US Pat. No. 10,364,437

PLANT GENES INVOLVED IN NITRATE UPTAKE AND METABOLISM

Iowa State University Res...

1. A method of expressing a nucleic acid molecule up-regulated by nitrogen in a plant, said method comprising:providing a transgenic plant or plant cell transformed with a nucleic acid construct, wherein the nucleic acid construct comprises:
a nucleic acid molecule that is up-regulated in corn by nitrogen;
a 5? DNA promoter sequence, wherein the DNA promoter sequence is a nitrogen inducible plant promoter; and
a 3? terminator sequence, wherein the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively linked to permit transcription of the nucleic acid molecule, and wherein the nucleic acid molecule:
(a) encodes a polypeptide having the amino acid sequence of SEQ ID NO:43; or
(b) comprises the nucleotide sequence of SEQ ID NO:42; or
(c) comprises the coding portion of the nucleotide sequence of SEQ ID NO:42; and
growing the transgenic plant or a plant grown from the transgenic plant cell under conditions effective to express the nucleic acid molecule in said transgenic plant or said plant grown from the transgenic plant cell.
US Pat. No. 10,364,184

MANUFACTURING METHOD OF BIG-MODEL LOW-PERMEABILITY MICROCRACK CORE

SOUTHWEST PETROLEUM UNIVE...

1. A manufacturing method of a big-model low-permeability microcrack core, comprising the following steps successively:(1) determining a size of a microcrack core to be manufactured;
(2) placing a plurality of stones in a baking oven to bake for 24 h under 120° C., after baking, placing the plurality of stones into a mixer, mixing and spraying an oil, and keeping the mixture of the plurality of stones and the oil for 2 h after mixing evenly to enable the oil to seep into the plurality of stones and evenly forming a layer of thin oil film on a surface of the plurality of stones;
(3) mixing the plurality of stones sprayed by the oil in step (2) with a quartz sand and a cement, and then adding water and mixing evenly to obtain a cement paste;
(4) spreading a butter on an inner surface of a core mould to form a layer of thin butter film on the inner surface of the core mould, pouring the cement paste in step (3) into the core mould, and vibrating the cement paste in the core mould by a vibrating rod during pouring to obtain a cement sample;
(5) loading a predetermined confining pressure outside the core according to a degree of porosity of the mould and the permeability after pouring, so as to adjust a pore permeability value; and
(6) forming the big-model low-permeability microcrack core after drying the cement sample.
US Pat. No. 10,364,442

CRISPR ENABLED MULTIPLEXED GENOME ENGINEERING

The Regents of the Univer...

1. A method for tracking a multitude of genome edits in a cell population, comprising:a) introducing into a first population of cells a first vector that encodes:
(i) at least one editing cassette wherein the at least one editing cassette comprises
a) a region homologous to a target region of a nucleic add and comprising a mutation of at least one nucleotide relative to the target region, and
b) a mutation preventing nuclease binding at a protospacer adjacent motif (PAM);
(ii) at least one promoter; and
(iii) a region encoding at least one guide RNA comprising a region complementary to the target region, thereby producing a second population of cells that comprise the first vector;
b) maintaining the second population of cells under conditions n which a nuclease is expressed thereby producing a cell library that comprises a genome edit and comprises the mutation preventing nuclease binding at the PAM; and
c) tracking the multitude of genome edits in the cell library by sequencing the editing cassette of the first vector from at east one cell in the cell library or sequencing the target region of at least one cell in the cell library.
US Pat. No. 10,364,445

PROCESSES OF PRODUCING FERMENTATION PRODUCTS

1. A method of dewatering whole stillage comprising:(a) liquefying a starch-containing material with an alpha-amylase; optionally pre-saccharifying the liquefied material before step (b);
(b) saccharifying the liquefied material;
(c) fermenting using a fermentation organism;
(d) separating the fermented material into a fermentation product and whole stillage;
(e) dewatering the whole stillage;
wherein a carbohydrate-source generating enzyme and a cellulolytic composition comprising a beta-glucosidase having a Relative ED50 loading value of less than 1.00 are present or added during the optional presaccharification step, saccharification step (b), and/or fermentation step (c), or simultaneous saccharification and fermentation, and wherein the beta-qlucosidase is the Aspergillus fumiqatus beta-qlucosidase of SEQ ID NO: 6 or a variant thereof having at least 85% sequence identity to the amino acid sequence of SEQ ID NO: 6 and which comprises one or more substitutions selected from the group consisting of L89M, G91L, F100D, I140V, I186V, S283G, N456E, and F512Y.
US Pat. No. 10,364,192

METHOD FOR FORMING SINTERED CERAMIC MATERIAL

King Fahd University of P...

1. A process for forming a sintered Ca-SiAlON ceramic containing aluminum particles, comprising:mixing
calcium oxide;
silicon nitride;
alumina;
aluminum nitride; and
1.8 wt % to 10 wt % of aluminum particles to form a powder mixture, wherein wt % is based on the total weight of the powder mixture;
spark plasma sintering the powder mixture under a uniaxial pressure of from 20 to 55 MPa to form the sintered Ca-SiAlON ceramic; and
cooling the sintered Ca-SiAlON ceramic to a temperature ranging from 20-40° C.
US Pat. No. 10,364,449

FERMENTATIVE PRODUCTION OF OLIGOSACCHARIDES

1. A method for producing difucosyllactose, said method comprising the step of culturing, in a culture medium containing an exogenously added acceptor and a genetically modified E. coli of LacY+ genotype having a H. pylori futC gene that encodes an ?-1,2-fucosyl transferase that is (a) capable of modifying said acceptor and (b) is necessary for the synthesis of said difucosyllactose from said acceptor wherein the acceptor consists of 2?-O-fucosyllactose.
US Pat. No. 10,364,450

PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS

EVOLVA SA, Reinach (CH)

1. A recombinant host cell capable of producing a steviol glycoside, a glycosylated ent-kaurenol compound, and/or a glycosylated ent-kaurenoic acid compound in a cell culture, comprising a gene encoding a polypeptide capable of selectively converting rubusoside to stevioside and having 95% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:17 or 18 and a first gene encoding a first polypeptide capable of beta 1,2 glycosylation of the C2? of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of the steviol glycoside and having 95% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:16; wherein the recombinant host cell further comprises one or more of:(a) a second gene encoding a second polypeptide capable of beta 1,2 glycosylation of the C2? of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of the steviol glycoside,
having 95% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:11;
(b) a gene encoding a polypeptide capable of glycosylating steviol or the steviol glycoside at its C-13 hydroxyl group
having 95% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:7; and
(c) a gene encoding a polypeptide capable of beta 1,3 glycosylation of the C3? of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of the steviol glycoside
having 95% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:9; or
(d) a gene encoding a polypeptide capable of glycosylating steviol or a steviol glycoside at its C-19 carboxyl group, wherein the polypeptide comprises a polypeptide having 95% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:4;
wherein at least one of the genes is a recombinant gene.
US Pat. No. 10,364,451

POLYMER CONJUGATES HAVING REDUCED ANTIGENICITY AND METHODS OF USING THE SAME

Duke University, Durham,...

1. A method of reducing the antigenicity of a molecule, the method comprising conjugating at least one branched polymer to a molecule to form a molecule-polymer conjugate,wherein the molecule comprises a polypeptide, a polynucleotide, a small molecule, or a combination thereof,
wherein the branched polymer comprises poly[oligo(ethylene glycol) methyl ether methacrylate] (POEGMA),wherein the POEGMA comprises:a backbone comprising poly(methyl methacrylate); and
a plurality of side chains covalently attached to the backbone, where each side chain comprises 2 to 9 monomers of ethylene glycol (EG) repeated in tandem;
wherein the molecule-polymer conjugate is not reactive with pre-existing anti-PEG antibodies in a subject, and
wherein the molecule-polymer conjugate has reduced or eliminated antigenicity compared to a control.
US Pat. No. 10,364,203

METHOD FOR PREPARING PHENOLICS USING A CATALYST

1. Method for preparing a phenolic compound comprising reacting a furanic compound with a dienophile in the presence of a catalyst comprising yttrium.
US Pat. No. 10,364,466

BIOLOGICAL MARKERS FOR IDENTIFYING PATIENTS FOR TREATMENT WITH VEGF ANTAGONISTS

Genentech, Inc., South S...

1. A method of optimizing therapeutic efficacy of a VEGF antagonist for a patient, the method comprising:(a) detecting expression of at least three genes set forth in Table 2 in a sample obtained from the patient prior to any administration of a VEGF antagonist to the patient;
(b) comparing the expression level of the at least three genes to a reference expression level of the at least three genes, wherein a change in the level of expression of the at least three genes in the patient sample relative to the reference expression level identifies a patient who is likely to respond to treatment with a VEGF antagonist; and
(c) administering a VEGF antagonist to the patient identified in step (b) as likely to respond to treatment with a VEGF antagonist,
wherein the VEGF antagonist is an anti-VEGF antibody and the change in the level of expression of the at least three genes in the patient sample is an increase relative to the reference expression level.
US Pat. No. 10,363,700

BIORIENTED POLYETHYLENE FILM

Dow Global Technologies L...

1. A process for forming a biaxially oriented film comprising the steps of:a. selecting a polyolefin resin, wherein said polyolefin resin comprises a linear low density polyethylene resin characterized by having from 9 to 35 weight percent of the total weight of the linear low density polyethylene resin eluting from a crystallization elution fractionation (CEF) at a temperature greater than 97.0° C., a comonomer distribution ratio (CDR) of from 33 to 80, and a molecular weight ratio (Mw Ratio) of from 0.15 to 0.45;
b. forming a film from the polyolefin resin selected in step (a); and
c. biaxially orienting the film formed in step (b),
wherein the resulting film after said orienting in step (c) is characterized by having an ultimate elongation which is at least 1.5 times greater in the machine direction (MD) of the film as compared to the cross direction (CD) of the film and a 2% secant modulus of at least 1.25 times greater in the CD as compared to the MD,
wherein the resulting film after said orienting in step (c) is further characterized by having free residual shrinkage of less than 10% in the MD and less than 10% in the CD when exposed to a temperature of 90° C. for 10 minutes,
and wherein the polyolefin resin selected in step (a) permits use of applied temperature and stretching ratio conditions for said orientation step (c) to be chosen within a relatively broad range during the orienting process without a substantial loss in quality of the bioriented film, as compared to a film formed with a polyethylene resin which does not have the CEF, CDR, and Mw Ratio parameters of the polyolefin resin selected in step (a).
US Pat. No. 10,364,214

METHOD FOR PRODUCING ISOCYANATES

Covestro Deutschland AG, ...

15. A plant (10 000) for preparation of an isocyanate (1) by phosgenation of the corresponding amine (2), comprising:0) optionally an apparatus (4000) for production of phosgene (3) by reaction of carbon monoxide (300) with chlorine (310), giving an offgas stream (320) comprising carbon monoxide and phosgene;
I) a reaction zone (1000) comprising a reaction space (1200) for performance of the phosgenation, with a separation unit (1210) optionally connected downstream thereof, where the reaction space or the separation unit are provided with outlet conduits for a liquid stream (60) and a gaseous stream (70);
II) a distillation apparatus (2100) for separating the liquid stream (60) into a liquid stream (80) and a gaseous stream (90);
III) optionally a distillation apparatus (2200) for separating the liquid stream (80) into a gaseous stream (110) and a liquid stream (100);
IV) optionally a distillation apparatus (2300) for separating the gaseous stream (110), optionally after its liquefaction in a condenser (2310), into a liquid stream (120) and a gaseous stream (130);
V) optionally a distillation apparatus (2400) for obtaining a liquid isocyanate stream (140) from the liquid stream (100), resulting in a gaseous stream (150) comprising secondary components and optionally solvent, optionally comprising an upstream unit for polymer removal (2410) for removal of polymeric isocyanate fractions (141);
VI) an apparatus for absorption (2500) of the gaseous streams (70) and (90) and, if present, of the gaseous stream (130), optionally after passing through units (2510) for condensation connected upstream of the apparatus for absorption (2500), in solvent (4) to obtain a liquid stream (160) and a gaseous stream (170);
VII) an apparatus for absorption (2600) of the gaseous stream (170) in water or hydrochloric acid, optionally comprising a vapor condenser (2610), to obtain a stream (190) comprising hydrochloric acid and optionally solvent and a gaseous stream (200) comprising solvent and optionally gaseous secondary components;
VIII) an apparatus for workup of offgas streams (3000), comprising
VIII-1) an apparatus for catalytic phosgene decomposition (3010) for the decomposition of phosgene present in stream (200) and optionally also for the decomposition of phosgene present in stream (320) to obtain a gaseous stream (210) comprising solvent and optionally gaseous secondary components;
VIII-2) an adsorption apparatus (3020) for adsorption of solvent from stream (210), wherein the adsorption apparatus (3020) comprises at least two adsorption units (3021, 3022) connected in parallel, which are configured such that they can alternately be
(i) charged with stream (210) and
(ii) regenerated with steam;
IX) an apparatus for offgas combustion (6000) for combustion of the gas stream (220) obtained in VIII-2) (i); and
X) units for recycling of solvent desorbed in process stage VIII-2) (ii) into the reaction zone (1000) and/or into the apparatus for absorption (2500).
US Pat. No. 10,364,470

LONG NON-CODING RNA EXPRESSED IN AGGRESSIVE CANCER

The Regents of the Univer...

7. A method of detecting the level of expression of an RNA version of the SAILOR sequence SEQ ID NO: 2 in a human tissue sample, wherein the method comprises performing a quantitative reverse transcriptase-PCR (RT-PCR) on RNA obtained from the human tissue sample using amplification oligonucleotides that amplify a fragment comprising at least 700 contiguous nucleotides of SEQ ID NO: 2.
US Pat. No. 10,364,472

METHOD FOR IDENTIFYING WUZHISHAN MINIATURE PIG INBRED LINE BY USING 145 SNPS

1. A method for auxiliarily identifying whether a pig is Wuzhishan miniature pig inbred line, comprising:a) obtaining a DNA sample from the pig;
b) testing a genotype of the pig by hybridizing the DNA sample with each of 145 probes and terminally extending each of the hybridized 145 probes; and
c) identifying the pig to be a candidate for Wuzhishan miniature pig inbred line based on 145 SNP sites if all standards of the following (1) to (145) are satisfied
(1) M1GA0025062 the genotype of SNP site is GG;
(2) DRGA0017627 the genotype of SNP site is GG;
(3) H3GA0056137 the genotype of SNP site is CC;
(4) MARC0039661 the genotype of SNP site is AA;
(5) ASGA0085025 the genotype of SNP site is TT;
(6) ASGA0098570 the genotype of SNP site is GG;
(7) MARC0063358 the genotype of SNP site is AA;
(8) ASGA0085437 the genotype of SNP site is GG;
(9) MARC0096709 the genotype of SNP site is CC;
(10) H3GA0052387 the genotype of SNP site is GG;
(11) ASGA0000264 the genotype of SNP site is TT;
(12) ALGA0000195 the genotype of SNP site is TT;
(13) H3GA0001444 the genotype of SNP site is AA;
(14) ASGA0002293 the genotype of SNP site is CC;
(15) INRA0001752 the genotype of SNP site is GG;
(16) H3GA0001445 the genotype of SNP site is GG;
(17) ALGA0002595 the genotype of SNP site is TT;
(18) ALGA0002600 the genotype of SNP site is GG;
(19) DRGA0000563 the genotype of SNP site is CC;
(20) DRGA0000565 the genotype of SNP site is CC;
(21) INRA0001761 the genotype of SNP site is AA;
(22) MARC0104045 the genotype of SNP site is CC;
(23) ALGA0002601 the genotype of SNP site is CC;
(24) DRGA0000569 the genotype of SNP site is AA;
(25) ALGA0002608 the genotype of SNP site is TT;
(26) DRGA0000568 the genotype of SNP site is CC;
(27) ALGA0002604 the genotype of SNP site is GG;
(28) MARC0048118 the genotype of SNP site is TT;
(29) ASGA0004229 the genotype of SNP site is CC;
(30) MARC0007088 the genotype of SNP site is CC;
(31) MARC0000061 the genotype of SNP site is GG;
(32) MARC0094747 the genotype of SNP site is AA;
(33) MARC0007969 the genotype of SNP site is AA;
(34) ASGA0106092 the genotype of SNP site is CC;
(35) ALGA0119806 the genotype of SNP site is GG;
(36) INRA0003745 the genotype of SNP site is AA;
(37) INRA0003746 the genotype of SNP site is TT;
(38) ALGA0005490 the genotype of SNP site is CC;
(39) H3GA0002538 the genotype of SNP site is CC;
(40) INRA0003749 the genotype of SNP site is CC;
(41) H3GA0002539 the genotype of SNP site is GG;
(42) M1GA0001099 the genotype of SNP site is CC;
(43) MARC0111831 the genotype of SNP site is AA;
(44) ASGA0005566 the genotype of SNP site is CC;
(45) ALGA0007578 the genotype of SNP site is CC;
(46) ASGA0005568 the genotype of SNP site is CC;
(47) INRA0005765 the genotype of SNP site is AA;
(48) MARC0095347 the genotype of SNP site is CC;
(49) MARC0039015 the genotype of SNP site is CC;
(50) DRGA0001892 the genotype of SNP site is GG;
(51) ALGA0007580 the genotype of SNP site is GG;
(52) ALGA0007583 the genotype of SNP site is TT;
(53) MARC0095915 the genotype of SNP site is CC;
(54) ASGA0005571 the genotype of SNP site is AA;
(55) MARC0014134 the genotype of SNP site is AA;
(56) MARC0024233 the genotype of SNP site is AA;
(57) H3GA0003548 the genotype of SNP site is GG;
(58) ALGA0007591 the genotype of SNP site is CC;
(59) MARC0000195 the genotype of SNP site is CC;
(60) ALGA0038697 the genotype of SNP site is CC;
(61) H3GA0020000 the genotype of SNP site is CC;
(62) ALGA0038703 the genotype of SNP site is CC;
(63) H3GA0020002 the genotype of SNP site is GG;
(64) DRGA0007138 the genotype of SNP site is CC;
(65) ASGA0031284 the genotype of SNP site is CC;
(66) ASGA0031285 the genotype of SNP site is AA;
(67) MARC0025042 the genotype of SNP site is GG;
(68) H3GA0020006 the genotype of SNP site is TT;
(69) ALGA0038729 the genotype of SNP site is CC;
(70) ALGA0038731 the genotype of SNP site is GG;
(71) ASGA0031321 the genotype of SNP site is GG;
(72) ASGA0031322 the genotype of SNP site is GG;
(73) ALGA0038747 the genotype of SNP site is AA;
(74) ASGA0033095 the genotype of SNP site is TT;
(75) ALGA0040854 the genotype of SNP site is GG;
(76) ALGA0040856 the genotype of SNP site is AA;
(77) ALGA0040857 the genotype of SNP site is GG;
(78) ASGA0033096 the genotype of SNP site is GG;
(79) INRA0025180 the genotype of SNP site is AA;
(80) ALGA0040859 the genotype of SNP site is CC;
(81) H3GA0021216 the genotype of SNP site is CC;
(82) ASGA0033098 the genotype of SNP site is CC;
(83) H3GA0021221 the genotype of SNP site is CC;
(84) MARC0014540 the genotype of SNP site is CC;
(85) ASGA0033103 the genotype of SNP site is CC;
(86) DIAS0000557 the genotype of SNP site is AA;
(87) ASGA0033116 the genotype of SNP site is AA;
(88) ASGA0036835 the genotype of SNP site is CC;
(89) MARC0031932 the genotype of SNP site is CC;
(90) ASGA0036838 the genotype of SNP site is CC;
(91) H3GA0023523 the genotype of SNP site is GG;
(92) ALGA0045460 the genotype of SNP site is TT;
(93) MARC0005927 the genotype of SNP site is GG;
(94) MARC0005928 the genotype of SNP site is AA;
(95) ASGA0036842 the genotype of SNP site is CC;
(96) ASGA0036846 the genotype of SNP site is CC;
(97) MARC0098637 the genotype of SNP site is TT;
(98) M1GA0011035 the genotype of SNP site is TT;
(99) DRGA0008230 the genotype of SNP site is GG;
(100) ASGA0036855 the genotype of SNP site is CC;
(101) ALGA0097277 the genotype of SNP site is GG;
(102) MARC0080197 the genotype of SNP site is CC;
(103) H3GA0050489 the genotype of SNP site is TT;
(104) ALGA0097281 the genotype of SNP site is TT;
(105) H3GA0050490 the genotype of SNP site is CC;
(106) ALGA0097282 the genotype of SNP site is TT;
(107) ASGA0079089 the genotype of SNP site is CC;
(108) INRA0055354 the genotype of SNP site is GG;
(109) ASGA0079091 the genotype of SNP site is TT;
(110) ASGA0079090 the genotype of SNP site is CC;
(111) H3GA0050491 the genotype of SNP site is AA;
(112) MARC0056017 the genotype of SNP site is TT;
(113) MARC0055759 the genotype of SNP site is AA;
(114) H3GA0050495 the genotype of SNP site is GG;
(115) ALGA0097291 the genotype of SNP site is GG;
(116) ALGA0097290 the genotype of SNP site is GG;
(117) CASI0006683 the genotype of SNP site is GG;
(118) ASGA0079098 the genotype of SNP site is CC;
(119) ALGA0097297 the genotype of SNP site is GG;
(120) H3GA0054426 the genotype of SNP site is TT;
(121) ALGA0098112 the genotype of SNP site is GG;
(122) MARC0089391 the genotype of SNP site is GG;
(123) ASGA0089892 the genotype of SNP site is AA;
(124) ASGA0097792 the genotype of SNP site is CC;
(125) MARC0046857 the genotype of SNP site is GG;
(126) MARC0077194 the genotype of SNP site is AA;
(127) ALGA0108769 the genotype of SNP site is CC;
(128) H3GA0050799 the genotype of SNP site is CC;
(129) ALGA0098120 the genotype of SNP site is CC;
(130) ALGA0098123 the genotype of SNP site is GG;
(131) ALGA0098128 the genotype of SNP site is GG;
(132) ASGA0079719 the genotype of SNP site is CC;
(133) ASGA0079728 the genotype of SNP site is GG;
(134) ASGA0080429 the genotype of SNP site is CC;
(135) MARC0052755 the genotype of SNP site is GG;
(136) ALGA0098918 the genotype of SNP site is GG;
(137) ASGA0080432 the genotype of SNP site is GG;
(138) ALGA0098922 the genotype of SNP site is CC;
(139) INRA0056206 the genotype of SNP site is GG;
(140) INRA0056207 the genotype of SNP site is CC;
(141) ASGA0080435 the genotype of SNP site is CC;
(142) MARC0068495 the genotype of SNP site is GG;
(143) ASGA0080436 the genotype of SNP site is CC;
(144) MARC0003370 the genotype of SNP site is CC;
(145) ASGA0085659 the genotype of SNP site is CC;and, if any standard of the above (1) to (145) is not satisfied, the pig is a candidate for non-Wuzhishan miniature pig inbred line.
US Pat. No. 10,364,474

MICROBIAL MARKERS AND USES THEREFOR

IMMUNEXPRESS PTY LTD, Bo...

