US Pat. No. 10,113,685

DISPLAY DEVICE

LG Display Co., Ltd., Se...

1. A display device, comprising:a display panel;
a back cover onto which the display panel is seated; and
a bending member, the bending member comprising:
a fixing member coupled to a back surface of the back cover to change curvatures of the display panel and the back cover;
a pair of holder members coupled to the back cover and spaced apart from the left and right sides of the fixing member;
a pair of support members respectively hinge-coupled to the pair of holder members such that one end of each of the pair of support members respectively supports left and right sides of the back cover; and
a sliding member slidably coupled to the fixing member to rotate the support members,
wherein the sliding member comprises a front inclined surface, the front inclined surface supporting the support members while sliding vertically,
wherein the front inclined surface of the sliding member is located on a top surface of the support member at a maximum vertical sliding position, and
wherein the front inclined surface of the sliding member is located directly between the support members and the fixing member at a vertical sliding position below the maximum vertical sliding position.

US Pat. No. 10,113,668

SUBSEA FORTIFIED ZONE MODULE

5. A method for conveying fluids at an underwater subsea location, comprising:positioning a module at the underwater subsea location, the module having a flow line for flowing fluids in a serial fashion from a single inlet to a single outlet, the flow line being shaped to reverse flow of the fluids a plurality of times along each plane of a plurality of planes, and wherein the flow line conforms to a flow pattern that reverses flow along non-parallel planes; and
flowing fluids from a high-integrity pressure protection system (HIPPS) to a subsea production system via the module.

US Pat. No. 10,113,666

MARINE PIPELAYING SYSTEM AND METHOD FOR LOWERING AND/OR RAISING AN OFFSHORE PIPELINE AND INCLUDING ONE OR MORE ACCESSORIES THERETO

ITREC B.V., Schiedam (NL...

1. A marine pipelaying system to be mounted on a vessel for lowering and/or raising an offshore pipeline and including one or more accessories thereto, the system comprising:a pipeline launch device for lowering/raising the offshore pipeline along a firing line defined by the pipeline launch device;
a pipeline clamp adapted to clamp and support the weight of a lowered portion of the offshore pipeline in the firing line;
an accessory handling device comprising an accessory transport track supported by the pipeline launch device above the pipeline clamp, extending horizontally and providing an engagement position and a pipeline connecting position, the accessory handling device further comprising a cart, movable along the accessory transport track via an associated cart drive, the cart being adapted to engage and support one of the one or more accessories, such that the accessory handling device is adapted to:
engage said accessory at the engagement position;
position said accessory in the pipeline connecting position in the firing line above the pipeline clamp, wherein the accessory can be connected to the pipeline; and
support and allow displacement of the accessory between the engagement position and the pipeline connection position;
an accessory connecting device, adapted to connect the one or more accessories to the offshore pipeline; and
a controlled load hoisting device adapted to be releasably secured to one of the one or more accessories and lower/raise said accessory and a lowered portion of the offshore pipeline connected thereto,
wherein the accessory handling device further comprises:
an elongated hoist beam, supported by the cart, extending horizontally and perpendicular to the accessory transport track, comprising trolley rails in the longitudinal direction of the hoist beam;
a travelling trolley displaceable along the trolley rails, and an associated trolley drive to displace the travelling trolley along the trolley rails;
an object suspension device, adapted to engage and support at least one of the one or more accessories; and
a hoist assembly comprising a hoist winch and an associated hoisting cable, the hoisting cable extending from the hoist winch via the travelling trolley to the object suspension device, such that upon actuation of the hoist winch the object suspension device can be raised and lowered.

US Pat. No. 10,113,663

WATER METER LOCKING DEVICE

1. A valve lock assembly useful in securing access to the valves of a valve system, the valve lock assembly comprisinga) a housing defined by a top and a skirt, the skirt extending down from the top forming a vacuous area within the housing, the housing having a dual-sided corner brace affixed to the housing top, wherein the corner brace is defined by a pair of adjacent side walls and a top, to form a space with limited accessibility, and wherein the housing top and the brace top have aligned apertures; and
b) a removable lock assembly, wherein the removable lock assembly comprises a coil rod positioned to be received in the aligned apertures of the housing top and the brace top, and further rotationally supports a plurality of dowel pins.

US Pat. No. 10,113,662

LIQUID DISPENSING FAUCET WITH PULL-TO-OPEN VALVE ELEMENT

The Meyer Company, Cleve...

1. A faucet for dispensing liquid, said faucet comprising:a body including an inner end adapted to be connected to an associated liquid container and including an outer end comprising a liquid spout for dispensing liquid, said body including a flow passage that extends from an inlet located in said inner end of said body to an outlet located in said spout;
said body comprising a valve chamber therein and defined by part of said flow passage, said valve chamber located between said inlet and said outlet such that said valve chamber separates said flow passage into an inlet portion located between said inlet and said valve chamber and an outlet portion located between said valve chamber and said outlet;
said body further comprising a valve seat located in said valve chamber and a valve chamber access opening that communicates with the valve chamber;
a bonnet connected to the body and covering the access opening, said bonnet comprising a bonnet aperture therein;
a valve assembly that controls flow of liquid through the valve chamber, said valve assembly comprising: (i) a valve element selectively movable between a seated position in which the valve element is engaged with the valve seat to block liquid flow past the valve seat, and an unseated position in which the valve element is disengaged from the valve seat to allow liquid flow past the valve seat; (ii) a valve stem that extends through the bonnet aperture and that comprises an inner end operably connected to the valve element and an outer end located external to the body;
a handle operably connected to the outer end of the valve stem, said handle movable linearly in a first direction from a retracted position to an extended position;
a spring operably engaged with the valve element and biasing the valve element toward its seated position;
a reaction structure located adjacent the handle and adapted to be engaged by a user during movement of the handle from its retracted position toward its extended position, wherein said reaction structure comprises an exposed end of a shaft that projects outwardly from said bonnet;
wherein said valve element is selectively moved from its seated position to its unseated position by manual linear movement of the handle in a first direction from its retracted position toward its extended position, said movement of said handle in said first direction inducing movement of the valve stem and valve element in the first direction; and
wherein said handle comprises a handle bore and said shaft extends through said handle bore such that said exposed end of said shaft defines a button that extends outwardly from the handle bore.

US Pat. No. 10,113,647

SEALING STRIP FOR A SEALING DEVICE IN A MACHINE FOR PROCESSING A PAPER, CARDBOARD, OR TISSUE WEB

Voith Patent GmbH, Heide...

1. A sealing strip for a sealing device for sealing a pressure or vacuum zone of a suction roll, the sealing strip comprising:an upper side with a sealing face and a lubricant channel adjoining said sealing face, said lubricant channel being at least one groove-type depression formed in said sealing strip and extending in a longitudinal direction of said sealing strip;
wherein, on installation of said sealing strip in the roll, said sealing face and an opening of said groove-type depression face toward an inner side of a roller sleeve;
at least one supply line hooked up to said lubricant channel, said at least one supply line, at least in portions thereof, running within said sealing strip and delivering lubricant to between the inner side of the roller sleeve and said sealing face; and
said sealing strip having a length delimited by two ends and a respective wall integrally formed at each of said two ends delimiting a length of said lubricant channel.

US Pat. No. 10,113,637

INTEGRATED POWERTRAIN SYSTEM

Cummins, Inc., Columbus,...

1. A method, comprising:receiving a predetermined shift schedule for a transmission of a vehicle from a remote source;
interpreting vehicle operation data regarding operation of the vehicle;
interpreting a desired operating characteristic of a vehicle operating parameter;
determining a predicted impact of a scheduled shift event of the predetermined shift schedule on the vehicle operating parameter based on the vehicle operation data; and
selectively adjusting the scheduled shift event in response to the desired operating characteristic and the predicted impact on the vehicle operating parameter,
wherein selectively adjusting the scheduled shift event includes at least one of a delay of the scheduled shift event, an early implementation of the scheduled shift event, and a skipping of the scheduled shift event, and implementing the adjusted shift event with the transmission.

US Pat. No. 10,113,624

TORSIONAL VIBRATION DAMPER AND LOCK-UP CLUTCH FOR HYDROKINETIC TORQUE-COUPLING DEVICE, AND METHOD FOR MAKING THE SAME

Valeo Embrayages, Amiens...

1. A hydrokinetic torque-coupling device for coupling a driving shaft and a driven shaft together, comprising:a casing rotatable about a rotational axis and having a locking surface;
a torque converter including an impeller wheel rotatable about the rotational axis and a turbine wheel disposed in the casing coaxially with the rotational axis, the turbine wheel disposed axially opposite to the impeller wheel and hydro-dynamically rotationally drivable by the impeller wheel;
a lock-up clutch including a locking piston axially moveable along the rotational axis to and from the locking surface of the casing, the locking piston having an engagement surface configured to selectively frictionally engage the locking surface of the casing to position the hydrokinetic torque-coupling device into and out of a lockup mode in which the locking piston is mechanically frictionally locked to the casing so as to be non-rotatable relative to the casing; and
a torsional vibration damper comprising
a torque input member including a radially oriented first retainer plate and at least one supporting member mounted thereto; and
a unitary radially elastic output member pivotable relative to and elastically coupled to the torque input member;
the radially elastic output member including an annular output hub coaxial with the rotational axis and rotatable relative the torque input member, and at least one curved elastic leaf integral with the output hub and configured to elastically and radially engage the at least one supporting member and to elastically bend in the radial direction upon rotation of the first retainer plate with respect to the radially elastic output member;
the at least one curved elastic leaf having a proximal end non-moveably connected to the output hub, a free distal end and a curved raceway portion disposed between the proximal and free distal ends of the at least one elastic leaf for bearing the at least one supporting member;
the annular output hub of the radially elastic output member being configured for directly and non-rotatably engaging the driven shaft; and
the locking piston of the lock-up clutch non-rotatably connected to the torque input member of the torsional vibration damper.

US Pat. No. 10,113,622

INTEGRALLY DRIVEN LINKAGE FOR INDUSTRIAL/COMMERCIAL EQUIPMENT

Nor-Tech Industrial Corp....

1. An integrally driven linkage having a longitudinal axis comprising:a plurality of link members,
a plurality of substantially cylindrical axles interconnecting the link members, the link members being arranged along the longitudinal axis of a carrier into inner link members that are flanked on each side by outer link members, the outer link members extend between adjacent link members, a pair of apertures defined in each of the link members, the inner and outer link members being arranged such that they partly overlap with respective apertures in alignment, the inner and outer link members being interconnected by the transverse axles that are received in the aligned apertures, the inner link members each include a pair of opposed link plates that are received in the apertures of the inner link plates and serve to join together the opposed inner links, the axles being arranged so as to receive bearings upon which double sheaves may freely rotate, the axles being rotatable on the link members so as to allow the inner link members to articulate relative to the outer link members, the outer link members being configured so articulation is limited to one direction only.

US Pat. No. 10,113,620

BALL RETURNING CIRCULATOR OF BALL SCREW

PMI PRECISION MOTION INDU...

1. A ball returning circulator of a ball screw having a nut, a screw and a plurality of balls, the ball returning circulator comprising:at least one ball access port, each of the at least one ball access port at one end of the circulator for releasing balls to come into or out from the circulator; and
at least one curved section having at least one opening distanced from the ball access port and at least one cover plate for closing the at least one opening;
wherein the ball returning circulator comprises two circulation tubes, each of the circulation tubes has one said ball access port, a connecting section, one said curved section and a ball engaging section, each said curved section having the opening is between the connecting section and the ball engaging section, and the connecting section of the circulation tube has at least one positioning wing frame on at least one side thereof.

US Pat. No. 10,113,613

PLANETARY GEAR MECHANISM AND POWER TRANSMISSION MEMBER THEREOF

Hiedkazu Atari, Tokyo (J...

1. A power transmission member provided as a power transmission member of a planetary gear mechanism configured to support, in a freely turnable manner, a planetary gear to be engaged with a sun gear and an internal gear, comprising:a planetary gear holding portion in which a planetary gear attachment portion to attach the planetary gear in a freely turnable manner is formed in a rotary shaft direction, a bearing portion to support, in a freely turnable manner, one end of the planetary gear attached to the planetary gear attachment portion is formed in a rotary shaft direction and communicates with the one end of the planetary gear attachment portion, and an open window is formed on a peripheral surface such that a tooth portion of the planetary gear attached to the planetary gear attachment portion projects from an outer peripheral surface;
a substantially cylindrical-shaped rotary shaft portion configured to communicate with the other end of the planetary gear holding portion, and having a rotation support hole that is formed in the rotary shaft direction and supports, in a freely turnable manner, the other end of the planetary gear attached to the planetary gear attachment portion; and
a sun gear holding portion having a sun gear insertion hole that is formed in a rotary shaft direction and is adapted to insert a shaft portion of the sun gear into a center shaft of the planetary gear holding portion in a freely turnable manner,
wherein the planetary gear holding portion, the rotary shaft portion, and the sun gear holding portion are formed as an integrated body, and
the planetary gear is inserted from an opening end portion of the rotary shaft portion, and is attached to the planetary gear attachment portion via the rotation support hole.

US Pat. No. 10,113,589

AXIALLY SELF-POSITIONING RADIAL SUPPORT BEARING

KOYO BEARINGS NORTH AMERI...

1. A radial support bearing assembly for use with a shaft defining an annular groove in its outer surface, comprising:a substantially cylindrical cage including a central portion extending between a first end portion and a second end portion, the central portion defining a plurality of roller pockets, a first projection and a second projection extending radially outwardly from the outer surface of the cage, and at least one projection extending radially inwardly from an inner surface of the cage;
a plurality of rollers, each roller being disposed in a respective roller pocket; and
a substantially cylindrical outer sleeve having an inner surface and an outer surface, the outer sleeve being disposed about an outer surface of the cage so that the inner surface of the outer sleeve is adjacent the plurality of rollers, and the outer sleeve being axially retained between the first projection and the second projection,
wherein the at least one projection is operatively engaged with the annular groove in the shaft so that the cage is axially fixed with respect to the shaft.

US Pat. No. 10,113,585

CABLED BEARING

AKTIEBOLAGET SKF, Gothen...

1. A rolling element bearing comprising,a first bearing ring,
a second bearing ring,
at least one row of rolling elements disposed between raceway surfaces of the bearing rings,
a sensing element provided on a sensing surface of the first bearing ring, and a signal cable connected to the sensing element, wherein
the signal cable includes a cable connector that fits into a socket, and wherein the socket is at least partly integrated in a recess provided in an external surface of the first bearing ring, wherein
the recess is in communication with the sensing surface, and wherein
a signal coupling is arranged between the sensing element and the socket; and
one of the cable connector and the socket has an angled body section that is angled with a first angle ? relative to a longitudinal axis of the recess, such that the cable is guided out of the recess at an angle to a normal of the external surface in a substantially circumferential direction of the bearing.

US Pat. No. 10,113,573

SEQUENCING LOCKING MECHANISM FOR TELESCOGING STRUCTURES

Raytheon Company, Waltha...

1. A passive locking mechanism for a telescoping structure, comprising:a stud fixed to a first panel section;
a lower pawl coupled to a second panel section;
an upper pawl coupled to the second panel section, the upper pawl operable to engage the lower pawl; and
a lock wedge coupled to a third panel section, the lock wedge being operable to engage the upper and lower pawls,
wherein, in a retracted position of the telescoping structure, the lower pawl is engaged with the lock wedge, such that the second panel section is locked in place relative to the third panel section, and
wherein the first panel section is free to move relative to the second panel section.

US Pat. No. 10,113,570

SYSTEM AND METHOD FOR IN-SITU STATE MONITORING OF A HYDRAULIC SYSTEM

Mera AS, Haugesund (NO)

1. A monitoring system for in-situ monitoring of a state of a hydraulic oil system, the monitoring system comprising:a hydraulic oil inlet configured to couple to the hydraulic oil system;
a hydraulic oil outlet configured to couple to the hydraulic oil system;
a hydraulic circuit disposed between the hydraulic oil inlet and the hydraulic oil outlet, such that, during operational use of the hydraulic oil system, hydraulic oil of the hydraulic oil system flows from the hydraulic oil system via the hydraulic oil inlet to the monitoring system, and then through the hydraulic circuit of the monitoring system and then back to the hydraulic oil system via the hydraulic oil outlet;
at least one sensor unit disposed in the hydraulic circuit, wherein the at least one sensor unit is configured for measuring at least one property of the hydraulic oil within the hydraulic circuit in operational use of the monitoring system, and
a processor unit configured to read out at least one output of the at least one sensor unit and to determine a condition of the hydraulic oil running through the hydraulic circuit, wherein the processor unit is further configured to determine a representative of a state of the hydraulic oil system based upon the condition of the hydraulic oil and further configured to couple to a display device for displaying the representative.

US Pat. No. 10,113,563

HYDRAULIC DRIVE AND METHOD FOR DISCREETLY CHANGING THE POSITIONAL OUTPUT OF SAID DRIVE

Linz Center of Mechatroni...

1. Method for discrete changing of a position output on a hydraulic drive, in which methodat least one displacer cylinder incrementally either supplies to or discharges from the drive its displacer volume, as a function of at least one input signal, via relocation of its piston element from a starting position into an end position, wherein the piston element of the displacer cylinder is relocated multiple times from the starting position into the end position and from this end position back again, in order to discretely change the position output on the drive in accordance with the displacer volume supplied or discharged,
wherein during relocation of the piston element from the starting position into the end position, the displacer cylinder is hydraulically connected with a feed line or return line of a pressure medium source,
and in a subsequent step, the changed position output on the drive is reset again,whereinwhen the piston element is relocated from the end position into the starting position, cylinder chambers of the displacer cylinder are hydraulically short-circuited by way of a short-circuit line that is hydraulically separated from the feed line or return line of the pressure medium source.

US Pat. No. 10,113,549

MONITORING AN ELECTRIC SUBMERSIBLE PUMP FOR FAILURES

SCHLUMBERGER TECHNOLOGY C...

1. A method for monitoring an electric submersible pump, comprising:acquiring a baseline signature for the electric submersible pump in a first environment while the electric submersible pump is confirmed to be healthy;
acquiring a downhole signature for the electric submersible pump in a downhole environment while the electric submersible pump is confirmed to be healthy;
applying an operator to the baseline signature and the downhole signature that results in a downhole noise component;
acquiring a vibration signature for the electric submersible pump in the downhole environment while the electric submersible pump is in an operating mode;
removing the downhole noise component from the vibration signature to produce an isolated electric submersible pump signature; and
determining a health status of the electric submersible pump based on the isolated electric submersible pump signature.

US Pat. No. 10,113,548

COMBINATION OF MOTOR AND VACUUM PUMP WITH AN EXHAUST FLOW

Gebr. Becker GmbH, Wuppe...

1. A vacuum device for generating a vacuum, the vacuum device comprising:a vacuum pump comprising:
a pump housing enclosing a pump shaft,
an air intake device connected with the pump housing, and
an air exhaust device connected with the pump housing, and
a motor acting upon the pump shaft for driving the vacuum pump,
wherein operation of the vacuum pump sucks in air via the air intake device for generating the vacuum,
wherein operation of the vacuum pump discharges exhaust air via the air exhaust device,
wherein the air exhaust device comprises a discharge valve,
wherein the exhaust air is, downstream of the discharge valve, divided into two partial flows that are respectively associated with a first pipe section and a second pipe section,
wherein the discharge valve is arranged above the motor and the vacuum pump relative to a normal operating state of a combination of the motor and the vacuum pump,
wherein the first pipe section conveys the exhaust air from a region above the motor and the vacuum pump into a region underneath the motor and the vacuum pump and is connected to the discharge valve, and
wherein the first pipe section is partially or completely arranged within an outside contour of at least one of the motor and the vacuum pump relative to a cross section perpendicular to a longitudinal axis of at least one of the motor and the pump shaft.

US Pat. No. 10,113,545

METHOD OF MANUFACTURING A SCREW PUMP WITHOUT UNDERCUT AND/OR SCREW PUMP WHICH CAN HAVE LUBRICATION CHANNELS ON AT LEAST ONE OF THE DRIVE SCREW AND RUNNING SCREWS

SKF Lubrication Systems G...

1. A method for manufacturing a screw pump for transporting a fluid, the method comprising the steps of:providing a drive spindle having a drive spindle profile,
providing a running spindle,
rolling a running spindle profile into the running spindle such that the running spindle profile is formed without undercut,
simultaneously with the rolling of the running spindle profile into the running spindle also forming a lubricant groove in the running spindle, and
wherein the running spindle engages with its running spindle profile at least partially in the drive spindle profile of the drive spindle.

US Pat. No. 10,113,543

FINGER TYPE PERISTALTIC PUMP COMPRISING A RIBBED ANVIL

Q-CORE MEDICAL LTD., Pet...

1. An interface configured to be placed in conjunction with a finger-type peristaltic pump including a plurality of fingers, said pump having a pumping cycle of alternating linear motion of each finger, said interface comprising:a conduit having a compressible segment and positioned within said interface such that when said interface is mounted on the pump the alternating linear motion of the fingers causes fluid to flow through the conduit by applying a series of compressive forces on said conduit, thereby defining a set of contact points on the conduit where fingers of the pump contact the conduit during the alternating linear motion of the fingers;
a conduit accommodation configured to receive said conduit and removably mount said interface to the finger type peristaltic pump;
and
a ribbed anvil positioned within said interface so as to contact a first surface of said conduit opposite a second surface of the conduit contacted by the fingers and having a longitudinal dimension perpendicular to the linear motion of the fingers, said ribbed anvil comprising:
(i) a first set of protruding ribs positioned directly across from each of the contact points, each of said first set of ribs having a flat surface perpendicular to the linear motion of the fingers configured to provide a counterforce to a compressive force produced by each of the plurality of fingers, when said interface is mounted to the pump; and
(ii) a second set of protruding ribs positioned such that the ribs of said second set of ribs alternate with the ribs of said first set of ribs, and such that the ribs of said second set of ribs are positioned to interface with the first surface of said conduit opposite the second surface of the conduit contacted by the fingers in between said contact points wherein said second set of ribs is configured to support the conduit when compressed.

US Pat. No. 10,113,541

VALVES AND PUMPS USING SAID VALVES

SILGAN DISPENSING SYSTEMS...

1. A valve for a pump, comprising:a valve stem;
an outlet valve at a first end of the valve stem;
a valve disc at a second end of the valve stem, the valve disc having a substantially flexible semispherical shape configured to collapse; and
at least one longitudinal rib running a portion of the length of the valve stem between the outlet valve and the valve disc,
wherein proximate the second end, the at least one longitudinal rib tapers inward towards the valve stem as the rib extends in a direction from the first end towards the second end.

US Pat. No. 10,113,539

CONTROL VALVE FOR VARIABLE DISPLACEMENT COMPRESSOR

TGK CO., LTD., Tokyo (JP...

1. A control valve for a variable displacement compressor, for varying a discharging capacity of the compressor for compressing refrigerant introduced into a suction chamber and discharging the compressed refrigerant from a discharge chamber, by regulating a flow rate of refrigerant introduced from the discharge chamber to a control chamber, the control valve comprising:a body having a main passage through which the discharge chamber and the control chamber communicate with each other, and a sub-passage through which the control chamber and the suction chamber communicate with each other;
a main valve seat provided in the main passage;
a main valve element configured to touch and leave the main valve seat to close and open a main valve;
a sub-valve seat provided in the sub-passage;
a sub-valve element configured to touch and leave the sub-valve seat to close and open a sub-valve;
a solenoid configured to generate a drive force in a valve closing direction of the main valve;
an actuating rod for transmitting the drive force of the solenoid to the main valve element and the sub-valve element;
a first biasing member for applying a biasing force to the main valve in a valve opening direction; and
a second biasing member for applying a biasing force to the sub-valve in a valve closing direction;
wherein the sub-valve is configured to open when a pressure difference between a control pressure in the control chamber and a suction pressure in the suction chamber becomes a preset pressure difference or larger.

US Pat. No. 10,113,535

DISPATCHABLE COMBINED CYCLE POWER PLANT

1. A combined cycle electric power plant comprising:a combustion turbine generator that combusts fuel to generate electricity and produce hot exhaust gases;
a second heat source other than the combustion turbine;
a thermal energy storage system that stores heat transferred from the second heat source;
a steam turbine generator that expands superheated steam across a steam turbine to generate electricity;
a first boiler; and
a superheater;
wherein the combined cycle electric power plant has a first mode of operation in which the superheated steam is produced by heating condensate from the steam turbine generator primarily with heat from the combustion turbine exhaust gases to produce hot liquid feedwater, boiling the hot liquid feedwater in the first boiler with heat primarily from the second heat source, from the thermal energy storage system, or from the second heat source and the thermal energy storage system to produce steam, and superheating the steam in the superheater primarily with additional heat from the combustion turbine exhaust gases.

US Pat. No. 10,113,527

SPARK PLUG TESTING KIT

John Leeson, Castle Hill...

