US Pat. No. 10,166,521

PROCESS AND SYSTEM FOR CONVERSION OF CARBON DIOXIDE TO CARBON MONIXIDE

CCP Technology GmbH, (DE...

1. An apparatus for converting carbon dioxide CO2 into carbon monoxide CO comprising:a hydrocarbon converter for decomposing a hydrocarbon containing fluid into carbon and hydrogen, wherein the hydrocarbon converter comprises at least one process chamber having at least one inlet for a hydrocarbon containing fluid and at least one outlet for carbon and hydrogen, and wherein the hydrocarbon converter comprises at least one unit for introducing energy into the process chamber, the energy consisting at least partially of heat, wherein the at least one unit for introducing energy into the process chamber is designed in such a way that it can generate, at least locally, temperatures above 1000° C.;
a CO2 converter for converting CO2 into CO, the CO2 converter comprising at least one further process chamber having at least one inlet for CO2 adapted to introduce CO2 from an external CO2 source into the CO2 converter, at least one inlet for carbon and hydrogen, and at least one outlet, wherein the inlet for carbon and hydrogen is directly connected to the at least one outlet of the hydrocarbon converter.

US Pat. No. 10,166,511

METHOD FOR THE PRODUCTION OF A HOLLOW FIBER MODULE, AND HOLLOW FIBER MODULE

Sartorius Stedim Biotech ...

1. A method for producing a hollow fiber module (1, 1?), comprising:inserting a hollow fiber bundle (3) into a module housing (2, 2?) that has an end closed by a cap (17) that defines a removable sprue cover (18, 18?, 18?);
filling a fluid first component (27) via a first inflow (26) and into an intermediate space arranged between the hollow fiber ends (6, 7) and the cap (17) to form a spacer, the fluid first component (27) being formed from a material that can assume a solid state and being filled so that the hollow fiber ends (6, 7) project into the first component (27);
introducing a fluid curable second component (4) upstream of the first component (27), directed away from the cap (17), via a second inflow (28);
curing the second component (4) to form a sealing layer (9) that embeds the hollow fiber bundle (3) and seals the hollow fiber bundle (3) with respect to an adjacent module housing wall (29, 29?);
applying a rotary pulling movement to the cap (17) and thereby severing the hollow fibers (5) in a boundary layer formed by the first component (27) and the second component (4); and
removing from the module housing (2, 2?) an assembly that includes: the cap (17), the first component (27) that has been solidified to form a plug (30), and the hollow fiber ends (6) embedded in the plug (30) and projecting out of the end face (10) of the layer (9) formed by the second component (4).

US Pat. No. 10,166,507

PROCESS FOR HYDROCHLORIC ACID MEDIATION

Fuel Tech, Inc., Warrenv...

1. A process for reducing the chloride content in a gas stream to reduce the amount of chlorides in it, comprising: introducing a copper bearing chloride remediator composition in aqueous form into contact with combustion gases within a defined introduction zone under conditions effective for HCl emissions control; and passing the gases from the introduction zone to a particulate recovery device to provide a reduced chloride gas stream.

US Pat. No. 10,166,503

WATER CONTROL IN NON-AQUEOUS ACID GAS RECOVERY SYSTEMS

Research Triangle Institu...

17. A process for regulating water content and removing acid gases from a water-containing gas stream using a non-aqueous solvent (NAS) absorption liquid, wherein the NAS absorption liquid has a solubility of less than about 10 g of water per 100 g of NAS which comprises:(a) treating the gas stream in an absorption zone with the NAS absorption liquid under a first set of controlled conditions of temperature, pressure and flow rate to obtain an acid gas-depleted treated gas stream and an acid gas-loaded NAS absorption liquid;
(b) directing the acid gas-loaded NAS absorption liquid to a regeneration zone under a second set of controlled conditions of temperature, pressure and flow rate and regenerating the loaded NAS absorption liquid to expel a portion of the acid gases and obtain a regenerated NAS absorption liquid;
(c) directing the regenerated NAS absorption liquid to step a); and
(d) controlling the first and second set of conditions such that the temperature for the first set of controlled conditions is greater than 30° C. and less than 57° C. so as to (i) balance the water content entering the process in the water-rich gas stream with the water content leaving the process and
(e) remove acid gases from the water-rich gas stream.

US Pat. No. 10,166,498

GAS-EVACUATING FILTER

Hayward Industries, Inc.,...

1. A filter for fluid systems, comprising:a vessel defining an inner chamber and having an inlet and an outlet in fluid communication with the inner chamber;
a filter cartridge positioned within the inner chamber of the vessel; and
a tubular assembly having an upper end including a tube inlet, a lower end, an inner cavity extending between the tube inlet and the lower end, an interlocking section for engaging a portion of the outlet, a flow path extending between the tube inlet to the outlet when the tubular assembly is engaged with the outlet, and a solid sidewall extending between the lower end and the upper end, the tubular assembly positioned within the filter cartridge and the inner chamber of the vessel so as to force at least a portion of fluid flowing through the filter to flow along the solid sidewall toward the upper end, through the tube inlet into the inner cavity, and through the tubular assembly flow path before exiting the outlet and forcing gas trapped in the vessel to be discharged from the vessel,
wherein the tubular assembly includes one or more apertures that permit at least a portion of fluid flowing through the filter to flow into the inner cavity of the tubular assembly through the one or more apertures and exit the outlet without first entering the tube inlet.

US Pat. No. 10,166,482

METHOD OF OPERATING SCREEN BASEBALL SYSTEM

REALYAGU ZONE CO., LTD., ...

1. A method of operating a screen baseball system, the method comprising:(a) registering a personal rank of a user by a computer;
(b) displaying a pitching motion on a screen and starting a pitching action according to a selected pitch type;
(c) performing a simulation along a trajectory of a batted ball, which is obtained by receiving and converting batting detection data of a batter among users, and displaying an image on the screen by the computer;
(d) photographing a batting image of the batter and storing the batting image in a database by a camera such that the batting image is utilized for a user training program and a character development program; and
(e) transmitting simulation information and batting image data, which are displayed, to a game shop, in which another user is positioned, in real time by a game server to play a game on line if the another user is positioned in a remote place,
wherein the method includes monitoring and controlling steps (a) to (e), and the step (b) comprises previously storing an adjustment value for a specific pitch into an embedded memory device of a pitching machine section by considering that each shop has a different revolution of pitching machine and a different distance between the pitching machine and a batter box.

US Pat. No. 10,166,471

SYSTEM, METHOD, AND GRAPHICAL USER INTERFACE FOR CONTROLLING AN APPLICATION ON A TABLET

Sony Interactive Entertai...

1. A method, comprising:communicating, by a client device, with a hosting service a selection of an online application;
receiving, by the client device, streaming video content from execution of the online application on a server of the hosting service, for rendering at a user interface of the client device;
receiving, by the client device, program code for a configuration of a virtual controller used for interacting with the streaming video content from the hosting service, the program code being specific for the online application, wherein the program code includes user specific adjustments to the configuration defined for the online application from a previous configuration session;
executing, by the client device, the program code of the virtual controller, the execution causing an interactive image of the virtual controller to be rendered at the user interface, the interactive image of the virtual controller identifying controls of the virtual controller that are specific for the client device;
receiving, by the client device, user input via the controls provided by the virtual controller to communicate functionality that parallels functionality of buttons of a physical game controller, the user input being interpreted based on the user specific adjustments, the user input provided to control aspects of the online application being executed by the server.

US Pat. No. 10,166,455

ADJUSTABLE PUTTING GREEN SYSTEM AND METHOD THEREOF

DERON, LLC, Providence, ...

1. A system for a person to practice putting, the system comprising:a framework;
a plurality of actuators coupled to the framework in an array, each actuator including guide structure, a motor and a shaft, the shaft vertically extending between the motor and an upper support, the upper support coupled to an end of the shaft such that the upper support maintains a fixed position relative to linear movement of the end of the shaft, the motor configured to linearly move the shaft and the upper support relative to the framework, the upper support having an upward facing surface, the guide structure configured to guide vertical and linear movement of both the motor and the shaft to move the upper support to various predetermined heights;
an artificial green having multiple layers and a putting surface with a cup defined in the putting surface, the artificial green positioned over the actuators, the upward facing surface of the upper support directly contacting an underside of the multiple layers of the artificial green below the putting surface;
a control system coupled to the actuators, the control system including multiple controllers configured to control actuation of the actuators; and
a computing device coupled to the control system and configured to communicate with the control system, the computing device coupled to a display and including user input controls.

US Pat. No. 10,166,450

DEVICE FOR ALLOWING SMALL CUPS TO TEMPORARILY SIT INSIDE LARGER BEER PONG CUPS

1. A device adapted for contacting with an uppermost rim of a smaller diameter cup and enabling the uppermost rim of the smaller diameter cup to sit parallel to and on a same horizontal plane as an uppermost rim of a larger diameter cup when both the smaller diameter cup and the larger diameter cup are used for a beer pong drinking game, said smaller diameter cup designed to hold a different beverage than the larger diameter cup, said device comprising:a continuous elastic band for: (i) clipping onto the uppermost rim of the smaller diameter cup and (ii) enabling the uppermost rim of the smaller diameter cup to rest substantially parallel to and on a same horizontal plane as the uppermost rim of the larger diameter cup when the smaller diameter cup is positioned inside the larger diameter cup for use during the beer pong drinking game in which the smaller diameter cup holds a different beverage than the larger diameter cup, said continuous elastic band having three or more spaced downward protrusions for at least temporarily clipping onto the uppermost rim of the smaller diameter cup when the smaller diameter cup and the larger diameter cup are used together in the beer pong drinking game.

US Pat. No. 10,166,436

METHODS AND PROGRAM PRODUCTS FOR BUILDING A WORKOUT

adidas AG, Herzogenaurac...

1. A method for generating a workout with a computing device comprising:the computing device receiving user input indicating features of a desired workout;
the computing device generating the workout, wherein the workout comprises a plurality of intervals, and wherein a first interval comprises an interval intensity and an interval duration
the computing device initiating a graphical display that conveys the number of intervals making up the workout and the interval intensity and the interval duration of the first interval; and
the computing device determining whether a user has performed above the interval intensity for a portion of the interval duration, and adjusting the interval intensity in response to the determination,
wherein the graphical display comprises a plurality of adjacent segments,
wherein each segment represents one of the plurality of intervals,
wherein receiving the user input indicating features of the desired workout comprises receiving at least three numerical inputs from the user: a first numerical input specifying a desired number of intervals, a second numerical input specifying a desired intensity of the first interval, and a third numerical input specifying a desired duration of the first interval,
wherein receiving the user input indicating features of the desired workout further comprises receiving feedback from direct user manipulation of at least one of the segments representing at least one of the plurality of intervals, and
wherein direct user manipulation comprises placing an object over a portion of the segment.

US Pat. No. 10,166,435

BACK EXTENSION EXERCISE APPARATUS

Cybex International, Inc....

1. An exercise apparatus for performing a back extension exercise by a user having a lower back, legs and a trunk that has a longitudinal trunk axis and a trunk weight, the apparatus comprising:a frame,
a seat having a seating surface and a pelvic stabilization pad having a lower back engagement surface,
an input arm assembly interconnected by a first interconnection to a first resistance mechanism,
the input arm assembly including a manually graspable mechanism and being arranged on the apparatus such that the input arm assembly is pivotable beginning from a start motionless position along a path of travel rearwardly toward the pelvic stabilization pad under resistance exerted by the first resistance mechanism,
the seating surface and the pelvic stabilization pad being mounted, adapted and arranged on the frame in a disposition such that the user can simultaneously sit on the seating surface, engage the user's lower back against the lower back engagement surface and manually engage the manually graspable mechanism to pull the input arm assembly against resistance exerted by the first resistance mechanism,
wherein the first resistance mechanism is adapted to increase resistance as a degree of pivoting of the input arm assembly increases along the path of travel away from the start motionless position rearwardly toward the pelvic stabilization pad,
wherein the input arm assembly is interconnected to the first resistance mechanism by a cable, the input arm assembly being interconnected to a cam having a receiving groove that receives the cable, the cam being interconnected to the input arm assembly such that the cam rotates together with pivoting of the input arm assembly, the receiving groove having a profile selected to create a lesser torque force against the user's pulling force when the user starts pulling the arm assembly from the start motionless position and gradually increase torque force against the user's pulling force as the user continues to pull the input arm assembly rearwardly, and wherein the apparatus includes a second interconnection to a second manually selectively adjustable fixed weight resistance mechanism.

US Pat. No. 10,166,428

ADJUSTABLE CLUB

1. An adjustable club comprising:an elongate handle, defined by a proximal end and a distal end, having an opening to a bore at the distal end;
a stud, having an end cap at a distal end of the stud and a rod at a proximal end of the stud configured to engage the bore of the elongate handle;
one or more weights having a centrally located bore extending between a first opening and a second opening, configured to accommodate the stud;
wherein each of the one or more weights has one or more dowels protruding from a proximal side and one or more receiving holes on a distal side, the one or more receiving holes configured to engage the one or more dowels protruding from another of the one or more weights, thereby preventing the one or more weights from rotating relative to one another;
wherein the distal end of the elongate handle has a frustoconical configuration and tapers outward in a distal direction;
wherein the elongate handle further comprises at least one receiving hole, configured to engage the one or more dowels of one of the one or more weights, thereby preventing the one or more weights from rotating relative to the elongate handle;
wherein a proximal end of the rod engages the centrally located bore the one or more weights and the bore of the elongate handle having a friction fit that prevents rotational movement;
wherein the bore of the elongate handle is a threaded bore and the rod of the stud is configured to engage the threaded bore having a frictional fit that prevents longitudinal and rotational movement; and
wherein the proximal end of the elongate handle is a counterweight with a weight equal to a weight of one of the one or more weights such that the center of gravity is down shifted by fifty percent along a longitudinal axis of the elongate handle.

US Pat. No. 10,166,422

TRAMPOLINE SUPPORT FRAME

CROWNTEC (JIANG XI) SPORT...

1. A trampoline support frame comprising a plurality of transversal branch pipes connected to each other so as to form an annular frame provided for a bouncing component to be mounted at inner side thereof, and a plurality of longitudinal branch pipes provided to one of said transversal branch pipes, characterized in that each of said longitudinal branch pipes is respectively provided with a fitting portion, two reinforcing portions integrally extended from said fitting portion to corresponding two side surfaces of said transversal branch pipe and then fixed to said transversal branch pipe by welding, an accommodating space formed between said two reinforcing portions and provided for one of said transversal branch pipes to be located therein, and two bearing surfaces, each of which is formed between two ends of said two reinforcing portions and toward said accommodating space so as to support one of said transversal branch pipes; wherein each of said transversal branch pipes is respectively provided with a curved portion, a first connecting portion provided at one end of said curved portion, and a second connecting portion provided at another end of said curved portion and covering while being fixed to said first connecting portion of another transversal branch pipe, and said first connecting portion is provided with a first opening, and said second connecting portion is provided with a second opening covering said first opening, each of said first connecting portion is respectively provided with two first stepped surfaces located at two opposite outer sides of said first opening while in parallel with each other, and each of said second connecting portions is respectively provided with two second stepped surfaces located at two opposite outer sides of said second opening while in parallel with said two first stepped surfaces, said two reinforcing portions of each of said longitudinal branch pipes being attached to said two second stepped surfaces by welding.

US Pat. No. 10,166,419

METHOD AND SYSTEM FOR DILUTING MULTIPLE CHEMICAL CONCENTRATES AND DISPERSING RESULTANT SOLUTIONS UTILIZING A SINGLE PORTABLE SOURCE

PERIMETER SOLUTIONS LP, ...

1. A system for diluting concentrated liquids and dispersing resultant solutions comprising:a plurality of concentrated liquid chemical containers;
a plurality of control valves each correspondingly connected to the plurality of concentrated liquid chemical containers and in fluid relationship therewith;
a single high pressure pump connected to each of the plurality of control valves and in fluid relationship therewith, wherein the plurality of control valves are connected between the plurality of concentrated liquid chemical containers and the single high pressure pump such that when the single high pressure pump is energized, the single high pressure pump solely draws the concentrated liquid chemicals from the plurality of liquid chemical containers through the corresponding control valves;
a liquid pressure adjustment valve connected to both the single high pressure pump and a source of diluent or solvent and in fluid relationship;
a hose connected to the liquid pressure adjustment valve and in fluid relationship; and
a nozzle connected to the hose and in fluid relationship for dispersing a diluted solution, wherein the hose is connected between the liquid pressure adjustment valve and the nozzle.

US Pat. No. 10,166,418

FIRE PROTECTION STRIP

HILTI AKTIENGESELLSCHAFT,...

1. A fire-protection tape, comprising:at least two main plies comprising an intumescent material, wherein the plies have a first longitudinal edge on one outer side and a second longitudinal edge on an opposite outer side, in each instance; and
at least one intermediate ply comprising a second intumescent material disposed between adjacent main plies;
wherein the second intumescent material has a lower intumescence temperature than the material of the main plies, and
wherein the intermediate ply is disposed at the first longitudinal edges of the main plies, wherein the second longitudinal edges of the main plies are flexibly connected with one another, such that the main plies are configured to gape apart at the first longitudinal edges after activation of the intermediate ply, and wherein the intermediate ply does not extend to the second longitudinal edges of the main plies.

US Pat. No. 10,166,406

RADIATION TREATMENT PLANNING AND DELIVERY USING COLLISION FREE REGIONS

Varian Medical Systems In...

1. A method of determining a radiation treatment plan for delivering radiation to a patient using an external-beam radiation treatment system, the method comprising:receiving, by a computer system, one or more class solutions, wherein each class solution includes field geometry limits for one or more treatment axes of the external-beam radiation treatment system and a corresponding collision free region, and wherein the collision free region comprises a three-dimensional space for allowed initial isocenter positions determined based on a delivery machine model and a patient model;
receiving, by the computer system, a three-dimensional image of the patient;
aligning the three-dimensional image of the patient with the collision free regions of the one or more class solutions;
receiving, via a user interface, a desired initial isocenter position;
determining, by the computer system, that the desired initial isocenter position is within at least one collision free region of the one or more class solutions;
identifying, by the computer system, one or more treatment fields within the field geometry limits of a class solution corresponding to the at least one collision free region; and
determining, by the computer system, the radiation treatment plan using the one or more identified treatment fields.

US Pat. No. 10,166,404

METHOD FOR IRRADIATION PLANNING

GSI Helmholtzzentrum fur ...

15. Control device for a radiation facility that provides a scanned particle beam, havinga control unit that controls the radiation facility during irradiation in order to approach target points of a target volume located in a body with the scanned particle beam,
wherein an irradiation plan is divided into a plurality of temporally consecutive irradiation sub-plans including a first irradiation sub-plan and a second irradiation sub-plan, wherein the target points of the target volume are divided among the irradiation sub-plans into a plurality of subsets of target points including a first subset of target points of the first irradiation sub-plan and a second subset of target points of the second irradiation sub-plan wherein the second subset of target points is different from the first subset of target points, and wherein the subsets are each distributed over the entire target volume, and
wherein mutually adjacent target points are assigned to different subsets, such that approach of the target points is varied from irradiation sub-plan to irradiation sub-plan.

US Pat. No. 10,166,398

METHODS AND APPARATUS FOR MANAGING MULTIPLE CATHODE PACING

Cardiac Pacemakers, Inc.,...

1. An apparatus for electrical coupling to a plurality of implantable electrodes, the apparatus comprising:a stimulus circuit configured to deliver electrical pacing stimulation to the plurality of implantable electrodes;
a switch circuit configured to electrically couple different combinations of the plurality of implantable electrodes to the stimulus circuit; and
a control circuit to configure a stimulation vector that includes a first electrode of the plurality of implantable electrodes as a first vector electrode and multiple other electrodes of the plurality of implantable electrodes electrically coupled together to form a second combined vector electrode, wherein the control circuit includes a capture detection sub-circuit configured to determine individual capture stimulation energy level thresholds between the first vector electrode and each single electrode of the combined vector electrode; and wherein the control circuit is configured to determine a capture stimulation energy level threshold of the stimulation vector using the determined individual capture thresholds.

US Pat. No. 10,166,396

EFFICIENT DELIVERY OF MULTI-SITE PACING

Medtronic, Inc., Minneap...

1. A pacing device comprising a set of electrodes including a first ventricular electrode and a second ventricular electrode, spatially separated from one another and all coupled to an implantable pulse generator, the device comprising:a processor configured for selecting a first cathode and a first anode from the set of electrodes to form a first pacing vector at a first pacing site along a heart chamber and selecting a second cathode and a second anode from the set of electrodes to form a second pacing vector at a second pacing site along the same heart chamber;
the pulse generator configured to deliver first pacing pulses to the first pacing vector and delivering second pacing pulses to the second pacing vector;
the pulse generator for generating a recharging current for recharging a first coupling capacitor over a first recharge time period in response to the first pacing pulses;
the pulse generator for generating a recharging current for recharging a second coupling capacitor over a second recharge time period in response to the second pacing pulses; and
wherein an order of recharging the first and second coupling capacitors is dependent upon ventricular pacing mode, left ventricle to right ventricle delay, (V-V) pace delay, multiple point LV delay, and latest delivered pacing pulses to one of the first and second pacing vectors.

US Pat. No. 10,166,388

METHOD FOR EXTRACTING TEMPORAL FEATURES FROM SPIKE-LIKE SIGNALS

MED-EL Elektromedizinisch...

1. A system for cochlear implant signal processing, the system comprising:a cochlear implant signal processor configured to convert a speech signal input into multi-channel stimulation pulse sequences for a cochlear implant electrode array;
a temporal feature processing module configured to extract temporal feature information based on fine structure information from the stimulation pulse sequences; and
a speech recognition engine configured to evaluate the temporal feature information using automatic speech recognition to produce speech recognition outputs corresponding to the speech signal input.

US Pat. No. 10,166,366

COMPACT URINARY CATHETERS AND METHODS FOR MAKING THE SAME

HOLLISTER INCORPORATED, ...

1. A catheter sub-assembly comprising:a gripping member and a catheter tube carried by and attached to said gripping member, said catheter sub-assembly having a central longitudinal axis,
said catheter tube having a proximal end and a distal end and defining a flow path between said distal and proximal ends wherein said catheter tube is angularly adjustable relative to said axis; and
said gripping member including an outer gripping surface and an aperture in said outer gripping surface in liquid flow communication with said flow path of said catheter tube wherein said gripping member is configured for retaining said catheter tube in an angularly adjusted position relative to said axis.

US Pat. No. 10,166,364

SYSTEMS AND METHODS FOR IMPROVING CATHETER HOLE ARRAY EFFICIENCY

Becton, Dickinson and Com...

1. A peripheral catheter, comprising:a tubular body member of a predetermined diameter and having a wall thickness, the tubular body member having a proximal end, a distal end and a lumen extending therebetween, the tubular body member further having a truncated length sufficient to access a peripheral vein of a patient, the distal end comprising a tapered tip;
a first stripe of a stiffening material;
a second stripe of the stiffening material;
a third stripe of the stiffening material, wherein each of the first stripe, the second stripe and the third stripe are generally aligned with a longitudinal axis of the tubular body member and embedded within the wall thickness of the tubular body member; and
a plurality of holes comprising a first hole disposed between the first stripe and the second stripe and at least partially disposed on the tapered tip of the tubular body member, the plurality of holes further comprising a second hole disposed between the second stripe and the third stripe and at least partially disposed on the tapered tip of the tubular body member, the first hole and the second hole being formed through the wall thickness of the tubular body member and in communication with the lumen.

US Pat. No. 10,166,363

CATHETER

ASAHI INTECC CO., LTD., ...

