US Pat. No. 10,337,105

METHOD AND APPARATUS FOR VALVE DEPOSITION CLEANING AND PREVENTION BY PLASMA DISCHARGE

MKS Instruments, Inc., A...

1. A valve assembly comprising:a vacuum valve including an electrically grounded surface;
an electrode adjacent to the electrically grounded surface of the vacuum valve;
a barrier dielectric, at least a portion of which is located between the electrode and the electrically grounded surface; and
a dielectric barrier discharge structure formed from the electrically grounded surface, the electrode, and the barrier dielectric, wherein the dielectric barrier discharge structure is adapted to generate a plasma in a gap between the barrier dielectric and the electrically grounded surface to process at least a portion of the vacuum valve, and wherein the electrically grounded surface of the vacuum valve forms a grounded electrode for generating the plasma.

US Pat. No. 10,337,104

ZIRCONIUM, HAFNIUM, TITANIUM PRECURSORS AND DEPOSITION OF GROUP 4 CONTAINING FILMS USING THE SAME

1. A Group 4 transition metal-containing film forming composition comprising a Group 4 transition metal precursor of formula:L2-M-C4AR3-3-[(ER2)m-(ER2)n-L?]-,
referring to the following structure:

wherein M is Zr bonded in an ?5 or ?6 bonding mode to the five-membered aromatic group; each A is independently N, Si, B or P;
each E is independently C, Si, B or P; m and n is independently 0, 1 or 2; m+n>1;
each R is independently H or a C1-C4 hydrocarbon group; each L is independently selected from the group consisting of NR?2, OR?, Cp, amidinate, ?-diketonate, and keto-iminate, wherein R? is a H or a C1-C4 hydrocarbon group and adjacent R?s may be joined to form a hydrocarbyl ring; and L? is NR? or O, wherein R? is H or a C1-C4 hydrocarbon group.

US Pat. No. 10,337,101

SYSTEM AND PROCESS FOR CHEMICAL VAPOR DEPOSITION

THE BOEING COMPANY, Chic...

1. A method comprising:flowing a carrier liquid through a reactor;
introducing a fluid comprising one or more reactants into the carrier liquid, the fluid being at a first temperature and first pressure and being sufficiently immiscible in the carrier liquid so as to form a plurality of microreactors suspended in the carrier liquid, each of the microreactors comprising a discrete volume of the fluid surrounded by the carrier liquid and having a surface boundary defined by an interface of the fluid with the carrier liquid;
heating and optionally pressurizing the fluid to a second temperature and second pressure at which a chemical vapor deposition reaction occurs within the microreactors to form a plurality of chemical vapor deposition products, the surface boundary acting as a substrate for the chemical vapor deposition reaction; and
separating the plurality of chemical vapor deposition products from the carrier liquid.

US Pat. No. 10,337,098

METHOD FOR GROWING CARBON NANOTUBES

Tsinghua University, Bei...

1. A method of growing carbon nanotubes, the method comprising:constructing a reactor, wherein the reactor comprises a reactor chamber and a carbon nanotube catalyst composite layer suspended in the reactor chamber, and the carbon nanotube catalyst composite layer comprises a carbon nanotube layer and a plurality of catalyst particles dispersed in the carbon nanotube layer;
introducing a mixture of carbon source gas and carrier gas into the reactor chamber to penetrate the carbon nanotube catalyst composite layer, wherein a flow direction of the mixture of carbon source gas and the carrier gas is perpendicular to a surface of the carbon nanotube catalyst composite layer; and
heating the carbon nanotube catalyst composite layer.

US Pat. No. 10,337,092

STEEL SHEET

1. A steel sheet, whereina chemical composition comprises, by mass %:
C: more than 0.25% and 0.48% or less;
Si: 0.10% to 0.60%;
Mn: 0.40% to 0.90%;
Al: 0.003% to 0.070%;
Ca: 0.0005% to 0.0040%;
REM: 0.0003% to 0.0050%;
Cu: 0% to 0.05%;
Nb: 0% to 0.05%;
V: 0% to 0.05%;
Mo: 0% to 0.05%;
Ni: 0% to 0.05%;
Cr: 0% to 0.50%;
B: 0% to 0.0050%;
P: limited to 0.020% or less;
S: limited to 0.0070% or less;
Ti: limited to 0.050% or less;
O: limited to 0.0040% or less;
N: limited to 0.0075% or less; and
remainder including iron and impurity,
amounts of each elements by mass % in the chemical composition satisfy both of expression 1 and expression 2,
a number density of carbonitrides including Ti which exists independently and has a long side of 5 ?m or more is limited to 5 pieces/mm2 or less,
0.3000?{Ca/40.88+(REM/140)/2}/(S/32.07):  expression 1, and
Ca?0.0058?0.0050×C:  expression 2,
a number density of A-type inclusions, which is defined as inclusions of which an aspect ratio is 3.0 or more, is 6 pieces/mm2 or less,
a total number density of B-type inclusions, which are defined as inclusions which form inclusion groups in which three or more of the inclusions form a line along the working direction, in which clearance between the inclusions is 50 ?m or less, and in which the aspect ratio of the inclusions are less than 3.0, and C-type inclusions, which are defined as inclusions of which an aspect ratio is 3.0 or less, and which disperse in a random manner, is 6 pieces/mm2 or less, and
a number density of coarse inclusions, which is defined as inclusions which are B-type or C-type and of which maximum length are 20 ?m or more, is 6 pieces/mm2 or less.

US Pat. No. 10,337,089

PROCESS FOR PRODUCING A COMPONENT MADE OF HEAT-TREATED CAST IRON

Ford Global Technologies,...

1. A process comprising:casting an engine block main body from a cast iron;
boring the main body to form a bore having a first shape;
heat treating the main body having the bore to establish an ausferritic microstructure of the main body and the bore having a second shape; and
machining the bore having the second shape after the heat treating step.

US Pat. No. 10,337,082

HEARTH ROLL AND CONTINUOUS ANNEALING FACILITY

JFE STEEL CORPORATION, T...

1. A hearth roll for supporting and conveying a steel sheet in a furnace of a continuous annealing facility having a heating zone, a soaking zone and a cooling zone, wherein the hearth roll comprises a shaft portion made of a ceramic material as a rotation center of the roll and a roll main body made of a ceramic material formed on the circumference of the shaft portion and having an outer peripheral surface in contact with the steel sheet,wherein the hearth roll is constituted with concentric ceramic layers made from different ceramic materials centering on a rotation axis of the roll, and a ratio of thermal expansion coefficient of the ceramic material in an inner layer to the ceramic material in an outer layer within an operating temperature range is in a range of 0.5-1.5.

US Pat. No. 10,337,076

PNEUMATIC ORE CHARGING

PRIMETALS TECHNOLOGIES AU...

1. A method for reducing metal oxide containing charge materials, comprising:reducing the metal oxide containing charge materials with a reduction gas in at least a first and a second fluidized bed units, and flowing the reduction gas through the fluidized bed units countercurrently to the metal oxide containing charge materials;
removing as off-gas from the first fluidized bed unit the reduction gas used during reduction of the metal oxide containing charge materials in the at least two fluidized bed units;
compressing at least some of the off-gas in at least one recycle gas compressor to produce hot recycle gas, and then cooling the hot recycle gas in at least one aftercooler to produce cold recycle gas;
at least partially removing CO2 from the cold recycle gas to produce product gas;
admixing the product gas with the reduction gas;
optionally, after pre-heating in a heating device, conveying the metal oxide containing charge materials by a propellant gas from at least one delivery tank by a pipe line into the first fluidized bed unit;
wherein the propellant gas comprises at least some of the hot recycle gas;
the hot recycle gas has a lower temperature limit of 70° C. and an upper temperature limit of 150° C.;
the product gas has a dew point of below ?20° C.; and
the pressure of the hot recycle gas is at least 4.5 bars.

US Pat. No. 10,337,059

ENTHALPY MEASUREMENTS FOR SEQUENCING OF A NUCLEIC ACID SAMPLE

The Board of Trustees of ...

1. A method for sequencing a nucleic acid sample, comprising:(a) providing a plurality of nucleic acid molecules and a polymerase in one or more thermally isolated chambers among a plurality of thermally isolated chambers that each has a volume of less than 0.1 ?L, wherein each of said plurality of nucleic acid molecules comprises (i) a nucleic acid sequence of a single-stranded nucleic acid template derived from said nucleic acid sample, and (ii) a primer hybridized thereto, which primer comprises a hairpin formed by self-hybridization of said single-stranded nucleic acid template or a single-stranded oligonucleotide that has sequence complementarity with said single-stranded nucleic acid template;
(b) providing a plurality of nucleotides of a single species in said one or more thermally isolated chambers comprising said plurality of nucleic acid molecules;
(c) detecting an enthalpy change in said one or more thermally isolated chambers comprising said plurality of nucleic acid molecules, wherein said enthalpy change is associated with incorporation of one or more nucleotides of said plurality of nucleotides of said single species by said polymerase into a nucleic acid strand growing from said primer, wherein said nucleic acid strand has sequence complementarity with said single-stranded nucleic acid template; and
(d) repeating (b) and (c) to obtain a sequence of said single-stranded nucleic acid template.

US Pat. No. 10,337,057

METHODS AND SYSTEMS FOR NUCLEIC ACID SEQUENCING VALIDATION, CALIBRATION AND NORMALIZATION

LIFE TECHNOLOGIES CORPORA...

1. A system for performing quality control for nucleic acid sample sequencing, the system comprising:a set of solid supports, each solid support having attached thereto one or more nucleic acid sequences comprising a plurality of nucleic acid molecules,
wherein the set comprises plural groups of solid supports and each group contains solid supports having same ones of the one or more nucleic acid sequences attached thereto,
wherein the plural groups of solid supports are divided into a plurality of subsets,
wherein the one or more nucleic acid sequences are attached such that, when nucleic acid sample sequencing is performed, all possible color transitions are observed for consecutive ligation cycles for each subset of the plural groups of solid supports,
wherein the one or more nucleic acid sequences of each group differ from the one or more nucleic acid sequences each other groups,
wherein the one or more nucleic acid sequences are synthetically derived, and
wherein the one or more nucleic acid sequences produce a predefined pattern of detectable signals during a sequencing run.

US Pat. No. 10,337,054

ENRICHMENT OF NUCLEIC ACID TARGETS

Quantum-Si Incorporated, ...

1. A method for isolating a second molecule from a first molecule in a sample, the method comprising: applying a time-varying driving field to the sample in the presence of an affinity matrix comprising immobilized probes, the probes having a first binding affinity for the first molecule that is greater than a second binding affinity for the second molecule; applying a periodically varying, mobility-altering field that modifies the first and second binding affinities; wherein application of the time-varying driving field and the periodically varying, mobility-altering field concentrates the second molecule within the affinity matrix and separate from the first molecule;wherein the sample further comprises a background molecule with a third binding affinity that is less than the first and second binding affinities and wherein application of the time-varying driving field and periodically varying mobility-altering field concentrates the second molecule within the affinity matrix and separate from the first molecule and the background molecule.

US Pat. No. 10,337,047

ASSAY FOR EARLY DETECTION OF A DISEASE USING A MAGNETIC NANOPARTICLE BIOSENSOR

Alfaisal University, Riy...

1. A method to detect two periodontal marker enzymes in combination to diagnose a periodontal disease, comprising:conjugating of a Human Neutrophil Elastase (HNE) and a Cathepsin-G substrate peptide and their substrate sequences Seq ID No. 3 and Seq ID No. 4 to magnetic beads to make a magnetic nanoparticle biosensor;
preparing more than one self-assembled monolayer of peptide coupled carboxy terminated magnetic bead on a gold sheet to form a gold sensor support, wherein a top monolayer comprises a Cathepsin-G peptide complex and a bottom monolayer comprises a HNE peptide complex;
fitting a round permanent magnet on back of the gold sensor support;
reacting the gold sensor support by applying the biological sample which contains a protease to cleave the Cathepsin-G enzyme and HNE enzyme in a specific concentration; andmeasuring the association or dissociation of the peptide coupled carboxy terminated magnetic bead on the gold sensor support to detect presence and intensity or absence of the periodontal disease in a human.

US Pat. No. 10,337,039

PROCESS FOR THE PREPARATION OF CHIRAL 2-ARYL MORPHOLINES

Hoffmann-La Roche Inc., ...

1. A process for the preparation of a chiral 2-(4-aminophenyl) morpholine of formula (I)wherein R1 is hydrogen or an amino protecting group (PG) said process comprising the steps of:(a) reducing a ketone of the formula II wherein X is a halogen atom with an

ketoreductase enzyme to afford the chiral alcohol of the formula IIIa;
(b) displacing the halogen intramolecularly followed by in situ ring opening

of the resulting epoxide IIIb with ethanolamine to afford IVb;
(c) introducing a protecting group to afford IVa wherein PG is an amino protecting group;
(d) contacting IVa with R3SO2X wherein X is a halogen to afford VI;

(e) cyclizing VI to afford the chiral morpholine V wherein PG is as defined

above;
(f) reducing the nitro group to afford chiral 2-(4-aminophenyl) morpholine of the formula I wherein R1 is an amino PG; and,
(g) optionally removing the amino protecting group PG to afford a compound of formula I wherein R1 is a H.

US Pat. No. 10,337,035

METHOD FOR PREPARING ORGANIC ACID BY FED-BATCH-FEEDING CARBON SOURCE SUBSTRATE AND BASE

SK INNOVATION CO., LTD., ...

1. A method for producing an organic acid by fed-batch culture, comprising:(i) preparing a culture medium containing a carbon source substrate, an organic acid-producing strain of bacteria, and a growth ingredient for said strain of bacteria;
(ii) fermenting said culture medium to produce said organic acid;
(iii) measuring a pH change in said culture medium;
(iv) correlating said pH change to consumption of said carbon source substrate;
(v) fed-batch feeding additional substrate-base mixture of carbon source substrate and an alkali metal containing weak base to said culture medium in an amount to maintain concentration of said carbon source substrate, and said alkali metal containing weak base in an amount to matain optimal pH for growth of said strain of bacteria, and
(vi) removing any organic acid produced in said culture medium;
wherein ratio of carbon source substrate to alkali metal containing weak base is 200˜300 g/L to 80˜120 g/L,
wherein CO2 and H2 gases are generated during said fermenting, and when CO2 and H2 gases reach a generation rate of 1.5-2.5 L/L of fermenter/hr, terminating the feeding the substrate-base mixture so that said fermenting proceeds until said carbon source substrate is completely consumed.

US Pat. No. 10,336,997

CONTINUOUS DIRECTED EVOLUTION

President and Fellows of ...

1. An apparatus for continuous evolution of a gene of interest, the apparatus comprising(a) a lagoon comprising
a cell culture vessel comprising a population of M13 phages comprising a gene of interest to be evolved and lacking a functional pIII gene required for the generation of infectious phage particles, and a population of bacterial host cells, wherein
(1) the M13 phages allow for expression of the gene of interest in the host cells,
(2) the host cells are suitable host cells for M13 phage infection, replication, and packaging, wherein the M13 phage comprises all phage genes required for the generation of phage particles, except a functional pIII gene;
(3) the host cells comprise an expression construct encoding the pIII protein, wherein expression of the pIII gene is dependent on a function of a gene product of the gene of interest;
(4) the host cells comprise an expression construct encoding a dominant-negative pIII protein (pIII-neg), wherein the pIII-neg protein is driven by a promoter the activity of which depends on an undesired function of a gene product encoded by the gene of interest;
an inflow connected to a turbidostat;
an outflow;
a controller controlling inflow and outflow rates; and,
(b) a turbidostat comprising
a cell culture vessel comprising a population of fresh host cells;
an outflow connected to the inflow of the lagoon;
an inflow connected to a vessel comprising liquid media
a turbidity meter measuring the turbidity of the culture of fresh host cells in the turbidostat; and,
a controller controlling the inflow of sterile liquid media and the outflow into the waste vessel based on the turbidity of the culture liquid.

US Pat. No. 10,336,996

DEVICE AND METHOD FOR LARGE VOLUME TRANSFECTION

LONZA COLOGNE GMBH, Colo...

1. Device for applying an electric field to a suspension of cells, cell derivatives, organelles, sub-cellular particles and/or vesicles, comprising:at least one chamber which has a curved shape and comprises
at least two electrodes, and
at least one separating element which is movable within the chamber between two terminal points and, if the at least one separating element is in a position between the terminal points, separates at least one first compartment of the chamber from at least one second compartment of the chamber, wherein each compartment is adapted to hold the suspension and comprises at least one port for charging or discharging the suspension, and wherein the separating element is operatively coupled to an adjusting element, said adjusting element being a rotatable body.

US Pat. No. 10,336,987

LIVER TISSUE CULTURING DEVICE, LIVER TISSUE CULTURING SYSTEM, LIVER TISSUE CULTURING METHOD, AND LIVER FUNCTION EVALUATION METHOD

SHIMADZU CORPORATION, Ky...

1. A method for culturing a liver tissue comprising: seeding at least an endothelial cell, a hepatocyte, and a mesenchymal cell on a gel which serves as a cell scaffold material; and co-culturing the cells to culture a co-culture system which contains at least the endothelial cell, the hepatocyte, and the mesenchymal cell,wherein the mesenchymal cell is a stellate cell or a fibroblast,
and wherein the system has a tubular structure.

US Pat. No. 10,336,977

BIOREACTOR FOR CELL CO-CULTURE

CONSEJO SUPERIOR DE INVES...

1. A bioreactor for cell co-culture, comprising:a base;
a cover;
a membrane between the base and the cover; and
at least first and second cell culture chambers, said first chamber being provided between the membrane and the cover and the second membrane being provided between the membrane and the base,
wherein said bioreactor can be disassembled by separating said base from said cover,
wherein said membrane includes at least a first sealing gasket integrated with said membrane, and is porous for cell seeding and culturing,
wherein said first sealing gasket is made of an elastomeric material and defines a closed perimeter delimiting an area of said membrane which is a first cell seed and culture area,
wherein said first chamber includes at least one perfusion fluid inlet duct discharging a perfusion fluid into a first flow manifold and at least one outlet duct extending from a second flow manifold,
wherein said first and second flow manifolds are provided at opposite ends of said first chamber and configured to discharge over said membrane the perfusion fluid across an entire width of said first chamber such that, in an assembled state of the bioreactor, a space is defined between the first cell seed and culture area of said membrane and a bottom of said first chamber, and
wherein at least the bottom of said first chamber is dimensioned to cause a laminar flow of said perfusion fluid, said laminar flow having a homogenous velocity over a whole of said first cell seed and culture area.

US Pat. No. 10,336,965

PROCESS FOR THE EXTRACTION OF LIPIDS AND SUGARS FROM ALGAL BIOMASS

ENI S.p.A., Rome (IT)

1. A process for extracting lipids and sugars from algal biomass, the process comprising:adjusting the pH of an aqueous suspension of algal biomass to a value of 10.2 to 12 by adding at least one hydroxide of an alkaline metal, or at least one hydroxide of an alkaline-earth metal, or a mixture thereof; or as the algae consumes carbon dioxide (CO2) during the growth of the algal biomass, thereby obtaining an aqueous suspension of algal biomass at a basic pH;
adding at least one anionic flocculant to said aqueous suspension of algal biomass at the basic pH, thereby obtaining a concentrated algal biomass;
recovering said concentrated algal biomass leaving a clarified aqueous phase;
subjecting said concentrated algal biomass to lipid extraction, thereby obtaining:
(i) an organic phase comprising lipids; and
(ii) a semi-solid phase comprising a residue of said algal biomass;
subjecting said semi-solid phase (ii) to hydrolysis, thereby obtaining the sugars; and
recycling the clarified aqueous phase to cultivation of algae without further treatment.

