a back side of the door when the door is in the closed position, the curtain structure remaining in position and at least partially covering the chamber access opening when the door is in the open position so as to retain hot moist air within the chamber when the door is moved to the open position upon completion of a ware cleaning cycle.

US Pat. No. 10,506,907

DISHWASHER WITH CONTROLLED DRY CYCLE

Whirlpool Corporation, B...

1. A dishwasher, comprising:a tub at least partially defining a treating chamber;
a closed loop condensation system including a dry air conduit having a portion in overlying relationship with a portion of a moist air conduit and where the dry air conduit is fluidly separate from the treating chamber and the moist air conduit, and where the moist air conduit is fluidly coupled to the treating chamber, and where overlying portions of the moist air conduit and the dry air conduit are configured to form a heat exchanger, and the heat exchanger is configured to precipitate moisture from treating chamber air in the moist air conduit;
a first temperature sensor within the dry air conduit of the closed loop condensation system upstream of the heat exchanger or operably coupled to the portion of the dry air conduit that is in overlying relationship with the portion of the moist air conduit and outputting a signal indicative of an external air temperature value;
a second temperature sensor outputting a signal indicative of a temperature of the treating chamber air to define a treating chamber air temperature;
a fan having a first stage fluidly coupled to the moist air conduit and configured to pull moist air from the treating chamber into the moist air conduit to define a circulation; and
a controller operably coupled to the first temperature sensor, second temperature sensor, and the fan, the controller configured to receive the signal indicative of an external air temperature value, receive the signal indicative of the treating chamber air temperature, determine a difference value indicative of a temperature difference between the external air temperature value and the treating chamber air temperature, set a circulating time based on the difference value and operate the fan to circulate the treating chamber air through the moist air conduit and the heat exchanger and back through the treating chamber in the closed loop condensation system for the circulating time while supplying external air over the heat exchanger while the heat exchanger removes liquid from the circulating treating chamber air.

US Pat. No. 10,506,904

HANDHELD SURFACE CLEANING APPARATUS

Omachron Intellectual Pro...

1. A surface cleaning apparatus comprising:(a) an air flow path extending from a dirty air inlet to a clean air outlet;
(b) an air treatment member positioned in the air flow path; and
(c) a removable pre-motor filter assembly positioned downstream of the air treatment member and upstream of a suction motor, the pre-motor filter assembly comprising a pre-motor filter and a filter support member, the filter support member having an outlet conduit which comprises a terminal end that terminates at an outlet port, wherein the terminal end comprises a linear extension of the outlet conduit, and wherein the outlet port of the terminal end extends at a first angle to a direction of air flow through the outlet conduit.

US Pat. No. 10,506,893

CHAI TEA BREWER

InnovaHive Product Develo...

1. An automatic tea brewing system, comprising:a first container configured to hold a first liquid;
a second container configured to hold a second liquid;
a brew pot fluidly coupled to the first container and to the second container;
tea leaves positioned in the brew pot for brewing tea when the brew pot is heated;
a first valve in fluid connection with an outlet of the first container and an inlet of the brew pot, the first valve having an open configuration to permit a flow of the first liquid from the first container to the brew pot and a closed configuration that does not permit the flow of the first liquid from the first container to the brew pot; and
a second valve in fluid connection with an outlet the second container and the inlet the brew pot, the second valve having an open configuration to permit a flow of the second liquid from the second container to the brew pot and a closed configuration that does not permit the flow of the second liquid from the second container to the brew pot;
wherein the system is configured to have the first valve in the open configuration of the first valve to dispense the first liquid from the first container to the brew pot at a first time, to then heat the first liquid in the brew pot to a first temperature, to then have the second valve in the open configuration of the second valve to dispense the second liquid from the second container to the brew pot at a second time later than the first time to produce a liquid mixture of the first liquid and the second liquid in the brew pot with the tea leaves, to then heat the liquid mixture in the brew pot to a second temperature, and, at a third time later than the second time, to then decrease the temperature of the liquid mixture.