1. A catheter comprising:a tube body including an inner layer, a reinforcing body covering the inner layer, and an outer layer covering the reinforcing body;
a tubular metallic distal end tip provided at a distal end of the tube body;
a slit on the distal end tip; and
an outer coating on an outer peripheral surface of the distal end tip, at least part of the outer coating is disposed within the slit,
wherein:
the distal end tip has a tapered portion so that a diameter of the distal end tip decreases toward a distal end of the distal end tip, and
a depth of the slit gradually reduces towards the distal end of the distal end tip.

US Pat. No. 10,166,362

PULMONARY EMBOLISM APPARATUS

Sanford Health, Sioux Fa...

1. An apparatus comprising:a first catheter having a proximal end and a distal end, wherein a distal portion of the first catheter includes a first plurality of outlets, and wherein the first catheter has an opening arranged between the proximal end of the first catheter and the first plurality of outlets;
a first tubular housing having a proximal end and a distal end, wherein an exterior surface of the first tubular housing is coupled to an exterior surface of the first catheter proximal to the first plurality of outlets;
one or more pressure sensors coupled to the distal end of the first tubular housing;
a second catheter having a proximal end and a distal end, wherein a distal portion of the second catheter includes a second plurality of outlets, and wherein the distal end of the second catheter is configured to be positioned substantially within the first catheter when the second catheter is in a first position, and wherein the distal end of the second catheter is configured to extend through the opening in the first catheter in a second position; and
a catheter diverter coupled to an interior surface of the first catheter and projecting inward from the opening of the first catheter towards the proximal end of the first catheter to partially obstruct a lumen of the first catheter, such that the second catheter is configured to contact the catheter diverter and is thereby directed through the opening of the first catheter as the second catheter moves from the first position to the second position.

US Pat. No. 10,166,358

MASK ASSEMBLY SUPPORTING ARRANGEMENTS

ResMed Limited, Bella Vi...

1. A headgear assembly for supporting a patient interface for treating a wearer having a breathing disorder with gas pressurized above atmospheric pressure, the headgear assembly comprising:first and second joining portions configured to be arranged on and removably attachable to opposite ends of the patient interface, each of the first and second joining portions having a patient interface attachment portion at a first end configured to attach to the patient interface, and a headgear attachment portion at a second end; and
headgear having a first strap assembly and a second strap assembly, each of the first and second strap assemblies having:
a first strap portion including:
a first end that is removably attachable to the headgear attachment portion of the respective joining portion; and
a second end that is attached to an ear interface assembly; and
a second strap portion including:
a first end that is removably attachable to the headgear attachment portion of the respective joining portion; and
a second end that is attached to the ear interface assembly; and
the ear interface assembly being structured and dimensioned to be secured to the wearer's ear in use.

US Pat. No. 10,166,357

DELIVERY OF RESPIRATORY THERAPY WITH NASAL INTERFACE

RESMED LIMITED, Bella Vi...

1. A respiratory mask for continuous positive airway pressure treatment comprising:a cushion adapted to be positioned against the face of a patient to deliver breathable gas to the patient,
the cushion being constructed from a polyurethane foam and being configured to form a gasket sealing arrangement around an entrance to the airways of the patient, the cushion including only one exit orifice formed therein to expel the breathable gas from the cushion to deliver the breathable gas to the patient's airways, the exit orifice being configured to be positioned externally of the patient's airways and in fluid communication therewith,
the cushion having a main body and two wings integral with the main body and extending respectively from opposite lateral sides of the main body,
wherein the cushion comprises a single continuous sealing surface extending across the main body, at least a portion of the sealing surface being arranged to, in use, seal with the underside of the patient's nose, the sealing surface having a saddle shape with curvature in two directions including a first direction and a second direction, the first direction being transverse to the second direction,
wherein the curvature in the first direction forms a concave shape, and the curvature in the second direction forms a convex shape structured to accommodate the naso-labial angle of a patient's nose.

US Pat. No. 10,166,356

REVERSIBLE FRAME FOR A PATIENT INTERFACE ASSEMBLY

KONINKLIJKE PHILIPS N.V.,...

1. A method of using a patient interface assembly including a patient interface device and a support assembly, the patient interface device includes a cushion assembly having a support assembly coupling, the support assembly including at least one strap and a reversible frame assembly, the reversible frame assembly including a frame assembly body having a first side and a second side, the frame assembly body including at least a first substantially flat, elongated member and a second substantially flat elongated member, a cushion assembly coupling, and a reversing device, each of the first body member and the second body member coupled at a proximal end to the cushion assembly coupling, the frame assembly body structured to be coupled to the cushion assembly at the cushion assembly coupling with the cushion assembly substantially disposed on one of the first or second sides of the frame assembly body, the frame assembly body structured to be disposed in one of two concave configurations, a first concave configuration, wherein the body first side is concave about at least a portion of the cushion assembly, and a second concave configuration, wherein the body second side is concave about at least a portion of the cushion assembly, and the reversing device structured to allow the frame assembly body to move between the first configuration and second configuration, the method comprising the steps of:coupling the cushion assembly to the frame assembly body while the frame assembly body is in the first configuration;
decoupling the cushion assembly from the frame assembly body;
placing the frame assembly body in the second configuration; and
coupling the cushion assembly to the frame assembly body while the frame assembly body is in the second configuration.

US Pat. No. 10,166,355

NASAL MASK SYSTEM

ResMed Limited, Bella Vi...

1. A nasal mask for delivery of a supply of air to an entrance of a patient's airways, the nasal mask comprising:a superior sealing portion and an inferior sealing portion,
wherein the superior sealing portion and the inferior sealing portion provide a sealing region including a flexible membrane adapted to engage a patient's face and form a seal around both nares of a patient's nose,
wherein the superior sealing portion is constructed and arranged to be substantially located on and to form a seal with a portion of the cartilaginous framework of a patient's nose,
wherein the superior sealing portion comprises the flexible membrane without an undercushion or backup band to provide a first sealing mechanism,
wherein the inferior sealing portion is constructed and arranged to be located in part on a portion of an upper lip of a patient and to direct a sealing force to a portion of a maxilla bone of the patient,
wherein the inferior sealing portion comprises the flexible membrane and an undercushion or backup band to provide a second sealing mechanism that is different than the first sealing mechanism, and
wherein the first and second sealing mechanisms are configured and arranged around a perimeter of the sealing region such that a contact area of the sealing region engaged with the patient's face in use varies around the perimeter of the sealing region to form the seal around both nares of the patient's nose.

US Pat. No. 10,166,346

BRUISELESS CANNULA

Q-MED AB, Uppsala (SE)

1. A needle device configured for an injection apparatus, wherein said needle device comprises:a housing configured to be mounted to an injector, said housing comprising a first housing element provided towards a proximal end of said needle device and a second housing element provided towards a distal end of said needle device;
a cutting element arranged at a proximal end of said first housing element, said cutting element having a sharp proximal end;
a cannula fitted to the second housing element, said cannula having a blunt proximal end; and
an opening for said cannula provided at the proximal end of the first housing element,
wherein the first housing element and the second housing element are moveable relative to each other between an extended position and a compressed position,
wherein the proximal end of the cannula does not extend beyond the proximal end of the cutting element when the first and second housing elements are in the extended position,
wherein the cannula extends through the opening of the first housing element and past the proximal end of the cutting element when the first and second housing elements are in the compressed position, and
wherein the first housing element is provided within the second housing element, and a resilient member is provided within the housing and biases the first housing element and the second housing element in a direction from the compressed position towards the extended position.

US Pat. No. 10,166,344

INJECTION NEEDLE ASSEMBLY

SHL GROUP AB, Nacka Stra...

1. An injection needle assembly having opposite distal and proximal ends, comprising:(a) a tubular needle cover comprising,
an open distal end having an inner diameter;
an inner circumferential surface having,
a plurality of axially extending ledges; and
a first thread having a first pitch in a first direction;
(b) a tubular needle holder comprising,
an injection needle; and
an outer circumferential surface having two separate engagement devices, the first engagement device comprising cut-outs configured to engage the axially extending ledges of the needle cover and the second engagement device comprising a second thread having a second pitch in a second direction; and
(c) a tubular cap comprising,
an outer circumferential surface having a third thread that engages the first thread of the needle cover, a central passage having a diameter larger than the outer circumferential surface of the tubular needle holder and a fourth thread configured to engage the second thread of the needle holder, wherein the third thread is configured to threadedly engage a proximal end of a container attachment device that operatively connects to a proximal end of a medicament container,
wherein the inner diameter of the open distal end of the needle cover completely encloses the needle holder and the cap, where a protective cover seals the open distal end to maintain sterility of the needle.

US Pat. No. 10,166,337

HAND-ACTUATED SYRINGE WITH VACUUM CHAMBER FOR AUTO REFILL

LIEBEL-FLARSHEIM COMPANY ...

1. A method for operating a fluid delivery system that is separate from but connectable to a patient, said fluid delivery system comprising a syringe and a separate fluid source, said syringe comprising a syringe body, a plunger comprising a plunger head disposed within said syringe body, a vacuum chamber within said syringe body, a discharge chamber within said syringe body, a fill port to said discharge chamber, and a discharge port from said discharge chamber, wherein said plunger head is disposed between and separates said discharge chamber from said vacuum chamber such that said discharge chamber and said vacuum chamber are disposed on opposite sides of said plunger head within said syringe body, and wherein said plunger head fluidly isolates said vacuum chamber from said discharge chamber, said method comprising:executing a first moving step comprising moving said plunger and said plunger head relative to said syringe body and in a discharge direction to discharge a gaseous fluid from said discharge chamber, while said discharge port is disconnected from said patient, and by said plunger head interfacing with said gaseous fluid within said discharge chamber;
creating a vacuum within said vacuum chamber, wherein said vacuum within said vacuum chamber biases said plunger and said plunger head in a retraction direction that is opposite of said discharge direction, and wherein said creating a vacuum step results from said first moving step;
exerting a separate biasing force on said plunger that also biases said plunger and said plunger head in said retraction direction;
executing second moving step after said first moving step, said second moving step comprising moving said plunger and said plunger head relative to said syringe body in said retraction direction using each of said vacuum within said vacuum chamber and said separate biasing force, wherein said vacuum within said vacuum chamber and said separate biasing force exert separate forces on said plunger that each tend to move said plunger and said plunger head in said retraction direction;
drawing fluid into said discharge chamber from said fluid source and through said fill port using said second moving step;
fluidly connecting said discharge port with said patient; and
executing a third moving step after said drawing step, said third moving step comprising moving said plunger and said plunger head relative to said syringe body said discharge direction and with said plunger head interfacing with said fluid within said discharge chamber, all to discharge said fluid from said discharge chamber through said discharge port and to then inject said fluid into said patient.

US Pat. No. 10,166,333

METHOD FOR GENERATING A MONITORING SIGNAL USING A SUPERVISING ENTITY OR SAFETY MODULE

Roche Diabetes Care, Inc....

1. A method for generating a monitoring signal by monitoring laboratory values of a patient using a medical app, the medical app being executed on a mobile device of the patient, wherein the execution of the medical app on the mobile device of the patient is supervised by a supervising entity or safety module, the supervising entity or safety module comprising at least executable program instructions, the medical app comprising executable instructions for executing at least one sequence of processes for generating the monitoring signal, the processes comprising safety critical processes, the sequence of processes being triggered by the measurement of the laboratory values, such as the blood glucose level of the patient, the method comprising:executing a first process of the sequence of processes, wherein the execution results in the generation of an information,
forwarding the information of the executed process to the supervising entity or safety module,
evaluating the received information by the supervising entity or safety module, and
executing a second process of the sequence of processes depending on the result of the evaluation;wherein identifiers are assigned to the processes of the sequence, wherein the supervising entity or the safety module is operable to access a sequence table, wherein the sequence table comprises entries specifying allowed sequences of processes, wherein the information comprises the identifier of the second process, wherein the supervising entity or the safety module verifies whether the second process may be executed subsequent to the first process by looking up the sequence table, and wherein in response to determining that the second process is not allowed to be executed subsequent to the first process the supervising entity or safety module interrupts the execution of the sequence.

US Pat. No. 10,166,331

AUTOMATIC CLOSED-LOOP CONTROL ADJUSTMENTS AND INFUSION SYSTEMS INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. A method of operating an infusion device comprising a motor operable to deliver a fluid to a user, the method comprising:identifying a condition of the user that is likely to influence a response to the fluid in a body of the user;
classifying the condition as exercise; and
after classifying the condition as exercise:
estimating an amount of energy expenditure during the exercise;
calculating a change in glycemic level for the user based on the amount of energy expenditure;
determining an equivalent insulin amount based on the change in glycemic level;
determining an adjusted proportional gain coefficient based on a first difference between a daily insulin requirement for the user and the equivalent insulin amount;
determining a delivery command by applying the adjusted proportional gain coefficient to a second difference between a measured glucose value obtained from a glucose sensing arrangement and a target blood glucose; and
operating the motor of the infusion device in accordance with the delivery command to deliver the fluid to the user in accordance with the adjusted proportional gain coefficient.

US Pat. No. 10,166,330

PHARMACEUTICAL DRUG DELIVERY SYSTEM

1. A pharmaceutical drug delivery system having a heater, a base comprising at least two inlets, an outlet and a passive mixing chamber having micro pin fins with heights in the range of 10 to 100 ?m, wherein the micro pin fins enhance heat transfer from the heater and promote passive mixing by generating turbulence within a flowing fluid mixture thereby providing an even distribution of temperature and concentration within the passive mixing chamber, wherein a surface portion of the base is coated with a coating material different from a material of said surface portion of the base, wherein a height of said coating material from said surface portion of the base is in nano scale, wherein distribution of said coating material throughout said surface portion of the base varies from the inlets towards the outlet such that the surface portion of the base comprises a plurality of regions R1 to RN each having a different distribution of the coating material relative to each other, thereby establishing a surface tension gradient among regions R1 to RN for promoting fluid flow towards the outlet.

US Pat. No. 10,166,327

SMART CONNECTION INTERFACE

Medtronic MiniMed, Inc., ...

1. A connector interface system, comprising:a cap to connect to a reservoir to form a reservoir/cap unit for installation into an infusion pump device; and
at least two different types of detectable features arranged on the cap for detection by at least one sensor element on the infusion pump device when the reservoir of the reservoir/cap unit is received in a reservoir receptacle of the infusion pump device,
wherein the at least two different types of detectable features include at least one detectable parameter that is associated with one or more characteristics of the cap, the reservoir, a cannula, or a tubing connected between the cap and the cannula;
wherein the one or more characteristics of the cap, the reservoir, the cannula, or the tubing includes a type or identity of a manufacturer of the cap, the reservoir, the cannula or the tubing, or a size of the cap, the reservoir, the cannula or the tubing;
wherein a first of the at least two different types of detectable features includes a magnetically detectable feature that is attached to a housing of the cap; and
wherein the at least two different types of detectable features are detected by the at least one sensor element when the cap is in a proper or fully installed position within the reservoir receptacle of the infusion pump device.

US Pat. No. 10,166,325

PACKAGING FOR MEDICAL DEVICE AND MEDICAMENT

Sanofi, Paris (FR)

19. A method comprising:pivoting a first region and a second region of a packaging body relative to one another about a hinge of the packaging body from a storage position in which the first and second regions are spaced apart to a loading position in which the first region lies adjacent to the second region; and
causing a medicament container in the second region to be loaded into a chamber of a medicament delivery device in the first region by the first and second regions being pivoted into the loading position, the medicament delivery device comprising a delivery mechanism for administering medicament to a patient.

US Pat. No. 10,166,318

SYSTEM AND METHOD FOR CONTROLLING THE POSITION OF A LEVITATED ROTOR

TC1 LLC, Pleasanton, CA ...

1. A method of operating a blood pump, wherein the method comprises:applying a rotating magnetic field with a stator to rotate a rotor;
applying a first axial force on the rotor;
applying at least a second axial force on the rotor with the stator, wherein a combination of the first axial force and at least the second axial force suspends the rotor at a first balanced position; and
modifying a plurality of phase voltages provided to the stator to modify the second axial force such that the rotor is moved from the first balanced position to a second balanced position, wherein the second balanced position is different than the first balanced position.

US Pat. No. 10,166,311

TWIST ACTIVATED DISPENSER

F-MATIC, INC., Lehi, UT ...

1. A dispenser comprising:a container for storing a fluid, the container including a cap with a breakable seal, the cap attached to the container at a first end;
a lid fixedly attached to a second end of the container, the lid having a set of vents;
an absorbing device disposed around the outside of the container and cap;
a cage structure attached to the lid and a base, the cage structure, lid and base collectively being configured to enclose the container, cap and absorbing device;
the base including a set of blades positioned inside the base and aligned with the breakable seal in the cap; and
the cage structure and base being connected with a rotational connection, when rotated with respect to each other, the cage structure and base are drawn together, collapsing the dispenser on itself and pulling the set of blades into the container and puncturing the breakable seal.

US Pat. No. 10,166,306

CONTAINERS AND SYSTEMS FOR PROCESSING A FLUID

Life Technologies Corpora...

1. A container comprising:a first wall comprised of a polymeric material;
a second wall comprised of a polymeric material; and
a plurality of elongated baffles, spacers or seam lines formed between the first wall and the second wall and securing together the first wall and the second wall along a majority of a length of the first wall and the second wall so as to form a plurality of separate, elongated fluid flow paths, each of the plurality of fluid flow paths being separated from the other fluid flow paths by at least one of the baffles, spacers or seam lines, each of the plurality of fluid flow paths having a first end in fluid communication with an inlet and having a second end in fluid communication with an outlet.

US Pat. No. 10,166,305

MOBILE STERILIZATION APPARATUS AND METHOD FOR USING THE SAME

PMBS, LLC, Nutley, NJ (U...

1. A mobile sterilization system comprising:a sterilization cabinet, the sterilization cabinet comprising:
a bottom panel, a top panel, two side panels, a back panel and a door configured so as to define an interior chamber;
a plurality of casters or wheels mounted to the bottom panel each having a lateral projection;
at least one of the bottom panel, top panel and two side panels having a perforated area; and
at least one filter configured to cover the perforated area; and
a transfer cart comprising:
an upper platform for receiving the sterilization cabinet, the upper platform comprising a pair of transfer cart tracks extending longitudinally along the upper platform, wherein each of the transfer cart tracks comprises a lateral projection; and
a lower support structure for supporting the upper platform and for receiving wheels;
wherein the sterilization cabinet is received on the transfer cart such that the lateral projections of the caster or wheel brackets engage the lateral projections of the transfer cart tracks to prevent side-to-side and up-and-down movement of the sterilization cabinet relative to the transfer cart.

US Pat. No. 10,166,301

CHELATED PSMA INHIBITORS

CANCER TARGETED TECHNOLOG...

1. A method for preparing a compound of the formulaor a pharmaceutically acceptable salt thereof, whereinR comprises a divalent linking group bonded to a chelating agent, wherein the divalent linking agent comprises
whereinL2 is —(CH2)tN(H)-*, wherein
t is 1 to 30; and
the *-end is attached to the chelating agent;
L3 is #-(CH)u—C(O)—, #-(CH2)u—Z-Y—C(O)—, #-C(O)—(CH2)u—C(O)— or #-C(O)—(CH2)u—Z-Y—C(O)—, wherein
u is 1 to 30; and
the # end of L3 is attached to the dibenzocyclooctyne or triazolyl group above;
Y is **-CH2CH2—(OCH2CH2)n—, wherein
n is 1-20; and
the **-end is attached to Z; and
Z is —C(O)O—, —C(O)N(R00)-, —OC(O)—, —N(R00)C(O)—, —S(O)2N(R00)-, —N(R00)S(O)2—, —OC(O)O—, —OC(O)N(R00)-, —N(R00)C(O)O—, or —N(R00)C(O)N(R00)-, wherein each R00 is independently hydrogen or C1-C6 alkyl;and —(C(O)(CH2)p—(C(O))0-1—NH)-*, whereinp is 1 30; and
the *-end is attached to L3,wherein the chelating agent is optionally associated with a PET-active or therapeutic radioisotope,the method comprisingreacting an azide terminated chelating agent optionally associated with a PET-active or therapeutic radioisotope with a DBCO-modified PMSA inhibitor of the formula

wherein
R comprises a DBCO-modified divalent linking group comprising
whereinL3 is #-(CH2)u—C(O)—, #-(CH2)u—Z-Y—C(O)—, #-C(O)—(CH2)u—C(O)— or #-C(O)—(CH2)u—Z-Y—C(O)—, wherein
u is 1 to 30;
the # end of L3 is attached to the dibenzocyclooctyne or triazolyl group above;
Y is **-CH2CH2—(OCH2CH2)n—, wherein
n is 1-20; and
the **-end is attached to Z; and
Z is —C(O)O—, —C(O)N(R00)-, —OC(O)—, —N(R00)C(O)—, —S(O)2N(R00)-, —N(R00)S(O)2—, —OC(O)O—, —OC(O)N(R00)-, —N(R00)C(O)O—, or —N(R00)C(O)N(R00)-, wherein each R00 is independently hydrogen or C1-C6 alkyl;and —(C(O)(CH2)p—(C(O))0-1—NH)-*, whereinp is 1-30; and
the *-end is attached to L3.

US Pat. No. 10,166,298

LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS

Acuitas Therapeutics, Inc...

1. A compound having the following structure (IE):
or a pharmaceutically acceptable salt or stereoisomer thereof, wherein:
G1 and G2 are each independently unsubstituted alkylene;
G3 is unsubstituted C1-C12 alkylene;
R1 and R2 are each independently C6-C24 alkyl;
R3 is OR5, CN, —C(?O)OR4, —OC(?O)R4 or NR5C(?O)R4;
R4 is C1-C12 alkyl; and
R5 is H or C1-C6 alkyl.

US Pat. No. 10,166,296

HAPTENS OF ARIPIPRAZOLE

Janssen Pharmaceutica NV,...

1. A compound of Formula I:
wherein:
R1 is H,

R2 is H or

R3 is H; provided that either R1 or R2 must be H, and further provided that both R1 and R2 may not be H simultaneously;
m is 1, 2, 3, 4, or 5; and
n is 1, 2, 3, 4, or 5.

US Pat. No. 10,166,295

PEGYLATED OXM VARIANTS

OPKO Biologics Ltd., Kir...

1. A method for the preparation of an oxyntomodulin (OXM) conjugate represented by the structure of formula II:
wherein R2 is H or SO3H;
said method comprises:
reacting MAL-Fmoc-NHS (R2?H) represented by the following structure:

MAL-FMS-NHS (R2?SO3H) represented by the following structure:

with a resin-bound oxyntomodulin of SEQ ID NO:1, wherein the amino side chains of Lys12 and Lys30 of said resin-bound oxyntomodulin are each protected by a protecting group, to obtain a resin-bound MAL-Fmoc-protected OXM or a resin-bound MAL-FMS-protected OXM, respectively;
followed by
(b) reaction of the resin-bound MAL-Fmoc-protected OXM or the resin-bound MAL-FMS-protected OXM with sulfhydryl PEG polymer (PEG-SH) and subsequently removing the protecting groups and said resin; or
(c) removal of the protecting group and the resin to provide MAL-Fmoc-OXM and a MAL-FMS-OXM, respectively, and subsequent reaction of the MAL-Fmoc-OXM or the MAL-FMS-OXM with sulfhydryl PEG polymer (PEG-SH);
to yield the structure of formula II, wherein the amino residue of His1 of said OXM is linked to said Fmoc or FMS.

US Pat. No. 10,166,291

TARGETED NANOPARTICLES

California Institute of T...