1. A method of treating a sepsis-associated bacterial infection in a mammalian subject, the method comprising:1) determining that a subject has an infection with a sepsis-associated Gram positive or Gram negative bacterium by detecting a single nucleotide polymorphism (SNP) in a 16S rRNA gene in nucleic acid from a blood sample from the subject, wherein the SNP is at a position corresponding to position 396 of the 16S rRNA gene set forth in SEQ ID NO:1, and wherein
the bacterium is determined to be a Gram-negative bacterium only when there is a C at position 396 and the bacterium is determined to be a Gram-positive bacterium only when there is an A, T or G at position 396; wherein the bacterium is selected from among Salmonella enterica, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus, Enterococcus faecalis, Enterococcus faecium, Clostridium perfringens, Streptococcus anginosus, Streptococcus constellatus, Streptococcus intermedius, Streptococcus mitis, Streptococcus mutans, Streptococcus sanguinis, Streptococcus sobrinus, Streptococcus oralis, Streptococcus pneumoniae, Streptococcus agalactiae, Streptococcus bovis, Streptococcus sanguinis, Streptococcus dysgalactiae, Streptococcus mutans, Streptococcus pyogenes, Escherichia coli, Acinetobacter baumannii, Bacteroides fragilis, Burkholderia cepacia, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Enterobacter aerogenes, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Citrobacter freundii, Morganella morganii, Haemophilus influenzae, Neisseria meningitidis, Stenotrophomonas maltophila, Prevotella buccae, Prevotella intermedia, Prevotella melaninogenica, Mycobacterium tuberculosis, Streptomyces somaliensis and Streptomyces anulatus; and
2) administering to the subject a therapy when the subject is determined in step 1) to have an infection with a sepsis-associated Gram positive or Gram negative bacterium, wherein the therapy comprises administration of an antibiotic and/or an antibody to endotoxin.
US Pat. No. 10,366,782

METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS, AND THERAPEUTICS FOR CARDIOVASCULAR DISEASE CONDITIONS

uBiome, Inc., San Franci...

1. A method for at least one of characterizing and treating a cardiovascular condition for a subject, the method comprising:providing a sampling kit to the subject associated with the cardiovascular condition, the sampling kit comprising a sample container and a pre-process reagent component, wherein the sample container is operable to receive a sample;
receiving the sample from the sampling kit, the sample comprising a microorganism component;
selecting a primer set for a nucleic acid sequence set associated with the microorganism component;
with a next generation sequencing platform, determining a set of microorganism nucleic acid sequences based on the sample and the primer set;
generating a microbiome feature dataset for the subject based on the set of microorganism nucleic acid sequences;
generating a characterization of the cardiovascular condition based on the microbiome feature dataset;
determining a therapy for the subject based on the characterization, wherein the therapy is operable to improve a state of the cardiovascular condition; and
providing the therapy to the subject associated with the cardiovascular condition, wherein the therapy is operable to modulate microbiome composition to improve the state of the cardiovascular condition.
US Pat. No. 10,363,202

DENTAL MATERIAL INCLUDING PROPYLBARBITURIC ACID POLYMERIZATION CATALYST

SHOFU INC., Kyoto (JP)

1. A dental material comprising a polymerizable monomer, 1-cyclohexyl-5-propylbarbituric acid and trioctylmethylammonium chloride, wherein the polymerizable monomer comprises a (meth)acrylic acid group-containing monomer.
US Pat. No. 10,363,459

GOLF BALL

SUMITOMO RUBBER INDUSTRIE...

1. A golf ball comprising a spherical core and one or more cover layers disposed outside the spherical core, wherein at least one layer of the cover layers contains:(A) a base resin containing (a-1) an ionomer resin and having a material hardness of 58 or less in Shore D hardness; and
(B) a polyrotaxane having a cyclodextrin with at least a part of hydroxyl groups of the cyclodextrin being modified with a caprolactone chain via —O—C3H6—O— group, a linear molecule piercing through a cyclic structure of the cyclodextrin, and blocking groups located at both terminals of the linear molecule to prevent disassociation of the cyclodextrin.
US Pat. No. 10,364,483

HIGH HARDNESS, HIGH ELASTICITY INTERMETALLIC COMPOUNDS FOR MECHANICAL COMPONENTS

The United States of Amer...

1. A material comprising:54-57 atomic percent nickel (Ni);
0.1 up to and including 27 atomic percent of the sum of one or more elements from the group consisting of zirconium (Zr), hafnium (Hf), rutherfordium (Rf), lanthanum (La), and tantalum (Ta); and
a balance of the material being titanium (Ti) by atomic percent, wherein the material has a lower solvus temperature than that of 60-NITINOL, wherein the material possesses a hardness between 56 and 62 on the Rockwell C (HRC) hardness scale.
US Pat. No. 10,363,206

ORAL CARE COMPOSITIONS

Colgate-Palmolive Company...

1. An oral care composition comprising a calcium abrasive, potassium nitrate (KNO3), and a basic amino acid, in free or salt form, wherein the potassium nitrate is present in an amount of 0.3-0.8% by weight of the composition, wherein the composition is a dentifrice, wherein the calcium abrasive is present in an amount of 30-60% by weight of the composition, wherein the basic amino acid, in free or salt form, is present in an amount of 0.1-20% by weight of the composition, wherein the calcium abrasive is calcium carbonate, and wherein the basic amino acid, in free or salt form, is arginine, in free or salt form.
US Pat. No. 10,363,719

MONOAXIALLY ORIENTED MULTILAYER CAST FILM

Borealis AG, Vienna (AT)...

1. A multilayer cast film oriented in machine direction, the multilayer cast film comprises at least three layers A, B and C, whereina) layer A is an outer layer comprising a heterophasic propylene copolymer, wherein the heterophasic propylene copolymer of layer A comprises
a-a) 75 to 95 wt % of a polypropylene matrix (PP-M) with an MFR2 (ISO 1133, 230° C., 2.16 kg) of 0.5 to 30.0 g/10 min being a homopolymer or a copolymer which has a comonomer content of less than 10.0 wt %,
a-b) 5 to 25 wt % of a propylene/alpha-olefin rubber (EPR) with at least 50 wt % propylene having an intrinsic viscosity (IV) of 0.8 to 2.5 dl/g, and
a-c) 0.0001 to 1 wt % of an alpha-nucleating agent (NA);
b) layer B is a core layer comprising a high isotacticity polypropylene homopolymer, wherein the high isotacticity polypropylene homopolymer of layer B is characterized by
(b-i) an isotacticity expressed in mmmm pentads of at least 96 mol %, measured by means of 13 C-NMR,
(b-ii) a decaline soluble content of 2.0 wt % or below, and
(b-iii) polydispersity index (PI) of at least 5.5;
and
c) layer C is a sealing layer comprising a propylene based random copolymer or a propylene based terpolymer, optionally in combination with a heterophasic propylene copolymer, wherein the propylene based random copolymer or terpolymer of layer C comprises
(c-i) 80.0 to 98.0 wt % of propylene,
(c-ii) up to 5.0 wt % of ethylene, and
(c-iii) 1.5 to 20.0 wt % of an alpha-olefin having 4 to 20 carbon atoms,
wherein the sum of (c-i), (c-ii), (c-iii) is 100 wt % and the amount of ethylene (c-ii), if present, is lower than the amount of alpha-olefin (c-iii),
wherein the machine direction oriented multilayer cast film has
(i) a tensile modulus measured according to ISO 527-3 on a 50 ?m film in machine direction of at least 2600 MPa and in transverse direction of at least 1200 MPa,
(ii) a haze value measured according to ASTM D1003 on a 50 ?m film of at most 5.5%, and
(iii) a shrinkage measured according to the method as described in the experimental parton a 50 ?m film after 10 minutes at 100° C. in machine direction of at most ?3.0%.
US Pat. No. 10,364,231

METHOD FOR PRODUCING 2,3,5-TRIMETHYL BENZOQUINONE BY OXIDATION OF 2,3,6-TRIMETHYLPHENOL

BASF SE, (DE)

1. A mixture consisting essentially of 2,3,5-trimethylbenzoquinone, the mixture being prepared by a process consisting essentially of the following step:(i) oxidizing 2,3,6-trimethylphenol to 2,3,5-trimethylbenzoquinone with oxygen or an oxygen-containing gas in a two-phase or multiphase reaction medium in the presence of a catalyst or catalyst system at least comprising a copper(II) halide, to give a mixture comprising 2,3,5-trimethylbenzoquinone,wherein the reaction medium comprises water and at least one secondary aliphatic acyclic alcohol having 6 or more carbon atoms.
US Pat. No. 10,363,208

METHODS FOR IMPROVING THE DURABILITY OF COLOR IN ARTIFICIALLY COLORED HAIR

1. A method for artificially coloring hair and inhibiting the coloring from fading, the method comprising:(a) treating hair with a pre-color treatment composition comprising about 0.1 wt. % to about 50 wt. % of one or more divalent metal salts of an inorganic acid and about 0.1 wt. % to about 50 wt. % of one or more monovalent or divalent metal salts of an organic acid; and
(b) treating the hair with a hair coloring composition comprising one or more colorants chosen from oxidative dye precursors, direct dyes, pigments, and mixtures thereof,
wherein the weight ratio of the one or more divalent metal salts of an inorganic acid to the one or more monovalent or divalent metal salts of an organic acid is from about 10:1 to about 1:10, and
all weights being based on the total weight of the pre-color treatment composition.
US Pat. No. 10,363,210

ORAL CARE COMPOSITIONS

Colgate-Palmolive Company...

1. A toothpaste composition comprising:(i) a whitening complex comprising crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, wherein the whitening complex contains about 10-30% hydrogen peroxide, by weight, and about 5-15% total nitrogen by weight, and
(ii) 25-40% by weight of humectants selected from propylene glycol, glycerin, and combinations thereof;
(iii) 5-15% by weight of polyethylene glycol of average molecular weight 400 to 800 Da;
and wherein the composition comprises 0.5 to 3% of total hydrogen peroxide by weight of the composition, and wherein the composition comprises less than 2% by weight of water; and
(iv) 25-45% by weight of a calcium abrasive.
US Pat. No. 10,363,211

HAIR CONDITIONING COMPOSITIONS COMPRISING LOW VISCOSITY EMULSIFIED SILICONE POLYMERS

The Procter and Gamble Co...

1. A hair conditioning composition comprising:a) a silicone polymer comprising:
i. one or more quaternary groups;
ii. at least one silicone block comprising greater than 200 siloxane units;
iii. at least one polyalkylene oxide structural unit; and
iv. at least one terminal ester group;
wherein said silicone polymer has a viscosity of 500 mPa·s to 100,000 mPa·s at 20° C. at 100% concentration of said silicone polymer with no additional solvents and a shear rate of 0.1 s?1,
wherein said silicone polymer is added to create a pre-emulsified dispersion with a particle size of less than about 1 micron, and
b) a gel matrix comprising:
i. a cationic surfactant;
ii. a high melting point fatty compound, wherein the high melting point fatty compound has a melting point of about 25° C. or higher; and
iii. an aqueous carrier;
wherein said silicone polymer is mixed with said gel matrix.
US Pat. No. 10,363,212

AESCULUS HIPPOCASTANUM EXTRACT

1. A method of improving an appearance of a skin and/or a mucosa, to improve cutaneous strength and/or elasticity, to treat or prevent skin aging, wrinkles, or skin slackening, the method comprising:administering an extract for a cosmetic treatment of the skin and/or mucosa,
said extract being an Aesculus hippocastanum extract obtained by an extraction method comprising:
a solid/liquid extraction step of a flower of Aesculus hippocastanum with a solvent, followed by
a second solid/liquid separation step, and
a third step for recovering the liquid phase,
wherein the solvent consists of a mixture of fructose and glycerin and water.
US Pat. No. 10,363,724

RESIN COMPOSITION AND COMPRESSION-MOLDED ARTICLE OF SAME

Mitsubishi Chemical Corpo...

15. A molded article formed by compression molding the prepreg laminate according to claim 14.
US Pat. No. 10,363,213

IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI

The United States of Amer...

1. A method of inducing an immune response in a mammal against a Campylobacter jejuni strain comprising administering to said mammal an immunogenic composition comprising one or more isolated capsule polysaccharides or polysaccharide polymers derived from Campylobacter jejuni strain HS50; wherein said immunogenic composition does not contain Campylobacter jejuni lipooligosaccharide structures associated with Guillain-Barré Syndrome; wherein said immune response is against a Campylobacter jejuni strain of an HS4 complex selected from the group consisting of Campylobacter jejuni strains HS4, HS13, HS4/13/64, and HS50; wherein the structure of HS4 is [?3)-L-?-D-ido-Hep-(1?4)-?-D-GlcNAc-(1?]n, with non-stoichiometric MeOPN at C-4 of LD-ido-Hep; wherein the structure of HS4/13/64 is [?3)-6d-?-D-ido-Hep-(1?4)-?-D-GIcNAc-(1?]n with non-stoichiometric MeOPN at C-2 and/or C-7 of 6d-ido-Hep; and wherein “n” is 1 to 100.
US Pat. No. 10,365,262

METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION

Johnson Matthey Public Li...

1. A method of monitoring a parameter of a hydrocarbon well, pipeline or formation, the method comprising:introducing a tracer into the hydrocarbon well, pipeline or formation;
producing a fluid from the hydrocarbon well, pipeline or formation; and
analysing the fluid to determine if the tracer is present in the fluid;
wherein the tracer comprises a halogenated alkoxylated-benzoic acid, an alkoxylated benzene sulfonic acid, a salt of a halogenated alkoxylated-benzoic acid, or a salt of an alkoxylated benzene sulfonic acid.
US Pat. No. 10,363,215

POROUS MICROPARTICLES WITH HIGH LOADING EFFICIENCIES

1. A method of making a double emulsion comprising:preparing by mechanical dispersion a first portion as a high internal phase emulsion, the first portion as the high internal phase emulsion comprising at least one biodegradable polymeric material and at least one cross-linking agent in an organic phase, and further comprising a chemical to prevent Ostwald ripening in an aqueous phase; and
adding drop wise the first portion in a second portion to form a porous microparticle-like composition, the second portion being in an aqueous phase,
wherein the aqueous phase of the first portion is encapsulated in the porous microparticle-like composition,
wherein the biodegradable polymeric material comprises:
a macromer having at least one end group selected from one or more of an acrylate and a methacrylate;
one or more linkages in the macromer, the one or more linkages selected from one or more of an anhydride and an ester,
wherein the biodegradable polymeric material has an octanol-water partition coefficient of between about 2 and about 8,
wherein the biodegradable polymeric material has a viscosity of between about 0.08 cP and about 1000 cP;
wherein the porous microparticle-like composition includes a porous region containing at least one substance selected to be one or more of compatible with a biologic system, and active in a biologic system,
wherein the porous microparticle-like composition has a spherical shape and a cross sectional diameter that is of a generally uniform size, the cross-sectional diameter in a range from between about 20 micrometers and about 1000 micrometers, with a standard deviation that is not more than 50 micrometers when the cross-sectional diameter is greater than 300 micrometers, and
wherein the first portion and the second portion are solvent free.
US Pat. No. 10,363,218

SYNTHESIS OF PROBIOTIC NANOPARTICLES

King Saud University, Ri...

1. An method of fabricating a probiotic nanoparticle, comprising:(a) dissolving a probiotic in methanol to form a first solution;
(b) spraying the first solution into boiling water at a controlled flow rate under ultrasonic conditions to form a sonicated solution; and
(c) stirring the sonicated solution to provide the probiotic nanoparticle.
US Pat. No. 10,363,733

PHOTOSENSITIVE RESIN COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND POLYMER COMPOUND

FUJIFILM CORPORATION, To...

1. A positive type lithographic printing plate precursor comprising:a recording layer which contains a photosensitive resin composition on a support having a hydrophilic surface,
wherein the photosensitive resin composition comprises:
a polymer compound which has an amine bond or a quaternary ammonium salt bond in the main chain, and at least one bond selected from the group consisting of a urea bond, a urethane bond, and a carbonate bond in the main chain and has a sulfonamide group or a phenolic hydroxyl group in the main chain and/or the side chain; and
an infrared absorbing material.
US Pat. No. 10,365,269

SYSTEM AND METHODS FOR DETECTING RIBOSOME INHIBITION

1. A method of measuring ribosome inhibition, the method comprising:providing a genetically-modified cell comprising:
an aminoglycoside-sensitive orthogonal 16S rRNA (O-16S) coding region bearing a mutated anti-Shine-Dalgarno (O-ASD) sequence;
a repressor/operator pair that comprises:
a coding region that encodes a transcriptional regulator and having an orthogonal SD (O-SD) sequence complementary to the 16S rRNA O-ASD sequence; and
an operator sequence repressable by the transcriptional regulator; and
a polynucleotide encoding a detectable reporter operably linked to the operator sequence repressable by the transcriptional regulator;
contacting the cell with a test compound; and
detecting a signal produced by the reporter, wherein intensity of the signal indicates a dose dependent degree of ribosome inhibition.
US Pat. No. 10,364,246

SMALL MOLECULE INHIBITORS OF THE JAK FAMILY OF KINASES

Janssen Pharmaceutica NV,...

1. A compound selected from the group consisting of2-(1-((1r,4r)-4-(Cyanomethyl)cyclohexyl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-N-(2-hydroxy-2-methylpropyl)acetamide;
2-((1r,4r)-4-(2-(1H-Imidazol-4-yl)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclohexyl)acetonitrile;
2-(1-((1r,4r)-4-(Cyanomethyl)cyclohexyl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-N-((1-hydroxycyclopropyl)methyl)acetamide; and
pharmaceutically acceptable salts, and combinations thereof.
US Pat. No. 10,363,223

DELAYED-RELEASE ENCAPSULATION OF DEER VELVET POWDER TO PROTECT THE DEER VELVET POWDER UNTIL MICELLIZATION AND ABSORPTION WITHIN THE TERMINAL ILLIUM

1. A capsule of deer velvet powder for ensuring delivery of unaltered molecules of the deer velvet powder systemically to organs of a body, the body having a stomach and a small intestine, the small intestine having a terminal ileum, the capsule of deer velvet powder comprising:a delayed release capsule; and
a quantity of deer velvet powder contained within the delayed release capsule,
the delayed release capsule made using hydroxypropyl methylcellulose, and
the delayed release capsule configured to resist digestive processes in the stomach so as to release the quantity of deer velvet powder substantially along the small intestine, thereby ensuring micellization and absorption of various components of the deer velvet powder along the terminal ileum.
US Pat. No. 10,363,224

EXTENDED-RELEASE TOPIRAMATE CAPSULES

UPSHER-SMITH LABORATORIES...