US Pat. No. 10,506,892

VESSEL FOR TRANSFERRING THERMAL ENERGY TO AND INDUCING CONVECTION IN A CONTAINED FLUID

1. An article of manufacture comprising:a wall portion having a wall inner surface and a wall outer surface;
a base portion having a base inner surface and a base outer surface, at least a portion of the wall portion and the base portion forming a vessel to retain fluid therein, at least part of the base portion configured to receive heat from a heating source; and
a plurality of shaped portions extending above the base inner surface or the wall inner surface, a top of each of the plurality of shaped portions being opposite a bottom of each of the plurality of shaped portions, the plurality of shaped portions of the base inner surface and/or the inner wall surface being shaped to have 1.2 or more times surface area than a surface of the corresponding flat surface, each shaped portion of the base inner surface including at least three sides extending from the bottom to the top, the top of each of the plurality of shaped portions being hexagonal in shape, each of the plurality of shaped portions capable of supplying heat from the sides to fluid adjacent to the sides of at least one other shaped portion of the plurality of shaped portions, the plurality of shaped portions of the base inner surface or the wall inner surface including the hexagonal shaped tops of the plurality of shaped portions and sides of the plurality of shaped portions to assist in uneven heat transfer from the heating source to the fluid retained in the article of manufacture.

US Pat. No. 10,506,878

CONTAINER STORAGE RACK APPARATUS

1. A storage rack for holding a plurality of containers, the storage rack comprising:a body extending vertically along a longitudinal axis, the body having a first lateral side defining a first major surface opposite a second lateral side defining a second major surface; and
a plurality of container mounting apertures extending through the body from the first major surface to the second major surface;
the plurality of mounting apertures being spaced apart and arranged in a linear array extending along the longitudinal axis;
each of the apertures configured to receive a narrowed neck portion of one of the containers therethrough;
wherein the containers are supported by the neck portion in a cantilevered manner from the body by the mounting apertures;
wherein each mounting aperture includes an asymmetrically shaped wall surface at a first end of the aperture, and a symmetrically shaped cylindrical wall surface at an opposite second end of the aperture; and
wherein the asymmetrical shaped wall surface defines an elongated obround entrance opening at the first end of each mounting aperture, and the cylindrical wall surface defines a circular exit opening at the second end of the mounting aperture, the obround opening being larger than the circular opening in cross-sectional area to facilitate inserting the neck portion of the container therethrough.

US Pat. No. 10,506,876

SELF-ASSEMBLY CABINET

E-MAKE Co., Ltd., Taichu...

1. A self-assembly cabinet comprising:a box including a rectangular front frame, a rectangular rear frame, two rectangular side frames interconnecting the front frame and the rear frame, a top frame on tops of the front frame, the rear frame, and the side frames, and a bottom frame on bottoms of the front frame, the rear frame, and the side frames;
a plurality of latches secured to four corners of an inner surface of each side frame respectively; and
a plurality of cooperating fastening structures secured to four corners of an inner surface of each of the front frame and the rear frame respectively;
wherein the latches are releasably secured to the cooperating fastening structures respectively so that the side frames, the front frame, and the rear frame are configured to assemble;
wherein each latch includes an extension having a concave member and a hook at an open end, and a plate member being at an angle of 90-degree with respect to the extension and threadedly secured to the side frame;
wherein each cooperating fastening structure includes a plate element threadedly secured to the rear frame or the front frame, a cylindrical member projecting out of the plate element, and an enlargement at an open end of the cylindrical member; and wherein the concave member is put on the cylindrical member and the enlargement is configured to prevent the concave member from being disengaged from the cylindrical member.

US Pat. No. 10,506,871

COLLAPSIBLE, SURFACE-MOUNTED APPARATUS

Justin R. Wilson, Denver...

1. A method of operating a surface-mounted apparatus, comprising:rotating first and second planar sections of an apparatus about a first pivot axis oriented normal to the surface that extends through the first section of the apparatus and into the surface; and
pivoting, simultaneously with and induced by the rotating, the second planar section of the apparatus relative to the first planar section of the apparatus about a second pivot axis that is perpendicular to the first pivot axis from a stowed position against the surface into a deployed position extending from the surface.