US Pat. No. 10,336,962

COMPOSITION FOR SOLID LUBRICATING COATING, THREADED CONNECTION FOR PIPE OR TUBE INCLUDING THE SOLID LUBRICATING COATING FORMED FROM THE COMPOSITION, AND METHOD OF PRODUCING THE THREADED CONNECTION

VALLOUREC OIL AND GAS FRA...

1. A composition for forming a solid lubricating coating on a threaded connection for pipe or tube, by comprising:a binder,
a fluorine addition agent
a solid lubricant, and
a rust proof addition agent;
characterized in that:the binder comprises:an ethylene-vinyl acetate resin,
a polyolefin resin, and
a wax having a fusing point of 110° C. or less;a ratio of a mass of the ethylene-vinyl acetate resin to a mass of the polyolefin resin is from 1.0 to 1.8; anda ratio of a total mass of the polyolefin resin and the ethylene-vinyl acetate resin to a mass of the wax is from 0.7 to 1.6.

US Pat. No. 10,336,954

COMPOSITIONS AND METHODS FOR INHIBITING FOULING IN HYDROCARBONS OR PETROCHEMICALS

BL TECHNOLOGIES, INC., M...

1. An antifoulant composition for inhibiting fouling on structural parts of a system exposed to a fluid hydrocarbon or petrochemical stream, said antifoulant composition comprising (1) at least one polyalkylene anhydride ester (“PAAE”) dispersant, wherein said dispersant is a polyisobutenyl succinic anhydride derived ester (“PASAE”) with a molecular weight, Mw, of about 1,000 to about 25,000, wherein said polyisobutenyl succinic anhydride ester (“PASAE”) includes a polyol moiety, wherein said polyol moiety is represented by the formulawherein R is a polyisobutenyl moiety, said dispersant providing a stable dispersion when mixed with said fluid hydrocarbon or petrochemical stream, wherein said fluid hydrocarbon or petrochemical stream comprises heavy crudes or crude blends,wherein said at least one structural part is selected from the group consisting of hydrocarbon or petroleum storage units, heat exchangers, piping, pumps, flow meters, valves, desalters, preheat furnaces, furnaces, coker preheaters, cokers, distillation columns, fractionation columns, atmospheric columns, pipe stills, debutanizers, reactors, fluid catalytic cracking units, fluid catalytic cracking slurry settlers, hydrocracking units, steam cracking units, thermal cracking units, visbreakers, reflux units, condensers, and scrubbers.

US Pat. No. 10,336,952

MIXING DEVICE FOR A DOWN-FLOW HYDROPROCESSING REACTOR

Chevron U.S.A. Inc., San...

1. A mixing device for a multi-bed down-flow catalytic reactor, the mixing device comprising:a. a top plate having an inner surface and a periphery;
b. a base plate extending parallel to the top plate, the base plate having an inner surface, a periphery, and a base plate aperture, wherein the top and base plates are separated by a distance to define an interior region of the mixing device;
c. a plurality of inwardly-directed vanes contained within the interior region of the mixing device extending perpendicular to and interposed between the inner surfaces of the top and base plates, wherein the vanes are inwardly-directed from the periphery of the top and base plates toward the base plate aperture and are spaced around the area extending from the base plate aperture to the periphery of the top and base plates; and
d. a mixing region;
wherein, the mixing device does not include a weir ring extending from the inner surface of the base plate or a bubble cap extending from the inner surface of the top plate.

US Pat. No. 10,336,946

CATALYTIC PYROLYSIS METHOD AND APPARATUS

1. A process comprising:passing to a feed mixture through a line reactor, the mixture comprising 100 parts by weight heavy oil (API<22.3), from about 5 to 100 parts by weight water, and from about 1 to 20 parts by weight solid catalyst particulates comprising a mineral support and an oxide or acid addition salt of a Group 3-16 metal;
heating the feed mixture in the reactor at a temperature, pressure, and for a period of time sufficient to produce a pyrolyzate vapor phase at an exit from the reactor condensable to form an oil phase lighter than the heavy oil, wherein the mixture comprises an emulsion of the oil, water, and catalyst particulates.

US Pat. No. 10,336,944

DIRECT SYNTHESIS OF HYDROCARBONS FROM CO-ELECTROLYSIS SOLID OXIDE CELL

University of South Carol...

1. A hydrocarbon generation system comprising:a plurality of microtubular reactors in an array, each microtubular reactor including
a first region including a cathode and an anode in electrical communication with one another and an oxygen ion conducting electrolyte between the cathode and the anode,
a second region including a Fischer-Tropsch reaction catalyst in fluid communication and downstream of the cathode; and
a temperature control unit configured to provide the first region at a first temperature that is greater than a second temperature of the second region, wherein each microtubular reactor defines a continuous space, such that the first region and second region are in contact producing a temperature gradient along each microtubular reactor.

US Pat. No. 10,336,937

MONOLITHIC RARE EARTH OXIDE AEROGELS

Lawrence Livermore Nation...

1. A method for making a monolithic rare earth oxide (REO) aerogel, comprising:preparing a reaction mixture consisting essentially of at least one rare earth metal nitrate, at least one epoxide, at least one base catalyst, and at least one organic solvent, wherein the reaction mixture is substantially free of chloride;
curing the mixture to produce a wet gel;
drying the wet gel to produce a dry gel; and
thermally annealing the dry gel to produce the monolithic REO aerogel.

US Pat. No. 10,336,921

ADHESIVE COMPOSITIONS FOR NONWOVEN APPLICATIONS

ExxonMobil Chemical Paten...

1. An adhesive composition comprising:(a) a polymer blend comprising
a first propylene-based polymer, wherein the first propylene-based polymer is a homopolymer of propylene or a copolymer of propylene and ethylene or a C4 to C10 alpha-olefin; and
a second propylene-based polymer, wherein the second propylene-based polymer is a homopolymer of propylene or a copolymer of propylene and ethylene or a C4 to C10 alpha-olefin, wherein the second propylene-based polymer is different than the first propylene-based polymer,
wherein the polymer blend has a melt viscosity, measured at 190° C. of about 3,000 cP to about 12,000 cP; and
(b) one or more tackifiers;
wherein the one or more tackifiers has a softening point as determined by ASTM E-28 of about 80° C. to about 145° C., an aromaticity of about 3 mol % to about 11 mol % aromatic protons, and a Cloud Point of about ?10 ° C. to about 15 ° C.,
wherein the polymer blend is present in the amount of about 50 wt % to about 90 wt % of the adhesive composition.

US Pat. No. 10,336,902

HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS

SABIC GLOBAL TECHNOLOGIES...

1. An article comprising a thermoplastic composition comprising:(a) 45 to 70 wt % of a first polycarbonate that includes structural units derived from at least one of:
wherein Ra and Rb at each occurrence are each independently halogen, C1-C12 alkyl, C1-C12 alkenyl, C3-C8 cycloalkyl, or C1-C12 alkoxy; p and q at each occurrence are each independently 0 to 4; R13 at each occurrence is independently a halogen or a C1-C6 alkyl group; c at each occurrence is independently 0 to 4; R14 at each occurrence is independently a C1-C6 alkyl, phenyl, or phenyl substituted with up to five halogens or C1-C6, alkyl groups; Rg at each occurrence is independently C1-C12 alkyl or halogen, or two Rg groups together with the carbon atoms to which they are attached form a four-, five, or six-membered cycloalkyl group; and t is 1 to 10;(b) 15 to 30 wt % of a poly(aliphatic ester)-polycarbonate copolymer of the formula:

wherein m is 4 to 18; x, and y each represents parts by weight of the carbonate units and the ester units based on 100 parts total weight of the poly(aliphatic ester)-polycarbonate copolymer, x+y is 100; and R3 is formula (I) or formula (II):

wherein Rh is halogen, alkyl, or haloalkyl; n is 0 to 4; and Xa is formula (III) or formula (IV):

wherein Rc and Rd are each independently hydrogen, halogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl; and Re is a divalent alkyl group; and
(c) optionally a second polycarbonate that is a Bisphenol A polycarbonate having a weight average molecular weight of 17,000 to 40,000 g/mol, as determined by gel permeation chromatography using Bisphenol A polycarbonate standards;
wherein the thermoplastic composition further comprises 0.05 to 10 wt % of a flame retardant and 5 to 35 wt % of glass fiber, provided that the combined wt % value of all components does not exceed 100 wt %,
the composition has a heat deflection temperature of at least 120° C., measured at 1.8 MPa in accordance with ASTM D 648; and
a melt viscosity of less than 130 Pa·s, measured in accordance with ISO 11443 at 316° C. at a shear rate of 5000 s?1, and
a molded sample of the composition obtained under standard molding conditions has a notched izod impact energy of at least 20 Jim at 23° C., as measured in accordance with ASTM D 256.

US Pat. No. 10,336,896

ONE-POT SYNTHESIS OF HIGHLY MECHANICAL AND RECOVERABLE DOUBLE-NETWORK HYDROGELS

The University of Akron, ...

1. A method of forming a hybrid physically and chemically cross-linked double-network hydrogel with highly recoverable and mechanical properties in a single-pot synthesis comprising the steps of:combining the hydrogel precursor reactants including:
a. water,
b. a polysaccharide,
c. an acrylate monomer,
d. an ultraviolet initiator, and
e. a chemical crosslinker to form a single pot mixture;
heating the hydrogel precursor reactants to a temperature higher than the melting point of the polysaccharide and retaining this temperature until the polysaccharide is in a sol state;
cooling the single-pot to a temperature lower than the gelation point of the polysaccharide and retaining this temperature to form a first network; and
thereafter photo-initiating polymerization of the acrylate monomer via the ultraviolet initiator to form the second network, wherein the double-network hydrogel has a polysaccharide concentration of 20 mg/mL, an acrylate monomer concentration of 3.4 mol/L, a ultraviolet initiator concentration of 1 mol % of acrylate monomer, and a chemical crosslinker concentration of 0.03 mol % of acrylate monomer.

US Pat. No. 10,336,891

METHODS AND COMPOSITIONS RELATED TO RECYCLING POLYMER WASTE

ImerTech SAS, Paris (FR)...

1. A functional filler comprising:an inorganic particulate material, wherein the inorganic particulate material has a d50 of less than about 10 ?m; and
a coating comprising a first compound including a terminating propanoic group or ethylenic group with one or two adjacent carbonyl groups,
wherein the first compound has the following formula:
A-(X—Y—CO)m(O—B—CO)nOH
wherein:
A is a moiety containing a terminating ethylenic bond with one or two adjacent carbonyl groups;
X is O and m is 1 to 4 or X is N and m is 1;
Y is C1-18-alkylene or C2-18-alkenylene;
B is C2-6-alkylene;
n is 0 to 5;
provided that when A contains two carbonyl groups adjacent to the ethylenic group, X is N.

US Pat. No. 10,336,889

PNEUMATIC TIRE

1. A pneumatic tire having a tread comprising a vulcanizable rubber composition comprising, based on 100 parts by weight of elastomer (phr),100 phr of a diene based elastomer having a glass transition temperature less than ?50° C., wherein the diene based elastomer is selected form the group consisting of natural rubber, polybutadiene, synthetic polyisoprene, solution polymerized styrene-butadiene rubber with bound styrene content ranging from 9 to 15 percent by weight, and emulsion polymerized styrene-butadiene rubber with bound styrene content ranging from 5 to 23.5 percent by weight;
from 40 to 55 phr of a fatty acid monoester of formula 1
where R1 is selected from C1 to C8 linear or branched alkyl, and C1 to C8 linear or branched alkenyl; R2 is C11 to C21 alkyl or C11 to C21 alkenyl;less than 10 phr of a processing oil;
from 50 to 130 phr of silica; and
optionally, from about 5 to 50 phr carbon black.

US Pat. No. 10,336,875

HALOGEN-FREE RESIN COMPOSITION AND PREPREG AND LAMINATE PREPARED THEREFROM

SHENGYI TECHNOLOGY CO., L...

18. A laminate comprising the prepreg of claim 16.

US Pat. No. 10,336,868

POLYCARBOXYLATED COMPOUNDS AND COMPOSITIONS CONTAINING SAME

WISCONSIN ALUMNI RESEARCH...

1. A polycarboxylated compound comprising phenylpropanoid units, wherein:each phenylpropanoid unit comprises an ?-carbon and a ?-carbon;
the phenylpropanoid units are linked to each other via linkages selected from the group consisting of a ?-O-4 linkage, a ?-1 linkage, a ?-5 linkage, a 4-O-5 linkage, a 5-5 linkage, and a ?-? linkage;
the phenylpropanoid units comprise ?-O-4 phenylpropanoid units;
each of the ?-O-4 phenylpropanoid units is a single one of the phenylpropanoid units and is linked via its ?-carbon with a ?-O-4 linkage;
each ?-O-4 phenylpropanoid unit in at least a portion of the ?-O-4 phenylpropanoid units comprises a secondary hydroxyl moiety on the ?-carbon of the ?-O-4 phenylpropanoid unit and a carboxylic acid or carboxylate moiety on the ?-carbon of the ?-O-4 phenylpropanoid unit; and
the polycarboxylated compound further comprises a phenylpropanoid unit linked via a ?-1 linkage, a phenylpropanoid unit linked via a 4-O-5 linkage, or a phenylpropanoid unit linked via a ?-1 linkage and a phenylpropanoid unit linked via a 4-O-5 linkage.

US Pat. No. 10,336,864

PRODUCTION METHOD FOR POLY(AMINO ACID)

TAKEDA PHARMACEUTICAL COM...

1. An ionized graft copolymer represented by Formula (II):
suitable for production of nanoparticles, wherein M is alkali metal, A is a hydrophobic moiety, and n is an integer from 10 to 100,000; diagonal lines intervening three monomer units represent that the monomer units are arranged in irregular order, and x is a mole fraction of the monomer unit represented by Formula (III):

y is a mole fraction of the monomer unit represented by Formula (IV):

z is a mole fraction of the monomer unit represented by Formula (V):
andx, y, and z satisfy the following equations:
0?x<1;
0 0 x+y+z=1.

US Pat. No. 10,336,851

COPOLYMER FOR SEMICONDUCTOR LITHOGRAPHY, RESIST COMPOSITION, AND METHOD FOR MANUFACTURING SUBSTRATE

Mitsubishi Chemical Corpo...

1. A copolymer for lithography having a turbidity Th(80) of 1.0 NTU or more and 4.6 NTU or less and a turbidity Tm(80) of 1.0 NTU or more and 3.8 NTU or less, whereinthe turbidity Th(80) is a turbidity of a PGMEA solution when n-heptane in an amount to be 80% of (X)h is added to the PGMEA solution where (X)h denotes an amount of n-heptane added to have a turbidity of 10 NTU when n-heptane is added to the PGMEA solution containing the copolymer for lithography at 20 wt % with respect to a total mass of the PGMEA solution; and
the turbidity Tm(80) is a turbidity of a PGMEA solution when methanol in an amount to be 80% of (X)m is added to the PGMEA solution where (X)m denotes an amount of methanol added to have a turbidity of 5.0 NTU when methanol is added to the PGMEA solution containing the copolymer for lithography at 20 wt % with respect to a total mass of the PGMEA solution.

US Pat. No. 10,336,842

TRANSITION METAL COMPOUND AND CATALYST COMPOSITION INCLUDING THE SAME

LG CHEM, LTD., Seoul (KR...

1. A transition metal compound of the following Chemical Formula 1:
wherein,
M is a group 4 transition metal;
R is selected from the group consisting of an alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, an arylalkyl group having 7 to 20 carbon atoms, and an alkylaryl group having 7 to 20 carbon atoms;
R1 and R2 are each independently selected from the group consisting of a hydrogen atom, an alkyl group having 1 to 20 carbon atoms, an alkenyl group having 2 to 20 carbon atoms, a haloalkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, an arylalkyl group having 7 to 20 carbon atoms, an alkylaryl group having 7 to 20 carbon atoms, and combinations thereof, or R1 and R2 are linked to each other to form an aliphatic ring having 3 to 20 carbon atoms or an aromatic ring having 6 to 20 carbon atoms;
R3 to R8 are each independently selected from the group consisting of a hydrogen atom, a halogen group, an alkyl group having 1 to 20 carbon atoms, an alkenyl group having 2 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, an arylalkyl group having 7 to 20 carbon atoms, an alkylaryl group having 7 to 20 carbon atoms, an alkoxy group having 1 to 20 carbon atoms, an aryloxy group having 6 to 20 carbon atoms, a silyl group, and combinations thereof, or adjacent two or more functional groups among R3 to R8 are linked to each other to form an aliphatic ring having 3 to 20 carbon atoms or an aromatic ring having 6 to 20 carbon atoms;
R9 is selected from the group consisting of an alkyl group having 1 to 20 carbon atoms, an alkenyl group having 2 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, an arylalkyl group having 7 to 20 carbon atoms, an alkylaryl group having 7 to 20 carbon atoms, a silyl group, and a metalloid radical of a group 14 metal substituted with a hydrocarbyl group having 1 to 20 carbon atoms;
X1 and X2 are each independently selected from the group consisting of a halogen group, an alkyl group having 1 to 20 carbon atoms, an alkenyl group having 2 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, an alkylaryl group having 7 to 20 carbon atoms, an arylalkyl group having 7 to 20 carbon atoms, an alkylamino group having 1 to 20 carbon atoms, an arylamino group having 6 to 20 carbon atoms, and an alkylidene group having 1 to 20 carbon atoms;
R, R1 to R9, X1 and X2 are each independently unsubstituted or substituted with one or more substituents selected from the group consisting of a halogen group, an alkyl group having 1 to 20 carbon atoms, a haloalkyl group having 1 to 20 carbon atoms, an alkenyl group having 2 to 20 carbon atoms, an alkoxy group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, an arylalkyl group having 7 to 20 carbon atoms, an alkylaryl group having 7 to 20 carbon atoms, and an aryloxy group having 6 to 20 carbon atoms; and
n is an integer of 1 or 2, and when n is an integer of 2, two R9s are the same as or different from each other.

US Pat. No. 10,336,841

SELF SUPPORTED PHOSPHINIMINE CATALYST

NOVA Chemicals (Internati...