1. A method of dosing a subject for the treatment of convulsions, the method comprising:administering an extended-release topiramate capsule once daily to the subject, wherein the extended-release topiramate capsule comprises:
a capsule shell comprising a single population of coated particles;
wherein each coated particle comprises a core and a coating thereon;
wherein each particle core comprises a homogeneous mixture comprising topiramate throughout its core; and
wherein the coating comprises one or more release controlling agent(s);
wherein the extended-release topiramate capsule, when given as a single-dose to a healthy human subject, achieves an AUC0-inf of 170 to 210 h??g/mL within a 95% confidence interval, and a Cmax of 2 to 4 ?g/mL within a 95% confidence interval.
US Pat. No. 10,363,225

NON-BLEEDING BIOACTIVE NATURAL PIGMENTS WHICH PREVENT COLOR AND DUST EXPLOSIONS, METHOD OF PREPARATION THEREOF

1. A Non-bleeding curcumin (NBC) consisting of curcumin and a coating of polymer, whereinthe polymer is selected from the group consisting of hydroxypropyl methylcellulose, hydroxypropyl cellulose, polyvinyl alcohol and mixtures thereof;
the NBC contains concentration of curcuminoids not less than 90% (w/w) and up to 95% (w/w) measured by HPLC, which is substantially equivalent to standard curcumin with 95% purity;
the NBC having the particle size distribution in the range of 180 to 2000 microns;
the NBC retains radical scavenging property, biological activity, flavor, and color of said standard curcumin;
and the polymer prevents color leakage, bleeding, staining or dusting during industrial processing of said curcumin.
US Pat. No. 10,363,229

METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER

1. A method for treating a metastatic cancer in a subject having the metastatic cancer comprising administering to the subject a therapeutically effective amount of methyl sulfone, thereby treating the cancer, wherein the therapeutically effective amount comprises a solution of methyl sulfone in the range of 0.2 to 0.6 mg methyl sulfone/ml solvent, or 1.0 to 5.0 mg methyl sulfone/ml solvent, and wherein administration of the methyl sulfone to the subject induces cells of the cancer to revert to a normal cellular phenotype from a cancer cell phenotype.
US Pat. No. 10,364,512

MULTIFILAMENT AND BRAID

TOYOBO CO., LTD., Osaka-...

10. A braid comprising a multifilament comprising 5 or more monofilaments, whereinthe braid shows 1000 times or more in number of reciprocating abrasions at break in an abrasion resistance test measured at a load of 5 cN/dtex in accordance with JIS L-1095, and
the multifilament contains polyethylene having an intrinsic viscosity [?] of 5.0 dL/g or more and 40.0 dL/g or less and substantially including ethylene as a repeating unit.
US Pat. No. 10,365,280

COMPOSITIONS AND METHODS FOR TREATING MALIGNANCIES

DANA-FARBER CANCER INSTIT...

1. A method for identifying a therapeutic agent for treating multiple myeloma (MM), the method comprising:(a) providing a first polypeptide comprising a CD147 polypeptide and a second polypeptide comprising an extracellular cyclophilin A (eCyPA) polypeptide sequence under conditions that allow for binding of the CD147 polypeptide and the eCyPA sequence;
(b) contacting the complex with a test agent;
(c) determining whether the test agent disrupts binding of the first and second polypeptide,wherein disruption of the binding of the first polypeptide and second polypeptide by the test agent indicates the test agent is a putative therapeutic agent for treating MM;(d) contacting the putative therapeutic agent with a multiple myeloma (MM) cell population expressing CD147; and
(e) determining whether the putative therapeutic agent inhibits migration of MM cells from the MM cell population into bone marrow,
wherein inhibition of MM cell migration indicates the test agent is a therapeutic agent for treating MM.
US Pat. No. 10,365,281

BIOMARKERS OF RAPID PROGRESSION IN ADVANCED NON-SMALL CELL LUNG CANCER

Rush University Medical C...

1. A method for measuring a panel of biomarkers in a subject suspected of having rapidly progressing lung cancer the method comprising:obtaining a biological sample from the subject;
determining whether the subject is treatment naïve or has received at least one treatment;
assaying a level of each biomarker in a first biomarker panel or a second biomarker panel in the biological sample, the first biomarker panel comprising sTNFRI, sTNFRII, CA 19-9, Follistatin, Total PSA, TNF-? and IL-6 for treatment naïve subjects and the second biomarker panel comprising TRAIL, sTNFRI, IGFBP-1, sEGFR, IGF-1, TGF-?, HGF, MMP-7, MMP-2, ?-fetoprotein, Osteopontin, sVEGFR2 and IL-6 for subjects having received at least one treatment.
US Pat. No. 10,365,282

METHOD AND BIOMARKER FOR DETECTING METASTASIS OF SARCOMA

SHANGHAI KEXIN BIOTECH CO...

1. A method for diagnosing a subject suspect of having sarcoma metastasis, the method comprising:obtaining a biological sample of the subject, wherein the biological sample is serum or plasma;
detecting a level of a N-terminal segment of moesin in the biological sample;
comparing the level of the N-terminal segment of moesin detected in the biological sample of the subject to a reference level of the N-terminal segment of moesin detected from a reference sample; and
administering to the subject a treatment for metastasis of a sarcoma when the level of the N-terminal segment of moesin detected in the biological sample is higher than the reference level.
US Pat. No. 10,363,235

COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF TREATING OR PREVENTING FIBROSIS USING SAME

Afimmune Limited, (IE)

1. A method of reducing or preventing fibrosis in a subject in need thereof, the method comprising;identifying the subject as having or as having an increased risk for developing fibrosis associated with an organ or tissue selected from the group consisting of: liver, heart, mediastinum, bone marrow, retroperitoneaum, skin, intestine, joint, and a reproductive organ, or a combination thereof; and, based on the identification,
administering to the subject a composition comprising 15-HEPE wherein the 15-HEPE represents at least 80% by weight of all fatty acids in the pharmaceutical composition.
US Pat. No. 10,364,260

PROCESS FOR PREPARING TRIS[3-(ALKOXYSILYL)PROPYL] ISOCYANURATES

Evonik Degussa GmbH, Ess...

1. A process for preparing at least one tris[3-(alkoxysilyl)propyl] isocyanurate selected from the group consisting of tris[3-(trialkoxysilyl)propyl] isocyanurate, tris[3-(alkyldialkoxysilyl)propyl] isocyanurate and tris[3-(dialkylalkoxysilyl)propyl] isocyanurate by hydrosilylation, the process comprising:(A) initially charging a mixture comprising at least one H-silane selected from the group consisting of hydrotrialkoxysilane, hydroalkyldialkoxysilane, and hydrodialkylalkoxysilane, with at least one carboxylic acid and a Pt catalyst, and heating the mixture to a temperature of 50 to 140° C.,
(B) adding a mixture of 1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione and at least one alcohol to the mixture obtained in (A) while mixing,
(C) leaving the mixture obtained in (B) to react while mixing and
(D) working up the product mixture thus obtained.
US Pat. No. 10,364,262

METHOD FOR THE SYNTHESIS OF N-PHOSPHONOMETHYLIMINODIACETIC ACID

Monsanto Technology LLC, ...

1. A method for synthesis of N-phosphonomethyliminodiacetic acid or derivatives thereof selected from the group consisting of phosphonate esters of N-phosphonomethyliminodiacetic acid, carboxylate esters of N-phosphonomethyliminodiacetic acid, phosphonate and carboxylate esters of N-phosphonomethyliminodiacetic acid, N-phosphonomethyliminodiacetic acid salts, phosphonate esters of N-phosphonomethyliminodiacetic acid salts, carboxylate esters of N-phosphonomethyliminodiacetic acid salts and phosphonate-carboxylate esters of N-phosphonomethyliminodiacetic acid salts, wherein a cation of the salt is selected from the group consisting of ammonium, isopropylammonium, ethanolammonium, dimethylammonium, trimethylsulfonium, sodium and potassium,comprising the steps of:
a) forming an anhydrous reaction mixture comprising an acid catalyst, a compound of the following general formula R1—CH2—NX—CH2—R2 and a compound having one or more P—O—P anhydride moieties, to form a compound having the general formula R1—CH2—N(—CH2PO3R32)(—CH2—R2), wherein in the compound of the formula R1—CH2—NX—CH2—R2:
X is —CH2—COOH and R1 and R2 are each independently nitrile or C1-C4 alkyl carboxylate, or R1 and R2 are both carbonyl groups linked by means of a hydrogen substituted nitrogen atom or a C1-C4-alkyl substituted nitrogen atom; or
X is —CH2—OH and R1 and R2 are each independently nitrile, C1-C4 carboxylate, or carboxylic acid, or R1 and R2 are both carbonyl groups linked by means of a hydrogen substituted nitrogen atom or a C1-C4-alkyl substituted nitrogen atom;
and wherein in the compound having the general formula R1—CH2—N(—CH2PO3R32)(—CH2—R2), R3 is H, an alkyl group; and
the P—O—P anhydride moieties comprising compound is a compound wherein at least one of the one or more P—O—P anhydride moieties comprises one P atom at the oxidation state (+III) and one P atom at the oxidation state (+III) or (+V) and is selected from the group consisting of tetraphosphorus hexaoxide, P4O7, P4O8, P4O9, pyrophosphites of general formula (RO)2P—O—P(OR)2 wherein R is an alkyl or aryl group, and combinations thereof, and
b) hydrolyzing the compound having the general formula R1—CH2—N(—CH2PO3R32)(—CH2—R2) to form N-phosphonomethyliminodiacetic acid or one of its derivatives.
US Pat. No. 10,366,568

LOTTERY GAME PROVIDING A CHANCE TO WIN A JACKPOT AT A REDUCED COST TO THE PLAYER, WITH AN INCREASED REVENUE TO THE OPERATOR AND TICKET RETAILER

1. A method of playing a game of chance comprising:providing a Player an entry recorded on a printed ticket to said game of chance from a Ticket Retailer, said game of chance comprising a prize structure, said prize structure comprising a jackpot and a plurality of lesser prizes, wherein said entry provides a chance to win said jackpot and a reduced subset or no subset of said plurality of lesser prizes,
wherein said entry is printed on said ticket by a computer system configured to generate the entry based on random generation of the entry or user input and to print the entry on the printed ticket,
and wherein the entry is purchased at a reduced cost as compared to an entry with a chance to win all available prizes in the game of chance.
US Pat. No. 10,365,288

CITRULLINATED BRAIN AND NEUROLOGICAL PROTEINS AS BIOMARKERS OF BRAIN INJURY OR NEURODEGENERATION

THE JOHNS HOPKINS UNIVERS...

1. A method for detecting citrullinated brain injury biomarker proteins in a sample from a subject having or suspected of having brain injury, the method comprising:detecting in the subject's sample citrullinated arginine residues in citrullinated brain injury biomarker protein glial fibrillary acidic protein (GFAP) and/or citrullinated brain injury biomarker protein myelin basic protein (MBP) by detecting the citrullinated arginine residues in said citrullinated biomarker proteins using a detection method selected from mass spectrometry, immunoassay, electrochemical luminescent assay, electrochemical voltametry, electrochemical amperometry, atomic force microscopy, radio frequency multipolar resonance spectroscopy, confocal microscopy, non-confocal microscopy, fluorescence optical detection, luminescence optical detection, chemiluminescence optical detection, absorbance optical detection, reflectance optical detection, transmittance optical detection, birefringence optical detection, refractive index detection, surface plasmon resonance, ellipsometry, resonant mirror detection, grating coupler waveguide detection, or interferometry; thereby detecting citrullinated brain injury biomarker proteins in the subject's sample.
US Pat. No. 10,363,242

METHODS OF INHIBITING CATARACTS AND PRESBYOPIA

UNIVERSITY OF MASSACHUSET...

1. An ophthalmic composition comprisingat least one ?-crystallin charge masking agent, wherein the at least one ?-crystallin charge masking agent is a bifunctional molecule consisting of
two different end groups selected from NH2, methyl, a succinimide, a carboxylic acid, isocyanate, an isothiocyanate, a sulfonyl chloride, an aldehyde, a carbodiimide, an acyl azide, an anhydride, a fluorobenzene, a carbonate, an N-hydroxysuccinimide ester, an imidoester, an epoxide and a fluorophenyl ester,
covalently linked to a molecular bristle that is a polyethylene glycol having 4 to 200 oxyethylene groups, an alkoxy-polyethylene glycol having 4 to 200 alkoxyethylene groups, an aryloxypolyethylene glycol having 4 to 200 aryloxyethylene groups, poly(2-hydroxypropyl)methacrylamide (HPMA), poly(2-hydroxyethyl)methacrylate (HEMA), a poly(2-oxaziline), poly(m-phosphocholine, poly lysine, or poly glutamic acid, the molecular bristle having a number average molecular weight of 150 to 8000, and
an ophthalmically acceptable excipient.
US Pat. No. 10,363,244

COMPOSITIONS COMPRISING METFORMIN AND A GLUCOKINASE ACTIVATOR

vTv Therapeutics LLC, Hi...

1. A pharmaceutical composition comprising:(a) {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid or a pharmaceutically acceptable salt thereof,
(b) less than 1000 mg of metformin, and
(c) at least one pharmaceutically acceptable carrier, excipient, diluent, or a mixture thereof.
US Pat. No. 10,364,268

ION EXCHANGE MEMBRANE CHROMATOGRAPHY

Genentech, Inc., South S...

1. A method of enhancing efficiency of downstream chromatography steps for purification of antibodies consisting of:a. passing a harvested cell culture fluid composition comprising an antibody of interest and various contaminants through a cation exchange membrane, wherein the antibody and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH of about 1 to about 5 pH units below the pl of the antibody and a conductivity of ?about 40 mS/cm, which cause the membrane to bind the antibody and at least one ionic polymer contaminant, where in the ionic polymer contaminant is one or more of polyethyleneimine (PEI), polyvinylamine, polyarginine, polyvinylsulfonic acid, or polyacrylic acid;
b. overloading the cation exchange membrane to promote competitive adsorption such that at least one ionic polymer contaminant remains bound to the membrane while the antibody of interest is primarily in the effluent;
c. collecting the effluent from the cation exchange membrane comprising the antibody of interest;
d. subjecting the membrane effluent comprising the antibody of interest to a cation exchange chromatography purification step, wherein the dynamic binding capacity of the cation exchange chromatography purification step is significantly improved as a result of steps (a) through (c);
e. recovering the purified antibody from the effluent of the cation exchange chromatography purification step;
f. subjecting the cation exchange chromatography purified pool to a final polishing step; and
g. recovering the purified antibody of interest.
US Pat. No. 10,363,246

METHODS AND COMPOSITIONS FOR TREATMENT OF EPILEPTIC DISORDERS

Ovid Therapeutics Inc., ...

1. A method of treating essential tremor comprising administering to a patient in need thereof a pharmaceutical composition comprising gaboxadol or a pharmaceutically acceptable salt thereof.
US Pat. No. 10,364,271

IMMUNOTHERAPY AGAINST SEVERAL TUMORS OF THE BLOOD, IN PARTICULAR CHRONIC LYMPHOID LEUKEMIA (CLL)

Immatics Biotechnologies ...

1. A method of eliciting an immune response in a patient who has cancer, comprising administering to said patient a population of activated T cells that selectively recognize cells, which present a peptide consisting of the amino acid sequence SEQ ID NO: 63, wherein said cancer is selected from the group consisting of chronic lymphoid leukemia (CLL), acute myelogenous leukemia (AML), adrenal gland adrenal cortical adenoma, bone giant cell tumor of bone, bone non-ossifying fibroma, breast carcinoma, colon adenocarcinoma, non-Hodgkin's lymphoma, endometrium adenocarcinoma endometrioid, kidney angiomyolipoma, kidney carcinoma, kidney oncocytoma, liver focal nodular hyperplasia, liver hepatocellular carcinoma, lymph node Hodgkin's disease, lymph node papillary carcinoma of thyroid, medullary carcinoma of thyroid origin, metastatic adenocarcinoma of stomach, neurofibroma, ovary thecoma fibroma, pancreas adenocarcinoma, pancreas microcystic adenoma, parathyroid gland adenoma, rectum adenocarcinoma, skin squamous cell carcinoma, spleen chronic myeloid leukemia, stomach gastrointestinal stromal tumor (GIST), thyroid gland nodular hyperplasia, thyroid gland papillary carcinoma, and uterine cervix squamous cell carcinoma.
US Pat. No. 10,364,275

METHODS FOR TREATING INFLAMMATORY RESPONSES OR DISEASES CAUSED BY INFLAMMATION USING APOA-I BINDING PROTEIN (APOA1BP)

The Regents of the Univer...

1. A method for treating, reversing, preventing or down-regulating an inflammatory response associated with hyperlipidemia, comprising administering to an individual an effective amount of: an ApoA-I Binding Protein (APOA1BP, AIBP, or AI-BP) polypeptide or a pharmaceutical composition comprising an ApoA-I Binding Protein (APOA1BP, AIBP, or AI-BP) polypeptide,wherein the ApoA-I Binding Protein (APOA1BP, AIBP, or AI-BP) polypeptide comprises a sequence as set forth in SEQ ID NO:43, SEQ ID NO:44 or SEQ ID NO:45.
US Pat. No. 10,362,741

TOMATO FRUIT HAVING INCREASED FIRMNESS

Syngenta Participations A...

1. A Solanum lycopersicum tomato fruit with significantly increased fruit firmness at the harvesting stage comprising at least one genetic element in the cultivated Solanum lycopersicum tomato plant producing said tomato fruit, wherein said firmness is measured on the inner pericarp and is from between 1.2 to 2.0 times greater than that of fruit from a control Solanum lycopersicum tomato plant which does not have the said at least one genetic element, wherein said genetic element is identical to a genetic element of Solanum lycopersicum QTL-NIL 301 deposited with NCIMB under accession number 41662, and wherein the said genetic element of QTL-NIL 301 is linked to at least one DNA marker in the cultivated Solanum lycopersicum tomato plant, said at least one DNA marker selected from:a) NT3853, which can be detected by a forward primer of SEQ ID NO: 1 and a reverse primer of SEQ ID NO: 2;
b) NT3907, which can be detected by a forward primer of SEQ ID NO: 3 and a reverse primer of SEQ ID NO: 4;
c) TG14, which can be detected by a forward primer of SEQ ID NO: 5 and a reverse primer of SEQ ID NO: 6;
d) HOX7A, which can be detected by a forward primer of SEQ ID NO: 7 and a reverse primer of SEQ ID NO: 8;
e) CT277, which can be detected by a forward primer of SEQ ID NO: 9 and a reverse primer of SEQ ID NO: 10;
f) Lm0127, which can be detected by a forward primer of SEQ ID NO: 11 and a reverse primer of SEQ ID NO: 12;
g) Lm1650, which can be detected by a forward primer of SEQ ID NO: 13 and a reverse primer of SEQ ID NO: 14;
h) LE5100, which can be detected by a forward primer of SEQ ID NO: 15 and a reverse primer of SEQ ID NO: 16;
i) LE5200, which can be detected by a forward primer of SEQ ID NO: 17 and a reverse primer of SEQ ID NO:18;
j) HB2600, which can be detected by a forward primer of SEQ ID NO: 19 and a reverse primer of SEQ ID NO: 20; and
k) TG353, which can be detected by a forward primer of SEQ ID NO: 21 and a reverse primer of SEQ ID NO: 22.
US Pat. No. 10,363,253

COMBINATION PRODUCTS FOR THE TREATMENT OF RSV

Janssen Sciences Ireland ...

1. A combination comprising 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl-(methyl)-1-(2,2,2-trifluoroethyl)-1.3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, or a pharmaceutically acceptable salt thereof, as Compound A, and one or more Compound B selected from ribavirin, GS-5806, MDT-637, A-60444, AZ-27, CR9501, palivizumab, N-(2-fluoro-6-methylphenyl)-6-(4-(5-methyl-2-(7-oxa-2-azaspiro[3.5]nonan-2-yl)nicotinamido)-benzoyl)-5,6-dihydro-4H-benzo[b]thieno[2,3-d]azepine-2-carboxamide, and 4-amino-8-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-3H-imidazo[4,5h]isoquinoline-7,9(6H, 8H)-dione.
US Pat. No. 10,364,277

DIAGNOSIS AND TREATMENT OF AUTOIMMUNE DISEASES

NEWSOUTH INNOVATIONS PTY ...

1. A method for detecting the presence or absence of an immune cell or antibody in a subject comprising:contacting a biological sample obtained from the subject with a polypeptide, wherein the polypeptide consists of
SEQ ID NO: 2 (KRFNALQYL) or SEQ ID NO: 3 (KRFNALQCL); and
detecting the presence or absence of a binding interaction between the polypeptide and an immune cell or antibody in said sample.
US Pat. No. 10,362,742

MELON PLANTS WITH WHITEFLY RESISTANCE

NUNHEMS B.V., Nunhem (NL...

1. A non-wild, cultivated Cucumis melo plant, or part thereof, comprising resistance against whitefly, wherein said resistance is conferred by an introgression fragment on chromosome 11 in homozygous or heterozygous form and wherein said introgression fragment is from a wild plant of the species Cucumis melo, a representative sample of seeds has been deposited under accession number NCIMB 41965 and NCIMB 41966, and wherein said introgression fragment comprises at least one of the following Single Nucleotide Polymorphism (SNP) markers:a) the CC genotype or CT genotype for the SNP marker mME20364 in SEQ ID NO: 1;
b) the AA genotype or AG genotype for the SNP marker mME17490 in SEQ ID NO: 2;
c) the CC genotype or CT genotype for the SNP marker mME15248 in SEQ ID NO: 3;
d) the CC genotype or CT genotype for SNP marker mME17306 in SEQ ID NO: 4;
e) the AA genotype or AT genotype for SNP marker mME26059 in SEQ ID NO: 5;
f) the GG genotype or GA genotype for SNP marker mME38084 in SEQ ID NO: 6;
g) the CC genotype or AC genotype for SNP marker mME21974 in SEQ ID NO: 7;
h) the CC genotype or CT genotype for SNP marker mME12777 in SEQ ID NO: 8;
i) the GG genotype or GA genotype for SNP marker mME15151 in SEQ ID NO: 9;
j) the CC genotype or CA genotype for SNP marker mME26139 in SEQ ID NO: 10;
k) the CC genotype or CA genotype for SNP marker mME48762 in SEQ ID NO: 11;
l) the CC genotype or CT genotype for SNP marker mME25039 in SEQ ID NO: 12; and/or
m) the TT genotype or TC genotype for SNP marker mME40109 in SEQ ID NO: 13.
US Pat. No. 10,364,278

CHIMERIC FIBROBLAST GROWTH FACTOR 23 PROTEINS AND METHODS OF USE

New York University, New...