1. A spark plug testing kit comprising:a spark observation device having a transparent observation chamber for viewing a spark gap of a spark plug installed therein in use;
positive and earth leads for electrically connecting the spark observation device at respective proximal ends thereof; and
a spark plug opening engaging device, wherein:
the spark plug opening engaging device is
elongate;
defines threading at a first end thereof for turning into a spark
plug opening of an engine block; and
defines an elongate electrical connector nut at a second end thereof, opposite the first end, where a side member spans between the first end and the second end;
a distal end of the earth lead comprises an electrical connector configured for engagement over the elongate electrical connector nut and having an insulative sheath thereabout; and
the spark plug opening engaging device defines at least one engine depressurisation exhaust port through the side member of the spark plug opening engaging device, the depressurisation exhaust port permitting flow of fluid from inside the spark plug opening engaging device to outside the spark plug opening engaging device.

US Pat. No. 10,113,510

VALVE FOR METHANE IN AUTOMOTIVE SYSTEMS WITH BY-PASS SYSTEM OF THE EXCESS FLOW BLOCKING DEVICE

OMB SALERI S.p.A., Bresc...

1. Valve for controlling flow of methane in automotive systems, the valve being adapted for a tank and comprising:a valve body including a tank duct ending in at least one main aperture, an entry duct, a delivery duct and a discharge duct;
a thermal safety device, operating between the tank duct and the discharge duct and normally closed to obstruct passage of methane between the tank duct and the discharge duct, adapted to switch to an open configuration if external temperature exceeds a predefined threshold value;
a blocking device, operating upstream of the delivery duct, adapted to switch to a closed configuration in which the blocking device chokes the passage of methane towards the delivery duct if the flow of methane exceeds a predefined threshold value, and normally open, the blocking device being positioned upstream of the main aperture of the tank duct;
a feed duct fluidically separate from the tank duct, connectable downstream with the delivery duct;
wherein the blocking device is operative upstream of the feed duct and is responsive to the flow of methane through the feed duct, and
wherein the feed duct comprises a by-pass duct inside the tank duct.

US Pat. No. 10,113,504

ALUMINUM CYLINDER BLOCK AND METHOD OF MANUFACTURE

GM GLOBAL TECHNOLOGIES LL...

1. A method of manufacturing a cylinder block having a shared cylinder bore wall with a portion of the shared cylinder bore wall including a metal matrix composite, the method comprising:providing a preform of a compacted powder;
disposing the preform into a prescribed position of a sand core tool cavity;
depositing a sand and resin mixture into the sand core tool cavity, curing the sand and resin mixture into a cured sand core, and removing the cured sand core from the tool cavity;
assembling the cured sand core into a sand core assembly and placing the sand core assembly into a mold;
pouring an aluminum alloy into the mold to form the cylinder block;
cleaning the cylinder block after allowing the aluminum alloy to solidify; and
executing a friction stir process for mixing the preform with a portion of the aluminum alloy that is adjacent to the preform to form a metal matrix composite.

US Pat. No. 10,113,490

CONTROL APPARATUS FOR INTERNAL COMBUSTION ENGINE

HONDA MOTOR CO., LTD., T...

1. A control apparatus for an internal combustion engine that includes a variable intake cam phase mechanism of a hydraulically-driven type for changing an intake cam phase which is a phase of an intake cam for opening and closing an intake valve with respect to a crankshaft, and a variable exhaust cam phase mechanism of a hydraulically-driven type for changing an exhaust cam phase which is a phase of an exhaust cam for opening and closing an exhaust valve with respect to the crankshaft, the control apparatus controlling the intake cam phase and the exhaust cam phase via the variable intake cam phase mechanism and the variable exhaust cam phase mechanism, comprising:intake-side cleaning control means for performing intake-side cleaning control that controls the intake cam phase to be advanced such that a valve overlap period of the intake valve and the exhaust valve is increased;
exhaust-side cleaning control means for performing exhaust-side cleaning control that controls the exhaust cam phase to be retarded such that the valve overlap period of the intake valve and the exhaust valve is increased; and
selection inhibition means for selecting one of the intake-side cleaning control by said intake-side cleaning control means and the exhaust-side cleaning control by said exhaust-side cleaning control means so as to cause the one to be performed, and inhibiting the other thereof, according to an operating state of the engine.

US Pat. No. 10,113,470

AFTER TREATMENT DEVICE OF EXHAUST SYSTEM FOR VEHICLE

HYUNDAI MOTOR COMPANY, S...

1. An after treatment device of an exhaust system for a vehicle connected to an exhaust pipe and including a canning main body in which a catalyst is received, comprising:a heat insulation coating layer formed on an inner wall surface of the canning main body,
wherein the canning main body encloses an outer side surface of a catalyst support member that supports the catalyst and has the heat insulation coating layer formed on a corresponding inner wall surface thereof at a predetermined distance from the outer side surface of the catalyst support member,
wherein the heat insulation coating layer includes an inorganic binder that includes two or more silicon-based compounds and aerogel dispersed therein, such that the inorganic binder comprises 5 to 50 parts by weight of the aerogel for 100 parts by weight of the inorganic binder,
wherein the two or more silicon-based compounds are silanols and silicates with a weight ratio of 2 to 10, respectively,
wherein the inorganic binder exhibits a heat conductivity of 1.0 W/mK or less.

US Pat. No. 10,113,466

SYSTEM FOR TREATING THE EXHAUST GASES FOR A VEHICLE EQUIPPED WITH INTERNAL COMBUSTION ENGINE

SDF S.p.A., Treviglio (I...

1. Vehicle (12) in combination with an internal combustion engine (14), the internal combustion engine (14) comprising:a fly-wheel (24) placed at a rear part with respect to the internal combustion engine (14);
a cooling system (28) placed at a front part with respect to the internal combustion engine;
a forced induction group consisting of a turbine (22), placed on the same side of the fly-wheel (24), and of a compressor (30), placed on the same side of the cooling system (28); and
a system (10) for treating exhaust gases provided with a conduit (18) for the inlet of exhaust gases, operatively connected to an exit door of the turbine (22), a conduit (20) for the outlet of exhaust gases and a main body or shell (38) internally hollow for containing a substrate (44) through which the exhaust gases are conveyed so that they are subject to predefined chemical reactions,wherein said system (10) for treating exhaust gases is placed on a head of the internal combustion engine (14), wherein said main body or shell (38) has a cross-sectional shape, with respect to the driving direction of the vehicle (12), an ellipsoid the larger axis of which is oriented according to a substantially horizontal direction and the smaller axis of which is oriented according to a substantially vertical direction, so that said main body or shell (38) has a widened and compressed shape that allows it to occupy the least height-wise possible space with respect to the head of the internal combustion engine (14), and wherein said conduit (18) for the inlet of exhaust gases and said conduit (20) for the outlet of exhaust gases are placed in fluid communication with a same transverse side wall (46), with respect to the driving direction of the vehicle (12), of said main body or shell (38).

US Pat. No. 10,113,464

METHOD AND APPARATUS FOR CONTROLLING REDUCTANT INJECTION INTO AN EXHAUST GAS FEEDSTREAM FROM AN INTERNAL COMBUSTION ENGINE

GM Global Technology Oper...

1. An exhaust aftertreatment system configured to purify an exhaust gas feedstream for an internal combustion engine, comprising:first and second selective catalytic reduction devices (SCRs), wherein the first SCR is disposed upstream relative to the second SCR;
a reductant injection system disposed to inject reductant into the exhaust gas feedstream upstream relative to the first SCR;
a first temperature sensor disposed to monitor a first temperature of the exhaust gas feedstream upstream relative to the first SCR;
a second temperature sensor disposed to monitor a second temperature of the exhaust gas feedstream upstream relative to the second SCR; and
a controller operatively connected to the reductant injection system and in communication with the first and second temperature sensors and the internal combustion engine,
wherein the controller includes an instruction set that is executable to:
determine a total ammonia storage capacity for the first and second SCRs;
determine an ammonia storage level on the first SCR and an ammonia storage level on the second SCR;
determine a total SCR ammonia storage level for the first and second SCRs based upon the ammonia storage level on the first SCR and the ammonia storage level on the second SCR;
determine a first storage error based upon the total ammonia storage capacity for the first and second SCRs and the total SCR ammonia storage level for the first and second SCRs;
determine a second storage error based upon an ammonia storage level for the second SCR and an ammonia storage capacity for the second SCR;
determine a first reductant dosing rate based upon the first storage error;
determine a second reductant dosing rate based upon the second storage error; and
control the reductant injection system to inject reductant into the exhaust gas feedstream based upon the second reductant dosing rate when the second storage error indicates an imbalance between the ammonia storage on the first SCR and the ammonia storage on the second SCR.

US Pat. No. 10,113,425

UNDERGROUND MINING SYSTEM FOR REDUCED COSTS, IMPROVED EFFICIENCIES, HIGHER PRODUCTIVITY AND A SAFER WORKING ENVIRONMENT THROUGH PENETRATED BLOCK EXTRACTION

Underground Extraction Te...

1. An underground mining method including the steps of forming:forming one or more sets of underground gate roads, each set of gate roads including at least two headings; and
forming underground dead-end plunge cuts extending from the sets of gate roads, each plunge cut formed with an unmanned continuous miner coupled to a flexible conveyor system and being greater than 30 meters in length with a roof that need not be supported;
sealing each dead-end plunge cut to form a ventilation barrier whilst still permitting entry of the continuous miner coupled to a flexible conveyor system; and
supplying inert gas to a cutting face of each plunge cut.

US Pat. No. 10,113,420

ROTARY PULSERS AND ASSOCIATED METHODS

GEO TREND CORPORATION, H...

1. A rotary pulser for a downhole telemetry system configured to be positioned in a drill string within a wellbore, the rotary pulser configured to generate pressure pulses in a drilling fluid, the rotary pulser comprising:a housing,
a stator disposed within the housing,
a rotor disposed adjacent to the stator within the housing, and
an electrohydraulic drive disposed within the housing for rotating the rotor relative to the stator, the electrohydraulic drive comprising:
a pump with a regulator mechanism,
an actuation mechanism,
an electric motor, and
a control unit,
wherein, based on a parameter or condition associated with the rotary pulser, the regulator mechanism adjusts a parameter of the pump to control rotation of the rotor; and
wherein the actuation mechanism comprises a cylinder block, a valve disposed within the cylinder block, pistons and a cam, the cam defines ramp profiles including rolling surfaces along which piston heads of the pistons move, and the ramp profiles of the cam impart varying degrees of forces on the piston heads as the pistons move along the rolling surfaces.

US Pat. No. 10,113,415

METHODS AND APPARATUSES FOR DETERMINING TRUE VERTICAL DEPTH (TVD) WITHIN A WELL

Arthur H. Kozak, Edmonto...

1. A method of determining true vertical depth (“TVD”), within a well penetrating a ground surface, the method comprising:positioning a tubing string downhole such that a pressure sensor, located within an interior of the tubing string, is located at a base downhole position within the well at a base of a fluid column extended from a ground surface to the pressure sensor within the tubing string;
measuring, with the pressure sensor, or a plurality of pressure sensors that include the pressure sensor, a plurality of pressures exerted by the fluid column, in which the pressure is measured by the pressure sensor, or the plurality of pressure sensors, while fluid in the fluid column is stationary;
measuring a temperature of fluid in the fluid column at each of a series of positions to generate a series of temperature measurements, each associated with a respective position, of the series of positions, along the fluid column, in which the series of temperature measurements are taken while fluid in the fluid column is stationary;
generating a density profile of fluid along the fluid column based on the series of temperature measurements; and
determining the TVD of the base downhole position using the density profile of fluid along the fluid column to correct for density changes of fluid along the fluid column, and using the plurality of pressures measured by the pressure sensor or the plurality of pressure sensors.

US Pat. No. 10,113,386

APPARATUS FOR USE IN WELL ABANDONMENT

BiSN Tec Ltd., Lymm (GB)...

1. A plugging system for plugging wells, and in particular oil and gas wells, said plugging system comprising a plug body formed from an outer metal tube and an inner metal tube, wherein the tubes are concentric;reinforcement means, attached to an inner surface of the outer tube and attached to an outer surface of the inner tube, thereby connecting the inner and outer tubes and thereby providing cross-sectional structural strength to the plug body; and
wherein an upper end of the plug body has a central heater receiving void located along the axis of the plug, wherein the void is defined by an inner surface of the inner tube; and a lower end of the plug body having a base extending across the entire plug body and to which both the inner and outer tubes are connected.

US Pat. No. 10,113,373

CENTRALISER

INNOVEX DOWNHOLE SOLUTION...

1. A composite centraliser comprising:an elongate non-cylindrical housing having an arcuate surface, wherein first and second recesses are defined in an inside of the arcuate surface, the first and second recesses being axially spaced on the elongate non-cylindrical housing, and
an elongate resilient member having first and second ends, wherein the first and second ends are located in the respective first and second recesses of the elongate non-cylindrical housing, such that the first end is retained in the first recess at least partially by engagement with the inside of the arcuate surface in the first recess, and wherein a surface of the elongate resilient member is outwardly spaced from the elongate non-cylindrical housing,
wherein the elongate non-cylindrical housing has a longitudinal slot extending through the arcuate surface and between the first and second recesses, wherein, as proceeding from the first end, the elongate resilient member extends outward through the slot, projects outwardly from the elongate non-cylindrical housing, and extends inward through the slot to the second end.

US Pat. No. 10,113,369

CUTTING ASSEMBLY FOR A BORING DEVICE

Barbco, Inc., East Canto...

16. A method comprising steps of:providing a cutting assembly comprising a first cutting head and a second cutting head; wherein the second cutting head is spaced a distance rearwardly behind the first cutting head;
providing a pilot tube within an underground pilot hole having a pilot hole diameter; wherein the borehole follows the pilot hole and has a borehole diameter larger than the pilot hole diameter; and
engaging the cutting assembly and the pilot tube in end-to-end relationship;
engaging the pilot tube with a front end of a shaft of the cutting assembly;
placing a bore of the pilot tube in fluid communication with a bore of the shaft;
moving pressurized air through the bore of the pilot tube into the bore of the shaft;
rotating and moving forward the cutting assembly and a casing extending rearwardly from the cutting assembly to cut an underground borehole;
moving the pressurized air from the bore of the shaft through a first air passage formed in the first cutting head and through a second air passage formed in the second cutting head; and subsequently moving the pressurized air into a bore defined in the casing to discharge cuttings created by the first and second cutting heads out of the casing; and
wherein the step of moving pressurized air through the bore of the shaft further comprises creating backpressure in the bore of the shaft.

US Pat. No. 10,113,365

DRILL BIT FOR MILLING COMPOSITE PLUGS

HIJET BIT LLC, Norman, O...

1. A roller cone drill bit comprising:a body having a central axis, around which it is to be rotated, and a coupling for connecting the body to a drill string or coiled tubing; and
at least a first and a second roller cone, each of which is mounted for rotation about a bearing axis extending from the body at an angle oblique to the central axis and has a heel portion and an inner portion between the heal portion and central axis, each of the first and second roller cones having surface on which is disposed a plurality of cutting elements, the plurality of cutting elements arranged on a surface in a plurality of rows comprising at least a first row and a second row that are each concentric with the bearing axis, with one of the first and second rows located closer to the central axis than the other;
wherein the first row on the first roller cone is comprised of groups of one more milled steel teeth alternating with groups of one or more cemented metal carbide inserts, wherein each of cemented carbide inserts has a cutting depth that is equal to or greater than each of the plurality of milled steel teeth in the first row.

US Pat. No. 10,113,363

SYSTEM AND RELATED METHODS FOR CONTROL OF A DIRECTIONAL DRILLING OPERATION

APS Technology, Inc., Wa...

18. A method for controlling a direction of a drill bit coupled to a drill string, the method comprising the steps of:causing the drill bit to drill a borehole into the earthen formation along a predetermined drilling direction;
guiding the drill bit with a rotary steerable motor system according to one or more steering parameters toward the predetermined drilling direction during formation of the borehole in response to any determined deviations between an actual drilling direction and the predetermined drilling direction; and
correcting the steering parameters based on one or more operational parameters of the rotary steerable system, wherein the one or more operational parameter is a differential pressure of a pump in the rotary steerable motor system.

US Pat. No. 10,113,362

OFFSET SHAFT BEARING ASSEMBLY

TURBO DRILL INDUSTRIES, I...

1. An offset shaft bearing assembly for a downhole tool comprising:an outer housing, the outer housing having a housing centerline;
a drive shaft, the drive shaft extending through the outer housing, the drive shaft being generally tubular and having a shaft centerline; and
two or more radiused conical bearings positioned to couple the drive shaft to the outer housing, each radiused conical bearing having:
an outer surface, the outer surface being generally cylindrical, the outer surface coupled to the outer housing and aligned with the housing centerline;
an inner surface, the inner surface being generally cylindrical, the inner surface coupled to the drive shaft and aligned with the shaft centerline;
a first bearing surface, the first bearing surface coupled to the outer surface of the bearing; and
a second bearing surface, the second bearing surface coupled to the inner surface of the bearing, the bearing surfaces radiused such that the bearing surfaces remain in contact despite angular misalignment between the outer surface and the inner surface;
wherein at least one radiused conical bearing is offset from the housing centerline in a direction perpendicular to the housing centerline such that the shaft centerline is at an angle to the housing centerline.

US Pat. No. 10,113,357

DOOR ASSEMBLY

THERMA-TRU CORPORATION, ...

1. A door assembly, comprising:a door frame including a first side section, a second side section, and a sill section;
a door pivotably connected to the door frame by a hinge such that the door is pivotable between an open position and a closed position, the door including a first edge surface and a second edge surface, wherein the second edge surface faces the sill section;
wherein the door further comprises a first rounded corner between the first edge surface and the second edge surface and the door frame further comprises a second rounded corner between the first side section and the sill section;
wherein a door seal is attached to the door along the first edge surface, the rounded corner, and the second edge surface and a frame seal is attached to the door frame along the first side section, the rounded corner, and the sill section;
wherein the door seal includes a first flat surface facing the door, and a first convex curved surface facing away from the door, the first convex curved surface including a first substantially flat and sloped surface, and a first rounded surface joined with the first sloped surface at an apex of the first convex curved surface, and the frame seal includes a second flat surface facing the door frame, and a second convex curved surface facing away from the door frame, the second convex curved surface including a second substantially flat and sloped surface, and a second rounded surface joined with the second sloped surface at an apex of the first convex curved surface, connecting the second flat surface to the second sloped surface; and
wherein, the first sloped surface engages the second sloped surface when the door is in the closed position.

US Pat. No. 10,113,345

COVER OF INSPECTION CHAMBER

ROMBA DRYWALL CZ S.R.O., ...

1. A cover system for an inspection chamber, the system comprising:a door comprising a magnetically conductive material;
a fixture that comprises at least one of an “L” shaped and a “U” shaped object, the at least one of the “L” shaped object and the “U” shaped object each comprising a front arm; and
a magnet that is coupled to and disposed on the front arm,
wherein the fixture is configured to couple to a wall at an opening in the wall,
wherein a perimeter of the door is at least partially defined by a welt, which extends from a portion of the door by a distance that is substantially equal to a sum of a height of the front arm and the magnet, and
wherein the magnet on the front arm is configured to magnetically couple to, and to selectively decouple from, the door in a plurality of different locations disposed within the perimeter defined by the welt.

US Pat. No. 10,113,343

THERMALLY ISOLATED HIGH INTENSITY LIGHT SOURCE

Surna Inc., Boulder, CO ...

1. A high intensity discharge light source comprising:a bulb having:
a first end;
a second end;
a central region extending between said first end and said second end in a longitudinal direction; and
an outer surface extending between said first end and said second end;
a thermally insulative and optically transparent sleeve having an inner surface, said sleeve longitudinally aligned with and separated from said bulb outer surface by an insulating distance;
a first spacer positioned adjacent to said bulb first end and between said bulb outer surface and said sleeve inner surface;
a second spacer positioned adjacent to said bulb second end and between said bulb outer surface and said sleeve inner surface; wherein:
said first spacer and said second spacer provides said insulating distance between said bulb outer surface and said sleeve inner surface, thereby forming an insulative volume around said bulb; and
during use said bulb and surrounding insulative volume reach an elevated steady state operating temperature to maintain or enhance a spectral performance parameter.

US Pat. No. 10,113,317

APPARATUS AND METHOD FOR HANGING ARCHITECTURAL PANELS WITH CONCEALED ATTACHMENT POINTS

Gordon Sales, Inc., Boss...

9. A panel anchoring system comprising:a) a latching assembly comprising:
i) a base bracket, the base bracket comprising first and second projecting walls; and
ii) a resilient beam movably coupled to the base bracket so as to allow the resilient beam to deflect, wherein the resilient beam is a sinusoidal-shaped wire spring comprising a first leg and a second leg, wherein the first leg of the sinusoidal-shaped wire spring is movably coupled to a first elongated hole in the first projecting wall, and wherein the second leg of the sinusoidal-shaped wire spring is movably coupled to a first elongated hole in the second projecting wall; and
b) a panel comprising a keyed flange, the keyed flange comprising:
i) first and second locking slots configured for releasable attachment to the first and second legs of the sinusoidal-shaped wire spring; and
ii) first and second ramps, with the first ramp being positioned adjacent to the first locking slot, and with the second ramp being positioned adjacent to a second locking slot.

US Pat. No. 10,113,310

COATING MATERIAL FOR ACHIEVING SOUND-DAMPENING AND METHOD FOR THE SAME

Blue Angel Paint and Coat...

1. A sound-dampening coating material comprising:a base coat material having an applied thickness in the range of from about 25 to about 30 mil, the base coat material having the following formula:
20 to 40 percent by weight of a rubber emulsion; about 10 to about 20 percent by weight of a carbonate filler; about 3 to about 10 percent by weight of a fire retardant; about 3 to about 10 percent by weight of an opacity filler; and
about 10 to about 64 percent by weight of other components for affecting characteristics of the base coat material;
a top coat material applied over the base coat material to a thickness in the range of from about 7 to about 10 mil, the top coat material having the following formula:
about 40 to about 80 percent by weight of a rubber emulsion; about 10 to about 20 percent by weight of a carbonate filler; about 3 to about 10 percent by weight of a fire retardant; about 3 to about 10 percent by weight of a opacity filler; and
about 0 to about 44 percent by weight of other components for affecting characteristics of the top coat material.

US Pat. No. 10,113,309

FLOOD VENT BARRIER SYSTEMS

Smart Vent Products, Inc....

1. A vent barrier system comprising:an insert comprising side faces extending between a first end and a second end of the insert, wherein the insert is dimensioned to be inserted within a flood vent duct through a first opening such that the side faces contact sidewalls of the duct and provide an insulative seal between the first opening and a second opening of the duct when inserted therein;
a cover having a first side and a second side configured to be attached to the first face of the insert, wherein the cover is dimensioned to be selectively securable to the duct at the first opening, wherein the cover is manipulatable to selectively remove the insert from the duct; and
a door positioned at the second opening of the duct;
wherein the insert is dimensioned to extend within the duct and prevent the door positioned at the second opening of the duct from opening in a first direction when inserted therein, wherein the insert is dimensioned such that a second face is located adjacent to the door when inserted within the duct to prevent the door from moving from a closed position to an open position, wherein the door is configured to open in a second direction when the insert is inserted therein.

US Pat. No. 10,113,308

EXPANSION JOINTS

Underwood Companies Holdi...

1. An expansion joint applied to a layer applied to a substrate, the joint having a first strip extending on one side of the joint and a second strip extending on the other side of the joint, an upper surface plate of the first strip being adapted to extend across the joint, and being disposed to move across the joint, the strips being mutually aligned for relative movement while maintaining the upper surface of the first strip in a predetermined plane relative to the second strip;wherein the first and second strips comprise mutually aligned male and female cooperating parts, the male part comprising a male strip, the female part carrying the upper surface plate and comprises a channel extending along the first strip and the joint includes one or more seals between the strips and a seal receiving formations adapted to retain said one or more seal, said formation comprising tapered edge rebates of opposite corners of a free edge of the male strip and holding a matching seal strip scaling the first and second strips.

US Pat. No. 10,113,305

LOAD BEARING INTERLOCKING STRUCTURAL BLOCKS AND TENSIONING SYSTEM

JUST BIOFIBER STRUCTURAL ...