US Pat. No. 10,506,868

SPORTING WEAPON BACKPACK

1. A sporting weapon backpack comprising:a folding protective cover having an exterior surface and a first side, said folding protective cover being sized to protect the majority of a sporting weapon;
at least one bag compartment attached to the exterior surface of a second side of the folding protective cover, said bag compartment being selectively closed by a zipper, a strap and buckle, a clasp and strap, or hook and loop fasteners;
at least one temporary fastener attached to a peripheral edge of both sides of the folding protective cover, wherein the at least one temporary fastener is adapted to temporarily fasten one peripheral edge of the folding protective cover to the other peripheral edge of the folding protective cover;
at least one pouch attached near the bottom of the interior surface of at least one side of the folding protective cover, wherein the at least one pouch is adapted to support at least a portion of the sporting weapon, wherein the at least one temporary fastener is adapted to close the folding protective cover over the at least one pouch to securely hold and transport the sporting weapon,
wherein the at least one pouch comprises an openings and a bottom portion coupled with the interior surface of at least one side of the folding protective cover, wherein the bottom portion is adapted to support at least a portion the sporting weapon.

US Pat. No. 10,506,866

COSMETIC CONTAINER

AMG CO., LTD., Tokyo (JP...

1. A cosmetics container comprising:a container body which holds a cosmetic material; and
a cap which engages with the container body, wherein the container body includes:
a main body screw portion which engages with the cap;
a main body upper portion formed continuously below the main body screw portion;
a main body middle portion formed continuously below the main body upper portion; and
a main body lower portion formed continuously below the main body middle portion,
the main body upper portion, the main body middle portion and the main body lower portion form a front wall part, a back wall part, a right side wall part, a left side wall part, and a bottom wall part, which collectively form a space which holds the cosmetic material,
the right side wall part and the left side wall part defined by a shape of an inside of the container body are formed such that a thickness at the main body upper portion is thicker than a thickness at the main body middle portion,
the front wall part and the back wall part defined by the shape of the inside of the container body are formed such that portions connecting sideways to the right side wall part and the left side wall part in the main body lower portion are thinner than in the main body middle portion, and
connecting portions between the front wall part and the right side wall part and the left side wall part and connecting portions between the back wall part and the right side wall part and the left side wall part in an inner surface of the main body lower portion are formed as curved surfaces.

US Pat. No. 10,506,863

TOILETRY APPLICATOR

Tessy Plastics Corporatio...

1. A toiletry applicator comprising:a housing;
a screw comprising a screw shaft and a screw knob coupled to the screw shaft; and
an elevator assembly received at a base of the screw shaft and comprising:
a receptacle configured to retain a toiletry, the receptacle having a thread path; and
a plurality of discs stacked together to form a disc assembly defining the thread path, each disc comprising a plurality of thread portions that form a section of the thread path.

US Pat. No. 10,506,861

2-IN-1 NAIL LAMP STATION

1. A nail lamp station, comprising:a base lamp assembly which comprises a station housing, which has a light cavity capable of receiving one or more fingernails therewithin and an opening communicating said light cavity with outside, and a first light source supported and supplied with electrical power in said station housing for illuminating within said light cavity for selectively drying nail polishes on fingernails or curing artificial nail tip attached on the fingernails at the same time within said light cavity, wherein said station housing of base lamp assembly further has a holding compartment provided thereon; and
a detachable lamp pen detachably coupled at said holding compartment of said station housing, wherein said detachable lamp pen comprises an elongated pen body having a shape and size adapted to be retained in said holding compartment, a battery, and a second light source provided at a light end of said pen body and electrically connected with said battery for electrical power supply, wherein said detachable lamp pen is detachable from said holding compartment and switched on said second light source for applying light pointing at a particular area of one single particular fingernail for selectively drying a nail polish on the one single particular fingernail or curing the artificial nail tip attached on the one single particular fingernail.

US Pat. No. 10,506,839

PROTECTIVE HEADGEAR

GUARDIAN INNOVATIONS, LLC...

1. An apparatus to protect a head, comprising:at least one padded section defining a front opening and comprising padding configured to conform to a shape of a head of a wearer;
a mesh section coupled to the at least one padded section;
an adjustable back opening defined by one or more of the mesh section or the at least one padded section; and
an adjustment member configured to removably attach to the one or more of the mesh section or the at least one padded section to allow adjustment of a size of the back opening in at least two directions.

US Pat. No. 10,506,834

ELECTRONIC CIGARETTE AND ATOMIZER DEVICE THEREOF

SHENZHEN SMOORE TECHNOLOG...