1. A polymer conjugate comprising a polymer containing a polyol and a polymer containing a nitrophenylboronic acid,wherein the polymer containing the nitrophenylboronic acid has a linkage cleavable under reducing conditions and is conjugated to the polymer containing the polyol with a reversible borate ester linkage, and
wherein the polymer containing the polyol is derived from the coupling of a compound of Formula A with a compound of Formula B;whereinthe compound of Formula A is:
in whichthe spacer is independently selected from any organic group;
the amino acid is selected from any organic group bearing a free amine and a free carboxylic acid group;
n is 1-20; and
Z1 is independently selected from —NH2, —OH, —SH, and COOH; andthe compound of Formula B is:in whichq is a number from 1 to 20;
p is a number from 20 to 200; and
L is a leaving group.

US Pat. No. 10,166,249

SUBSTITUTED BICYCLIC COMPOUNDS

Bristol-Myers Squibb Comp...

1. A compound of Formula (III):
or a salt thereof, wherein:
R1 is —OH or —OP(O)(OH)2;
R2a is —(CH2)3-6CH3, —(CH2)1-4CH?CRxRx, —(CH2)1-4CH?CRx(CH2CH3), —CH?CH(CH2)1-3C(Rx)3, —CH?CH(CH2)1-3OCH3, —(CH2)1-3CH?CHCH?CRxRx, —CH?CH(CH2)1-3CH?CRxRx, —CH?CHRz, —(CH2)1-3Rz, —(CH2)1-3O(CH2)0-3Rz, —(CH2)1-3 S(CH2)0-3Rz, —CH2S(O)Rz, —CH2S(O)2Rz, —O(CH2)1-2Rz, —O(CH2)1-2O(CH2)0-2Rz, —OC(O)Rz, —(CH2)1-4O(CH2)0-9C(Rx)3, —(CH2)1-4O(CH2)0-9CF3, —(CH2)1-4CRxRxO(CH2)0-4C(Rx)3, —(CH2)1-3O(CH2)1-4CH?CRx(CH2)0-3CH3, —(CH2)1-3O(CH2)1-4CH?CRxRx, —(CH2)1-3O(CH2)1-4C (OH)RxRx, —(CH2)1-3O(CH2)1-4O(CH2)0-3CH3, —(CH2)1-3 S(CH2)0-4C(Rx)3, —(CH2)0-3O(CH2)1-4S(CH2)0-3C (Rx)3, —(CH2)1-3 S(CH2)1-4Si(CH3)3, —(CH2)1-3S(O)(CH2)0-4C(Rx)3, —(CH2)1-3S(O)2(CH2)0-4C(Rx)3, —(CH2)1-5NRxRx, —O(CH2)1-7C (Rx)3, —O(CH2)1-4O(CH2)0-4C(Rx)3, —O(CH2)1-4CH?CRX(CH2)1-3CH3, —O(CH2)1-4O(CH2)0-3C(Rx)3, —O(CH2)1-4O(CH2)1-3CH?CRxRx, —O(CH2)1-4O(CH2)1-3C?CRx, —C(O)(CH2)0-4C(Rx)3, —OC(O)(CH2)0-4C(Rx)3, —OC(O)CRxRx(CH2)0-4C(Rx)3, —OC(O)NRx(CH2)0-5C(Rx)3, —NRxC(O)NRx(CH2)0-5C(Rx)3, —C(CH3)?N—O(CH2)0-5C(Rx)3, —C(CH3)?N—O(CH2)1-2(phenyl), —C(CH3)?N—O(CH2)1-2(fluorophenyl), —C(CH3)?N—O(CH2)1-2(methoxyphenyl), phenyl, or pyridinyl;
each Rx is independently H or —CH3; and
Rz is phenyl, imidazolyl, pyrazolyl, pyridinyl, pyrimidinyl, pyrazinyl, quinolinyl, thiophenyl, thiazolyl, oxetanyl, C3-6 cycloalkyl, adamantanyl, or tetrahydropyranyl, each substituted with zero to 4 substituents independently selected from F, Cl, I, C1-4 alkyl, —O(C1-3 alkyl), —CF3, —OCF3, —(CH2)1-6OCH3, —CH2NRxRx, —C(O)NRxRx, —C(O)NRx(C1-4 alkyl), and —CH2C(O)NRxRx.

US Pat. No. 10,166,248

METHODS OF PREVENTING PLATELET ACTIVATION

Vanderbilt University, N...

1. A method of reducing the occurrence of malondiadehyde protein modification in a subject in need thereof, comprising:identifying a subject with increased platelet activation;
administering to said subject a malondiadehyde adduct formation reducing amount of a compound of the following formula:

or a pharmaceutically acceptable salt thereof;
to thereby reduce said protein modification.

US Pat. No. 10,166,246

TGR5 AGONIST COMPLEXES FOR TREATING DIABETES AND CANCER

City of Hope, Duarte, CA...

1. A complex of the following structure:

US Pat. No. 10,166,241

COMBINATION THERAPY III

Turun yliopisto, Turun y...

1. A combination of at least one type of HDAC4 silencing agent and a compound of Formula (I):
wherein
R? is H or alkyl;
R? is H or alkoxy;
R1 and R2 are H or together form oxo;
R3 and R4 are independently H, OH or together form oxo:
R5, R6, R6?, R7, and R8 are independently selected from the group consisting of H, alkyl, alkoxy, hydroxy, hydroxylalkyl, alkoxycarbonyl, or mono- and dialkylamino;
X is CH2 or O; and
n is 0 or 1.

US Pat. No. 10,166,221

FORMULATIONS OF AN LSD1 INHIBITOR

Incyte Corporation, Wilm...

1. A pharmaceutical formulation in solid oral dosage form comprising:(a) an inhibitor of LSD1 which is Compound 1 di-tosylate salt of the formula:

or a solvate or hydrate thereof, and
(b) an organic acid selected from the group consisting of ascorbic acid, citric acid, fumaric acid, lactic acid, maleic acid, malic acid, sorbic acid, succinic acid, tartaric acid, and hydrates or solvates thereof, wherein the organic acid is from about 1% and to about 50% by weight.

US Pat. No. 10,166,185

EXCIPIENT AND ORAL SOLID DOSAGE FORMS FOR OILY DRUGS

1. An excipient composition, consisting of microcrystalline cellulose and silicate-based adsorbent carrier selected from the group consisting of a magnesium aluminometasilicate, a granular hydrophilic fumed silica, and a mixture thereof, and optionally a colloidal silicon dioxide, wherein the amount of silicate-based adsorbant carrier is from about 10% to about 35% by weight of the excipient composition.

US Pat. No. 10,166,176

PLASMONIC ENHANCEMENT OF ABSORPTION IN SUNSCREEN APPLICATIONS

International Business Ma...

1. A method, comprising:providing multiple zinc oxide particles;
completely enclosing nine or more metal particles within each of the multiple zinc oxide particles, wherein each of the multiple zinc oxide particles has a size of less than 400 nanometers in diameter, and wherein the nine or more metal particles are each physically separated within each of the multiple zinc oxide particles by a distance of approximately 100 nanometers and 200 nanometers; and
embedding the multiple zinc oxide particles, each with nine or more completely enclosed metal particles therein, into one or more silicon dioxide particles, wherein each of the one or more silicon dioxide particles has a size of between 0.8 and 2 micrometers in diameter.

US Pat. No. 10,166,171

ACUPUNCTURE DEVICE AND NEEDLE WAKENING METHOD

BOE Technology Group Co.,...

1. An acupuncture device, comprising a plurality of acupuncture needles, each acupuncture needle comprising a needle body and a needle handle, an end of the needle body being a needle tip, and the other end of the needle body being fixedly connected with the needle handle; whereinthe acupuncture device further comprises a driving device, and the driving device comprises a driving component and a first timing component;
the first timing component is configured for setting an interval of time to start the driving component;
the driving component is configured for driving an acupuncture needle to rotate alternately in forward and reverse directions when the interval of time is arrived;
the driving component comprises a connecting plate, a lifting rod and a swing motor, and the lifting rod and the swing motor are connected with the connecting plate;the connecting plate is provided with a first connecting part, and the needle handle of each acupuncture needle is provided with a second connecting part;the first connecting part is capable of being detachably connected with the second connecting part;
the first connecting part comprises a plurality of hooks arranged on a surface of the connecting plate connected to the plurality of acupuncture needles;
the second connecting part comprises a through hole arranged on the needle handle; or, the second connecting part comprises a groove arranged on a side edge of the needle handle; and
a number of the hooks is greater than a number of the acupuncture needles applied to human acupoints.

US Pat. No. 10,166,148

SURGICAL CAVITY DRAINAGE AND CLOSURE SYSTEM

University of Massachuset...

1. A negative pressure surgical drain device comprising a plurality of drain tubes positioned in contact with a surface of an adhesion matrix, the adhesion matrix comprising a layer of porous biodegradable material having a wound conforming shape and comprising a plurality of spaced apertures formed through the layer of the adhesion matrix, the apertures being configured to allow tissue contact through the layer of the adhesion matrix upon implantation into an open wound such that a first tissue surface on a first side of the layer of the adhesion matrix can contact a second tissue surface on a second side of the layer of the adhesion matrix through the plurality of apertures during application of negative pressure to the wound, the drain tubes being positionable at tube receiving regions of the layer of the adhesion matrix between the spaced apertures and wherein the drain tubes are configured to be removed from contact with the surface of the layer of the adhesion matrix after application of negative pressure to the adhesion matrix, the adhesion matrix being configured to remain in the wound upon removal of the drain tubes from the wound.

US Pat. No. 10,166,138

OSTOMY APPLIANCE

Convatec Technologies, In...

1. A stoma adapter comprising:a substantially unobstructed tubular passageway for expulsion of effluent with a proximal end for attachment in or around a stoma and a distal end for discharge of waste, the distal end comprising a flange,
a flexible tubular wall surrounding said entire tubular passageway, said flexible tubular wall having at least one axial reinforcement element for reinforcing said flexible tubular wall in an axial direction to provide axial stiffness along the entire tubular passageway and permit flexing of the flexible tubular wall in a radial direction, and
a one-way valve, wherein the one-way valve prevents re-entry of discharged waste into the distal end of the tubular passageway, wherein the one-way valve is openable from a closed position by pressure of the effluent when a bowel forces the expulsion of the effluent, wherein the one-way valve is disposed at the distal end.

US Pat. No. 10,166,136

METHOD OF IMPLANTING A PENILE PROSTHETIC

1. A method of implanting a penile prosthetic, the method comprising:providing a tool having a barrel extending from a proximal end to a distal end, with the barrel having a first groove formed in an exterior surface of the barrel and a second groove formed in the exterior surface of the barrel and located apart from the first groove, with the first groove and the second groove extending to and forming an opening at the distal end of the barrel;
deflating an inflatable penile implant to provide a deflated penile implant;
inserting a first lateral edge of the deflated penile implant into the first groove and inserting a second lateral edge of the deflated penile implant into the second groove;
placing the barrel of the tool and the deflated penile implant into a corpora cavernosum of a penis;
sliding the barrel of the tool relative to the deflated penile implant, removing the barrel from the corpora cavernosum of the penis, and leaving the deflated penile implant in the corpora cavernosum of the penis.

US Pat. No. 10,166,135

POSTURE CORRECTIVE BRACE

GIKEN INC., Hatsukaichi ...

1. A posture corrective brace including a device for correcting asymmetry of the pelvis configured to be attached to a body such that the device surrounds the circumference of the pelvis of the body, the posture corrective brace comprising:an innominate front compression part capable of abutting an abdominal part near the front side of the right or left innominate, and an innominate rear compression part capable of abutting the pelvis near the rear side of the right or left innominate; and
at least one body brace configured to be attached to the body such that the at least one body brace surrounds the circumference of the pelvis of the body, the at least one body brace including a front frame in a substantially belt-like shape configured to be laterally extended on the abdominal part of the front side of the body, two first belt winding mechanisms vertically disposed on the left end of the front frame on the external side thereof, two second belt winding mechanisms vertically disposed on the right end of the front frame on the external side thereof, and two unstretchable fastening belts each having one end fastened to each of the two first belt winding mechanisms and the other end fastened to each of the two second belt winding mechanisms, wherein
the innominate front compression part includes a first front pad disposed on the left end of the front frame on the internal side thereof and a second front pad disposed on the right end of the front frame on the internal side thereof, the first front pad and the second front pad having body contact surfaces each shaped as an inclined surface formed so as to press the front side of the right or left innominate such that the innominate can be guided from a forward external side to a backward central side, wherein
the innominate rear compression part includes a back frame laterally extended so as to compress the rear of the right and left innominates, a first back pad disposed on the left end of the back frame on the internal side thereof, a second back pad disposed on the right end of the back frame on the internal side thereof, and belt insertion portions configured to allow the two fastening belts to be inserted thereinto vertically and separately, the belt insertion portions disposed at positions on the back frame on the external side thereof interposed between the first back pad and the second back pad, the two fastening belts being inserted into the belt insertion portions, the first back pad and the second back pad having body contact surfaces each shaped as an inclined surface formed so as to press the rear side of the right or left innominate such that the innominate can be guided from a backward external side to a central side, and wherein
when in use,
the body is fastened by the upper side of the first front pad and the upper side of the first back pad on the left side of the body, on a priority basis, when the upper fastening belt of the first belt winding mechanism out of the two fastening belts is operated in a winding direction;
the body is fastened by the lower side of the first front pad and the lower side of the first back pad on the left side of the body, on a priority basis, when the lower fastening belt of the first belt winding mechanism out of the two fastening belts is operated in a winding direction;
the body is fastened by the upper side of the second front pad and the upper side of the second back pad on the right side of the body, on a priority basis, when the upper fastening belt of the second belt winding mechanism out of the two fastening belts is operated in a winding direction; and
the body is fastened by the lower side of the second front pad and the lower side of the second back pad on the right side of the body, on a priority basis, when the lower fastening belt of the second belt winding mechanism out of the two fastening belts is operated in a winding direction.

US Pat. No. 10,166,134

ADJUSTABLE, MULTI-AXIS STABILIZER APPARATUS AND METHOD

1. An improved adjustable, multi-axis, motion stabilizer apparatus comprising:a. a first curved cup with a curved radius, the first curved cup with an inside surface and an outside surface;
b. a cup hole through said first curved cup;
c. a second curved cup with a curved radius wherein said curved radius of said second curved cup is approximately equal to the curved radius of said first curved cup, the second cup with an inside surface and an outside surface wherein said outside surface of said second curved cup fits with the inside surface of said first curved cup;
d. a cup hole in said second curved cup;
e. a cup pin conformed to fit with said cup holes and connect said first curved cup with said second curved cup wherein said cup pin includes a cap and a shaft;
f. a rotation slot in said first curved cup; wherein said rotation slot includes an outer edge and an inner edge with the rotation slot formed thereby in between and further wherein said rotation slot includes at least one pin hole in said outer edge and at least one pin hole in said inner edge;
g. a limit boss in said second curved cup wherein said limit boss is configured to fit within said rotation slot; and
h. a rotation slot pin wherein said rotation slot pin is configured to fit within said at least one outer edge pin hole and connect said at least one outer edge pin hole with said at least one inner edge pin hole across said rotation slot and restrict movement of said limit boss within said rotation slot.

US Pat. No. 10,166,133

DEVICE FOR INTERMITTENTLY OBSTRUCTING A GASTRIC OPENING

BAROnova, Inc., San Carl...

1. An obstructing member for intermittently obstructing a pyloric valve, comprising:a coiling occluding member having a low-profile configuration wherein the coiling occluding member forms a helical structure extending longitudinally and wherein the coiling occluding member is configurable into a deployment configuration having a plurality of turns which nest one adjacent to the other forming a wound structure in the deployment configuration;
a locking mechanism in communication with the coiling occluding member when the coiling occluding member is in the deployment configuration, wherein the locking mechanism is configured to secure the coiling occluding member in the deployment configuration; and
a covering member which at least partially surrounds the coiling occluding member in its deployment configuration.

US Pat. No. 10,166,132

SYSTEMS AND METHODS FOR MAGNETICALLY POSITIONING A GASTRIC DEVICE

Appetec, Inc., Macon, GA...

1. A method of inducing a feeling of satiety comprising the steps of: transesophageally inserting a deployable intragastric device containing magnetic material into a stomach of a patient, wherein the intragastric device is not attached to a body part of the patient; andpositioning an external magnet in close enough proximity to the intragastric device to create a sufficient magnetic pulling force between the external magnet and the intragastric device to move the intragastric device towards, and impart stimulating force upon, a stomach wall of the patient, wherein the patient positions the external magnet and the stimulating force is applied for a therapeutically sufficient period of time to induce satiety.

US Pat. No. 10,166,131

PROCESS FOR LOADING A STENT ONTO A STENT DELIVERY SYSTEM

ABBOTT LABORATORIES VASCU...

1. A stent delivery system having a contracted delivery configuration and an expanded deployed configuration, the stent delivery system comprising:a stent having a plurality of expandable elements and a plurality of interstices disposed between adjacent expandable elements; and
a delivery catheter having an inflatable balloon comprising creases extending non-uniformly within the interstices of the stent in the contracted delivery configuration, each crease defining a maximum radial height within a corresponding interstice, wherein the maximum radial heights of the creases vary.

US Pat. No. 10,166,129

BIOABSORBABLE STENT AND TREATMENT THAT ELICITS TIME-VARYING HOST-MATERIAL RESPONSE

ABBOTT CARDIOVASCULAR SYS...

1. A method of treating coronary artery disease, comprising:identifying a segment of a blood vessel that is stenotic in a patient in need of treatment of coronary artery disease (CAD);
positioning a bioabsorbable scaffold at the segment, wherein the scaffold is composed of a pattern of struts made of poly(L-lactide) (PLLA) having a weight average molecular weight of 150 to 200 kg/mol;
increasing a diameter of the segment to a reference vessel diameter by expanding the segment with the bioabsorbable scaffold, wherein the reference vessel diameter of the segment is 3 mm and a % diameter stenosis of the segment prior to positioning the bioabsorbable scaffold at the segment and expanding the segment is greater than 50%;
supporting the segment with the bioabsorbable scaffold for less than 6 months after the increasing, wherein a compliance of the segment during the supporting is less than a natural compliance of a healthy blood vessel, wherein radial strength of the scaffold sufficient for the supporting is provided by a strut thickness of 100 to 200 microns, and a degree of crystallinity of the scaffold of 25 to 50%;
wherein a vessel wall of the segment undergoes remodeling during the supporting, the remodeling comprising reinforcement of the vessel wall due to matrix deposition in a neointima layer of the vessel wall so that the segment is maintained at an increased diameter after the supporting;
restoring the compliance of the segment after the remodeling to the natural compliance of the healthy blood vessel; and
restoring vasomotion to the segment after the remodeling as the compliance of the segment after the remodeling is restored to the natural compliance of the healthy blood vessel.

US Pat. No. 10,166,128

LATTICE

1. A lattice comprising:a generally tubular member having a plurality of segments arranged to define a plurality of openings therein, the tubular member having a luminal surface and an opposite exterior surface,
wherein at least said plurality of segments of said tubular member comprises a composite material including at least one fluoropolymer membrane and an elastomer, wherein said at least one fluoropolymer membrane is configured in a retracted state such that the fluoropolymer membrane includes a microstructure comprising serpentine fibrils and is characterized by an absence of visible pleating, folding, or wrinkling of the fluoropolymer membrane, and wherein each of said serpentine fibrils has a width of 1.0 micron or less, the tubular member being transitionable from a reduced diameter in which the serpentine fibrils define a plurality of curved sections and an expanded diameter in which the serpentine fibrils define a substantially straight orientation, the tubular member being more resistant to further expansion once the expanded diameter is achieved.

US Pat. No. 10,166,127

ENDOLUMINAL DEVICE AND METHOD

Intact Vascular, Inc., W...

1. A system for delivering a vascular prosthesis, the system comprising:an elongate body comprising a proximal end, a distal end, and a plurality of longitudinally fixed delivery platforms disposed adjacent the distal end, each delivery platform of the plurality of delivery platforms comprising a platform length and being separated from each adjacent delivery platform of the plurality of delivery platforms by a platform separation distance;
a marker portion at the proximal end of the elongate body, the marker portion comprising a plurality of markings comprising a number of markings equal to the number of delivery platforms in the plurality of delivery platforms;
a sheath comprising a proximal end, a distal end, and a sheath elongate body extending between the proximal end of the sheath and the distal end of the sheath,
wherein the sheath surrounds at least a portion of the elongate body and is moveable with respect to the elongate body, the sheath having a first position and a second position,
wherein when in the first position the distal end of the sheath is disposed distal to a distal end of a distalmost delivery platform of the plurality of delivery platforms such that all delivery platforms of the plurality of delivery platforms are covered by the sheath, and
wherein when in the second position the distal end of the sheath is disposed proximal to at least the proximal end of the distalmost delivery platform of the plurality of delivery platforms such that at least the distalmost delivery platform of the plurality of delivery platforms is not covered by the sheath, and
a plurality of vascular prostheses, each vascular prosthesis of the plurality of vascular prostheses being disposed at a corresponding delivery platform of the plurality of delivery platforms;
a selector coupled to the proximal end of the sheath, wherein the selector is configured to move with respect to the elongate body and the marker portion when the sheath moves with respect to the elongate body, wherein longitudinal alignment of a portion of the selector and a marking of the plurality of markings indicates at least one of a number of vascular prostheses left to be deployed and the number of vascular prostheses already deployed.

US Pat. No. 10,166,126

INFLATABLE BALLOON STENT

BOSTON SCIENTIFIC SCIMED,...

1. A stent, the stent comprising:an elongated tubular balloon having a first end and a second end and an intermediate region disposed therebetween, the elongated tubular balloon having a lumen extending from the first end to the second end;
an inflation chamber extending continuously from the first end to the second end of the elongated tubular balloon, the inflation chamber including a first flared portion at the first end, a second flared portion at the second end, and a body portion therebetween, wherein the body portion of the inflation chamber is defined between a radially outward wall and a radially inward wall of the inflation chamber, the radially inward wall defining the lumen of the elongated tubular balloon through a length of the elongated tubular balloon;
an outer layer disposed over at least a portion of an outer surface of the outer wall;
a plurality of holes positioned adjacent to the first and/or second ends of the elongated tubular balloon and extending from an outer surface of the outer layer to the outer surface of the outer wall, the plurality of holes configured to contact a body lumen when the elongated tubular balloon is in an expanded configuration; and
an inflation valve.

US Pat. No. 10,166,125

TRANSDERMAL INTRAOSSEOUS DEVICE

Biomet Manufacturing, LLC...

1. A transdermal intraosseous device comprising:a transdermal adapter having a longitudinal axis and configured for connection to an external prosthetic device for use with a bone of a patient, the transdermal adapter including:
a dome-shaped portion for transcutaneous implantation,
a porous metal dome-shaped structure at least partially overlaying the dome-shaped portion,
an external shaft extending from the dome-shaped portion, the external shaft including a polished external shaft portion, and
a dermal transition structure extending axially from the porous metal dome-shaped structure to the polished external shaft portion, the dermal transition structure including a first transitional surface treatment layer contiguous to a second transitional surface treatment layer such that a common border of the first and second transitional surface treatment layers is located along the longitudinal axis and each of the first and second transitional surface treatment layers extends along the external shaft distal of the dome-shaped portion, each of the first and second transitional surface treatment layers configured to directly contact a dermis layer of the patient for infection control upon implantation thereof, the first transitional surface treatment layer having a greater roughness than the second transitional surface treatment layer to provide a controlled roughness gradient from the external shaft to the dome-shaped portion for controlling infection at the dermis layer of the patient, wherein a first surface treatment of the first transitional surface treatment layer is different than a second surface treatment of the second transitional surface treatment layer; and
a bone fixator including a distal portion coupled to the transdermal adapter and a proximal portion configured for anchoring into the bone.