1. A structural panel assembled of structural blocks with a tensioning system for contributing to lateral load bearing attributes of the panel, comprising:a plurality of structural blocks, each structural block having opposed pin and aperture surfaces, opposed side surfaces and opposed end surfaces;
a plurality of load-bearing structural strut members embedded within each structural block, a pin end of each strut member extending from a pin surface of the structural block, wherein one or more of the embedded strut members comprises a lengthwise cavity therethrough;
a plurality of apertures extending within the structural block from the aperture surface opposite the pin surface of the structural block each of the apertures adapted for engaging with an extending pin end of a structural strut member of an adjacent structural block which then places an end of a structural strut member of the structural block adjacent to an end of a structural strut member of the adjacent structural block, each strut member extending a distance from a block's one surface and being positioned retracted by a like distance from the same blocks' opposite surface, the space from the retracted strut end to the block's surface being the aperture;
the stacked structural blocks causing the structural struts to also be stacked end-to-end through the panel formed by the stacked blocks, forming:
structural columns of structural strut members aligned to form compression load-bearing internal columns inside the panel;
conduits from one edge at a pin side of an outer block of the panel to the opposite edge of the panel at the aperture side of an aligned outer block of the panel to receive and accommodate tensioning means, the conduits comprised of lengthwise cavities within a column of stacked structural struts within the panel; and
tensioning means positioned within the lengthwise conduits formed of the cavities of one or more embedded end-to-end adjacent strut members, wherein the cavities in the embedded strut members of end-to-end adjacent structural blocks align to form the conduit for receiving the tensioning means, the tensioning means within the assembled panel under tension;
the structural struts aligned within each block in parallel pairs, one strut of each pair parallel to and nearer to one side of the block and the other strut of the same pair parallel to and nearer to the opposite side of the block;
the apertures and protruding pin ends on the aperture surface and the pin surface, respectively, arrayed to easily align blocks to be stacked, the pins and apertures providing block self-alignment guides for assembly of blocks to form the panel; and
the blocks within the panel further comprising a connecting web situated and embedded in the body of the structural blocks in between two strut members of a pair of strut members, the web being perpendicular to the longitudinal axis of the block and attached to both strut members of the pair of strut members.

US Pat. No. 10,113,303

COVER ASSEMBLY FOR A FLOOR DRAIN

Drain Dome LLC, Roanoke,...

1. A cover assembly for a drain comprising:a saucer-shaped cover body having a first side for facing toward a drain opening in a surface having a drain pipe and a second side for facing away from the drain opening, the saucer-shaped cover body defining a plurality of flow passages extending between said first side and said second side so as to allow a liquid to pass through the cover body to the drain opening, at least a portion of the second side of the saucer-shaped cover body having a corrugated configuration formed by adjacent grooves and ridges, said grooves and ridges cooperating to facilitate reduction in blockage of said flow passages by debris on said second side of said saucer-shaped cover body; and
an anchor having a stem and deformable insert structure having a width diameter greater than the internal diameter of said drain pipe, said stem being removably attachable to said saucer-shaped cover body so as to depend from said first side thereof, and said insert structure including a pair of split fork loops at a distal end thereof sized to deform inwardly when inserted into the drain pipe and cause the insert structure to exert pressure on and frictionally engage the internal wall of the drain pipe.

US Pat. No. 10,113,293

BUCKET FOR CABLE SHOVEL

ESCO Group LLC, Portland...

1. A cable shovel bucket comprising a shell and a door collectively defining a cavity for gathering material during operation of the cable shovel, the shell including a front wall, an opposite back wall and sidewalls extending between the front wall and the back wall, the back wall having an exterior surface that faces the cable shovel when the bucket is in a dumping position, the door being pivotally secured to the shell for gravity activated movement between an open position and a closed position about a pivot axis extending through the cavity between the exterior surface of the back wall of the shell and the front wall and including a restraint to selectively hold the door in the closed position.

US Pat. No. 10,113,289

FORMS AND SUBSURFACE STRUCTURAL ELEMENTS THAT REDIRECT SOIL FORCES

V-Forms, LLC, Cedar Park...

1. A form for constructing at least a portion of a structural foundation, the form comprising:one or more wall forming portions configured to shape a foundation material to form one or more respective walls of at least one subsurface structural element of the at least a portion of the structural foundation; and
one or more termination forming portions configured to shape the foundation material to form a corresponding termination portion of the at least one subsurface structural element such that the termination portion is adjacent to a bottom portion of at least one of the one or more respective walls, wherein the termination portion and the at least one wall meet at a non-zero angle greater than or less than 90 degrees,
wherein the termination portion is a lower most portion of the structural foundation; and
wherein the form is configured to shape, based at least in part on the one or more wall forming portions, the foundation material to form the at least one subsurface structural element such that:
the at least one subsurface structural element extends from a surface-level base of the structural foundation to a subsurface level; and
the at least one subsurface structural element is configured to redirect soil forces to vertically displace the structural foundation.

US Pat. No. 10,113,285

REVETMENT SYSTEM

Shoretec, LLC, Baton Rou...

1. A multi-layer revelment system adapted to be placed on top of a ground surface to inhibit its erosion, comprising:a cellular confinement layer comprising a matrix of rigid wall cells that are open across the height of the cells, wherein the height of the cells is about 1 to 12 inches,
an articulated block layer adapted to be placed on top of the cellular confinement layer on the opposite side of the cellular confinement layer than the ground surface, and
a permeable geosynthetic layer that is adapted to be placed on the ground surface and under the cellular confinement layer;
and wherein none of the layers are fixed to an adjacent layer.

US Pat. No. 10,113,280

AUTONOMOUS ROBOT APPARATUS AND METHOD FOR CONTROLLING THE SAME

Michael Todd Letsky, Boc...

1. An autonomous robot apparatus comprising:a chassis;
a plurality of wheels mounted to the chassis;
a drive system mounted to the chassis and operably coupled to the plurality of wheels;
a control module operably coupled to the drive system;
a precipitation sensing module comprising an accumulation cavity, wherein a floor of the accumulation cavity comprises at least one drainage aperture, an accumulation level sensor configured to generate and transmit, to the control module, a first signal upon a predetermined initial accumulation level of precipitation being detected, and wherein the predetermined initial accumulation level is an adjustable parameter that can be modified by an end user, wherein the accumulation level sensor comprises a plurality of sensors mounted on a wall of the accumulation cavity;
the control module configured to activate the autonomous robot apparatus to perform a first instance of a work routine upon receipt of the first signal;
the precipitation sensing module further configured to generate and transmit, to the control module, a second signal upon a predetermined secondary accumulation level of the precipitation being detected, the predetermined secondary accumulation level of the precipitation being a greater accumulation of the precipitation than the predetermined initial accumulation level of the precipitation;
the control module further configured to cause the autonomous robot apparatus to perform a second instance of the work routine, after completion of the first instance of the work routine, upon receipt of the second signal.

US Pat. No. 10,113,279

BARRIER SYSTEMS WITH PROGRAMMABLE LIGHT ASSEMBLY

Off The Wall Products, LL...

1. A method for using barrier systems, the method comprising:positioning a plurality of barrier systems at a location, each barrier system comprising:
a barrier having an interior surface and an opposing exterior surface, the interior surface bounding a chamber that is adapted to receive a ballast; and
a light assembly secured to the barrier, the light assembly comprising a housing having a lens that at least partially bounds a compartment, a light emitting device at least partially disposed within the compartment, and programmable circuity in electrical communication with the light emitting device;
communicating wirelessly with the programmable circuity of each barrier system through a control device after the barrier systems are positioned at the location so that data is transferred between the control device and the programmable circuity of each barrier system,
wherein the programmable circuity of each light assembly transfers data to the control device, the data comprising a temperature reading at each light assembly or an operational condition of each light assembly.

US Pat. No. 10,113,278

MODULE FOR DEICING A CABLE SHEATH AND METHOD FOR USING THE SAME

American Bridge Maintenan...

1. A module for placement inside a sheath having a longitudinal axis and for vibrating the sheath comprising a body having:a) a mass;
b) a vibrator attached to the mass;
c) a base supporting the mass and vibrator and adapted to contact an inner wall of the sheath; and
d) wherein the body has a tether attached thereto adapted for towing the body along the longitudinal axis of the sheath.

US Pat. No. 10,113,271

DECORATION AND ADORNMENT METHODS FOR THERMOFORMED PULP

VARDEN PROCESS PTY LTD, ...

1. A method of forming a molded and printed product from pulp material including the steps of:a) forming a wet pulp pre-form from the pulp material;
b) applying a dry or cured printing decoration ink membrane bespoke coating to said wet pulp pre-form using an intermediate transfer surface, being separate and distinct from said pre-form, to form a printed pre-form;
c) transferring the printed pre-form to a mold; and
d) molding or re-molding said printed pre-form to form said molded and printed product.

US Pat. No. 10,113,265

LAUNDRY SOCK/GARMENT SNARE

Laundry Loops, Inc., Boz...

1. A laundry snare for laundering a plurality of items, the laundry snare comprising:two elongated cord strands having:
a first end wherein the two cord strands are connected together; and
a second end wherein the two cord strands are connected together;
a plurality of loading regions located between the first and second ends formed by a plurality of stoppers positioned along a length of the two cord strands and securing the two cord strands together; and
a plurality of releasable cordlock fasteners placed between two of the plurality of stoppers and configured to be selectively located and secured between the two of the plurality of stoppers;
wherein the releasable cordlock fasteners are threaded through the two cord strands.

US Pat. No. 10,113,240

CATHODIC PROTECTION SYSTEM MONITORING

Stratocom Solutions Corpo...

1. A method for testing a cathodic protection system for a metallic structure that has associated therewith a first set of locations, each location of the first set of locations including a testing module, electrically connected to the metallic structure, and an associated reference electrode, the method comprising, for each location of the first set of locations:periodically, at a first frequency, interrupting power provided at each location of the first set of locations to cause power provided to the metallic structure to switch on and off a plurality of times over a testing time period;
measuring, by each testing module, DC voltage differentials between the metallic structure and its associated reference electrode when the power provided to the metallic structure is on and when the power provided to the metallic structure is off, at a plurality of times during a plurality of interruption cycles, wherein measuring DC voltage differentials between the metallic structure and its associated reference electrode when the power provided to the metallic structure is off is asynchronous to interrupting power to the metallic structure, and wherein initiation of each of the interruption cycles is independent of interrupting power provided at each location of the first set of locations;
storing in a digital storage medium at each testing module, digital values associated with the measured DC voltage differentials during the interruption cycles; and
providing at least selected digital values to a remotely located device upon request by the remotely located device.

US Pat. No. 10,113,230

FORMATION METHOD OF HEXAGONAL BORON NITRIDE THICK FILM ON A SUBSTRATE AND HEXAGONAL BORON NITRIDE THICK FILM LAMINATES THEREBY

KOREA INSTITUTE OF SCIENC...

1. A method of forming a multilayer hexagonal boron nitride (h-BN) thick film on a substrate, the method comprising:(a) a substrate heating step of heating a first substrate comprising iron (Fe);
(b) a h-BN precursor supply step of supplying h-BN precursors comprising borazine (H3B3N3H3) to the heated first substrate;
(c) a precursor dissolving step of dissolving the supplied h-BN precursors in the first substrate;
(d) a substrate cooling step of cooling the first substrate containing the dissolved h-BN precursors therein; and
(e) a formation step of multilayer h-BN thick film on a surface of the first substrate from the dissolved h-BN precursors therein.

US Pat. No. 10,113,142

METHOD AND APPARATUS FOR MAKING SOAP

DESIGNED BY M.E., LLC, B...

1. A method for making soap comprising:piercing, upon closure of a lid of an apparatus, a lye capsule in a lye container;
combining, in a first mixing vessel, a portion of water from a water vessel with a portion of lye from the lye capsule to form a first mixture;
cooling, in the first mixing vessel, the first mixture to a first predetermined temperature;
combining, in an oil vessel, two or more oils to dissolve into a second mixture;
heating, in the oil vessel, the second mixture to a second predetermined temperature to produce a heated second mixture;
adding, in the oil vessel, a third oil to the heated second mixture;
cooling, in the oil vessel, the heated second mixture to a third predetermined temperature to produce a cooled second mixture;
combining, in a second mixing vessel, the first mixture and the cooled second mixture to form a third mixture; and
discharging the third mixture from the second mixing vessel into one or more soap molds to form one or more bars of soap.

US Pat. No. 10,113,136

FRACTIONATION OF FRANKINCENSE RESIN USING SUPERCRITICAL CARBON DIOXIDE

PHYTOVATION LTD, Gwynedd...

1. A method for sequentially extracting essential oil, incensole derivatives and boswellic acid from frankincense resin, said method comprising:a) grinding the frankincense resin;
b) separating a first fraction of essential oil with liquid carbon dioxide at a first temperature ranging between 0° C. and 30° C. and a first pressure ranging between 40 bars and 73.8 bars or with mild supercritical carbon dioxide, and with a first flow rate ranging between 10 g and 400 g/kg ground material/min until no further essential oil can be recovered or the extract yield falls below 0.1% of starting mass per hour;
c) retrieving essential oil from the separator;
d) separating a second fraction of incensole derivatives with supercritical carbon dioxide at a second temperature ranging between 31° C. and 100° C. and a second pressure of at least 72.8 bars and a second flow rate ranging between 10 g and 400 g/kg ground material/min until no further incensole or its derivatives can be recovered or the extract yield falls below 0.1% of starting mass per hour;
e) retrieving incensole derivatives from the separator;
f) optionally, continuing the separation process with supercritical carbon dioxide at other sets of increasing temperature and/or pressure until further desired fractions are separated;
g) separating a further fraction of boswellic acid with supercritical carbon dioxide at a temperature of at least 31° C. and a pressure of at least 72.8 bars and a flow rate ranging between 10 g and 400 g/kg ground material/min using a co-solvent at a level ranging between 0.05 vol % and 50.0 vol % of the CO2 flowrate until complete separation of boswellic acids is achieved or it is determined that no further materials can be extracted or the extract yield falls below 0.1% of starting mass per hour;
h) retrieving boswellic acid from the separator and removing the co-solvent by evaporation or distillation;
i) optionally, continuing the separation process with supercritical carbon dioxide at another set of temperature and pressure and co-solvent until all desired fractions are separated; and
j) retrieving the remaining unseparated residues.

US Pat. No. 10,113,098

COMPOSITION INCLUDING VISCOSIFIER POLYMER AND POLYAMINE VISCOSITY MODIFIER FOR TREATMENT OF SUBTERRANEAN FORMATIONS

Halliburton Energy Serviv...

1. A composition for treatment of a subterranean formation, the composition comprising:a viscosifier polymer comprising
an ethylene repeating unit comprising an —NRa—C(O)—Rb group, wherein at each occurrence Ra and Rb are each independently selected from —H and substituted or unsubstituted (C1-C20)hydrocarbyl or Ra and Rb together form a substituted or unsubstituted (C2-C20)hydrocarbylene,
an ethylene repeating unit comprising an —S(O)2OR1 group wherein at each occurrence R1 is independently selected from —H, substituted or unsubstituted (C1-C20)hydrocarbyl, and a counterion,
at least one crosslinker repeating unit comprising an ethylene repeating unit at each occurrence independently linked to an ethylene repeating unit in the same viscosifier polymer molecule or in another molecule of the viscosifier polymer via a substituted or unsubstituted (C1-C40)hydrocarbylene interrupted by 0, 1, 2, or 3 groups independently chosen from —O—, —S—, and substituted or unsubstituted —NH—,
wherein the repeating units are in block, alternate, or random configuration; and
a polyamine viscosity modifier, wherein the polyamine viscosity modifier is present in the composition in an amount of about 0.01 wt % to about 5 wt %, wherein the polyamine viscosity modifier reduces the viscosity of the composition such that the composition comprising the polyamine viscosity modifier has a lower viscosity than an equivalent composition without the polyamine viscosity modifier.

US Pat. No. 10,113,075

POLYCYCLIC PHOTOINITIATORS

IGM Malta Limited, (MT)

1. A photopolymerizable composition comprising:(A) at least one ethylenically unsaturated photopolymerizable compound and
(B) at least one photoinitiator compound of formula (I):

wherein
X is O, S, a direct bond or CR16R17;
Y is O or S;
R1, R2, R3, R4, R5, R6, R7 and R8 independently of each other are hydrogen, halogen, C1-C4alkyl, C5-C7cycloalkyl, phenyl, C1-C4alkoxy, C5-C7cycloalkoxy, phenoxy, C1-C4alkylthio, C5-C7cycloalkylthio, phenylthio, di(C1-C4alkyl)amino, di(C5-C7cycloalkyl)amino, N-morpholinyl, N-piperidinyl or a group of formula (II) or (III):

provided that
one of R1, R2, R3 or R4 is a group of formula (II) or (III) and one of R5, R6, R7 or R8 is a group of formula (II) or (III);
R9 and R10 independently of each other are C1-C4alkyl or together with the C atom to which they are attached form a 5-membered, 6-membered or 7-membered carbocyclic ring;
R11 is hydrogen, C1-C4alkyl, C5-C7cycloalkyl, 2-tetrahydropyranyl or Si(C1-C4alkyl)3;
R12 and R13 independently of each other are C1-C4alkyl, C2-C12alkenyl, phenyl-C1-C4alkyl, phenyl-C1-C4alkyl which is substituted by C1-C4alkyl, or R12 and R13 together with the C atom to which they are attached form a 5-membered, 6-membered or 7-membered carbocyclic ring;
R14 and R15 independently of each other are C1-C4alkyl, C5-C7cycloalkyl, or together with the N atom to which they are attached form a 5-membered, 6-membered or 7-membered ring, which may contain additional heteroatoms O, S or N;
R16 and R17 independently of each other are hydrogen, C1-C8alkyl, C5-C7cycloalkyl, phenyl-C1-C4alkyl, phenyl or together with the C atom to which they are attached form a 5-membered, 6-membered or 7-membered ring;
provided that;
(1) compounds wherein R2 is a group of formula (III) and R14 and R15 together with the N atom to which they are attached form a 6-membered ring, which contains an additional heteroatom O, X is a direct bond and Y is O; and
(2) compounds wherein R2 is a group of formula (III) and R14 and R15 together with the N atom to which they are attached form a 6-membered ring, which contains an additional heteroatom O and X and Y are S; and
(3) compounds wherein R7 is a group of formula (III) and R14 and R15 together with the N atom to which they are attached form a 6-membered ring, which contains an additional heteroatom O and X and Y are S; are excluded.

US Pat. No. 10,113,072

ELECTROPHORETIC PARTICLE, METHOD OF MANUFACTURING ELECTROPHORETIC PARTICLE, ELECTROPHORESIS DISPERSION LIQUID, ELECTROPHORESIS SHEET, ELECTROPHORESIS DEVICE, AND ELECTRONIC APPARATUS

E Ink Corporation, Bille...

1. An electrophoretic particle, comprising:a particle including a first functional group on a surface; and
a first compound, a second compound, and a third compound bonded to the particle,
wherein the first compound is a block copolymer that includes a dispersion portion derived from a first monomer including a site that contributes to dispersibility in a dispersion medium, and a bonding portion derived from a second monomer including a second functional group having reactivity with the first functional group, and is connected to the particle by reacting the functional group and the second functional group in the bonding portion,
the second compound has a lower molecular weight than the first compound, includes a non-polar group and the second functional group, and is connected to the particle by the second functional group reacting with the first functional group, and
the third compound has a lower molecular weight than the first compound, includes a charging group and the second functional group, and is connected to the particle by the second functional group reacting with the first functional group.

US Pat. No. 10,113,032

AMINE FUNCTIONAL POLYAMIDES

Genzyme Corporation, Cam...

1. A compound comprising the structure of Formula (II):
wherein:
i) m is 1, 2, or 3;
ii) n is 0, 1, 2, or 3;
iii) o is 1, 2, or 3;
iv) q is an integer from 1 to 400;
v) Qx is NH, (C1-C10)alkyl, (C2-C9)heteroalkyl, (C3-C10)cycloalkyl, (C2-C9)heterocycloalkyl, (C6-C14)aryl, (C2-C9)heteroaryl;
vi) Qv is NH—Rw, NH—CH2—Rw, (C1-C10)alkyl, or (C6-C14)aryl, wherein Rw is absent or a (C1-C10)alkyl, (C2-C9)heteroalkyl, (C6-C14)aryl, or (C2-C9)heteroaryl;
vii) Rx and Ry are each independently a pharmaceutically acceptable end group;
viii) X? is each independently a halo or any pharmaceutically acceptable anion;
ix) Y1 and Y2 are each independently H or (C1-C10)alkyl optionally substituted by one or more substituents selected from the group consisting of (C1-C10)alkyl, (C2-C9)heteroalkyl, (C3-C10)cycloalkyl, (C2-C9)heterocycloalkyl, (C6-C14)aryl, (C2-C9)heteroaryl, (C1-C10)alkylamine, —S—O—(C1-C10)alkyl, —O(O)C—(C1-C10)alkyl, —(C1-C10)alkyl-COOH, (C3-C10)cycloalkyl-COOH, —(O)CH3, —OH, amide, a dihydroxy group, represented by Formula (D),

wherein d is an integer from 0 to 25, or
a polyethylene glycol group, represented by Formula (E)

wherein e is an integer from 1 to 25, and provided that Y1 and Y2 are not both H.

US Pat. No. 10,113,022

PHOTORESIST POLYMERS AND METHODS OF FORMING PATTERNS

Samsung Electronics Co., ...

6. A photoresist polymer synthesized from a repeating unit, the repeating unit comprising:a first leaving group including an ester group; and
a second leaving group capable of being removed with the first leaving group,
wherein the first leaving group and the second leaving group are positioned in one of a staggered conformation and an anti-periplanar configuration,
wherein the second leaving group includes a tosylate group.

US Pat. No. 10,112,975

BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, AND METHODS OF MAKING AND USING

Briston-Myers Squibb Comp...

1. A compound having a structure represented by formula (IIb-03):

US Pat. No. 10,112,974

METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER

Max-Planck-Gesellschaft z...

1. A compound of formula (II)wherein, E represents a covalent bond orwhereinn is an integer selected from 0 to 10;
n1 is an integer selected from 0 to 10;
n2 is an integer selected from 0 to 10;
m is an integer selected from 1 to 18;
p is an integer selected from 0 to 10;
q is an integer selected from 1 to 18;
X, Y, W, and Z represent independently of each other —CH2—, —CH—, —NH— or —N—;
represents a single or double bond;
and diastereomers, entantiomers, hydrates, and salts thereof.

US Pat. No. 10,112,968

INHIBITORS OF PROTEIN METHYLTRANSFERASE DOT1L AND METHODS OF USE THEREOF

Epizyme, Inc., Cambridge...

1. A compound of Formula (IIa) or a pharmaceutically acceptable salt or ester thereof:wherein,A is O or CH2;
each of G and J, independently, is H, halo, C(O)OH, C(O)O—C1-C6 alkyl or ORa, Ra being H, C1-C6 alkyl, C(O)—C1-C6 alkyl, or silyl, wherein C(O)O—C2-C6 alkyl, C1-C6 alkyl or C(O)—C1-C6 alkyl is optionally substituted with one or more substituents selected from the group consisting of halo, cyano hydroxyl, carboxyl, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, and C3-C8 cycloalkyl;
each X independently is N or CRx, in which Rx is H, halo, hydroxyl, carboxyl, cyano, or RS1, RS1 being amino, C1-C6 alkoxyl, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, or 5 to 6-membered heteroaryl, and RS1 being optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, carboxyl, cyano, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, and 5 to 6-membered heteroaryl;
L1 is N(Y), S, SO, or SO2;
L2 is CO or absent when L1 is N(Y) or L2 is absent when L1 is S, SO, or SO2, in which Y is H, Rd, SO2Rd, or CORd when L2 is absent, or Y is H or Rd when L2 is CO, Rd being C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, or 5 to 6-membered heteroaryl, and Rd being optionally substituted with one or more substituents selected from the group consisting of C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, hydroxyl, carboxyl, cyano, C1-C6 alkoxyl, C1-C6 alkylsulfonyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, and 5 to 6-membered heteroaryl and with C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, or 5 to 6-membered heteroaryl further optionally substituted with C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, hydroxyl, carboxyl, C(O)OH, C(O)O—C1-C6 alkyl, OC(O)—C1-C6 alkyl, cyano, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, or 5 to 6-membered heteroaryl;
each of R1, R2, R3, R4, R5, R6, and R7, independently, is H, halo, hydroxyl, carboxyl, cyano, RS2, RS2 being amino, C1-C6 alkoxyl, C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl, and each RS2 being optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, carboxyl, cyano, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, and 5 to 6-membered heteroaryl;
R8 is H, halo or RS3, RS3 being C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl, and RS3 being optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, carboxyl, cyano amino, C1-C6 alkoxyl, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, and C3-C8 cycloalkyl; and
Q is H, NH2, NHRb, NRbRc, Rb, ?O, OH, or ORb, in which each of Rb and Rc independently is C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 7-membered heterocycloalkyl, 5 to 10-membered heteroaryl, or -M1-T1 in which M1 is a bond or C1-C6 alkyl linker optionally substituted with halo, cyano, hydroxyl or C1-C6 alkoxyl and T1 is C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, or 5 to 10-membered heteroaryl, or Rb and Rc, together with the N atom to which they attach, form 4 to 7-membered heterocycloalkyl having 0 or 1 additional heteroatoms to the N atom optionally substituted with C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, hydroxyl, carboxyl, C(O)OH, C(O)O—C1-C6 alkyl, OC(O)—C1-C6 alkyl, cyano, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, or 5 to 6-membered heteroaryl, and each of Rb, Rc, and T1 is optionally substituted with one or more substituents selected from the group consisting of C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, hydroxyl, carboxyl, cyano, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, and 5 to 6-membered heteroaryl;
R9 is
in which:each of Re, Rf, Rg, and Rh, independently is -M2-T2, in which M2 is a bond, SO2, SO, S, CO, CO2, O, O—C1-C4 alkyl linker, C1-C4 alkyl linker, NH, or N(Rt), Rt being C1-C6 alkyl, and T2 is H, halo, or RS4, RS4 being C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 8-membered heterocycloalkyl, or 5 to 10-membered heteroaryl, and each of O—C1-C4 alkyl linker, C1-C4 alkyl linker, Rt, and RS4 being optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, carboxyl, cyano, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, and 5 to 6-membered heteroaryl, Ri is H or C1-C6 alkyl optionally substituted with one or more substituents selected from the group consisting of halo, hydroxyl, carboxyl, cyano, C1-C6 alkoxyl, amino, mono-C1-C6 alkylamino, di-C1-C6 alkylamino, C3-C8 cycloalkyl, C6-C10 aryl, 4 to 6-membered heterocycloalkyl, and 5 to 6-membered heteroaryl;
q is 0, 1, 2, 3, or 4;
m is 0, 1, or 2; and
n is 0, 1, or 2.