1. An atomizer device, wherein the atomizer device comprises a housing, a liquid reservoir chamber (115) defined in the housing, and an adjusting valve (13) engaging with the housing; a liquid injection channel (1131) is defined on the housing for injecting liquid solution into the liquid reservoir chamber (115); the adjusting valve (13) is movable between a first position and a second position and keeps connected to the housing while moving relative to the housing; the adjusting valve (13) is able to move to the first position to open the liquid injection channel (1131), and is able to move to the second position to close the liquid injection channel (1131); the atomizer device comprises an air flowing passage (112) and a sealing unit (113) sealing one end of the liquid reservoir chamber (115).

US Pat. No. 10,506,827

ULTRASONIC AUTOMIZATION PIECE, MANUFACTURING METHOD THEREOF, ULTRASONIC AUTOMIZER AND ELECTRONIC CIGARETTE

CHINA TOBACCO HUNAN INDUS...

1. An ultrasonic atomization piece, wherein the ultrasonic atomization piece comprises a ceramic substrate which is provided with an upper silver layer on an upper surface of the ceramic substrate and a lower silver layer on a lower surface of the ceramic substrate; the ceramic substrate, the upper silver layer and the lower silver layer form piezoelectric ceramic, and a glass glaze layer for protecting the upper silver layer is provided on an upper surface of the piezoelectric ceramic; and a tobacco tar adsorption layer is provided on an upper surface of the glass glaze layer to form a piezoelectric ceramic component, and the tobacco tar adsorption layer is used for adsorbing, guiding and transferring tobacco tar.

US Pat. No. 10,506,800

DEVICE AND A METHOD FOR REDUCING THE NUMBER OF EXTERIOR PARASITES ON FISH

SFI Systems IVS, Tilst (...

1. A device for reducing the number of exterior parasites on farmed fish, the device comprising:a hollow cylindrical filter member having a circumference and an interior, the hollow cylindrical filter member at an inlet end comprising an inlet with an inlet circumference and at an outlet end an outlet with an outlet circumference, the hollow cylindrical filter member being provided with holes between the inlet end and the outlet end, the holes allow exterior parasites to pass through the holes of the hollow cylindrical filter member while maintaining fish in the interior;
a first nozzle provided at the inlet end and having a substantially annular slit along the inlet circumference or a first nozzle provided at the outlet end and having a substantially annular slit along the outlet circumference for ejecting a fluid towards a first predefined point in the interior of the hollow cylindrical filter member between the inlet end and the outlet end.

US Pat. No. 10,506,798

ANIMAL NUTRITION SYSTEM AND METHOD

1. A pet feeding system, comprising:a food container storing a volume of pet food, wherein the food container includes a floor, a sidewall extending upwardly from the floor defining an interior of the food container;
a package identification chip attached to the food container; and
a food serving appliance configured to removably receive the food container;
wherein the food serving appliance includes a recessed portion that removably receives the food container;
wherein the food serving appliance includes a single scale positioned to weigh the food container periodically to generate weight data;
wherein the food serving appliance includes a chip reader that communicates with the package identification chip to receive food container data from the package identification chip, wherein the food container data is combined with the weight data to determine the nutritional consumption of a pet.

US Pat. No. 10,506,769

AGRICULTURAL MOTOR VEHICLE

1. An agricultural motor vehicle, comprising:a monoblock chassis (1), forming a rectangular box having a front section, a rear section; a front panel (21), a rear panel (22), two side panels (24), and a central intermediate panel (23) defining two intermediate spaces (2a); and having upper edges folded crosswise towards an inner side, forming complementary profiles (25) configuring an upper assembly plane (2b) and a lower assembly plane (2c); the chassis supported over four traction wheels, with a front wheel set having two larger independent front wheels (3) and a rear wheel set having two smaller rear wheels (4), the rear wheels having a corresponding axis (5);
a vibrating screen (6) located at an internal lower side of the chassis, forming a platform, the vibrating screen extending along the entire lower assembly plane to an edge of the chassis (1);
a first double rotating cleaning set (7), assembled above the vibrating screen, comprising two lengthwise tunnels extending along an entire length of the vibrating screen (6);
a second rotating set forming a concentrating guiding roller (8), assembled crosswise upon the front section of the chassis (1), the guiding roller comprising a crosswise tunnel having a front inlet opening (9) and a rear outlet opening (10), wherein the rear outlet opening is connected to the rotating cleaning set (7);
a hydraulic activation and transmission set (11), assembled above the concentrating guiding roller (8) and coupled for activation of the rotating cleaning set (7); comprising a support platform for a cockpit (12), the cockpit having a side door, with access to the cockpit provided by a passageway (13) and a ladder (14) located over and above the front left wheel;
a ventilation box (15) for expelling of clean residues, assembled at a rear end of the rotating cleaning set (7);
two impeller sets for an outlet of residues (16), one impeller set assembled along each lower side edge of the ventilation box (15);
a collecting gutter for clean grain (17) assembled at a rear end of the vibrating screen (6), the collecting gutter extending crosswise along the entire rear length of the screen;
two cup elevators (18), each cup elevator located next to and linked to a side edge of the collecting gutter for clean grain (17), the cup elevators slightly forwardly sloped and having upper edges leading to an inside of a dumper (19) for grain storage; the dumper located crosswise over and above the chassis (1); and
a motor power set (20) assembled on a rear side of the ventilation box (15).
US Pat. No. 10,507,217