1. A chimeric protein comprising:an N-terminus coupled to a C-terminus, wherein the N-terminus comprises an FGF1 portion beginning at any one of residues 1 to 25 and ending at any one of residues 150 to 155 of SEQ ID NO: 1,
wherein the FGF1 amino acid positions corresponding to those selected from the group consisting of N33, K127, K128, N129, K133, R134, R137, Q142, K143, and combinations thereof are substituted to decrease binding affinity for heparin and/or heparan sulfate compared to FGF1 without substitution, and
wherein the C-terminus comprises a C-terminal portion of an FGF23 comprising amino acid residues 161-251 of SEQ ID NO: 233.
US Pat. No. 10,362,743

LETTUCE VARIETY 41-673 RZ

RIJK ZWAAN ZAADTEELT EN Z...

1. A seed of lettuce variety 41-673 RZ, a sample of seed of said variety having been deposited under NCIMB accession No. 42613.
US Pat. No. 10,364,279

PD-L1 AND PD-L2-BASED FUSION PROTEINS AND USES THEREOF

Thomas Jefferson Universi...

1. A fusion protein comprising a first domain and a second domain, wherein the first domain comprises a polypeptide that binds to and triggers PD-1 and the second domain comprises a polypeptide that binds to and triggers a TRAIL receptor, wherein the polypeptide that binds to and triggers PD-1 comprises amino acids 1-220 of SEQ ID NO: 5 and the polypeptide that binds to and triggers a TRAIL receptor comprises the amino acid sequence of SEQ ID NO: 15.
US Pat. No. 10,362,744

LETTUCE VARIETY 45-246 RZ

RIJK ZWAAN ZAADTEELT EN Z...

1. A seed of lettuce variety 45-246 RZ, a sample of seed of said variety having been deposited under NCIMB Accession No. 42636.
US Pat. No. 10,364,280

POLYPEPTIDE

AFFIBODY AB, Solna (SE)

wherein, independently from each other,X4 is selected from I, M, V and W;
X6 is selected from T and V;
X10 is selected from M and V;
X11 is selected from D and Q;
X16 is selected from N and T;
X17 is selected from A and S;
X18 is selected from G, R and W;
X20 is selected from K and R;
X25 is selected from D, N and W; and
X26 is selected from K and S;andii) an amino acid sequence which has at least 96% identity to the sequence defined in i).
US Pat. No. 10,366,841

ELECTROLYTIC CAPACITOR

Panasonic Corporation, O...

1. An electrolytic capacitor comprising:an anode body;
a dielectric layer formed on the anode body; and
a conductive polymer layer covering at least a part of the dielectric layer;
wherein:
the conductive polymer layer comprises a conductive polymer and a polymer dopant;
the polymer dopant comprises:
(A) a first unit originating from a first monomer having a polymerizable group and a sulfonate group; and
(B) a second unit originating from a second monomer having a polymerizable group and a phosphorus-containing group;
the phosphorus-containing group is represented by at least one of following general formulae:
—P(?O)(OR1)(OR2),  general formula (1):
—PH(?O)(OR3), and  general formula (2):
—PH2(?O),  general formula (3):in the general formulae (1) to (3), each of R1, R2 and R3 is independently a hydrogen atom, a hydrophilic group, a C1 to C3 alkyl group, or a cationic group, anda proportion of the second unit ranges from 5% by mole to 50% by mole both inclusive with respect to a total of the first unit and the second unit in the polymer dopant.
US Pat. No. 10,362,745

WHEAT CULTIVAR 01071782

Monsanto Technology LLC, ...

1. A plant of wheat cultivar 01071782, wherein a sample of seed of said cultivar has been deposited under ATCC Accession No. PTA-125540.
US Pat. No. 10,364,281

IMMUNOTHERAPY AGAINST MELANOMA AND OTHER CANCERS

IMMATICS BIOTECHNOLOGIES ...

1. A method for treating a patient who has cancer comprising administering to the patient a population of activated T cells that selectively recognize cancer cells that present a peptide consisting of the amino acid sequence of VLKADVVLL (SEQ ID NO: 42),wherein said cancer is selected from the group consisting of melanoma, acute myelogenous leukemia, breast cancer, bile duct cancer, brain cancer, chronic lymphocytic leukemia, colorectal carcinoma, esophageal cancer, gallbladder cancer, gastric cancer, hepatocellular cancer, non-Hodgkin lymphoma, non-small cell lung cancer, ovarian cancer, pancreatic cancer, prostate cancer, renal cell cancer, small cell lung cancer, urinary bladder cancer, and uterine cancer.
US Pat. No. 10,365,562

COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST

Rohm and Haas Electronic ...

1. A coated substrate comprising:(a) a layer of a coating composition on a substrate, the coating composition comprising a polyester resin that comprises one or more uracil moieties,
wherein the composition coating layer further comprises phenyl or anthacene groups, or where the uracil moieties are halogen-substituted; and
(b) a photoresist layer over the coating composition layer.
US Pat. No. 10,362,746

WHEAT CULTIVAR 01071514

Monsanto Technology LLC, ...

1. A plant of wheat cultivar 01071514, wherein a sample of seed of said cultivar has been deposited under ATCC Accession No. PTA-125548.
US Pat. No. 10,364,282

PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST ESOPHAGEAL CANCER AND OTHER CANCERS

IMMATICS BIOTECHNOLOGIES ...

1. A method of treating a patient who has a cancer overexpressing KRT5 polypeptide comprising the amino acid sequence of SEQ ID NO: 2, comprising administering to said patient a composition comprising a population of activated T cells that kill the cancer cells,wherein the activated T cells are cytotoxic T cells produced by contacting T cells with an antigen presenting cell that presents a peptide consisting of the amino acid sequence of SEQ ID NO: 2 in a complex with an MHC class I molecule on the surface of the antigen presenting cell in vitro, for a period of time sufficient to activate said T cell,
wherein said cancer is selected from the group consisting of esophageal cancer, lung cancer, urinary bladder cancer, head and neck cancer, and gastric cancer.
US Pat. No. 10,362,747

WHEAT CULTIVAR 01071585

Monsanto Technology LLC, ...

1. A plant of wheat cultivar 01071585, wherein a sample of seed of said cultivar has been deposited under ATCC Accession No.PTA-125547.
US Pat. No. 10,364,283

COLLAGEN HYDROLYSATE AND USE THEREOF

GELITA AG, Eberbach (DE)...

1. A collagen hydrolysate which is produced by enzymatic hydrolysis of type-B bone gelatin, wherein the collagen hydrolysate is formed from hydrolyzed collagen peptides of which at least 50% by weight have a molecular weight of 1,500 Da to 13,500 Da, and which have a weight average molecular weight in the range from 4,000 Da to 8,000 Da, wherein the bone gelatin is produced by alkaline breakdown of collagen from bones of vertebrates.
US Pat. No. 10,366,844

ELECTROCHEMICAL CELL

Seiko Instruments Inc., ...

1. An electrochemical cell comprising:an electrode body including a positive electrode body and a negative electrode body; and
an exterior body housing the electrode body, wherein
the exterior body includes:
a first container having a bottomed cylindrical shape and including a first circumferential wall section;
a second container having a bottomed cylindrical shape and including a second circumferential wall section surrounding the first circumferential wall section, the second container housing the electrode body between the second container and the first container; and
a fusing member interposed between the first circumferential wall section and the second circumferential wall section and fused to the first circumferential wall section and the second circumferential wall section, the fusing member comprising a thermally deformable layer of material different from that the first container.
US Pat. No. 10,362,750

WHEAT CULTIVAR 01071570

Monsanto Technology LLC, ...

1. A plant of wheat cultivar 01071570, wherein a sample of seed of said cultivar has been deposited under ATCC Accession No. PTA-125545.
US Pat. No. 10,364,286

MONOCLONAL ANTI-ALPHA-SYNUCLEIN ANTIBODIES FOR PREVENTING TAU AGGREGATION

1. A method for treating Alzheimer's disease without Lewy body pathology in a patient comprising:providing a monoclonal antibody, or an antigen-binding fragment thereof, that specifically binds alpha-synuclein to a patient having Alzheimer's disease without Lewy body pathology in an amount effective to inhibit aggregation of tau in the patient, wherein:
(i) the antibody, or antigen-binding fragment thereof, comprises:
a Heavy Chain CDR1 having the amino acid sequence of SEQ ID NO:1;
a Heavy Chain CDR2 having the amino acid sequence selected from SEQ ID NO:2, SEQ ID NO:33, SEQ ID NO:34, or SEQ ID NO:35;
a Heavy Chain CDR3 having the amino acid sequence of SEQ ID NO:3;
a Light Chain CDR1 having the amino acid sequence of SEQ ID NO:4;
a Light Chain CDR2 having the amino acid sequence of SEQ ID NO:5; and
a Light Chain CDR3 having the amino acid sequence of SEQ ID NO:6; or
(ii) the antibody, or antigen-binding fragment thereof, comprises:
a Heavy Chain CDR1 having the amino acid sequence of SEQ ID NO:20;
a Heavy Chain CDR2 having the amino acid sequence of SEQ ID NO:21;
a Heavy Chain CDR3 having the amino acid sequence of SEQ ID NO:22;
a Light Chain CDR1 having the amino acid sequence of SEQ ID NO:23;
a Light Chain CDR2 having the amino acid sequence of SEQ ID NO:24; and
a Light Chain CDR3 having the amino acid sequence of SEQ ID NO:25.
US Pat. No. 10,362,754

PLANTS AND SEEDS OF HYBRID CORN VARIETY CH267399

Monsanto Technology LLC, ...

1. A seed of hybrid corn variety CH267399, produced by crossing a first plant of variety CV602186 with a second plant of variety CV132428, wherein representative seeds of said varieties CV602186 and CV132428 are deposited under ATCC Accession Nos. PTA-125251 and PTA-121108, respectively.
US Pat. No. 10,364,290

ANTI-HER3/HER4 ANTIBODIES BINDING TO THE BETA-HAIRPIN OF HER3 AND THE BETA-HAIRPIN OF HER4

Hoffmann-La Roche Inc., ...

1. An isolated nucleic acid encoding an antibody that binds to human HER3 and binds to human HER4, wherein the antibody comprises:(a) HVR-H1 comprising the amino acid sequence of SEQ ID NO:25,
(b) HVR-H2 comprising the amino acid sequence of SEQ ID NO:26,
(c) HVR-H3 comprising the amino acid sequence of SEQ ID NO:27,
(d) HVR-L1 comprising the amino acid sequence of SEQ ID NO:28,
(e) HVR-L2 comprising the amino acid sequence of SEQ ID NO:29, and
(f) HVR-L3 comprising the amino acid sequence of SEQ ID NO:30.
US Pat. No. 10,362,755

PLANTS AND SEEDS OF HYBRID CORN VARIETY CH475588

Monsanto Technology LLC, ...

1. A seed of hybrid corn variety CH475588, produced by crossing a first plant of variety CV181138 with a second plant of variety CV759867, wherein representative seeds of said varieties CV181138 and CV759867 are deposited under ATCC Accession Nos. PTA-123825 and PTA-124497, respectively.
US Pat. No. 10,363,267

DIARRHEA-PREVENTING NUTRITIONAL COMPOSITION

OTSUKA PHARMACEUTICAL FAC...

1. A nutritional composition for preventing diarrhea comprisinga pectin having a degree of esterification of 10 to 30%, a degree of amidation of 0 to 25%, and a degree of free acids of 64% or more and less than 85%,
lipid,
carbohydrate other than the pectin, and
protein,
wherein the pectin has a weight-average molecular weight of 350000 to 600000.
US Pat. No. 10,362,756

PLANTS AND SEEDS OF HYBRID CORN VARIETY CH482861

Monsanto Technology LLC, ...

1. A seed of hybrid corn variety CH482861, produced by crossing a first plant of variety CV181138 with a second plant of variety CV093813, wherein representative seeds of said varieties CV181138 and CV093813 are deposited under ATCC Accession Nos. PTA-123825 and PTA-123818, respectively.
US Pat. No. 10,364,292

MONOVALENT BLOOD BRAIN BARRIER SHUTTLE MODULES

Hoffmann-La Roche Inc., ...

1. A blood brain barrier shuttle module comprising a brain effector entity, optionally a linker and exactly one (monovalent) binding entity which binds to transferrin receptor (TfR), wherein the linker if present couples the effector entity to the monovalent binding entity, wherein the monovalent binding entity comprises an anti-TfR antibody or fragment thereof comprising (a) a HVR-H1 comprising the amino acid sequence of SEQ ID NO: 109; (b) a HVR-H2 comprising the amino acid sequence of SEQ ID NO: 110; (c) a HVR-H3 comprising the amino acid sequence of SEQ ID NO: 112; (d) a HVR-L1 comprising the amino acid sequence of SEQ ID NO: 113; (e) a HVR-L2 comprising the amino acid sequence of SEQ ID NO: 114; and (f) a HVR-L3 comprising the amino acid sequence of SEQ ID NO: 115.
US Pat. No. 10,364,293

POLYPEPTIDE BINDING TO EXTRACELLULAR DOMAIN OF EPIDERMAL GROWTH FACTOR RECEPTOR

KOREA ADVANCED INSTITUTE ...

1. A polypeptide which has the ability to bind specifically to epidermal growth factor receptor protein and comprises the amino acid sequence of any one of SEQ ID NOS: 6 to 8.
US Pat. No. 10,363,270

METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL IMMUNOTHERAPY

CELLECTIS, Paris (FR)

1. A method for treating a cancer patient using immunotherapy comprising:providing primary human T cells from a single donor;
co-electroporating into said primary human T-cells:
(a) RNAs encoding two half TALE-nucleases having Fok-I catalytic domains, wherein the two half TALE-nucleases dimerize and recognize two half-targets separated by a spacer of 11-15 bp and cleave the target sequence of SEQ ID NO:40 within a gene encoding CD52, and
(b) RNAs encoding two half TALE-nucleases having Fok-I catalytic domains,
wherein the two half TALE-nucleases dimerize and recognize two half-targets separated by a spacer of 11-15 bp and cleave the target sequence of SEQ ID NO:37 within a gene encoding TCR?,
to generate doubly-inactivated human T-cells having both the CD52 and the TCR? genes inactivated;
modifying the doubly inactivated human T-cells to express a chimeric antigen receptor; and
infusing at least 104 of the doubly inactivated human T-cells expressing a chimeric antigen receptor into said cancer patient for immunotherapy treatment.
US Pat. No. 10,364,300

METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW

Bridgestone Corporation, ...

1. A method for preparing a coupled polymer, the method comprising the steps of:(i) polymerizing conjugated diene monomer to form a reactive polymer, where said step of polymerizing employs either a coordination catalyst or an anionic initiator, and
(ii) reacting the reactive polymer with a carboxylic or thiocarboxylic ester containing a nitro group, where the carboxylic or thiocarboxylic ester containing a nitro group includes a single nitro group.
US Pat. No. 10,365,070

BALLISTIC RESISTANT ARTICLE WITH NON-UNIFORMLY DISTRIBUTED MATRIX MATERIAL AND METHOD TO MANUFACTURE SAID ARTICLE

TEIJIN ARAMID B.V., Arnh...

1. A ballistic resistant article comprising at least one consolidated composite,wherein the at least one consolidated composite comprises a layer A and a layer B bonded to one another, each layer A and each layer B having
a first surface,
a second surface opposite to the first surface, and
a cross-section extending from the first surface to the second surface,
and each layer A and each layer B comprises a network of fibers having a strength of at least 800 mN/tex (1100 MPa) according to ASTM D 7269-07, and the fibers in each layer A and each layer B are impregnated with a matrix material,
wherein the matrix material is distributed along the cross-section of each layer in a concentration gradient in which the concentration starts with a maximum value on the first surface, so that the first surface is rich in matrix material, decreases along the cross-section and reaches a minimum value on the second surface, so that the second surface is poor in matrix material, and the matrix material comprises a mixture of 75 to 95 wt. % of a polychloroprene, and 5 to 25 wt. % of a random copolymer of vinyl chloride and an acrylic ester, based on a weight of the mixture.
US Pat. No. 10,362,770

TRANSGENIC ANIMAL FOR PRODUCTION OF ANTIBODIES HAVING MINIMAL CDRS

Crystal Bioscience Inc., ...

1. A transgenic chicken that comprises a genome comprising a recombinant immunoglobulin heavy chain (IgH) locus comprising:(a) a functional IgH gene comprising a nucleic acid encoding a heavy chain variable region comprising:
(i) heavy chain complementarity determining (CDR) regions; and
(ii) a heavy chain framework; and,
(b) a plurality of pseudogenes that encode heavy chain variable regions each comprising:
(i) heavy chain CDR regions; and
(ii) a heavy chain framework region that is identical in amino acid sequence to the heavy chain framework of a) (ii);
wherein said nucleic acid of (a) and pseudogene of (b), are exogenous to the genome of said transgenic chicken,
wherein said plurality of pseudogenes are operably linked to said functional IgH gene and donate nucleotide sequences to the nucleic acid of (a) by gene conversion in said transgenic chicken; and
wherein said transgenic chicken expresses a polyclonal antiserum comprising a diversified IgH variable region.
US Pat. No. 10,363,282

ANALOGS OF C5A AND METHODS OF USING SAME

Board of Regents of The U...

1. A method of activating an immune cell at a site of infection or disease comprising administering an effective amount of an oligopeptide C-terminal analog of C5a to a mammal, wherein said immune cell is an antigen presenting cell, said analog not attached to an antigen, and said analog having response-selective C5a receptor binding activity, wherein the analog is SEQ ID NO: 4.
US Pat. No. 10,362,771

METHOD FOR KNOCK-IN OF DNA INTO TARGET REGION OF MAMMALIAN GENOME, AND CELL

KYOTO UNIVERSITY, Kyoto ...

1. A method for knock-in of a donor DNA into the genome of a cell, comprising introducing at least one artificial nuclease system G capable of cleaving one or two target sequences G of the cell genome, the donor DNA, and two single-stranded oligonucleotides (ssODNs) into the cell,the artificial nuclease system G cleaving the one or two target sequences G on the cell genome to generate two DNA double-strand break (DSB) sites on the cell genome,
the two ssODNs being Up-ssODN complementary to DSB site g1, one of the DSB sites generated by the target sequence G cleavage of the cell genome, and to upstream introduction site D1 of the donor DNA, and Down-ssODN complementary to DSB site g2, the other DSB site of the cell genome, and to downstream introduction site D2 of the donor DNA, and
the donor DNA being knocked-in between the two DSB sites g1 and g2 in the one or two target sequences G of the cell genome using the two ssODNs (Up-ssODN and Down-ssODN),
wherein the donor DNA is a plasmid comprising one or two target sequences, the artificial nuclease system comprises artificial nuclease system G comprising Cas9 nuclease and one or two guide RNAs-G (gRNAs-G) corresponding to the one or two target sequences G of the cell genome, and artificial nuclease system D comprising Cas9 nuclease and one or two guide RNAs-D (gRNAs-D) corresponding to the one or two target sequences D of the donor DNA, the one or two target sequences G of the cell genome are cleaved by the artificial nuclease system G to generate DSB sites g1 and g2 on the cell genome, and the one or two target sequences D on the donor DNA plasmid are cleaved by the artificial nuclease system D to generate upstream introduction site D1 and downstream introduction site D2 of the plasmid-derived donor DNA to be knocked-in into the genome.
US Pat. No. 10,363,541

SYSTEMS AND METHODS FOR INTERIOR ENERGY-ACTIVATION FROM AN EXTERIOR SOURCE

IMMUNOLIGHT, LLC., Detro...

1. A method for modifying a hydrophobic polymer surface, comprising:disposing in contact with the hydrophobic polymer surface a liquid composition comprising monomeric precursors to a hydrophilic polymer and one or more energy modulation agents, wherein the one or more energy modulation agents are resistant to chemical interaction with the liquid composition and hydrophobic polymer surface; and
applying energy from at least one of x-rays, gamma rays, or an electron beam into the liquid composition, wherein the applied energy interacts with the one or more energy modulation agents and internally generates light inside the liquid composition, thereby causing the monomeric precursors to polymerize and react with the hydrophobic polymer surface, thereby grafting the hydrophilic polymer onto the hydrophobic polymer surface.
US Pat. No. 10,363,286

PEPTIDE INHIBITION OF CCR3-MEDIATED DISEASES OR CONDITIONS

The Board of Trustees of ...