US Pat. No. 10,112,967

PROCESS FOR THE PREPARATION OF SOFOSBUVIR

HC-PHARMA AG, Zug (CH)

1. A process for the synthesis of Sofosbuvir of formula (I)
comprising
selectively mono-deacetylating a compound of formula (V)

enzymatically using a resin supported lipase B derived from Candida Antarctica in a polar protic solvent at a temperature from 40° C. to 70° C. to obtain a compound of formula (IV)

converting the compound of formula (IV) to a compound of formula (II)

by reacting the compound of formula (IV) with a compound of formula (III)

wherein F5 indicates that the aromatic ring is pentafluoro substituted, and
converting the compound of formula (II) to Sofosbuvir of formula (I) by deacetylation reaction.

US Pat. No. 10,112,957

THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES

Dana-Farber Cancer Instit...

1. A compound of Formula (I):or a pharmaceutically acceptable salt thereof, wherein:each instance of RA1 is independently halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted carbocyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, —ORa, —N(Ra)2, —SRa, —CN, —SCN, —C(?NRa)Ra, —C(?NRa)ORa, —C(?NRa)N(Ra)2, —C(?O)Ra, —C(?O)ORa, —C(?O)N(Ra)2, —NO2, —NRaC(?O)Ra, —NRaC(?O)ORa, —NRaC(?O)N(Ra)2, —OC(?O)Ra, —OC(?O)ORa, or —OC(?O)N(Ra)2;
each instance of Ra is independently hydrogen, substituted or unsubstituted acyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted carbocyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, a nitrogen protecting group when attached to a nitrogen atom, an oxygen protecting group when attached to an oxygen atom, or a sulfur protecting group when attached to a sulfur atom, or two instances of Ra are joined to form a substituted or unsubstituted, heterocyclic ring, or substituted or unsubstituted, heteroaryl ring;
k is 0, 1, 2, 3, 4, or 5;
LA is —C(?O)—NRA2— or —NRA2—C(?O)—, wherein RA2 is hydrogen, substituted or unsubstituted C1-6 alkyl, or a nitrogen protecting group;
RA3 is hydrogen, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted carbocyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, —ORa, —N(Ra)2, —SRa, —CN, —SCN, —C(?NRa)Ra, —C(?NRa)ORa, —C(?NRa)N(Ra)2, —C(?O)Ra, —C(?O)ORa, —C(?O)N(Ra)2, —NO2, —NRaC(?O)Ra, —NRaC(?O)ORa, —NRaC(?O)N(Ra)2, —OC(?O)Ra, —OC(?O)ORa, or —OC(?O)N(Ra)2;
RA4 is hydrogen, substituted or unsubstituted C1-6 alkyl, or a nitrogen protecting group;
each instance of RA5 is independently halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted carbocyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, —ORa, —N(Ra)2, —SRa, —CN, —SCN, —C(?NRa)Ra, —C(?NRa)ORa, —C(?NRa)N(Ra)2, —C(?O)Ra, —C(?O)ORa, —C(?O)N(Ra)2, —NO2, —NRaC(?O)Ra, —NRaC(?O)ORa, —NRaC(?O)N(Ra)2, —OC(?O)Ra, —OC(?O)ORa, or —OC(?O)N(Ra)2;
m is 0, 1, or 2;
RA6 is hydrogen, substituted or unsubstituted C1-6 alkyl, or a nitrogen protecting group; and
RA7 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted carbocyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroaryl, —C(?O)Ra, —C(?O)ORa, —C(?O)N(Ra)2, or a nitrogen protecting group;
wherein:
each substituent at a carbon atom is independently halogen, —CN, —NO2, —N3, —SO2H, —SO3H, —OH, —ORaa, —ON(Rbb)2, —N(Rbb)2, —N(Rbb)3+X?, —N(ORcc)Rbb, —SH, —SRaa, —SSRcc, —C(?O)Raa, —CO2H, —CHO, —C(ORcc)2, —CO2Raa, —OC(?O)Raa, —OCO2Raa, —C(?O)N(Rbb)2, —OC(?O)N(Rbb)2, —NRbbC(?O)Raa, —NRbbCO2Raa, —NRbbC(?O)N(Rbb)2, —C(?NRbb)Raa, —C(?NRbb)ORaa, —OC(?NRbb)Raa, —OC(?NRbb)ORaa, —C(?NRbb)N(Rbb)2, —OC(?NRbb)N(Rbb)2, —NRbbC(?NRbb)N(Rbb)2, —C(?O)NRbbSO2Raa, —NRbbSO2Raa, —SO2N(Rbb)2, —SO2Raa, —SO2ORaa, —OSO2Raa, —S(?O)Raa, —OS(?O)Raa, —Si(Raa)3, —OSi(Raa)3, —C(?S)N(Rbb)2, —C(?O)SRaa, —C(?S)SRaa, —SC(?S)SRaa, —SC(?O)SRaa, —OC(?O)SRaa, —SC(?O)ORaa, —SC(?O)Raa, —P(?O)(Raa)2, —P(?O)(ORcc)2, —OP(?O)(Raa)2, —OP(?O)(ORcc)2, —P(?O)(N(Rbb)2)2, —OP(?O)(N(Rbb)2)2, —NRbbP(?O)(Raa)2, —NRbbP(?O)(ORcc)2, —NRbbP(?O)(N(Rbb)2)2, —P(Rcc)2, —P(ORcc)2, —P(Rcc)3+X?, —P(ORcc)3+X?, —P(Rcc)4, —P(ORcc)4, —OP(Rcc)2, —OP(Rcc)3+X?, —OP(ORcc)2, —OP(ORcc)3+X?, —OP(Rcc)4, —OP(ORcc)4, —B(Raa)2, —BRaa(ORcc), C1-10 alkyl, C1-10 perhaloalkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-14 aryl, or heteroaryl, wherein each one of the alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rdd groups;
or two geminal hydrogens on a carbon atom are replaced with the group ?O, ?S, ?NN(Rbb)2, ?NNRbbC(?O)Raa, ?NNRbbC(?O)ORaa, ?NNRbbS(?O)2Raa, ?NRbb, or ?NORcc;
each substituent on a nitrogen atom is independently hydrogen, —OH, —ORaa, —N(Rcc)2, —CN, —C(?O)Raa, —C(?O)N(Rcc)2, —CO2Raa, —SO2Raa, —C(?NRbb)Raa, —C(?NRcc)ORaa, —C(?NRcc)N(Rcc)2, —SO2N(Rcc)2, —SO2Rcc, —SO2Rcc, —SO2ORcc, —SORaa, —C(?S)N(Rcc)2, —C(?O)SRcc, —C(?S)SRcc, —P(?O)(ORcc)2, —P(?O)(Raa)2, —P(?O)(N(Rcc)2)2), C1-10 alkyl, C1-10 perhaloalkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-14 aryl, or heteroaryl, wherein each one of the alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rdd groups;
each instance of the acyl is independently —C(?O)Raa, —CHO, —CO2Raa, —C(?O)N(Rbb)2, —C(?NRbb)Raa, —C(?NRbb)ORaa, —C(?NRbb)N(Rbb)2, —C(?O)NRbbSO2Raa, —C(?S)N(Rbb)2, —C(?O)SRaa, or —C(?S)SRaa;
each instance of Raa is independently C1-10 alkyl, C1-10 perhaloalkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-14 aryl, or heteroaryl, or two Raa groups are joined to form heterocyclyl or heteroaryl, wherein each alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rdd groups;
each instance of Rbb is independently hydrogen, —OH, —ORaa, —N(Rcc)2, —CN, —C(?O)Raa, —C(?O)N(Rcc)2, —CO2Raa, —SO2Raa, —C(?NRcc)ORaa, —C(?NRcc)N(Rcc)2, —SO2N(Rcc)2, —SO2Rcc, —SO2Rcc, —SORaa, —C(?S)N(Rcc)2, —C(?O)SRcc, —C(?S)SRcc, —P(?O)(Raa)2, —P(?O)(ORcc)2, —P(?O)(N(Rcc)2)2), C1-10 alkyl, C1-10 perhaloalkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-14 aryl, or heteroaryl, or two Rbb groups are joined to form heterocyclyl or heteroaryl, wherein each alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rdd groups;
each instance of Rcc is independently hydrogen, C1-10 alkyl, C1-10 perhaloalkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-14 aryl, or heteroaryl, or two Rcc groups are joined to form heterocyclyl or heteroaryl, wherein each one of the alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rdd groups;
each instance of Rdd is independently halogen, —CN, —NO2, —N3, —SO2H, —SO3H, —OH, —ORee, —ON(Rff)2, —N(Rff)2, —N(Rff)3+X?, —N(ORee)Rff, —SH, —SRee, —SSRee, —C(?O)Ree, —CO2H, —CO2Ree, —OC(?O)Ree, —OCO2Ree, —C(?O)N(Rff)2, —OC(?O)N(Rff)2, —NRffC(?O)Ree, —NRffCO2Ree, —NRffC(?O)N(Rff)2, —C(?NRff)ORee, —C(?NRff)Ree, —OC(?NRff)ORee, —C(?NRff)N(Rff)2, —OC(?NRff)N(Rff)2, —NRffC(?NRff)N(Rff)2, —NRffSO2Ree, —SO2N(Rff)2, —SO2Ree, —SO2ORee, —OSO2Ree, —S(?O)Ree, —Si(Ree)3, —OSi(Ree)3, —C(?S)N(Rff)2, —C(?O)SRee, —C(?S)SRee, —SC(?S)SRee, —P(?O)(ORee)2, —P(?O)(Ree)2, —OP(?O)(Ree)2, —OP(?O)(ORee)2, C1-6 alkyl, C1-6 perhaloalkyl, C2-6 alkenyl, C2-6 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-10 aryl, or heteroaryl, wherein each one of the alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rgg groups, or two geminal Rdd substituents are joined to form ?O or ?S;
each instance of Ree is independently C1-6 alkyl, C1-6 perhaloalkyl, C2-6 alkenyl, C2-6 alkynyl, C3-10 carbocyclyl, C6-10 aryl, heterocyclyl, or heteroaryl, wherein each one of the alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rgg groups;
each instance of Rff is independently hydrogen, C1-6 alkyl, C1-6 perhaloalkyl, C2-6 alkenyl, C2-6 alkynyl, C3-10 carbocyclyl, heterocyclyl, C6-10 aryl, or heteroaryl, or two Rff groups are joined to form heterocyclyl or heteroaryl, wherein each one of the alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl is independently substituted with 0, 1, 2, 3, 4, or 5 Rgg groups;
each instance of Rgg is independently halogen, —CN, —NO2, —N3, —SO2H, —SO3H, —OH, —OC1-6 alkyl, —ON(C1-6 alkyl)2, —N(C1-6 alkyl)2, —N(C1-6 alkyl)3+X?, —NH(C1-6 alkyl)2+X?, —NH2(C1-6 alkyl)+X?, —NH3+X?, —N(OC1-6 alkyl)(C1-6 alkyl), —N(OH)(C1-6 alkyl), —NH(OH), —SH, —SC1-6 alkyl, —SS(C1-6 alkyl), —C(?O)(C1-6 alkyl), —CO2H, —CO2(C1-6 alkyl), —OC(?O)(C1-6 alkyl), —OCO2(C1-6 alkyl), —C(?O)NH2, —C(?O)N(C1-6 alkyl)2, —OC(?O)NH(C1-6 alkyl), —NHC(?O)(C1-6 alkyl), —N(C1-6 alkyl)C(?O)(C1-6 alkyl), —NHCO2(C1-6 alkyl), —NHC(?O)N(C1-6 alkyl)2, —NHC(?O)NH(C1-6 alkyl), —NHC(?O)NH2, —C(?NH)O(C1-6 alkyl), —OC(?NH)(C1-6 alkyl), —OC(?NH)OC1-6 alkyl, —C(?NH)N(C1-6 alkyl)2, —C(?NH)NH(C1-6 alkyl), —C(?NH)NH2, —OC(?NH)N(C1-6 alkyl)2, —OC(NH)NH(C1-6 alkyl), —OC(NH)NH2, -NHC(NH)N(C1-6 alkyl)2, —NHC(?NH)NH2, —NHSO2(C1-6 alkyl), —SO2N(C1-6 alkyl)2, —SO2NH(C1-6 alkyl), —SO2NH2, —SO2C1-6 alkyl, —SO2OC1-6 alkyl, —OSO2C1-6 alkyl, —SOC1-6 alkyl, —Si(C1-6 alkyl)3, —OSi(C1-6 alkyl)3—C(?S)N(C1-6 alkyl)2, C(?S)NH(C1-6 alkyl), C(?S)NH2, —C(?O)S(C1-6 alkyl), —C(?S)SC1-6 alkyl, —SC(?S)SC1-6 alkyl, —P(?O)(OC1-6 alkyl)2, —P(?O)(C1-6 alkyl)2, —OP(?O)(C1-6 alkyl)2, —OP(?O)(OC1-6 alkyl)2, C1-6 alkyl, C1-6 perhaloalkyl, C2-6 alkenyl, C2-6 alkynyl, C3-10 carbocyclyl, C6-10 aryl, heterocyclyl, or heteroaryl; or two geminal Rgg substituents are joined to form ?O or ?S;
X? is a counterion;
each instance of the heteroaryl and heteroaryl ring independently is 5- to 10-membered, and monocyclic or bicyclic, and has ring carbon atoms and 1 to 4 ring heteroatoms;
each instance of the heterocyclyl and heterocyclic ring independently is 3- to 10-membered; saturated or partially unsaturated; non-aromatic; and monocyclic, fused bicyclic, bridged bicyclic, or spiro bicyclic; and has ring carbon atoms and 1 to 4 ring heteroatoms;
each instance of the ring heteroatoms is independently nitrogen, oxygen, or sulfur; and
each instance of the nitrogen protecting group is independently formamide, acetamide, chloroacetamide, trichloroacetamide, trifluoroacetamide, phenylacetamide, 3-phenylpropanamide, picolinamide, 3-pyridylcarboxamide, N-benzoylphenylalanyl, benzamide, p-phenylbenzamide, o-nitophenylacetamide, o-nitrophenoxyacetamide, acetoacetamide, (N?-dithiobenzyloxyacylamino)acetamide, 3-(p -hydroxyphenyl)propanamide, 3-(o-nitrophenyl)propanamide, 2-methyl-2-(o -nitrophenoxy)propanamide, 2-methyl-2-(o-phenylazophenoxy)propanamide, 4-chlorobutanamide, 3-methyl-3-nitrobutanamide, o-nitrocinnamide, N-acetylmethionine, o -nitrobenzamide, o-(benzoyloxymethyl)benzamide, methyl carbamate, ethylcarbamate, 9-fluorenylmethyl carbamate (Fmoc), 9-(2-sulfo)fluorenylmethyl carbamate, 9-(2,7-dibromo)fluoroenylmethyl carbamate, 2,7-di-t-butyl[9-(10,10-dioxo-10,10,10,10-tetrahydrothioxanthyl)]methyl carbamate (DBD-Tmoc), 4-methoxyphenacyl carbamate (Phenoc), 2,2,2-trichloroethyl carbamate (Troc), 2-trimethylsilylethyl carbamate (Teoc), 2-phenylethyl carbamate (hZ), 1-(1-adamantyl)-1-methylethyl carbamate (Adpoc), 1,1-dimethyl-2-haloethyl carbamate, 1,1-dimethyl-2,2-dibromoethyl carbamate (DB-t-BOC), 1,1-dimethyl-2,2,2-trichloroethyl carbamate (TCBOC), 1-methyl-1-(4-biphenylyl)ethyl carbamate (Bpoc), 1-(3,5-di-t-butylphenyl)-1-methylethyl carbamate (t-Bumeoc), 2-(2?- or 4?-pyridyl)ethyl carbamate (Pyoc), 2-(N,N-dicyclohexylcarboxamido)ethyl carbamate, t -butyl carbamate (BOC or Boc), 1-adamantyl carbamate (Adoc), vinyl carbamate (Voc), allyl carbamate (Alloc), 1-isopropylallyl carbamate (Ipaoc), cinnamyl carbamate (Coc), 4-nitrocinnamyl carbamate (Noc), 8-quinolyl carbamate, N-hydroxypiperidinyl carbamate, alkyldithio carbamate, benzyl carbamate (Cbz), p-methoxybenzyl carbamate (Moz), p-nitobenzyl carbamate, p-bromobenzyl carbamate, p-chlorobenzyl carbamate, 2,4-dichlorobenzyl carbamate, 4-methylsulfinylbenzyl carbamate (Msz), 9-anthrylmethyl carbamate, diphenylmethyl carbamate, 2-methylthioethyl carbamate, 2-methylsulfonylethyl carbamate, 2-(p-toluenesulfonyl)ethyl carbamate, [2-(1,3-dithianyl)]methyl carbamate (Dmoc), 4-methylthiophenyl carbamate (Mtpc), 2,4-dimethylthiophenyl carbamate (Bmpc), 2-phosphonioethyl carbamate (Peoc), 2-triphenylphosphonioisopropyl carbamate (Ppoc), 1,1-dimethyl-2-cyanoethyl carbamate, m-chloro-p-acyloxybenzyl carbamate, p -(dihydroxyboryl)benzyl carbamate, 5-benzisoxazolylmethyl carbamate, 2-(trifluoromethyl)-6-chromonylmethyl carbamate (Tcroc), m-nitrophenyl carbamate, 3,5-dimethoxybenzyl carbamate, o-nitrobenzyl carbamate, 3,4-dimethoxy-6-nitrobenzyl carbamate, phenyl(o-nitrophenyl)methyl carbamate, t-amyl carbamate, S-benzyl thiocarbamate, p-cyanobenzyl carbamate, cyclobutyl carbamate, cyclohexyl carbamate, cyclopentyl carbamate, cyclopropylmethyl carbamate, p-decyloxybenzyl carbamate, 2,2-dimethoxyacylvinyl carbamate, o-(N,N-dimethylcarboxamido)benzyl carbamate, 1,1-dimethyl-3-(N,N-dimethylcarboxamido)propyl carbamate, 1,1-dimethylpropynyl carbamate, di(2-pyridyl)methyl carbamate, 2-furanylmethyl carbamate, 2-iodoethyl carbamate, isoborynl carbamate, isobutyl carbamate, isonicotinyl carbamate, p-(p?-methoxyphenylazo)benzyl carbamate, 1-methylcyclobutyl carbamate, 1-methylcyclohexyl carbamate, 1-methyl-1-cyclopropylmethyl carbamate, 1-methyl-1-(3,5-dimethoxyphenyl)ethyl carbamate, 1-methyl-1-(p-phenylazophenyl)ethyl carbamate, 1-methyl-1-phenylethyl carbamate, 1-methyl-1-(4-pyridyl)ethyl carbamate, phenyl carbamate, p-(phenylazo)benzyl carbamate, 2,4,6-tri-t-butylphenyl carbamate, 4-(trimethylammonium)benzyl carbamate, 2,4,6-trimethylbenzyl carbamate, p -toluenesulfonamide (Ts), benzenesulfonamide, 2,3,6,-trimethyl-4-methoxybenzenesulfonamide (Mtr), 2,4,6-trimethoxybenzenesulfonamide (Mtb), 2,6-dimethyl-4-methoxybenzenesulfonamide (Pme), 2,3,5,6-tetramethyl-4-methoxybenzenesulfonamide (Mte), 4-methoxybenzenesulfonamide (Mbs), 2,4,6-trimethylbenzenesulfonamide (Mts), 2,6-dimethoxy-4-methylbenzenesulfonamide (iMds), 2,2,5,7,8-pentamethylchroman-6-sulfonamide (Pmc), methanesulfonamide (Ms), ?-trimethylsilylethanesulfonamide (SES), 9-anthracenesulfonamide, 4-(4?,8?-dimethoxynaphthylmethyl)benzenesulfonamide (DNMBS), benzylsulfonamide, trifluoromethylsulfonamide, phenacylsulfonamide, phenothiazinyl-(10)-acyl, N?-p -toluenesulfonylaminoacyl, N?-phenylaminothioacyl, N-benzoylphenylalanyl, N -acetylmethionine, 4,5-diphenyl-3-oxazolin-2-one, N-phthalimide, N-dithiasuccinimide (Dts), N-2,3-diphenylmaleimide, N-2,5-dimethylpyrrole, N-1,1,4,4-tetramethyldisilylazacyclopentane adduct (STABASE), 5-substituted 1,3-dimethyl-1,3,5-triazacyclohexan-2-one, 5-substituted 1,3-dibenzyl-1,3,5-triazacyclohexan-2-one, 1-substituted 3,5-dinitro-4-pyridone, N-methylamine, N-allylamine, N-[2-(trimethylsilyl)ethoxy]methylamine (SEM), N-3-acetoxypropylamine, N-(1-isopropyl-4-nitro-2-oxo-3-pyroolin-3-yl)amine, quaternary ammonium salt, N-benzylamine, N-di(4-methoxyphenyl)methylamine, N-5-dibenzosuberylamine, N-triphenylmethylamine (Tr), N -[(4-methoxyphenyl)diphenylmethyl]amine (MMTr), N-9-phenylfluorenylamine (PhF), N -2,7-dichloro-9-fluorenylmethyleneamine, N-ferrocenylmethylamino (Fcm), N-2-picolylamino N?-oxide, N-1,1-dimethylthiomethyleneamine, N-benzylideneamine, N-p -methoxybenzylideneamine, N-diphenylmethyleneamine, N-[(2-pyridyl)mesityl]methyleneamine, N-(N?,N?-dimethylaminomethylene)amine, N,N?-isopropylidenediamine, N-p-nitrobenzylideneamine, N-salicylideneamine, N-5-chlorosalicylideneamine, N-(5-chloro-2-hydroxyphenyl)phenylmethyleneamine, N -cyclohexylideneamine, N-(5,5-dimethyl-3-oxo-1-cyclohexenyl)amine, N-borane, N -diphenylborinic acid, N-[phenyl(pentaacylchromium- or tungsten)acyl]amine, N-copper chelate, N-zinc chelate, N-nitroamine, N-nitrosoamine, amine N-oxide, diphenylphosphinamide (Dpp), dimethylthiophosphinamide (Mpt), diphenylthiophosphinamide (Ppt), dialkyl phosphoramidate, dibenzyl phosphoramidate, diphenyl phosphoramidate, benzenesulfenamide, o-nitrobenzenesulfenamide (Nps), 2,4-dinitrobenzenesulfenamide, pentachlorobenzenesulfenamide, 2-nitro-4-methoxybenzenesulfenamide, triphenylmethylsulfenamide, or 3-nitropyridinesulfenamide (Npys).

US Pat. No. 10,112,908

METHODS FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVES

DAICHI SANKYO COMPANY, LI...

1. A method of producing a compound of formula (4):
comprising allowing a compound of formula (1):
to react with hydrogen gas, in an inert solvent, in the presence of a chiral ligand of formula (2) or (3):orand a ruthenium catalyst, or in the presence of an asymmetric transition metal complex catalyst previously generated from the chiral ligand and the ruthenium catalyst,wherein R is a protective group for the carboxy group or a hydrogen atom,
R1 and R2 are each independently a hydrogen atom or a protective group for the amino group,
Ar is a phenyl group, a 3,5-dimethylphenyl group or a 4-methylphenyl group, and
Ar? is a phenyl group, a 3,5-dimethylphenyl group or a 3,5-di-tert-butyl-4-methoxyphenyl group.

US Pat. No. 10,112,905

MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS

LOHOCLA RESEARCH CORPORAT...

1. A method of treating or preventing alcohol addiction relapse in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a compound or a pharmaceutically acceptable salt thereof; wherein the subject is abstinent from alcohol; and wherein the compound has the structure:
to treat or prevent the alcohol addiction relapse.

US Pat. No. 10,112,904

PROCESS FOR PREPARING SYNTHETIC INTERMEDIATES FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES

DEZIMA PHARMA B.V., Naar...

1. A process for preparing the racemic compound of formula I or a salt thereof:
comprising the steps of:(a) simultaneously reacting 4-aminobenzotrifluoride according to formula IIwith an aldehyde according to formula IIIand with a compound according to formula IV
in the presence of a solvent and optionally one or more catalysts to form the compound of formula V

whereinR1 is H or C1-C3 alkyl;R2 is H, C1-C3 alkyl or(b) hydrolyzing the compound of formula V to form the compound of formula (I); wherein prior to step (b) the compound of formula V is separated from the reaction mixture of step (a).