1. A spherical self supported single site catalyst having a diameter from 5 to 200 ?m comprising a catalyst of the formula
wherein M is a transition metal selected from Ti, Hf and Zr; PI is a phosphinimine ligands of the formula:

wherein each R21 is independently selected from a hydrogen atom; a halogen atom; C1-20, hydrocarbyl radicals which are unsubstituted by or further substituted by a halogen atom; a C1-8 alkoxy radical; a C6-10 aryl or aryloxy radical; an amido radical; a silyl radical of the formula:
—Si—(R22)3
wherein each R22 is independently selected from hydrogen, a Ci-8 alkyl or alkoxy radical, and C6-10 aryl or aryloxy radicals; and a germanyl radical of the formula:
—Ge—(R22)3
wherein R22 is as defined above;
L is a monoanionic ligand selected from a cyclopentadienyl ligand which is substituted by up to three C1-6 linear, branched, cyclic or aromatic hydrocarbons which are unsubstituted or up to fully substituted by fluorine atoms; and
Y is independently selected from a halogen atom, C1-4 alkyl radicals, C6-20 aryl radicals, C7-12 arylalkyl radicals, C6-10 phenoxy radicals, amido radicals which is optionally substituted by up to two C1-4 alkyl radicals and C1-4 alkoxy radicals; m is 1 or 2; n is 0 or 1; p is an integer and the sum of m+n+p equals the valence state of M;
supported on an activator of the formula:
R122AlO(R12AlO)qAlR122
wherein each R12 is independently selected from C1-20 hydrocarbyl radicals and q is from 3 to 50 to provide a molar ratio of A1 from the activator to M from the catalyst from 5:1 to 90:1.

US Pat. No. 10,336,838

PROCESS FOR PRODUCING OLEFIN POLYMER AND OLEFIN POLYMER

MITSUI CHEMICALS, INC., ...

1. A 4-methyl-1-pentene polymer fulfilling the following requirements (a) to (c):(a) the amount of constituent units derived from 4-methyl-1-pentene is 100 to 80 mol %, and the amount of constituent units derived from at least one selected from olefins having 2 to 30 carbon atoms (except 4-methyl-1-pentene) is 0 to 20 mol %;
(b) the meso diad fraction (m) as measured by 13C-NMR is 98.5% to 100%; and
(c) the heat of fusion ?Hm (unit: J/g) and the melting point Tm (unit: ° C.) as measured by Differential Scanning calorimetry (DSC) fulfill the following relation (1):
?Hm?0.5×Tm?76.  Relation (1):

US Pat. No. 10,336,792

ANTIMICROBIAL PEPTIDE DENDRIMERS

UNIVERSITAT BERN, Bern (...

1. A method of antibacterial treatment, comprising administering to a subject in need thereof, a peptide dendrimer described by a general formulaX—(B2-[Y2]s-D1)2-B1Z, wherein
X is
(D2)4, or
(D3)8-(B3-[Y3]r-D2)4,and whereineach Y (Y2 and Y3) independently from any other Y is a linkage moiety di- or tripetide H-Cys or CH-Cys linked to the N-terminus of the C-terminally neighboring amino acid in D through a thioether moiety exemplified by the formula

wherein the sulfur atom belongs to the cysteine and the amino group constitutes the N-terminus of the neighboring amino acid in D, wherein the C-terminus of cysteine is a carboxamide,
r and s is 0 or 1;
Z is a central moiety;
each B (B1, B2, and B3) independently from any other B denotes a diaminoalkylcarboxylic acid moiety described by the general formula: CnH2n-1(NH2)2CO— wherein n is a number between 2 and 10,
each D (D1, D2, and D3) independently from any other D is
i) a dipeptide CH, HC, CC or HH, or
ii) a tripeptide HCH, HHC, CHH, CCH, CHC, HCC, HHH or CCC wherein
H is any amino acid comprising a hydrophobic side chain, and
C is any amino acid comprising a cationic side chain,
thereby providing antibacterial treatment to the subject.

US Pat. No. 10,336,785

METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS

Qiagen Sciences, LLC, Ge...

1. A compound wherein the structure is:

US Pat. No. 10,336,784

METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF

ACADEMIA SINICA, Taipei ...

1. A method of preparation of a compound having the general formula:
wherein, each of R2, R3, R4, R1?, R2?, and R3? is independently selected from —H, benzyl (Bn), acetyl (Ac), benzoyl (Bz), or independently selected from a sugar moiety selected from:

wherein at least one of R2, R3, R4, R1?, R2?, and R3? is one of said sugar moieties,
wherein, each of R5, R6, R7, R8, R9 R10, and R12 is independently selected from —H, benzyl (Bn), acetyl (Ac), or benzoyl (Bz);
R11 is selected from —H, Me (methyl) or Et (ethyl);
R13 is selected from —H, benzyl (Bn), acetyl (Ac), benzoyl (Bz), or:

X is —OR14 or an anomeric leaving group;
wherein, R14 is selected from H, alkyl, alkenyl, alkynyl, aryl, unsubstituted aryl, substituted aryl; benzyl (Bn), para-methoxy benzyl ether (PMB), methoxy phenyl ether (PMP), or allyl ether (allyl);
Y is —NHR16; and R16 is acetyl (Ac),
wherein the method comprises the stepwise enzymatic extension on a hydroxyl group of a compound having the structure of formula (III):

wherein,
each of R1? and R2? is independently selected from —H, acetyl (Ac), or benzoyl (Bz);
X? is —OR3? and R3? is selected from —H, benzyl (Bn), para-methoxy benzyl ether (PMB), methoxy phenyl ether (PMP), or allyl ether (allyl);
wherein the enzymes to enzymatically extend the compounds of formula (III) are independently selected from the group consisting of ? (1?2) Fucosyltransferase, ? (1?3) N-acetyl glucosamine transferase, and ? (2?3) sialyltransferase.

US Pat. No. 10,336,778

PRODRUGS OF GLUTAMINE ANALOGS

The Johns Hopkins Univers...

1. A compound selected from the group consisting of:

US Pat. No. 10,336,770

PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY

Curis, Inc., Lexington, ...

1. A compound represented by formula (II);or a pharmaceutically acceptable salt thereof,wherein represents a single or double bond;
X and Y are independently CR1, N(R8), S or O , wherein when one of X and Y is CR1, the other is N(R8), S or O;
R1 is selected from hydrogen, hydroxy, amino, halogen, alkoxy, alkylamino, dialkylamino, CF3, CN, NO2, sulfonyl, acyl, aliphatic, substituted aliphatic, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic;
G1 is O;
G2 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or, substituted or unsubstituted heterocyclic;
each R8 is independently hydrogen, acyl, aliphatic or substituted aliphatic;
B is a linker; and
C is

 wherein R33 is hydrogen.

US Pat. No. 10,336,756

(S)-2-(1-AMINOPROPYL)-5-FLUORO-3-PHENYLQUINAZOLIN-4(3H)-ONE PRECURSOR OF A QUINAZOLINONE AS INHIBITOR OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA

ICOS CORPORATION, Foster...

2. A composition, comprising a compound having a structure

US Pat. No. 10,336,750

COMPOSITION AND METHODS FOR THE TREATMENT OF CAMKK2-MEDIATED DISORDERS

Duke University, Durham,...

1. A method of modulating CaMKK2 in a subject comprising administering to the subject an effective amount of a compound comprising the Formula (I):
or a pharmaceutically acceptable salt, solvate, hydrate, or derivative thereof,
wherein R1 and R2 are Hydrogen (H), and R3 is selected from the group consisting of

US Pat. No. 10,336,749

METHOD FOR THE PREPARATION OF (4S)-4-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1-6-NAPHTHYRIDINE-3-CARBOXAMIDE AND THE PURIFICATION THEREOF FOR USE AS AN ACTIVE PHARMACEUTICAL INGREDIENT

BAYER PHARMA AKTIENGESELL...

1. A process for preparing a compound of the formula (I)
comprising separating a racemic compound of the formula (XIII) into its enantiomers, wherein the compound of the formula (XIII)

is prepared by reacting a compound of the formula (XVIII)

with an orthoester (XX)

where R may be H or methyl, wherein
the compound of the formula (XVIII)

is prepared by reacting compounds of the formula (XVI a,b)

with a compound of the formula (IX)

and wherein
the compound of the formula (XVI a,b) is prepared by reacting a compound of the formula (VI)

with a compound of the formula (XVII)

US Pat. No. 10,336,743

AMINOPYRIMIDINE KINASE INHIBITORS

Jasco Pharmaceuticals, LL...

1. A compound selected from the group consisting of:or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,336,738

COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM

CALCIMEDICA, INC., La Jo...

1. A compound having the structure of Formula (I):
wherein:
R1 is

X is S, O, or NRS;
Y is independently selected from CR10 or N;
R2 is aryl, heteroaryl, fused aryl or fused heteroaryl; wherein aryl, heteroaryl, fused aryl or fused heteroaryl is optionally substituted with at least one R3;
R3 is independently selected from the group consisting of H, F, D, Cl, Br, I, —CN, —NO2, —OH, —CF3, —OCF3, —OR5, optionally substituted C1-C6alkyl, optionally substituted C3-C8cycloalkyl, optionally substituted C1-C6heteroalkyl, C1-C6haloalkyl, optionally substituted C2-C8heterocycloalkyl, optionally substituted aryl, optionally substituted O-aryl, and optionally substituted heteroaryl;
R5 is selected from the group consisting of H, C1-C6alkyl, C1-C6haloalkyl, C3-C8cycloalkyl, phenyl, and benzyl; and
R9 and R10 are each independently selected from H, D, optionally substituted C1-C6alkyl, halogen, C1-C6 alkylcarbonyl, or CF3;
or a pharmaceutically acceptable salt, pharmaceutically acceptable solvate, or pharmaceutically acceptable prodrug thereof.

US Pat. No. 10,336,729

4-CYANO-BENZYL CARBAMIMIDOYLCARBAMATE DERIVATIVES AND THEIR USE AS AOC3 INHIBITORS

Boehringer Ingelheim Inte...

1. A compound of formula (I)
wherein
R1 is H or halogen;
R2 is H or halogen;
R3 is H or halogen;
with the proviso that not more than one of R1, R2 and R3 is halogen;
A is selected from the group consisting of:

R4 is selected from the group consisting of: pyrrolidinyl, piperidinyl, piperazinyl, tetrahydropyranyl, oxazolidinyl, C3-8-cycloalkyl, phenyl, pyridinyl, pyrazinyl, pyridazinyl, pyrimidinyl, [1,3,5]triazinyl, triazolyl, thiazolyl, imidazo[1,2-a]pyridin-2-yl, oxazolyl and oxadiazolyl,
wherein each R4 is optionally substituted with one or more groups independently of each other selected from the group consisting of halogen, OH, CO2H, CN, CF3, C1-3-alkyl, C1-3-alkyl-O—, (RN)2N—, C1-3-alkyl-C(?O)—, C1-4-alkyl-O—C(?O)—, (RN)2N—C(?O)—, (RN)2N—C1-3-alkyl-, C3-6-cycloalkyl-C1-3-alkyl-O—, C1-3-alkyl-SO2—, (RN)2N—SO2— and C1-3-alkyl-C(?O)—(RN)N—C1-3-alkyl-; and
wherein a —CH2— group of the pyrrolidinyl, oxazolidinyl, piperidinyl or piperazinyl group of R4 is optionally replaced with a —C(?O)— group;
RN is H or C1-4-alkyl;
R5 is CN or OH;
or, R4 and R5 groups together with the carbon atom, to which they are attached, may form the following group:
wherein each of the above-mentioned alkyl and —O-alkyl groups may be linear or branched and are optionally substituted by one or more F;or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,336,724

D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF

SyneuRx International (Ta...

1. A compound of Formula (I):
or a pharmaceutically acceptable salt thereof, wherein:
the moiety

the moiety

 is bonded to E;
X is aryl;
Y is a five-membered heteroaryl with 1-2 ring heteroatoms selected from the group consisting of nitrogen and oxygen;
Z is aryl;
L1 is CH2 or C2-10 alkyl;
L2 is CH2, C2-10 alkyl, —CH2S—, or absent;
provided that when L2 is present, L2 is bonded to B or C, and when L2 is absent, Z is aryl fused with BC.

US Pat. No. 10,336,712

COMPOUND FOR ENHANCING THE COUPLING DEGREE OF COMPLEX TRPV4-KCA2.3 AND ANTI-HYPERTENSION APPLICATIONS THEREOF

JIANGNAN UNIVERSITY, Wux...

1. A preparation method of a compound for enhancing the space coupling degree of an endothelial cell ion channel complex TRPV4-KCa2.3, wherein structural domains of interacting sites of the endothelial cell ion channel complex TRPV4-KCa2.3 are structural domain AR2 of protein TRPV4 and structural domain 17C of protein KCa2.3 and the compound is represented by structure formula (1):
the method comprising:
providing propane diamine with t-butyloxycarboryl to protect a single amino first:

an exposed amino reacting with diphenylacetyl chloride to generate an amide:

removing a t-butyloxycarboryl protection from the amide under an acidic condition:

a compound obtained after removing the t-butyloxycarboryl protection performing an amino-ester exchange with 4-quinazolone-2-carboxylic acid ethyl ester to obtain a target compound:

US Pat. No. 10,336,703

PROCESS FOR THE SYNTHESIS OF IVACAFTOR AND RELATED COMPOUNDS

Council of Scientific and...

1. A one pot process for the preparation of compounds of formula (I) and formula (II);wherein, Ar1 is a 5-6 membered aromatic/hetero aromatic ring, which could be further substituted by alkyl, aryl, hetero aryl and having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is optionally fused to a 5-12 membered monocyclic or bicyclic, aromatic, partially unsaturated, or saturated ring, wherein each ring contains 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein Ar1 has m substituents, each selected independently from —WRW; W is a bond or is an optionally substituted C1-C6 alkylidene chain wherein up to two methylene units of W are optionally and independently replaced by —CO—, —CS—, —COCO—, —CONR?—, —CONR?NR?—, —CO2—, —OCO—, —NR?CO2—, —O—, —NR?CONR?—, OCONR?, —NRTSIR?, —NR?NR?CO—, —NR?CO—, —S—, —SO, —SO2—, —NR?—, —SO2NR?—, NR?SO2—, or —NR?SO2NR?—; RW is independently R?, halo, NO2, CN, CF3, or OCF3; m is 0-5; each of R1, R2, R3, R4, and R5 is hydrogen, —X—RX; X is a bond or is an optionally substituted C1-C6 alkylidene chain wherein up to two methylene units of X are optionally and independently replaced by —CO—, —CS—, —COCO—, —CONR?—, —CONR?NR?—, —CO2—, —OCO—, —NR?CO2—, —O—, —NR?CONR?—, —OCONR?—, —NRTSIR?, —NR?NR?CO—, —NR?CO—, —S—, —SO, —SO2—, —NR?—, —SO2NR?—, NR?SO2—, or —NR?SO2NR?—; RX is independently R?, halo, NO2, CN, CF3, or OCF3; R6 is hydrogen, CF3, —OR?, —SR?, or an optionally substituted C1-6 aliphatic group; R7, R8 is hydrogen or a C1-6 aliphatic group optionally substituted with —X—RX; R? is independently selected from hydrogen or an optionally substituted group selected from a C1-C8 aliphatic group, a 3-8-membered saturated, partially unsaturated, or fully unsaturated monocyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or an 8-12 membered saturated, partially unsaturated, or fully unsaturated bicyclic ring system having 0-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or two occurrences of R? are taken together with the atom(s) to which they are bound to form an optionally substituted 3-12 membered saturated, partially unsaturated, or fully unsaturated monocyclic or bicyclic ring having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; its tautomers or pharmaceutically acceptable salts thereof comprising the steps of;a) coupling indole acetic acid with corresponding amines using suitable coupling agent to obtain indole amides;
b) oxidizing indole amides of step (a) using suitable oxidizing agent followed by treatment with base to obtain desired quinolone carboxamides with 40 to 65% yield, wherein the base is an organic base selected from pyridine, 2,6-lutidine, DMAP (4-dimethylaminopyridine), Et3N (triethylamine), DIPEA (N,N-diisopropyl ethyl amine), N,N-dimethylaniline, DBN (1,5-diazabicyclo(4.3.0)non-5-ene), DABCO (1,4-diazabicyclo[2.2.2]octane) and DBU (1,8-diazabicycloundec-7-ene) or mixture thereof.

US Pat. No. 10,336,702

PHARMACEUTICALLY ACTIVE COMPOUNDS

BerGenBio ASA, Bergen (N...

1. A compound of formula (I):
wherein
one of Q1 and Q2 represents a nitrogen atom and the other represents CH, or both Q1 and Q2 represent nitrogen atoms, and Q3 represents CH;
A represents an optionally substituted five- or six-membered aromatic ring;
R1 represents an aliphatic carbocyclic or heterocyclic ring, optionally substituted by —(C?O)xNRaRb, —ORc, —SO2Rg or optionally substituted alkyl, in which
x is 0 or 1;
Ra and Rb independently represent (a) H, (b) optionally substituted alkyl, (c) optionally substituted cycloalkyl, (d) optionally substituted heterocycloalkyl, (e) —(C?O)Rd, or (f) —SO2Re, wherein Rd and Re independently represent (i) optionally substituted alkyl, (ii) optionally substituted alkoxy, or (iii) optionally substituted cycloalkyl; or Ra and Rb together with the nitrogen atom to which they are attached form an optionally substituted aromatic or aliphatic heterocyclic ring;
Rc represents optionally substituted alkyl;
and
Rg represents optionally substituted cycloalkyl;
R2 represents H, optionally substituted alkyl or halo;
R3 represents an optionally substituted aryl or heteroaryl ring;
R5 and R6 independently represent H or optionally substituted alkyl; or R5 and R6 together with the carbon atom to which they are attached form an optionally substituted cycloalkyl ring, optionally containing a heteroatom;
and the corresponding N-oxides; and pharmaceutically acceptable salts and solvates of such compounds and their N-oxides and prodrugs.

US Pat. No. 10,336,641

METHOD FOR PRODUCING A FOAM GLASS WITH HIGH OPEN PORE CONTENT

Ngee Ann Polytechnic, Si...

1. A method for producing foam glass comprising the steps of:combining glass particles with foaming agents, additives and a binding agent to form a mixture;
compressing the mixture in a mold with a compression pressure between 2 MPa and 20 MPa for a period of time between 30 seconds and 15 minutes to form a compressed sample;
de-molding the sample and curing the sample;
heating the sample to a first elevated temperature and maintaining the sample at the first elevated temperature for a first period of time to decompose a part of the foaming agents;
heating the sample from the first elevated temperature to a second elevated temperature and maintaining the sample at the second elevated temperature for a second period of time to decompose the remainder of the foaming agents;
cooling the sample from the second elevated temperature to a first lowered temperature for a third period of time to anneal the sample; and
cooling the sample from the first lowered temperature to an ambient room temperature, the cooled sample having open pore content between 88% and 95%, compression strength between 2.1 MPa and 2.8 MPa, and bulk densities between 0.17 g cm?3 and 0.22 g cm?3.

US Pat. No. 10,336,632

SYSTEMS AND METHODS FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH

Greencentre Canada, King...

1. A system for modulating an osmotic gradient across a membrane comprising:a switchable water comprising water and an additive switchable between a first form and a second form, wherein said second form of the additive is water-miscible or water soluble and includes at least one ionized functional group that is neutral in said first form of the additive, such that switching the additive from the first form to the second form increases the ionic strength of the switchable water;
wherein the additive is a polymer, and wherein the at least one functional group is an amine;
a source of an ionizing trigger, wherein the ionizing trigger ionizes the at least one functional group in the additive and thereby increases the ionic strength of the switchable water; and
a semi-permeable membrane that is selectively permeable for water, wherein the switchable water contacts a first side of the semi-permeable membrane, and a feed stream contacts a second side of the semi-permeable membrane;
wherein the system modulates the osmotic gradient across said membrane via modulating the ionic strength of the switchable water.