METHODS AND COMPOSITIONS FOR BOWEL CLEANSING BEFORE A MEDICAL PROCEDURE

The General Hospital Corp...

1. A method of preparing a subject for a colonoscopy, the method comprising providing to a subject in need thereof a plurality of food items comprising solid foods or liquid foods for meals to be ingested by the subject between 24 hours and 2 hours immediately prior to the colonoscopy, wherein at least one meal comprises both low fiber solid foods and liquid foods, and each meal comprises at least one food item having incorporated therein 17-255 grams of polyethylene glycol, sufficient to induce in the subject the production of watery yellow stools with a light yellow effluent within about 6-8 hours of the ingestion of the first meal.
US Pat. No. 10,507,225

POWDER FOR REGULATING INTESTINAL FLORA AND PROTECTING GASTRIC MUCOSA, PREPARATION METHOD AND USE THEREOF

INFINITUS (CHINA) COMPANY...

1. A method for regulating intestinal flora and protecting gastric mucosa, comprising administering an effective amount of a powder to a subject in need thereof,wherein the powder is consisted of xylooligosaccharide, isomaltooligosaccharide, mannitol, inulin, RADIX CODONOPSIS, FRUIT BODY HERICIUM ERINACEUS extract, RHIZOMA DIOSCOREA OPPOSITA, SCLEROTIUM PORIA, SEMEN DOLICHOS, PERICARPIUM CITRUS, FRUCTUS AMOMUM and RHIZOMA ATRACTYLODIS MACROCEPHALAE,
wherein the mass ratio of inulin, xylooligosaccharide, isomaltooligosaccharide, mannitol, RADIX CODONOPSIS, FRUIT BODY HERICIUM ERINACEUS extract, RHIZOMA DIOSCOREAa OPPOSITA, SCLEROTIUM PORIA, SEMEN DOLICHOS, PERICARPIUM CITRUS, FRUCTUS AMOMUM and RHIZOMA ATRACTYLODIS MACROCEPHALAE is 20:10:20:20:4:4:4:4:3:3:3:3.
US Pat. No. 10,507,229

CYCLOSPORIN COMPOSITIONS

Saint Regis Mohawk Tribe,...

1. A method of treating dry eye disease comprising administration of an ophthalmically acceptable emulsion comprising about 0.1% by weight cyclosporin A, about 0.2% by weight castor oil, polyethylene oxide 40 stearate, and a cellulose derivative selected from the group consisting of hydroxypropylmethyl cellulose and carboxymethyl cellulose to a patient in need thereof.
US Pat. No. 10,508,253

PROCESS FOR PREPARING POLYUREA MICROCAPSULES WITH IMPROVED DEPOSITION

Firmenich SA, Geneva (CH...

1. A process for the preparation of core-shell microcapsules comprising the following steps:a) dissolving at least one polyisocyanate having at least two isocyanate groups, in a perfume to form an oil phase;
b) dispersing the oil phase obtained in step a) into an aqueous solution comprising an emulsifier to form an oil-in-water emulsion;
c) adding, sequentially, to the oil-in-water emulsion obtained in step b) a polymeric cross-linker bearing amino groups with a molecular weight equal or higher than 2 000 g/mol chosen from the group consisting of a polyvinylamine, a polyethyleneimine, a polyaminoethylacrylate and mixtures thereof, followed by a polyamine with a molecular weight lower than 250 g/mol selected from the group consisting of 1,2-diaminopropane, 1,2-diaminoethane, diethylenetriamine, guanidine, water soluble guanidine salts, tris-(2-aminoethy)amine, N,N,N?,N?-tetrakis(3-aminopropyl)-1,4-butanediamine, N,N?-bis(3-aminopropyl)-ethylenediamine, and 3,5-diamino-1,2,4-triazole, to form a microcapsule slurry.
US Pat. No. 10,507,230

COMPOSITION HAVING TISSUE-REPAIRING ACTIVITY, AND USE THEREFOR

TOKUSHIMA UNIVERSITY, To...