US Pat. No. 10,112,900

MODIFIED AMINO ACIDS

SUTRO BIOPHARMA, INC., S...

1. A compound according to formula I:
or a salt thereof, wherein:
D is Ar—W3— or —W1—Y1—C(O)—Y2—W2—;
Ar is

each of W1, W2, and W3 is independently a single bond or lower alkylene;
X1 is —O— or —S—;
Y1 is a single bond, —NH—, or —O—;
Y2 is an N-linked or C-linked divalent pyrrolidine radical; and
one of Z1, Z2, and Z3 is —N— and the others of Z1, Z2, and Z3 are independently —CH—.

US Pat. No. 10,112,889

CONTINUOUS PROCESS FOR PRODUCING A SURFACTANT IN A TUBE REACTOR

CLARIANT INTERNATIONAL LT...

1. A continuous process for preparing a surfactant, wherein the surfactant comprises a compound of the formula (1), in which R2 is a fatty acid alkyl radical and R1 is a straight-chain or branched C1 to C12 hydrocarbyl radical and x is in the range from 1 to 15
wherein the continuous process comprises at least the step of reacting at least one fatty acid alkyl ester or fatty acid triglyceride with at least one N-n-alkylated polyhydroxyamine in the presence of an alkali metal catalyst or of a catalyst selected from the group consisting of hydroxides or alkoxides of transition groups 2 and 4 of the Periodic Table, at a temperature in the range from 40 to 300° C., wherein the continuous process comprises the following steps:
1. mixing an aqueous raw material solution comprising at least one N-n-alkylated polyhydroxyamine with the catalyst to form an aqueous solution;
2. drying the aqueous solution, wherein the water content after drying being in the range of 0-5 wt % to form a dried mixture;
3. heating the dried mixture to a temperature in the range from 60 to 180° C. to form a melt, and mixing the melt with fatty acid alkyl esters or triglycerides to form a reaction mixture;
4. optionally, intermediately storing and mixing the reaction mixture in a continuously operated stirred tank;
5. carrying out reaction in a tube reactor; and optionally
6. removing any coproducts.

US Pat. No. 10,112,869

HIGH-ALUMINA REFRACTORY ALUMINOSILICATE POZZOLAN IN WELL CEMENTING

Halliburton Enegry Servic...

1. A method of cementing comprising:introducing a cement composition into a subterranean formation, wherein the cement composition comprises: a component selected from the group consisting of cement kiln dust, and any combination thereof; a high-alumina refractory aluminosilicate pozzolan; and water, wherein the high-alumina refractory aluminosilicate pozzolan comprises Mullite in an amount of about 30 weight % or greater, wherein the high-alumina refractory aluminosilicate pozzolan comprises Corundum in an amount of about 10 weight % or greater, and wherein high-alumina refractory aluminosilicate pozzolan is substantially devoid of amorphous material; and allowing the cement composition to set.

US Pat. No. 10,112,858

MEDIA BED FOR WASTE STREAMS AND METHODS AND SYSTEMS EMPLOYING THE SAME

INTEGRATED AGRICULTURE SY...

1. A method of treating waste comprising:(a) providing an apparatus comprising a media bed comprising a substantially water tight container comprising a biomass, wherein (i) the biomass comprises water and viable worms that are submerged in the water, and (ii) the worms are at a density of about 1000 worms/m3 to about 100,000 worms/m3;
(b) introducing oxygen into the water of the biomass by an aeration means configured to introduce air or oxygen into the water, wherein a dissolved oxygen content of the water is maintained at a level of at least 4 ppm;
(c) maintaining the viable worms in an aquatic environment, wherein the worms are completely and constantly submerged in the water;
(d) contacting the biomass of the apparatus with oxidizable waste, thereby forming a mixture; and
(e) removing a portion of the mixture from the apparatus wherein the portion of the mixture that is removed comprises treated waste.

US Pat. No. 10,112,841

METHOD FOR CATALYTIC AMMONIA SYNTHESIS UNDER CONCENTRATED SOLAR ENERGY AND CATALYSTS

CENTRAL CHINA NORMAL UNIV...

10. The method of claim 9, further comprising:impregnating the obtained active ingredient into an promoter solution so as to obtain the catalyst after drying in an oxygen-free atmosphere or in vacuum.

US Pat. No. 10,112,824

SEMICONDUCTOR DEVICE

ROHM CO., LTD., Kyoto (J...

1. A semiconductor device comprising:a substrate made of a semiconductor material and having an obverse surface formed with a recess;
a wiring layer formed on the substrate;
at least one functional element disposed in the recess and electrically connected to the wiring layer; and
an additional element controlling an orientation detection process that involves the at least one functional element, the additional element overlapping with at least a part of the at least one functional element as viewed in a direction normal to the obverse surface of the substrate,
wherein the recess comprises a first hollow that houses the at least one functional element, the first hollow having a first bottom surface and at least one first inclined side surface, and the first inclined side surface being connected to the first bottom surface,
the wiring layer including a portion on the first inclined side surface, the portion of the wiring layer extending from an upper edge of the first inclined side surface on the first inclined side surface, the upper edge of the first inclined side surface extending in a first direction perpendicular to the direction normal to the obverse surface of the substrate,
as viewed in the direction normal to the obverse surface of the substrate, the portion of the wiring layer comprises a first extension extending in the first direction and a second extension extending in a second direction that is perpendicular to the first direction and the direction normal to the obverse surface of the substrate,
the recess comprises a second hollow that has a second bottom surface and at least one second inclined side surface, the second bottom surface being connected to the first inclined side surface, the second inclined side surface being connected to the second bottom surface and the obverse surface, and
an angle of the first inclined side surface relative to the first bottom surface is less than 90 degrees.

US Pat. No. 10,112,821

LIQUID DISPENSING APPLIANCE PROVIDED WITH AN ANTI-DRIP VALVE SYSTEM

Anheuser-Busch InBev S.A....

1. A pressure driven dispensing assembly comprising a container containing a beverage to be dispensed, a dispensing tube bringing in fluid communication with ambient the volume inside the container containing the beverage, and a source of pressurized gas in fluid communication with the interior of the container for pressurizing the interior of the container and driving the dispensing of the beverage out of the container through the dispensing tube, said dispensing tube having a flexible, resilient portion ending in an outlet of inner diameter, D, is at least 3 mm, and being engaged in a pinch valve system comprising a squeezing member suitable for squeezing and obturating a single section of the flexible portion located at a distance, h, from the outlet comprised between 1 and 12 mm, wherein the ratio, h/D, of the distance, h, to the outlet inner diameter, D, is not more than 1.5, so as to reduce the dripping of the beverage out of the dispensing tube when obturating the section.

US Pat. No. 10,112,819

EXTRACTOR TUBE

1. The extractor tube assembly for a beverage container, comprising:an extraction tube; and
a first extractor tube element and a second extractor tube element;
the first extractor tube element having a first contact surface extending radially outwards from an exterior surface of the extraction tube, the first contact surface being positioned and arranged so as to abut a second surface of the second extractor tube element, wherein the first contact surface has at least one protrusion, the at least one protrusion tapering into a contact point for reducing a contact area between the first extractor tube element and the second extractor tube element and for creating space between the abutting first and second extractor tube elements to facilitate cleaning.

US Pat. No. 10,112,816

METHOD FOR FILLING A CONTAINER WITH A FILL PRODUCT USING A PROPORTIONAL VALVE

KRONES AG, Neutraubling ...

1. A method for filling a container with a fill product, comprising:determining a volume of fluid flowing through a proportional valve per unit time for each of a plurality of open positions of the proportional valve for a specified opening curve (H(t)) of the proportional valve to generate a curve of volume of the fluid flowing through the proportional valve as a function of time; and
controlling the filling of the container based on the curve.

US Pat. No. 10,112,812

GANTRY BINARY SYNCHRONIZATION BLOCK-TYPE BRAKE

SHIJIAZHUANG WULONG BRAKE...

1. A gantry binary synchronization block brake for frictionally braking a braking wheel, comprising:a gantry bracket;
a dual brake releaser secured to the gantry bracket; and
two mutually independent braking units,
wherein the gantry bracket further comprises two side frames, a top beam fixedly disposed on the upper ends of the two side frames, and a base connected to lower ends of the two side frames,
each of the braking units comprises:
a braking arm arranged on a side of the gantry bracket with lower end of the braking arm hinged to the gantry bracket;
a braking shoe connected to the braking arm for frictionally braking the braking wheel;
a braking spring provided on the braking arm for pushing the braking arm so as to brake the braking wheel; and
an adjusting screw for adjusting a working gap between the braking shoe and the braking wheel;
wherein the adjusting screw extends in and is fixed onto the braking arm, the adjusting screw is locked to the braking arm by a locking nut, an inner end of the adjusting screw remains axially opposite to an adjacent push rod on the dual brake releaser, the adjusting screw is axially movable relative to the push rod; and
the gap adjustment mechanism adjusts a braking working gap between the braking shoe and the braking wheel by adjusting an extension length of the adjusting screw from inside of the braking arm.

US Pat. No. 10,112,798

SPOOL ASSEMBLY AND METHOD OF USE THEREOF

PLOMBCO INC., Salaberry-...

1. A spool comprising:a rotation axis;
a proximal side orthogonal to the rotation axis;
a distal side orthogonal to the rotation axis with an intervening distance with the proximal side to receive a strip of material therebetween;
a central opening coaxial with the rotation axis and extending through the spool between the proximal side and the distal side;
an axial slot axially extending through the spool and radially extending from the central opening for slidably receiving therein a locking member when the spool is engaged by a support shaft;
a locking member receiver radially located and recessed in the distal side of the spool for securing therein the locking member radially extending from the support shaft; and
a recessed portion adjacent to the central opening in the distal side of the spool and communicating with the central opening between the axial slot and the locking member receiver, the recessed portion restricting an angular pivotal movement of the locking member when the locking member has been axially engaged through the axial slot and extending through the spool toward the distal side of the spool for securing the locking member in the locking member receiver.

US Pat. No. 10,112,796

METHOD AND APPARATUS FOR MANUFACTURING AEROGEL SHEET

LG CHEM, LTD., Seoul (KR...

1. A method for manufacturing an aerogel sheet, the method comprising:a step (a) of preparing silica sol;
a step (b) of preparing a gelling catalyst;
a step (c) of injecting the silica sol, which is prepared in the step (a), to a surface of a blanket to impregnate the silica sol;
a step (d) of injecting the gelling catalyst, which is prepared in the step (b), to the surface of the blanket, into which the silica sol is impregnated, to gelate the silica sol; and
a step (e) of cutting the blanket, in which the silica sol is gelated, to obtain a sheet in which the silica sol is gelated,
wherein the step (c) and the step (d) are performed within a conveyor belt that transfers the blanket from one side to the other side thereof,
wherein the conveyor belt comprises a scraper comprising a first scraper adjusting a thickness of the silica sol injected to the surface of the blanket and a second scraper adjusting a thickness of the gelling catalyst injected to the surface of the blanket,
wherein the first scraper and the second scraper may be installed to be adjustable in height on a top surface of the conveyor belt,
wherein, in the step (d), the gelling catalyst is injected to the surface of the blanket at a rate of 0.035 L/min to 0.012 L/min to leave the gelling catalyst for 8 minutes to 12 minutes and thereby to gelate the silica sol, and
wherein, in the step (d), the gelation of the silica sol is uniformly adjusted by varying the injection rate of the gelling catalyst according to density of the silica sol impregnated in the blanket.

US Pat. No. 10,112,795

DEVICE FOR CLOSING THE TAIL END OF A ROLL OF WEB MATERIAL, AND METHOD

MTORRES TISSUE S.R.L., (...

1. A device for closing a tail end of a roll of web material comprising:a feeding path of the roll to be closed;
a closing station along the feeding path of the roll for closing the tail end of the roll;
in the closing station of the tail end of the roll, two rollers forming a cradle for receiving the roll and a closing member for closing the tail end;
an assembly rotating around a rotating axis transverse with respect to the feeding path, and comprising groups of arms arranged with respect to one another angularly displaced around said rotation axis, each arm comprising a front part configured to eject the roll from the cradle and a back part, configured to hold subsequent rolls along the feeding path, thus preventing them from entering in the closing station until the roll has been ejected from said cradle, a one-step rotation of said rotating assembly causing ejection of the closed roll from the cradle and allowing one subsequent roll to be closed to enter said cradle.

US Pat. No. 10,112,790

FEEDING APPARATUS

Funai Electric Co., Ltd.,...

1. A feeding apparatus comprising:a mounting portion that holds a medium;
a first feeding roller that feeds the medium toward a feeding direction;
a first stopper that prevents the medium from moving toward the feeding direction,
wherein the first stopper pivots with respect to a pivotal axis, and the pivotal axis of the first stopper is substantially identical with a rotational axis of the first feeding roller;
a supporting part that swings the first feeding roller between:
a first position in which the first feeding roller feeds the medium while both the first feeding roller and the first stopper contact the medium, and
a second position in which the first feeding roller does not contact the medium while the first stopper contacts the medium to prevent the medium from moving toward the feeding direction; and
a regulating part disposed on a downstream side in feeding direction with respect to a pivotal center of the supporting part,
wherein the regulating part regulates movement of the first stopper by contacting a portion of the first stopper that does not contact the medium in the first position.

US Pat. No. 10,112,785

TRANSFER MECHANISM FOR USE WITH A FOOD PROCESSING SYSTEM

Lyco Manufacturing Inc., ...

1. A transfer mechanism for transferring food product from a compartment of a food processing system, the transfer mechanism comprising:a conduit including a first end portion configured to be in communication with the compartment and a second end portion, wherein food product in the compartment enters the first end portion;
a liquid discharge positioned substantially within the conduit between the first end portion and the second end portion; and
a pressurized fluid source in communication with the liquid discharge, the pressurized fluid source operable to propel a liquid through the liquid discharge into the conduit and toward the second end of the conduit without propelling food product through the pressurized fluid source, wherein the liquid propelled toward the second end of the conduit moves the food product from the first end portion of the conduit toward the second end portion.

US Pat. No. 10,112,781

CONTAINER AUTOROTATION DEVICE AND CONTAINER AUTOROTATION METHOD

LEADWAY (HK) LIMITED, Ho...

1. A container autorotation device, comprising a conveying rack, at least one container base and a driving component, wherein the conveying rack is used for conveying a plurality of containers; the container base is connected with the conveying rack; the driving component is used for driving the container base to autorotate; the container base comprises a container clamping end and a driving end, and whereinthe driving component comprises a motor and a clamping part driven by the motor; a slot matched with the driving end is formed in the clamping part; when the driving end moves into the slot and stays, the driving end is driven by the clamping part to rotate.

US Pat. No. 10,112,779

ALL-STEEL RECIPROCATING FLOOR SLAT SYSTEM

Keith Manufacturing Co., ...

1. A slat for use in a reciprocating floor slat conveyor system, comprising a slat portion that carries an upper load carrying surface, the slat portion having a pair of lateral side legs, with the side legs depending generally downwardly and then inwardly relative to the upper load carrying surface, and further, with each side leg terminating in a laterally inwardly directed foot portion, and with the foot portion of one side leg being upwardly vertically offset relative to the foot portion of the other side leg, and still further, with the upper load carrying surface including a lateral edge portion that extends a distance laterally outward relative to the one side leg that is upwardly vertically offset.

US Pat. No. 10,112,778

CONVEYOR DRIVE AND SYSTEM FOR UNIT HANDLING CONVEYORS

Nor-Tech Industrial Corp....

1. A conveyor system comprising:at least one zone, each zone including:
a plurality of rollers rotatably mounted to a conveyor frame,
a motor assembly having a rotor, a stator, a shaft and a motor housing, the rotor and the stator disposed within the motor housing, the motor housing having a first end and a second end, the shaft extending from the first end,
a motor drive controller disposed within a motor annex, the motor annex mounted to the second end of the motor housing, the motor drive controller mounted to an inside surface of a wall of the motor annex, and
a motor bracket affixed to the conveyor frame and to an outside surface of the wall of the motor annex, whereby the motor bracket provides a heat path to the conveyor frame for heat generated by the motor drive controller, the heat path not extending through the motor housing.

US Pat. No. 10,112,761

PACKAGE HAVING INTEGRAL TAB WITH FINGER HOLE OPENING FEATURE

Hollister Incorporated, ...

1. A package, comprising a sheet material having first and second side panels and upper and lower panels, the sheet material being wrapped into a three-dimensional configuration wherein the first and second side panels are placed in confronting relation to define a fin having a longitudinal free edge and opposed end free edges, at least a portion of the side panels parallel to the longitudinal free edge of the fin being adhered to one another to define a fin seal extending between the longitudinal free edge and a terminal line parallel to the longitudinal free edge, portions of the upper and lower panels being placed in confronting relation and said portions of the upper and lower panels being adhered to one another to define first and second end seals, and a starter line formed in the fin at a location intermediate the end free edges extending from the longitudinal free edge of the fin toward the upper panels wherein the starter line directs tearing of the package parallel to the longitudinal free edge.

US Pat. No. 10,112,758

PRODUCT PACKAGING CONTAINING A SOLID PRODUCT BLOCK

Ecolab USA Inc., Saint P...

1. A product packaging containing a solid product block for a dispenser system, comprising:a solid product block having a top, sides, and a bottom;
a handling means attached to the top of the solid product block and including a protective plate having an outside shape corresponding to the shape of the top of the solid product block; and
a wrapping means enclosing the solid product block and arranged between the top of the solid product block and the protective plate.

US Pat. No. 10,112,753

LID ATTACHMENT MEMBER

NIFCO INC., Yokosuka-shi...

1. A lid attachment member comprising:a metal plate that is equipped with an attachment hole to which a lid of a container is to be attached;
a raised or recessed seal portion that is formed at, and continuously all the way around, an outer peripheral portion of the metal plate; and
a resin member that is integrally formed on the outer peripheral portion of the metal plate, covers the seal portion, and has a back surface side that is configured to be welded to an open portion of the container, wherein
the seal portion is an annular groove formed at at least one of a front surface or a back surface of the metal plate, and
an angle between a groove bottom surface of the annular groove and a groove wall surface at an outer peripheral side of the annular groove is equal to or less than 90 degrees.

US Pat. No. 10,112,744

WIDE-NECKED PLASTIC CONTAINER FOR BULK MATERIAL, PRODUCED USING AN EXTRUSION-BLOW-MOLDING METHOD AND HAVING A CLOSURE CAP

20. A wide-necked extrusion blow-molded plastic container for bulk material, comprising:a closure cap configured for mounting on a container neck of a wide-necked plastic container opening;
a casing of the closure cap adjoining an outside wall of a body of the wide-necked plastic container; and
a number of locking projections distributed over a periphery of the container neck which project from an outside wall of the container neck, and which are arranged on the outside wall of the container neck, the closure cap being equipped with corresponding locking recesses, which during mounting of the closure cap on the container neck will engage with the locking projections to lock with one another in a non-detachable manner, the interacting locking projections and locking recesses being inaccessible in the mounted closure cap, the closure cap being configured to be removable after mounting only by destroying one or more of the locking recesses and/or locking projections;
wherein the locking projections are each configured as locking strips that extend in a peripheral direction and that interact with respective locking recesses, the locking recesses each being provided in a skirt that projects inward from an inside wall of the casing of the closure cap.

US Pat. No. 10,112,743

CONTAINER HAVING A BASE AND A LID

Swedish Match North Europ...

1. A container comprising a base; and a lid, wherein the lid comprises a first plurality of abutment projections spaced apart circumferentially on an inside surface of the lid configured to contact an upwardly facing abutment surface of a side wall of the base when the base and the lid are arranged parallel to each other and pressed together to form a closed container, and wherein the lid further comprises a second plurality of abutment projections spaced apart circumferentially on an inside surface of the lid and configured to contact an upwardly facing abutment of the side wall of the base when the base and the lid are arranged inclined to each other and pressed together.

US Pat. No. 10,112,739

METHOD OF PRODUCTION OF FABRIC BAGS OR CONTAINERS USING HEAT FUSED SEAMS

AMERIGLOBE, LLC, Lafayet...

1. A method of producing a flexible polypropylene fabric bulk bag, of the type that can hold 2,000 to 4,400 pounds of bulk material, with heat fused seams or joints that are stitch hole free, comprising:a. providing a plurality of highly oriented polypropylene woven fabric pieces, wherein at least one of said fabric pieces has a coated side with a bonding coating that has propylene elastomers, elastomers or combinations thereof and that is operable to form a seam or joint for the bag when melted, and wherein at least one of the fabric pieces has a coated side with a standard polypropylene fabric coating that is different from the bonding coating, the standard polypropylene fabric coating having a majority percentage of polypropylene and a small percentage of polyethylene;
b. forming an overlapped area by positioning the at least one fabric piece that has the coated side with the bonding coating so that the bonding coating faces the standard polypropylene fabric coating on the at least one fabric piece having said standard polypropylene fabric coating; and
c. applying heat and pressure to the overlapped area formed in step “b” to melt the bonding coating in the overlapped area and to form a bond between the bonding coating and the standard polypropylene fabric coating and a stitch hole free joint or seam for the bulk bag, wherein said bond has strength to maintain the said 2,000 to 4,400 pounds of bulk material within the bag without breaking and wherein the joint or seam has the following directly adjacent layers: (i) polypropylene fabric, (ii) bonding coating, (iii) standard coating; and (iv) polypropylene fabric; and
d. forming one or more additional overlapped areas as desired between selected fabric pieces to be joined of the plurality of highly oriented polypropylene woven fabric pieces, and applying heat and pressure to the one or more additional overlapped areas to form one or more bonds between standard polypropylene fabric and bonding coatings to establish one or more additional stitch hole free bag joints.

US Pat. No. 10,112,737

METHOD FOR THE MANUFACTURE OF AN ALUMINUM SHEET PRODUCT FROM USED BEVERAGE CONTAINERS

Golden Aluminum, Inc., F...

1. A method, comprising:forming a molten aluminum feedstock comprising at least about 65 wt. % used beverage containers, the used beverage containers having a body and an end, the end comprising a connector to a tab for opening the container, wherein the aluminum alloy of the body and the aluminum alloy of the end each comprise from about 0.55 to about 0.90 wt. % manganese, and wherein the aluminum alloy of the end has a higher magnesium concentration than the aluminum alloy of the body;
casting the molten aluminum feedstock to form a cast sheet; and
forming the cast sheet into an aluminum alloy sheet product.

US Pat. No. 10,112,727

ACTUATOR MONITORING SYSTEM USING INERTIAL SENSORS

Kitty Hawk Corporation, ...

1. A system, comprising:an interface configured to receive sensor data from an inertial measurement unit on a vehicle, wherein the vehicle includes a first rotor and a second rotor, both of which rotate about a vertical axis of rotation; and
a processor configured to:
determine an observed attitude and an observed rate of change in attitude of the vehicle based on the sensor data;
obtain a set of models of vehicle failure modes, wherein the set of models include: (1) a first model associated with a failure of the first rotor and (2) a second model associated with a failure of the second rotor;
determine a first expected attitude and a first expected rate of change in attitude of the vehicle based at least in part on the first model associated with a failure of the first rotor;
determine a second expected attitude and a second expected rate of change in attitude of the vehicle based at least in part on the second model associated with a failure of the second rotor;
identify a set of one or more malfunctioning rotors based on the observed attitude, the observed rate of change in attitude, the first expected attitude, the first expected rate of change in attitude, the second expected attitude, and the second expected rate of change in attitude; and
perform a responsive action based on the set of one or more malfunctioning rotors.

US Pat. No. 10,112,724

APPARATUS FOR PREVENTING SPARK PROPAGATION

The Boeing Company, Chic...

1. An aircraft, comprising:a fuselage, wings, and a hydraulic line passing through at least one of the wings;
a hydraulic joint for preventing spark propagation along the hydraulic line;
the hydraulic joint including a hydraulic fitting shaped to be positioned around a first hydraulic tube and a second hydraulic tube of the hydraulic line, the hydraulic fitting having an interior surface and a first open end for receiving the first hydraulic tube therein, wherein the interior surface of the hydraulic fitting defines an inner circumference; and
sealing material applied around the inner circumference of the interior surface, the sealing material having a shape that defines an opening that allows for the passage of leaks of hydraulic fluid from the joint within the hydraulic fitting but forms a mechanical barrier to propagation of sparks along the first and the second hydraulic tubes, the sealing material positioned on the interior surface of the hydraulic fitting adjacent the first open end.

US Pat. No. 10,112,715

SIGNALING PRINT SUBSTANCES

Hewlett-Packard Developme...

1. An unmanned aerial vehicle, comprising:an electromagnetic radiation (EMR) sensor to detect a signal indicative of a substance to be printed and corresponding to an image to be printed; and
a nozzle to eject the substance based on a location at which the signal is detected.

US Pat. No. 10,112,712

MULTI-USE UAV DOCKING STATION SYSTEMS AND METHODS

Amazon Technologies, Inc....