US Pat. No. 10,166,123

CONTROLLING PROSTHETIC DEVICES WITH SMART WEARABLE TECHNOLOGY

International Business Ma...

1. A computer program product for mode selection of a prosthesis, the computer program product comprising:one or more computer-readable storage media and program instructions stored on the one or more computer-readable storage media, the program instructions comprising:
program instructions to receive, by a wearable device, a first input from a user, wherein (i) the wearable device is a ring that comprises a rotatable housing with a touch surface sensitive surface, and (ii) the first user input comprises the user touching the touch surface;
program instructions to determine the first input indicates a change to a user-activated mode of operation of the prosthesis;
program instructions to send, by the wearable device, a first command to the prosthesis to change the user-activated mode of operation of the prosthesis;
in response to receiving the first command by the prosthesis, program instructions to operate one or more control devices of the prosthesis to change a user-activated current mode of operation of the prosthesis based, at least in part, on the determined user-activated mode of operation associated with the received first input;
program instructions to receive, by the wearable device, a second input from a user;
program instructions to determine, by the wearable device, the second input indicates an activation operation of the prosthesis;
program instructions to send, by the wearable device, a second command to the prosthesis to activate the prosthesis; and
in response to receiving the second command by the prosthesis, program instructions to operate the one or more control devices of the prosthesis to perform an action associated with the current user-activated mode of operation of the prosthesis.

US Pat. No. 10,166,121

BONE PRESERVING INTRAOPERATIVE DOWNSIZING SYSTEM FOR ORTHOPAEDIC IMPLANTS

Zimmer, Inc., Warsaw, IN...

1. A knee prosthesis system comprising:a first provisional component having a first articular surface and a first bone contacting surface disposed opposite the first articular surface, the first bone contacting surface comprising:
a first anterior surface defining a first, generally coronal anterior plane;
a first distal surface defining a first, generally transverse plane; and
a first posterior surface defining a first, generally coronal posterior plane, a first distance extending anteroposteriorly from said first posterior plane to said first anterior plane,
said first provisional component further comprising a posterior cut slot defining a posterior cut width and adapted to receive a cutting instrument;
a second component having a second articular surface defining a second articular surface geometry and a second bone contacting surface disposed opposite the second articular surface, the second bone contacting surface comprising:
a second anterior surface defining a second, generally coronal anterior plane;
a second distal surface defining a second, generally transverse plane; and
a second posterior surface in a second, generally coronal posterior plane, a second distance extending anteroposteriorly from said second posterior plane to said second anterior plane; and
said second distance less than said first distance by an amount equal to said posterior cut width.

US Pat. No. 10,166,119

DEVICE FOR FACILITATING ARTIFICIAL PROSTHESIS INSTALLATION WITH MEASURED APPLIED PRESSURE AND METHOD THEREFOR

Boyer Anderson, LLC, Hen...

1. A patella clamp, comprising:an upper frame arm;
a lower frame arm having a rear portion and a front portion, wherein the rear portion is movably connected to the upper frame arm; and
a patella clamp pressure measurement arrangement secured to at least one of the upper frame arm or the lower frame arm, wherein the clamp pressure measurement arrangement measures the pressure applied between the upper and lower frame arms to a patella construct, wherein the clamp pressure measurement arrangement comprises a turnable knob secured to the upper frame arm and a pivot nut threadedly engaged with the turnable knob.

US Pat. No. 10,166,118

SPIRAL ASSEMBLY TOOL

DEPUY SYNTHES PRODUCTS, I...

1. An assembly tool for assembly of a first component of a prosthesis to a second component of the prosthesis for use in joint arthroplasty, the tool comprising: a first member operably associated with the first component; and a second member operably associated with the second component; wherein the second member includes a cap having a threaded recess and further includes a threaded rod configured to engage the threaded recess so as to move the second member relative to the first member and the threaded rod is made of a harder metal than the threaded recess, wherein the second member includes a tensile bar that is sized and shaped to break at a predetermined force and the second member includes a housing configured to house the tensile bar, the housing including an upper restraint, a lower restraint, and a pivot pin coupling the upper restraint to the lower restraint, and the lower restraint including a slot, such that when the upper restraint is pivoted via the pivot pin, the tensile bar swings out of the slot in the lower restraint.

US Pat. No. 10,166,116

HELICAL LOCK SPACER, INSTRUMENTS AND METHODS

1. A method of implanting a bone spacer having a helical lock in an intervertebral space comprising the steps of:obtaining a bone spacer inserter instrument comprising an elongate shaft portion and a central locking rod portion;
positioning a coil driver over said elongate shaft portion of said bone spacer inserter;
loading a helical lock implant on a distal end of said elongate shaft portion wherein said elongate shaft portion occupies a central core space of said helical lock and wherein a cutting tip of said helical lock is orientated distally on said bone spacer inserter;
positioning a bone spacer implant against an engagement face disposed on a distal end of said elongate shaft portion;
advancing said locking rod portion into a spacer lock of said bone spacer thereby fixing said bone spacer implant to said bone spacer inserter instrument;
advancing the bone spacer and helical lock instrumentation assembly through an incision and into a predetermined position in an intervertebral space;
advancing through rotation said coil driver about its central axis thereby driving a tooth face on said coil driver to transmit torsional forces against a butt surface of a helix lock;
and continuing torsional forces on said coil driver until said helix lock is fully threaded into adjacent vertebral bone and said bone spacer.

US Pat. No. 10,166,111

SPINAL IMPLANTS AND RELATED APPARATUS AND METHODS

1. A spinal implant comprising:an outer corpus including a top-most surface, a bottom surface opposite the top surface, and a sidewall extending between the top surface and the bottom surface;
an inner corpus axially displaceably coupled to the outer corpus along a central axis extending through the inner corpus and the outer corpus, each of the inner corpus and the outer corpus having a cylindrical shape;
a transport admission provided on the sidewall of the outer corpus, the transport admission including an engagement structure, the transport admission having a first lateral length along an axis perpendicular to the central axis extending through the inner corpus and the outer corpus;
a lever admission provided on the inner corpus, the lever admission having a second lateral length along the axis perpendicular to the central axis, the second lateral length smaller than the first lateral length, the lever admission and the transport admission aligned about the central axis extending through the inner corpus and the outer corpus and arranged to receive a tool, the tool to distract the spinal implant, the lever admission including a set of teeth, the outer corpus including a flange, the flange including a portion of the engagement structure, a remainder of the engagement structure disposed between the inner corpus and the flange, the flange extending along the sidewall from the top surface to the transport admission; and
an alignment guide provided on the inner corpus and the outer corpus, the alignment guide including a tongue provided on the outer corpus and a groove provided on the inner corpus, the tongue and groove to allow an axial displacement of the inner corpus relative to the outer corpus and to prevent a rotation of the inner corpus relative to the outer corpus.

US Pat. No. 10,166,110

TOTAL ANKLE REPLACEMENT PROSTHESIS

Integra LifeSciences Corp...

1. An ankle replacement prosthesis, comprising:a tibial implant for implanting onto a tibia having a tibial-facing surface and a tibial implant lower surface opposite said tibial-facing surface and having an anterior end and a posterior end;
a talar implant for implanting onto a talus having a talar-facing surface and a talar implant upper surface opposite said talar-facing surface and having an anterior end and a posterior end;
an intermediate implant having an anterior end and a posterior end and a tibial-facing surface and a talar-facing surface, said intermediate implant fitting between said tibial implant and said talar implant;
wherein said tibial-facing surface of said intermediate implant fixedly attaches to said tibial implant and said talar-facing surface of said intermediate implant has an articulating surface that articulatingly engages said talar implant;
wherein said articulating surface of said intermediate implant has an anterior edge between an anterior planar surface and a bi-condylar surface at said anterior end thereof and a posterior edge between a posterior planar surface and said bi-condylar surface at said posterior end thereof;
wherein said anterior edge and said anterior planar surface are at a different elevation than said posterior edge and said posterior planar surface, with elevation being defined with respect to a top surface of said intermediate implant; and
wherein at least one of said anterior planar surface or said posterior planar surface is substantially parallel to said top surface.

US Pat. No. 10,166,109

PATIENT SPECIFIC BONE PREPARATION FOR CONSISTENT EFFECTIVE FIXATION FEATURE ENGAGEMENT

Stryker Corporation, Kal...

1. A method of performing surgery comprising:providing a prosthesis for implanting onto a bone of a joint of a patient, the prosthesis including a fixation peg having a peg radius and a peg length;
providing a mass of bone designed to be displaced by the fixation peg upon implantation of the prosthesis;
obtaining bone density data of a fixation area of the bone of the joint adapted to receive the fixation peg;
resecting a bore hole in the fixation area of the bone to receive the fixation peg, the bore hole having bore radius and a bore length, wherein the bore length is equal to the peg length and bore radius is based upon the obtained bone density data of the fixation area and the mass of bone designed to be displaced; and
implanting the prosthesis on the bone by inserting the fixation peg into the resected bore hole.

US Pat. No. 10,166,108

BUFFERABLE FEMORAL IMPLANT

Paonan Biotech Co., Ltd.,...

1. A bufferable femoral implant comprising:a femoral stem adapted to be implanted into a medullary cavity of a patient's femur;
said femoral stem including:
a metal main body adapted to be inserted into said medullary cavity of said femur, said metal main body including a plug member; a coupling rod connected with said plug member and longitudinally protruded downwardly from said plug member; said main body formed with a filling port, a plurality of distributing channels formed in said main body and fluidically communicated with said filling port, and a plurality of drain holes formed in a circumference of said main body and fluidically communicated with said distributing channels so as to lead a fixation agent filled into said filling port through said distributing channels to be released into the medullary cavity through said drain holes in said main body; and
an elastomer member integrally formed or connected with said coupling rod of said main body, and adapted to be inserted into said medullary cavity below said plug member;
said elastomer member including a plurality of grooves circumferentially recessed in said elastomer member to form a plurality of fins as interspersed with said plurality of grooves so as to make the elastomer member deformable or flexible in order to be well inserted into the medullary cavity of the femur to be squeezably compressibly or deformably embedded in the cavity for a firm or stable assembly of the elastomer member and the femoral implant with the femur;
whereby upon impacting by an external force on said femoral stem, said elastomer member will dampen or buffer a stress caused by the external force for protecting said femoral implant and the patient's femur.

US Pat. No. 10,166,106

METHODS AND DEVICES FOR A SURGICAL HIP REPLACEMENT PROCEDURE

1. A method of positioning a dummy implant relative to a greater trochanter of a femur to size the femur to receive a femoral component implant during a hip replacement surgical procedure, the method comprising:providing a dummy implant comprising a footplate at a proximal end with a cross-sectional size that replicates a proximal portion of the femoral component implant, a distal section with a cross-sectional size that replicates a distal portion of the femoral component implant, and an intermediate shaft that extends between the footplate and the distal section with a smaller cross-sectional size than an intermediate portion of the femoral component implant, the footplate extending radially outwardly beyond the shaft and the distal section having a distal end;
inserting the dummy implant into a femoral canal of the femur and contacting the distal section of the dummy implant against a wall of the femoral canal with the shaft extending along the femoral canal and being spaced away from the wall of the femoral canal and with the footplate of the dummy implant below a superior end of the greater trochanter and contacting against a proximal end of the femur;
determining an expected position of the femoral component implant relative to the femur based on visually observing a position of the footplate relative to the proximal end of the femur;
using the footplate as a cutting guide and moving a blade along a top edge of the footplate and cutting a portion of the femur that extends beyond the top edge of the footplate;
removing the dummy implant from the femoral canal; and
inserting the femoral component implant into the femoral canal.

US Pat. No. 10,166,105

SELF-DETACHING LAYER FOR EASY IMPLANT REMOVAL

DePuy Synthes Products, I...

1. A bone implant, comprising:a first layer provided over a first outer surface of the bone implant and including a first material which is one of water-soluble and degradable in body fluids, the first layer having a first thickness;
a second layer provided over an outer surface of the first layer and formed of a second, biocompatible material, the second layer having a second thickness smaller than the first thickness;
a third layer provided over an outer surface of the second layer, the third layer being formed of a material which is one of water-soluble and degradable in body fluids; and
a fourth layer provided over an outer surface of the third layer, the fourth layer being formed of a biocompatible material.

US Pat. No. 10,166,103

VALVE CUSP SIZER

Japanese Organization For...

1. A valve cusp sizer for determining a size of a valve cusp conforming to a size of a cardiac valve, comprising:a front surface (10) formed in an arcuate surface form to be abutted against an organism;
a back surface (20) positioned on an opposite surface side of the front surface (10); and
a pinching portion (30) protruding from the back surface (20) to be pinched by a surgical instrument,
wherein the front surface (10) is formed in the arcuate surface form in which a central part between left and right ends thereof projects toward a side of the organism.

US Pat. No. 10,166,100

SYSTEMS AND METHODS FOR DELIVERY OF ANNULOPLASTY RINGS

VALCARE, INC., Newport B...

1. A system for percutaneous, transcatheter heart valve repair, the system comprising:a catheter configured to provide percutaneous access into a heart of a patient;
an adjustable annuloplasty ring comprising:
a body member that is transitionable from an elongate insertion geometry to an annular operable geometry, the elongate insertion geometry configured to allow percutaneous passage of the annuloplasty ring, via the catheter, into the heart of a patient, and the annular operable geometry having an expanded state to conform to an annulus of a target valve of the heart and a contracted state to reduce a diameter of the annulus of the target valve,
a plurality of anchors deployable in the annular operable geometry to engage the annulus of the target valve; and
a stabilizer comprising a plurality of prongs configured to engage the annuloplasty ring after the body member has transitioned into the annular operable geometry within the heart to enable percutaneous manipulation of the ring to orient and position the ring in intimate contact with the annulus of the target valve.

US Pat. No. 10,166,098

SYSTEMS AND METHODS FOR TRANSCATHETER TREATMENT OF VALVE REGURGITATION

Middle Peak Medical, Inc....

1. A coaptation assist device for treating mal-coaptation of a heart valve, the heart valve having an annulus and posterior and anterior leaflets with an open configuration and a closed configuration, the coaptation assist device comprising:a frame;
a body coupled to the frame, the body having a first coaptation surface configured to be disposed toward the posterior leaflet, and an opposed second surface configured to be disposed toward the anterior leaflet;
two or more ribbons configured to extend from the frame, each ribbon comprising a single longitudinal strip having a first end and a second end, wherein each ribbon has only one end coupled to the frame and the other end spaced from the frame and a fixed length therebetween, each ribbon forming a generally U-shaped configuration comprising a first portion extending from the first end, a curve, and a second portion extending from the curve to the second end, the two or more ribbons comprising a shape memory material having a preformed shape, each ribbon movable from a first compressed configuration to a second expanded configuration, wherein the second expanded configuration is a deployed configuration of the coaptation assist device, wherein the second portion extends radially outward from the first portion in the second expanded configuration, wherein the two or more ribbons are configured to provide a compressive force, the compressive force sufficient to secure the coaptation assist device,
wherein the coaptation assist device defines a height extending from an outflow end of the heart valve to an inflow end of the heart valve, wherein at least one ribbon of the two or more ribbons is a ventricular ribbon and substantially extends along the height of the coaptation assist device, the ventricular ribbon configured to extend along the posterior leaflet, wherein the body is coupled to the ventricular ribbon and substantially extends along the height of the coaptation assist device, wherein the height is the entire longitudinal length of the device,
wherein the body of the coaptation assist device is configured to be positioned to allow the anterior leaflet to coapt against the body of the coaptation assist device when the coaptation assist device is in the second expanded configuration and positioned over the posterior leaflet.

US Pat. No. 10,166,096

FOLDABLE ACCOMMODATING INTRAOCULAR LENS

ForSight Vision6, Inc., ...

1. An accommodating intraocular lens (AIOL) system for implantation in a human eye, comprising:an accommodating intraocular lens comprising:
a housing defining, at least in part, a cavity, the housing formed of a first material;
an optical element contained within the cavity of the housing, the optical element capable of being deformed from a non-bulging state to a bulging state suitable for near vision, wherein the optical element is formed of a second material that is different from the first material, is flowable, and has a refractive index greater than a refractive index of aqueous humor; and
a piston reciprocally movable relative to the housing between an extended position and a compressed position, wherein the piston is adapted to be responsive to ciliary muscle contraction,
wherein application of a compression force on the optical element by the piston at a first location causes the optical element to bulge at a second location away from the first location to create the bulging state of the optical element; and
a self-anchoring haptics system extending in a plane perpendicular to a visual axis of the accommodating intraocular lens, the self-anchoring haptics system adapted to engage with ocular tissue to form at least two spaced-apart, stationary anchor points for retaining the accommodating intraocular lens in the eye.

US Pat. No. 10,166,095

INTRODUCER FOR A SIDE BRANCH DEVICE

Cook Medical Technologies...

1. A stent graft introduction arrangement in combination with a fenestrated stent graft,the fenestrated stent graft comprising a main tubular body, a distal end, a proximal end, a main lumen therethrough, at least one fenestration in the main body between the distal and the proximal end of the main body, and an internal side arm extending from the at least one fenestration and into the main lumen;
the introduction arrangement including an introducer, the introducer comprising a distal end intended to remain outside a patient in use and a proximal end, the proximal end of the introducer comprising a nose cone dilator and retention arrangement to retain the fenestrated stent graft thereon distally of the nose cone dilator, the fenestrated stent graft being retained on the introducer and a sheath on the introducer extending over the fenestrated stent graft to the nose cone dilator,
an indwelling catheter for each of said at least one fenestration, each indwelling catheter extending from the distal end of the introducer through an introducer lumen in the introducer to the fenestrated stent graft, the each indwelling catheter then exiting from the introducer lumen at a distal end of the fenestrated stent graft, the each indwelling catheter then extending outside and along the main tubular body, then entering the at least one the respective fenestration, extending through the internal side arm, and extending into the main lumen and toward the proximal end of the fenestrated stent graft, each the indwelling catheter configured to receive a guide wire extending therethrough,
whereby the indwelling catheter and the guide wire can be extended beyond the proximal end of the fenestrated stent graft in use after the sheath has been at least partially withdrawn from the fenestrated stent graft.

US Pat. No. 10,166,094

INTEGRATED EMBOLIC PROTECTION DEVICES

Emboline, Inc., Santa Cr...

1. An introducer sheath having integrated embolic protection, said introducer sheath comprising:an access sheath having a lumen with an open distal end; and
an embolic filter comprising a porous mesh material having a cylindrical outer portion and a inner portion defining a collection chamber for captured emboli, the filter having a collapsed configuration and a deployed configuration wherein the collection chamber is defined between an inner surface of the cylindrical outer portion and an outer surface of the inner portion and an outer periphery of the cylindrical outer portion of the filter is configured to contact a blood vessel wall to direct blood flow and potential emboli into the collection chamber; wherein a distal end of the inner portion of the mesh is attached to the open distal end of the access sheath and a distal end of the cylindrical outer portion of the mesh is open and free of attachment to the access sheath, wherein the lumen of the access sheath is available to introduce different devices.

US Pat. No. 10,166,093

SOFT TISSUE REPAIR PROSTHESIS AND EXPANDABLE DEVICE

C.R. Bard, Inc., Murray ...

1. A hernia repair device, comprising: an inflatable device configured to be removably connected with a soft tissue repair prosthesis, the inflatable device having a first inflatable segment and a second inflatable segment, the first inflatable segment having a first closed end such that there is no fluid communication through the first closed end, and the second inflatable segment extending past the first closed end and overlapping with a portion of the first inflatable segment over a region of overlap;wherein fluid communication between the first and second inflatable segments is closed along the entire region of overlap.

US Pat. No. 10,166,092

TOOTHBRUSH WITH A CONTROLLED TRANSMISSION DIRECTION OF VIBRATION

1. An electronic device comprising:a toothbrush head comprising a plurality of bristle touch-points arranged along rows, each of the plurality of the bristle touch-points being a single solid elongate structure extending from the toothbrush head and comprising a polymer material;
a carrying case comprising a body and a shaft, a first portion of the shaft being positioned within the toothbrush head;
electronic circuitry;
a handle comprising a handle shell surrounding the electronic circuitry, the body, and a second portion of the shaft of the carrying case, the body of the carrying case suspended within and not contacting the handle and only physically coupled at a first region to a dampener positioned between the second portion of the shaft and the handle shell, the shaft of the carrying case extending from the handle and into the toothbrush head; and
an electric motor connected to and positioned within the body of the carrying case such that the electric motor within the carrying case is suspended within the handle, the electric motor electrically coupled to the electronic circuitry and configured to generate vibration energy that is transmitted to the toothbrush head through the shaft of the carrying case to vibrate the toothbrush head.

US Pat. No. 10,166,090

DEVICE FOR DETECTING THE THREE-DIMENSIONAL GEOMETRY OF OBJECTS AND METHOD FOR THE OPERATION THEREOF

A.TRON3D GMBH, Klagenfur...

1. Method for operating a device for detecting the three-dimensional geometry of objects, especially teeth, the device comprising a handpiece that has at least one position sensor for detecting the change in the spatial position of the handpiece and an optical apparatus comprising at least one camera for taking images and at least one light source for at least one projector, comprising determining by the position sensor in the handpiece how large a change in the spatial position of the device is, and then determining how many images are taken by the camera within a defined period of time.

US Pat. No. 10,166,089

MAXILLARY PROTRACTION DEVICE

Sandra Vivian Kahn, La p...

1. A maxillary protraction device, comprising:a cranial support configured to be attached over the frontal bone of the cranium of a user;
a guide attached on a central position of the cranial support;
a vertical rod attached to said guide, wherein said vertical rod comprises an upper end configured to be attached to the guide, a central part and a lower end, wherein the central part of the vertical rod is connected to the upper end by a ratchet mechanism configured to adjust the distance of the vertical rod regarding to the user; and,
a horizontal rod attached to the lower end of the vertical rod, wherein the horizontal rod comprises gripping points configured to fix rubber bands between said horizontal rod and an orthodontic appliance of the user, being said rubber bands configured to provide a tractive force on the jaw of the user.

US Pat. No. 10,166,086

DENTAL THERAPY APPARATUS

OSAKA UNIVERSITY, Suita-...

1. A dental therapy apparatus comprising:a laser light source emitting laser light having a wavelength within a wavelength region of 5.7 to 6.6 ?m, the laser light source being a quantum cascade laser;
a controller pulse-driving the laser light source and controlling at least one of pulse width and repetition frequency of pulsed laser light emitted from the laser light source, wherein the controller switches the control of the laser light source between a first mode of driving the laser light source at a pulse width shorter than a thermal relaxation time of an area irradiated with the pulsed laser light and a repetition frequency lower than that corresponding to the thermal relaxation time and a second mode of driving the laser light source at a pulse width longer than the thermal relaxation time and a repetition frequency higher than that corresponding to the thermal relaxation time, wherein the repetition frequency for the first mode is 1 Hz to 1 kHz and the repetition frequency for the second mode is at least 1 kHz, and wherein the pulse width for cutting in the first mode is 5 ns to 1 ?s and the pulse width for the second mode is at least 1 ?s; and
an irradiation optical system for irradiating a tooth including a carious part with the light emitted from the laser light source;
wherein the controller controls at least one of the pulse width and repetition frequency of the pulsed laser light, so as to selectively cut the carious part included in the tooth.

US Pat. No. 10,166,085

METHOD OF DISINFECTING PORTS IN CENTRAL VENOUS CATHETER SYSTEMS

Hub Hygiene, Atlanta, GA...