US Pat. No. 10,336,631

WASTEWATER TREATMENT METHOD AND WASTEWATER TREATMENT APPARATUS

MITSUBISHI HEAVY INDUSTRI...

1. A wastewater treatment method of treating wastewater including -2-valent selenium, 0-valent selenium, 4-valent selenium, and 6-valent selenium, the method including the steps:a removing step of removing -2-valent selenium included in the wastewater by using silver chloride as a remover which is generated by reacting hydrochloric acid with a silver nitrate while the wastewater is supplied with outside air to remove volatile substances from the wastewater, in an aeration tank;
a reducing step of reducing the 6-valent selenium included in the wastewater into at least one of 0-valent selenium and 4-valent selenium by using ferrous chloride as a reductant after the removing step, in a reaction tank; and
a coprecipitation treatment step of separating the 0-valent selenium and the 4-valent selenium which remain or are reduced in the wastewater from the wastewater by coprecipitation with iron hydroxide by using ferric chloride as a coprecipitation agent after the reducing step, in a deposition tank.

US Pat. No. 10,336,627

INFUSION APPARATUS

Helen of Troy Limited, S...

1. A water filter and infusion apparatus comprising:a housing including a reservoir;
an unfiltered water pour tray disposed at least partially within the housing, the unfiltered water pour tray having a bottom wall and an opening disposed through the bottom wall;
a filter cartridge, a portion of which extends partially through the opening and below the bottom wall of the pour tray; and
an infuser having an infuser reservoir, a plurality of apertures disposed within the infuser, and a connector removably connecting the infuser to the filter cartridge.

US Pat. No. 10,336,626

NICKEL COBALT COMPLEX HYDROXIDE PARTICLES AND METHOD FOR PRODUCING THE SAME, POSITIVE ELECTRODE ACTIVE MATERIAL FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY AND METHOD FOR PRODUCING THE SAME, AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY

NICHIA CORPORATION, Anan...

1. A method for producing a nickel cobalt complex hydroxide represented by a general formula: Ni1-x-yCoxMnyMz(OH)2+a, wherein 0.10?x?0.35, 0 after the first crystallization, second crystallization of further supplying to the reaction container containing the first complex hydroxide particles a solution containing nickel ion, cobalt ion, and manganese ion, a solution of a complex ion forming agent, a basic solution, and a solution containing said element M separately and simultaneously to crystallize a second complex hydroxide particles containing nickel, cobalt, manganese and said element M on the first complex hydroxide particles;
wherein assuming that a total molar amount of nickel, cobalt and manganese supplied in the first crystallization is MOL(1) and that a total molar amount of nickel, cobalt and manganese supplied in the second crystallization is MOL(2), MOL(1) and MOL(2) satisfy an inequality of 0.30?MOL(1)/{MOL(1)+MOL(2)}<0.95.

US Pat. No. 10,336,624

METHOD OF PRODUCING HIGH-PLURALITY LITHIUM CARBONATE BY CONTROLLING PARTICLE SIZE, PARTICLE SIZE DISTRIBUTION, AND PARTICLE SHAPE

KANGWON NATIONAL UNIVERSI...

1. A method of producing high-purity lithium carbonate from low-purity crude lithium carbonate by controlling a particle size, a particle size distribution, and a particle shape, the method comprising steps of:(a) producing crude lithium carbonate slurry by mixing low-purity crude lithium carbonate having a polycrystalline state and a size of 20 to 200 ?m with water;
(b) carbonating and dissolving the crude lithium carbonate slurry;
(c) performing primary solid-liquid separation for the carbonated crude lithium carbonate slurry to obtain a filtrate;
(d) adding soluble barium salts to the filtrate obtained in the primary solid-liquid separation to deposit barium sulfate;
(e) performing secondary solid-liquid separation for the filtrate containing the deposited barium sulfate to obtain a filtrate;
(f) mixing lithium carbonate seed crystals with the filtrate obtained from the secondary solid-liquid separation and precipitating lithium carbonate dissolved in the filtrate on surfaces of the lithium carbonate seed crystals to produce high-purity lithium carbonate slurry containing high-purity lithium carbonate; and
(g) carbonating the high-purity lithium carbonate slurry to produce high-purity lithium carbonate.

US Pat. No. 10,336,622

CRYSTALLINE METALLOPHOSPHATES, THEIR METHOD OF PREPARATION, AND USE

UOP LLC, Des Plaines, IL...


US Pat. No. 10,336,619

METHOD FOR THE SYNTHESIS OF GRAPHENE OXIDE

Sri Lanka Institute of Na...

1. A method of synthesizing graphene oxide with an X-ray diffraction spectrum having a single dominant peak at a two theta angle below 10 degrees without the use of H3PO4 or a nitrogen-containing compound comprising:a. providing a graphite source;
b. reacting the graphite source with H2SO4 in a vessel;
c. adding KMnO4 to the vessel to form a reaction mixture, wherein the H2SO4, graphite source, and KMnO4 are maintained at a temperature between 0° C. and 10° C. from the addition of the H2SO4 through reaction with KMnO4 for a period of more than 8 hours;
d. adding H2O2 and H2O to the reaction mixture in order to create a supernatant and a graphene oxide slurry; and
e. separating the supernatant in order to obtain the graphene oxide slurry.

US Pat. No. 10,336,617

METHOD OF SYNTHESIZING SOLUBLE POLYPHOSPHIDES FROM RED PHOSPHOROUS USING SHELF-STABLE REAGENTS AND ORGANIC SOLVENTS

The Florida State Univers...

1. A method for producing polyphosphide anions soluble in organic solvents, comprising:providing red phosphorus or a composition of black phosphorus and red phosphorus;
providing an alkali metal alkoxy compound or alkali metal alkyl thiolate compound suspended in an organic solvent;
wherein the alkali metal is sodium or potassium;
allowing the red phosphorus and alkali metal or alkali metal compound to react, wherein the reaction uses reflux or an in-line packed column method;
where the in-line packed column method comprises:
providing a packing column;
loading the packing column with the red phosphorus or composition of black phosphorus and red phosphorus in an inert environment;
purging the packing column with an inert gas;
setting a pressure regulator on the packing column to at least 1 bar;
heating the packing column to a preselected temperature, where the preselected temperature is at least the boiling point of the alkali metal alkoxy compound or alkali metal alkyl thiolate and wherein the temperature of the packing column or a reaction solution does not exceed the critical temperature of the organic solvent;
suspending the alkali metal alkoxy compound or alkali metal alkyl thiolate compound in the organic solvent;
flowing the organic solvent through the packing column;
flowing the alkali metal alkoxy compound or alkali metal alkyl thiolate compound in the organic solvent through the packing column;
forming a compound containing the alkali metal and polyphosphide anions;
evaporating the organic solvent off the compound containing the alkali metal and polyphosphide anions;
redissolving the compound containing the alkali metal and polyphosphide anions in ethanol;
subjecting the compounds containing alkali metal and polyphosphide anions to a cation exchange with (Bu4N)Cl in ethanol to produce a cation-polyphosphide material;
redissolving the cation-polyphosphide material in acetonitrile to form free polyphosphide anions; and
separating the black phosphorus from the polyphosphide anions;
wherein the reflux is performed for about 15 minutes to about 2 hours.

US Pat. No. 10,336,616

METHOD OF CONVERTING RED PHOSPHOROUS TO SOLUBLE POLYPHOSPHIDES USING POTASSIUM ETHOXIDE

The Florida State Univers...

1. A method for producing polyphosphide anions soluble in organic solvents, comprising:providing red phosphorus or a composition of black phosphorus and red phosphorus;
providing potassium ethoxide suspended in an organic solvent;
allowing the red phosphorus and the potassium ethoxide to react, wherein the reaction uses reflux or an in-line packed column method;
where the in-line packed column method comprises:
providing a packing column;
loading the packing column with the red phosphorus or composition of black phosphorus and red phosphorus in an inert environment;
purging the packing column with an inert gas;
setting a pressure regulator on the packing column to at least 1 bar;
heating the packing column to a preselected temperature, where the preselected temperature is at least the boiling point of the potassium ethoxide;
suspending the potassium ethoxide in the organic solvent;
flowing the organic solvent through the packing column;
flowing the potassium ethoxide in the organic solvent through the packing column; and
forming a compound containing potassium metal and polyphosphide anions.

US Pat. No. 10,336,614

HYDROGEN SULFIDE PRODUCTION PROCESS AND RELATED REACTOR VESSELS

Chevron Phillips Chemical...

1. A H2S production process comprising:(i) controlling a reaction chamber containing liquid sulfur at a start-up temperature above the melting point of sulfur with an external heating system comprising a heated reactor conduit conductively and removably attached to an exterior surface of the reaction chamber;
(ii) adding liquid sulfur to the reaction chamber to a level sufficient to immerse an internal heating system positioned within the reaction chamber;
(iii) engaging the internal heating system to reach and maintain an operating temperature of the liquid sulfur of at least about 300° C.;
(iv) adding a hydrogen-containing gas into the liquid sulfur and reacting to produce H2S; and
(v) optionally, discontinuing the operation of the external heating system.

US Pat. No. 10,336,605

MICRO ELECTRO MECHANICAL SYSTEMS SENSOR

Samsung Electro-Mechanics...

1. A MEMS sensor, comprising:a mass body;
a support part floatably supporting the mass body; and
a flexible beam having one end connected to the mass body and another end connected to the support part,
wherein one of the ends of the flexible beam extends into an intermediate portion of an opening in a connection part having an arcuate contour, and
wherein the connection part is formed at a terminal end of the flexible beam.

US Pat. No. 10,336,604

BREAKAWAY HOSE SUPPORT

OPW FUELING COMPONENTS, L...

1. A fluid dispensing system comprising:a support structure;
a hose configured to dispense fluid therethrough;
a support cable directly or indirectly coupled to said hose, wherein said hose is directly or indirectly releasably coupled to said support structure via said cable and a breakaway assembly, said breakaway assembly including a first portion coupled to the cable, a second portion coupled to the hose by a pin oriented transverse to an axis of the hose and defining a pivot axis, and a third portion configured to releasably attach said first and second portions and to allow separation of said first and second portions by deformation of said third portion and not breakage thereof when a predetermined force is applied thereto by said cable; and
an extension and retraction mechanism configured to provide an adjustable effective length to said cable.

US Pat. No. 10,336,600

LOCKING AND EMPTYING SYSTEM OF REFILL CARTRIDGE CONTAINING NUTRIENTS OR CHEMICALS

1. A locking and emptying system of a refill cartridge (1) containing nutrients or chemicals, said locking and emptying system comprising at least one receiving socket (2) for locking and emptying the refill cartridge (1), in every said receiving socket (2) a locking mechanism of the refill cartridge (1), discharge means of the refill cartridge (1) and control means of the locking and empting system and for the refill cartridge (1) a emptying container (3), characterized in thatin the vicinity of the insertion end of the refill cartridge (1) to be inserted into the receiving socket of an upper face (4) of the refill cartridge (1) comprises a locking depression (5);
the locking mechanism in the receiving socket (2) comprises a lever mechanism (6) operable by an end face (11) of the refill cartridge (1), said lever mechanism (6) comprising four mutually rigidly connected parts (7, 8, 9, 10) having mainly parallel longitudinal axes, said longitudinal axes are crosswise to the insertion direction of the refill cartridge (1);
where in the receiving socket (2) first part (7) of the lever mechanism (6) is placed rotatably around the longitudinal axis of second part (8) together with third part (9) and fourth part (10) and
where said first part (7), third part (9) and fourth part (10) are biased to rotate around the longitudinal axis of said second part (8) so that said first part (7) is pressed against end face (11) of the refill cartridge (1);
where in the position where said refill cartridge (1) is inserted into the receiving socket (2) with its end thee (11), said end face (11) is pressed against the first part (7) of the lever mechanism (6), as a result said first part (7) is rotatable around the second part (8) of the lever mechanism (6) together with said third (9) and fourth part (10) of the lever mechanism (6); and
where in the position where said refill cartridge (1) is pressed completely into the receiving socket (2), said first part (7) pressed against the end face (11) of the refill cartridge (1) is rotated around the second part (8) of the lever mechanism (6) together with third part (9) and fourth part (10) of the lever mechanism (6) so that said fourth part (10) is engaged with the locking depression (5) on the upper face (4) of the refill cartridge (1) to the locked position of the refill cartridge (1) in the receiving socket (2), where said lever mechanism (6) is locked into a holding position by the third part (9).

US Pat. No. 10,336,597

CAPSULE-BASED ALCOHOLIC BEVERAGE FORMING APPARATUS AND COMPONENTS THEREOF

Altria Client Services LL...

1. An alcoholic beverage forming apparatus operable to dispense an alcoholic beverage, the alcoholic beverage forming apparatus comprising:a capsule holder configured to receive a beverage capsule having a flavor medium in an interior thereof;
a water supply reservoir operable to supply water to a mixing manifold of the alcoholic beverage forming apparatus at a predetermined temperature;
an alcohol supply reservoir operable to supply alcohol to the mixing manifold of the alcoholic beverage forming apparatus at a predetermined temperature;
a dispenser operable to dispense the alcoholic beverage therefrom;
wherein predetermined amounts of the water and alcohol supplied to the mixing manifold are combined therein so as to form an alcoholic beverage mixture having a desired proof, temperature, and volume, and the alcoholic beverage forming apparatus is operable to supply the alcoholic beverage mixture through an outlet of the mixing manifold to an interior of the beverage capsule held in the capsule holder during use of the alcoholic beverage forming apparatus such that the alcoholic beverage mixture mixes with the flavor medium contained in the interior of the beverage capsule to form the alcoholic beverage that is dispensed from the dispenser of the alcoholic beverage forming apparatus;
a carbonated water reservoir operable to supply carbonated water to the mixing manifold of the alcoholic beverage forming apparatus to carbonate the alcoholic beverage; a consumer interface configured to receive consumer input information and a controller operable to control processes performed by the beverage forming apparatus, a data matrix scanner operable to read data of a matrix positioned on the beverage capsule containing the flavor medium wherein the data of the matrix includes recipe information for the alcoholic beverage; a lighting or sound effects component operable to provide lighting or sound effects during use of the alcoholic beverage forming apparatus; a portable power supply; a fill level sensor operable to determine a level of an alcoholic beverage that has been dispensed into a drinking vessel during operation of the alcoholic beverage forming apparatus wherein the fill level sensor is operable to stop the alcoholic beverage forming apparatus from further dispensing an alcoholic beverage if a dispensed alcoholic beverage reaches an upper opening of the drinking vessel or has filled the drinking vessel to a predetermined level; a drain below the dispenser; a mixer reservoir operable to supply a flavored mixer to the mixing manifold of the alcoholic beverage forming apparatus such that the alcoholic beverage mixture is combined with the flavored mixer in the mixing manifold to flavor the alcoholic beverage mixture before the alcoholic beverage mixture is delivered to an interior of a beverage capsule through the outlet of the mixing manifold; a credit card reader; an ID reader; and a recognition system operable to recognize the type of alcohol in the alcohol reservoir.

US Pat. No. 10,336,589

MOBILE LIFT CRANE WITH VARIABLE POSITION COUNTERWEIGHT

Manitowoc Crane Companies...

1. A method of operating a mobile lift crane, the lift crane comprising a carbody having moveable ground engaging members; a rotating bed rotatably connected to the carbody such that the rotating bed can swing with respect to the ground engaging members; a boom pivotally mounted on the rotating bed, with a hoist line extending therefrom; a mast mounted at a first end of the rotating bed; at least one rack and pinion assembly; and a moveable counterweight unit suspended from a tension member connected to the mast wherein the moveable counterweight unit is adapted to be moved to a far forward position in which the moveable counterweight is positioned forward of a rear most portion of a rear ground engaging member of the moveable ground engaging members; the method comprising:a) performing a pick, move and set operation with a load wherein the moveable counterweight unit is moved toward and away from a front portion of the rotating bed by extending and retracting the rack and pinion assembly during the pick, move and set operation to help counterbalance the load, but wherein the counterweight unit is never supported by the ground other than indirectly by the moveable ground engaging members on the carbody throughout the pick, move and set operation, and wherein the tension member moves compared to the mast as the moveable counterweight moves.

US Pat. No. 10,336,587

HOIST AND CRANE

Professor Cargo, LLC, Li...

1. A truck hoist and crane assembly comprising:a first rail and a second rail each vertically supported, and each longitudinally extending within said hoist and crane assembly, said second rail oriented substantially parallel to said first rail;
a third rail slidably engaged to said first rail and a fourth rail slidably engaged to said second rail, thereby facilitating concurrent longitudinal movement of said third and fourth rails to extend from a rear of the hoist and crane assembly, said third rail and said fourth rail juxtaposed to and parallel to said first and second rails, respectively;
a fifth rail angularly fixed to said third rail and said fourth rail, and, a sixth rail angularly fixed to said third rail and said fourth rail, said fifth rail substantially parallel to said sixth rail; and
a hoist operably fixed to said fifth and sixth rails, said hoist movable from said third rail to said fourth rail, and said hoist extendable and retractable from said first and second rails,
wherein said hoist is operable in both a lateral and longitudinal motion, and, wherein said third rail and said fourth rail are adapted to extend from said first and second rails, respectively.

US Pat. No. 10,336,583

LIFTER AND METHOD FOR MOVING TRAFFIC BARRIERS

Vacuworx Global, LLC, Tu...

1. A method for lifting a traffic barrier, the method comprising:operating a rotator of a barrier lifter connected to a boom, the barrier lifter including
at least one pinned connector configured for connecting the barrier lifter to the boom;
the rotator located below and connected to the at least one pinned connector, the rotator capable of rotating said lifter relative to the boom;
a pair of opposing axes located below the rotator and running parallel to one another;
a pair of opposing arms, each arm connected at an upper end to a respective axis of the pair of opposing axes, the arms rotatable relative to one another between an open position and a closed position; and
a cross-member pivotally connected to a respective lower end of each arm of the pair of opposing arms, the cross-member including a gripping surface;
operating the pair of opposing arms into the open position;
operating the rotator to align the arms with a traffic barrier;
lowering the boom and lifter onto the traffic barrier;
operating the pair of opposing arms into the closed position wherein the gripping surface of each arm is in contact with and applying pressure to a respective opposing surface of the traffic barrier;
lifting the boom, lifter and traffic barrier;
placing the traffic barrier over a desired location;
lowering the boom, lifter and traffic barrier wherein the traffic barrier is placed on the desired location; and
operating the pair of arms to return into the open position.

US Pat. No. 10,336,566

FEED TAPE DISPENSER

Shurtech Brands, LLC, Av...

15. A tape dispenser comprising a frame having a top wall and opposed side walls, said top wall connecting the opposed side walls; a tape mount disposed on an interior surface of each of the side walls and being adapted to secure a roll of tape therebetween; a cutter blade disposed on a forward region of the frame and adapted to cut tape from the roll; a bar disposed on the interior surface of one side wall, said bar comprising a hollow semi-cylinder extending between greater than 40% and less than 90% of a distance between said opposed side walls to provide a space between an end of the bar and one side wall.

US Pat. No. 10,336,561

ARTICLE LOADING FACILITY

DAIFUKU CO., LTD., Osaka...