1. A method to deliver packages via an unmanned aerial vehicle (UAV), the method comprising:receiving a package at a facility;
mapping, via a central control, a first flight path for a first UAV from the facility to a final destination of the package;
sending instructions from the central control to the first UAV to follow the first flight path;
receiving, at the central control, weather data from one or more weather stations;
determining, by the central control and based on the weather data, that a weather event exists along the first flight path;
receiving, at the central control, a current position of the first UAV;
identifying, with the central control, an intermediate docking station from the current position of the first UAV;
mapping, via the central control, a second flight path for the first UAV from the current position to the intermediate docking station;
sending instructions from the central control to the first UAV to follow the second flight path to the intermediate docking station in response to determining the weather event exists along the first flight path;
sending instructions from the central control to the first UAV to hold at a landing platform at the intermediate docking station and at least one of: to receive a first energy source from a charging station at the intermediate docking station, to deposit the package at the intermediate docking station, or to receive a second package at the intermediate docking station;
determining, by the central control, a flight range of the first UAV, the flight range based at least in part on at least one of the first UAV receiving the first energy source, depositing the package, or receiving the second package;
mapping, via the central control and based at least in part on determining the flight range, a third flight path for the first UAV from the intermediate docking station to the final destination of the package; and
sending instructions from the central control to the first UAV instructing the first UAV to follow the third flight path.

US Pat. No. 10,112,694

SELF-RIGHTING AERONAUTICAL VEHICLE AND METHOD OF USE

1. A method of inspecting a structure using an aeronautical inspection vehicle, the method comprising steps of:obtaining the aeronautical inspection vehicle, the aeronautical inspection vehicle comprising:
a hollowed frame, the hollowed frame having a circular circumferential exterior surface,
at least one maneuvering and lift mechanism adapted to generate a lifting force, each of the at least one maneuvering and lift mechanism being assembled to a controller assembly, the controller assembly carried by a support element located within the interior of the hollowed frame,
a weighted mass assembled to one of (a) the hollowed frame and (b) the controller assembly in a manner enabling self-righting of the at least one maneuvering and lift mechanism during use, and
at least one inspection device for inspecting an object;
activating the aeronautical inspection vehicle;
placing the aeronautical inspection vehicle against a generally vertically oriented surface;
using the at least one maneuvering and lift mechanism to generate a lifting force, lifting the aeronautical inspection vehicle;
rolling the hollowed frame against the generally vertically oriented surface; and
acquiring inspection data.

US Pat. No. 10,112,690

WHEEL ATTACHMENT AND TOWING SYSTEM FOR A PONTOON WATER BIKE

1. A system for attaching wheels to a pontoon water bike, comprising in combination:said pontoon water bike having a plurality of transverse frame tubes with exposed ends spanning a plurality of spaced apart pontoons,
a plurality of cross tube receiver brackets coupled to the ends of a plurality of the transverse frame tubes, whereby a plurality of the cross tube receiver brackets are aligned longitudinally along each side of the pontoon water bike,
a plurality of side rails coupled to the cross tube receiver brackets aligned along each side of said pontoon water bike,
a plurality of sliding receiver brackets, with each sliding receiver bracket coupled to said side rail,
a plurality of wheel assemblies, with each wheel assembly coupled to each sliding receiver bracket, whereby the water bike is able to be wheeled over land.

US Pat. No. 10,112,658

SPOILER APPARATUS FOR RV VEHICLE

HYUNDAI MOTOR COMPANY, S...

1. A spoiler apparatus for an RV vehicle, comprising:a base housing having an opening at the rear thereof and installed at a rear of a vehicle;
a guide fitting installed in the base housing and coupled to a drive unit for transfer of power; and
a spoiler in slidable contact with the guide fitting;
wherein operation of the drive unit causes the spoiler to slidably extend rearward from the base housing along the guide fitting, and wherein continued operation of the drive unit causes the spoiler to tilt.

US Pat. No. 10,112,657

SUSPENSION SYSTEM FOR A CABIN OF A MINING VEHICLE

DUX MACHINERY CORPORATION...

1. A cabin for a mining vehicle, comprising:a cabin body having a plurality of interconnected walls and a floor attached to the walls, the walls and the floor defining an interior volume of the cabin body to receive within the interior volume an operator of the mining vehicle; and
a cabin suspension system having a plurality of suspension units to support the cabin body with respect to the mining vehicle, at least two of the suspension units being pivot suspension units, each pivot suspension unit being pivotably mountable to the cabin body and being fixedly mountable to the mining vehicle, the cabin body being pivotable relative to the mining vehicle about a common pivot axis defined by the pivot suspension units, each pivot suspension unit having an attenuation member to attenuate a pivot movement of the cabin body relative to the mining vehicle.

US Pat. No. 10,112,653

VEHICLE LOWER STRUCTURE

HONDA MOTOR CO., LTD., T...

1. A vehicle lower structure comprising:a front side frame;
a floor frame, wherein a front end of the floor frame is joined to a rear end of the front side frame;
a side sill disposed on an outer side of the floor frame in a vehicle-width direction;
an outrigger extending outward in the vehicle-width direction from the front side frame to a front end of the side sill;
a reinforcing member extending obliquely rearward and inward in the vehicle-width direction from a junction area between the outrigger and the side sill to the front side frame,
wherein the reinforcing member includes a bent portion bent upward at an intermediate position thereof,
wherein the vehicle lower structure further comprises:
a front assembly including the front side frame and the outrigger; and
a floor assembly including the side sill, the floor frame, and a floor panel supported by the side sill and the floor frame, and
wherein the reinforcing member is joined to lower surfaces of the front side frame and the outrigger of the front assembly, and is joined to lower surfaces of the side sill and the floor panel.

US Pat. No. 10,112,623

SENSORY STIMULATION SYSTEM FOR AN AUTONOMOUS VEHICLE

Uber Technologies, Inc., ...

1. A sensory stimulation system for an autonomous vehicle (AV), the sensory stimulation system comprising:at least one display unit within an interior of the AV;
one or more processors; and
one or more memory resources storing instructions that, when executed by the one or more processors, causes the sensory stimulation system to:
determine a set of maneuvers to be executed by the AV;
based on each respective maneuver of the set, determine a set of visual stimulation outputs to provide a passenger of the AV with visual indications of the respective maneuver; and
prior to the AV executing the respective maneuver, preemptively display the set of visual stimulation outputs on the at least one display unit.

US Pat. No. 10,112,621

WEARABLE DEVICE, VEHICLE FOR COMMUNICATING WITH THE WEARABLE DEVICE

HYUNDAI MOTOR COMPANY, S...

1. A wearable device comprising:a communicator configured to perform a communication with a vehicle;
a detector configured to detect a user's biological information; and
a controller configured to perform a power save mode when vehicle speed information is received via the communicator, convert the power save mode into a normal mode when first determination information of drowsy driving is received via the communicator during the power save mode, secondly determine whether current driving is a drowsy driving based on the detected biological information during the normal mode, and when the drowsy driving is determined, allow second determination information of drowsy driving to be transmitted to the vehicle so that the second determining information is output from the vehicle,
wherein the first determination information of drowsy driving is information transmitted from the vehicle.

US Pat. No. 10,112,618

TRAFFIC POLLUTION INDICATOR

Rimalu Technologies, Inc....

1. A traffic pollution indicator for a vehicle comprising:one or more uncalibrated sensors that output a signal varying with time, representing variations in an aggregate concentration of gases with time of one or more types of pollution, without carrying at any time any information on any absolute gas concentration;
a microcontroller that receives the signal and generates a digital representation of the signal;
a wireless communication device that transmits the digital representation to a display device;
an enclosure housing at least the microcontroller; and
a mount attached to the enclosure and comprising one or more air vent engagement elements for attaching the enclosure to an air vent of the vehicle;
wherein the display device comprises a screen and receives the digital representation from the wireless communication device and presents a visual representation of the digital representation on the screen;
wherein the signal is only generated when at least one of the variations in the aggregate concentration exceeds a predefined or calculated threshold.

US Pat. No. 10,112,590

VALVE UNIT FOR MODULATING PRESSURE IN AN AIR-BRAKE SYSTEM

WABCO GmbH, Hannover (DE...

1. A valve unit (1) for modulating pressure in a compressed air braking system, the valve unit comprising:a brake pressure input (3),
a brake pressure output (4) and a purge output (5),
an inlet valve (6) configured as a diaphragm valve,
an outlet valve (7) configured as a diaphragm valve,
for each of the diaphragm valves (6, 7), respective precontrol valves (8, 9) which are each configured as a 3/2-way solenoid valve,
an elongate valve housing (2) that is divided by a division plane (10) extending horizontally in an installation position into a base housing (11) and a housing cover (12), wherein the brake pressure input (3) and the brake pressure output (4) and the purge output (5) are arranged in the valve base housing (11), the diaphragm valves (6, 7) are arranged behind each other in the longitudinal direction (13) in the base housing (11) between the brake pressure input (3) and the brake pressure output (4), with parallel actuation axes (14, 15) and with an arrangement of diaphragms (16, 17) associated with the diaphragm valves in a common diaphragm plane parallel to and proximate to the division plane (10) and clamped between the base housing (11) and the housing cover (12), and wherein the precontrol valves (8, 9) are arranged in the housing cover (12), and
a silencer (75) at the purge output (5), the silencer including a cylindrical silencer housing (76) with an inlet opening (77), a calming chamber (78) arranged radially inside the silencer, a large outlet opening (79) and a silencer insert (80.1, 80.2) arranged upstream of the outlet opening (79) inside the silencer housing (76) and made of an air-permeable and sound-deadening material, wherein the silencer (75) is attached to the base housing (11) with base walls (83, 84) oriented parallel to the division plane (10) between the brake pressure input (3) and the brake pressure output (4).

US Pat. No. 10,112,578

ELECTRICAL STEERING COLUMN LOCK FOR AN AUTOMOTIVE VEHICLE

U-SHIN DEUTSCHLAND ZUGANG...

1. An electrical steering column lock for an automotive vehicle capable of locking and unlocking a steering column comprising:a bolt capable of moving for locking and for unlocking the steering column;
a cam wheel intended to rotate according a first rotation axis and to cooperate with the bolt for controlling the bolt movement; and
an assembly for determining the rotation position of the cam wheel while the cam wheel is rotating;
wherein the assembly for determining the rotation position of the cam wheel comprises a Hall effect position sensor and a magnet;
wherein the magnet is a disc with several blades protruding in a radial direction, to enable the magnet to closely follow the rotation of the cam wheel.

US Pat. No. 10,112,544

VEHICLE ARMREST ASSEMBLY

Shanghai Yanfeng Jinqlao ...

1. A component for a vehicle interior comprising:(a) a base comprising (1) a first divider configured to form a main compartment and a first side compartment and (2) a second divider configured to form the main compartment and a second side compartment;
(b) a cover configured to enclose the main compartment;
(c) a first door configured to enclose the first side compartment; and
(d) a second door configured to enclose the second side compartment;
wherein the cover is configured to extend between the first divider and the second divider and move along the first divider and the second divider to uncover the main compartment.

US Pat. No. 10,112,541

LOW-FLOOR DROP FRAME FOR PASSENGER TRANSPORT VEHICLE

Champion Bus, Inc., Imla...

1. A vehicle for transporting passengers comprising:a chassis that includes a front axle, a rear axle, and a frame comprising a front section that supports said front axle and a rear section that supports said rear axle; and
a drop frame insert located between said front section of said frame and said rear section of said frame,
wherein said drop frame insert comprises a longitudinally-extending left rail and a longitudinally-extending right rail, wherein said left rail and said right rail are spaced apart and extend in generally parallel relationship,
wherein a top surface of each of said left rail and said right rail of said drop frame insert is positioned lower than a top surface of said frame, and wherein at least a portion of a bottom surface said drop frame insert is generally coplanar with a bottom surface of said frame,
wherein said drop frame insert includes a reinforcement assembly positioned at a rear end of each of said left rail and said right rail, wherein said reinforcement assemblies are configured to be engaged with said rear section of said chassis frame.

US Pat. No. 10,112,521

SNOW-CAT WITH INCREASED FUNCTIONALITY

SNOOD S.R.L., Vipiteno (...

1. A snow-cat configured for piste grooming, the snow cat comprising:two tracks;
a front driving cab;
a support structure coupled to the front driving cab and at least partially positioned above the two tracks; and
a cabin positioned on the support structure and comprising a galley for preparing and serving food products or beverages.

US Pat. No. 10,112,520

TEMPERATURE MEASURING DEVICE AND TRANSPORT VEHICLE SKIP

MOBA Mobile Automation AG...

1. A temperature measuring device comprising:a temperature sensor, arranged within a holder, for determining the temperature of a building material located within a skip of a transport vehicle, the skip comprising an inner wall and an outer wall, and the holder being arranged on that side of the inner skip wall that faces the outer skip wall,
wherein
the holder is arranged within a recess within the inner skip wall such that it is thermally insulated from the inner skip wall, and
the holder is arranged within the recess such that a region, which faces the interior of the skip, of the holder is exposed.

US Pat. No. 10,112,508

HARNESS BOOSTER CAR SEAT CONVERTIBLE TO MULTIPLE SEPARATELY USABLE CONFIGURATIONS

EVENFLO COMPANY, INC., M...

1. A harness booster car seat comprising:a backrest booster having a seating surface thereon and a locking mechanism for releasably locking the backless booster thereto;
a backless booster capable of use independently from the backrest booster having a seating surface and an opening therein for slidingly receiving the seating surface of the backrest booster therein such that substantially all of the backrest booster seating surface is covered by the seating surface of the backless booster and an aperture through the seating portion thereof for receiving a center strap therethrough.

US Pat. No. 10,112,500

AUTOMOBILE QUICK CHARGE CONTROL DEVICE

1. An automobile quick charge control device, comprising:an electric vehicle body, comprising a power generator;
a power storage module, installed at the electric vehicle body, and electrically coupled to the power generator, and having at least a first battery assembly and a second battery assembly coupled in parallel with each other, and the first battery assembly and the second battery assembly having a plurality of battery units and a plurality of node switches respectively, and each battery unit being formed by coupling a plurality of batteries in series with one each;
a battery management system, electrically coupled to the power storage module and the power generator, and also electrically coupled to each node switch of the first battery assembly and the second battery assembly; and
a vehicle controller, electrically coupled to the power storage module, the power generator and the battery management system, for reading information of the battery management system and monitoring the power storage module, and controlling the switch of charge/discharge of the first battery assembly and the second battery assembly;
wherein the node switch is installed between the adjacent battery units, and both ends of the first battery assembly and the second battery assembly are coupled to the node switches respectively.

US Pat. No. 10,112,494

EV CONNECTOR HAVING VISUAL INDICATOR

CHARGE-AMPS AB, Stockhol...

1. An electric vehicle connector configured for charging an electric vehicle via an electric vehicle plug receptacle, said electric vehicle connector comprising:a body having
a first plug end configured to be coupled to the electric vehicle plug receptacle on the electric vehicle for charging; and
a second power cable end configured to be coupled to a power cable,
wherein the first end includes a terminal interface having one or more terminal receptacles for receiving one or more terminals positioned within the electric vehicle charging receptacle,
wherein the first plug end also includes a transparent visual indicator part having one or more light sources, and
wherein the transparent visual indication part encircles the one or more terminal receptacles to allow for viewing of the one or more light sources regardless of position of a viewer relative to the transparent visual indicator part.

US Pat. No. 10,112,490

HIGH VOLTAGE DEVICE FOR A RAIL VEHICLE

Siemens Aktiengesellschaf...

1. A high voltage device for a vehicle which at least during driving operation is supplied with electrical energy from a power system providing a high voltage, the high voltage device comprising:a main power switching unit;
at least one high voltage component, which by means of said main power switching unit can be electrically connected to the power system, and having at least one active section;
said at least one high voltage component being a voltage conversion device which serves, starting from the high voltage provided by the power system, to provide a voltage different therefrom;
a grounding switching device having at least one switch configured to assume a grounding position in which said switch grounds an electrical connection between said active section and said main power switching unit; and
said at least one high voltage component having a housing formed with a receiving region in which said switch is accommodated at least in said grounding position that grounds said at least one active section of said high voltage component, said housing enclosing said at least one active section of said at least one high voltage component.

US Pat. No. 10,112,484

THROTTLE PEDAL

Orscheln Products L.L.C.,...

1. A throttle pedal assembly comprising:a unitary, one-piece housing having a first side wall, a second side wall, a top wall, a bottom wall, a front wall and a back wall which, in combination, define a main chamber and a sensor cavity adjacent said main chamber; said sensor cavity being separated from said main chamber by a common wall which isolates said sensor cavity from said main chamber; the main chamber being open to the front and bottom of the housing and being defined in part by the first side wall and common wall which are opposite each other; and the sensor cavity being open to the top wall and being defined in part by the second side wall and the common wall; said main chamber comprising a through hole in said side first wall and a blind bore in said common wall which is co-axial with said opening in said first wall;
a pedal assembly comprising a pedal, a pedal arm, and a head at an end of the pedal arm, the head being sized to be inserted into the housing main chamber; said head defining a passage which extends through said pedal head;
a pedal shaft, separate from said pedal assembly, sized to extend though said opening in said first wall of said housing, through said head passage, and to be received in said blind bore of said common wall; whereby said pedal shaft mounts said pedal assembly in said main chamber for pivotal motion of said pedal assembly relative to said main chamber about a pivot axis defined by said pedal shaft; said pedal shaft and said pedal assembly head being configured to be snappingly connected together; whereby said pedal assembly is being rotationally fixed relative to said pedal head and whereby said pedal assembly is mounted in said housing without the use of tools;
a magnet positioned on said pedal shaft such that when said pedal shaft is mounted in said housing, said magnet will be in said blind bore; said magnet being coaxial with said pivot axis such that said magnet rotates on said pivot axis as said pedal assembly rotates about said pivot axis;
a Hall effect sensor assembly mounted in the sensor cavity; the Hall effect sensor having a Hall chip; the cavity and Hall effect sensor assembly being respectively shaped, sized, and positioned in said sensor cavity such that the Hall chip is aligned with said pivot axis such that the Hall chip and the magnet lay on a common axis, and whereby the magnet rotates about the pivot axis relative to; and
a seal which closes the sensor cavity to prevent contaminants from entering the cavity.

US Pat. No. 10,112,483

HYDRAULIC PUMP ASSEMBLY WITH FORWARD DRIVESHAFT CLEARANCE

HHG Holdings, LLC, Houst...

1. A vehicle mounted hydraulic pump assembly, comprising:a gearbox configured to be connected to a power take-off driven by a transmission of a four-wheel drive vehicle, the gearbox comprising:
a housing;
a plurality of vertically aligned gears contained within the housing, the plurality of gears including an input drive gear, at least one idler gear, and an output gear, the input drive gear being a same size as the output gear;
a pair of ball bearings associated with each gear;
an input shaft associated with the input drive gear;
an output shaft associated with the output gear, the output shaft being a female spline shaft configured to be disposed below a forward driveshaft associated with the transmission; and
a hydraulic pump connected to the gearbox and configured to be disposed forward of a transfer case associated with the transmission.

US Pat. No. 10,112,472

DRIVE DEVICE FOR HYBRID VEHICLE

TOYOTA JIDOSHA KABUSHIKI ...

1. A drive device for a hybrid vehicle, the hybrid vehicle including an engine, a motor, the engine and the motor being arranged on different rotational axes, and a drive wheel,the drive device comprising:
a driven gear shaft arranged to rotate about the rotational axis shared with a rotor shaft of the motor, the driven gear shaft being connected to the rotor shaft of the motor in a manner capable of power transmission to the rotor shaft of the motor, and the driven gear shaft extending in a shaft direction toward a rotor shaft side;
a first bearing configured to support the rotor shaft to allow rotation of the rotor shaft;
a second bearing arranged on the driven gear shaft, the second bearing being arranged in a portion on the rotor shaft side of the driven gear shaft;
a driven gear configured such that power from the engine is transmitted to the driven gear,
the driven gear being provided on the driven gear shaft; and
an output shaft arranged to be rotatable about the rotational axis shared with the rotor shaft of the motor, the output shaft being connected to the rotor shaft in a manner capable of power transmission to the rotor shaft, and the output shaft being connected to the drive wheel in a manner capable of power transmission to the drive wheel, wherein
the rotor shaft, the driven gear shaft, and the output shaft are different shafts from each other, and
the power from the engine is transmitted through the driven gear shaft, the rotor shaft, and the output shaft to the drive wheel.

US Pat. No. 10,112,461

PHOTOCATALYST DEVICE AND AIR CONDITIONER FOR VEHICLE HAVING THE SAME

HANON SYSTEMS, Daejeon (...

1. A photocatalyst device comprising:a body;
a first light source part including a substrate and an LED coupled to the substrate, the first light source part configured to irradiate ultraviolet light;
a catalyst part coupled to the body, the catalyst part configured to conduct a photocatalytic reaction with the ultraviolet light irradiated by the first light source part to generate a plurality of superoxygen radicals; and
a heat radiating part disposed on the first light source part, the heat radiating part configured to radiate the heat generated by the first light source part, wherein the heat radiating part includes a first radiating fin member disposed on a first side of the substrate, the first radiating fin member extending from the substrate in a direction toward the catalyst part.

US Pat. No. 10,112,435

METHOD OF MANUFACTURING FOLDERS HAVING UNDER-DIMENSIONS, A MACHINE FOR SUCH A MANUFACTURE, AND A CASSETTE FOR SUCH A MACHINE AND SUCH A MANUFACTURING METHOD

Bindomatic AB, Stockholm...

1. A method of manufacturing a first folder having a first width dimension using a folder manufacturing machine configured to manufacture a second folder having a second width dimension that is greater than the first width dimension, the first folder comprising a cover having two cover sides, a back between the cover sides, an adhesive on the inside of the back, and a bundle of sheets inserted between the two cover sides of the cover and one side edges of which are brought into abutment against the inside of the back and the adhesive, the method comprising:activating the adhesive by an activation device of the folder manufacturing machine for a predetermined time for the adhesion of the bundle of sheets of said first folder to the inside of the back; and
while the adhesive is activated for the adhesion of the bundle of sheets to the inside of the back, continuously or intermittently feeding the first folder through the folder manufacturing machine by a conveyer adapted to the second folder having the second width dimension, wherein said first folder is placed in a cassette having an inner dimension corresponding to said first width dimension and having an outer dimension corresponding to said second width dimension, and the cassette is moved through the folder manufacturing machine by said conveyer.

US Pat. No. 10,112,397

LIQUID JETTING APPARATUS

BROTHER KOGYO KABUSHIKI K...

1. A liquid jetting apparatus configured to jet liquid toward a recording medium, comprising:a liquid jetting head including a liquid jetting surface and a plurality of nozzles arranged in the liquid jetting surface;
a carriage on which the liquid jetting head is mounted, and which is movable along a guide rail extending in a first direction parallel to the liquid jetting surface;
a cap configured to cover the plurality of nozzles;
a cap switching device configured to move the cap relative to the liquid jetting head in a second direction crossing the liquid jetting head and to perform switching between a capping state and an uncapping state, the capping state being a state in which the cap is in contact with the liquid jetting head to cover the plurality of nozzles, and the uncapping state being a state in which the cap is separated away from the liquid jetting head;
a carriage blocker configured to move between a first position at which the carriage blocker is not in contact with carriage, and a second position at which the carriage blocker is in contact with the carriage to block movement of the carriage in the first direction; and
a contacting portion which is located, in the uncapping state, at a third position at which the contacting portion is not in contact with carriage, and which is located, in the capping state, at a fourth position at which, under a condition that the carriage, of which movement in the first direction is blocked by the carriage blocker located at the second position, rotates around an axis perpendicular to the liquid jetting surface with the carriage blocker as a supporting point, the contacting portion is capable of contacting the rotating carriage,
wherein the contacting portion is configured to move integrally with the cap in a plane parallel to the liquid jetting surface.

US Pat. No. 10,112,378

METHOD OF MANUFACTURING ANTI-THEFT LABELS

Chem Etch Manufacturing I...

1. A method of manufacturing a marking strip for delivering an adhesive to a flat surface, the method comprising:providing a strip element removably joined to a liner element, the strip element comprising a laminate top coat, a film layer and an adhesive layer;
treating the strip element by removing at least one area of the liner element, removing at least one area of the film layer and removing at least one area of the adhesive layer, wherein the area removed from the liner element, the area removed from the film layer, and the area removed from the adhesive layer are substantially congruent with one another; and
separating the treated strip element from a sheet of other strip elements;
wherein the sheet has a longitudinal axis and a lateral axis, and the sheet is systematically drawn through a protective housing by a longitudinal force imposed along the longitudinal axis after one or more strip elements is treated, while a lateral force is imposed along the lateral axis, thereby reducing a risk of fire during treatment.

US Pat. No. 10,112,344

MACHINE FOR REMOVING SUBSTRATE MATERIAL, FOR WASHING, AND FOR DRYING PARTS PRODUCED BY A 3-D PRINTER

Audubon Machinery Corpora...