1. A method for disinfecting a Central Venous Catheter (CVC) system port, the method comprising:scrubbing the CVC system port in a twisting motion with a formaldehyde-melamine-sodium-bisulfite foam material, wherein the foam material contains a disinfecting solution;
listening for an audible feedback resulting from a friction force between the foam material and the CVC system port; and
adjusting the friction force between the foam material and the CVC system port to produce the audible feedback.

US Pat. No. 10,166,080

COOPERATIVELY-CONTROLLED SURGICAL ROBOTIC SYSTEM WITH REDUNDANT FORCE SENSING

The Johns Hopkins Univers...

1. A cooperatively controlled robotic system, comprising:a main robot assembly comprising mechanical links connected by actuated joints;
an arm assembly comprising a proximal end and a distal end, wherein said arm assembly is connected to said main robot assembly at said proximal end;
a tool assembly connected to said arm assembly at said distal end;
a first force sensor between said distal end of said arm assembly and said tool assembly,
a second force sensor between said proximal end of said arm assembly and said main robot assembly; and
a control system in communication with said main robot assembly, said arm assembly, said tool assembly, said first force sensor, and said second force sensor,
wherein said control system is configured to determine a force applied at said first force sensor based on a force detected by said second force sensor,
wherein said control system is further configured to compare said determined force to a force detected by said first force sensor, and
wherein said control system is further configured to detect a failure of at least one of said first and second force sensors based on said comparison.

US Pat. No. 10,166,077

METHOD AND SYSTEM FOR IMAGE PROCESSING TO DETERMINE PATIENT-SPECIFIC BLOOD FLOW CHARACTERISTICS

HeartFlow, Inc., Redwood...

1. A method of image processing for non-invasive hemodynamic assessment and electronically displaying treatment planning of a stenosis in an aorta and/or a plurality of adjacent vessels, the method comprising:receiving non-invasively generated estimates of (1) patient-specific lumen anatomy of a patient's aorta and a plurality of adjacent vessels, and (2) patient-specific blood flow rates through the patient's aorta and the plurality of adjacent vessels, from non-invasively produced medical image data of the patient, wherein the aorta and/or the plurality of adjacent vessels exhibit one or more stenoses;
calculating patient-specific inlet and outlet boundary conditions for a computational model of blood flow based on the non-invasively generated estimates;
computing blood flow and pressure over the patient-specific lumen anatomy of the aorta and/or the plurality of adjacent vessels, using the computational model of blood flow and the patient-specific inlet and outlet boundary conditions, wherein computing blood flow and pressure over the patient-specific lumen anatomy of the aorta and/or the plurality of adjacent vessels includes simulating blood flow using a 3D computational fluid dynamics (CFD) simulation;
generating a reduced order patient-specific model of the computed blood flow and pressure over the patient-specific lumen anatomy of the aorta and/or the plurality of adjacent vessels;
enabling a modification of the reduced order patient-specific model to simulate treatment of the stenosis, based on the computed blood flow and pressure over the patient-specific lumen anatomy of the patient's aorta and/or the plurality of adjacent vessels; and
outputting, to an electronic storage medium or display, one or more of the reduced order patient-specific model of the computed blood flow and pressure and the modified reduced order patient-specific model simulating the treatment.

US Pat. No. 10,166,073

CONTROL DATA GENERATION FOR THE EYE-SURGICAL TREATMENT OF DEFECTIVE VISION

Carl Zeiss Meditec AG, J...

1. A method for generating control data, which are adapted to control a laser device emitting laser radiation for surgically correcting defective vision of an eye by surgically altering a shape of an optical component of the eye, the method comprising:specifying a cutting surface, which is curved, has a vertex and a border and which is to be produced in the eye by application of the laser radiation from the laser device to the optical component of the eye for correcting a defective vision;
defining at least one path curve for the control data, along which a focus of the laser radiation is to be shifted by controlling the laser device according to the control data;
selecting the at least one path curve such that at least one path curve lies in the cutting surface or within a tolerance zone around the cutting surface;
further comprising, for the selection of the at least one path curve:
defining a reference plane which is at a predetermined angle to a direction of incidence of the laser radiation and defining various shifting positions between the vertex and the border of the cutting surface for the reference plane;
defining, for each shifting position several axes or semi-axes, which lie in the reference plane, are not parallel to each other and which, when viewed in a projection along a direction of incidence, in the case of axes, intersect and in the case of semi-axes, have at least one common point;
determining, for each shifting position of the reference plane, intersection points of the axes or semi-axes with the cutting surface; and
wherein the at least one path curve is fixed in that the intersection points are connected.

US Pat. No. 10,166,070

ELECTROSURGICAL PERICARDIAL PUNCTURE

Baylis Medical Company In...

1. A method of accessing a pericardial cavity of a heart, comprising:(a) advancing a distal end of a puncture device towards the heart from a subxiphoid region of a patient wherein the distal end of the puncture device is atraumatic and comprises an energy delivery device;
(b) positioning the energy delivery device at a target site on a pericardium of the heart using ultrasound for imaging; and
(c) delivering energy from the energy delivery device to a tissue of the target site to create a channel to the pericardial cavity.

US Pat. No. 10,166,056

METHOD AND APPARATUS FOR SACROILIAC JOINT FIXATION

DePuy Synthes Products, I...

1. A bone fixation device, comprising:an elongate body, having a proximal end and a distal end;
a distal anchor on the distal end, the distal anchor defining a plurality of slits and configured to purchase with bone;
a retention structure on the elongate body, proximal to the distal anchor;
a proximal anchor, moveably carried by the elongate body;
at least one complementary retention structure on the proximal anchor configured to permit proximal movement of the elongate body with respect to the proximal anchor but to resist distal movement of the elongate body with respect the proximal anchor; and
an inner member disposed within the elongate body, the inner member comprising a distal end configured to abut the distal anchor when proximally retracted,
wherein the distal anchor is configured to flare outwardly upon proximal movement of the inner member so as to further purchase with the bone, and the outwardly flared portion of the distal anchor defines an internal space, and
wherein the inner member defines a lumen extending from a proximal end of the inner member to the distal end of the inner member, the lumen being open to the internal space when the inner member is proximally retracted.

US Pat. No. 10,166,052

BONE PLATE WITH POLYAXIAL LOCKING MECHANISM

Stryker European Holdings...

1. A bone plate comprising:a first surface and a second surface opposite to the first surface;
a deformable contact region comprising a contact surface; and
a through hole defining a through hole axis and an inner surface of the bone plate and extending from the first surface through the bone plate to the second surface,
wherein the contact surface is formed by at least part of the inner surface,
wherein the deformable contact region comprises a plurality of cavities at least partially surrounding the through hole and each substantially extending in a height direction of the bone plate, and
wherein at least one cavity of the plurality of the cavities is spaced radially from another cavity of the plurality of cavities in a direction away from the through hole axis of the bone plate.

US Pat. No. 10,166,051

BONE PLATE SYSTEM

Pioneer Surgical Technolo...

1. A bone plate system comprising:a bone plate;
a throughbore of the bone plate;
a bone anchor having an enlarged head and a shank depending therefrom, the bone anchor having a longitudinal axis extending between the head and the shank, the head including a rotary drive structure and an upwardly facing surface extending around the rotary drive structure;
a wall of the bone plate extending about the throughbore for supporting the bone anchor head in the throughbore, the bone plate wall and the bone anchor head configured to permit the bone anchor to be inserted into and extend obliquely in the throughbore with a raised portion of the upwardly facing surface of the bone anchor head at one side of the throughbore and a lowered portion of the upwardly facing surface of the bone anchor head at or adjacent an opposite side of the throughbore;
a resilient retainer disposed in the throughbore;
bone plate engaging portions of the resilient retainer secured to the bone plate at the opposite sides of the throughbore;
a pair of elongate arm portions of the resilient retainer connecting the bone plate engaging portions and extending in the throughbore spaced apart from each other, the elongate arm portions being configured to allow the raised portion of the upwardly facing surface of the bone anchor head at the one side of the throughbore to be above the bone plate engaging portion at the one side of the throughbore with the bone anchor head seated in the throughbore;
interference portions of the elongate arm portions extending in the throughbore intermediate the bone plate engaging portions and being configured to allow the interference portions to be above the lowered portion of the upwardly facing surface of the bone anchor head so that the interference portions are in interference with the lowered portion of the upwardly facing surface of the bone anchor head to resist back-out of the bone anchor from the throughbore; and
the bone anchor head and the retainer interference portions are configured so that no portion of the bone anchor head extends laterally over the retainer interference portions with the bone anchor inserted into and extending obliquely in the throughbore and the interference portions extending above the lowered portion of the upwardly facing surface of the bone anchor head.

US Pat. No. 10,166,047

INTERSPINOUS SPACER

VertiFlex, Inc., Carlsba...

1. An insertion instrument configured for delivering a spacer to an interspinous process space of a patient and deploying the spacer from an undeployed configuration to at least one deployed configuration to relieve pain; the spacer including a body, at least one arm connected to and movable with respect to the body and a spacer actuator having a proximal end and a distal end disposed at least partially inside the body that is configured to move the at least one arm from an undeployed configuration to at least one deployed configuration; the insertion instrument comprising:a handle assembly;
a first assembly connected to the handle assembly, the first assembly being configured to connect to the body of the spacer at the distal end of the insertion instrument, the first assembly having a first control at the handle assembly configured to connect and release the body of the spacer and the first assembly;
a second assembly connected to the handle assembly, the second assembly being configured to connect to the proximal end of the actuator of the spacer at the distal end of the insertion instrument, the second assembly having a second control at the handle assembly configured to connect and release the actuator and the second assembly; and
a third assembly connected to the handle assembly; the third assembly being configured to move the second assembly relative to the body of the spacer for arranging the spacer from an undeployed configuration to at least one deployed configuration.

US Pat. No. 10,166,045

ORTHOPEDIC EXTERNAL FIXATION DEVICE

Fixx Orthopedics, LLC, M...

1. A pin assembly for an orthopedic external fixation device, wherein the pin assembly is configured to engage a bone fragment, the pin assembly comprising:(i) a screw portion having a distal end configured to engage the bone fragment and a proximal end, wherein the screw portion includes an unthreaded portion between the distal end and the proximal end, and wherein the unthreaded portion includes a cutting section with one or more cutting edges; and
(ii) a support sheath portion having an elongated channel with a proximal end and a distal end, wherein the distal end of the elongated channel is configured to engage the bone fragment, wherein the proximal end of the screw portion is disposed in the elongated channel, and wherein the distal end of the elongated channel has a tapered leading edge; and
(iii) multiple elongated blades mounted to the distal end of the elongated channel such that the multiple elongated blades run lengthwise along an outer surface of the elongated channel, wherein the multiple elongated blades are configured to engage the bone fragment.

US Pat. No. 10,166,036

VARIABLE SUCTION CONTROL

Gyrus ACMI, Inc., Southb...

1. An apparatus comprising:a housing forming a handle and a shaft, the shaft extends from the handle, and the housing defines a suction channel from a distal end of the shaft and through the handle;
an electrical conductor extending from the handle through the shaft to the distal end of the shaft; and
a suction control valve connected to the suction channel at the handle, the suction control valve comprises:
a valve body having a first channel and a second channel connected to the first channel, the first channel forms a portion of the suction channel, the second channel having a recessed seat at an entrance to the second channel;
a valve barrel rotatably connected to the valve body, the valve barrel comprises a rotatable ring surrounding the valve body and forming a portion of the housing, the ring comprises an orifice configured to be rotated into and out of registration with an end of the second channel as the ring is rotated about the valve body; and
a seal configured to be aligned with the second channel at times the valve barrel is rotated to an open position and to a closed position, the seal comprising a first end and an opposite second end, the first end of the seal is received at the recessed seat, the seal comprising an opening extending from the first end of the seal to the opposite second end of the seal.

US Pat. No. 10,166,035

ENDOVASCULAR DEVICES AND METHODS FOR EXPLOITING INTRAMURAL SPACE

BRIDGEPOINT MEDICAL, INC....

1. A method of bypassing an occlusion disposed in a lumen of a vessel having a vascular wall, the method comprising:inserting a distal end of an elongate shaft of an intravascular device into the lumen proximal of the occlusion;
entering the vascular wall of the vessel with the distal end of the elongate shaft of the intravascular device at a location proximal of the occlusion;
advancing the distal end of the elongate shaft between first and second tissue layers of the vascular wall to a location distal of the occlusion;
advancing a re-entry device through the elongate shaft of the intravascular device, the re-entry device having a tissue penetrating distal tip;
penetrating the first tissue layer of the vascular wall with the tissue penetrating distal tip of the re-entry device such that the tissue-penetrating distal tip enters the lumen of the vessel distal of the occlusion; and
thereafter, advancing the distal end of the elongate shaft of the intravascular device from the vascular wall into the lumen of the vessel distal of the occlusion such that the elongate shaft of the intravascular device extends from the lumen of the vessel proximal of the occlusion, through a subintimal space between the first and second tissue layers along the occlusion, to the lumen of the vessel distal of the occlusion.

US Pat. No. 10,166,034

KNEE ARTHROPLASTY INSTRUMENT

Zimmer, Inc., Warsaw, IN...

1. A knee arthroplasty instrument for use in a knee joint, the knee joint including a tibia and a femur, the instrument comprising:a tensioning tool including a tibial component configured for placement against the tibia and a femoral component configured for placement against the femur, the femoral component being movably coupled to the tibial component to place the knee joint in tension by separating the tibia and the femur;
a first sizer removably coupleable to the tensioning tool, the first sizer including at least one first reference indicator that references the femur to locate a cut guide relative to the femur;
a second sizer different from the first sizer, used in alternative to the first sizer and removably coupleable to the tensioning tool, the second sizer including at least one second reference indicator that references the femur to locate the cut guide relative to the femur; and
a cut guide removably coupleable to the tensioning tool, wherein the femoral component of the tensioning tool and the cut guide are interchangeably coupleable to the instrument, the femoral component of the tensioning tool being separable from the instrument to accommodate the cut guide on the instrument.

US Pat. No. 10,166,033

IMPLANTS FOR BONE FIXATION OR FUSION

SI-Bone Inc., Santa Clar...

1. A method of implanting a curved implant across a joint or fracture between a first bone segment and a second bone segment, the method comprising:forming a curved insertion path from the first bone segment, across the joint or fracture between the first bone segment and the second bone segment, and to the second bone segment, wherein the curved insertion path has a predetermined radius of curvature along its length;
inserting a curved guidewire along the curved insertion path;
disposing a drill bit over the curved guidewire;
drilling a curved bore along the curved guidewire;
disposing a broach over the curved guidewire;
shaping the curved bore with the broach to form the insertion path; and
inserting a curved implant having a matching radius of curvature into the curved insertion path and into the first bone segment, across the joint or fracture, and into the second bone segment.

US Pat. No. 10,166,020

METHODS AND DEVICES FOR ACCESSING AND RETRACTING A CAPSULE OF A JOINT

Pivot Medical, Inc., Sun...

1. A method of retracting a capsule of a joint, the method comprising:forming a cut in the capsule of the joint so as to create a first flap of the capsule and a second flap of the capsule;
providing a first length of suture having a first end and a second end;
providing a second length of suture having a first end and a second end;
passing the first end of the first length of suture from the outside of the joint, through the first flap of the capsule of the joint and into the inside of the joint, and moving the first end of the first length of suture out of the joint alongside the cut in the capsule;
passing the first end of the second length of suture from the outside of the joint, through the second flap of the capsule of the joint and into the inside of the joint, and moving the first end of the second length of suture out of the joint alongside the cut in the capsule;
pulling the first and second ends of the first and second lengths of suture so as to retract the first and second flaps of the capsule of the joint;
performing an arthroscopic procedure in the joint while the capsule is retracted; and
using at least one of the first length of suture and the second length of suture to close the capsule of the joint.

US Pat. No. 10,166,018

SURGICAL RETRACTOR SYSTEM AND METHODS OF USE

NuVasive, Inc., San Dieg...

1. A surgical retractor comprising:an elongate element comprising an elongate element distal end and an elongate element proximal end with a length therebetween, the elongate element defining an operational axis along the length thereof;
a retractor handle secured to the elongate element proximal end;
a first blade having a first upper portion secured to a first arm extending from the elongate element distal end and a first blade portion comprising a first blade face;
a second blade having a second upper portion secured to a second arm extending from the elongate element and a second blade portion having a second blade face that faces the first blade face and an exterior surface opposite the second blade face, wherein the second arm is positioned along the length of the elongate element at a position between the retractor handle and the first arm, the second arm configured to move along the length of the elongate element, wherein the second blade defines a reference point located thereon, and wherein a movement of the second arm along the length of the elongate element moves the reference point in a linear direction parallel to the operational axis and orthogonal to the second blade face, wherein movement of the second arm along the length of the elongate element moves the second arm relative to the retractor handle and relative to the first arm; and
a guide element having blunt tip for insertion through muscle tissue;
wherein the second blade further comprises an opening through the second upper portion to the second exterior surface, the opening dimensioned to receive the guide element therethrough such that surgical retractor is advanceable to a surgical target site with the first blade portion and second blade portion located on the same side of the guide element.

US Pat. No. 10,166,010

SURGICAL DEVICE FOR THE COLLECTION OF SOFT TISSUE

Devicor Medical Products,...

1. A biopsy device, comprising:(a) a body;
(b) a needle extending distally from the body;
(c) a cutter movable relative to the needle configured to sever tissue;
(d) a control unit connected to the body;
(e) a display connected to the control unit, wherein the display includes one or more icons, wherein each icon is representative of at least one operational mode of a plurality of operational modes of the biopsy device, wherein each operational mode of the plurality of operational modes includes a predetermined sequence that is performed by the control unit: and
(f) at least one user input operable to control at least one operational mode of the biopsy device, wherein the at least one user input is operable to perform a secondary function of setting the control unit for particular steps during the operation of the biopsy device.

US Pat. No. 10,166,004

ULTRASOUND CONTRAST IMAGING METHOD AND APPARATUS

SHENZHEN MINDRAY BIO-MEDI...

1. An ultrasonic contrast imaging method comprising:an initial step for acquiring N frames of contrast image, wherein N is the total number of frames gathered within an imaging period;
projection imaging step for projecting the N frames of contrast image to obtain projection result image of the N frames of contrast image, wherein an nth group of original contrast image less than the N frames of contrast image is projected in a projection template to obtain a projection result image of an nth frame of original contrast image, wherein the projection template is one frame of the nth group of original contrast image, and n is a positive integer greater than or equal to 1 and less than N, wherein the nth group of original contrast images is projected within a projection period of an adjustable projection period for projecting the N frames of contrast image and comprises a plurality of frames of original contrast images including the nth original contrast image, and wherein the projection period is a value less than the imaging period of gathering the N total number of frames that is set from the adjustable projection period for projecting the N frames of contrast image once the value is designated from the adjustable projection period; and
a display and/or storage step for displaying or storing the projection result image of the N frames of original contrast image.

US Pat. No. 10,166,003

ULTRASOUND IMAGING WITH VARIABLE LINE DENSITY

VOLCANO CORPORATION, San...

1. A method for intravascular imaging, the method comprising:introducing an ultrasonic transducer into a vessel, the transducer being disposed at a distal portion of a catheter;
using a module operably coupled to a proximal portion of the catheter to provide a number of trigger signals per rotation of the ultrasonic transducer, the module comprising a rotary encoder comprising hardware steps configured to define the number of trigger signals;
rotating the ultrasonic transducer at least one rotation; and
triggering a first sequencer operation and a second sequencer operation with each trigger signal,
wherein the first sequencer operation and the second sequencer operation each comprise stimulating the ultrasonic transducer to transmit an ultrasonic signal into the vessel;
wherein at least the second sequencer operation comprises receiving a backscattered ultrasound signal from the vessel with the ultrasonic transducer.

US Pat. No. 10,166,001

TRENDING S1 HEART SOUNDS AMPLITUDES IN AMBULATORY PATIENTS FOR WORSENING HF DETECTION

Cardiac Pacemakers, Inc.,...

1. An apparatus comprising:a cardiac signal sensing circuit configured to sense a plurality of cardiac signals representative of electrical cardiac activity of a subject;
a heart sound sensing circuit configured to sense a plurality of heart sound signals representative of intrinsic mechanical cardiac activity of the subject; and
a signal processing circuit configured to:
detect a signal fiducial in a sensed cardiac signal and initiate a measurement window in a time relationship to the detected fiducial;
determine amplitudes of S1 heart sounds during the measurement window using the plurality of sensed heart sound signals;
calculate a short-term central tendency of the S1 heart sound amplitudes over a time duration of N days, where N is a positive integer less than or equal to five:
calculate a long-term central tendency of the S1 heart sound amplitudes for a time duration longer than N days, during different days than the short-term central tendency, and at least partially prior to the short-term central tendency;
trend a long-term to short-term difference between the calculated long-term central tendency of the S1 heart sound amplitudes and the calculated short-term central tendency of the S1 heart sound amplitudes; and
generate an alert using the calculated short-term central tendency and the calculated long-term central tendency.

US Pat. No. 10,165,993

X-RAY IMAGIN DEVICE WITH DISTRIBUTED X-RAY SOURCE

VATECH Co., Ltd., Gyeong...

1. An X-ray radiography device, the device comprising:an X-ray source including a plurality of X-ray emitting elements arranged in an at least 2×2 pixel matrix and respectively emitting X-rays to a target; and
an X-ray detector detecting the X-rays transmitted through the target
wherein one of the X-ray source and the X-ray detector has a curved surface surrounding the target,
wherein the X-ray detector includes a plurality of X-ray detecting elements arranged in an at least 2×2 pixel matrix on a planar surface or a curved surface to be mapped one-to-one or one-to-many to the X-ray emitting elements, and respectively to detect each of the X-rays transmitted through the target,
wherein the plurality of X-ray emitting elements and the plurality of X-ray detecting elements are arranged on separate planar surfaces or on separate curved surfaces, and
wherein the X-ray radiography device comprise a flexible bending part connecting the separate planar surfaces or the separate curved surfaces to each other.

US Pat. No. 10,165,992

X-RAY IMAGING SYSTEMS AND DEVICES

Carestream Health, Inc., ...

1. An x-ray tube head comprising:a plurality of cold cathode radiation sources for emitting x-rays when energized by an electric current; and
an enabling circuit configured to selectively enable and disable any of a first subset of the cold cathode radiation sources to be switchably connected to a source of the electric current, and to selectively enable and disable any of a second redundant subset of the radiation sources to be switchably connected to the source of electric current;
a detection circuit configured to detect whether any of the enabled radiation sources in the first subset is inoperable; and
a switch circuit for switchably connecting selected ones of the enabled radiation sources in the second subset to the source of electric current.

US Pat. No. 10,165,986

RECEIVERS FOR ANALYZING AND DISPLAYING SENSOR DATA

DexCom, Inc., San Diego,...

1. A glucose monitoring system for monitoring a host's glucose levels, the system comprising a computing device having a touch-sensitive display, wherein the computing device is configured to:display on the touch-sensitive display a first chart and a second chart adjacent to one another, each chart having a trend line indicative of a glucose level of a host, each chart having a y-axis in units of an analyte concentration and an x-axis in units of time, and each x-axis of the first and second charts extending different periods of time, wherein the x-axis of the first chart extends a first period of time and the x-axis of the second chart extends a second period of time, the first period of time being a sub-set of the second period of time, wherein the second chart comprises a first indication of the first time period, wherein the first indication comprises a shaded pattern under the trend line of the second chart, wherein the second chart comprises a second indication of the first time period, wherein the second indication of the first time period comprises an icon extending along the y-axis of the second chart, wherein the icon moves along the x-axis of the second chart responsive to a user changing the first time period; and
wherein the time period of the second chart changes from the second time period to a third time period when the icon moves to a certain time value of the second time period, the second time period being a sub-set of the third time period.