1. An article loading facility comprising:a loading unit that loads a plurality of target articles onto one first supporting member;
a first control unit that controls the loading unit; and
a setting unit that performs an arrangement setting process to set arrangement information for each of the plurality of target articles that are to be loaded onto the first supporting member, the arrangement information indicating the orientation and the position of the corresponding target article relative to the first supporting member,
wherein:
the first control unit controls the loading unit based on the arrangement information so that the plurality of target articles are loaded onto the first supporting member according to the respective orientations and positions of the plurality of target articles indicated by the arrangement information,
the article loading facility further includes: storage units that store therein second supporting members that support the target articles on a type-by-type basis; a transport unit that transports the second supporting members from the storage units to a transfer position, and transports the second supporting members from the transfer position to the storage units; and a second control unit that controls the transport unit,
the loading unit takes out target articles that are supported by a second supporting member that is located at the transfer position, and loads the target articles onto the first supporting member,
in the arrangement setting process, the setting unit performs an arrangement order setting process to set the arrangement information that indicates an arrangement that, after all target articles of a first type have been loaded onto the first supporting member, allows all target articles of a second type, which is different from the first type, onto the first supporting member, and to set a type arrangement order that, when target articles of a plurality of types are to be loaded according to the arrangement information, indicates the order in which the plurality of types are to be arranged,
the second control unit controls the transport unit to transport the second supporting members to the transfer position according to the type arrangement order, and
the first control unit controls the loading unit to load the target articles onto the first supporting member according to the arrangement information that has been set in the arrangement setting process.

US Pat. No. 10,336,534

SELF-CLEANING TANK

Spokane Industries, Spok...

1. A container comprising:a tank for holding a product, the tank comprising:
a top surface;
a bottom surface opposite the top surface, the bottom surface having a perimeter and defining a first plane, and the bottom surface having a non-zero slope relative to a horizontal plane;
a vertical wall fixed to the perimeter of the bottom surface and between the bottom surface and the top surface, the bottom surface extending substantially around a perimeter of the vertical wall;
an aperture arranged in the vertical wall of the tank, a portion of the aperture arranged at the perimeter of the bottom surface of the tank and adjoining with the bottom surface; and
a scraper blade assembly rotatably coupled to the bottom surface of the tank, the scraper blade assembly comprising a blade having a rotational path in a second plane parallel to the first plane, the blade comprising:
a first leading surface opposite a first trailing support structure, the first leading surface having a curvilinear shape spanning a first portion of the blade;
a first scraping member attached to a first end of the first portion of the blade;
a second leading surface opposite a second trailing support structure, the second leading surface having the curvilinear shape spanning a second portion of the blade;
a second scraping member attached to a second end of the second portion of the blade; and
one or more bottom scraping members arranged on the first leading surface and arranged on the second leading surface respectively to contact the bottom surface of the tank;
wherein when the blade is rotatably displaced in the second plane,
the one or more bottom scraping members maintain contact with the bottom surface of the tank,
the curvilinear shape of the first leading surface and the curvilinear shape of the second leading surface of the blade displaces solids deposited on the bottom surface of the tank in a direction towards the vertical wall of the tank, and
at least a portion of the first scraping member and at least a portion of the second scraping member extend through the aperture when the first scraping member and the second scraping member pass by the aperture to displace the solids deposited on the bottom surface of the tank through the aperture to clean the tank.

US Pat. No. 10,336,531

CAPSULE WITH STEEPING CHAMBER

2266170 Ontario Inc., Mi...

1. A capsule, for use in a machine for preparing consumable products from capsules, said machine having an injection system that includes at least one injection nozzle for injecting heated fluid into said capsule at a predetermined flow rate, said capsule comprising:a body defining an interior space with an opening;
a cover disposed over said opening, said cover being formed of a material that is heat shrinkable and resistant to tearing so as to shrink sufficiently around said at least one injection nozzle when said at least one injection nozzle pierces said cover and injects heated fluid into said capsule, to create a seal that allows pressure to build within said interior space beneath said cover up to a maximum pressure;
a filter disposed in said interior space to define a steeping chamber between said filter and said cover, said filter being formed of one or more materials that are sufficiently phobic to said heated fluid to cause said steeping chamber to fill with fluid without exceeding said maximum pressure; and
ingredients disposed in said steeping chamber for preparing a desired product,
wherein said filter is constructed and arranged to restrict a flow of the fluid through said filter to optimize extraction or infusion of said ingredients disposed within said steeping chamber.

US Pat. No. 10,336,529

POLYOLEFIN PACKING CONTAINER

TOYO SEIKAN GROUP HOLDING...

1. A polyolefin packing container having on the inner surface thereof an olefin resin layer that contains an ethylenebisfatty acid amide, wherein said ethylenebisfatty acid amide is bleeding in said inner surface in an amount of 12.5 to 200 mg/m2;wherein said ethylenebisfatty acid amide exhibits a plurality of endothermic peaks in a region of 40 to 130° C. on a heating-up profile (differential thermal curve) as measured by a differential scanning calorimetry;
wherein said ethylenebisfatty acid amide is partly ethylenebisoleic acid amide, and the rest is a compound represented by the following formula (1),
R1—CONH—CH2—CH2—NHCO—R2  (1)
wherein R1 and R2 may be the same or different, and are unsaturated or saturated aliphatic hydrocarbon groups having 14 to 22 carbon atoms, and either R1 or R2 in the above formula (1) is a saturated aliphatic hydrocarbon group; and
wherein at least 3% of said ethylenebisfatty acid amide is said half-saturated bisamide on condition that not less than 55% of said ethylenebisfatty acid amide is the ethylenebisoleic acid amide as measured by a liquid chromatography.

US Pat. No. 10,336,522

PACKAGING

Consolidated Graphics, In...

1. A packaging, comprising:a first panel including a first end, a first central portion, and a second end, opposing perimeter side edges defining the first panel and extending between the first end and the second end, a first area having an inside surface and defined by the first end, the second end, and the perimeter side edges;
a second panel including a third end, a second central portion, and a fourth end, a second area defined by the third end and the fourth end, wherein the second end is coupled to the third end at a first fold line, and the first panel is substantially identical to the second panel; and
a first flap extending from a first side of the second central portion at a second fold line and a second flap extending from a second side of the second central portion at a third fold line, wherein when the first panel is folded toward the second panel about the first fold line and the first and second flaps are folded about the second and third fold lines, respectively, the first and second flaps engage the inside surface of the first area and couple the first panel and the second panel;
wherein when the first panel is folded toward the second panel about the first fold line the inside surface of the first end of the first panel is secured to the fourth end of the second panel; and
the first area and the second area are free of fold lines and flaps.

US Pat. No. 10,336,512

CLOSURE SYSTEM WITH HINGE HAVING UNIFORM THICKNESS AND ELEVATED CENTER

PHOENIX CLOSURES, INC., ...

1. A closure for engaging with a neck of a container comprising:a body member comprising a base wall and a body skirt, the body skirt for engaging the neck of the container;
a cap member comprising a top wall and a cap skirt, the cap member movable between an open position and a closed position, the cap member in the closed position engaging the body member, and the cap member in the open position indirectly contacting the body member via a hinge member; and
the hinge member having a uniform thickness throughout the hinge member, the hinge member comprising two hinge portions separated by an opening, each hinge portion attaching the body member to the cap member, and each hinge portion defining a line between the body member and the cap member when the cap member is in the open position;
wherein when the cap member is in the open position, each hinge portion comprises an elevated central segment and end segments on opposite sides of the central segment, the elevated central segment including top and bottom surfaces that are parallel to, but not coplanar with, top and bottom surfaces of the end segments.

US Pat. No. 10,336,509

SLIDE AND LOCK PACKAGE WITH FILM SEALABLE TRAY

Sonoco Development, Inc.,...

1. A reclosable container comprising:a tray having two lateral sides and comprising a bottom wall, two laterally opposing side walls, a front wall and a rear wall;
the bottom wall having a periphery, the side walls, the front wall and the rear wall each extending upward from the periphery and terminating in a rim;
the bottom wall, the side walls, the front wall and the rear wall defines one or more compartment within the tray for holding a product or products;
the tray further comprising a flat, continuous top wall extending outwardly from the rim and adapted to accept a flexible film in sealing engagement therewith;
the tray further comprising a skirt extending downward from the top wall and a flange extending outwardly from the skirt;
the skirt defining a groove on either lateral side of the tray that extends inwardly from the skirt; and
a lid comprising a cover portion that covers the one or more compartments, two lid side walls extending downward from the cover portion and a lid side flange extending laterally outward from each of the lid side walls;
each lid side wall forming an inwardly extending rib, each rib adapted to slide axially within a corresponding groove in the tray; wherein
the lid is moveable in a sliding fashion relative to the tray between a fully closed position in which the cover portion completely covers the one or more compartments and an open position in which the cover portion does not completely cover the one or more compartments.

US Pat. No. 10,336,503

CONTAINER WITH GRIP STRUCTURE

Graham Packaging Company,...

1. A container comprising:a top portion comprising a finish portion;
a body portion disposed below the top portion; and
a bottom portion disposed below the body portion opposite the top portion;
the body portion comprising:
a front wall,
a rear wall opposite the front wall,
first and second side walls extending between the front wall and the rear wall to define a generally rectangular shape in plan view, the first side wall disposed opposite the second side wall,
opposing grip areas formed in the first and second side walls, the opposing grip areas including a first grip area formed in the first side wall and a second grip area formed in the second side wall,
a first circumferential rib disposed above the opposing grip areas and extending horizontally about an entire outer circumferential perimeter of the body portion,
a second circumferential rib disposed below the opposing grip areas and extending horizontally about the entire outer circumferential perimeter of the body portion,
at least one horizontal body rib disposed between the first and second circumferential ribs and spaced from the opposing grip areas, and
a first vertical strut formed in the first side wall and spaced from the first grip area and a second vertical strut formed in the second side wall and spaced from the second grip area, each of the first and second vertical struts disposed between and spaced from the first and second circumferential ribs and having a length coextensive with a height of the first and the second grip areas respectively, the first and second vertical struts configured to resist radially-inward distortion of the first and second side walls from gripping the opposing grip areas.

US Pat. No. 10,336,495

CONTAINER COMPRISING A SINGLE-PIECE HEAD SECTION

KOCHER-PLASTIK MASCHINENB...

1. A container, comprising:a container body capable of receiving a fluid;
a neck section being connected to said container body and having a dispensing opening at a free end of said neck section capable of dispensing the fluid from said container body;
a head section being removably connected to said neck section by a separating region and releasably sealing said dispensing opening closed; and
a movable sleeve section being coupled to said neck section and being actuatable to remove said head section from said neck section by releasing said separating region to open said dispensing opening, said movable sleeve section being movable from an unactuated state in which said dispensing opening is closed to an actuated state in which said separating region is released and being guided by being at least partially in contact with a guide path that is part of said head section, said guide path being formed on an outside of a ring collar surrounding said head section and extending between said separating region and an annular groove on said head section, said ring collar having an axial extension with a length of said annular groove measured on a smallest diameter size thereof.

US Pat. No. 10,336,493

DEVICE AND PROCESS FOR APPLYING GRIPPING HANDLES ON PACKAGING FILMS, AND SHRINKWRAP PACKER PROVIDED WITH SUCH A DEVICE

OCME S.R.L., Parma (IT)

1. Device for applying gripping handles on heat-shrinkable packaging films, being supplied on shrinkwrap packers for making bundles of bottles and/or cans, the applying device comprising:at least one applying head provided with at least one roller for applying a plurality of gripping handles supplied in the form of a continuous tape and subsequently cut into sections;
at least one abutment mechanism for operatively supporting a plurality of packaging films in the form of a continuous tape and subsequently cut into sections, optionally heat-shrinkable, being supplied on a respective shrinkwrap packer on which the applying device is mounted, the roller for applying of the applying head and the abutment mechanism being movable with respect to one another between a non-operating condition, in which the roller for applying of the applying head is spaced apart from the abutment mechanism, and an operating condition, wherein the roller for applying of the applying head is arranged, at the abutment mechanism, against at least one of the packaging films being supplied for applying a respective gripping handle on such packaging film,
wherein the abutment mechanism comprising at least one supporting tape, higher than the width of the packaging films being supplied, having an advancement surface facing, at least partially, the applying head for advancing the packaging films being supplied on the shrinkwrap packer, the advancement surface of the supporting tape providing, in the operating condition, an abutment for the roller for applying of the applying head, the roller for applying of the applying head applying a gripping handle on each packaging film being supplied, against the advancement surface of the supporting tape; and
wherein the supporting tape extends according to a ring-shaped development, substantially triangular, the supporting tape being movably actuated according to the same advancement direction of the packaging films being supplied on the shrinkwrap packer for carrying these packaging films in advancing along the applying head.

US Pat. No. 10,336,492

SEALING JAWS FOR BAGGING APPARATUS

DYCO, INC., Bloomsburg, ...

1. A sealing jaw for use with a bagging apparatus comprising:a removable jaw having a guide/retention member selectively releasable in a first direction from a jaw holder;
the jaw holder comprising:
a retainer assembly having a release member movable between a first position for securing the guide/retention member therewith, and a second position for releasing the guide/retention member therefrom; and
wherein in response to a force being applied to the release member in a direction away from the jaw holder opposite the first direction urging the release member toward the first position, a dog is urged into engagement with the guide/retention member;
wherein in response to a force being applied to the release member in a direction toward the jaw holder in the first direction urging the release member toward the second position, the release member urging the dog into disengagement with the guide/retention member.

US Pat. No. 10,336,491

PACKAGING METHOD AND APPARATUS

MSK-VERPACKUNGS-SYSTEME G...

1. An apparatus for wrapping a stack of objects having, relative to a horizontal and longitudinal travel direction, first and second transversely spaced and vertical side faces extending parallel to the direction, a vertical front face transversely bridging front ends of the side faces, a vertical rear face transversely bridging rear ends of the side faces, and a horizontal top face extending between upper ends of the front, rear and side faces, the apparatus comprising:at least one conveyor for advancing the stack in the horizontal and longitudinal travel direction;
means for wrapping a film wrapper around the stack such that respective first side, second side, front, and rear film sections of the film wrapper extend upward from the respective faces past the top face;
a first welder for welding ends of the film wrapper at one of the faces of the stack;
a fold-over device having first and second pairs of transversely spaced, parallel, and upright film-guide plates all extending parallel to the travel direction, the plates of each pair being transversely fixed to each other and jointly transversely movable from an outer position above the respective side face and with the first pair of guide plates confronting the second pair of guide plates perpendicular to the direction into an inner position with the two pairs of plates closely juxtaposed centrally above the stack, the two pairs of plates being so oriented that in the outer position the first and second side film sections project up from the respective first and second side faces of the stack past the top face and are received between the guide plates of the respective first and second pairs, the first and second pairs of plates being movable transversely of the direction toward one another from the outer position for pulling the respective first and second side film sections from between the respective plates and laying the first and second side film sections onto the top face of the stack;
respective first and second fold-over members on the first and second pairs of film-guide plates and movable in the travel direction from downstream of the rear face to fold the rear film section over onto the top face of the stack; and
a second welder for welding the folded-over film sections onto the top face of the stack.

US Pat. No. 10,336,489

PACKAGING MACHINE

AUTOMATED PACKAGING SYSTE...

1. An apparatus for making packages, comprising:an indexing mechanism configured to receive a web of connected bags;
a blower configured to blow air into an opening of a bag;
an engagement device, the engagement device comprising:
a first pair of grippers for gripping a first ply of the bag;
a second pair of grippers for gripping the first ply of the bag, wherein the second pair of grippers are spaced apart from the first pair of grippers;
a third pair of grippers for gripping a first side edge of the bag;
a fourth pair of grippers for gripping a second side edge of the bag, wherein the third pair of grippers and fourth pair of grippers are movable relative to each other;
wherein movement of the third and fourth pair of grippers toward each other when each of the pairs of grippers is gripping the bag causes the first and second side edges of the bag to move toward each other to form the opening of the bag into a rectangular opening;
a sealing member configured to seal the opening of the bag.

US Pat. No. 10,336,487

PROCESS FOR THE MANAGEMENT OF A FLOW OF MATERIAL ALONG A RESPECTIVE PLANT

PULSAR S.R.L., Castel Ma...

1. A process for managing a flow of material along a direction of feed of a plant for making and packing articles obtained from semi-finished products in the form of elongate pieces or elements made of paper-based material, comprising:packing the articles to form respective packs containing one or more of the articles housed in a respective container or wrapper, the plant used by the process including a plurality of plant sections including at least each of a rewinding machine that supplies the semi-finished products, an apparatus for making and packing the articles from the semi-finished products, an accumulation section, and a control unit,
the apparatus for making and packing the articles located downstream from the rewinding machine along the direction of feed and having working sections along one or more working lines for making and for packing the articles, respectively,
the accumulation section configured for accumulating or storing the semi-finished products, from which the apparatus for making and packing the articles receives the semi-finished products and which in turn receives the semi-finished products from the rewinding machine that supplies the semi-finished products, and
the control unit, which includes an electronic processing system controlled through corresponding program instructions, being configured to
detect filling values representative of a filling level of the semi-finished products in the accumulation section,
provide a continuous comparing of the filling values with a predetermined filling level, and
generate operating instructions for varying a speed of the apparatus for making and packing the articles, which is located upstream of the accumulation section, in such a way as to vary continuously a number of articles processed per unit of time by the apparatus for making and packing the articles, so that the semi-finished products in the accumulation section are kept at the predetermined filling level.

US Pat. No. 10,336,484

APPARATUS AND METHOD FOR HELICALLY WRAPPING ARTICLES

OAKBRIDGE INVESTMENTS LIM...

7. A packaging apparatus comprising:a wrapping material applicator for helically wrapping articles;
an inlet conveyor for transporting unwrapped articles to the applicator;
an outlet conveyor for transporting wrapped articles away from the applicator, wherein the outlet conveyor comprises
a first conveyor, and
a second conveyor adjacent to and downstream of the first conveyor; anda controller arranged to selectively vary the linear velocity of the second conveyor relative to the linear velocity of the first conveyor so as to separate, or increase the separation of, collations of one or more articles on the outlet conveyor;wherein the packaging apparatus comprises a cutting member arranged to cut wrapping material extending between the spaced collations of articles, as gaps between the collations pass the cutting member, so as to disconnect the spaced collations of articles.

US Pat. No. 10,336,465

ICE CRYSTALS AND VOLCANIC ASH DETECTION SYSTEM

THE REGENTS OF THE UNIVER...

1. A system for detecting ice crystals and/or volcanic ash in an airspace of interest along a flight path of an airborne vehicle, the system comprising:a probe configured to collect an air sample in the airspace of interest;
a radon detection system having a radon activity sensor measuring radon activity in the air sample and outputting a radon activity signal;
a processing unit configured to determine if the radon activity is above a predetermined critical radon value for the airspace of interest, the predetermined critical radon value being greater than a non-convective background level for the airspace of interest, the processing unit configured to compare the radon activity signal to the predetermined critical value and output a radon determination signal indicative of recent convective updraft from lower troposphere;
a spectral detection system configured to determine if ice crystals and/or volcanic ash are present in the airspace of interest when the radon activity is above the predetermined critical radon value and output an ice/ash detection signal, the spectral detection system having an optical sensor configured to measure radiance, emittance, and/or reflectance at spectral bands of interest on opposing sides of at least one crossover point in the airspace of interest; and
the processing unit configured to determine a ratio of the measured radiance, emittance, and/or reflectance at the spectral bands and if the ratio is above a predetermined critical ratio value output an ice/ash determination signal indicative of the presence of ice crystals and/or volcanic ash in the airspace of interest.