1. A machine for processing a part produced by a 3-D printer, the part having a substrate, the machine comprising:a housing having a working chamber defined therein;
a support structure disposed at the bottom of the working chamber for supporting the part, the support structure having at least one opening defined therein;
a spray header disposed along at least a portion of the perimeter of the working chamber;
a pump configured and arranged to convey a washing fluid and a rinsing fluid at varying pressures through the spray header, wherein the washing fluid has chemical properties suitable for dissolving at least a portion of the substrate;
a heater for warming one or more of the washing and rinsing fluid;
wherein the fluid contacts the part and then passes through the opening in the support structure where it flows to the bottom of the working chamber to a fluid outlet; and,
wherein the spray header comprises an assembly of vertical and horizontal tubes having apertures defined therein.

US Pat. No. 10,112,328

FUEL TANK MADE OF POLYKETONE AND METHOD OF MANUFACTURING THE SAME

JPC Automotive Co., Ltd.,...

1. A method of manufacturing a fuel tank using polyketone, comprising:injection-molding an upper cover and a lower cover using an injection-molding machine;
placing the upper cover and the lower cover, injection-molded in the injection-molding, at a relatively high position and a relatively low position, respectively, and assembling the upper cover and the lower cover with each other; and
bonding contact surfaces between the upper cover and the lower cover, assembled with each other in the assembling, to each other using a laser beam,
wherein the upper cover and the lower cover, injection-molded by the injection-molding machine, are made of polyketone so as to improve rigidity thereof,
the method further comprises pressurizing an outer side surface of at least one of the upper cover and the lower cover using at least one roller between the assembling and the bonding,
the bonding is performed while the roller pressurizes the outer side surface of at least one of the upper cover and the lower cover in the pressurizing,
the upper cover and the lower cover have edges having shapes corresponding to each other such that one of the upper cover and the lower cover has a protruding portion formed on the edge thereof and a remaining one has an insertion recess formed in the edge thereof, into which the protruding portion is fitted, and
each of the protruding portion and the insertion recess has at least one support surface formed in one side surface thereof, the support surface being parallel to outer side surfaces of the upper cover and the lower cover so as to support a pressurization force of the roller pressurizing the outer side surface of at least one of the upper cover and the lower cover in the pressurizing,
wherein the injection-molding includes injection-molding an intermediate cover, the intermediate cover having insertion recesses formed therein, into which a lowermost edge of the upper cover and an uppermost edge of the lower cover are fitted,
the assembling includes assembling the intermediate cover between the upper cover and the lower cover, and
the bonding includes bonding contact surfaces between the upper cover and the intermediate cover to each other and bonding contact surfaces between the lower cover and the intermediate cover to each other using the laser beam.

US Pat. No. 10,112,310

FOOD HANDLING GRIPPER

SOFT ROBOTICS, INC., Cam...

1. A robotic system comprising:a soft actuator comprising an elastomeric bladder configured to receive an inflation fluid;
a securing mechanism comprising a body and one or more extensions, the one or more extensions configured to be received in one or more corresponding recesses of the elastomeric bladder and to be gripped within the recesses upon application of a tightening force to seal the inflation fluid in the soft actuator; further comprising a base having one or more rounded fingers from gripping an inflation fluid supply line.

US Pat. No. 10,112,296

REMOTE MANIPULATION INPUT DEVICE

BBZ S.R.L., Vigasio (VR)...

1. A multidimensional input device comprising an anthropomorphic arm with a handpiece which can be grasped by an operator configured to interact with a scenario represented in a display unit, said handpiece being removably associable to a terminal section of said anthropomorphic arm through a magnetic coupling spherical joint, wherein the handpiece comprises:an inertial platform comprising an accelerometer, a gyroscope and a magnetometer;
a gripper provided for the operator.

US Pat. No. 10,112,283

METHOD FOR CLEANING TANK MELTING FURNACES FOR MAKING GLASS ITEMS

FARE S.R.L., Dolo (IT)

1. A method for cleaning a regenerator of a tank melting furnace for making glass items, wherein the tank melting furnace comprises a melting chamber, which has a melting tank to which a regeneration chamber is connected, wherein the regeneration chamber comprises a regenerator comprising a supporting structure for layers of refractory bricks, which are superimposed in a staggered arrangement so as to determine descent paths for the descent of the cooling exhaust gases that arrive from said melting chamber, said cleaning method comprising sandblasting said exhaust gas descent paths during operation of the melting furnace, wherein said sandblasting comprises inserting a sandblasting delivery pipe successively through openings of the regeneration chamber and into the exhaust paths from either a base or a top of the regenerator, wherein the sandblasting delivery pipe is supplied with a mixture of compressed gas and abrasive material, and wherein the delivery pipe is contained in a second pipe that is cooled with air or water while the sandblasting is being performed.

US Pat. No. 10,112,249

BRAZE ALLOY LAYERED PRODUCT

ALFA LAVAL CORPORATE AB, ...

1. A method for providing a braze alloy layered product comprising the following steps:applying a mechanical blend on at least a part of a surface of a substrate, wherein the mechanical blend is a mechanical blend of at least one powder of particles of a silicon source, in which each particle is of a silicon source, and at least one powder of particles of a boron source, in which each particle is of a boron source, wherein the particles have an average particle size less than 250 ?m wherein the at least one boron source and the at least one silicon source are oxygen free except for inevitable amounts of contaminating oxygen, wherein the amount of inevitable amount of oxygen is less than 10 wt %, and wherein the weight ratio in the blend of boron and silicon is within a range from about 3:100 to about 100:3, and wherein silicon and boron are present together in the blend in at least 35 wt %, and wherein the substrate comprises a parent material having a solidus temperature above 1100° C.;
heating the substrate having the applied boron source and the applied silicon source to a temperature lower than the solidus temperature of the parent material of the substrate to form a braze alloy; and
cooling the substrate having the applied boron source and the applied silicon source, and obtaining a layer of braze alloy on the substrate, wherein the layer of braze alloy comprises the silicon source, the boron source and the elements of the parent material, wherein the braze alloy layer has a melting point lower than the parent material;
wherein the silicon source is one or more of elemental silicon, an alloy containing silicon, or a compound containing silicon; and
wherein the boron source is one or more of elemental boron, an alloy containing boron, or a compound containing boron.

US Pat. No. 10,112,216

SYSTEMS, DEVICES AND METHODS FOR SORTING ITEMS

United States Postal Serv...

1. A system for sorting items, the system comprising:a pocket, the pocket comprising a receiving surface, a sidewall located along a first side of the receiving surface, and a paddle moveably coupled with the sidewall;
an injector disposed proximate the pocket, the injector configured to inject a first plurality of items along a path toward the pocket to form a first stack in the pocket; and
a progressive displacement system comprising:
a body;
a linear member moveably coupled to the body, the linear member moveable in a first direction and a second direction;
a gear system rotatably coupled with the body and in mechanical communication with the linear member, wherein movement of the linear member is translated to rotational movement of the gear system; and
a divider in mechanical communication with the gear system, the divider having a first side and a second side opposite the first side, wherein the rotational movement of the gear system due to movement of the linear member moves the divider between a retracted position and an extended position, wherein a corresponding output movement distance of the divider is greater than an input movement distance by the linear member.

US Pat. No. 10,112,201

METHOD AND APPARATUS FOR CLEANING A MACHINE EMPLOYING PERMANENT MAGNETS TO REMOVE FERROUS METALS FROM A FLOW OF MATERIAL

DRP VENTURES INC., Kelow...

1. A magnet cleaner cooperating with a conveyer carrying pieces of metal in non-ferrous material, the magnet cleaner comprising:a frame, at least one permanent magnet positionably mounted on the frame so as to be selectively elevatable between a lowered position and a raised position upon actuation of an actuator, wherein the actuator is positioned so as to cooperate with the permanent magnet and the frame,
a capture sheet mounted to the frame and positioned on the frame so as to be substantially flush with the at least one permanent magnet when in the lowered position, and spaced by an attenuation distance from the at least one permanent magnet when in the raised position,
a parasitic energy scavenger mounted so as to engage the conveyer, wherein translation of the conveyer imparts energy from the conveyer to the energy scavenger,
an energy converter cooperating with the energy scavenger and the actuator so as to selectively drive the actuator to thereby position the at least one permanent magnet between the lowered and raised positions, and wherein the energy converter charges a battery and the actuator is electrically driven by the battery,
whereby, when the at least one permanent magnet is in the raised position the attenuation distance to the capture sheet is sufficient to allow release of ferrous metals collected to an underside of the capture sheet; captured from material on the conveyer belt when the at least one permanent magnet is in the lowered position.

US Pat. No. 10,112,194

DETECTION OF MICROSCOPIC OBJECTS

Q-linea AB, Uppsala (SE)...

1. A detection disc for carrying samples in an apparatus for detection of microscopic objects in a fluid, the detection disc including a detection channel and a separate focus structure, wherein the focus structure comprises a groove located outside of the detection channel, said groove comprising sloping sidewalls provided in a first surface of the detection disc, wherein an angle between each sidewall of the groove and the first surface is greater than a critical angle of the detection disc such that when the detection disc is illuminated with a light beam that enters the detection disc from a second surface that is opposite the first surface, light from the light beam is internally reflected by said sidewalls of said groove and light from the light beam is transmitted through a bottom of said groove to a greater extent as compared to said sidewalls to allow for contrast-based focusing between the bottom of the groove and the sidewalls of the groove.

US Pat. No. 10,112,193

FABRICATION OF A MICROFLUIDIC CHIP PACKAGE OR ASSEMBLY WITH SEPARABLE CHIPS

International Business Ma...

1. A method of fabrication of a microfluidic chip package or assembly (1), comprising:providing (S1) a substrate (10, 30) having at least one block (14, 14a) comprising one or more microfluidic structures on a face (F) of the substrate; and
partially cutting (S2) into the substrate to obtain partial cuts (10c), such that a residual thickness (10r) of the substrate at the level of the partial cuts (10c) enables singulation of said at least one block (14, 14a);
cleaning (S4) said at least one block; and
applying (S5-S7) a cover-film (62) to cover said at least one block (14, 14a), whereby at least one covered block is obtained, the applied cover film sealing the microstructures in each said at least one block and still enabling singulation of each covered block, wherein each covered block corresponds to a microfluidic chip after singulation.

US Pat. No. 10,112,164

TRAY DECK ORIFICE DEVICE AND METHODS OF REPAIRING A TRAY DECK

Woven Metal Products, Inc...

1. A method of repairing a damaged tray deck for use in a vessel, comprising the steps of:providing at least one tray deck orifice repair device each comprising a flat member having a defined thickness and a void at a center thereof; and
coupling the at least one tray deck orifice repair device to an upper surface of the damaged tray deck such that void of each of the at least one tray deck repair devices is aligned with each of the plurality of orifices on the tray deck,
wherein the at least one tray deck orifice repair device has at least one anti-spin tab extending from an edge thereof, and wherein the at least one tray deck orifice repair device is coupled with a valve.

US Pat. No. 10,112,160

CHEMICAL MIXING AND PUMPING UNIT AND METHODS FOR OILFIELD OPERATIONS

Premier Coil Solutions, I...

1. A chemical mixing and pumping unit for oilfield operations, the unit comprising:at least one mixing tank onboard the chemical mixing and pumping unit, the mixing tank comprising:
one or more mixing paddles within the mixing tank;
one or more water inlets located near the bottom of the mixing tank through which water enters the mixing tank and is directed toward the one or more mixing paddles; and
one or more chemical inlets through which one or more chemicals enter the mixing tank;
one or more storage tanks capable of storing chemicals onboard the chemical mixing and pumping unit; and
one or more pumps corresponding to the individual storage tanks capable of delivering chemicals from the storage tanks to the one or more chemical inlets in the at least one mixing tank.

US Pat. No. 10,112,141

PURIFICATION COLUMN

1. A purification column in which a fluid is purified by flow through a purifying component, the purification column comprising:an annular wall defining a bore which, in use, contains the purifying component;
an inlet port opening to the bore, said inlet port comprising a first aperture through said annular wall, said inlet port being adjacent one end of the purification column;
an outlet port opening from the bore, said outlet port comprising a second aperture through said annular wall, said outlet port being adjacent the one end of the purification column;
a flow guidance device within said bore and removably connected to said inlet port and said outlet port so as to guide the fluid to the purifying component from said inlet port and so as to guide the fluid from the purifying component to said outlet port, the flow guidance device maintaining separation of the fluid flows to and from the purifying component; and
wherein said annular wall is an extruded body.

US Pat. No. 10,112,137

MARINE ENGINE STRAINER ASSEMBLY

Indmar Products Company I...

1. A strainer assembly for a marine engine, the strainer assembly comprising:a housing having an upstream end, a downstream end and an internal cavity therebetween, the downstream end of the housing having a flush port and an outlet;
a strainer removably located inside the internal cavity of the housing;
a housing cover assembly removably secured to the upstream end of the housing, the housing cover assembly comprising a cover having an inlet adapted to introduce water into the internal cavity of the housing and a retainer for securing the position of the cover wherein said strainer may be removed from the internal cavity of the housing upon removal of the housing cover assembly;
a plug having a first portion adapted to fit inside the flush port and a second portion having external threads wherein said plug may be secured in place by a rotatable collar having internal threads adapted to engage the exterior threads of the second portion of the plug to close the flush port wherein said rotatable collar may be loosened and said plug removed from said flush port of said housing and an end of a garden hose secured to the flush port of the housing to flush the marine engine.

US Pat. No. 10,112,136

FLUID LUBRICANT AND MATERIAL SHAVINGS RECAPTURE SYSTEM FOR A CUTTING OPERATION

Enviro-Fab LLC, Kennewic...

1. A cutting fluid lubricant circulation system comprising:a catch basin positioned below a work piece for capturing cutting fluid and material remnants from said work piece, said catch basin having a drain;
a filter element within said drain, said filter element removing particles and debris from the cutting fluid as it drains from the catch basin into a drain block, thereby producing filtered cutting fluid;
a reservoir fluidically connected to said drain block for collecting said filtered cutting fluid, wherein filtered cutting fluid flows from said drain block through a hose into said reservoir which is below said catch basin; and
a fluid pump fluidically connected to said reservoir for evacuating said reservoir, said fluid pump pumping said filtered cutting fluid through a second filter element positioned at a reservoir fluid outlet to a hose to a valve to meter filtered cutting fluid onto said work piece.

US Pat. No. 10,112,131

WASTE SCREENING APPARATUS

ESSA CORP., Gyeongju-si ...

1. A waste screening apparatus comprising:a main body disposed in a water flow channel in a water treatment plant, wherein the main body is vertically elongate and tilted;
a waste screener vertically and tiltedly disposed in the main body to screen wastes in input water and to allow waste-removed water to be discharged through water discharge holes of the main body, wherein the waste screener vertically circulates in a conveyor manner, wherein the input water is input to a front, rear and bottom of the waste screener;
a driver to move the waste screener using a roller chain thereof; and
a brusher disposed to substantially contact a surface of the waste screener to remove a waste from the waste screener,
wherein the main body includes:
left and right wing plates disposed at left and right front sides of the main body respectively, wherein the left and right wing plates are water-tightly coupled to left and right inner side walls of the water flow channel, respectively, to guide the input water to the waste screener;
left and right side walls having the water discharge holes defined therein respectively to allow waste-removed water to be discharged out from the waste screener therethrough;
a rear blocking wall disposed at a rear of the waste screener to be spaced from the waste screener; and
a waste-discharge port disposed at a top of the main body at a rear of the rear blocking wall to allow wastes filtered by the waste screener to be discharged out therethrough,
wherein the input water passes through front and rear portions of the waste screener with wastes being removed from the input water, and, then, is discharged out through the water discharge holes defined in the left and right side walls respectively.

US Pat. No. 10,112,127

METHOD FOR CONTROLLING FLOW VOLUME OF COAL/KEROSENE SLURRY, AND APPARATUS FOR PRODUCING UPGRADED BROWN COAL

Kobe Steel, Ltd., Kobe-s...

1. A method for controlling the flow volume of coal/kerosene slurry in a solid-liquid separation process of supplying dehydrated coal/kerosene slurry to a decanter-type centrifugal separator and separating the coal/kerosene slurry into a solid fraction and a liquid fraction, comprising:deciding an opening degree target value on the basis of the difference between a torque target value and a value of a torque acting on a screw conveyer of the decanter-type centrifugal separator measured by a torque detection sensor;
adjusting the opening degree of a flow control valve to the opening degree target value, wherein the flow control valve is arranged in the middle of a supply line for supplying the coal/kerosene slurry into the decanter-type centrifugal separator;
driving the decanter-type centrifugal separator; and
adjusting the torque target value on the basis of the rotary torque detected by the torque detection sensor.

US Pat. No. 10,112,109

SHARED MULTIMEDIA EXPERIENCE INCLUDING USER INPUT

1. A multimedia distribution method comprising:providing multimedia content to a plurality of network clients via a multimedia network;
accessing user profiles corresponding to at least some of the network clients;
identifying, from collaboration group information included in at least some of the user profiles, a plurality of collaboration groups, including a first collaboration group and a second collaboration group, and a plurality of members of each of the collaboration groups;
sending a question pertaining to the multimedia content to each of the collaboration groups;
receiving responses to the question, wherein each of the responses includes a timestamp indicative of when the response was generated and a proposed answer to the question wherein the responses include a first response from the first collaboration group and a second response from the second collaboration group wherein the first response includes a first proposed answer to the question and the second response includes a second proposed answer to the question;
modifying the multimedia content provided to the first collaboration group to include the second proposed answer and modifying the multimedia content provided to the second collaboration group to include the proposed answer;
evaluating the first proposed and the second proposed answer to the question; and
determining, based on the timestamps and the evaluating of the first proposed answer and the second proposed answer, a winning response for each of the collaboration groups.

US Pat. No. 10,112,106

GAMING KIT FOR USE WITH ROLLING TARGET TOSSING GAME

1. A gaming kit for use by at least two players for playing a tossing and rolling game on a gaming surface, the gaming kit comprising:a. at least one target zone marker configured to be placed on the gaming surface, wherein each of the at least one target zone markers is further configured to identify a target zone area on the gaming surface;
b. one rolling piece comprising at least six side face surfaces, wherein each of the at least one rolling pieces is configured to be rolled across the gaming surface toward the target zone markers and come to rest at a resting point on the gaming surface relative to one of the at least one target zone markers; and
c. at least one tossing piece configured to be tossed toward one of the rolling pieces on the gaming surface, wherein each of the at least one tossing piece is configured to land at one of a plurality of landing positions relative to the at least one rolling piece,
wherein at least a portion of the side face surfaces of each of the at least one rolling pieces comprises a recessed portion configured to act as a compartment for receiving the at least one tossing piece.

US Pat. No. 10,112,096

HOCKEY TRAINING DEVICE

Steven Taylor, Toronto, ...

1. A hockey training device comprising:a connector assembly adapted to engage a blade of a hockey stick; and
a puck holding assembly;
a hinge provided between the connector assembly and the puck holding assembly; wherein the hinge permits the puck holding assembly and the connector assembly to pivot relative to each other.

US Pat. No. 10,112,095

SPORTS TRAINING DEVICE

Mr. Assist LLC, Westwood...

1. A sports training device, comprising:a circular main housing having opposed top and bottom surfaces each having a plurality of bosses formed thereon,
a channel formed within an intermediate housing section of the main housing and extending therethrough,
a fastening mechanism seated within the channel and secured to the main housing by a fastener, wherein the fastener mechanism includes a first fastener part and a separate and independent second fastener part, wherein the first fastener part and the second fastener part can be coupled together, and
a cord element having a first end portion mounted between the first fastener part and the second fastener part and being mechanically retained therebetween, wherein the cord element extends outwardly from the channel,
wherein the first fastener part comprises a main body having
a first end that includes a first skirt portion and an opposed second end that has a second skirt portion that forms a lip portion, wherein the lip portion projects in a direction opposite to a projection direction of first skirt portion, and
one or more cut-out portion that forms an outwardly projecting tab, and
wherein the second fastener part comprises a main body having
a first end that includes a first skirt portion and an opposed second end that has a skirt portion that forms a lip, wherein the lip portion projects in a direction opposite to a projection direction of the first skirt portion, and
one or more cut-out portions that form a pair of outwardly projecting tabs that are axially spaced apart along the main body.

US Pat. No. 10,112,088

GOLF FLAG MARKER

1. An attachment for a golf flag stick comprising:a hub constructed of a flexible resilient material, said hub having a central opening dimensioned to receive and resiliently grip the golf flag, said hub having a first slot communicating with the central opening,
a plurality of spokes, each spoke having an inner end attached to said hub, said spokes extending substantially radially outwardly from said hub and engaging, at outer ends, to a ring constructed of a flexible resilient material and surrounding said hub, a second slot in said ring communicating an exterior of said ring with said hub,
a subset pair of said plurality of spokes located on opposite sides of each of said first and second slots; and
separating said subset pair of spokes causing flexing of both said hub and ring for facilitating passage of the golf stick between the exterior of said ring and the central opening of said hub and/or for reposition-ably adjusting said hub at locations along the flag stick.

US Pat. No. 10,112,086

ASCENDING WEIGHT IRON SHAFT SYSTEM

Karsten Manufacturing Cor...

1. A plurality of starting stocks for manufacturing shafts of a system of golf clubs, comprising:a plurality of first starting stocks having a first average outer diameter, a first average inner diameter, a first average cross-sectional area, and first average weight-to-length ratio;
a plurality of second starting stocks having a second average outer diameter, a second average inner diameter, a second average cross-sectional area, and a second average weight-to-length ratio, wherein the second average weight-to-length ratio is greater than the first average weight-to-length ratio;
wherein one of the plurality of first starting stocks is configured to be cut to a first length, resulting in a first shaft having a first weight, the first shaft being assembled to a first club head with a first loft angle to make a first golf club in a particular stiffness class;
wherein one of the plurality of second starting stocks is configured to be cut to a second length, resulting in a second shaft having a second weight, the second shaft being assembled to a second club head with a second loft angle to make a second golf club in the same stiffness class as the first golf club, wherein the second weight is greater than the first weight, the second length is less than the first length, and the second loft is greater than the first loft;
wherein one of the plurality of first starting stocks is configured to be cut to a third length, resulting in a third shaft having a third weight, the third shaft being assembled to a third club head with a third loft angle to make a third golf club in a smaller stiffness class than the first golf club, wherein the third weight is less than the first weight, the third length is less than the first length and the third loft is greater than the first loft;
wherein one of the plurality of second starting stocks is configured to be cut to a fourth length, resulting in a fourth shaft having a fourth weight, the fourth shaft being assembled to a fourth club head with a fourth loft angle to make a fourth golf club in a smaller stiffness class than the second golf club, wherein the fourth weight is less than the second weight, the fourth length is less than the second length and the fourth loft is greater than the first loft;
wherein one of the plurality of first starting stocks is configured to be cut to a fifth length, resulting in a fifth shaft having a fifth weight, the fifth shaft may be assembled to a fifth club head with a fifth loft angle to make a fifth golf club in a greater stiffness class than the first golf club, wherein the fifth weight is greater than the first weight, the fifth length is greater than the first length and the fifth loft is less than the first loft;
wherein one of the plurality of second starting stocks is configured to be cut to a sixth length, resulting in a sixth shaft having a sixth weight, the sixth shaft may be assembled to a sixth club head with a sixth loft angle to make a sixth golf club in a greater stiffness class than the second golf club, wherein the sixth weight is greater than the second weight, the sixth length is greater than the second length, and the sixth loft is less than the first loft.

US Pat. No. 10,112,079

FLIPPERS, BOOTS, SYSTEMS INCLUDING SAME, AND METHODS OF USING SAME

Cetatek Holdings Inc., B...

1. A method of coupling a boot body to a fin apparatus comprising a fin body coupled to a foot coupling portion, the method comprising:connecting a first boot connector on the foot coupling portion to a first complementary boot connector on a top side of the boot body; and
connecting a second boot connector on the foot coupling portion to a second complementary boot connector on a bottom side of the boot body;
wherein connecting the second boot connector to the second complementary boot connector comprises positioning a holding surface of the second boot connector against a retaining surface on the bottom side of the boot body; and
wherein the retaining surface on the bottom side of the boot body is positioned to retain the second boot connector against movement in a direction towards the fin body when the holding surface of the second boot connector is positioned against the retaining surface on the bottom side of the boot body.

US Pat. No. 10,112,078

STEP ASSEMBLY WITH FALL ARREST CAPABILITY INCLUDING REMOVABLE STEP

VAF Industries, LLC, Esc...

1. A step assembly with fall arrest capability for use for climbing a utility structure, the step assembly comprising:a step unit comprising:
a rod having a flat surface along a longitudinal direction for placing a foot thereon for climbing,
two leg members transversally coupled to the rod, and
a loop section attached to the rod, on a side opposite to the flat surface, wherein two end portions of the loop section are attached at different points of the rod, thereby providing a generally D-shaped opening defined by the loop section and part of the rod between the two end portions of the loop section;
a leg holder comprising:
a center plate having a circular opening, and
two cylinders formed along two side edges of the center plate, respectively, wherein the two cylinders are configured for the two leg members to be inserted therethrough, respectively; and
an expansion anchor comprising:
a fin unit comprising a plurality of fins cylindrically disposed, each fin having a generally rectangle portion and a shoulder section formed contiguous to the rectangle portion, the shoulder section having a transversal dimension smaller than that of the generally rectangle portion;
wherein a combination of the leg holder and the expansion anchor is configured by inserting the expansion anchor through the circular opening of the center plate of the leg holder to have the plurality of fins on one side of the center plate, and the combination is configured to be secured with the utility structure based on bending the plurality of fins at the shoulder sections to have the plurality of fins opened inside the utility structure while the leg holder is in contact with and outside the utility structure, and
wherein the step unit is detachably attached to the secured combination by inserting the two leg members through the two cylinders of the leg holder, respectively.