US Pat. No. 10,165,967

SYSTEMS AND METHODS FOR A CONTINUOUS MONITORING OF ANALYTE VALUES

DexCom, Inc., San Diego,...

1. A method for wireless data communication among an analyte sensor system, a passive device for receiving data from a transceiver without establishing a data connection with the analyte sensor system, and an active display device for displaying analyte data from the analyte sensor system after establishing a data connection with the analyte sensor system, the method comprising:generating analyte sensor data using a sensor electronics module coupled to a continuous analyte sensor of the analyte sensor system;
incorporating in a first advertisement signal the analyte sensor data that can be used by the passive device;
a user providing the passive device with an identification information associated with the analyte sensor system;
the passive device generating a key using the identification information;
upon receiving the first advertisement signal from the analyte sensor system, extracting the analyte sensor data by the passive device from the first advertisement signal, to perform one or more medicament delivery operations based on an analyte value that is indicated by the extracted analyte sensor data, wherein the passive device extracts the analyte sensor data from the first advertisement signal using the key generated from the identification information associated with the analyte sensor system;
receiving, by the active display device, a second advertisement signal, wherein the analyte sensor system is configured to include the analyte sensor data in the second advertisement signal;
establishing a two-way communication channel by the active display device with the analyte sensor system in response to the second advertisement signal;
exchanging information including the analyte sensor data, alarms, alert and calibration data between the active display device and the analyte sensor system via the established communication channel;
terminating the communication channel; and
displaying the analyte sensor data by the active display device.

US Pat. No. 10,165,966

METHODS AND SYSTEMS FOR MONITORING RESISTANCE AND WORK OF BREATHING FOR VENTILATOR-DEPENDENT PATIENTS

University of Florida Res...

1. A method comprising:(a) non-invasively measuring pressure and flow data from a breathing circuit of an intubated patient;
(b) using the pressure and flow data from step (a), determining endotracheal pressure without an end-inspiratory pause and an end-expiratory pause; and
(c) using the endotracheal pressure determined from step (b), calculating estimated real-time airway resistance (RAW), endotracheal tube resistance (RETT), and total resistance (RTOT) values, wherein the estimated RAW value is calculated based on the estimated RETT and RTOT values, and wherein the pressure and flow data include pressure measured at a wye-piece of the breathing circuit, pressure measured at a distal end of an endotracheal tube, and airway flow within the breathing circuit, wherein the RETT value is calculated based on a difference in tracheal airway pressure and pressure measured at the wye-piece, and dividing the difference by flow rate;
determining whether the estimated RAW value or the estimated RETT value is outside a predetermined RAW range or RETT range, respectively; and
determining based upon the determination of whether the estimated RAW value or the estimated RETT value is outside the predetermined RAW range or the predetermined RETT range, respectively i) whether to administer bronchodilator therapy, ii) whether the endotracheal tube is obstructed, iii) whether to titrate bronchodilator treatment, (iv) how to titrate bronchodilator treatment, v) whether to titrate ventilatory support, or vi) how to titrate ventilator support.

US Pat. No. 10,165,957

NEUROLOGICAL SCREENING CONNECTOR

MEDTRONIC, INC., Minneap...

1. A medical lead screening connector comprising:a housing having a top surface;
lead receptor channels disposed within the housing and configured to receive a lead body flush or sub-flush with the top surface; and
a cover comprising transparent material attached to the housing to cover the top surface in a closed position, wherein the cover further comprises:
protrusions arranged to register with the at least one of the lead receptor channels and each configured to contact the lead body received in the respective lead receptor channel in the closed position; and
lead receptor apertures configured to allow the lead body to pass through the cover along a first exterior edge of the cover and registered with the lead receptor channels in the closed position.

US Pat. No. 10,165,953

METHODS AND SYSTEMS FOR RECALIBRATING A BLOOD PRESSURE MONITOR WITH MEMORY

Nellcor Puritan Bennett I...

1. A method for triggering a cuff-based blood pressure measurement of a subject, the method comprising:receiving a photoplethysmograph (PPG) signal from a sensor;
monitoring, using a processor, a first value of a metric derived at least in part from the PPG signal;
comparing, using the processor, the first value of the metric to each stored value of a plurality of stored values, wherein each stored value of the plurality of stored values is associated with a respective calibration parameter;
determining, using the processor, that the first value of the metric does not correspond to any stored value of the plurality of stored values based at least in part on the comparison;
triggering, using the processor, the cuff-based blood pressure measurement in response to determining that the first value of the metric does not correspond to any stored value of the plurality of stored values;
executing, using an inflatable cuff, the cuff-based blood pressure measurement of the subject in response to the trigger;
determining, using the processor, a second value of the metric;
comparing, using the processor, the second value of the metric to stored values of the plurality of stored values;
determining, using the processor, that the second value of the metric corresponds to a stored value of the plurality of stored values based at least in part on the comparison; and
recalling, from at least one memory device, a set of blood pressure calibration parameters associated with the stored value of the plurality of stored values based on determining that the second value of the metric corresponds to the stored value.

US Pat. No. 10,165,952

BIOLOGICAL INFORMATION MEASURING APPARATUS AND BIOLOGICAL INFORMATION MEASURING METHOD

NIHON KOHDEN CORPORATION,...

1. A biological information measuring apparatus comprising:a pulsation information detecting unit configured to detect heartbeat information relating to a heartbeat of a subject;
a pulse wave detecting unit configured to detect a pulse wave of the subject during a time period in which a cuff is inflated to pressurize a portion of the subject and during a time period in which the cuff is deflated to depressurize the portion of the subject;
an amplitude calculating unit configured to detect a cardiac cycle of a heart from the heartbeat information and a maximal value of the pulse wave in each cardiac cycle, and to calculate, based on the maximal value detected from the pulse wave, at least one of an amplitude value derived from the heartbeat of the subject, an amplitude value assisted by an intra-aortic balloon pump (IABP), and an amplitude value derived from a blood flow volume of the subject; and
a blood pressure calculating unit configured to calculate a blood pressure value from a relationship between the at least one of the amplitude value derived from the heartbeat of the subject, the amplitude value assisted by the IABP, and the amplitude value derived from a blood flow volume of the subject calculated by the amplitude calculating unit and a pressurizing force of the cuff.

US Pat. No. 10,165,930

ENDOSCOPE

FUJIFILM Corporation, To...

1. An endoscope comprising:an insertion portion which includes a distal end and a proximal end;
an operation portion which is provided on a proximal end side of the insertion portion and includes an operating member;
a distal end portion body which is provided on a distal end side of the insertion portion;
a rotating shaft which is rotatably supported in the distal end portion body;
an elevator which is coupled with one end of the rotating shaft;
an elevator erecting lever which is coupled with the other end of the rotating shaft;
an operating wire which includes a proximal-end-side coupling portion coupled with the operating member and a distal-end-side coupling portion coupled with the elevator erecting lever, the operating wire configured to rotate the rotating shaft through the elevator erecting lever by operation of the operating member to erect the elevator;
a partition wall which includes a holding hole to support the rotating shaft, is a part of the distal end portion body and is provided between the elevator and the elevator erecting lever; and
a seal member which is disposed between the holding hole and the rotating shaft, wherein:
the rotating shaft includes a first rotating shaft and a second rotating shaft;
the first rotating shaft has one end connected with the elevator erecting lever and another end provided with a first coupling portion;
the second rotating shaft has one end that is integrally formed with the elevator or connected with the elevator by welding of the one end and the elevator, and another end provided with a second coupling portion which is coupled with the first coupling portion in a relativity unrotatable manner; and
a coupling position in which the first coupling portion and the second coupling portion are coupled with each other is disposed on a side of the elevator erecting lever with respect to the seal member.

US Pat. No. 10,165,929

COMPACT MULTI-VIEWING ELEMENT ENDOSCOPE SYSTEM

EndoChoice, Inc., Alphar...

1. A manifold for use in an endoscope, comprising:a manifold housing having a partially cylindrical shape with a curved top surface, a partially curved first side and a partially curved second side wherein the manifold housing comprises a base, wherein the base has a first width, a first length, and a proximal surface, and an elongated portion, which is attached to the base, wherein the elongated portion has a second width, a second length, and a distal surface, wherein the first width is greater than the second width and the first length is less than the second length; and
a Y-shaped fluid conduit comprising a central stem portion, a first prong portion, and a second prong portion, wherein the central stem portion extends from an entrance port on the proximal surface of the base through the base, wherein the first prong portion extends from a distal end of the central portion through the base to an exit port on the partially curved first side, and wherein the second prong portion extends from the distal end of the central portion through the base to an exit port on the partially curved second side.

US Pat. No. 10,165,924

WATER TANK WASHING MACHINE

Ningbo Fotile Kitchen War...

1. A sink-type washing machine comprising:a sink body having a washing space and a bottom portion, the sink body having a recess, the recess defining a drain region at least at a center of the bottom portion, the bottom portion of the sink body comprises a bottom board, the recess is formed at a center of the bottom board;
an ultrasonic generator disposed on the bottom board;
a water pump disposed inside the drain region for pumping water in the drain region, the water pump having a flow channel and an impeller;
a cover plate rotatably connected on the sink body;
a drain board with a plurality of drain holes disposed inside the sink body and covering the recess of the bottom board, the recess under the drain board forming the drain region;
a rotary spray arm with a plurality of water outlets disposed above the drain board, the plurality of water outlets being in communication with the flow channel in the water pump,
wherein the water in the drain region can be sprayed into the washing space and above the drain region,
the impeller further comprises a central shaft and a plurality of blades disposed on a circumferential surface of the central shaft, each blade having a curvy part and a straight part, the straight part extending axially away from the central shaft, and
the drain board further defines a circular opening and a residue basket is disposed in the sink body, under the circular opening and flushed with the drain board, and a surface of the drain board is flushed with the bottom board of the sink body around the drain board.

US Pat. No. 10,165,922

APPARATUS AND METHOD FOR DETECTING MATERIALS

1. A nozzle comprising a first light and a second light, wherein the first light is a white light and the second light is other than a white light,the nozzle further comprising a squeeze trigger, and wherein activation of the trigger activates at least one of the first and second lights,
wherein activation further comprises a partial activation by partially depressing the squeeze trigger and a full activation by fully depressing the squeeze trigger, and
wherein one of the first and second lights is activated during partial activation of the squeeze trigger.

US Pat. No. 10,165,919

VACUUM BAG

SHOP VAC CORPORATION, Wi...

1. A vacuum cleaner bag assembly adapted to be removably disposed within a vacuum cleaner, the vacuum cleaner bag assembly comprising:a panel assembly comprising a first panel and a second panel forming an enclosure having an interior volume, wherein an aperture extends through the first panel, the aperture adapted to receive debris exiting an outlet end of a hose assembly such that the debris is retained within the interior volume, each of the first panel and the second panel including an outer sheet and a liner sheet, wherein each of the outer sheets comprises a first outer material and each of the liner sheets comprises a first liner material; and
a shield member disposed within the interior volume and secured to one or more portions of the panel assembly, wherein the shield member comprises a second non-porous and non-absorbent flexible material that is different than each of the first outer material and the first liner material, the shield member extends vertically from a first point at or adjacent to a top portion of the panel assembly to a second point vertically disposed between a bottom portion of the aperture and a bottom portion of the panel assembly, wherein the shield member includes a first portion and a second portion, the shield member being folded about a transverse axis that is disposed at or adjacent to the first point at or adjacent to the top portion of the panel assembly such that during normal operation the first portion of the shield member abuts and applies a biasing force to the first panel of the panel assembly, the shield member is disposed opposite the aperture on the second panel and directly exposed to the aperture when the vacuum cleaner bag assembly is disposed within the tank such that the shield member protects a corresponding portion of the panel assembly from being impacted by debris passing through the aperture and into the interior volume and directly into contact with the shield member.

US Pat. No. 10,165,917

CLEANOUT TOOL FOR A SURFACE CLEANING APPARATUS

BISSELL Homecare, Inc., ...

1. A cleanout tool for an extraction cleaner having a fluid delivery system for delivering cleaning fluid to a surface to be cleaned, and a recovery system for removing spent cleaning fluid and debris from the surface to be cleaned and comprising a suction nozzle defining a suction pathway, a suction source in fluid communication with the suction nozzle for generating a working air stream and an agitator provided adjacent to the suction nozzle for agitating the surface to be cleaned, the cleanout tool comprising:an elongated body having a first end and a second end opposite the first end and wherein the body is flat and rectilinear in shape, with two opposing sides and joined with two opposing edges which are more narrow than a width defined by the sides;
the first end of the body, defined by one of the opposing edges, comprising at least one hook; and
the second end of the body, defined by another of the opposing edges, comprising a comb disposed at an angle relative to the elongated body, wherein the comb comprises a plurality of tines and the plurality of tines have ends which define an angled edge of the second end;
wherein the first end of the body is configured to be inserted into the suction nozzle to remove material within the suction nozzle using the at least one hook to catch the material;
wherein the second end of the body is configured to remove material from the agitator using the comb; and
wherein the at least one hook and the plurality of tines lie in a common plane.

US Pat. No. 10,165,916

VACUUM CLEANER BASE ASSEMBLY AND AIR PASSAGE SYSTEM

MIDEA AMERICA, CORP., Pa...

1. A vacuum cleaner comprising:a handle having a first handle side and a second handle side opposite the first handle side;
a dirt separator mounted to the handle and having a separator inlet for receiving dirt-laden air and a separator outlet for discharging cleaned air;
a suction motor mounted in the handle and having a suction motor inlet, the suction motor being configured to generate a suction airflow into the suction motor inlet;
a nozzle having a bottom face, a first side region that extends along the first handle side, and a second side region that extends along the second handle side to thereby locate at least a portion of the handle between the first side region and the second side region;
a suction inlet passing through the bottom face of the nozzle, the suction inlet comprising an opening that is elongated along a suction inlet axis extending from the first side region to the second side region;
a pivot joining the nozzle to the handle at a pivot axis that extends from the first side region of the nozzle to the second side region of the nozzle and in parallel with the suction inlet axis, the pivot comprising a first pivot connection joining the first side region to the first handle side, and a second pivot connection joining the second side region to the second handle side;
wherein the nozzle comprises an upper shell and a lower shell that are joined together, the upper shell comprising an upper arm having a lower surface, the lower shell comprising a lower arm having an upper surface, wherein the lower surface of the upper arm faces the upper surface of the lower arm and the lower surface and the upper surface are connected at respective edges thereof to form an enclosed rigid base air passage extending from the suction inlet to the first pivot connection;
a first handle air passage located in the handle and extending from the first pivot connection to the separator inlet, the first handle air passage being fluidly connected to the base air passage through the first pivot connection;
a second handle air passage located in the handle and extending from the separator outlet to the suction motor inlet;
a carriage mounted to the nozzle and the handle to rotate relative to the nozzle and the handle, the carriage being configured to support the nozzle and the handle on a horizontal plane the carriage comprising a first side region adjacent to the first side region of the nozzle and a second side region adjacent to the second side region of the nozzle; and
a storage lock assembly comprising a resiliently-deformable crossbeam and a protrusion,
wherein the crossbeam comprising at least a portion that is substantially linear in shape and longitudinally extending between the first side region of the carriage and a second side region of the carriage, the portion of the crossbeam being deformable from the substantially linear shape, and the protrusion comprises an extension of the handle and rotates with the handle, the protrusion presses against and temporarily deforms the crossbeam when the handle is moved from an upright position to a reclined position or from the reclined position to the upright position.

US Pat. No. 10,165,910

WATERLESS TOILET SYSTEM

Convergent Market Researc...

1. A toilet system including:(a) a support structure;
(b) a transport conduit mounted on the support structure, the transport conduit including a discharge end, an inner end, and a commode opening located between the discharge end and inner end;
(c) a flush member positioned within the transport conduit and being movable between a retracted position and an extended position, wherein in the retracted position a sealing end of the flush member resides between the commode opening and the inner end of the transport conduit and in the extended position the sealing end of the flush member resides approximately at the discharge end of the transport conduit;
(d) an outer seal element mounted on the support structure and being movable between a sealing position and a displaced position, wherein in the sealing position the outer seal element seals the discharge end of the transport conduit and in the displaced position the outer seal element is separated from the discharge end of the transport conduit; and
(e) an actuator system mounted on the support structure and operatively connected to the flush member, the actuator system including a member providing a mechanical connection to the outer seal element and being operable in response to a drive force applied through a drive mechanism to move the flush member and the outer seal element in a flush cycle in which (i) at least a discharge gap is maintained between the flush member and the outer seal element as the flush member moves from the retracted position to the extended position and the outer seal element moves from the sealing position to the displaced position, and (ii) the flush member then moves back to the retracted position and the outer seal element moves back to the sealing position.

US Pat. No. 10,165,908

HAND DRYER WITH REDUCED AIR-INTAKE NOISE

HOKWANG INDUSTRIES CO., L...

1. A hand dryer with reduced air-intake noise, comprising:a housing, including an accommodating space and a plurality of narrow air inlets connecting the accommodating space and an outside of the housing, and the housing defines an air intake surface that faces the accommodating space and on which the plurality of narrow air inlets are provided;
a flow-guide plate disposed inside the accommodating space and assembled, corresponding to the air intake surface with the housing, the flow-guide plate being not in contact with the air intake surface, and the flow-guide plate including a plurality of narrow air guide holes; and
an air supply module disposed inside the accommodating space, comprising a blower that extracts the air inside the accommodating space to generate a drying air flow after being started and an air-guide piece that is connected to the blower to receive the drying air flow and includes an end exposed from the housing; and
wherein the hand dryer includes an air intake path that enables, after the blower is started, the air sequentially flows from the outside of the housing to enter the blower through the plurality of narrow air inlets and the plurality of narrow air guide holes.

US Pat. No. 10,165,904

HIDDEN SHOWER SURROUND STORAGE

DELTA FAUCET COMPANY, In...

1. A shower surround wall comprising:a molded planar wall member for attaching directly to a structure wall and in parallel thereto;
an opposing wall facing opposite said molded planar wall member, said opposing wall for attaching directly to another structure wall and in parallel thereto;
at least one shelf extending away from said molded planar wall member and toward said opposing wall, said shelf having a shelf end most distal from said molded planar wall member, and wherein said at least one shelf is open to a direction facing into the shower surround wall, and wherein said at least one shelf extends only partially across a width of said molded planar wall member;
a forward wall extending away from said molded planar wall member and toward said opposing wall, said forward wall having a top, said top having a first inner end, and a bottom having a second inner end, said first and second inner ends facing into said shower surround wall, and an inner edge extending linearly along a length between said first inner end and said second inner end, said inner edge extending from said molded planar wall member for a distance that is at least as far as said shelf end and positioned on a side of said at least one shelf wherein the forward wall faces toward a location outside of said shower surround wall when said molded planar wall member is mounted to the structure wall, such that said forward wall at least partially blocks a sight line to said at least one shelf; and
a rear wall configured to extend between said molded planar wall member and said opposing wall, said rear wall extending perpendicular to said molded planar wall member and said opposing wall, and wherein said shelf end is parallel to said molded planar wall member and said opposing wall.

US Pat. No. 10,165,887

COOKING DEVICE UTILIZING INGREDIENT CARTRIDGE ASSEMBLY

Foodstar LLC, Jericho, N...

1. A cooking device effective to utilize an ingredient cartridge assembly, the cooking device comprising:a cooking pot;
a heat source;
a cartridge loading track;
a cartridge propulsion system;
an ingredient loading compartment located along the cartridge loading track;
a gear motor;
a mixing blade within the cooking pot, wherein the gear motor powers the mixing blade;
a stirrer;
a mixing fork within the cooking pot, wherein the stirrer powers the mixing fork; and
a controller in communication with the heat source, the cartridge propulsion system, the gear motor, and the stirrer;
wherein the cartridge propulsion system is configured to:
receive an ingredient cartridge assembly including a cartridge, wherein a protective film on the cartridge is contacted with the cartridge propulsion system; and
turn and pull the protective film to peel off the protective film from the cartridge and to slide the cartridge along the cartridge loading track towards the ingredient loading compartment so that an ingredient inside of the cartridge deposits into the ingredient loading compartment as the cartridge passes over the ingredient loading compartment, wherein the ingredient loading compartment is configured to deposit the ingredient into the cooking pot.

US Pat. No. 10,165,877

STACKABLE CONTAINER SYSTEM

Runway Blue, LLC, Alpine...

1. A stackable container system comprising:a beverage container comprising:
a beverage container body;
a beverage container lid connecting portion disposed at least proximate an upper portion of the beverage container body, the beverage container lid connecting portion comprising a threaded connecting portion disposed on an outer surface of the upper portion of the beverage container body;
an annular flange extending downwardly from a lower portion of the beverage container body; and
a smaller container lid connecting portion disposed on an interior wall of the annular flange, the smaller container lid connecting portion comprising a male portion of a bayonet mount including an inwardly extending flange from the annular flange and an engaging portion;
a beverage container lid selectively connected to the beverage container lid connecting portion of the beverage container, the beverage container lid comprising an opening and a closure, the closure sized and configured to selectively close the opening in the lid, the beverage container lid including a threaded connecting portion disposed on an inner surface of an annular wall;
at least one smaller container sized and configured to be selectively connected to the beverage container, each smaller container comprising:
a smaller container body; and
a threaded connecting portion disposed at least proximate an upper portion of the smaller container body, the threaded connecting portion disposed on an outer surface of the upper portion of the smaller container body; and
at least one smaller container lid sized and configured to be selectively connected to the threaded connecting portion of the smaller container and the smaller container lid connecting portion of the beverage container, each smaller container lid comprising:
a first connecting structure on a first side of the smaller container lid, the first connecting structure comprising a threaded connecting portion on an inner surface of a downwardly extending flange that is selectively connected to the threaded connecting portion of the smaller container;
a second connecting structure on a second side of the smaller container lid, the second connecting structure comprising a female portion of a bayonet mount, the female portion of the bayonet mount comprising:
an upwardly extending portion having a perimeter located horizontally inward of a perimeter of the downwardly extending flange of the first connecting structure on the first side of the smaller container lid;
at least one outwardly extending flange disposed on an outer wall of the upwardly extending portion, an upper surface of the outwardly extending flange generally aligned with an upper surface of the upwardly extending portion of the second connecting structure; and
an upwardly extending receiving portion disposed in a lower portion of the outwardly extending flange, the upwardly extending receiving portion sized and configured to receive the engaging portion of the smaller container lid connecting portion when the smaller container lid is connected to the smaller container lid connecting portion of the beverage container; and
a central portion disposed between and separating the first connecting structure and the second connecting structure of the smaller container lid, the first connecting structure and the second connecting structure comprising different types of connecting structures;
wherein the outwardly extending flange of the second connecting structure of the smaller container lid at least partially abuts the inwardly extending flange of the smaller container lid connecting portion of the beverage container when the smaller container lid is connected to the beverage container;
wherein the second connecting structure of the smaller container lid is at least partially disposed in the smaller container lid connecting portion of the beverage container when the smaller container lid is connected to the beverage container; and
wherein the threaded connecting portion of the smaller container is at least partially disposed in the first connecting structure of the smaller container lid when the smaller container is connected to the smaller container lid.

US Pat. No. 10,165,874

BAGGING STATION BAGGING CLIP

WALMART APOLLO, LLC, Ben...

1. A shopping bag bagging station comprising:a bag holder comprising a bag holder hook; and
a bagging clip coupled to the bag holder hook, wherein the bagging clip comprises:
a plate;
a first slot and a second slot in the plate; and
a center support defined by the first and the second slot, wherein each of the first and the second slot form an opening on an edge of the plate, and wherein the first slot and the second slot couple the plate to the bag holder hook.