1. A C—C chemokine receptor (CCR3) peptide analog comprising the amino acid sequence LLNLAISDLLFLVTLPFWIHY (SEQ ID NO:17) or LLFLVTLPFWIHYVRGHNWVFGH (SEQ ID NO:18), wherein said peptide analog is PEGylated and is up to 50 amino acid residues in length.
US Pat. No. 10,363,547

METHODS FOR MAKING CATALYST SYSTEMS

Saudi Arabian Oil Company...

1. A method for making a catalyst system, the method comprising:introducing one or more alkali or alkaline earth metals to a zincosilicate support material; and
introducing one or more platinum group metals to the zincosilicate support material; and
wherein the zincosilicate support material comprises an MFI framework type structure incorporating at least silicon and zinc.
US Pat. No. 10,363,549

CHROMIUM OXYFLUORIDE CATALYSTS HAVING HIGH FLUORINATION ACTIVITY

Arkema Inc., King of Pru...

1. A chromium oxyfluoride catalyst active for fluorination of a chlorinated compound, wherein the chromium oxyfluoride catalyst is comprised of a first chromium species and a second chromium species, wherein the first chromium species exhibits a first X-ray photoelectron spectroscopy (XPS) chromium Cr 2p3/2 peak between 576.9 eV+/?0.2 eV and 578.0 eV+/?0.2 eV and the second chromium species exhibits a second X-ray photoelectron spectroscopy (XPS) chromium Cr 2p3/2 peak between 580.0 eV+/?0.2 eV and 581.4 eV+/?0.2 eV and wherein the intensity of the second XPS chromium peak is greater than the intensity of the first XPS chromium peak.
US Pat. No. 10,362,786

STABLE AQUEOUS SPORE-CONTAINING FORMULATION

Bayer Intellectual Proper...

1. An agriculturally acceptable stable aqueous formula comprising(a) a Bacillus firmus I-1582 spores in an amount of 10% w/w to 55% w/w,
(b) glycerin in an amount of 5% w/w to 50% w/w,
(c) water,
(d) a stabilizer in an amount of 0.5% w/w to 20% w/w, comprising a chemical salt selected from the group consisting of sodium sulfate, sodium chloride, potassium chloride and zinc sulfate; and
(e) clothianidin.
US Pat. No. 10,362,787

METHOD FOR PROPAGATING MICROORGANISMS WITHIN PLANT BIOREACTORS AND STABLY STORING MICROORGANISMS WITHIN AGRICULTURAL SEEDS

AIT AUSTRIAN INSTITUTE OF...

1. A method of producing a indol-3 carboxylic acid within a bacterial colonized cereal plant bioreactor, the method comprising:a. germinating a cereal seed into which at least one inoculant bacterial endophyte has been introduced, wherein the bacterial endophyte is from the genus Burkholderia, comprises a 16S rRNA nucleic acid sequence comprising SEQ ID NO: 1446 and can grow on nitrogen free media, to produce the bacterial colonized cereal plant bioreactor; and
b. growing the bacterial colonized cereal plant bioreactor under conditions such that the bacterial endophyte proliferates and the indol-3 carboxylic acid is produced in the bacterial colonized cereal plant bioreactor, wherein the indol-3 carboxylic acid is produced at a higher concentration in the bacterial colonized cereal plant bioreactor compared to an isoline plant grown from a non-inoculated cereal seed.

US Pat. No. 10,368,291

CONTROLLING USE OF VEHICULAR WI-FI HOTSPOTS BY A HANDHELD WIRELESS DEVICE

GM Global Technology Oper...

1. A method of controlling use of vehicular Wi-Fi hotspots by a handheld wireless device, comprising the steps of:(a) detecting that the handheld wireless device is communicating via a Wi-Fi hotspot;
(b) determining at the handheld wireless device that the Wi-Fi hotspot is provided by a vehicle, including:
(b1) comparing a received identifier of the Wi-Fi hotspot with content of a database containing vehicular Wi-Fi identifiers; and
(b2) identifying the received identifier in the database containing vehicular Wi-Fi identifiers; and
(c) enabling one or more default prohibitions against transmitting low-priority data from the handheld wireless device to a remote server via the Wi-Fi hotspot provided by the vehicle and a cellular wireless carrier system to which the vehicle is connected while the handheld wireless device communicates with the Wi-Fi hotspot provided by the vehicle.

US Pat. No. 10,368,288

SYSTEMS AND METHODS FOR CONNECTING DEVICES THROUGH INTERMEDIATE NODES

Bridgefy, Inc., San Fran...

1. A method for wireless communications, comprising:receiving, at an apparatus, a request to forward a first packet previously received at the apparatus, the first packet includes a first identifier of a first recipient device of the first packet;
determining, based on the first identifier, whether the first recipient device is in a list of wireless devices within a wireless range of the apparatus;
including, based on the determination, the first packet into an outgoing queue comprising a list of packets to be forwarded;
establishing one or more connections with one or more wireless devices in the list of wireless devices;
upon including the first packet into the outgoing queue, decrementing a value in the first packet indicating a remaining number of times the first packet is allowed to be transferred from one wireless device to another wireless device;
forwarding, in accordance with the decremented value, the first packet from the outgoing queue to the one or more wireless devices via the established one or more connections;
receiving, at the apparatus, a second packet having a second identifier of a second recipient device;
determining, based on the second identifier, that the second recipient device is the same as the apparatus; and
transmitting a reach packet directly to the one or more wireless devices from the list of wireless devices to stop forwarding the second packet.

US Pat. No. 10,368,287

METHOD AND APPARATUS FOR RESELECTING CELL IN WIRELESS COMMUNICATION SYSTEM

LG ELECTRONICS INC., Seo...

1. A method for allocating an uplink (UL) resource in a wireless communication system supporting a low latency service, the method performed by a user equipment (UE) and comprising:receiving a first control message including first scheduling delay information indicating a delay time related to resource allocation of a serving base station from the serving base station;
transmitting a request message including a UL resource request information element (IE) for requesting UL resource allocation to the serving base station or a neighboring base station based on the first control message; and
receiving a response message in response to the request message from the serving base station or the neighboring base station,
wherein the UL resource is allocated to the UE by the serving base station or the neighboring base station based on the request message, and
wherein the UL resource request IE includes a UL grant offset field indicating a UL resource request time of the UE.

US Pat. No. 10,368,285

STATION (STA), ACCESS POINT (AP) AND METHOD OF COMMUNICATION IN THE PRESENCE OF SPATIAL REUSE

Intel IP Corporation, Sa...

1. An apparatus of a first station (STA), the apparatus comprising: memory; andprocessing circuitry, configured to:
determine a received signal strength indicator (RSSI) based on one or more inbound physical layer convergence procedure (PLCP) protocol data units (PPDUs) received at the first STA in a channel;
contend for a transmission opportunity (TXOP) to obtain access to the channel;
determine, based at least partly on a comparison between the RSSI of the one or more inbound PPDUs received at the first STA and a predetermined threshold, whether spatial reuse (SR) transmissions by one or more second STAs are permissible, the SR transmissions by the one or more second STAs at least partially concurrent to transmissions by the first STA within the TXOP in the channel; and
encode, for transmission in the channel during the TXOP, an outbound PPDU that includes an SR indicator that is based on the comparison, wherein a first value of the SR indicator indicates that the SR transmissions by the one or more second STAs at least partially concurrent with transmission of the outbound PPDU by the first STA are permissible and a second value of the SR indicator indicates that the SR transmissions by the one or more second STAs at least partially concurrent with transmission of the outbound PPDU by the first STA are impermissible.

US Pat. No. 10,368,283

CONVERGENCE OF CLOUD AND MOBILE ENVIRONMENTS

International Business Ma...

1. A method comprising:receiving, by one or more processors, a request to complete a computing task on a first device, wherein:
the first device comprises at least a portion of a cloud computing environment,
the request to complete the computing task originates from a second device, and
the computing task requires a physical sensor;
identifying, by one or more processors, one or more capabilities of the first device, wherein a first capability of the one or more capabilities is identified based, at least in part, on whether the first device has the physical sensor;
determining, by one or more processors, that the computing task should be offloaded from the first device to a third device based, at least in part, on the first device lacking the physical sensor and the third device having the physical sensor;
offloading, by one or more processors, the computing task from the first device to the third device;
receiving, by one or more processors, a result of the computing task from the third device; and
sending, by one or more processors, the result of the computing task from the first device to the second device.

US Pat. No. 10,368,281

TELEPHONE WITH AUTOMATIC SWITCHING BETWEEN CELLULAR AND VOIP NETWORKS

Vasu Networks Corporation...

1. A device comprising:a switching system to switch operation between a first communication module and a second communication module, wherein during an established communication if a context changes, the established communication is switched to a second communication over a second network, wherein switching is based on detecting a second context being preferred over the context within a set of networks, wherein upon activation of a timer, the switching system causes the second communication module to change state from a sleep mode to an active mode, wherein the timer is activated to establish a time window of a predefined size, wherein if a Wi-Fi signal monitor detects that a Wi-Fi signal level is below a second predefined threshold value Vth2, the timer is activated to establish a second time window of a second predefined size T2, wherein a third predefined threshold value Vth3 is smaller than Vth2.

US Pat. No. 10,368,279

COMMUNICATION METHOD, RADIO TERMINAL, AND BASE STATION

KYOCERA Corporation, Kyo...

1. A communication method comprising:transmitting first information for causing a radio terminal to hold context information of the radio terminal, from a network to the radio terminal in a radio resource control (RRC) connected state, wherein the context information includes a cell-radio network temporary identifier (C-RNTI) allocated to the radio terminal; and
in the radio terminal:
holding the context information without discarding the context information, based on the first information, even if the radio terminal transitions from the RRC connected state;
performing a cell reselection after transitioning from the RRC connected state;
receiving, from a reselected cell, information for determining whether the context information is available in the reselected cell; and
only when the context information is available in the reselected cell, performing control to transmit, to the reselected cell, information for promoting use of the context information, wherein
the radio terminal includes, into message 3 in a random access procedure, predetermined information for promoting the use of the context information, and
the message 3 is transmitted from the radio terminal to the reselected cell.

US Pat. No. 10,368,273

METHOD AND SYSTEM FOR SUPPORTING FAST RECOVERY OF USER EQUIPMENT

Samsung Electronics Co., ...

1. A method by a first base station in a wireless communication system, the method comprising:receiving a radio link failure (RLF) indication message related to an RLF of a terminal from a second base station;
identifying whether to trigger a handover preparation procedure based on information included in the RLF indication message; and
transmitting a handover request message to the second base station based on the handover preparation procedure being triggered,
wherein the handover preparation procedure is triggered based on the RLF indication message not including an indicator related to a radio resource control (RRC) connection setup and based on terminal context included in the RLF indication message matching context found by the first base station, and
wherein the handover preparation procedure is not triggered based on the RLF indication message including the indicator related to the RRC connection setup.

US Pat. No. 10,368,272

METHOD AND APPARATUS FOR TRANSMITTING INDICATION IN WIRELESS COMMUNICATION SYSTEM

LG ELECTRONICS INC., Seo...

1. A method for transmitting, by a first eNodeB (eNB), a transport network layer (TNL) address in a wireless communication system, the method comprising:receiving, by the first eNB, a first configuration transfer message,
wherein the first configuration transfer message includes information on an indirect X2 interface between the first eNB and a second eNB,
wherein the indirect X2 interface goes through an X2 gateway (X2-GW) between the first eNB and the second eNB,
wherein the X2-GW is not connected to a mobility management entity (MME), and
wherein the information on the indirect X2 interface is generated by the second eNB; and
transmitting, by the first eNB, a second configuration transfer message towards the second eNB,
wherein the second configuration transfer message includes a TNL address of the X2-GW based on the information on the indirect X2 interface.

US Pat. No. 10,368,271

METHOD AND APPARATUS FOR TRANSMITTING SYNCHRONIZATION SIGNALS FOR A MOVING CELL

LG ELECTRONICS INC., Seo...

1. A method for a moving cell base station to transmit a moving cell synchronization signal sequence, the method comprising:mapping the moving cell synchronization signal sequence to a first frequency region; and
transmitting the moving cell synchronization signal sequence via the first frequency region,
wherein the first resource region is different from a second frequency region, and
wherein the second frequency region is for transmitting a synchronization signal for a user equipment which cannot support the moving cell base station.

US Pat. No. 10,368,268

METHODS, SYSTEMS AND DEVICES FOR SUPPORTING LOCAL BREAKOUT IN SMALL CELL ARCHITECTURE

Samsung Electronics Co., ...

1. A method by a mobility management entity (MME), the method comprising:receiving, from a first base station, an initial user equipment (UE) message including a local home network (LHN) identification (ID) of the first base station;
determining whether to establish a local breakout bearer based on subscription information of a UE and the LHN ID; and
transmitting, to the first base station, based on determining to establish the local breakout bearer, an initial context setup request message including information associated with the local breakout bearer,
wherein a second base station addition request message is transmitted to a second base station having a same LHN ID as the LHN ID of the first base station for dual connectivity.

US Pat. No. 10,368,260

METHOD AND UE FOR MEASURING CSI-RS

Samsung Electronics Co., ...

1. A method to measure a channel state indication (CSI)-reference signal (RS) in a user equipment (UE), the method comprising:receiving a signal including configuration information and combination information, the combination information indicating a combination of at least two CSI-RS resources selected from among a plurality of CSI-RS resources;
obtaining a resource location based on the combination information and the configuration information; and
measuring the CSI-RS based on the resource location,
wherein the at least two CSI-RS resources indicated by the combination information are located adjacent to each other on a frequency domain, and
wherein the plurality of CSI-RS resources are represented as symbols 5 to 6 of subcarriers 2 to 4 and 7 to 9, symbols 9 to 10 of all subcarriers, and symbols 12 to 13 of subcarriers 2 to 4 and 7 to 9 , if an antenna port number is larger than 2, and the plurality of CSI-RS resources are represented as symbols 5 to 6 of subcarriers 2 to 5 and 7 to 10, symbols 9 to 10 of all subcarriers, and symbols 12 to 13 of subcarriers 2 to 5 and 7 to 10, if the antenna port number is smaller or equal to 2.

US Pat. No. 10,368,259

METHOD FOR DETERMINING SENSOR NETWORK DELAY TIME

King Fahd University of P...

1. A method of operating a computer system to determine the performance of a wireless sensor network including a plurality of sensors, the method comprising:selecting, a sensor distribution pattern for a geographical region where the sensors are to be deployed; determining a location for a base station in the geographical region;
generating by circuitry, a plurality of sensor clusters, each sensor cluster of the plurality of sensor clusters being formed by one of a first grouping mechanism and a second grouping mechanism, the first grouping mechanism forming the sensor cluster based on a strength of a signal transmitted by each sensor, that is received by the base station, and the second grouping mechanism forming the sensor cluster based on a location of the sensor and an energy level of the sensor;
allocating, for each sensor included in the generated sensor cluster, a time-slot within a time-frame corresponding to the sensor cluster, the time-slot being utilized for transmitting a data packet from the sensor to the base station; and
evaluating by the circuitry, the performance of the first grouping mechanism and the second grouping mechanism for the selected sensor distribution pattern and base station location, by computing at least a ratio of delivered data packets to the base station to a total energy consumption, and a first delay and a second delay incurred by each data packet, wherein the first delay is an average intra-cluster delay of from 0.2 to 1 second and the second delay is an average inter-cluster delay of less than 20 seconds,
wherein the selected sensor distribution pattern is a grid pattern wherein the sensors are disposed in a manner such that a distance between adjacent sensors is a predetermined distance, in a normal distribution pattern a principle number of sensors are disposed in the center of the geographical region, and in a exponential distribution pattern, a principle number of sensors are disposed in the corner of the geographical region.

US Pat. No. 10,368,255

METHODS AND APPARATUS FOR CLIENT-BASED DYNAMIC CONTROL OF CONNECTIONS TO CO-EXISTING RADIO ACCESS NETWORKS

Time Warner Cable Enterpr...

1. A method for enhancing wireless connectivity for a mobile client device, the method comprising:receiving data from a first radio frequency (RF) receiver apparatus of the mobile client device;
evaluating, using a computerized process operative to run on the mobile client device, at least a portion of the received data to determine the presence of a first type of wireless signal; and
modifying, based on the determination of the presence of the first type of wireless signal, an energy detection (ED) threshold associated with a wireless interface of the mobile device, the wireless interface utilizing a second type of wireless signal, the modifying based at least in part on the data from the first RF receiver apparatus and configured to cause the mobile client device to preferentially utilize the wireless interface and the second type of wireless signal for data communications over the first type of wireless signal.

US Pat. No. 10,368,253

SYSTEM AND METHOD FOR MANAGING DUAL CONNECTIVITY WITH DYNAMIC ANCHOR CELL SELECTION

1. A system, comprising:a processing system including a processor; and
a memory that stores executable instructions that, when executed by the processing system, facilitate performance of operations, the operations comprising:
determining a plurality of dual connectivity ratings for a plurality of neighbor cells of a serving cell of a mobile cellular network, wherein the plurality of dual connectivity ratings are determined via a plurality of configuration update messages received from the plurality of neighbor cells;
identifying a dual connectivity capability of a mobile communication device that engages in wireless communications coordinated by the serving cell;
identifying a target cell of the plurality of neighbor cells based on a dual connectivity rating of the plurality of dual connectivity ratings; and
facilitating initiation of a dual connectivity service via the target cell based on the dual connectivity capability of the mobile communication device, wherein the target cell serves as a master cell of the dual connectivity service, and wherein the dual connectivity service comprises exchanging user plane messages between the mobile communication device, the master cell and a secondary cell of the mobile cellular network.

US Pat. No. 10,368,250

APPARATUS AND METHODS FOR COMMUNICATING WITH ULTRA-WIDEBAND ELECTROMAGNETIC WAVES

1. A method, comprising:generating, by a first waveguide system, a first plurality of electromagnetic waves according to a first communication signal, wherein the first plurality of electromagnetic waves conveys the first communication signal; and
guiding, by the first waveguide system, the first plurality of electromagnetic waves along a first span of a transmission medium, wherein the first span is supported by a first supporting device and a second supporting device, wherein the first waveguide system and a second waveguide system are coupled to the first span, wherein the first plurality of electromagnetic waves is directed to the second waveguide system, and wherein the first plurality of electromagnetic waves propagates along the first span of the transmission medium without requiring an electrical return path and without traversing the first supporting device or the second supporting device.

US Pat. No. 10,368,246

METHODS AND SYSTEMS FOR SPECTRUM MANAGEMENT

The Research Foundation f...

1. A method for determining whether to grant a request for spectrum access, comprising:electronically receiving the request for spectrum access, wherein the request comprises a desired frequency band; a desired time period, a requested transmit power, and a requested transmitter location;
determining a geographical region based on the requested transmitter location and requested transmit power;
dividing the geographical region into a set of unit-spectrum-spaces, each unit-spectrum-space comprising a unit-region of space having a sample point, a time quanta, and a frequency band;
receiving, from an RF sensor network, current spectrum consumption information for transmitters and receivers in the geographical region;
quantifying utilized-spectrum for the geographical region by:
calculating the power received from each transmitter in the geographical region at each of a plurality of sample points, wherein each sample point of the plurality of sample points corresponds to a unit-region of the geographical region;
calculating a spectrum-occupancy for each sample point by aggregating the power received from each transmitter at the respective sample point and the average ambient noise power at the respective sample point;
calculating a spectrum-occupancy for each unit-spectrum-space within the geographical region; and
aggregating the spectrum-occupancy of each unit-spectrum-space
quantifying available-spectrum for the geographical region; and
granting or denying the request for spectrum access according to the utilized-spectrum and available-spectrum.

US Pat. No. 10,368,244

PROJECTION VIA A DEVICE

MICROSOFT TECHNOLOGY LICE...

1. A system comprising:one or more processors; and
one or more computer-readable media storing processor-executable instructions that, responsive to execution by the one or more processors, cause the system to perform operations including:
determining based on a current device context that a first device is permitted to broadcast its availability to receive projected content from another device;
causing discovery data that indicates that the first device is available to receive projected content to be transmitted wirelessly;
detecting a request from a second device to project a visual representation of an execution environment generated at the second device to the first device;
ascertaining whether the second device has permission to project to the first device; and
allowing or denying the second device to project the visual representation to the first device based on whether the second device is indicated as having permission to project to the first device.

US Pat. No. 10,368,242

SYSTEM AND METHOD FOR UNIFIED AUTHENTICATION IN COMMUNICATION NETWORKS

1. A method comprising:sending, by a processing system including a processor of a mobile communication device, a first authentication request to a first communication network, wherein the mobile communication device is authenticated to the first communication network based on a credential accessible to a network element of the first communication network;
sending, by the processing system, information regarding a location of the mobile communication device to the first communication network, wherein the first communication network updates the location of the mobile communication device based on the information and determines a predicted path upon which the mobile communication device is predicted to travel;
receiving, by the processing system, a signal via the first communication network that a second communication network is available in the predicted path of the mobile communication device, wherein the network element transmits the credential to the second communication network based on the predicted path;
accessing, by the processing system, the second communication network, wherein the credential is stored prior to the accessing;
sending, by the processing system, a second authentication request to the second communication network; and
receiving, by the processing system, via the second communication network, an acknowledgement of authentication to the second communication network based on the transmitted credential.