1. A method for promoting tissue repair comprising administering to a subject in need thereof a component comprising an extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), the component not having a cytoplasmic domain of Siglec-9.
US Pat. No. 10,507,239

V1/V2 FRAGMENTS OF A HIV-1 ENVELOPE GLYCOPROTEIN

The Regents of the Univer...

1. A method for producing a V1/V2 fragment of a HIV-1 envelope glycoprotein gp120 for use in eliciting broadly neutralizing antibodies, wherein the V1/V2 fragment binds to the broadly neutralizing PG9 monoclonal antibody (MAb), the method comprising:expressing the V1/V2 fragment in a cell line lacking an N-acetylglucosaminyltransferase I (GnTI) enzyme activity, wherein the V1/V2 fragment comprises mannose-5 glycans and comprises the amino acid sequence as set forth in SEQ ID NO: 16.
US Pat. No. 10,509,033

METHOD, KIT AND BIOMARKER FOR DIAGNOSING CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY

Kyushu University, Nation...

1. A method for diagnosing and treating chronic inflammatory demyelinating polyneuropathy in a subject, said method comprising:a. obtaining a sample from the subject,
b. determining if the sample contains an anti-neurofascin 155 antibody that is predominantly IgG4,
c. diagnosing the subject with delay of nerve conduction in distal portions and nerve roots of peripheral nerves, hypertrophy of proximal portions and nerve roots of peripheral nerves, and increased cerebrospinal fluid protein levels as compared to the case where the anti-neurofascin 155 antibody is negative if the anti-neurofascin 155 antibody is present in the sample, and
d. administering an effective amount of a drug for treating chronic inflammatory demyelinating polyneuropathy to the diagnosed subject.
US Pat. No. 10,508,271

TARGETED MUTATIONS

GREEN BIOLOGICS LIMITED, ...

1. A process for producing a mutation in an Intended Mutagenesis Region (IMR) within a bacterial genome, wherein the bacteria are of the class Clostridia, wherein the bacteria comprise a CRISPR/Cas system, and wherein the IMR comprises a CRISPR PAM/Protospacer which is capable of being recognised by the bacteria's CRISPR/Cas systems, the process comprising the steps:(a) transforming a population of said bacteria with a Recombination Vector, wherein the Recombination Vector comprises a Recombination Element, wherein the Recombination Element comprises:
(i) a Substitution Element, wherein the Substitution Element comprises the mutation, and
(ii) Homology Arms which flank the Substitution Element, wherein the Homology Arms are capable of promoting the replacement of all or part of the IMR in the bacterial genome with an element which comprises the Substitution Element,
wherein the Recombination Element does not comprise a CRISPR PAM/Protospacer which is capable of being recognised by a crRNA which recognises the CRISPR/PAM Protospacer in the IMR;
(b) culturing the population of bacteria under conditions wherein, in one or more bacteria within the population, all or part of the IMR in the genomes of those bacteria is replaced by an element which comprises the Substitution Element and whereby the CRISPR PAM/Protospacer is removed from the IMR in the genomes of those bacteria or is rendered incapable of being recognised by a crRNA which recognises the CRISPR/PAM Protospacer in the IMR;
(c) transforming the population of bacteria with a Killing Vector which is capable of directing production of a crRNA which targets the CRISPR PAM/Protospacer in the IMR of any bacteria in the population from which the CRISPR PAM/Protospacer has not been removed or rendered incapable of being recognised by the crRNA, thereby promoting the CAS endonuclease-induced cleavage of those CRISPR PAM/Protospacers in the genomic DNA which are recognised by the crRNA and the subsequent death of those bacteria; and
(d) selecting or isolating one or more bacteria from the population whose genomes comprise the Substitution Element comprising the mutation.
US Pat. No. 10,507,261

PASTY TWO-COMPONENT POLYMETHACRYLATE BONE CEMENT

HERAEUS MEDICAL GMBH, We...