US Pat. No. 10,336,421

PROPELLER AND RELATIVE METHOD FOR FINE ADJUSTING THE FLUID DYNAMIC PITCH OF THE PROPELLER BLADES

MAX PROP S.R.L., Milan (...

1. A propeller comprising:at least one propeller cylindrical casing,
a hub, adapted to be coupled to an engine, and mounted inside said propeller cylindrical casing,
at least one blade rotatable pivoted to said propeller cylindrical casing,
said hub being rotatable with respect to said propeller cylindrical casing, or vice versa, for an at least one non-zero angular interval (?) for the adjustment of the fluid-dynamic pitch of said at least one blade,
said hub comprising at least one contact surface movable between at least one direct or indirect disengagement position, and at least one direct or indirect engagement position with an at least one relative limit stop abutment of said at least one non-zero angular interval (?), and
said limit stop abutment comprising at least one region of at least one movable element arranged in an at least one seat of said propeller cylindrical casing for the modification of the position of said limit stop abutment of said at least one non-zero interval (?),
wherein said at least one movable element is at least partially threaded and installed in said at least one seat comprising at least one threaded portion the region of the movable element acting as at least one limit stop abutment of said at least one angular interval (?) comprises at least the end of said at least one movable element, the rotation with the consequent axial displacement of said threaded movable element in said at least one threaded seat modifying the position of said limit stop abutment of said at least one non-zero angular interval (?),
said hub further comprising adjustment means for adjusting the position of said at least one movable element, in one or more discrete intervals, for modifying the position of said at least one limit stop abutment of said at least one non-zero angular interval (?),
wherein said adjustment means of the position in one or more discrete intervals of said at least one movable element comprises two or more grooves provided on at least part of the surface of said at least one movable element spaced from each other by one or more angular intervals (?) for the definition of said one or more discrete intervals of position adjustment of said at least one movable element,
wherein said adjustment means further comprises at least one block element engaging at least partially with said at least one groove of said movable element and at least partially with a seat of said propeller cylindrical casing,
wherein the two or more grooves spaced from each other by one or more angular intervals (?) provides a division of the rotation and of the axial displacement of the movable element, with a correspondent subdivision of the obtained fluid dynamic pitch values as a function of the movable element displacement, the rotation of the movable element of one or more intervals (?) with the arrangement of a predetermined groove in correspondence with the block element provides a predetermined modification of the fluid-dynamic pitch.

US Pat. No. 10,336,415

WATERCRAFT LIFT SYSTEM AND METHOD

Autolift, LLC, Walker, M...

1. A watercraft lift system for placement in a body of water, comprising:a cradle assembly including longitudinally-extending first and second cradle rails, the cradle rails oriented substantially parallel to one another; and
at least one side guide longitudinally-extending in a direction substantially parallel to the first and second cradle rails and connected to the cradle assembly such that the first cradle rail and the at least one side guide move together,
wherein both the first cradle rail and the at least one side guide are movable in a lateral direction, which is generally parallel to a surface of the body of water and generally perpendicular to the direction of their longitudinal extensions, between a watercraft-receiving position and a watercraft-received position when a watercraft is positioned within the watercraft lift system's confines.

US Pat. No. 10,336,413

KITE CONTROL BAR WITH INTEGRATED LINE ADJUSTMENT MEANS

OCEAN RODEO SPORTS INC., ...

1. A kite control bar comprising:a control bar body having a line guide along an exterior surface of the control bar with a fixed pawl towards one end;
a reel pivotally mounted towards the one end of the control bar body, the reel having a shaft with a knob on the shaft to enable manual rotation of the reel, the reel having a ratchet gear, the reel being pivotally movable from an engaged position in which the ratchet gear of the reel is engaged with the pawl on the control bar body thereby preventing rotation of the reel and a disengaged position in which the ratchet gear of the reel is disengaged from the pawl on the control bar body thereby allowing rotation of the reel;
and at least one control line passing along the line guide of the control bar body and engaged with the reel, the reel being biased into the engaged position, the reel being moved from the engaged position to the disengaged position by pushing the knob away from a center of the control bar body.

US Pat. No. 10,336,399

STEERING ASSEMBLY FOR A MOTORCYCLE HAVING A CONTINUOUSLY VARIABLE TRANSMISSION

Radial Engine Innovations...

1. A motorcycle comprising:a motorcycle frame;
at least two ground-engaging wheels operatively connected to the motorcycle frame; wherein the at least two ground-engaging wheels are a hubless configuration;
a steering assembly comprising:
handlebars;
an upper steering stem;
a lower steering stem; and
a lever assembly intermediate the upper steering stem and the lower steering stem;
wherein the steering assembly is operably connected to a front ground-engaging wheel.

US Pat. No. 10,336,388

FOLDABLE FENDER FOR A MOTOR VEHICLE

Bayerische Motoren Werke ...

1. A fender for a motor vehicle, comprising:a first fender section and a second fender section; and
two pin-shaped connection elements,
wherein
the second fender section is rotatably connected to the first fender section so as to be able to rotate at least between an operational position and an open position,
the rotatable connection between the second fender section and the first fender section is provided by the two pin-shaped connection elements, and
the second fender section overlaps a support portion of the first fender section extending away from a rotation axis between the two pin-shaped connection elements toward the second fender section.

US Pat. No. 10,336,383

COMPONENT FOR A VEHICLE

Bayerische Motoren Werke ...

1. A vehicle component, comprising:a vehicle body component, wherein
the vehicle body component has at least one test portion arranged in a predetermined region of the vehicle body component,
the at least one test portion is connected integrally to the vehicle body component via at least one connecting element extending in a first direction between the at least one test portion and the vehicle body component, and
the at least one connecting element is configured as a predetermined breaking point having substantially equal dimensions in directions orthogonal to the first direction.

US Pat. No. 10,336,365

ELECTROMECHANICAL POWER STEERING SYSTEM

THYSSENKRUPP PRESTA AG, ...

1. An electromechanical power steering system for a motor vehicle comprising:an electric motor having a stator that is fitted with at least two electrical winding sets, the electric motor having a rotor that is fitted with permanent magnets, wherein the electric motor assists with steering by exerting a steering movement, which is introduced into an input means by a driver, on the motor vehicle;
a main control unit that comprises a basic controller and that determines a motor current prespecification, which is configured to be output to the at least two electrical winding sets, from a prespecified steering value based on the steering movement that is introduced by the driver;
a power control unit that provides and feeds the motor current prespecification, which the main control unit determines, to the at least two electrical winding sets;
a driver control system for each of the at least two electrical winding sets, wherein the driver control systems and the basic controller of the main control unit each include a microcontroller and are combined to form an assembly; and
a power driver for each of the at least two electrical winding sets, wherein each power driver is connected to one of the driver control systems, wherein at least two of the power drivers are disposed in the power control unit and are configured as half-bridges with power semiconductor switches,
wherein the microcontrollers of the basic controller and the driver control systems form a redundant system with respect to a failure of at least one of the microcontrollers.

US Pat. No. 10,336,353

WORKER PROTECTION SYSTEM

METROM RAIL, LLC, Crysta...

1. A system for worker protection, the system comprises:a wayside detection unit, configured for placement on or near path of a vehicle, the wayside detection unit comprising:
a housing for enclosing components of the wayside detection unit;
a support structure for holding and supporting the wayside detection unit when placed on or near the path;
a power supply for powering components of the wayside detection unit;
one or more sensory components, for detecting, monitoring, and/or tracking vehicles;
a communication component, comprising one or more antennas, configured for transmitting and/or receiving wireless signals; and
one or more circuits operable to:
process signals and data, and
perform one or more applications or functions relating to operations of the wayside detection unit;
wherein the wayside detection unit is configured to communicate signals and/or messages to one or more companion alert devices while providing monitoring and tracking services in a work site.

US Pat. No. 10,336,348

BRACKET

Perpetuum Ltd., Southamp...

1. A bracket for mounting external equipment to the underside of rolling stock, the bracket comprising first and second plates, a first set of apertures formed in at least one of the first and second plates for attachment of external equipment to the bracket and a second set of apertures formed in at least one of the first and second plates for attachment of the bracket to the underside of rolling stock, or to a component or system adapted to be mounted to the underside of rolling stock and the bracket further comprising at least one joining member disposed between the first and second plates; wherein the joining member(s) are joined to the first plate by a plurality of joints and joined to the second plate by a plurality of joints, wherein the joining member or at least one of the joining members is substantially planar, or includes at least one substantially planar portion.

US Pat. No. 10,336,329

SADDLED VEHICLE

Kabushiki Kaisha F.C.C., ...

1. A saddled vehicle configured to be driven by a driver sitting on a saddle seat of the vehicle while steering the vehicle with a handlebar comprising:a handlebar comprising first and second ends, a grasping grip provided on the first end and configured to be grasped by a driver, and a throttle grip provided in the second end and configured for an accelerator operation;
first and second brake operation means for performing braking operations of a front wheel and a rear wheel, each having a different braking operation target;
a cruise controller configured to perform automatic travel control of the vehicle by controlling the travel of the vehicle to a control degree; and
a cruise control adjustment means for controlling the control degree wherein the cruise control adjustment means changes the control degree in accordance with operation conditions of the first brake operation means and the second brake operation means.

US Pat. No. 10,336,305

ASPIRATORS FOR PRODUCING VACUUM USING THE VENTURI EFFECT

Dayco IP Holdings, LLC, ...

1. A Venturi device for producing vacuum from fluids in an engine system comprising:a body defining a Venturi gap separating apart an outlet end of a converging motive section and an inlet end of a diverging discharge section by a lineal distance, wherein the converging motive section defines an inner passageway that tapers as a hyperbolic function from a circular-shaped motive inlet to an elliptical- or polygonal-shaped motive outlet and the diverging discharge section gradually, continuously tapers toward the Venturi gap; and
a suction port in fluid communication with the Venturi gap;
wherein the diverging discharge section defines an elliptical- or polygonal-shaped discharge inlet;
wherein the hyperbolic function provides flow lines at the motive outlet end being parallel to one another.

US Pat. No. 10,336,299

BRUSHLESS WIPER MOTOR

Mitsuba Corporation, Kir...

1. A brushless wiper motor which swings a wiper, comprising:a housing which rotatably supporting an output shaft;
a motor housing unit attached to the housing;
a stator housed in the motor housing unit;
a rotor disposed inside the stator, the rotor rotating the output shaft; and
a pressing claw formed on an outer periphery of the stator, the pressing claw being pressed against an inner periphery of the motor housing unit to fix the stator to the motor housing unit, a tip end portion of the pressing claw being provided with a press-fitting projection projecting in an outward direction of the stator, wherein
a base end portion of the pressing claw is connected to the outer periphery of the stator,
a tip end portion of the pressing claw serves as a free end and is directed in a circumferential direction of the stator,
the stator is press-fitted in the housing with the press-fitting projection pressed against an inner face of the housing.

US Pat. No. 10,336,282

SELF-CONFORMING REARSEAT AIR BAG

TRW VEHICLE SAFETY SYSTEM...

3. An apparatus for helping to protect a rear seat occupant of a vehicle, the apparatus comprising an airbag having a stored condition in a housing mounted to or within a seatback of a vehicle seat positioned in front of the rear seat occupant, the airbag comprising one or more panels of material interconnected to define an inflatable volume and having a substantially U-shaped configuration when viewed from the side, wherein the airbag includes a first portion that forms one leg of the U-shaped airbag, a second portion that forms another leg of the U-shaped airbag, and a third portion that interconnects the first and second portions, the airbag being configured so that when inflated its U-shaped configuration is inverted such that the third portion forms a top portion of the airbag.

US Pat. No. 10,336,273

SENSOR SYSTEM FOR DETECTING THE ADJUSTMENT POSITION OF A VEHICLE SEAT

POLYRESEARCH AG, Chur (C...

1. A sensor system for detecting the adjustment position of a vehicle seat, by which a relative adjustment of an at least partially ferritic upper rail, moveable lengthwise along a longitudinal extension of an at least partially ferritic stationary lower rail, at least in two adjustment positions, namely a forward adjustment position and a rearward adjustment position, will be detected, the sensor system comprising:a Hall sensor, and a first preloaded magnet, free of flux concentrators and shielding sheets, whereby the Hall sensor and the first preloaded magnet are arranged along a longitudinal extension of the upper rail that is moveable lengthwise in such a way that during an adjustment of the upper rail relative to the stationary lower rail, passage of a free longitudinal end of the lower rail will be monitored and will result in a change of an output signal of the Hall sensor corresponding to a change from the forward adjustment position to the rearward adjustment position of the vehicle seat and vice versa, the sensor system being configured in such a way that in the unmounted state, and output signal corresponding to a reatward adjustment position of the vehicle seat will be generated at the Hall sensor.

US Pat. No. 10,336,256

REDUCTION OF LED HEADLIGHT FLICKERING IN ELECTRONIC MIRROR APPLICATIONS

Ambarella, Inc., Santa C...

1. An apparatus comprising:a sensor configured to generate a first video signal; and
a processor configured to (A) search for a flickering effect in a frame of said first video signal, (B) determine a location and a region of pixels to modify within said frame in response to said flickering effect, (C) determine a modification based on said flickering effect in said frame, (D) perform said modification of said region of pixels in said first video signal by determining average values of pixels based on said location of said region of pixels over consecutive frames of said first video signal and (E) generate a second video signal in response to (i) said modification of said region of pixels and (ii) said first video signal, wherein said second video signal masks said flickering effect by modifying pixels of said region of said second video signal when viewing said second video signal on a display.

US Pat. No. 10,336,246

INTEGRALLY LIGHTED TOW BAR

Roadmaster, Inc., Vancou...

1. A tow bar assembly, comprising:an outer tow arm having a proximal end and a distal end,
wherein the proximal end of the outer tow arm is configured to attach to a linkage,
wherein the linkage is configured to attach to a towing vehicle;
an inner tow arm having a proximal end of the inner tow arm and a distal end of the inner tow arm,
wherein the proximal end of the inner tow arm is telescopically disposed within the outer tow arm at the distal end of the outer tow arm,
wherein the distal end of the inner tow arm is configured to attach to a load;
an exterior channel spanning a length of the outer tow arm on at least one side; and
a light strip disposed within the exterior channel comprising lighting elements,
wherein the lighting elements illuminate indicative of a mode of operation of the towing vehicle.

US Pat. No. 10,336,244

ARRANGEMENT AND METHOD FOR PRODUCING AN ASYMMETRICAL, GLARE-FREE HIGH-BEAM

Varroc Lighting Systems, ...

1. An arrangement for generating a glare-free high-beam for vehicle headlights comprising,a plurality of LEDs controllable by an Adaptive Driving Beam (ADB) control and regulating unit,
a front camera connected with the ADB control and regulating unit and configured to transmit information about oncoming and/or preceding vehicles to the ADB control and regulating unit,
wherein the vehicle headlights are configured for generating an asymmetric ADB illumination area only for an area of an own lane and wherein for an area of an oncoming lane, the headlights generate only a low-beam area and a high-beam area, and
wherein the number of LEDs in the headlights for the area of the oncoming lane to be illuminated is reduced to one half compared to the number of LEDs for the areas to be illuminated for the own lane.

US Pat. No. 10,336,241

SCREW-DRIVING BIDIRECTIONAL ADJUSTMENT MECHANISM FOR ADJUSTING RELATIVE POSITION OF HIGH AND LOW BEAM SHAPES OF AUTOMOBILE LAMP

SHANGHAI KOITO AUTOMOTIVE...

1. A screw-driving bidirectional adjustment mechanism for adjusting the relative position of the high and low beam shapes of an automobile lamp, said bidirectional adjustment mechanism comprising:an open box-shaped sliding groove (8) fixedly connected with a low beam assembly unit (9) and a high beam assembly unit (10) which is rotationally fitted with the low beam assembly unit (9), has one end capable of being moved through a shift lever (7), and is connected to a sliding block assembly,
characterized in that,
the open box-shaped sliding groove (8) is internally provided with a sliding block assembly which is capable of respectively sliding in the open box-shaped sliding groove (8) in the directions vertical to each other;
the sliding block assembly comprises:
a sliding block (1) formed with a cavity therein,
and a gear (2) disposed in the cavity;
an upper edge in the inner cavity of the sliding block (1) is formed with a rack structure (1a) meshed with the gear (2);
a through-hole for bearing a shift lever head (7a) of a high beam assembly (10) is formed at the middle portion of the gear (2); the gear (2) is capable of rolling in a length direction of the rack structure (1a), in the cavity of the sliding block (1) along the rack structure (1a);
on the other side, meshed with the rack structure (1a) of the gear (2), the gear (2) is meshed with an adjusting screw (3) which is disposed along the length direction of the rack structure (1a);
the adjusting screw (3) is capable of rotating along the axial direction thereof;
in this way, by such meshing relationship, by rotating the adjusting screw (3) forward or backward, the gear (2) is capable of being driven to roll along the rack structure (1a); meanwhile, when the shift lever head (7a) of a shift lever (7) which is embedded into the through-hole in the middle portion of the gear (2) and connects the high beam assembly (10) is shifted to move along the length direction of the rack structure (1a), the high beam assembly (10) is driven to swing around a pivot point (9a) along the horizontal direction.

US Pat. No. 10,336,238

TRUCK BED REAR CARGO TIE DOWN ENGAGEMENT STRUCTURE

1. A load securement apparatus for a vehicle incorporating a cargo bed and a tailgate movable between a raised configuration and a lowered configuration to close and open the cargo bed, the load securement apparatus comprising at least one tie-down engagement structure connected to the vehicle and positioned so as to be engageable with a tie-down member by inserting a portion of the tie-down member into a gap formed between an end of the cargo bed and the tailgate after the tailgate has been lowered to the lowered configuration, the load securement apparatus further comprising a rail structure attached to the vehicle, and wherein the at least one tie-down engagement structure is movably connected to the rail structure so as to be movable to, and securable in, a position of a plurality of positions along the rail structure prior to the tie down member being engaged with the at least one tie-down engagement structure.

US Pat. No. 10,336,228

FOUR-COMPONENT ARMREST ASSEMBLY AND METHOD OF MANUFACTURING SAME

Ford Global Technologies ...

1. An armrest subassembly, comprising:a support substrate including a receiver defined within an upstanding upper lip;
a fabric layer stretching across said receiver; and
a matrix interface connecting said fabric layer to said support substrate, wherein said matrix interface includes a portion of said fabric layer impregnated with resin of said support substrate.

US Pat. No. 10,336,217

SEAT LIFTER AND GEAR MECHANISM

Delta Kogyo Co., Ltd., H...

5. A gear mechanism comprising a first gear and a second gear that mesh with each other in a state in which axial directions thereof are parallel to each other, whereineach tooth of one gear of the first and second gears has such a shape that a tooth thickness and a tooth depth dimension of each of the teeth gradually decreases from one end toward the other end in the axial direction, the tooth depth dimension being a dimension from a tooth root to a tooth tip of the respective tooth in a radial direction of the one gear,
each tooth of the other gear of the first and second gears has a constant thickness over an entirety of the other gear in the axial direction, and
the teeth of the first gear and the teeth of the second gear mesh with each other by approaching each other in the axial direction.