US Pat. No. 10,368,240

PROFILE DOWNLOAD METHOD AND APPARATUS FOR USE IN WIRELESS COMMUNICATION SYSTEM

Samsung Electronics Co., ...

1. A communication method of a terminal, the method comprising:transmitting, to a profile provision server, an initial authentication message including a first challenge value for authentication of the profile provision server;
receiving, from the profile provision server, an initial authentication response message including a first data and a first signature value, wherein the first data includes the first challenge value and a second challenge value for authentication of the terminal, and the first signature value is computed over the first data;
verifying the first signature value;
generating a second data including the second challenge value and profile mapping information, and computing a second signature value over the second data;
transmitting, to the profile provision server, an authentication client a first message including the second data and the second signature value;
receiving, from the profile provision server, an authentication client response message including unencrypted information related to a profile and information indicating whether a confirmation code is required for the profile;
receiving, via a user interface, a confirmation code based on the unencrypted information related to the profile in case that the information indicates the confirmation code is required;
transmitting, to the profile provision server, a profile download request message including the confirmation code; and
receiving, from the profile provision server, a profile download response message including an encrypted profile data in response to the profile download request message.

US Pat. No. 10,368,237

TERMINAL, PROCESSING APPARATUS, PROCESSING SYSTEM, AND NON-TRANSITORY COMPUTER READABLE MEDIUM

FUJI XEROX CO., LTD., To...

1. A terminal comprising:a memory, and
a processor configured to execute:
a connection unit configured to connect the terminal to a processing apparatus via a first the for wireless communication, using connection information;
an acquisition unit configured:
to acquire identification information of the processing apparatus, and
to store the connection information for the first communication channel and the identification information in the memory, such that the connection information for the first communication channel is associated with the identification information;
a detector configured to detect, in response to there being no connection via the first communication channel from the processing apparatus for more than a predetermined period of time, that the connection between the terminal and the processing apparatus, via the first communication channel, is cut off; and
a transmitting unit configured to transmit, in response to the detector detecting that the connection via the first communication channel to the processing apparatus is cut off, the connection information from the terminal to the processing apparatus via a second communication channel,
wherein the connection information is associated with the identification information stored in the memory,
wherein the connection unit includes key information indicating a key used to communicate encrypted information via the first communication channel, and a pass phrase used to generate the key,
wherein the detector is further configured to determine whether there is no connection via the first communication channel from the processing apparatus for more than the predetermined period of time by monitoring a request to the processing apparatus for a time-out, and
wherein the processor is further configured to delete the connection information from the memory during a power-down of the processing apparatus.

US Pat. No. 10,368,234

METHOD AND APPARATUS FOR SENDING AND RECEIVING MULTI-CARRIER INFORMATION IN MULTI-CARRIER COMMUNICATION SYSTEM

LG ELECTRONICS INC., Seo...

1. A method for operating a plurality of carriers by a user equipment in a wireless communication system supporting a primary carrier and at least one secondary carrier, the method comprising:transmitting, to a first base station, carrier capability information;
receiving, from the first base station, carrier configuration information, the carrier configuration information including an index of the at least one secondary carrier configured for the user equipment, the carrier configuration information being based upon the carrier capability information of the user equipment, the primary carrier being configured as a carrier for performing an initial network entry procedure;
receiving, from the first base station through the primary carrier, a control channel, the control channel including control information for traffic exchanged via a secondary carrier between the user equipment and the first base station;
receiving, from the first base station, traffic through the secondary carrier based on the control channel received through the primary carrier; and
receiving a message during a procedure of network entry to a second base station, the message including information for a primary carrier change,
wherein the primary carrier is only changed with the procedure of network entry.

US Pat. No. 10,368,232

METHODS FOR CONNECTION CAPABILITY EXCHANGE

QUALCOMM Incorporated, S...

1. A method of communicating in a wireless communication network, comprising:transmitting, by a first wireless device, a connection capability request message to a second wireless device requesting connection capability information of the second wireless device;
receiving, by the first wireless device, a connection capability response message from the second wireless device indicating one or more communication protocols available for providing a service to the first wireless device,
wherein the connection capability request message and the connection capability response message comprise a first discovery protocol;
selecting, by the first wireless device, based at least in part on the connection capability response message, a communication protocol of the one or more communication protocols for obtaining the service from the second wireless device; and
performing a second discovery protocol based on the connection capability response message.

US Pat. No. 10,368,230

DATA ENHANCEMENTS FOR ESIM PROFILE OPERATION CALLBACKS

T-Mobile USA, Inc., Bell...

1. One or more non-transitory computer-readable media storing computer-executable instructions that upon execution cause one or more processors to perform acts comprising:sending a command for a machine-to-machine (M2M) device to perform an operation on an embedded subscriber identity module (eSIM) profile stored in an embedded universal integrated circuit card (eUICC) of the M2M device, the operation being request by a backend service of a wireless communication carrier;
receiving a confirmation message from the M2M device indicating that the operation on the eSIM profile is performed; and
sending a callback message to the backend service of the wireless communication carrier indicating that the operation is performed, the callback message including an eUICC identifier (ID) of the eUICC or an Integrated Circuit Card identifier (ICCID) of the eSIM profile, the eUICC ID or the ICCID being used by the backend service to locate a profile state entry of the eSIM profile in an eSIM profile state database for update with a profile state of the eSIM profile after the operation.

US Pat. No. 10,368,225

LOCATION DETERMINATION FOR A SERVICE REQUEST

Microsoft Technology Lice...

1. A method comprising:receiving, over a network from a communication client implemented at a client device, data corresponding to a service request;
obtaining a registered location of the communication client, an updated location of the client device, and a reliability metric indicating a reliability of the updated location of the client device;
comparing the updated location of the client device to the registered location of the communication client to determine that the updated location is different than the registered location; and
determining whether to route the data of the service request along with the updated location to an answering point based on whether the reliability metric for the updated location is above a reliability threshold, including:
routing the data of the service request along with the updated location to the answering point based on determining that the reliability metric is above the reliability threshold; or
determining that the updated location cannot reliably be determined based on determining that the reliability metric is below the reliability threshold.

US Pat. No. 10,368,224

MULTIMEDIA FOR WIRELESS EMERGENCY ALERTS

1. An apparatus comprising:a processor; and
a memory coupled with the processor, the memory comprising executable instructions that when executed by the processor cause the processor to effectuate operations comprising:
receiving a wireless emergency alert and an indication of availability of multimedia content associated with the wireless emergency alert;
mapping target cells for the wireless emergency alert;
sending information comprising the wireless emergency alert with the indication of availability of multimedia content and coordinates of a emergency to a broadcast multicast service center for distribution to the target cells and a first mobile device, wherein the first mobile device determines whether to display the wireless emergency alert based on the coordinates of the emergency compared to a location of the first mobile device;
obtaining the multimedia content based on the instructions from the first mobile device, wherein the multimedia content is obtained from a gateway; and
providing instructions to the first mobile device to retrieve the multimedia content from a second mobile device that is in proximity to the first mobile device.

US Pat. No. 10,368,222

SELF-DIRECTING NODE

Intel Corporation, Santa...

1. A node which when caused to move in an environment including one or more machines capable of moving the node based at least in part on a persistent output of the node, comprising:a manifest indicating at least sensor constraints associated with the node; at least one sensor to periodically determine sensor readings associated with the node; a node status having a value set based at least in part on a comparison of selected sensor readings with at least the manifest; the persistent output providing at least a first destination indicator for the node determined based at least in part on the node status, and providing at least a second destination indicator for the node based at least in part on a change in the node status; a persistent memory; and
a power source for intermittently powering selected portions of the node.

US Pat. No. 10,368,220

METHOD AND ARRANGEMENTS FOR MTC COMMUNICATION

TELEFONAKTIEBOLAGET LM ER...

1. A server apparatus for communicating with user machine type communication (MTC) devices, the server apparatus being arranged to:determine whether a user MTC device does not have an IP connection with a cellular access network (CAN);
determine whether the user MTC device is a stationary user MTC device; and
trigger the user MTC device to initiate an IP connection with the CAN, wherein
the server apparatus is configured such that the server apparatus triggers the user MTC device to initiate the IP connection with the CAN if and only if the server apparatus determines (a) that the user MTC devices is a stationary device and (b) that the user MTC device does not have the IP connection, wherein
the server apparatus is further configured such that, after triggering the user MTC device to initiate the IP connection with the CAN, the server apparatus monitors the user MTC device to detect whether the user MTC device has acquired the IP connection,
the server apparatus is further configured such that, after the server apparatus detects that the user MTC has acquired the IP connection, the server apparatus causes the user MTC device to initiate an application,
the server apparatus is configured to cause the user MTC device to initiate the application by transmitting to the user MTC device an application triggering message, and
the server apparatus is further configured such that, after triggering the user MTC device to initiate the IP connection with the CAN, the server apparatus waits until it has received confirmation that the user MTC has established the IP connection before the server apparatus transmits the application triggering message.

US Pat. No. 10,368,219

SYSTEM AND METHOD FOR EUICC PERSONALIZATION AND NETWORK PROVISIONING

Verizon Patent and Licens...

1. A method, comprising:receiving, by a primary user device, input to initiate a cellular service activation process for a companion device, wherein the companion device includes a preloaded version of a service provider application for facilitating remote provisioning;
providing, by the primary user device and to the companion device, an updated version of the service provider application that replaces the preloaded version;
receiving, by the primary user device, and from the companion device, an embedded universal integrated circuit card (eUICC) identifier for the companion device;
forwarding, by the primary user device and to a network device in a service provider network, the eUICC identifier and an identifier for the primary user device; and
when the network device verifies that the cellular service activation for the companion device can be provisioned under a subscriber account:
receiving, by the primary user device and from the network device, an activation code for the companion device to use to initiate a request for a new line of service for the eUICC identifier; and
forwarding, by the primary user device and to the companion device, the activation code.

US Pat. No. 10,368,218

SPATIALLY AWARE VIRTUAL WORKOUT ASSISTANT

International Business Ma...

1. A method for a spatially aware virtual workout assistant, the method comprising:receiving from a mobile device, by a server, a view of a surrounding environment of a user, the view being captured by the mobile device;
extracting, by the server, one or more elements from the view;
recognizing, by the server, one or more objects suitable for exercising, based on the one or more elements, by using a model for visual data recognition;
determining, by the server, one or more exercises that can be performed with the one or more objects, by searching datasets in the server;
sending to the mobile device, by the server, data associated with the one or more objects and the one or more exercises;
wherein the mobile device instructs the user to locate the one or more devices and to perform the one or more exercises, based on the data associated with the one or more objects and the one or more exercises and
wherein the datasets include a dataset correlating a user goal and workouts, a dataset correlating the workouts and the one or more exercises, a dataset correlating the one or more exercises and the one or more objects, a dataset correlating the workouts and calories burned, and a dataset correlating the workouts and time spent for the one or more exercises.

US Pat. No. 10,368,215

HYBRID NETWORK BASED METERING SERVER AND TRACKING CLIENT FOR WIRELESS SERVICES

TracFone Wireless, Inc., ...

1. A process of tracking usage of a wireless device in a wireless network with a metering system comprising:implementing the metering system in a network separate from the wireless network;
receiving with the metering system identification information from the wireless device implementing a tracking client;
receiving usage statistics with the metering system from the tracking client implemented in the wireless device;
receiving with the metering system an amount of wireless services used by the wireless device determined by the wireless network; and
comparing with the metering system the amount of wireless services used by the wireless device determined by the wireless network to the amount of wireless services used by the wireless device received from the tracking client of the wireless device; and
controlling with the metering system access to the wireless network for the wireless device based in response to the amount of wireless services used by the wireless device.

US Pat. No. 10,368,214

OVER THE AIR PROVISIONING OF MOBILE DEVICE SETTINGS

1. A method, comprising:providing, by an application download server to a mobile device, an application including executable instructions which, when executed by a processor of the mobile device,
(i) cause the mobile device to transmit an activation request for wireless communication services;
(ii) cause the mobile device to be activated for use with any one of a plurality of mobile network carriers, the one of the plurality of mobile network carriers being selected by a user of the mobile device from a user interface at the mobile device, the user interface presenting a plurality of mobile network carrier options from which the user may select the one of the plurality of mobile network carriers,
(iii) enable access by the mobile device of wireless communication services provided by the one of the plurality of mobile network carriers for which the mobile device has been activated, and
(iv) enable the user of the mobile device to select from the user interface one or more service plans associated with the selected one of the plurality of mobile network carriers, the user interface presenting a plurality of service plan options from which the user may select the one or more service plans,
wherein the application is provided to the mobile device by an entity that is not one of the mobile network carriers;
transmitting application download event information to a transaction manager, the transaction manager including at least one processor; and
determining, by the transaction manager, one or more usage records for the wireless communication services.

US Pat. No. 10,368,213

LOCATION-BASED OPEN SOCIAL NETWORKS

1. An apparatus having stored executable instructions, comprising:1) at least one computing system being operable to implement a social networking system, the social networking system implementing a plurality of social networks;
2) the plurality of social networks each accessible without registration requirements;
3) the social networking system arranged to select a given number of first social networks among the plurality of social networks after receiving a request from a user, the first social networks each having virtual reality or augmented reality content that has more viewers than virtual reality or augmented reality content provided at each of rest of the plurality of social networks; and
4) the social networking system arranged to send the user information about the first social networks.

US Pat. No. 10,368,211

CONVERSATION ASSISTANT

1. A computer-implemented method comprising:engaging, by a first application, in an interactive chat communication session with a user of a telephonic device;
identifying, by the first application, data indicative of prior interactions with one or more applications accessed via the telephonic device;
identifying, based on the identified data and based on the interactive chat communication session with the user, a service or a product that is likely to be of interest to the user of the telephonic device;
identifying a second application associated with the identified service or the identified product for recommendation to the user;
providing, by the first application, the recommendation for the identified second application;
determining whether the user has accepted the recommendation;
in response to determining that the user has accepted the recommendation, transmitting a signal to download the second application onto the telephonic device; and
executing the second application, by the first application, for enabling the user to receive the identified service or the identified product,
wherein the identified second application comprises a software application that includes instructions executable by the first application to perform a call flow, and
wherein the call flow comprises a sequence of at least two prompt instructions and at least two grammar instructions executable to result in a simulated multi-step spoken conversation between the first application and the user, each of the at least two prompt instructions being executable to ask for information from the user and each of the at least two grammar instructions being executable to interpret information spoken to the telephonic device by the user.

US Pat. No. 10,368,209

ROUTING MULTIPLE NUMBERS FOR ONE TELECOMMUNICATIONS DEVICE

T-Mobile USA, Inc., Bell...

1. A method comprising, by a core network device:receiving from a call-originating device a first initiation request of a communication session to an alias number;
retrieving from a registration database one or more destination number(s) corresponding to the alias number; the retrieving comprising:
transmitting to the registration database a Send Routing Information (SRI) request corresponding to the alias number, and
receiving, from the registration database, at least one of the destination number(s) including an Internet Protocol (IP) Multimedia Subsystem (IMS) Routing Number (IMRN);
transmitting respective intent message(s) to destination(s) corresponding to the retrieved destination number(s), each intent message of the intent message(s) comprising a respective indication of the alias number; and
transmitting a second initiation request associated with the communication session to one of the destination(s) using the respective one of the retrieved destination number(s).

US Pat. No. 10,368,207

CLOSED USER GROUPS

1. A method, comprising:receiving, by a network device, an identifier of a closed user group;
querying, by the network device, an electronic database for the identifier of the closed user group, the electronic database electronically associating member Internet protocol addresses of closed user groups to different group-specific ping commands including the identifier of the closed user group;
identifying, by the network device from the electronic database, a group-specific ping command of the different group-specific ping commands that is electronically associated with the identifier of the closed user group;
identifying, by the network device from the electronic database, the member Internet protocol addresses that are electronically associated with the identifier of the closed user group; and
broadcasting, by the network device, the group-specific ping command as a locational request to each one of the member Internet protocol addresses associated with the identifier of the closed user group.

US Pat. No. 10,368,205

PROVIDING, ORGANIZING, AND MANAGING LOCATION HISTORY RECORDS OF A MOBILE DEVICE

QUALCOMM Incorporated, S...

1. A method of providing information associated with a location history of a mobile device to one or more applications, comprising:generating, by at least one processor of the mobile device, a plurality of location history records corresponding to a plurality of locations of the mobile device, wherein each location history record of the plurality of location history records comprises a location of the mobile device and a time at which the mobile device was at the location;
storing, in a local memory of the mobile device, the plurality of location history records;
receiving, at the processor of the mobile device, subsequent to storing the plurality of location history records, a first information request from a first application of the one or more applications, the first information request including a first set of criteria for filtering the plurality of location history records;
determining, by the at least one processor of the mobile device, a first subset of the plurality of location history records that meet the first set of criteria; and
providing, by the at least processor of the mobile device, information associated with the first subset of the plurality of location history records to the first application based on a first level of permission of the first application and the first set of criteria.

US Pat. No. 10,368,203

SYSTEM AND A METHOD FOR ENTITY TRACKING

COGNIZANT TECHNOLOGY SOLU...

1. A tracking device for tracking one or more entities positioned at any location or moving through one or more transit points, the tracking device interfacing with one or more sources associated with the entity, the tracking device comprising:a memory storing program instructions; a processor configured to execute program instructions stored in the memory; and a data acquisition and message generation engine in communication with the processor and configured to:
receive one or more types of signaling functions associated with the entity from one or more sources in response to a code generated by an action performed on a transmitter device associated with the entity, wherein the code comprises a transmitter ID associated with an entity ID of the entity;
evaluate time difference between the time of receiving the code and time of occurrence of the at least one type of signaling functions in respect to a predetermined time difference, wherein computing the time of occurrence of the at least one type of signaling function comprises:
retrieving time of occurrence of the at least one signaling function from a first record of the signaling function;
retrieving time of occurrence of the at least one signaling function from a second record of the signaling function;
mapping the first record of the at least one signaling function with the second record of the at least one signaling function; and
computing exact time of occurrence of the at least one signaling function by comparing the time of occurrences retrieved from the first and the second records based on a predetermined time lag;
generate a timestamped record of at least one type of signaling function in response to the results of the evaluation; and
generate an event message for creating a tracking file by processing the received code with tracking data, wherein the tracking data comprises one or more parameters associated with the entity and tracking device.

US Pat. No. 10,368,200

DEVICE AND METHOD FOR POSITION MEASUREMENT IN WIRELESS COMMUNICATION SYSTEM

Samsung Electronics Co., ...

1. An apparatus for a terminal in a wireless communication system, the apparatus comprising:a transceiver; and
at least one processor operatively coupled with the transceiver,
wherein the at least one processor is configured to:
transmit a first signal for requesting positioning,
receive positioning signals for positioning of the terminal from a first plurality of other terminals, the first plurality of other terminals comprising at least one position determined terminal with a determined position and an expiration time for the determined position,
determine distance values between the terminal and the first plurality of other terminals based on the positioning signals, and
if at least one of the distance values is greater than or equal to a threshold value, transmit a second signal for requesting positioning for receiving other positioning signals from a second plurality of other terminals except terminals whose expiration time has elapsed.

US Pat. No. 10,368,196

SUPPRESSING NOTIFICATIONS BASED ON DIRECTED LOCATION ACTIVITY

International Business Ma...

1. A method comprising:determining that a location based event has occurred, the location based event pertaining to a certain user computer device;
identifying, based on the determining, a notification for sending to the certain user computer device, wherein the notification has an associated destination location;
examining an activity level of the destination location; and
based on the activity level exceeding a threshold, providing one or more output, wherein the one or more output includes an output to suppress sending the notification, and an output to initiate an alternate process, the alternate process including sending an alternate notification to the certain user computer device, the alternate notification prompting the certain user to travel to a second destination location that is spaced apart from the destination location.

US Pat. No. 10,368,195

ELECTRONIC DEVICE IN WIRELESS COMMUNICATION SYSTEM AND WIRELESS COMMUNICATION METHOD

Sony Corporation, Tokyo ...

1. An electronic device in a wireless communication system, comprising one or more processing circuits configured to:acquire an on/off state of a small cell base station within a predetermined geographical region; and
generate, based on the acquired on/off state of the small cell base station, reconfiguration information of a positioning reference signal PRS for the small cell base station within the predetermined geographical region, to position a user equipment within the predetermined geographical region, wherein
the reconfiguration information of the PRS comprises a PRS transmission period of an on small cell base station, and the processing circuits are further configured to adjust the PRS transmission period of the on small cell base station based on a ratio of the number of off small cell base stations within the predetermined geographical region to the number of small cell base stations within the predetermined geographical region.

US Pat. No. 10,368,193

TECHNIQUES FOR SHARING A DEVICE LOCATION VIA A MESSAGING SYSTEM

FACEBOOK, INC., Menlo Pa...

1. A method comprising:receiving, in a messaging client executing on a first client device, a location request from a second client device requesting a location of the first client device;
determining whether the second client device is authorized to receive the location of the first client device, the second client device being automatically authorized to receive the location when a user of the second client device and a user of the first client device are both participants in a common messaging thread;
starting a timer in response to receiving the location request when the second client device is authorized; and
sending the location of the first client device to the second client device when the timer expires.