1. Pasty two-component polymethacrylate bone cement comprising a pasty component A, comprising:AI at least one distillable methacrylate monomer for radical polymerisation;
AII at least one polymer that is soluble in AI;
AIII at least one particulate polymer with a particle size of no more than 500 ?m that is not soluble in AI;
AIV at least one radical stabiliser; and
AV at least one accelerator from the group of aromatic amines;
and
a pasty component B, consisting of:
BI dibenzoyl peroxide; and
BII at least one substance that is not subject to radical polymerisation and is liquid at room temperature, whereby the solubility of dibenzoyl peroxide in this substance at room temperature is less than 5.0% by weight; and
optionally at least one color pigment that is insoluble in liquid substance BII; and
whereby the weight fraction of liquid substance BII in the self-curing cement dough thus formed after the mixing of pasty component A with pasty component B is completed is less than 2.0% by weight.
US Pat. No. 10,508,295

GAMMA GLUTAMYL-VALINE SYNTHASE, AND METHOD FOR PRODUCING GAMMA GLUTAMYL-VALYL-GLYCINE

AJINOMOTO CO., INC., Tok...

1. A method for producing ?-Glu-Val-Gly and/or a salt thereof, the method comprising:contacting a protein and glutathione synthetase with Glu, Val, and Gly to produce ?-Glu-Val-Gly; and
collecting the produced ?-Glu-Val-Gly,
wherein the protein comprises an amino acid sequence having at least 97% sequence identity to the amino acid sequence of SEQ ID NO: 6, 10, or 16, and has ?-glutamylvaline synthetase activity, and
a ratio of ?-glutamylvaline synthetase activity of the protein to ?-glutamylglycine synthetase activity of the protein is 15 or higher.
US Pat. No. 10,508,302

CONTROL PREPARATION FOR FISH METHODS IN MICROBIOLOGY

CHARITE UNIVERSITATSMEDIZ...

1. A control preparation for use in a method for detection of a target microorganism in microbiological pathology,characterized in that
the control preparation comprises a plurality of section bodies, wherein the section bodies are joined by a joining polymer, and wherein each section body comprises a matrix polymer, and wherein
(a) a first section body comprises a first nucleic acid sequence, which is 100% identical to a nucleic acid sequence comprised in the target microorganism;
(b) a second section body comprises a second nucleic acid sequence, which in comparison to said first nucleic acid sequence, contains a deletion, an additional nucleotide or a different nucleotide in one, two, three or four positions of said second nucleic acid sequence;
wherein said joining polymer and said matrix polymer comprise, or are made of, a polymethacrylic acid alkyl ester,
and wherein the control preparation is positioned on a microscopic sample holder and each section body is positioned within the control preparation so that the identity of the section body can be identified unambiguously by its position relative to
(i) a shape of the control preparation;
(ii) a shape of said sample holder and/or
(iii) a reference point disposed on said sample holder.
US Pat. No. 10,508,303

WHOLE-GENOME AND TARGETED HAPLOTYPE RECONSTRUCTION

LUDWIG INSTITUTE FOR CANC...

1. A method for haplotyping one or more chromosomes of a eukaryotic organism, the method comprising:providing a cell of the organism that contains a set of chromosomes having genomic DNA;
incubating the cell or the nuclei thereof with a fixation agent for a period of time to allow crosslinking of the genomic DNA in situ and thereby to form crosslinked genomic DNA;
fragmenting the crosslinked genomic DNA;
ligating the proximally located crosslinked and fragmented genomic DNA to form a proximally ligated complex having a first genomic DNA fragment and a second genomic DNA fragment,
wherein the first genomic DNA fragment and the second genomic DNA fragment are on the same chromosome, and
wherein the first genomic DNA fragment and the second genomic DNA fragment are apart in situ by at least 100 bp;
shearing the proximally ligated complex to form proximally-ligated DNA fragments;
obtaining a plurality of the proximally-ligated DNA fragments to form a library;
sequencing the plurality of the proximally-ligated DNA fragments to obtain a plurality of sequence reads and
assembling the plurality of sequence reads to construct a haplotype for one or more of the chromosomes.