US Pat. No. 10,336,185

FINAL DRIVE FOR A ROAD VEHICLE

BorgWarner Sweden AB, La...

1. A final drive for a road vehicle, comprising a pinion gear on a pinion axle journaled in a housing, the pinion gear being in gear engagement with a crown gear journaled for rotation transversely to the pinion axle, the final drive comprisingan all wheel drive (AWD) coupling, comprising a disc package axially controlled by a hydraulic piston for optionally transmitting torque from an ingoing axle to the pinion axle and a means for rotatably connecting the disc package to the pinion axle,
the ingoing axle of the AWD coupling being radially journaled only by the pinion axle.

US Pat. No. 10,336,168

APPARATUS FOR COVERING A CONTAINER LOAD

TY-CROP MANUFACTURING LTD...

1. An apparatus for covering an open top of a transportation trailer container, the apparatus comprising:an arm pivotable between a closed position and an open position, the arm holding a rotatable roller for dispensing and receiving a flexible cover, the flexible cover being wrapped around the roller when the arm is in the open position, the flexible cover being unrolled from the roller to cover the open top due to motion of the arm from the open position to the closed position, the arm pivotably mounted to an arm pivot;
a recessed region comprising the arm pivot; and
a secondary cover movable between a cover closed position and a cover open position, the secondary cover covering a top of the recessed region when in the cover closed position, the secondary cover biased toward the cover closed position, the secondary cover being overtop of the arm when the arm is in the closed position and the secondary cover is in the cover closed position.

US Pat. No. 10,336,166

DOOR IMPACT BEAM AND MANUFACTURING METHOD THEREOF

Hyundai Motor Company, S...

1. A method of manufacturing a door impact beam that is disposed on a door frame of a vehicle, the method comprising:preparing a raw pipe having a circular cross-section with first and second end portions open;
forming a secondary pipe having a larger diameter at first and second end portions than at a center portion by expanding the first and second end portions of the raw pipe by inserting a punch into the first and second end portions of the raw pipe; and
pressing the secondary pipe to make the first and second end portions of the secondary pipe flat and make the center portion of the secondary pipe concaved in a predetermine direction.

US Pat. No. 10,336,159

REFRIGERATION

DEARMAN ENGINE COMPANY LT...

1. A system comprising:a cryogenic engine system comprising:
an output shaft;
a first expander utilizing a working fluid and heat exchange fluid within the first expander;
a circuit comprising an introducer, the introducer providing said heat exchange fluid into the first expander and wherein the first expander is configured to cause expansion of said working fluid within the first expander such as to produce shaft power;
a refrigeration system, including a heat exchange system wherein:
the cryogenic engine system and the refrigeration system are thermally coupled with each other via the heat exchange system such that the working fluid or heat exchange fluid in the cryogenic engine system acts as a heat sink for removing heat from the refrigeration system and heat generated by the refrigeration system is used to expand the working fluid in the cryogenic engine system;
a refrigeration compartment thermally connected to the heat exchange system;
wherein the cryogenic engine system is a direct and an indirect heat sink for removing heat from the refrigeration compartment; and
wherein the heat exchange system comprises:
a first heat transfer member in direct thermal contact with the working fluid from the cryogenic engine system and in direct thermal contact with the refrigeration compartment;
a second heat transfer member in direct thermal contact with expanded working fluid and the heat exchange fluid of the cryogenic engine system;
a third heat transfer member in direct thermal contact with an interior of the refrigeration compartment; and
an intermediate heat transfer fluid circulation system in thermal contact with both the second heat transfer member and the third heat transfer member.

US Pat. No. 10,336,146

REMOVABLE SECURING CHAIN ATTACHMENT ASSEMBLY

HORIZON GLOBAL AMERICAS I...

1. A securing member comprising:a securing body capable of securing an accessory;
an insert body extending from the securing body and capable of being inserted into a receiver of an under bed hitch mounting device;
a locking member positioned in the insert body;
a camming mechanism extending above the insert body, the camming mechanism in operative communication with the locking member, wherein actuation of the camming mechanism positions the locking member from an unlocked position to a locked position.

US Pat. No. 10,336,132

WHEEL OF A MOTOR VEHICLE WITH A SPOKE AREA COVER

Bayerische Motoren Werke ...

1. A wheel of a motor vehicle, comprising:a hub portion;
spokes extending radially outward from the hub portion;
a rim supported on the spokes;
an interior-side spoke area cover facing an interior side of the spokes;
an exterior-side spoke area cover delimited by the rim facing an exterior side of the spokes; and
at least one over pressure-controlled and/or under pressure-controlled ventilation opening, the at least one ventilation opening being arranged to automatically ventilate a spoke area between the interior and exterior-side covers that is closed from the environment.

US Pat. No. 10,336,130

DRY-ERASE BOARD WITH INSERTS

Chameleon Corporation, In...

1. A dry-erase board comprising:a rigid base member, the rigid base member having a periphery;
a frame attached to at least a portion of the rigid base member, at least a portion of the frame being rotatable relative to the rigid base member; and
a cover disposed between the rigid base member and the frame, the cover movable relative to the rigid base member and having an erasable surface suitable for use with a writing instrument, and wherein the frame covers at least a portion of the periphery of rigid base member and at least a portion of a periphery of the cover.

US Pat. No. 10,336,124

SECURITY ELEMENT COMPRISING AN INTERFERENCE PIGMENT AND A NANOMETRIC FILLER

OBERTHUR FIDUCIAIRE SAS, ...

1. A security element for a secured document, comprising:a security structure comprising an opaque layer and at least one opening in this opaque layer; and
a masking structure superposed at least partially on the security structure, for decreasing visibility of the security element in reflected light, the security element being present within the secured document or on a surface of the secured document, the masking structure comprising a nanoscale filler and a multilayer interferential pigment, the security element being visible under transmitted light through the masking structure.

US Pat. No. 10,336,094

INKJET PRINTER

ROLAND DG CORPORATION, S...

1. An inkjet printer, comprising:a first ink head including a plurality of nozzles through which a first ink is ejected towards a recording medium to form ink dots of the first ink on the recording medium;
a second ink head including a plurality of nozzles through which a second ink is ejected towards the recording medium to form ink dots of the second ink on the recording medium;
a moving mechanism to move the first ink head and the second ink head, and the recording medium, with respect to each other; and
a controller connected with the first ink head, the second ink head and the moving mechanism, to control the first ink head, the second ink head and the moving mechanism;whereinthe controller includes:
a converter to convert image data of the first ink into the ink dots of the first ink, and to convert image data of the second ink into the ink dots of the second ink;
a generator to generate, upon receipt of data on the ink dots of the second ink converted by the converter, a plurality of dot groups, including at least a first dot group and a second dot group, of the ink dots of the second ink, the first dot group including at least a portion of the ink dots of the second ink, and the second dot group including at least a portion of the ink dots of the second ink;
a first printing controller to form, on the recording medium, a first printing layer of the ink dots of the first ink and the ink dots of the first dot group; and
a second printing controller to form a second printing layer of the ink dots of the second dot group, above or below the first printing layer; and
the generator generates the plurality of dot groups such that the plurality of dot groups include all the ink dots of the second ink;
the first ink is a special color ink; and
the second ink is a process color ink.

US Pat. No. 10,336,047

METHOD OF PREVENTING CORROSION OF MATING SURFACES OF COMPONENTS

MAHINDRA AND MAHINDRA LIM...

1. A method of preventing corrosion of the mating surfaces of components, said method comprising:(i) impregnating a polyester based carrier with at least one anaerobic acrylic adhesive to form an impregnated carrier;
(ii) spraying at least one pressure sensitive acrylic adhesive on one surface of said impregnated carrier to form an impregnated carrier having a pressure sensitive acrylic adhesive layer;
(iii) protecting said pressure sensitive acrylic adhesive layer using a protective silicon release liner to configure a pasting surface on said impregnated carrier;
(iv) pasting said pasting surface after detaching said silicon release liner therefrom on a first component, wherein said pasting surface is in contact with said first component;
(v) abutting a second component to said first component such that said impregnated carrier is sandwiched therebetween; and
(vi) applying force on said abutted first and second components such that said anaerobic acrylic adhesive oozes out from said impregnated carrier and coats mating surfaces of said abutted first and second components in the absence of oxygen to commence and complete curing of said anaerobic acrylic adhesive on mating surfaces of said first and said second components.

US Pat. No. 10,336,008

METHOD FOR AUTOMATIC CALIBRATION OF A DEVICE FOR GENERATIVE PRODUCTION OF A THREE-DIMENSIONAL OBJECT

EOS GMBH ELECTRO OPTICAL ...

1. A method for automatically calibrating an apparatus for generatively producing a three-dimensional object, comprising:providing a construction zone, in which the object is to be constructed layer by layer by selective consolidation of a pulverulent material;
providing a control unit for controlling the apparatus,
providing an irradiation device for emitting electromagnetic radiation onto selective regions of an applied layer of the material, wherein the irradiation device comprises at least one first and at least one second scanner;
operating the irradiation device with the first scanner, irradiating a first scan zone in the construction zone, and the second scanner irradiating a second scan zone in the construction zone; and
irradiating the applied layer of the material or a target by means of the first scanner in order to produce a first test pattern in the material or the target;
irradiating the applied layer of the material or the target by means of the second scanner in order to produce a second test pattern in the material or the target;
detecting the first and second test patterns by means of a camera and assigning the first and second test patterns to the first and second scanners, respectively;
comparing the first and second test patterns with one another;
determining a relative deviation between the first test pattern and the second test pattern comprising at least a deviation of a lattice constant of the test patterns, a deviation of a position of the test patterns in a coordinate system, a deviation of an orientation of the test patterns in the coordinate system or a deviation of size of the test patterns; and
calibrating the first and/or the second scanner in such a way that the relative deviation between the first test pattern and the second test pattern falls below a predetermined setpoint value.

US Pat. No. 10,335,935

TORQUE WRENCH WITH SHOCK ABSORPTION

Snap-on Incorporated, Ke...

1. A tool having a handle portion and a drive head, the tool comprising:a control housing extending from the drive head and including first and second housing portions;
a controller disposed in the control housing;
a display disposed between the first housing portion and the controller, the display having opposing first and second surfaces, the first surface facing the first housing portion and the second surface facing the controller and the second housing portion; and
first and second materials adapted to absorb impact forces to protect the display when the tool experiences an impact force, the first material is disposed between the second surface and the controller, and the second material is disposed between the first surface and the first housing portion;
a battery tray disposed in the handle portion;
an end cap coupled to an end of the battery tray;
a flange disposed in the handle portion and
a third material disposed between the end of the battery tray and the flange, wherein the end cap and the battery tray are adapted to slide within the handle portion and the third material is adapted to compress upon application of an impact force to the end cap.

US Pat. No. 10,335,910

SEALING MEMBER FOR MACHINE TOOLS

BANDO CHEMICAL INDUSTRIES...

1. A wiper member for machine tools comprising:a supporting member;
a plate-shaped elastic member; and
an adhesive layer which bonds the elastic member to the supporting member, wherein
the supporting member has a shape of a bent plate-like body, and comprises a supporting portion and a first protective portion,
the elastic member is bonded to the supporting portion via the adhesive layer laminated on a part of a front face of the elastic member so as to be curved along the bent shape of the supporting member,
a first corner portion formed by a back face and one side face of the elastic member is assumed to be an edge portion in contact with an opposite material, and the one side face is formed by cutting,
a part of the front face of the elastic member at the side of an edge portion on which the adhesive layer is not laminated is in contact with an inner face of the first protective portion of the supporting member; and
a second protective portion, and the second protective portion is provided at a distal end of the supporting member on a side opposite to the supporting portion.

US Pat. No. 10,335,908

ROTARY TABLE DEVICE

TSUDAKOMA KOGYO KABUSHIKI...

1. A rotary table device for a machine tool comprising:a main shaft that is rotatably supported with respect to a frame by a first bearing in an insertion hole formed in the frame;
a table that is secured to an end side of the main shaft, and on which a workpiece, which serves as an object to be processed, is mounted; and
a clamp piston that is provided so as to be movable in an axial direction of the main shaft in the insertion hole,
wherein the main shaft has a clamp surface that faces the table,
wherein a pressure chamber is defined by the frame and the clamp piston,
wherein the table is brought into a clamped state by friction force that is generated between the clamp piston and the clamp surface by causing the clamp piston to press-contact the clamp surface when an operating fluid is supplied to the pressure chamber,
wherein the rotary table device further comprises a second bearing that is provided separately from the first bearing, the second bearing being provided between the table and the frame so as to contact the table and the frame, and being provided so as to directly support the table with respect to the frame, and
wherein at least part of the second bearing is provided so as to be positioned within a range of existence of the pressure chamber in a radial direction of the main shaft.

US Pat. No. 10,335,880

RACKS FOR HIGH-TEMPERATURE METAL PROCESSING

H.C. STARCK INC., Newton...

1. An apparatus for receiving and supporting one or more components during processing thereof at a process temperature greater than approximately 1000° C., the apparatus comprising:a first shelf (i) comprising a first refractory metal having a melting point greater than the process temperature and (ii) defining therethrough a plurality of apertures, each aperture being threaded through at least a portion of its thickness;
a plurality of first support posts, each first support post (i) comprising a second refractory metal having a melting point greater than the process temperature, (ii) having a threaded lower end for engagement with a threaded aperture of the first shelf, and (iii) defining a support collar proximate an upper end opposite the threaded lower end, a lateral dimension of the first support post above the support collar being smaller than a lateral dimension of the first support post below the support collar;
a second shelf (i) comprising a third refractory metal having a melting point greater than the process temperature and (ii) defining therethrough a plurality of apertures, each aperture of the second shelf being configured to receive the upper end of one of the first support posts such that a portion of the second shelf proximate each aperture thereof rests upon the support collar of the first support post received in the aperture,
a third shelf (i) comprising a fourth refractory metal having a melting point greater than the process temperature and (ii) defining therethrough a plurality of apertures; and
a plurality of second support posts, each second support post (i) comprising a fifth refractory metal having a melting point greater than the process temperature, (ii) having a threaded lower end for engagement with a threaded aperture, (iii) defining a support collar proximate an upper end opposite the threaded lower end, a lateral dimension of each second support post above the support collar being smaller than a lateral dimension of each second support post below the support collar, and (iv) defining a dowel pin mount through the upper end thereof above the support collar,
wherein (A) the upper end of each second support post is receivable within an aperture of the third shelf such that (i) a portion of the third shelf proximate each aperture thereof rests upon the support collar of the second support post received in the aperture, and (ii) the dowel pin mount of each second support post is disposed above a top surface of the third shelf, (B) each of the apertures of the second shelf is threaded through at least a portion of its thickness, and (C) the threaded lower end of each second support post is receivable within one of the threaded apertures in the second shelf.

US Pat. No. 10,335,840

PRODUCTION LINES AND METHODS FOR HOT ROLLING STEEL STRIP

THYSSENKRUPP STEEL EUROPE...

1. A production line for hot rolling a steel strip, the production line comprising:a hot rolling line having a plurality of rolling stands, the plurality of rolling stands comprising,
a plurality of successive active rolling stands disposed at an upstream end of the hot rolling line, and
at least one inactive rolling stand disposed downstream of the plurality of active rolling stands in a conveying direction of the steel strip to be hot rolled,
the hot rolling line is configured to hot roll the steel strip by passing the steel strip successively through the plurality of rolling stands in the conveying direction; and
a cooling section configured to cool the hot rolled steel strip after exiting a last of the active rolling stands, the cooling section having an upstream end positioned to start after the last of the active rolling stands and before the at least one inactive rolling stand such that at least a portion of the cooling section is shifted to be located upstream of the at least one inactive rolling stand of the hot rolling line, the cooling section comprising at least,
a first cooling unit disposed at the upstream end of the cooling section and positioned between the last of the active rolling stands and the at least one inactive rolling stand, and
a second cooling unit disposed downstream of the at least one inactive rolling stand,
wherein the first cooling unit subjects the steel strip to cooling fluid along a length of the steel strip measured with respect to the conveying direction that is at most 25% of a distance between the last of the active rolling stands and the at least one inactive rolling stand.

US Pat. No. 10,335,747

ADHESIVE-AIR INFUSER DEVICE AND METHOD OF USING THE SAME

Simchem Inc., Chapel Hil...

1. A method of infusing air into an adhesive, the method comprising steps for:directing a flow of air through an air nozzle and into an interior of a hollow body at an upstream end of the hollow body;
directing a flow of adhesive into the interior of the hollow body and around at least a portion of the air nozzle at the upstream end of the hollow body;
causing the adhesive and the air to flow from the upstream end of the hollow body toward a downstream end of the hollow body such that the adhesive and the air mix to form an adhesive-air solution while flowing through the hollow body; and
directing the adhesive-air solution out of the interior of the hollow body at the downstream end of the hollow body,
wherein the air nozzle comprises an air diffuser defining a plurality of entry openings through which the air flows into the interior of the hollow body such that the air flows into the interior of the hollow body to form air bubbles within the adhesive flowing around the air diffuser.

US Pat. No. 10,335,745

BASE STABLE SEMIPERMEABLE MEMBRANE AND METHODS THEREOF

AMS TECHNOLOGIES INT. (20...

1. A base stable semipermeable nanofiltration (NF) membrane, wherein said NF membrane is prepared by a process comprising steps of:a. providing an ultrafiltration (UF) base support membrane selected from the group consisting of polyethersulfone (PES) and polysulfone (PS); said UF base membrane is a non-crosslinked base polymer;
b. providing a modification solution comprising water soluble partially crosslinked polyethylenimine (PEI) or non-crosslinked PEI;
c. activating the surface of said UF membrane by subjecting said UF membrane to heating in an aqueous solution containing 0.1% (w/w) of the condensate of cyanuric chloride with sulfanilic acid for 1 hour at a temperature of 70° C.;
d. forming a first crosslinked layer upon at least a portion of a surface of said UF base support membrane of step (c); said forming comprises steps of:
i. providing said modification solution to comprise 1% (w/w) water soluble partially crosslinked PEI or 1% (w/w) oligomer-polymer mixture of water soluble non-crosslinked PEI (PEI MW 800 and PEI MW 750K at a ratio of 1:1);
ii. preparing said modification solution to comprise partially crosslinked PEI by admixing an aqueous solution of said condensate of cyanuric chloride with sulfanilic acid within an aqueous solution of said PEI oligomer-polymer mixture at a ratio of said condensate to said PEI being 0.3:1.0, with subsequent heating of said modification solution at 50° C. for 3 hours;
iii. immersing said UF base support membrane in said prepared 1% (w/w) modification solution to comprise a partially crosslinked PEI, for 18 hours at a room temperature, then subsequent heat-treating said membrane in either modification solution for 1 hour at 50° C. or in prepared 1% (w/w) solution comprising oligomer-polymer mixture of non-crosslinked PEI (PEI MW 800 and PEI MW 750K at a ratio of 1:1) for 1 hour at 90° C.;
iv. after cooling and washing, contacting said UF base support membrane of step (iii) with aqueous solution comprising 0.1% w/w of the condensate of cyanuric chloride with sulfanilic acid for 1 hour at room temperature; and
v. curing said UF base support membrane of step (iv) in an alkaline solution, pH=11, for 2 hours at 70° C. to complete the formation of the first cross-linked layer upon of said activated UF base support membrane;
e. forming a second crosslinked layer upon said first layer of said UF base support membrane of step (d) comprising steps of:
i. providing a modification solution comprising water soluble partially crosslinked PEI prepared according to step (d, ii) and diluted to either concentration of 0.125% (w/w) or 0.125% (w/w) of non-crosslinked PEI, prepared from PEI, MW 750K;
ii. contacting said UF base support membrane of step (d, v) with an aqueous solution comprising 0.1% w/w of the condensate of cyanuric chloride with sulfanilic acid for 1 hour at room temperature;
iii. immersing said UF base support membrane of step (ii) in 0.125% (w/w) modification solution for 1 hour at room temperature for partially crosslinked PEI or alternatively at 90° C. for non-crosslinked PEI;
iv. heat-treatment of said UF base support membrane in alkaline solution, pH=11, for 2-3 hours at 60-90° C.;
v. cooling and rinsing said UF base support membrane with reverse osmosis (RO) water;
vi. immersing said UF membrane of step (v) in an aqueous solution comprising 0.1% w/w of the condensate of cyanuric chloride with sulfanilic acid for 1 hour at room temperature; and,
vii. heat-treating in an alkaline solution, pH=11, for 2 hours at 60° C., followed by 2 hours at 90° C. to complete the formation of the second crosslinked layer upon said UF membrane with said first crosslinked layer, said second crosslinked layer is a NF layer;
f. repeating said step (e) n times for providing NF membrane with n+1 multiple cross-linked layers upon said first layer of said UF base support membrane; n is an integer number equals to or greater than 1; and,
g. immersing said base stable semipermeable NF membrane in 20% solution of phosphoric acid in water at a temperature ranging from 70° C. to 90° C. for a period of time ranging from 18 to 24 hours.