US Pat. No. 10,112,070

BALANCE TRAINING DEVICE FOR YOUNG CHILDREN

I Shyang Enterprise Co., ...

1. A balance training device for young children comprising:a footplate mounted with at least one assembly hole formed on a bottom surface thereof, a recess portion is formed on a bottom surface of the footplate; a plurality of longitudinal ribs and a plurality of transverse ribs are disposed on the recess portion at intervals; the assembly hole is arranged at an intersection area of one longitudinal rib and one transverse rib;
at least one support disposed under the footplate and having an assembly pin projecting from a top end thereof;
a fixing block set on each of two sides of the assembly pin on the top end of the support, each fixing block being disposed with a mounting groove for mounting and fixing a transverse rib located on each of two sides of the assembly hole on the bottom surface of the footplate; and
at least one base arranged under the support and disposed with a positioning slot on a top end thereof;
wherein the assembly pin is able to be connected to the assembly hole of the footplate; a bottom end of the support is mounted in the positioning slot of the base; and the support and the positioning slot of the base are connected in a clearance fit.

US Pat. No. 10,112,066

OCCUPATIONAL THERAPY DEVICE

AJL LLC, Byron Center, M...

1. A mirror therapy device comprising:a mirror having a reflective surface;
a first functional component movably disposed on a first side of said mirror, said reflective surface providing a reflected image of said first functional component;
a second functional component movably disposed on a second side of said mirror, said second functional component being hidden by said mirror; and
a linkage operatively joining said first functional component to said second functional component, said linkage configured to cause said second functional component to move in a manner substantially consistent with said reflected image of said first functional component.

US Pat. No. 10,112,063

EMERGENCY ESCAPE SLIDE INCORPORATED INTO EXIT

AltEvac, LLC, Boca Raton...

1. An emergency escape mechanism for a building having a floor, comprising:an exit door located within a doorway on an exterior of the building, said doorway having an exterior side on the exterior of the building, and also having an interior side;
an inflatable emergency escape slide having a portion of a first end coupled to a lower portion of the doorway and a second end resting against an outer surface of the interior side of said exit door, said second end configured to drop out of said doorway when said exit door is opened;
an alarm box located proximate said exit door, said alarm box further including an alarm switch and wherein said alarm switch is further connected to a locking bar engaging said exit door;
an inertially-activated switch positioned on said first end;
a gas release device in gas communication with said inflatable emergency escape slide;
a girt bar anchored in the floor of the building in the lower portion of the interior side of the doorway; and
escape slide support straps attached to said girt bar and to said portion of said first end of said emergency escape slide, said alarm switch being coupled to said locking bar and being configured to be activated to cause said locking bar to cause said exit door to open, whereupon said first and second ends of said emergency escape slide go into motion as said second end automatically drops out of said doorway to a position outside the building, said inertially-activated switch automatically operating in response to said motion to generate an electrical signal, said gas release device being responsive to said electrical signal provided by said inertially-activated switch to inflate said emergency escape slide in automatic response to said electrical signal.

US Pat. No. 10,112,056

OPTIMISING CURRENT DIRECTION AND INTENSITY OF TRANSCRANIAL MAGNETIC STIMULATION

Monash University, (AU)

1. A method of optimising transcranial magnetic stimulation comprising:positioning a coil having a coil centre at a location relative to a target cortical region of a patient, wherein the target cortical region is a region outside of the motor cortex;
applying an electrical signal to the coil to generate one or more magnetic field pulses for transcranial magnetic stimulation of the target cortical region of the patient, wherein the transcranial magnetic stimulation has stimulation parameters including orientation of the coil relative to the patient and intensity of the magnetic stimulation;
while maintaining the coil centre at the location, varying at least the orientation of the coil relative to the patient;
at different orientations of the coil relative to the patient, monitoring neuron activation at the target cortical region using near infra-red spectroscopy (NIRS); and
based on information obtained during the monitoring, determining one or more optimal coil orientations for the transcranial magnetic stimulation.

US Pat. No. 10,112,051

METHODS, DEVICES, AND SYSTEMS FOR COMMUNICATING WITH AN IMPLANTABLE MEDICAL DEVICE OF A LAST FAR FIELD COMMUNICATION SESSION DURING A SUBSEQUENT FAR FIELD COMMUNICATION SESSION WHILE USING A SAME SESSION KEY

MEDTRONIC, INC., Minneap...

1. A method of communicating with an implantable medical device, comprising:sending a first key over a first proximity communication;
sending a first far field communication from an external device in an attempt to begin a first far field communication session with the implantable medical device and exchange communications during the first far field communication session with the implantable medical device where the external device expects the implantable medical device to use the first key when exchanging the communications during the first far field communication session;
conducting the first far field communication session with the implantable medical device when a response to the first far field communication is received by the external device that uses the first key;
terminating the first far field communication session;
sending a second key over a second proximity communication after terminating the first communication session;
after sending the second key, sending at least one far field communication by the external device in an attempt to begin a second far field communication session where the external device expects communications of the second session, including a response to the first far field communication, to use the second key;
conducting the second far field communication session using the second key when a response to the at least one far field communication of the second far field communication session is received by the external device that uses the second key; and
conducting the second far field communication session using the first key when a response to the at least one far field communication of the second far field communication session is received by the external device that uses the first key.

US Pat. No. 10,112,036

ENDOVASCULAR CEREBROSPINAL FLUID SHUNT

Tufts Medical Center, Inc...

1. A method for draining cerebrospinal fluid from a patient's subarachnoid space, the method comprising the steps of:providing an implantable shunt having opposed first and second ends, a one-way valve located at the first end of the shunt, and a tip disposed at the second end, said tip being constructed to penetrate a sinus wall of the patient, wherein the first and second ends are in fluid communication to enable the cerebrospinal fluid (CSF) to be drained through the tip and out through the valve;
endovascularly delivering the shunt to the sinus wall;
penetrating the sinus wall and implanting the second end of the shunt in a CSF space of the patient; and
draining cerebrospinal fluid from the patient.

US Pat. No. 10,112,032

MEDICAL TIMING DEVICE AND METHOD HAVING SINGLE ACTION TRIGGERING FOR ACTIVATION AND LOCK CONDITIONS

Harris Skeele Corporation...

1. A medical timing device comprising:a body comprising a first lock member, wherein the body defines an article-receiving space configured to receive an article portion of a medical article;
a timer coupled to the body, wherein the timer is configured to indicate an in-use time of the medical article;
a triggering element; and
a retainer coupled to the triggering element, the retainer being moveably coupled to the body, wherein the retainer is configured to be moved from an open position providing access to the article-receiving space to a closed position blocking at least part of the article-receiving space, wherein the retainer comprises a second lock member;
wherein the retainer is configured so that, in response to a single action of moving the retainer from the open position to the closed position, the triggering element:
activates the timer to initiate a process to indicate the in-use time of the medical article; and
causes the second lock member to become locked together with the first lock member to lock the retainer in the closed position after the article portion has been inserted in the article-receiving space,
wherein the locked retainer is configured to keep the medical timing device coupled to the article portion even after the timer indicates that the medical article has been used for more than a designated usage period,
wherein the locked retainer is configured to prevent the medical timing device from being removed from the article portion without use of a tool or partial destruction of the article portion or the medical timing device, thereby inhibiting wrongful removal of the medical timing device from the article portion.

US Pat. No. 10,112,030

INTRODUCER SHEATH ASSEMBLY HAVING A LOCKING DILATOR

1. A method of releasing an introducer sheath assembly having a longitudinal axis defining an axial direction along the longitudinal axis, a transverse direction transverse to the longitudinal axis, and a rotational direction about the longitudinal axis, the introducer sheath assembly including a valve, an introducer sheath secured at an end of the valve, an introducer tool coaxially received in the introducer sheath, and a fitting secured to the introducer sheath, the method comprising:unlocking a locking mechanism of the introducer sheath assembly, including rotating a lock knob of the locking mechanism in the rotational direction to unlock the locking mechanism without causing movement of the introducer tool in the axial direction and without causing movement of the introducer tool in the rotational direction, wherein unlocking the lock knob does not disturb fluid sealing engagement between the introducer tool and the valve or cause rotation of the introducer tool relative to the introducer sheath during unlocking of the locking mechanism, and wherein unlocking the locking mechanism includes releasing the lock knob from the fitting by rotating the lock knob; and
sliding the introducer tool from the introducer sheath in the axial direction after unlocking the locking mechanism, wherein the fitting includes an axially extending groove and wherein the lock knob includes an axially projecting lock tab and the fitting includes an annular slot receiving the lock tab to secure the lock knob to the fitting prior to unlocking the locking mechanism, and wherein the lock knob is configured to translate through the axially extending groove as the locking mechanism is axially separated from the fitting.

US Pat. No. 10,112,029

BONE CONDUCTION APPARATUS AND MULTI-SENSORY BRAIN INTEGRATION METHOD

INTEGRATED LISTENING SYST...

1. A method for the enhancement of sensory processing and sensory integration of a subject within a setting including a plurality of subjects, comprising:evaluating the subject to determine one or more deficiencies within one or more developmental phases;
developing a therapeutic regimen to remedy the determined deficiencies;
filtering a composition, comprising music and sounds, to change the relative amplitude of a frequency range within the composition and generating two output signals;
delivering said filtered composition to the plurality of subjects through air conduction audio room speakers based on a first output signal of the two output signals;
transmitting wirelessly, to combination air conduction/bone conduction headphones of the subject, a second output signal derived from said filtered composition; and
directing said subject to perform one or more activities from one or more groups of activities associated with said frequency range, each activity directed toward the one or more determined deficiencies,
wherein an amplitude of the first output signal and the second output signal are independently variable, and
wherein the combination air conduction/bone conduction headphones include controls such that an amplitude of the second output signal driving the air conduction portion of the headphones and the second output signal driving the bone conduction portion of the headphones are independently variable.

US Pat. No. 10,112,028

HUMIDIFICATION CHAMBER FOR A RESPIRATORY ASSISTANCE APPARATUS

1. A humidification chamber for humidifying gases, comprising:a water tub that is configured to receive a volume of water;
a lid hingedly coupled to the water tub for enclosing the water tub to define the interior volume of the humidification chamber and which is movable between a closed position in which the water tub is closed by the lid and an open position in which the water tub is open,
wherein a seal is located between the lid and the water tub, the seal engaging a perimeter of the water tub;
wherein the lid is formed from plastic, and
wherein the water tub comprises a base, a perimeter wall that extends upwardly from the base, and a metallic heater plate, an underside of the base comprising a rigid plastic portion and an exposed metallic portion of the metallic heater plate;
one or more clips for securing the lid in the closed position;
a lateral gases inlet for receiving a flow of gases into the interior volume of the humidification chamber, wherein the gases inlet is formed in the lid, the gases inlet having an associated inlet conduit extending into the interior volume of the humidification chamber; and
a lateral gases outlet through which a humidified flow of gases may exit the interior volume of the humidification chamber, wherein the gases outlet is formed in the lid, the gases outlet having an associated outlet conduit extending into the interior volume of the humidification chamber.

US Pat. No. 10,112,024

MEDICAL TUBE APPARATUS

Monitoring For Life LLC, ...

1. An endotracheal tube apparatus having a proximal end and a distal end, and further comprising:an endotracheal tube having a proximal end and a distal end;
a hub connection fitting connected to the endotracheal tube, the hub connection fitting disposed adjacent the proximal end of the endotracheal tube proximal to the proximal end of the endotracheal tube;
the endotracheal tube configured to be inserted into a trachea of a human body;
a ventilation passageway disposed in the hub connection fitting and along a length of the endotracheal tube;
a cuff inflation passageway disposed in the hub connection fitting and the endotracheal tube;
a light emitting device comprising a light source and a tubular light guide, the light source and the tubular light guide arranged such that light, when emitted from the light source, is transmitted along a longitudinal axis of the tubular light guide;
the light source disposed in the hub connection fitting; and
the tubular light guide disposed in the endotracheal tube within the cuff inflation passageway.

US Pat. No. 10,112,014

SYRINGE ASSEMBLY HAVING A FLEXIBLE OR A SLIDABLE FLANGE

Becton Dickinson France, ...

1. A syringe assembly comprising:a syringe barrel having a proximal end and a distal end, said distal end including an outlet portion; and
a slidable flange positioned about the syringe barrel, said slidable flange comprising:
a slidable flange member having a first end and a second end; and
an aperture extending through said slidable flange member; and
a locking member provided at the proximal end of the syringe barrel for locking the slidable flange member with respect to the syringe barrel,
wherein a first diameter of the aperture extending along a minor axis of the aperture is smaller than a second diameter of the aperture extending along a major axis of the aperture, the minor axis being coplanar with and perpendicular to the major axis, and
wherein the slidable flange is transitionable from a first pre-use position to a second use position and in the pre-use position, the entirety of the flange member is angled with respect to a longitudinal axis of the syringe barrel such that the first end of the flange member is farther from the distal end of the syringe barrel than the second end of the flange member and, in the second use position, the first end of the flange member and the second end of the flange member are equidistant from the distal end of the syringe barrel and the flange member creates the flange extending in a perpendicular direction with respect to the longitudinal axis of the syringe barrel.

US Pat. No. 10,112,008

MEDICAL DEVICE FOR ADMINISTERING A SOLUTION

DEBIOTECH S.A., Lausanne...

1. A medical device for administering a solution, said device comprising:a pump that is not inside a patient,
a reservoir that is not inside the patient, and
a communication structure for connecting said reservoir and said pump, wherein said communication structure is not inside the patient, and
a line for connecting the medical device to the patient,
a sensor for measuring an exposure of the solution, which is contained in the reservoir, to temperature, to humidity, or to pressure of the solution, or ageing or permeability of the reservoir, over the course of time,
wherein the medical device uses a mathematical model in order to determine at any moment physical or chemical characteristics of the solution, which is contained in the reservoir, wherein the mathematical model takes account of a modification of the solution in the reservoir over the course of time as a function of an exposure to temperature, to humidity, or to pressure of the solution, or ageing or permeability of the reservoir; and
wherein the medical device informs the patient about refilling the solution or changing the reservoir depending on the modification of the characteristics of the solution.

US Pat. No. 10,112,002

SYSTEM FOR BLOOD SEPARATION WITH REPLACEMENT FLUID APPARATUS AND METHOD

Terumo BCT, Inc., Lakewo...

1. A disposable blood processing set for use on a centrifugal blood processing device, said disposable set comprising:a blood separation chamber adapted to be mounted on a rotor of said centrifugal blood processing device;
a blood inlet line adapted to be coupled to a blood donor and to an inlet pump on said centrifugal blood processing device;
an anti-coagulant line in fluid communication with said inlet line, said anti-coagulant line being adapted to be fluidly coupled to a supply of anti-coagulant and being further adapted to be coupled to an anti-coagulant pump on said centrifugal blood processing device;
a reservoir adapted to be coupled to at least one sensor for detecting a level of fluid in said reservoir;
a return line in fluid communication with said reservoir, said return line being adapted to be coupled to said blood donor and to a return pump on said centrifugal blood processing device;
a red blood cell line in fluid communication with said blood separation chamber and said reservoir;
a collect line in fluid communication with said blood separation chamber and in selective communication with said reservoir and a collect bag, said collect line being adapted to be coupled to a collect pump;
a plasma line in fluid communication with said blood separation chamber and with said reservoir, said plasma line being adapted to be coupled to a plasma pump; and
a replacement fluid line in fluid communication with said reservoir and adapted to be placed in fluid communication with a source of replacement fluid.

US Pat. No. 10,111,886

POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT

POLYACTIVA PTY LTD, Melb...

1. A polymer-bioactive agent conjugate, comprising a moiety of formula (I):
where:
T represents a triazole moiety;
Q is independently selected at each occurrence and may be present or absent and when present represents a linking group;
R is an optionally substituted aromatic hydrocarbon or heteroaromatic hydrocarbon;
Z is a cleavable linking group; and
D is a releasable bioactive agent selected from prostaglandin analogues.

US Pat. No. 10,111,882

SYK INHIBITORS

GILEAD SCIENCES, INC., F...

1. A method of treating or reducing aplastic anemia in a patient in need thereof, comprising administering to the patient an effective amount of a compound selected from:or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,111,878

N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER

Agios Pharmaceuticals, In...

1. A method of treating acute myelogenous leukemia characterized by the presence of an IDH2 mutation, comprising the step of administering to the patient a therapeutically effective amount of a compound having Formula II:or a pharmaceutically acceptable salt thereof, wherein:ring A? is selected from phenyl, pyrimidin-2-yl, pyrimidin-4-yl, pyrimidin-5-yl, oxazol-4-yl, isoxazol-3-yl, thiazol-2-yl, pyridin-3-yl and pyridin-2-yl, wherein ring A? is optionally substituted with one or two substituents independently selected from 1-propenyl, -cyclopropyl-OH, chloro, fluoro, —CF3, —CHF2, —CH3, —CH2CH3, —CF2CH3, —S(O)CH3, —S(O)2CH3, —CH2OH, —CH(OH)CH3, —CH(OH)CF3, —OH, —OCH3, —OCF3, —OCH2CH3, —C(O)—NH2, —CH2NH2, —NH2, —NH(CH3), —CN and —N(CH3)2; and
ring B? is selected from phenyl, pyridin-3-yl, pyridin-4-yl, pyridazin-4-yl, isoxazol-4-yl, isoxazol-3-yl, thiazol-5-yl, pyrimidin-5-yl and pyrazol-4-yl, wherein ring B? is optionally substituted with one to two substituents independently selected from halo; —CN; —OH; C1-C4 alkyl optionally substituted with halo, CN or —OH; —S(O)2—C1-C4 alkyl; —S(O)—C1-C4 alkyl; —S(O)2—NH—C1-C4 alkyl; —S(O)2—NH—CH2—CF3; —S(O)2—N(C1-C4 alkyl)2; —S(O)2-azetidin-1-yl; —O—C1-C4 alkyl; —CH2—O—CH3, morpholin-4-yl, cyclopropyl, cyclopropyl-C1-C4 alkyl, cyclopropyl-C1-C4 alkoxy, cyclopropyl-CN, —S(O)2—NH-cyclopropyl; —S(O)2—NH—CH2-cyclopropyl; —C(O)—C1-C4 alkyl, —C(O)—O—CH3; wherein:
a. ring A? and ring B? are not both an optionally substituted phenyl;
b. when ring A? is unsubstituted pyridyl, then ring B? is not phenyl optionally substituted with one to three groups independently selected from methyl, ethyl, t-butyl, methoxy, CH(OH)CH3, Cl, Br, and CF3;
c. when ring A? is oxazol-4-yl, isoxazol-3-yl, or thiazol-2-yl, then ring B? is not phenyl optionally substituted with one to two groups independently selected from F, Cl, SO2CH3, C(O)OCH3, methyl, ethyl, t-butyl, methoxy, ethoxy, CF3, and OH;
d. the compound is not:
(2) 6-(6-methoxy-3-pyridinyl)-N2-(4-methylphenyl)-1,3,5-triazine-2,4-diamine;
(3) 6-(2-methoxy-3-pyridinyl)-N2-(4-methylphenyl)-1,3,5-triazine-2,4-diamine.

US Pat. No. 10,111,858

PHARMACEUTICAL FOR PROPHYLAXIS OR TREATMENT OF HYPERTENSION

Daiichi Sankyo Company, L...

1. A method for the treatment of diabetic nephropathy, comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical comprising(i) a mineralocorticoid receptor antagonist represented by formula (I):

an atropisomer thereof, or a pharmacologically acceptable salt thereof, and
(ii) (5-methyl-2-oxo-1,3-dioxolan-4-yl) methyl-4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2?-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]imidazole-5-carboxylate, or a pharmacologically acceptable salt thereof.

US Pat. No. 10,111,841

STABILIZATION OF ALCOHOL INTOXICATION-INDUCED CARDIOVASCULAR INSTABILITY

UNIVERSITY OF SOUTH FLORI...

1. A method for stabilizing blood pressure in a subject having alcohol-induced hypotension, comprising intravenously administering an effective amount of fingolimod, or a pharmaceutically acceptable salt thereof, to the subject, wherein said administering ameliorates the alcohol-induced hypotension.

US Pat. No. 10,111,820

COMPOSITION FOR HAIR FRIZZ REDUCTION

The Procter and Gamble Co...

1. A rinse-off conditioner composition for hair frizz reduction comprising:from about 0.2% to about 20.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following:

wherein R is hydrogen or metal ion, R6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R7, R8, R9, R10, R11, and R12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups;

an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and
wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms;
c) alcohol comprising an unsaturated double bond in the C2 position;
d) an alkyl-substituted glycol wherein the structure of such alkyl substituted glycol contains less than 20 carbon atoms;
e) a monoalkyl or dialkyl substituted glycerin or mono- or di-esters of glycerin with fatty acids, wherein the structure of such monoalkyl- or di-alkyl-substituted glycerin or glycerin esters contains less than 20 total carbon atoms;

wherein R15 could be hydrogen, alkyl, alkenyl, phenyl group and wherein the structure of the R15 group contain less than 20 carbon atoms; or
g) a fatty acid ester containing from 15-40 total carbon atoms;
and wherein the moisture control material is weakly to non-acidic and further wherein the moisture control material has protein binding higher than 10, a log P higher than 0.5, a pKa of 5 or higher and a hydrogen-binding higher than 4 and wherein the rinse-off conditioner composition exhibits at least about a 4% frizz reduction versus control composition without the moisture control materials wherein the rinse-off conditioner composition comprises at least one moisture control material selected from group consisting of 2-hexyl-1-decanol, isostearyl isostearate or mixtures thereof and further comprising from about 0.5% to about 2% of salicylic acid, chlorosalicylic acid or mixtures thereof, and from about 2% to about 10% of 2-hydroxyethyl urea.

US Pat. No. 10,111,818

USE OF CHARGED SURFACTANTS FOR REDUCING TEXTILE STAINING BY ANTIPERSPIRANTS

BEIERSDORF AG, Hamburg (...

1. A cosmetic or dermatological preparation, wherein the preparation comprises (i) one or more antiperspirant substances and (ii) one or more surfactants comprising one or more cationic surfactants of formula (I), a weight ratio (i):(ii) being from 1:1 to 30:1wherein:R1 represents a saturated or unsaturated linear alkyl group having from 8 to 24 carbon atoms,
R2 represents a saturated linear alkylene group having from 1 to 10 carbon atoms and being substituted with from 0 to 5 hydroxy groups,
R3, R4, R5 independently of one another represent hydrogen, a C1-C4 alkyl group, a C5 or C6 cycloalkyl group, or a C2-C4 hydroxyalkyl group, and
X represents a monovalent anion.

US Pat. No. 10,111,810

THIN FILM WITH NON-SELF-AGGREGATING UNIFORM HETEROGENEITY AND DRUG DELIVERY SYSTEMS MADE THEREFROM

Aquestive Therapeutics, I...

1. A process for manufacturing a continuously cast oral film for delivery of an active in individual self-supporting oral unit doses cut therefrom, said individual self-supporting oral unit doses containing a desired amount of said active, comprising the steps of:(a) forming a Non-Newtonian visco-elastic polymer matrix by mixing, said matrix comprising a polymer selected from the group consisting of water-soluble polymers, water-swellable polymers and combinations thereof, a solvent selected from the group consisting of—water, ethanol, isopropanol, acetone, methylene chloride, and a combination thereof and said active, which polymer matrix is a shear-thinning pseudoplastic fluid when exposed to shear rates of 10-105 sec?1, said polymer matrix having a substantially uniform distribution of said pharmaceutical active;
(b) continuously casting said polymer matrix;
(c) removing at least a portion of said solvent from said matrix to achieve a solvent content of no greater than 10% by weight of said continuously cast oral film;
wherein said continuously cast oral film has a substantially uniform distribution of said active substantially locked-in within said polymer matrix, wherein said active is selected from the group consisting of cosmetic agents, pharmaceutical agents, vitamins, bioactive agents and combinations thereof wherein said active is substantially uniformly distributed in said continuously cast film, whereby said substantially uniform distribution is measured by substantially equally sized individual self-supporting oral unit doses cut from said continuously cast film which do not vary by more than 10% of said desired amount of said active and
wherein said pharmaceutical active is an anti-parkinsonian agent.

US Pat. No. 10,111,795

SHOWER FALL PREVENTION DEVICE

1. A shower fall prevention device suitable for fixing on a ceiling of a shower, comprising:an extendable and retractable belt rolled up in a box in a retracted state and configured to fix the device to the ceiling of the shower at a fixing point; and
two arm pit hooks configured to receive arms of a user and pivotably connected to the fixing point.