US Pat. No. 10,368,191

CONFINED SPACE ESTIMATION SYSTEM AND CONFINED SPACE ESTIMATION METHOD

HITACHI, LTD., Tokyo (JP...

1. A confined space estimation system which estimates a confined space, comprising:a storage device which stores information indicating a geographical space; and
a processor which divides the geographical space into a plurality of grids,
wherein, based on location information sent from a terminal, the processor:
periodically aggregates a number of terminals within the grids or a number of terminals that passed through boundaries between the grids;
extracts grids or boundaries in which the aggregated number of terminals is a predetermined number and in which there is no change in the aggregated number of terminals;
determines whether the extracted grids or boundaries can be linked to form an annular shape; and
estimates, if the annular shape can be formed, a geographical space configured from the grids within the formed annular shape as the confined space
wherein, upon determining whether the extracted grids can be linked to form an annular shape, the processor:
sets one grid among the extracted grids as a start node and an end node, sets other grids other than the start node and the end node as intermediate nodes, and determines whether the annular shape can be formed by searching for a shortest path from the start node to the end node via any one of or all of the intermediate nodes.

US Pat. No. 10,368,190

PHYSICAL AND VIRTUAL PHONE MOBILITY

Microsoft Technology Lice...

1. A computing device configured to optimize operations of a mobile device, the computing device comprising:one or more processors; and
one or more machine-readable memory devices storing instructions for execution by the one or more processors, in which the executed instructions cause the computing device to:
determine whether a location of the mobile device is within physical or logical proximity to the computing device,
responsive to the determination that the mobile device is within the physical or logical proximity to the computing device, provide one or more controls on a user interface of the computing device to a user,
wherein the provided one or more controls enable user control over migration of one or more tasks associated with an application from the mobile device to the computing device and further enable user control over allocation of computing resources between the mobile device and the computing device;
transfer at least partial operation of the application from the mobile device to the computing device by migrating the one or more tasks associated with the application in response to the user control; and
allocate the computing resources in response to the user control.

US Pat. No. 10,368,189

DEVICE AND METHOD FOR DIRECTING EMPLOYEE MOVEMENT

WALMART APOLLO, LLC, Ben...

1. A mobile computing device for directing motion, the mobile computing device comprising:a proximity detection module, wherein the mobile computing device for directing motion is a first mobile computing device, and wherein the proximity detection module receives a coverage signal transmitted by a second mobile computing device;
a motion detection module, wherein the motion detection module detects whether the first mobile computing device and/or the second mobile computing device are in motion;
and
a direction module, wherein the direction module outputs a motion direction instruction in response to:
the proximity detection module receiving the coverage signal transmitted by the second mobile computing device; and
the motion detection module detecting the first mobile computing device and the second mobile computing device are both in motion; and
wherein the direction module does not output the motion direction instruction when one of the first mobile computing device and the second computing device are not in motion.

US Pat. No. 10,368,187

SYSTEMS AND METHODS FOR IDENTIFYING AVAILABLE LOCATION-BASED SERVICES

Walmart Apollo, LLC, Ben...

1. A system for identifying available location-based services, the system comprising:a mobile application executable on a mobile computing device operated by a user;
a database storing one or more previously ordered services associated with the user, wherein the one or more previously ordered services are pending services that are not yet complete due to the services requiring an interaction of the user with a physical facility;
a plurality of location-specific computing devices located at a plurality of locations within a facility that are configured to use location-based wireless communication to transmit a code to the mobile application that identifies types of services available to be performed at a location of a location-specific computing device, at least one available service differing between two of the plurality of locations, wherein the available types of services are location-based services capable of being performed at a location of a location-specific computing device;
a machine-readable element configured to provide location information used in initiating performance of one or more available ordered services; and
a server communicatively coupled to the database and the mobile application and hosting a services management framework configured to map the one or more previously ordered services to the one or more available types of services to determine one or more available ordered services at a location of a location-specific computing device, wherein the one or more available ordered services are ordered services capable of being performed at a location of a location-specific computing device,
wherein the mobile application is configured to:
receive a code from a first location-specific computing device of the plurality of location-specific computing devices;
identify one or more available types of services based on the code;
transmit, to the services management framework, the identification of the one or more available types of services and user authentication data;
receive an indication from the services management framework of the one or more available ordered services;
decode the machine-readable element to decode location information; and
initiate performance of at least one of the one or more available ordered services determined by the services management framework using the decoded location information.

US Pat. No. 10,368,186

TOOL TRACKING SYSTEM

Milwaukee Electric Tool C...

1. A signaling method for communicating and logging a location of an object, the method comprising:transmitting repeatedly, by a beacon transmitter, a first beacon signal through a first number of transmission repetitions spaced at a first repeat interval;
responsive to receiving the first beacon signal, activating, by an electronic processor of a personal wireless device, a dormant transmitter location logging application;
withholding transmission, by the beacon transmitter, during a transition interval that occurs after completing the first number of transmission repetitions;
transmitting repeatedly, by the beacon transmitter, a second advertising beacon signal through a second number of transmission repetitions at a second repeat interval;
responsive to receiving the second advertising beacon signal, logging to a memory of the personal wireless device, an identifier of a beacon transmitter that transmitted the second advertising beacon signal;
determining, by the personal wireless device, the location of the personal wireless device; and
associating, in the memory of the personal wireless device, the location of the personal wireless device with the beacon transmitter identifier.

US Pat. No. 10,368,185

MOBILE DEVICE LOCATION PROOFING

International Business Ma...

1. A computer-implemented method of verifying a location of a mobile device, the method comprising:receiving, on the computer, a first location report from a first mobile device, the first location report including a location identification for the first mobile device and pairing information identifying mobile devices with which the first mobile device is paired;
identifying at least one reference mobile device in the vicinity of the identified location of the first mobile device;
requesting from the at least one reference mobile device a reference location report including further pairing information identifying mobile devices with which the reference mobile device is paired;
receiving the reference location report from the at least one reference mobile device; and
evaluating the received reference location report to check whether the received reference location report verifies or does not verify the location identification in the first location report received from the first mobile device, including
verifying the location identification in the first location report received from the first mobile device by identifying the first mobile device in the further pairing information in the received at least one reference location report; and wherein:
the further pairing information identifies each of the mobile devices with which the reference mobile device is paired by a further device identifier; and
verifying the location identification in the first location report received from the first mobile device by identifying the first mobile device in the further pairing information in the received at least one reference location report comprises:
comparing a device identifier of the first mobile device with the one or more further device identifiers in the further pairing information.

US Pat. No. 10,368,184

ADVERTISING AND PROFILING USER LOCATION TO UNIFIED COMMUNICATION SUITE IN ENTERPRISE WIRELESS NETWORKS

Hewlett Packard Enterpris...

1. A non-transitory computer readable medium comprising instructions which, when executed by one or more hardware processors of a network device, cause the network device to perform multiple operations comprising:determining that a first user is logged on a wireless local area network (WLAN) and assigned a first user role during a first time, the first user role corresponding to a first set of network privileges, wherein the first user role is assigned and provided by the WLAN;
inferring a first status for the first user based at least on the first user role and a first user presence at a particular location for an amount of time during a predetermined period of time of day, wherein the first user presence is based on a first user role information provided by the WLAN;
displaying the first status for the first user during the first time;
subsequently assigning a second user role to the first user during a second time, the second user role corresponding to a second set of network privileges, wherein the second user role is assigned and provided by a policy engine in the WLAN, the policy engine configured to collect multiple user attributes for the first user from multiple identity stores and from a third party network to which the first user is subscribed;
determining a first client device corresponding to the first user is located at the particular location during the first time and the second time based at least on the second user role and the first user presence at the particular location for the amount of time during the predetermined period of time of day;
displaying a second status for the first user during the second time;
determining that the first client device is logged on to the WLAN via a virtual private network (VPN) connection for a third time period;
assigning a third user role based on the VPN connection, wherein the third user role corresponds to a third set of network privileges; and
displaying a third status for the first user during the third time.

US Pat. No. 10,368,183

DIRECTIVITY OPTIMIZED SOUND REPRODUCTION

Apple Inc., Cupertino, C...

6. An article of manufacture, comprising: a non-transitory machine-readable storage medium that stores instructions which, when executed by a processor in a server, determine a first directivity pattern for each channel of a multi-channel dialogue signal for a piece of sound program content, the first directivity pattern characterized by a first directivity index; determine a second directivity pattern for each channel of a combined multi-channel music and effects signal for the piece of sound program content, the second directivity pattern characterized by a second directivity index, the second directivity index being less than the first directivity index, the first directivity pattern and second directivity pattern being included in metadata; transmitting, by the server to an audio receiver, a) the multi-channel dialogue signal, b) the combined multi-channel music and effects signal, and c) the metadata, wherein the audio receiver generates a first set of processed audio signals for the channels of the combined multi-channel dialogue signal for transducers in a speaker array to produce sound of the multi-channel dialogue signal having the first directivity pattern, and generates a second set of processed audio signals for the channels of the combined multi-channel music and effects signal for the transducers in the speaker array to produce sound of the combined multi-channel music and effects signal having the second directivity pattern.

US Pat. No. 10,368,182

DEVICE AND METHOD OF MODIFYING AN AUDIO OUTPUT OF THE DEVICE

YANDEX EUROPE AG, Lucern...

1. A method of selectively modifying an initial audio output of a device, the device comprising at least two speakers communicatively coupled to a processor, the method comprising:detecting, by the processor, a volume level of the initial audio output reproducible by the at least two speakers;
comparing, by the processor, the volume level to a volume level threshold;
based on the comparison of the volume level to the volume level threshold, controlling, by the processor, reproduction of the initial audio output by the at least two speakers by a selective execution of:
responsive to the volume level being inferior to the volume level threshold, transmitting, by the processor, an identical audio signal to each one of the at least two speakers for reproducing a modified audio output, the modified audio output being of a mono audio output type; and
responsive to the volume level being superior to the volume level threshold, transmitting, by the processor, respective audio signals to the at least two speakers for reproducing the modified audio output, the respective audio signals being different from one another, the modified audio output being of a stereo audio output type.

US Pat. No. 10,368,181

LOUDNESS ADJUSTMENT FOR DOWNMIXED AUDIO CONTENT

Dolby Laboratories Licens...

1. A method for gain adjusting audio signals based on encoder-generated loudness metadata, the method comprising:receiving, by an audio decoder operating in a playback channel configuration different from a reference channel configuration, an audio signal for the reference channel configuration, the audio signal including audio sample data for each channel of the reference channel configuration, and the encoder-generated loudness metadata, the encoder-generated loudness metadata comprising loudness metadata for a plurality of channel configurations including the playback channel configuration and the reference channel configuration;
selecting, from the loudness metadata for the plurality of channel configurations, the loudness metadata for the playback channel configuration;
determining loudness adjustment gains from the loudness metadata for the playback channel configuration; and
applying the loudness adjustment gains as a part of overall gains applied to the audio sample data to generate output audio sample data for each channel of the playback channel configuration;
wherein the loudness adjustment gains depend on a loudness level indicated by the loudness metadata for the playback channel configuration and a reference loudness level.

US Pat. No. 10,368,179

SWITCHING BINAURAL SOUND

14. A method executed by one or more electronic devices, the method comprising:storing head-related transfer functions (HRTFs) in memory;
displaying, with a wearable electronic device (WED) worn on a head of a user, a virtual image in an environment;
processing, by a digital signal processor (DSP), sound with the HRTFs to generate binaural sound that externally localizes in empty space from the virtual image in the environment;
determining, with the WED, when the user is leaving the environment; and
alerting the user that the user is leaving the environment by reducing a volume of the binaural sound that localizes from the virtual image and that is being provided to the user.

US Pat. No. 10,368,177

ABNORMALITY DETECTING DEVICE, ABNORMALITY DETECTION METHOD, AND RECORDING MEDIUM STORING ABNORMALITY DETECTION COMPUTER PROGRAM

FUJITSU LIMITED, Kawasak...

1. An abnormality detecting device comprising:a memory; and
a processor coupled to the memory and configured to:
detect an envelope of an audio signal indicating a periodic sound emitted by a target object and a periodic sound emitted by another object;
execute time-to-frequency conversion on the envelope to calculate a frequency spectrum of the audio signal; and
determine whether or not the target object has an abnormality, based on a frequency component included in the frequency spectrum and corresponding to a time interval between time points when the sound is emitted by the target object,
wherein the target object is a rotating device having a predetermined number of blades, and
wherein the processor is further configured to detect multiple peaks of the frequency spectrum, calculate, for each of combinations, each of which includes two peaks among the multiple peaks, the ratio of a frequency corresponding to one of two peaks included in the combination to a frequency corresponding to the other of the two peaks included in the combination, and estimate, as a frequency corresponding to the time interval between the time points when the sound is emitted by the target object, lower one of frequencies corresponding to two peaks included in a combination that is among the combinations and causes the difference between the ratio of the frequencies corresponding to the peaks of the combination and the predetermined number of blades to be the smallest among differences between the ratios calculated for the combinations and the predetermined number of blades.

US Pat. No. 10,368,175

HEARING DEVICE COMPRISING A FEEDBACK DETECTION UNIT

1. A hearing device comprising a forward path for processing an electric signal representing sound, the forward path comprisingan input unit for receiving or providing an electric input signal representing sound,
a signal processing unit for applying a frequency- and/or level-dependent gain to an input signal of the forward path and providing a processed output signal, and
an output transducer for generating stimuli perceivable as sound to a user;
the hearing device further comprising
a feedback detection unit configured to detect feedback or evaluate a risk of feedback via an acoustic or mechanical or electrical feedback path from said output transducer to said input unit,
a loop consisting of said forward path and said feedback path being defined, the loop exhibiting a loop delay D,
wherein said feedback detection unit comprises
a magnitude and phase analysis unit for repeatedly determining magnitude and phase of said electric input signal or a processed version thereof, and further configured to determine values of loop magnitude, loop phase, loop magnitude difference, and loop phase difference signals, respectively, based thereon and on said loop delay D, where said loop magnitude difference and said loop phase difference are the differences between values of the parameters, loop magnitude and loop phase, respectively, at a given time instant, m, and a time instant, mD, one feedback loop delay D earlier;
a feedback conditions and detection unit configured to check criteria for magnitude and phase feedback condition, respectively, based on said values of loop magnitude, loop phase, loop magnitude difference, and loop phase difference signals, respectively, and to provide feedback detection signal indicative of feedback or a risk of feedback.

US Pat. No. 10,368,174

DISTRIBUTED PHASE LOCKED LOOP IN HEARING INSTRUMENTS

SEMICONDUCTOR COMPONENTS ...

1. A system, comprising:a receiver configured to receive wireless signals from an electronic device, the receiver comprising:
receiver logic operable to receive an input signal at a source clock frequency from the electronic device;
a phase detector coupled to the receiver logic and operable to:
receive a data sampling clock; and
compute an error signal indicating a difference between the data sampling clock and the source clock; and
a first communication interface coupled to the phase detector and operable to transmit the input signal; and
a signal processor (SP) coupled to the receiver and comprising:
a second communication interface operable to couple to the first communication interface to communicatively couple the SP to the receiver;
a digitally-controlled oscillator (DCO) coupled to the second communication interface and operable to generate a system clock;
a clock divider coupled to the DCO and the phase detector and operable to generate the data sampling clock based at least partially on the system clock; and
digital signal processing logic coupled to the DCO and the clock divider and operable to process the input signal at a frequency specified by the data sampling clock.

US Pat. No. 10,368,169

POWER AND BANDWIDTH EFFICIENT TRUE WIRELESS STEREO SPEAKERS

QUALCOMM Incorporated, S...

1. A method for wireless communication at a first speaker, comprising:establishing a control communication link with a second speaker over a first piconet;
receiving, in a first slot of an extended synchronous connection-oriented (eSCO) window on a second piconet, a first null signal sent from a wireless device to the second speaker;
switching, in a second slot of the eSCO window that is consecutive to the first slot, and based at least in part on the first null signal, from the second piconet to the first piconet;
transmitting to the second speaker, on the first piconet, a second null signal based at least in part on the first null signal; and
closing the eSCO window based at least in part on the second null signal.

US Pat. No. 10,368,166

VOLTAGE REGULATOR AND CONTROL CIRCUIT FOR SILVER-ZINC BATTERIES IN HEARING INSTRUMENTS

ZPower, LLC, Camarillo, ...

1. An apparatus for managing power within a voltage regulating circuit of a battery-powered hearing aid device, comprising:an input terminal of a voltage regulator receiving an input voltage (VIN) supplied by a battery;
an output terminal of the voltage regulator providing an output voltage (VOUT) to a hearing aid terminal electrically connected to one or more electrical components of the hearing aid device, the output voltage (VOUT) based on the input voltage (VIN);
a sensing terminal of the voltage regulator for sensing a charging current (VSENSE) between a charging device and charging contacts of the voltage regulating circuit; and
a switch device configured to:
transition to an ON state to allow the charging device to charge the battery based on the sensing terminal of the voltage regulator sensing the charging current (VSENSE) between the charging device and the charging contacts; and
transition to an OFF state to block the charging contacts from receiving voltage from the battery when the output voltage (VOUT) is present;
wherein the voltage regulator is configured to reduce a magnitude of the input voltage (VIN) when the magnitude of the input voltage (VIN) exceeds an input voltage threshold (Vin_thresh) to generate the output voltage (VOUT) having a magnitude that is less than a maximum output voltage (Vout_max) and is further configured not to downregulate the input voltage (VIN) when the magnitude of the input voltage (VIN) is not greater than the input voltage threshold (Vin_thresh).

US Pat. No. 10,368,163

HEADSET POWER SUPPLY AND INPUT VOLTAGE RECOGNITION

QUALCOMM Incorporated, S...

1. An electronic apparatus, comprising:a detection circuit configured to recognize a user input voltage generated by an electronic user input, the detection circuit comprising a reference voltage generator including a multiplexer configured to generate a set of reference voltages in a sequence for comparing with the user input voltage generated by the electronic user input, the multiplexer controlled by multiplexer selection signals from a counter to cause the multiplexer to multiplex the set of reference voltages, the detection circuit including a comparator comprising an auto-zero amplifier configured to compare the set of reference voltages and the user input voltage, the auto-zero amplifier comprising:
an operational amplifier;
a first switch coupled between an output of the operational amplifier and an input of the operational amplifier;
a capacitor having a first lead coupled to the input of the operational amplifier and coupled to the first switch;
a second switch configured to selectively couple the reference voltages to a second lead of the capacitor; and
a third switch configured to selectively couple a user input voltage to the second lead of the capacitor; and
a power supply configured to supply power to the detection circuit.

US Pat. No. 10,368,153

WATERPROOF SOUND-TRANSMITTING MEMBRANE AND WATERPROOF SOUND-TRANSMITTING STRUCTURE USING THE SAME

NITTO DENKO CORPORATION, ...

1. A waterproof sound-transmitting membrane comprising a sound-transmitting region consisting of a single porous membrane of polytetrafluoroethylene, the porous membrane having a through-thickness air permeability of 2 cm3/cm2/s or more as measured by Method A (Frazier method) for air permeability measurement according to Japanese Industrial Standards (JIS) L 1096 and a water entry pressure of 3 kPa or more as measured by Method B (high hydraulic pressure method) for waterproofness testing according to JIS L 1092,wherein the waterproof sound-transmitting membrane has a sound distortion of 60.2% or less, and
wherein the porous membrane has a water entry pressure of 20 kPa or more and 50 kPa or less.

US Pat. No. 10,368,151

EXTERIOR COVER WITH SPEAKER

Samsung Electronics Co., ...

1. An exterior cover for protecting a display of an electronic device, the exterior cover comprising:a cover portion configured to foldably connect to the electronic device in a first end of the cover portion, the cover portion comprising:
segments comprising:
a first segment located at a first end of the cover portion,
a second segment located at a second end of the cover portion opposite the first end, and
a third segment located between the first segment and the second segment; and
a folding axis allowing the segments to fold with respect to each other such that the folded segments support the electronic device in a cradle position when the electronic device is inclined at a first angle,
wherein the first segment comprises a first speaker, the second segment comprises a second speaker, and the third segment comprises a third speaker,
wherein the first speaker comprises a vibration plate and the first segment is in contact with a ground when the electronic device is in the cradle position, and
wherein the vibration plate reproduces sound at a low frequency band, and the second speaker and the third speaker reproduce sound at higher frequency bands.

US Pat. No. 10,368,147

SERVICE AVAILABILITY MONITOR

Schweitzer Engineering La...

1. A service availability monitor comprising:a monitoring subsystem configured to interface with a plurality of monitored services and to determine an availability of the plurality of monitored services provided at a service location at a plurality of times;
a logging subsystem configured to create a log representing the availability of the plurality of monitored services;
an alert subsystem configured to generate a first user notification of an interruption of the plurality of monitored services;
a redundant communication subsystem comprising:
a first communication interface in communication with a first communication channel, and
a second communication interface in communication with a second communication channel, each of the first communication interface and the second communication interface comprising a wired connection capable of propagating electronic signals,
wherein the redundant communication subsystem is configured to transmit the first user notification from the service location to a remote location using the first communication interface when the monitoring subsystem determines that the second communication channel is unavailable, and to transmit the first user notification from the service location to the remote location using the second communication interface when the monitoring subsystem determines that the first communication channel is unavailable, the service location being physically separated from the remote location;
a redundant power source, comprising:
a primary power subsystem configured to draw power from a primary power source to power the service availability monitor; and
a backup power subsystem configured to draw power from the primary power subsystem and to provide power to the service availability monitor when power is unavailable through the primary power subsystem.