US Pat. No. 10,165,872

PANEL ASSEMBLY, PANEL SYSTEM INCLUDING THE PANEL ASSEMBLY, AND METHOD THEREOF

THINKTERIOR STUDIO PTE. L...

1. A panel assembly configured to be hangable on a hanging horizontal beam mounted to a structural support and usable with at least one peg to display an object, the panel assembly comprising:a first panel having a front side and a back side, and a plurality of spaced first through holes extending between the front side and the back side; and
a first back support having a first side and a second side opposite the first side thereof, and secured to the first panel, with the first side of the first back support confronting the back side of the first panel,
wherein the first back support includes, on the first side thereof, a plurality of first blind holes that each align with one of the plurality of spaced first through holes,
wherein the first back support is configured to engage and hang from the hanging horizontal beam,
wherein each of the plurality of spaced first through holes is dimensioned to permit one of the at least one peg to pass therethrough,
wherein each of the plurality of first blind holes is dimensioned to receive one of the at least one peg inserted through one of the plurality of spaced first through holes, and
wherein the first back support comprises:
a plurality of first vertical beams each having a first side disposed confronting the back side of the first panel and a second side opposite the first side thereof, the plurality of first vertical beams being horizontally spaced from each other; and
a first horizontal beam having a first side disposed confronting the back side of the first panel and a second side opposite the first side thereof,
wherein each of the plurality of first vertical beams has, on the first side thereof, a first slot sized to receive the first horizontal beam and allow the first side of the first horizontal beam and the first sides of the plurality of first vertical beams to contact the back side of the first panel, and
wherein each of the plurality of first vertical beams has a plurality of vertically spaced first blind holes opening from the first side thereof, the plurality of first blind holes in the first back support comprising the plurality of vertically spaced first blind holes in the plurality of first vertical beams.

US Pat. No. 10,165,870

DISPLAY CASE DOOR ASSEMBLY WITH VACUUM PANEL

Anthony, Inc., Sylmar, C...

1. A display case door assembly for a temperature-controlled storage device, the display case door assembly comprising:a frame defining an opening into the temperature-controlled storage device; and
a transparent unit coupled to the frame, the transparent unit comprising:
a first vacuum pane,
a second vacuum pane,
an evacuated gap between the first and second vacuum panes, the evacuated gap having a predetermined thickness within which a vacuum is drawn, thereby providing a thermal insulation effect for the transparent unit,
a plurality of spacers disposed within the evacuated gap and configured to maintain the predetermined thickness of the evacuated gap with the vacuum drawn therein,
an additional glass pane laminated to one of the first vacuum pane or the second vacuum pane, the additional glass pane being made of tempered glass, and
a handle attached to a front surface of the additional glass pane without penetrating the additional glass pane, the handle arranged to extend away from the temperature-controlled storage device,
wherein at least one of the first vacuum pane and the second vacuum pane is made of non-tempered glass.

US Pat. No. 10,165,861

CHAIR ASSEMBLY WITH UPHOLSTERY COVERING

Steelcase Inc., Grand Ra...

1. A seating unit component assembly, comprising:a support component adapted to support a portion of a seated user, the support component including a first surface adapted to abut a seated user, a second surface opposite the first surface, a first end surface, a second end surface opposite the first end surface, and a pair of side surfaces extending between the first and second end surfaces; and
a cover having a plurality of sides that cooperate to form an interior space that receives the support component therein, the cover comprising:a first portion comprising a substantially flexible, elastically resilient material covering at least a portion of at least one of the side surfaces of the support component;a second portion comprising a significantly flexible material having a flexibility that is greater than the flexibility of the first portion and covering at least a portion of the first surface and at least a portion of the first end surface of the support component; anda third portion comprising a substantially rigid overlay, wherein the third portion is less flexible than the first portion, and wherein the third portion covers at least a portion of the second surface and at least a portion of the side surfaces of the support component.

US Pat. No. 10,165,857

ROLLER UNIT HAVING INTEGRATED FASTENING PORTION

SEGOS CO., LTD., Incheon...

1. A roller unit comprising:a supporting shaft comprising:
a first flange formed on the fastening portion;
a second flange formed on the first flange and having an outer diameter larger than an outer diameter of the first flange;
a fastening portion formed in a downward direction below the first flange; and
a supporting portion formed on the second flange in an upward direction opposite to the fastening portion;
a rotating body rotatably coupled to the supporting shaft and having a fixing groove recessed in the upward direction and a hollow portion in a center of the rotating body through which the supporting portion is inserted; and
a washer on which the rolling body and the second flange seat, the washer having an insertion protrusion protruding in the upward direction and fitted in the fixing groove to be coupled with the rolling body, thereby preventing separation of the supporting shaft and the rotating body by retaining the supporting shaft and the rotating body.

US Pat. No. 10,165,855

STORAGE RACK

Seville Classics, Inc., ...

1. A method of deploying a rack assembly, comprising:providing a rack comprising:
(i) a frame having a left support, and a right support
(ii) a plurality of shelves, each shelf having:
an enclosing frame member that has two opposing first sides connected by two opposing second sides, with each second side having an interior defined by a first surface and a second surface that is opposite to the first surface, wherein each second side has a planar top surface and a planar bottom surface, and wherein the second surface, the planar top surface and the planar bottom surface are formed in one piece;
at least one slot provided on each of the first surfaces of the second sides, each slot defining an opening located entirely between the planar top surface and the planar bottom surface of the corresponding second side; and
a plurality of separate elongated slats, each slat having a length that is greater than its width, each slat having a plurality of outer surfaces that encircle a cross-section so that the cross-section of each slat is retained inside a slot of the at least one slot, each slat having opposing ends that are positioned at opposing slots at the second sides in a manner such that each end of each slat is retained inside the interior of a corresponding second side, with the second surface completely covering the interior so that the ends of the slats are not visible from outside the second surface; wherein the plurality of outer surfaces of each slat includes two parallel vertical outer surfaces;
connecting one second side of a shelf to the left support; and
connecting the other second side of the shelf to the right support.

US Pat. No. 10,165,845

TOOL PACK SYSTEM WITH REMOVABLE TOOL PANELS

Ty-Flot, Inc., Mancheste...

1. A backpack system adapted for carrying hand tools comprising:a backpack having a front, a back, a first side, a second side, a top portion, and a bottom portion, the backpack comprising:
a base having a bottom panel on the bottom portion of the backpack, a front base, a rear base, and a sidewall extending along at least part of a perimeter of the bottom panel and extending upward from the bottom panel;
a first shell portion secured to the rear base and defining a back panel configured to abut an user's back;
a second shell portion secured to the front base and aligned with and opposing the first shell portion;
a releasable closure connected between the first shell portion and the second portion, wherein the backpack is operable between an open position and a closed position and in the closed position defines and encloses a main storage compartment;
a pair of shoulder straps each attached to and extending between the base and the top portion of the backpack;
a rigid floor spaced vertically above the bottom panel and having a front floor margin connected along the front base and extending upward to a rear floor margin connected to and extending across the back panel;
at least one tool panel with one or more tool receivers each constructed to retain a hand tool, the at least one tool panel having a tool panel side portion and a tool panel lower end portion, wherein the at least one tool panel is sized to be disposed within the main storage compartment;
a panel-retaining structure with a first retaining portion on the tool panel lower end portion and a second retaining portion secured to the rigid floor, wherein the first retaining portion and the second retaining portion releasably interlock to retain the at least one tool panel in the main storage compartment; and
a tether extending between a first end portion and a second end portion with closed-loop connector, wherein the first end portion is secured to the base and the tether is secured to and extends upward along the back panel of the first shell and exits from a tether opening on one of the pair of shoulder straps.

US Pat. No. 10,165,838

PROTECTIVE COVER FOR A MOBILE DISPLAY DEVICE

Logitech Europe S.A., Lu...

1. A protective cover for a mobile display device comprising:a housing including:
an outer portion having a generally rectangular frame structure configured to, when the protective cover is coupled to a mobile display device, provide a protective shell along an edge perimeter surrounding a display of the mobile display device; and
an inner portion coupled to the outer portion and constructed of a deformable material,
wherein the inner portion includes a successive pattern of protrusions separated by a distance that forms a gap between each of the protrusions, wherein each protrusion is configured to collapse into and fill the gap in response to the protective cover receiving an impact force on a corresponding location of the outer portion, and
a backplane coupled to a backside of the housing and is configured to provide a protective shell along a back side of the mobile display device.

US Pat. No. 10,165,837

RECONFIGURABLE STORAGE DEVICE

ACCO BRANDS CORPORATION, ...

1. A storage device comprising:a body having an inner compartment and a carrying handle, wherein said body has first and second outer portions and a middle portion positioned therebetween;
a strap attachable to said body in a first configuration wherein said strap is coupled to said body at or adjacent to said first and second outer portions and extends therebetween and is not coupled to said middle portion such that said strap is wearable over a shoulder of a user in a manner of a courier-type bag, and a second configuration wherein said strap is coupled to said body at or adjacent to said first and second outer portions and releasably slidably attached to handle to thereby define a pair of loops, each loop being shaped and configured to receive an arm of a user therethrough such that said storage device is wearable on a back of the user in the manner of a backpack; and
a securing device configured to releasably attach said strap to said handle, wherein said securing device includes a strap securing device that is slidably coupled to said strap such that the strap securing device can slide along a majority of the length of the strap and a handle securing device that is slidably coupled to said handle, wherein said strap securing device and said handle securing device are releasably attachable together, wherein strap securing device includes a closed, non-openable loop slidably receiving the strap therethrough and further includes a separate, selectively openable hook or clasp that does not slidably receive the strap therethrough.

US Pat. No. 10,165,832

METHOD OF MAKING A SOLE STRUCTURE COMPRISING A FLUID FILLED MEMBER WITH SLOTS

NIKE, Inc., Beaverton, O...

1. A method of making an article of footwear, comprising the steps of:receiving a fluid filled member including an internal cavity, the fluid filled member including at least one thickened portion; wherein the internal cavity has an X-like cross sectional shape, such that the internal cavity comprises a central cavity portion, a medial upper cavity portion extending from the central cavity portion and separate from a medial lower cavity portion extending from the central cavity portion, and a lateral upper cavity portion extending from the central cavity portion and separate from a lateral lower cavity portion extending from the central cavity portion;
forming a medial slot in the thickened portion in a medial side of the fluid filled member, the medial slot being disposed vertically between the medial upper cavity portion and the medial lower cavity portion;
forming a lateral slot in the thickened portion in a lateral side of the fluid filled member, the lateral slot being disposed vertically between the lateral upper cavity portion and the lateral lower cavity portion;
wherein the central cavity portion, the medial upper cavity portion, the medial lower cavity portion, the lateral upper cavity portion, and the lateral lower cavity portion are all disposed at a similar longitudinal position along a longitudinal direction;
wherein the central cavity portion, the medial upper cavity portion, the medial lower cavity portion, the lateral upper cavity portion, and the lateral lower cavity portion are all in fluid communication with one another at the similar longitudinal position; and
wherein a portion of each of the medial slot, the lateral slot, and a lower slot is disposed adjacent to the internal cavity.

US Pat. No. 10,165,830

SHOE UPPER

ASICS CORPORATION, (JP)

1. An upper of a shoe configured to cover at least a portion of a foot, the upper comprising:a medial side portion configured to cover a medial side surface of the foot;
a lateral side portion configured to cover a lateral side surface of the foot;
a plurality of panels provided in the medial side portion and/or the lateral side portion, configured to be separated from one another in a longitudinal direction of the foot, and configured to cover at least a portion of a side surface of the foot,
a fastening member configured to pull the panels toward a central portion between a medial side and a lateral side of the foot;
a plurality of string-shaped non-elongatable string portions extending in the longitudinal direction, the string portions placed between a pair of the plurality of panels that are adjacent to each other in the longitudinal direction;
a mesh member formed by a woven fabric or a knit fabric, having elongate slit-shaped through holes arranged in a plurality of columns and a plurality of rows; and
at least one panel member layered on the mesh member,
wherein each of the string portions is formed by a body part of the mesh member between two of the plurality of through holes that are configured to be spaced apart from, and adjacent to, each other in a circumferential direction of the foot.

US Pat. No. 10,165,829

SPACER TEXTILE MATERIAL WITH TENSILE STRANDS IN NON-LINEAR ARRANGEMENTS

NIKE, Inc., Beaverton, O...

1. A spacer textile material comprising:a first layer;
a second layer;
a plurality of connecting members extending between and joining the first layer and the second layer;
a tensile strand;
wherein the first layer is joined to the second layer to define a plurality of channels arranged in a non-linear pattern;
wherein the tensile strand extends through the plurality of channels;
wherein the plurality of channels includes a first channel that is oriented at a first angle relative to a first edge of the spacer textile material;
wherein the plurality of channels includes a second channel that is oriented at a second angle relative to the first edge of the spacer textile material;
wherein the plurality of channels includes a third channel that is oriented at a third angle relative to the first edge of the spacer textile material;
wherein the plurality of channels includes a fourth channel that is oriented at a fourth angle relative to a second edge of the spacer textile material, the second edge is opposite the first edge;
wherein the first angle and the second angle are different;
a first portion of the tensile strand extends from the second edge of the spacer textile material between the first channel and the second channel;
a second portion of the tensile strand extends from the first edge of the spacer textile material between the second channel and the third channel;
a third portion of the tensile strand extends from the second edge of the spacer textile material between the third channel and the fourth channel; and
a fourth portion of the tensile strand extends from a third edge of the spacer textile material.

US Pat. No. 10,165,827

OUTSOLE WITH GRIP REDUCTION EXTENSION MEMBERS

NIKE, Inc., Beaverton, O...

1. An outsole for an article of footwear, the outsole comprising:a sole foundation, the sole foundation having a first surface, the first surface configured as a ground-contacting surface;
a plurality of tread projections, each of the plurality of tread projections having a sidewall surface and a tread projection distal surface, the sidewall surface extending between the sole foundation first surface and the tread projection distal surface forming a distal surface offset distance, the tread projection distal surface having a first area; and
an extension member, the extension member comprised of a proximal portion and a distal portion, the extension member having an extension member length extending from the tread projection distal surface to an extension member distal end, the extension member having a cross sectional area perpendicular to the extension member length that is a second area, the first area being at least three times the area of the second area, the extension member length being at least twice a width of the second area, wherein the extension member length allows for flexibility that enables the extension member to be pushed sideways and to collapse and contact the tread projection distal surface, wherein the collapse of the extension member reduces traction of the article of footwear when worn.

US Pat. No. 10,165,826

ARTICLE OF FOOTWEAR WITH A MIDSOLE ASSEMBLY HAVING A PERIMETER BLADDER ELEMENT, A METHOD OF MANUFACTURING AND A MOLD ASSEMBLY FOR SAME

NIKE, Inc., Beaverton, O...

1. A method of manufacturing an article of footwear comprising:providing a first bladder element formed from first and second polymeric sheets to form the first bladder element with a substantially arc-shaped heel portion continuously extending to form a lateral arm portion extending forward from the heel portion along a lateral side of the first bladder element, and continuously extending to form a medial arm portion laterally-spaced from the lateral arm portion and extending forward from the heel portion along a medial side of the first bladder element;
providing a sole layer that has an upper surface and a lower surface, and that has multiple protrusions at the lower surface that extend away from the upper surface;
positioning the sole layer on the first bladder element so that the multiple protrusions of the sole layer extend away from the upper surface of the sole layer into a cavity between the lateral arm portion and the medial arm portion of the first bladder element; wherein the sole layer has at least one groove between at least two of the multiple protrusions; securing the sole layer to at least a portion of the first bladder element;
wherein the article of footwear is a first article of footwear; and simultaneously forming the first bladder element for the first article of footwear and a second bladder element for a second article of footwear in a single mold assembly;
wherein the second bladder element has a substantially arc-shaped heel portion continuously extending to form a lateral arm portion extending from the heel portion of the second bladder element along a lateral side of the second bladder element, and continuously extending to form a medial arm portion laterally-spaced from the lateral arm portion of the second bladder element and extending from the heel portion of the second bladder element along a medial side of the second bladder element;
wherein the medial arm portion of the first bladder element is between the lateral arm portion of the second bladder element and the medial arm portion of the second bladder element during said simultaneously forming;
wherein said simultaneously forming in the single mold assembly further includes forming a third bladder element and a fourth bladder element simultaneously with the first bladder element and the second bladder element in the single mold assembly;
wherein each of the third bladder element and the fourth bladder element has a substantially arc-shaped heel portion continuously extending to form a lateral arm portion extending from the heel portion, and continuously extending to form a medial arm portion laterally-spaced from the lateral arm portion and extending from the heel portion; and
wherein the medial arm portion of the third bladder element is between the lateral arm portion and the medial arm portion of the fourth bladder element during said simultaneously forming.

US Pat. No. 10,165,825

ARTICLE OF FOOTWEAR WITH ADAPTIVE FIT

NIKE, Inc., Beaverton, O...

1. A sole, comprising:an outer sole assembly including a plurality of outer sole members spaced apart from each other by a plurality of gaps;
a middle sole assembly defining a plurality of grooves; and
an intermediate layer comprising an elastomer, wherein the intermediate layer is disposed between the outer sole assembly and the middle sole assembly, and the intermediate layer connects the middle sole assembly to the outer sole assembly;
wherein the intermediate layer is more elastic than each of the plurality of outer sole members;
wherein the intermediate layer is more elastic than the middle sole assembly;
wherein one of the plurality of gaps is vertically aligned with a respective one of the plurality of grooves; and
wherein the plurality of gaps includes a forward central gap that extends from a forward edge of the outer sole assembly toward a heel region of the sole to separate the sole between a lateral portion and a medial portion.

US Pat. No. 10,165,824

SOLE MEMBER FOR AN ARTICLE OF FOOTWEAR

NIKE, Inc., Beaverton, O...

1. A sole structure for an article of footwear, the sole structure comprising:a first composite layer formed from first fibers having a first weave orientation and including a first raised portion extending from a first surface of the first composite layer in a first direction and a second raised portion extending from the first surface of the first composite layer in the first direction, the second raised portion being spaced apart from the first raised portion along a longitudinal axis of the sole structure and including a different shape than the first raised portion; and
a second composite layer attached to the first composite layer, formed from second fibers having a second weave orientation, and including a third raised portion extending from a first surface of the second composite layer in a second direction and a fourth raised portion extending from the first surface of the second composite layer in the second direction, the fourth raised portion being spaced apart from the third raised portion along a longitudinal axis of the sole structure and including a different shape than the third raised portion.

US Pat. No. 10,165,817

BATTERY PACK AND HELMET MOUNTING ARRANGEMENT

Revision Military S.a.r.l...

1. A helmet system comprising: a helmet; a battery pack having at least one battery;an attachment arrangement to removably attach the battery pack to the helmet, the attachment arrangement including a first engaging member on the battery pack, the first engaging member being coupleable to a second engaging member on the helmet;
a first electrical contact located on the battery pack, the first electrical contact configured to deliver power from the battery pack to a first device via an electrical contact on the helmet when the first device is attached to the helmet, wherein the first electrical contact delivers power from the battery pack to the first device only when the battery pack is attached to the helmet via the attachment arrangement, and wherein the first electrical contact cannot deliver power from the battery pack to the first device when the battery pack is completely removed from the helmet and the first engaging member on the battery pack is not coupled to the second engaging member on the helmet;
a mounting arrangement on the battery pack to removably mount a second device to the battery pack, the mounting arrangement including a third engaging member on the battery pack, the third engaging member being coupleable to a fourth engaging member on the second device, wherein the second device is physically supported by the battery pack when mounted to the battery pack via the mounting arrangement; and
a second electrical contact located on the battery pack and spaced from the first electrical contact, the second electrical contact configured to deliver power from the battery pack to the second device by an electrical contact on the second device when the second device is mounted to the battery pack, wherein the second electrical contact can deliver electrical power from the battery pack to the second device without the battery pack being electrically connected to the first device, wherein the first device and the second device are simultaneously operable when the battery pack is attached to the helmet via the attachment arrangement.

US Pat. No. 10,165,803

TEXTILE LINGERIE ARTICLE WITH IMPROVED HOLD

Hanes Operations Europe S...

1. A skin-contacting garment comprising:at least one holding element capable of holding the skin-contacting garment when it is worn, which holding element is constituted by a textile material provided on its inner surface intended to come in contact with the skin with a discontinuous coating of elastomeric material capable of preventing the slipping of this skin-contacting garment,
wherein the discontinuous coating of elastomeric material comprises a uniform pattern of protrusions of elastomeric material in the form of grains of rice having a distribution of omnidirectional orientation in a reference system of the inner surface of the holding element, where each respective protrusion comprises a longitudinal axis along a length of the respective protrusion and comprises a lateral axis along a width of the respective protrusion perpendicular to the length of the respective protrusion, the longitudinal axis defining a major axis of the respective protrusion, and the length of the protrusion being greater than the width of the protrusion,
wherein the distribution of relative orientation between adjacent protrusions is such that each protrusion has an orientation of its respective longitudinal axis that is different from and nonparallel to the longitudinal axis of each directly adjacent protrusion, which protrusions comprise dimensions and a distribution such that the density of the protrusions per surface unit of the holding element is at least 10 protrusions per square centimeter.

US Pat. No. 10,165,801

ELASTIC KNITTED MALE UNDERGARMENT

Hanes Operations Europe S...

1. A men's under-garment configured for a lower part of the body of a wearer, the under-garment comprising: a rear side and a front side including an upper belt part and a lower crotch part, the front side including a central part disposed vertically in a middle of the front side and intended to accommodate the genitals of the wearer, the central part including a relatively wide lower part for the crotch part, a relatively narrow upper part for the belt part, and side edges;elongated, elastic, reinforcing elements comprising elastic material and having an elongate structure attached substantially continuously to the front side and over the central part to reinforce support of the genitals;
wherein the elongated reinforcing elements are provided in a plurality of zones of the front side, the elongated elements forming at least one network of parallel lines in each zone of the plurality of zones, the plurality of zones comprising:
a) a support zone located at a bottom of the central part, the elongated elements having a roughly cradle-like shape in the support zone,
b) a control zone located at a top of the central part, the elongated elements having a roughly inverted-cradle-like shape in the control zone, wherein the elongated elements form two symmetrical networks which cross each other in the support zone and in the control zone, and
c) a reinforcement zone located on either lateral side of the central part, the elongated elements having a slanting direction in the reinforcement zone, wherein the elongated elements at the side edges of the central part are bound to the upper belt part of the front side to pull the support zone toward the top and the lateral sides of the undergarment, the elongated reinforcing elements in the reinforcement zone being heat-sealed to the front side of the under-garment.

US Pat. No. 10,165,795

METHOD FOR MANUFACTURING CURVED EDGE CIGARETTE ROLLING PAPER

Curved Papers, Inc., Pla...

1. A method of manufacturing packaged curved edge cigarette rolling papers comprising the steps of:stacking a multiplicity of rectangular cigarette rolling paper blanks to form a leaf stack having a top face, a bottom face opposing said top face, a front side, a back side opposing side front side, a spine side and a trim side opposing said spine side;
enclosing said leaf stack within a three sided folded cover which completely overlies the top face, spine side and bottom face to form a covered leaf stack having a trim end and an opposed spine end;
banding a portion of said covered leaf stack within a sleeve that wraps around the covered leaf stack overlying the top and bottom faces and contacting the front and back sides; and
cutting the cover and leaf stack at the trim end while said sleeve retains the leaf stack in alignment with said folded cover to form packaged curved edge cigarette rolling papers.

US Pat. No. 10,165,782

DEVICE FOR OPTICALLY IDENTIFYING THE SEX OF A SLAUGHTER PIG

CSB-System AG, Geilenkir...

1. A device for optically identifying the sex of a slaughtered slaughter pig, comprising:a depth camera having a depth camera capture region for capturing a genital region of the slaughter pig and spatial coordinates of pixels, the spatial coordinates being provided in transmittable form;
a tubular rail on which the slaughter pig is suspended accommodated with the hind legs thereof on the tubular rail with the hind legs arranged on the tubular rail and spaced apart longitudinally along movement axis of the tubular rail;
a positioning device supporting said depth camera and for positioning said depth camera in relation to the genital region of the slaughter pig, said positioning device arranging the depth camera orthogonally to said tubular rail; and
an analysis unit connected to said depth camera, said analysis unit capturing the spatial coordinates provided by said depth camera and ascertaining a phenotypic sex of the slaughter pig on the basis of the spatial coordinates, the phenotypic sex being a differentiation into male uncastrated, male castrated, male having entirely or partially internal testicles, and female.

US Pat. No. 10,165,750

LETTUCE VARIETY 41-200 RZ

RIJK ZWAAN ZAADTEELT EN Z...

1. A lettuce plant designated 41-200 RZ, representative seed of which having been deposited under NCIMB Accession No. 42342.

US Pat. No. 10,165,741

IRRIGATION SYSTEM WITH STEADY STATE SPEEDS OF MOVEMENT

Irrovation LLC, Omaha, N...

1. An irrigation system having a movement direction over a ground surface of a field, the irrigation system comprising:a plurality of spans, each having a longitudinal axis, said plurality of spans being connected at a flexible juncture and having a state of alignment of the respective longitudinal axes of the plurality of spans;
an intermediate tower structure between the plurality of spans configured to support the plurality of spans above the ground surface;
a variable-speed drive assembly of the intermediate tower structure having a wheel configured to contact the ground surface below the irrigation system and a span motor configured to drive the wheel so as to propel the intermediate tower structure over the ground surface;
an alignment detector of the variable-speed drive assembly having a first switch and a second switch configured to detect and output the state of alignment of the respective longitudinal axes of the plurality of spans indicating: (a) a lagging state of misalignment; (b) a leading state of misalignment; or (c) a state of alignment that is neither lagging nor leading;
the alignment detector having:
the first switch with a first arm, a first normally closed switch contact, a first normally opened switch contact, and a first common switch contact;
the second switch with a second arm, a second normally closed switch contact, a second normally opened switch contact, and a second common switch contact;
wherein the first and second arms detect and output the state of alignment of the respective longitudinal axes of the plurality of spans; and
a variable-speed drive controller of the variable-speed drive assembly controlling the speed of the intermediate tower structure over the ground surface, said variable-speed drive controller monitoring and processing the output of the alignment detector and, based on the state of alignment detected by the alignment detector, increasing the speed of the span motor in the lagging state of misalignment, decreasing the speed of the span motor in the leading state of misalignment, or maintaining the current speed of the span motor in the state of alignment that is neither lagging nor leading; to thereby maintain substantial straight alignment of the respective longitudinal axes of the plurality of spans.

US Pat. No. 10,165,734

GROWING SYSTEM MIXING BOX

Greenhouse HVAC, LLC, Ja...

1. A growing system mixing box comprising:a housing through which gaseous fluids flow;
a plurality of inlets to the housing, and an outlet from the housing, the outlet being spaced apart from the plurality of inlets, the plurality of inlets including a CO2-containing exhaust inlet;
a plurality of cooling coils, in series, disposed between the plurality of inlets and the outlet;
a heating coil, in series with the plurality of cooling coils, the heating coil being disposed between the plurality of cooling coils and the outlet.

US Pat. No. 10,165,730

METHOD OF OPERATING AN AGRICULTURAL BALER

CNH Industrial America LL...

1. A method of operating an agricultural baler, comprising the steps of:measuring with a sensor at least one physical input parameter associated with a compression profile of crop material in a bale chamber of the baler, wherein a plunger is configured for reciprocation within the bale chamber for compressing the crop material;
analyzing the compression profile of the crop material with a controller, dependent upon the measured at least one physical input parameter; and
adjusting at least one physical output parameter of the baler using a controller which affects the compression profile of the crop material in the bale chamber;
wherein analyzing the compression profile comprises:
performing a compression analysis and a relaxation analysis of the crop material within the bale chamber during bale formation.

US Pat. No. 10,165,726

AGRICULTURAL HEADER WITH MULTIPLE KNIFE DRIVES

CNH Industrial America LL...

1. An agricultural vehicle, comprising:a chassis; and
a header carried by said chassis, said header including:
at least three header frame sections, said at least three header frame sections comprising a center section, a first wing section adjacent a first lateral end of said center section, and a second wing section adjacent a second lateral end of said center section which is opposite said first lateral end;
at least three knife assemblies; and
at least three knife drives, each of said at least three knife drives being drivingly coupled to at least one of said at least three knife assemblies;
wherein said center section carries at least one of the at least three knife assemblies, and carries at least one of said at least three knife drives at a point between the first and the second lateral ends;
wherein said first wing section carries at least one of the at least three knife assemblies, and carries one of said at least three knife drives adjacent an end opposite said first lateral end of said center section; and
wherein said second wing section carries at least one of the at least three knife assemblies, and carries one of said at least three knife drives adjacent an end opposite said second lateral end of said center section.

US Pat. No. 10,165,723

SEED TREATMENT APPARATUS

Bayer CropScience LP, Re...

1. A method of treating seeds with a seed treatment apparatus having a control processor, the method comprising:(a) depositing a plurality of seeds through a seed inlet in the seed treatment apparatus into a seed meter, wherein the seed meter comprises a rotatable seed wheel having an outer surface and a plurality of slots, thereby depositing into each slot a preset metered volume of the plurality of seeds;
(b) controlling the seed meter by the control processor to provide a volumetric flow rate of seeds passing therethrough;
(c) sensing the seed in the inlet above the seed meter and sending data to the control processor for determining when the seed meter will run out of seed for metering;
(d) discharging the seeds from the seed meter at the volumetric flow rate through a seed treatment region of a seed treatment applicator;
(e) individually pumping from at least one of a plurality of treatment tank units treatment fluid into the seed treatment applicator, each one of said plurality of treatment tank units comprising a pump and controlling each one of said pumps by the control processor thereby regulating a volumetric flow rate and thereby coating the seeds passing through the seed treatment region at least one of a plurality of a predetermined range of ratios of the volumetric flow rate of treatment fluid to the volumetric flow rate of the seed, with the treatment fluid from the plurality of treatment tank units; and
(f) discharging a plurality of treated seeds from the seed treatment applicator;
wherein when one of the flow rate of the treatment fluid pumped to the seed treatment applicator and the volumetric flow rate of seeds changes during the seed treatment, the other is automatically changed by the control processor thereby maintaining a predetermined ratio of the volumetric flow rate of treatment fluid to the seed volumetric flow rate,wherein after the seeds are treated by the rotatable seed wheel, the seeds are discharged into a tumbling drum for additional coating of the seeds by seed to seed contact and wherein the rotatable seed wheel is positioned between the treatment application portion and a seed discharge portion.
US Pat. No. 10,167,380

COMPOSITE MATERIAL

FiberSpec LLC, Two River...

1. A composite material, comprising:a plurality of beads, each bead having a diameter of at least 0.05 mm;
a plurality of fibers, each fiber having a length and a width; and
a resin binder;
wherein, the length of each fiber is greater than the width of each fiber; and
wherein the width of each fiber is less than the diameter of each bead.
US Pat. No. 10,170,212

METAL-CONTAINING COMPOUNDS

FARADION LIMITED, Sheffi...

1. A solid state process for preparing a metal-containing compound comprising the formula:AaMb(XcYd)eZf
wherein:
A is an alkali metal selected from one or more of sodium and potassium;
M comprises one or more metals selected from the group consisting of titanium, vanadium, niobium, tantalum, hafnium, chromium, molybdenum, tungsten, manganese, iron, osmium, cobalt, nickel, palladium, platinum, copper, silver, gold, zinc, cadmium, aluminium, scandium, yttrium, zirconium, technetium, rhenium, ruthenium, rhodium, iridium, mercury, gallium, indium, tin, lead, bismuth, magnesium, calcium, beryllium, strontium barium, boron, silicon, germanium, arsenic, antimony and tellurium;
(XcYd) is at least one first anion and is a moiety selected from one or more of PO4 and/or P2O7; and
Z is at least one second anion
wherein a>0; b>0; c>0; d>0; e>0 and f?0;
wherein a, b, c, d, e and f are chosen to maintain electroneutrality;
comprising the steps:
a) forming a mixture of starting materials in their solid form, comprising i) one or more M metal-containing precursor compounds, ii) one or more A metal-containing and hypophosphite-containing materials;
b) heating the mixture of starting materials from 150° C. to 1200° C. in the absence of an oxidizing atmosphere to form the metal-containing compound; and
c) recovering the metal-containing compound.
US Pat. No. 10,170,213

SILVER POWDER AND METHOD FOR PRODUCING SAME

Dowa Electronics Material...

4. A silver powder, the surface of which is coated with a fatty acid, wherein an aliphatic amine is formed on the outermost of the silver powder, and wherein an aliphatic amide is formed between the fatty acid and the aliphatic amine.
US Pat. No. 10,166,120

ORTHOPEDIC DEVICE AND POLYMER COMPOSITIONS FOR MAKING SAME

Ticona LLC, Florence, KY...

1. A polymer composition comprising:a polyoxymethylene polymer, the polyoxymethylene polymer having a melt volume flow rate of less than 15 cm3/10 min when tested at 190° C. under a load of 2.16 kg, the polyoxymethylene polymer being present in the polymer composition in an amount of at least 70% by weight; and
a copolyamide and a dicyandiamide blended with the polyoxymethylene polymer, the copolyamide and the dicyandiamide being present in the composition at a weight ratio of greater than 2:1.
US Pat. No. 10,167,416

HIGH PERFORMANCE WATER-BASED ADHESION COMPOSITIONS AND APPLICATIONS

HONEYWELL INTERNATIONAL I...

1. An adhesion composition comprising:(a) a first polymer, having a number average molecular weight greater than about 50,000 Daltons but not greater than about 100,000 Daltons, and chosen from acrylic polymers comprising a majority component of either 2-ethylhexylacrylate or butyl acrylate copolymerized with a minority component of either methyl methacrylate, vinyl acetate, or styrene;
(b) a second polymer different than said first polymer, having a number average molecular weight less than about 20,000 Daltons, and consisting of ethylene-acrylic acid copolymers in combination with an oxidized polyethylene polymer;
(c) surfactant in an amount of about 0.05% to about 0.5%; and
(d) water, where the amount of said water, said first polymer and said second polymer is sufficient to provide the composition with a solids content of greater than about 30% based on the total weight of components (a)-(d) in the adhesion composition and where said first polymer and said second polymer comprise solid particles having a D50 particle size of from about 10 nanometers (nm) to about 2000 nm.
US Pat. No. 10,170,749

ALKALI METAL BATTERY HAVING AN INTEGRAL 3D GRAPHENE-CARBON-METAL HYBRID FOAM-BASED ELECTRODE

Nanotek Instruments, Inc....

1. An alkali metal battery having an anode, a cathode, an electrolyte in ionic contact with said anode and said cathode, and an optional porous separator electronically separating said anode and said cathode, wherein said anode comprises an integral 3D graphene-carbon-metal hybrid foam comprised of multiple pores, pore walls, and a lithium-attracting metal or sodium-attracting metal residing in said pores or deposited on said pore walls; wherein said lithium-attracting metal is selected from the group consisting of Au, Ag, Mg, Zn, Ti, Na, K, Al, Fe, Mn, Co, Ni, Sn, V, Cr, and an alloy thereof for a lithium metal battery, or said sodium-attracting metal is selected from the group consisting of Au, Ag, Mg, Zn, Ti, Li, K, Al, Fe, Mn, Co, Ni, Sn, V, Cr, and an alloy thereof for a sodium metal battery, and is in an amount of 0.1% to 90% of the total hybrid foam weight, and said pore walls comprise single-layer or few-layer graphene sheets chemically bonded by a carbon material having a carbon material-to-graphene weight ratio from 1/200 to 1/2, wherein said few-layer graphene sheets have 2-10 layers of stacked graphene planes having an inter-plane spacing d002 from 0.3354 nm to 0.40 nm as measured by X-ray diffraction and said single-layer or few-layer graphene sheets comprise a pristine graphene material having essentially zero % of non-carbon elements, or a non-pristine graphene material having 0.001% to 25% by weight of non-carbon elements wherein said non-pristine graphene is selected from graphene oxide, reduced graphene oxide, graphene fluoride, graphene chloride, graphene bromide, graphene iodide, hydrogenated graphene, nitrogenated graphene, doped graphene, chemically functionalized graphene, or a combination thereof; wherein said integral 3D graphene-carbon-metal hybrid foam is pre-loaded with lithium or sodium before said battery is made, or said anode further comprises a lithium source or a sodium source.
US Pat. No. 10,170,750

LITHIUM-CONDUCTING SULFUR COMPOUND CATHODE FOR LITHIUM-SULFUR BATTERIES

UT-BATTELLE, LLC, Oak Ri...

1. A method of making a cathode for a battery, comprising the steps of:reacting sulfur with Li3PS4 in a liquid solvent to provide a composition comprising Li3PS4+n (0 creating a slurry with the compound, a binder and carbon; and
coating a current collector with the slurry and forming a cathode with the slurry.
US Pat. No. 10,166,395

INHIBITION OF INFLAMMATORY CYTOKINE PRODUCTION BY CHOLINERGIC AGONISTS AND VAGUS NERVE STIMULATION

The Feinstein Institute f...

1. A method for treating inflammation by inhibiting an inflammatory cytokine cascade in a patient, wherein the method comprises:evoking a sustained inhibition of the patient's inflammatory cytokine cascade by electrically stimulating the patient's vagus nerve for a first duration, followed by a second duration during which the patient's vagus nerve is not electrically stimulated, wherein the second duration is at least three times longer than the first duration,
wherein at the end of the second duration the levels of inflammatory cytokines are inhibited by at least 20% over the untreated state, and wherein the patient's heart rate remains stable for 10 minutes after the vagus nerve is electrically stimulated.
US Pat. No. 10,170,754

SILICON MONOXIDE COMPOSITE NEGATIVE ELECTRODE MATERIAL USED FOR LITHIUM ION BATTERY, THE PREPARATION METHOD THEREOF AND A LITHIUM ION BATTERY

Shenzhen BTR New Energy M...

1. A silicon monoxide composite negative electrode material, which comprises, from inside to outside, a silicon monoxide substrate, a carbon material coating layer on the surface of the substrate, a crystalline nano-silicon material uniformly deposited on the carbon material coating layer and a nanoscale conductive material coating layer on the surface of the silicon monoxide substrate/carbon material coating layer/crystalline nano-silicon material, wherein the crystalline nano-silicon material is mono-dispersed nano-silicon particles with an average particle size of 1.0-1000.0 nm.
US Pat. No. 10,167,425

ETCHING SOLUTION CAPABLE OF SUPPRESSING PARTICLE APPEARANCE

OCI COMPANY LTD., Seoul ...

1. An etching solution for suppressing particle appearance comprising:an aqueous solution including phosphoric acid;
a first silane compound including 1 to 6 silicon atoms where at least one silicon atom is bonded to three or more hydrophilic functional groups, wherein a concentration of the first silane compound in the etching solution ranges from 100 ppm to 10,000 ppm;
a second silane compound including 1 to 6 silicon atoms where the number of hydrophilic functional groups bonded to one silicon atom is a maximum of 2, wherein a concentration of the second silane compound in the etching solution ranges from 100 ppm to 30,000 ppm; and
a fluorine-containing compound.
US Pat. No. 10,167,435

LIQUID COMPOSITIONS FOR MARKING LIQUID HYDROCARBON MOTOR FUELS AND OTHER FUELS, MOTOR FUELS AND OTHER FUELS CONTAINING THEM AND PROCESS FOR DETECTING THE MARKERS

Total Marketing Services,...

1. A process for the qualitative detection of at least one marker in a motor fuel or other liquid hydrocarbon fuel comprising:(a) the at least one marker, chosen from the following aliphatic or cycloaliphatic compounds:
tricyclodecenyl isobutyrate (3a,4,5,6,7,7a-hexahydro-4,7-methano-1 h-inden-5 (or 6) -yl) (CAS 67634-20-2);
tricyclodecenyl propionate (CAS 17511-60-3);
cis-3- hexenyl acetate (CAS 3681-71-8);
ethyl linalool (CAS 10339-55-6);
prenyl acetate (CAS 1191-16-8);
ethyl myristate (CAS 124-06-1);
para-tert-butylcyclohexyl acetate (CAS 32210-23-4);
tricyclodecenyl acetate (4,7-methano-1h-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-) (CAS 5413-60-5);
ethyl caprate(CAS 110-38-3),
the at least one marker having a concentration of from 1 ppm to 20 ppm with regard to the motor fuel or other liquid hydrocarbon fuel;
(b) a solvent or a mixture of solvents; and
(c) one or more functional additives for motor fuels and/or other liquid hydrocarbon fuels, chosen from the detergents, dispersants, combustion improvers, anti-foaming agents, conductivity improvers, anti-corrosion additives, lubricity additives, anti-wear agents and/or friction modifiers, chelating agents and/or sequestrating agents of metals, demulsifiers, low temperature behaviour additives, metal passivators, acidity neutralizers, markers different from the markers; the process comprising the following steps:
analyzing a sample of the motor fuel or other liquid fuel containing the at least one marker by an analytic method; and
then detecting the at least one marker.
US Pat. No. 10,166,412

SKIN LIGHTENING COMPOSITION COMPRISING 4-HEXYLRESORCINOL AND ILOMASTAT

Conopco, Inc., Englewood...

1. A skin lightening composition comprisinga) an effective amount of 4-hexylresorcinol; and
b) an effective amount of galardin.
US Pat. No. 10,167,447

SUPPORTS AND METHODS FOR PROMOTING INTEGRATION OF CARTILAGE TISSUE EXPLANTS

Zimmer, Inc., Warsaw, IN...

1. A method of making a cartilage tissue construct, the method comprising:placing a first surface of a first cartilage tissue piece and a first surface of a second cartilage tissue piece adjacent to an exposed surface of a solid or semi-solid support, wherein at least one of the first cartilage tissue piece and the second cartilage tissue piece comprises a cartilage explant;
culturing, in vitro, the first cartilage tissue piece and the second cartilage tissue piece on the exposed surface of the support, including reorienting at least one of the first cartilage tissue piece and the second cartilage tissue piece, relative to the support, to direct the expansion or shape of the reoriented cartilage tissue piece.
US Pat. No. 10,167,448

PHARMACEUTICAL COMPOSITION FOR TREATING CEREBROVASCULAR DISEASES, CONTAINING STEM CELL-DERIVED EXOSOME AS ACTIVE INGREDIENT

Samsung Life Public Welfa...

1. A method for treating a cerebrovascular disease, comprising:administering to a subject having the cerebrovascular disease an effective amount of exosome derived from a stem cell,
wherein the cerebrovascular disease is intraventricular hemorrhage (IVH), and
wherein the stem cell is a mesenchymal stem cell.
US Pat. No. 10,167,454

COMPOSITIONS USEFUL IN TREATMENT OF ORNITHINE TRANSCARBAMYLASE (OTC) DEFICIENCY

The Trustees of the Unive...

1. A recombinant viral vector comprising a nucleic acid sequence encoding human ornithine transcarbamylase (hOTC) and expression control sequences which direct expression of hOTC in a liver cell, wherein the hOTC nucleic acid sequence is less than 80% identical to the wild-type hOTC sequence over the mature sequence or full length hOTC of SEQ ID NO: 1, and expresses a functional hOTC, wherein said hOTC nucleic acid sequence is SEQ ID NO: 5 or a nucleic acid sequence at least 96 to 99% identical thereto.
US Pat. No. 10,167,455

RECOMBINANT POLYMERASES FOR IMPROVED SINGLE MOLECULE SEQUENCING

Pacific Biosciences of Ca...

1. A composition comprising a recombinant DNA polymerase, which recombinant polymerase comprises an amino acid sequence that is at least 80% identical to SEQ ID NO: 1 or SEQ ID NO: 2, which recombinant polymerase comprises an amino acid substitution at position E420, wherein identification of positions is relative to SEQ ID NO: 1, and which recombinant polymerase exhibits polymerase activity.
US Pat. No. 10,167,456

BIFUNCTIONAL LIPASE MUTANT AND METHODS OF USING SAME

JIANGNAN UNIVERSITY, Wux...

1. A method of processing flour products with a lipase mutant,wherein the lipase mutant comprises:
an amino acid sequence with substitutions selected from the group consisting of P298T, P298T/H317P, P298T/H317P/V326S, P298T/T218S/S234F, P298T/H317P/P168L/A129S, and P298T/S234F/K161R/V326S, wherein the substitutions are relative to a parent amino acid sequence set forth in SEQ ID NO: 1;
wherein the lipase mutant maintains a triglyceride and lecithin hydrolysis activity and thermostability; and
wherein the method comprises:
expressing the lipase mutant from a culture of a recombinant yeast strain comprising an expression vector for the lipase mutant;
preparing a purified form of the lipase mutant from the culture; and
adding the purified form of the lipase mutant to a flour and water mix to obtain flour products.
US Pat. No. 10,167,203

PREPARATION OF SUSPENSIONS

THE UNIVERSITY OF QUEENSL...

1. A method for preparing a suspension of LDH particles comprising the steps of:a) preparing LDH precipitates by coprecipitation to form a mixture of LDH precipitates and solution, wherein the LDH precipitates and the solution formed in step (a) are left in contact with each other for a period not exceeding 30 minutes;
b) separating the LDH precipitates from the solution;
c) washing the LDH precipitates to remove residual ions;
d) mixing the LDH precipitates with water; and
e) subjecting the mixture of LDH particles and water from step (d) to a hydrothermal treatment step by heating to a temperature of from greater than 80° C. to 150° C. for a period of about 1 hour to about 144 hours to form a dispersed suspension of non-aggregated LDH particles in water, wherein said LDH particles in suspension comprise platelets having a maximum particle dimension of up to 400 nm.
US Pat. No. 10,166,693

TREATED POROUS MATERIAL

Dow Global Technologies L...

1. A method for preparing a treated cellulosic material comprising:(a) providing a cellulosic material comprising wood or wood composite materials;
(b) a first treatment protocol comprising impregnating the cellulosic material under a pressure greater than or lower than ambient with an aqueous dispersion comprising a polymer, the polymer comprising an olefin-carboxylic acid copolymer; and
(c) a second treatment protocol comprising impregnating the cellulosic material under a pressure greater than or lower than ambient with a modifying agent, the modifying agent comprising a bivalent, trivalent, or tetravalent metal ion.
US Pat. No. 10,166,182

INACTIVATED WHOLE VIRION VACCINE-CONTAINING MICRONEEDLE ARRAY PREPARATION AND METHOD FOR ADMINISTERING THE SAME

FUJIFILM Corporation, To...

1. A microneedle array comprising:a needle portion containing an inactivated whole virion influenza vaccine; and
a sheet portion,
wherein 90% by mass or more of the inactivated whole virion influenza vaccine with respect to the total mass of the vaccine is contained in a region that accounts for not more than 60% of the height of the needle portion from a tip of the needle portion; and
the height of the needle portion is equal to or greater than 50 ?m and equal to or less than 2,000 ?m, and
wherein the needle portion contains a water-soluble polymer, and the water-soluble polymer contains at least hydroxyethyl starch.