US Pat. No. 10,368,144

METHOD AND DEVICE FOR TRANSMITTING AND RECEIVING BROADCAST SIGNAL

LG ELECTRONICS INC., Seo...

1. A method for transmitting a broadcast signal by a broadcast transmitter, the method comprising:generating video data that correspond to at least one of SD resolution, HD resolution, and UHD resolution;
generating Extensible Mark-up Language (XML) subtitle data of XML subtitles that is associated with a single resolution of the video data, the XML subtitle data including subtitle text and subtitle metadata, the subtitle metadata including base dynamic range information of the XML subtitles and supplementary dynamic range information of the XML subtitles for modifying a brightness of the XML subtitles when a resolution of the video data, that is displayed with the subtitle text, is different from the single resolution,
wherein the supplementary dynamic range information further includes contrast ratio information indicating a ratio of maximum luminance to minimum luminance;
multiplexing the video data and XML subtitle data; and
transmitting the generated broadcast signal including the multiplexed video data and XML subtitle data,
wherein the subtitle metadata further includes a base Electro-Optical Transfer Function (EOTF) element and a supplementary EOTF element for a dynamic range mapping of an original luminance value of the XML subtitles to a transferred luminance value, and
the subtitle metadata further includes base bitdepth information representing a first bitdepth and supplemental bitdepth information representing a second bitdepth which is different from the first bitdepth.

US Pat. No. 10,368,141

SYSTEM AND METHOD FOR ENGAGEMENT AND DISTRIBUTION OF MEDIA CONTENT

Dooreme Inc., Atlanta, G...

1. A system for distributing media content, the system comprising:a processor; and
a memory coupled to the processor, wherein the memory stores executable instructions for causing the processor to
present a mall interface on a display of a user system, the mall interface comprising a plurality of storefronts and a search function,
detect a user selection of the search function,
display a customized search result storefront based on the user selection,
present a selectable icon on the display of the user system, wherein the selectable icon is configured to be selected by a user through a control device,
subsequent to a user selecting the selectable icon, present on the display of the user system an engagement ad interface, wherein the engagement ad interface displays an engagement ad,
monitor whether the user watched the full duration of the engagement ad, and
provide a user a smart control comprising a selectable icon displayed on a mobile device and the display of the user system, wherein initiating the smart control on the display automatically launches a mobile application on the mobile device, and wherein initiating the smart control on the mobile application on the mobile device automatically launches the mall interface on the display.

US Pat. No. 10,368,137

SYSTEM FOR PRESENTING VIDEO INFORMATION AND METHOD THEREFOR

VUDU, INC., Sunnyvale, C...

1. A system comprising:one or more processors; and
one or more non-transitory computer readable media storing computing instructions configured to run on the one or more processors and perform acts of:
initiating a playback of an active media file on a screen of an electronic device;
during the playback of the active media file on the screen of the electronic device, receiving an instruction to enter an expanded view mode comprising an upward swiping motion on an expander displayed on a touch-sensitive display when the expander is closed;
responsive to receiving the instruction to enter the expanded view mode, and during the playback of the active media file on the screen of the electronic device, opening the expander displayed on the screen during the playback of the active media file, wherein:
the expander is configured, when open, to display an information mode and a poster mode on the screen at different times during the playback of the active media file;
the information mode is displayed, in response to the expander being open, as a default mode; and
the poster mode is displayed, in response to the expander being open, when a user selects an option in a preferences menu to set the poster mode as the default mode;
displaying the information mode on the screen at the expander during the playback of the active media file;
displaying the poster mode on the screen at the expander during the playback of the active media file;
receiving an instruction to end the expanded view mode; and
responsive to receiving the instruction to end the expanded view mode, and during the playback of the active media file on the screen of the electronic device, closing the expander on the screen, wherein:
the poster mode comprises a display of one or more graphical images representing one or more media files; and
displaying the information mode on the screen during the playback of the active media file comprises displaying at least one of synopsis information of the active media file, cast information of the active media file, rating information of the active media file, genre information of the active media file, length information of the active media file, or a year of release of the active media file.

US Pat. No. 10,368,136

RESOURCE MANAGEMENT FOR VIDEO PLAYBACK AND CHAT

Amazon Technologies, Inc....

1. A computer implemented method, comprising:receiving, by a resource controller of a viewer device, an indication that performance of a live streaming video playback of media content has experienced: dropped frames and a quality level of fragments of the media content requested from a media server has been downgraded;
reducing, by the resource controller, central processing unit (CPU) capacity allocated to a live chat concurrently provided with the live streaming video playback of the media content in response to the performance experiencing dropped frames; and
reducing, by the resource controller, bandwidth of a communication connection of the viewer device allocated to the live chat in response to the quality level being downgraded.

US Pat. No. 10,368,129

METHOD OF PROCESSING VIDEO DATA, DEVICE, COMPUTER PROGRAM PRODUCT, AND DATA CONSTRUCT

1. A video data processing device comprising:a processor, a non-transitory computer readable medium communicatively connected to the processor, and at least one sensor device communicatively connected to at least one of the processor and the non-transitory computer readable medium, the at least one sensor device configured to collect information relating to motions and gestures of at least one object;
the video data processing device configured to identify undesirable image contents contained in first video data based on a result of motion and gesture recognition that is based on the information relating to motions and gestures obtained via the at least one sensor device, said undesirable image contents including inappropriate body expression and provide content information relating to any identified undesirable image contents;
the video data processing device configured to identify indicators in a situation or scene recorded in the first video data that increase the likelihood of undesirable image contents to be contained in said first video data in the future based on recognized motions and gestures and set an alert state for the at least one sensor device in which a scanning rate for the at least one sensor device is increased and/or a scanning resolution of the at least one sensor device is increased in response to detection of the indicators.

US Pat. No. 10,368,128

MEMORY ALLOCATION TYPE FOR MEDIA BUFFER

Microsoft Technology Lice...

1. A computer device, comprising:a memory to store data and instructions;
a processor in communication with the memory;
an operating system in communication with the memory and the processor, wherein the operating system is operable to:
receive a plurality of camera resource requests from a plurality of applications to use a camera resource;
determine a memory type to allocate to the plurality of applications for the camera resource in response to the plurality of camera resource requests and compatibility information of the camera resource;
determine a buffer and a buffer type to provide each of the plurality of applications in response to an access mode of the camera resource, wherein the buffer type comprises one or more of a shared type, a copy type, or a secure type; and
provide each of the plurality of applications access to a respective determined buffer.

US Pat. No. 10,368,127

METHODS AND APPARATUS TO IDENTIFY AND CREDIT MEDIA USING RATIOS OF MEDIA CHARACTERISTICS

The Nielsen Company (US),...

1. An apparatus to identify media, comprising:a delta calculator to:
determine a first ratio based on a first time interval and a second time interval of a monitored media signal; and
determine a second ratio based on the second time interval and a third time interval of the monitored media signal; and
a signature generator to:
generate a monitored media ratio signature based on the first and second ratios; and
initiate transmission of the monitored media ratio signature to a recipient that is to compare the monitored media ratio signature with a reference ratio signature to identify the media;
at least one of the delta calculator or the signal generator implemented by at least one of a processor or hardware.

US Pat. No. 10,368,126

METHOD AND SYSTEM FOR DISPLAYING CONTENT OR CONFLICTS FROM MULTIPLE RECEIVING DEVICES ON A SECOND SCREEN DEVICE

The DIRECTV Group, Inc., ...

1. A method comprising:wirelessly requesting, at a second screen device, scheduled recording data from a set top box;
receiving, at the second screen device, scheduled recording data from the set top box at the second screen device, said scheduled recording data comprising a plurality of scheduled recording events;
displaying the scheduled recording events on a calendar screen display that simultaneously displays at least three consecutive days, each day having a plurality of timeslots, said scheduled recording events displayed in multiple timeslots for the at least three days;
determining conflicting scheduled recording events between at least two scheduled recording events based on the scheduled recording data;
displaying a screen indicator at the second screen device indicative of the conflict by displaying at least one of changing a color of a font of the conflicting scheduled recording events, underlining the conflicting scheduled recording events, placing a box around the conflicting scheduled recording events, and placing an indicator next to the conflicting scheduled recording events; and
selecting the screen indicator to initiate removing the conflict.

US Pat. No. 10,368,120

AVATAR INTEGRATED SHARED MEDIA EXPERIENCE

MICROSOFT TECHNOLOGY LICE...

1. A method for facilitating shared media consumption among two or more users associated with respective computing devices communicatively coupled via a network, the method comprising:receiving data indicative of two or more users associated with respective computing devices;
receiving a selection of a media content item to be concurrently rendered on the respective computing devices;
sending, to the respective computing devices of the two or more users, data of the media content item selected;
allowing an identified remote holder of the two or more users to send information pertaining to content playback of the media content item selected, the information comprising playback status, identification of the media content item, and a current time code associated with the media content item;
based on the information, allowing control of content playback on the respective computing devices of other users of the two or more users based at least in part on differences in the information pertaining to the content playback between the respective computing devices;
receiving a request from another user other than the identified remote holder requesting for remote holder status;
in response to receiving the request, allowing the identified remote holder to select to retain the remote holder status or transfer the remote holder status to the other user; and
when the identified remote holder selects to transfer the remote holder status, then facilitating the transfer of the remote holder status to the other user to allow the other user to obtain the control of the content playback.

US Pat. No. 10,368,119

METHOD, DEVICE AND COMPUTER PROGRAM PRODUCT FOR OUTPUTTING A TRANSPORT STREAM

Sony Corporation, Tokyo ...

1. A method of controlling video and/or audio stream playback, comprising:detecting a control input to a touch sensitive screen of a portable computing device; and
responsive to said detecting the control input to the touch sensitive screen, transitioning from outputting to the touch sensitive screen of the portable computing device a first stream of video and/or audio data provided by a first source to outputting to a second display device a second stream of video and/or audio data provided by a second source,
wherein content of the first stream of video and/or audio data is the same as content of the second stream of video and/or audio data, and
wherein the second source is different from the portable computing device.

US Pat. No. 10,368,118

SYSTEM AND APPARATUS FOR MANAGING VIDEO CONTENT RECORDINGS

1. A computing device, comprising:a processing system including a processor; and
a memory resource that stores executable instructions that, when executed by the processing system, facilitate performance of operations, comprising:
detecting a utilization of the memory resource that exceeds a threshold, wherein the threshold is less than a capacity of the memory resource;
obtaining a video recording schedule for the computing device;
determining a viewing threshold;
identifying a most recent viewing time for each video recording listed in the video recording schedule resulting in a group of most recent viewing times;
identifying a video recording from the video recording schedule that does not satisfy the viewing threshold based on a most recent viewing for the video recording resulting in an identified video recording;
identifying a mitigation option for the identified video recording to mitigate the utilization of the memory resource, wherein the mitigation option includes a change in the video recording schedule identifying candidate scheduled recordings based on a frequency of presentation of scheduled recordings;
generating a notice describing the utilization of the memory resource responsive to the detecting of the utilization of the memory resource exceeding the threshold, wherein the notice includes the mitigation option;
transmitting the notice over a wireless network to a portable communication device, wherein the notice is not provided to any device with a wired connection to the computing device; and
receiving a response message from the portable communication device that includes instructions to manage the memory resource of the computing device.

US Pat. No. 10,368,116

ROLL-OFF PARAMETER DETERMINING METHOD AND MODULE

MSTAR SEMICONDUCTOR, INC....

1. A roll-off parameter determining device, disposed at a receiving terminal, the receiving terminal comprising an analyzing module, the analyzing module analyzing a first frame and a second frame to identify first roll-off information in the first frame and second roll-off information in the second frame, the first frame being adjacent to the second frame, the roll-off parameter determining device comprising:a register unit, storing the first roll-off information;
a first determining unit, determining whether one of the first roll-off information and the second roll-off information comprises a first data type according to the first roll-off information received from the register unit and the second roll-off information received from the analyzing module to generate a first roll-off parameter indicator;
a second determining unit, determining whether at least one of the first roll-off information and the second roll-off information comprises a second data type according to the first roll-off information received from the register unit and the second roll-off information received from the analyzing module to generate a second roll-off parameter indicator; and
a look-up table (LUT) unit, looking up an LUT according to the first roll-off parameter indicator and the second roll-off parameter indicator to output a roll-off parameter.

US Pat. No. 10,368,107

INTRA VIDEO CODING USING A DECOUPLED TREE STRUCTURE

QUALCOMM Incorporated, S...

1. A method of coding video data, the method comprising:forming a most probable mode (MPM) candidate list for a chroma block of the video data, at least in part by:
adding, to the MPM candidate list, one or more derived modes (DMs) associated with a luma block of the video data, the luma block corresponding to the chroma block, and a plurality of luma prediction modes that can be used for coding luminance components of the video data;
adding one or more linear model (LM) modes to the MPM candidate list;
determining whether the one or more LM modes comprise a first instance of a first LM mode and one or more additional instances of the first LM mode; and
omitting the one or more additional instances of the LM mode from the MPM candidate list in response to a determination that the first LM mode was used to predict one or more neighboring chroma blocks of the chroma block;
selecting a mode from the MPM candidate list; and
coding the chroma block according to the mode selected from the MPM candidate list.

US Pat. No. 10,368,104

SYSTEMS AND METHODS FOR TRANSMISSION OF SYNCHRONIZED PHYSICAL AND VISIBLE IMAGES FOR THREE DIMENSIONAL DISPLAY

Rockwell Collins, Inc., ...

1. A method, comprising:obtaining physical data and visual data of at least one portion of an object, the physical data comprising vector quantized data in the form of hidden Markov model derived vectors;
encoding the physical data into a sequence of object frames, wherein each object frame represents a set of time-specific physical attributes of the at least one portion of the object;
encoding the visual data into a sequence of image frames, wherein each image frame represents a time-specific visual representation of the at least one portion of the object;
synchronizing and interlacing the sequence of object frames and the sequence of image frames to produce an interlaced data stream;
transmitting the interlaced data stream via a communication channel to a display device;
decoding the interlaced data stream by bypassing every object frame in the interlaced data stream to produce a visual data stream;
decoding the interlaced data by bypassing every image frame in the interlaced data stream to produce a physical data stream;
configuring the display device according to the decoded physical data to form a three-dimensional surface by deflecting each pin in an electro-mechanical pin field to a z-depth defined by the physical data; and
presenting the decoded visual data on the three-dimensional surface.

US Pat. No. 10,368,102

METHOD AND APPARATUS FOR IMAGE ENCODING/DECODING

1. A method of decoding an image, comprising:generating a prediction block for a current block;
receiving information of a block size, wherein the information of the block size is determined by an encoder, and wherein whether a skip of a transform process is applicable is determined based on a comparison of the information of the block size with a current block size;
decoding information indicating whether the skip of the transform process is applied, in response to the comparison of the information of the block size with the current block size representing that the skip of the transform process is applicable;
determining whether to perform an inverse transform on the current block based on the decoded information indicating whether the skip of the transform process is applied;
performing the inverse transform on the current block to generate a residual block for the current block; and
reconstructing the current block based on the prediction block and the residual block,
wherein the prediction block is generated by performing intra prediction.

US Pat. No. 10,368,101

METHOD AND APPARATUS FOR IMAGE ENCODING/DECODING

1. A method of decoding an image, comprising:generating a prediction block for a current block;
receiving information of a block size, wherein the information of the block size is determined by an encoder, and wherein whether a skip of a transform process is applicable is determined based on a comparison of the information of the block size with a current block size;
decoding information indicating whether the skip of the transform process is applied, in response to the comparison of the information of the block size with the current block size representing that the skip of the transform process is applicable;
determining whether to perform an inverse transform on the current block based on the decoded information indicating whether the skip of the transform process is applied;
performing the inverse transform on the current block to generate a residual block for the current block; and
reconstructing the current block based on the prediction block and the residual block.

US Pat. No. 10,368,099

COLOR REMAPPING INFORMATION SEI MESSAGE SIGNALING FOR DISPLAY ADAPTATION

Qualcomm Incorporated, S...

1. A method of processing decoded video data, the method comprising:determining, by a video decoding unit, a peak brightness value of a current display;
obtaining, by the video decoding unit and for a picture of video data, one or more colour remapping information (CRI) supplemental enhancement information (SEI) messages that each correspond to a respective peak brightness value of a set of peak brightness values, wherein each respective CRI SEI message of the CRI SEI messages includes a respective colour_remap_id syntax element that indicates the respective peak brightness value;
determining, for each respective CRI SEI message of the CRI SEI messages, the respective peak brightness value based on a value of the respective colour_remap_id syntax element included in the respective CRI SEI message;
selecting, by the video decoding unit and based on the peak brightness value of the current display, a CRI SEI message of the one or more CRI SEI messages;
colour remapping, by the video decoding unit and based on the selected CRI SEI message, samples of the picture of video data; and
outputting, by the video decoding unit and for display at the current display, the colour remapped samples of the picture of video data.

US Pat. No. 10,368,093

LINE-BASED COMPRESSION FOR DIGITAL IMAGE DATA

TEXAS INSTRUMENTS INCORPO...

1. A method of compressing digital image data comprising:computing a minimum absolute sample difference (MASD) for a pixel in a line of pixels based on neighboring pixels, wherein the neighboring pixels comprise a left neighboring pixel in the line of pixels, a top left neighboring pixel in a previous line of pixels, and a top neighboring pixel in the previous line of pixels, and wherein computing the MASD comprises computing an absolute sample difference (ASD) between the top left neighboring pixel and the top neighboring pixel, an ASD between the top left neighboring pixel and the left neighboring pixel, and an ASD between the top left neighboring pixel and an interpolated pixel value computed from the top neighboring pixel and the left neighboring pixel;
computing a pixel predictor and a pixel residual for the pixel based on the MASD; and
selectively encoding the pixel residual using one of an entropy code or run mode encoding.

US Pat. No. 10,368,090

INTRA-PREDICTION METHOD, AND ENCODER AND DECODER USING SAME

LG Electronics Inc., Seo...

1. A method for intra-prediction, performed by a decoding apparatus, the method comprising:receiving prediction mode information;
deriving an intra prediction mode for a current block based on the prediction mode information; and
generating a predicted block which includes prediction samples by deriving a prediction sample in the current block based on the intra prediction mode,
wherein when the intra prediction mode is a vertical prediction mode having a vertical prediction direction:
the prediction sample in the current block is derived by using a first reference sample located along the vertical prediction direction with regard to a location of the prediction sample, and
the step of generating the predicted block further includes filtering on the prediction sample when the prediction sample is adjacent to a left boundary of the current block,
wherein the filtering on the prediction sample is performed based on a second reference sample located along a horizontal direction with regard to the location of the prediction sample,
wherein the second reference sample is adjacent to a left side of the prediction sample, and
wherein for the filtering, a filtering coefficient applied to a value of the prediction sample is larger than a filtering coefficient applied to a value of the second reference sample.

US Pat. No. 10,368,089

VIDEO ENCODING METHOD AND APPARATUS, AND VIDEO DECODING METHOD AND APPARATUS

SAMSUNG ELECTRONICS CO., ...

1. A method of encoding a multilayer video, the method comprising:performing inter-layer prediction on a picture of each layer in the multilayer video;
determining a reference layer which the picture of the each layer refers to based on a result of performing the inter-layer prediction; and
adding reference layer information of each layer to a parameter set including information commonly applied to layers in the multilayer video,
wherein the reference layer information is added to at least one of a video parameter set (VPS), a sequence parameter set (SPS), and a picture parameter set (PPS),
wherein the reference layer information includes a flag layer_dependency_present_flag indicating whether a current layer is a dependent layer including a picture predicted by referring to other picture included in other layer or is an independent layer without referring to the other picture included in the other layer, and
when the flag layer_dependency_present_flag indicates that the current layer is the dependent layer, the reference layer information further includes a flag direct_reference_flag[i][j] indicating whether the current layer i having an index i refers to a layer j having a different index j, where i and j are integers, and
when the flag layer_dependency_present_flag indicates that the current layer is the independent layer, the flag direct_reference_flag[i][j] for the current layer is not obtained from the bitstream.

US Pat. No. 10,368,084

VIDEO SIGNAL PROCESSING METHOD AND DEVICE

KT CORPORATION, Gyeonggi...

1. A method of decoding a video signal, the method comprising:generating a reference picture list based on a current picture reference flag for a current picture;
obtaining motion information about a current block in the current picture, the motion information including at least one of a motion vector and a reference picture index; and
restoring the current block using the motion information of the current block and the reference picture list relating to the current picture,
wherein the current picture reference flag indicates whether at least one block belonging to the current picture is predicted by referring to a pre-reconstructed block in the current picture, and
wherein the current picture is added to the reference picture list when the current picture reference flag indicates that at least one block belonging to the current picture is predicted by referring to a pre-reconstructed block in the current picture.