US Pat. No. 10,335,742

ASYMMETRIC COMPOSITE MEMBRANES AND MODIFIED SUBSTRATES USED IN THEIR PREPARATION

HYDROXSYS HOLDINGS LIMITE...

1. A method of preparing an asymmetric composite membrane comprising the steps:irradiating a dispersion comprising sulfonated poly(ether ether ketone) and at least one cross-linking agent in an organic solvent to provide a dispersion of partially cross-linked sulfonated poly(ether ether ketone);
contacting one side of a sheet of microporous polyolefin wetted with a solution of a hydrophilicitizing agent in an aqueous solvent with the dispersion of partially cross-linked sulfonated poly(ether ether ketone);
irradiating the one side of the coated sheet at a wave length and an intensity for a time sufficient to adhere the cross-linked sulfonated poly(ether ether ketone) to the sheet of microporous polyolefin to provide a composite; and then
drying the composite at a temperature and time sufficient to provide the asymmetric composite membrane.

US Pat. No. 10,335,739

SPIRAL WOUND MEMBRANE ELEMENT AND METHOD FOR CLEANING SPIRAL WOUND MEMBRANE SHEET

BL TECHNOLOGIES, INC., M...

1. A spiral wound membrane element, comprising:a perforated central tube with a flow restriction at one end;
one for more membrane sleeves, each of the one or more membrane sleeves comprising two membrane sheets enclosed at two edges around a feed spacer sheet and wrapped around the central tube;
one or more permeate carrier sheets attached to the perforated central tube at a first edge opposite a second edge, wherein the one or more permeate carrier sheets and the one or more membrane sleeves are in a 1:1 ratio, respectively;
a seal on a third edge and a fourth edge of each of the one or more permeate carrier sheets, extending from the first edge to the second edge wherein the one or more membrane sleeves and each of the one or more permeate carrier sheets are wrapped in a spiral and the second edge of each of the one or more permeate carrier sheets is open and extends beyond each of the one or more membrane sleeves lying over each of the one or more permeate carrier sheets in a peripheral region of the spiral wound membrane element such that each of the one or more permeate carrier sheets is in fluid communication with the perforated central tube and the peripheral region of the spiral wound membrane element; and
an anti-telescoping device secured to each of end of the perforated central tube, the anti-telescoping device comprising a passage that communicates between the peripheral region of the spiral wound membrane element and inside of the perforated central tube.

US Pat. No. 10,335,732

CARBON SAFE VAPOR RECOVERY SYSTEM

JORDAN TECHNOLOGIES, LLC,...

11. A method for recovering volatile liquid vapor from an air-volatile liquid vapor mixture in a vapor mixture source, comprising:feeding an untreated air-volatile liquid vapor mixture from the vapor mixture source to a vapor absorption unit;
condensing and collecting volatile liquid vapor in said vapor absorption unit;
feeding an air-absorbent liquid vapor mixture from said absorption unit to an adsorption unit;
adsorbing the absorbent liquid vapor on a first bed of adsorbent in said adsorption unit;
regenerating a second bed of adsorbent in said adsorption unit with a vacuum regeneration unit; and
recycling regenerated vapors from said vacuum regeneration unit to said vapor absorption unit.

US Pat. No. 10,335,720

OPTIMIZATION OF VACUUM SYSTEM AND METHODS FOR DRYING DRILL CUTTINGS

FP Marangoni Inc., Calga...

1. A method of retro-fitting a shaker to include an air vacuum system, the air vacuum system for improving the separation of drilling fluid and drill cuttings on the shaker, the method comprising the steps of:a. installing a vacuum frame and manifold over screen support rails of a shaker;
b. installing a screen on the vacuum frame and manifold such that the vacuum frame and manifold mates with the underside of the screen; and
c. securing each of the support rails, vacuum screen and manifold and screen together for enabling a vacuum pressure to be applied to the underside of the screen;
wherein the shaker has at least two pairs of support rails and the vacuum frame and manifold is installed on a downstream pair of support rails, leaving at least one upstream pair of support rails without a vacuum frame and manifold.

US Pat. No. 10,335,715

WATER SKIMMING DEVICE AND METHOD

SW Feesaver, LLC, Greenv...

1. A skimmer for removing water from a sediment basin to a water removal system, said sediment basin having a depth, said skimmer comprising:a float portion;
a first pipe having a longitudinal axis, said first pipe being attached to and held by said float portion with said longitudinal axis in a horizontal position and at a distance below the surface of water in a sediment basin, said pipe having an orifice formed therein to admit said water from below said surface, said first pipe having a first end and an opposing second end;
a guard attached to said float portion and said first pipe, said guard fixedly positioning said float portion with respect to said first pipe and said orifice so that said orifice of said first pipe is located below said surface of said water, said guard having a continuous, vertically-extending side wall having a bottom edge defining a water flow path opening located below said orifice, said guard and said float portion surrounding said orifice upwardly from said bottom edge to thereby define a flow path into said orifice from the sediment basin to be only through said flow path opening, upwardly to said orifice, then downwardly though said orifice into said first pipe;
a second pipe having a first end and a second end;
an upper flexible coupling on said first end of said second pipe, said flexible coupling connected to said second end of said first pipe; and
a lower flexible coupling on said second end of said second pipe, said second flexible coupling being attachable to a water removal system; wherein said first pipe is attached to said float portion so that said orifice of said first pipe remains below said surface and the longitudinal axis remains below said surface by said distance, and said water flows through said orifice into said first pipe and then through said second pipe to said water removal system regardless of the elevation of said surface of water in said sediment basin.

US Pat. No. 10,335,708

SYSTEM AND METHOD TO GENERATE STEAM BY MIXING A FEED WATER STREAM WITH A HEATING MEDIUM

Cameron Solutions, Inc., ...

1. A method to generate steam from a feed water stream, the method comprising:routing the feed water stream into a liquid pool zone of a vessel, the liquid pool zone including a heating medium, the heating medium being less volatile than the feed water stream and maintained at an operating temperature determined by vaporization requirements;
pre-mixing the feed water stream and the heating medium outside of the liquid pool zone of the vessel;
vaporizing at least a portion of the feed water stream due to contact with the heating medium in the liquid pool zone;
removing a vaporized portion of the feed water stream from a vapor separation zone of the vessel as steam; and
removing solids from the liquid pool zone of the vessel.

US Pat. No. 10,335,706

COMBINED LIFTING BARN FENCING EQUIPMENT

Zhejiang Dafeng Industry ...

1. A combined lifting barn fencing equipment, comprising:a barn (1) movably mounted in a first annular groove in the periphery of a stage,
a lifting mechanism (4) that drives the barn (1) to lift up and down,
a fence (2) movably mounted in a second annular groove (11) of the barn (1), and
a hoisting mechanism that drives the fence (2) to lift up and down,
wherein the lifting mechanism is mounted at the bottom of the first annular groove, the hoisting mechanism (3) is mounted at the top of a gate above the stage, the barn (1) is mounted to a bedplate (6); the barn (1) descends to the first annular groove or rises to above of the stage driven by the lifting mechanism (4), when the barn (1) descends to the first annular groove, the upper surface of the bedplate (6) is flush with a stage surface; when not connected with the hoisting mechanism (3) for lifting, the fence (2) is retained inside the second annular groove (11), when connected with the hoisting mechanism (3) for lifting, the fence (2) is hoisted to the above of the stage.

US Pat. No. 10,335,705

VENUE TRAYS AND METHOD FOR MOVING VENUE TRAYS

Tait Towers Manufacturing...

9. An arrangement comprising:a first venue tray, the first venue tray having a close range event portion at which a live actor can make a presentation and/or a display can be shown and a home row seating section;
a second venue tray, the second venue tray having a downrange seating section;
a first periphery event portion at which a live actor can make a presentation and/or a display can be shown; and
a second periphery event portion at which a live actor can make a presentation and/or a display can be shown, the first venue tray and the second venue tray being displaceable relative to one another to a position in which audience members located on the first venue tray view a presentation or a display at the close range event portion of the first venue tray along a different sight line than audience members located on the second venue tray, the first venue tray and the second venue tray being positionable relative to one another such that audience members located on the first venue tray view a presentation or a display at the first periphery portion along the same sight line as audience members located on the second venue tray, and the first venue tray and the second venue tray being displaceable as a single unit to a location at which audience members located on the first venue tray view a presentation or a display at the second periphery event portion along the same sight line as audience members located on the second venue tray.

US Pat. No. 10,335,704

ARTICLE AND PACKAGING FOR GENERATING BUBBLES

Ogosport LLC, Brooklyn, ...

1. An article for soap bubble generation, comprising:an article having at least two flexible and planar films of liquid-resistant material sealed on at least one common edge and forming a pocket between said films; and
a distal planar web provided integrally with said article and extending distally from said sealed common edge, said distal web adapted to be dipped in bubble solution and having at least one hole adapted to form soap bubbles when said web is dipped in bubble solution and air is moved through said at least one hole,
wherein said web is formed by co-planar fusion of said at least two films at respective distal ends of said at least two films.

US Pat. No. 10,335,699

CAR TYPE MODEL

GATEWAY AUTOART LIMITED, ...

1. A car type model comprising(a) a body formed by a resin to which left and right doors are hingedly attached for opening and closing;
(b) a reinforcing member which is formed of a metal and is detachably attachable to an inside of the body; and
(c) a chassis that is detachably attachable to the reinforcing member;
wherein the body comprises left and right bottom portions disposed under the left and right doors, each of the left and right bottom portions comprising an elongate side surface;
wherein the reinforcing member comprises left and right frame portions with each comprising an elongate side surface;
wherein the respective elongate side surfaces of the left and right bottom portions of the body abut the elongate side surfaces of the left and right frame portions with the reinforcing member detachably attached to the body;
wherein the respective side surfaces of the elongate left and right frame portions collectively comprise a first set of screw holes and the elongate left and right bottom portions of the body collectively comprise a second set of screw holes, wherein the first set of screw holes and the second set of screw holes align with each other when the reinforcing member is detachably attached to the body, and wherein the respective first and second sets of screw holes are configured and arranged such that, with a plurality of screws screwed through the aligned screw holes in the respective side surfaces of the left and right body portions and the left and right frame portions, the left and right bottom portions are inhibited from flexing when the left and right doors are opened and closed.

US Pat. No. 10,335,694

METHOD AND APPARATUS FOR FASTENING OF INFLATABLE RIDE SURFACES

Whitewater West Industrie...

1. A system for connecting surfaces, comprising:a first surface portion having an extrusion with a first mating surface disposed beneath a plane extending along a top surface of the first surface portion;
a second surface portion having a receptacle with a second mating surface disposed beneath the plane extending along the top surface of the first surface portion, the receptacle configured to receive at least a portion of the extrusion, the first mating surface and the second mating surface configured to mate together, defining a gap therebetween, when the extrusion is at least partially received by the receptacle for connecting the first surface portion with the second surface portion; and
a flap configured to extend over the gap above the plane, and over at least a part of the first surface portion or the second surface portion, when the first mating surface is mated with the second mating surface, such that the flap is urged to lay against the first and second portions during operation when presented with a flow of water.

US Pat. No. 10,335,693

UNIVERSAL CONTROLLER HOLSTER

Integr8ted Minds Inc., M...

1. A universal controller holster comprising:a first element comprising:
two collars;
an arm connecting the two collars;
a spine extending from the center of arm; and
an angled tooth disposed at the end of the spine distal from the arm; and
a second element comprising:
a mount, the mount comprising a plurality of detents substantially to one end of the mount, each detent having an opening on the side of the mount proximal to the spine that is smaller in size than the angled tooth;
an angled support arm extending from the end of the mount distal from the detents;
a lip extending at an angle from the angled support arm;
a pass-through conduit disposed on the top of the angled support arm; and
a clip extending from the mount,wherein the angled tooth of the first element releasably mates with one of the detents of the mount to attach the spine to the mount,wherein the lip extends downward from the angled support arm toward the first element.

US Pat. No. 10,335,687

SYSTEM AND METHOD FOR PROCESSING VIRTUAL OBJECTS IN A COMPUTING ENVIRONMENT

9LOGIC TECHNOLOGIES, Red...

1. A gaming system comprising:an input device;
a display device;
a processor; and
a memory device storing instructions, which when executed by the processor, cause the processor, in conjunction with the input device and the display device, to:
initiate and execute a game that includes at least a first portion of the game and an uber hunt of the game;
generate user navigating locations associated with real-time locations;
dynamically generate virtual objects;
hide the virtual objects at the user navigating locations associated with the real-time locations;
generate virtual game objects;
enable a user to collect, using the virtual game objects, the hidden virtual objects;
offer a plurality of virtual rewards to the user based on the collection of the virtual game objects;
initiate and execute the uber hunt in response to the selection of a displayed icon;
generate and display a plurality of interactive queries using the plurality of virtual rewards for participating in the uber hunt;
generate and display clues for solving the plurality of interactive queries based on the virtual rewards;
enable the user to solve the plurality of interactive queries;
generate an uber virtual object searching game object;
generate an uber virtual object located within the user navigating locations associated with the real-time locations;
enable the user to use the uber virtual object searching game object to search for and collect the uber virtual object located within the user navigating locations associated with the real-time locations;
in response to the user collecting the uber virtual object, provide a higher level reward;
generate and display a leader board that provides distances covered by the user, coins collected by the user, and prizes collected by the user;
multiply the virtual objects on the user navigating virtual locations;
lock the virtual objects on the user navigating virtual locations;
print user initials on the virtual objects, wherein other users are enabled to view the user initials;
prevent the user on the user navigating virtual locations from seeing objections;
apply a crystal balls applying object on the user navigating virtual locations to enable the user to see any virtual objects with a radius of the user navigating virtual locations of a current position of the user;
apply a parrot object configured to fetch at least one of the virtual objects which is distant from the user, and bring the fetched at least one virtual object to a location of the user;
generate virtual hoardings;
publish advertisements on the virtual hoardings at the user navigating virtual locations; and
increase values of the virtual objects and the uber virtual object based on the published advertisements.

US Pat. No. 10,335,678

GAME PROGRAM AND INFORMATION PROCESSING DEVICE

DENA CO., LTD., Tokyo (J...

1. A non-transitory computer readable medium having machine-executable instructions with which a computer having a storage and a hardware processor, for providing a service, said machine-executable instructions comprising:a screen generation process that generates a game screen having disposed thereon multiple selectable objects that a player is allowed to select;
an acceptance process that accepts selection operation input on said selectable objects at the moment when a pointing location initially arrives at the location of a selectable object disposed on the game screen while the movement of said pointing location on the game screen is maintained by the player's operations, and said acceptance process accepts the selection operation input in a sequential manner, starting with the selectable object at which the pointing location arrives the earliest;
a special effect generation process that generates special effects in the course of a game driven by the player's operations based on at least one of the moment when the pointing location initially arrives at the location of the selectable object, or the order in which the selection operation input on the selectable objects is accepted;
a counting process that starts counting standby time associated with each of the selectable objects in the order of acceptance of the selection operation input, and
an action control process that establishes control over the actions of controlled objects associated with each of the selectable objects upon the elapse of the respective standby time, and
the special effect generation process
determines whether nor not a time difference between an earlier action of a controlled object associated with a certain selectable object and a later action of a controlled object associated with another selectable object is within a predetermined period of time and
generates special effects in the course of a game driven by the player's operations if it is determined to be within the predetermined period of time;
wherein the screen generation process generates a game screen including a control area where the multiple selectable objects are disposed, and
the acceptance process accepts the selection operation input on said selectable objects at the moment when the pointing location initially arrives at the location of a selectable object disposed in the control area, regardless of whether or not the pointing location has been located outside the control area, while the movement of the pointing location on the game screen is maintained by the player's operations.

US Pat. No. 10,335,669

SELF-BALANCING BOARD WITH PRIMARY WHEEL AND DISTAL AUXILIARY WHEEL

Koofy Innovation Limited,...

1. A self-balancing board, comprising:a primary wheel assembly, comprising:
a primary wheel; and
a motor driving the primary wheel;
a platform secured to the primary wheel assembly and having a foot deck;
at least one sensor sensing the orientation of the platform;
a controller receiving data from the at least one sensor and controlling the motor in response to the received data; and
a first auxiliary wheel assembly coupled to the platform distal the primary wheel assembly, the first auxiliary wheel assembly including a first auxiliary wheel that is elevated from contacting a flat surface upon which the primary wheel rests when the foot deck is parallel to the flat surface, and being engaged with the flat surface upon which the primary wheel rests when the foot deck is tilted by a selected angle, so as to cooperate with the primary wheel to support the self-balancing board on the flat surface without triggering braking by the controller on the primary wheel,
wherein the first auxiliary wheel overlaps at least a portion of the primary wheel in a lateral direction and extends laterally across a longitudinal centerline of the primary wheel.

US Pat. No. 10,335,619

FIREFIGHTER MULTIFUNCTION LADDER AND ESCAPE BELT

Fire Innovations LLC, Pe...

1. A multifunction escape and ladder belt, comprising:a front buckle having a first buckle member and a second buckle member, coupling apparatus to connect said first member to said second member, each of said first and second members having a slot through which a fabric side strap may be passed;
left and right adjustment buckles, each configured with rigid bars defining front, middle, and rear adjustment slots through which strap fabric portions may be passed;
left and right side straps, said left side strap connected at a first end to said first buckle member and having a second end threaded through said middle adjustment slot of said left adjustment buckle, then through said front adjustment slot of said left adjustment buckle, and said right side strap connected at a first end to said second buckle member and having a second end threaded through said middle adjustment slot of said right adjustment buckle, then through said front adjustment slot of said right adjustment buckle; and
a rear strap having an outward facing continuous back portion, a first end threaded through said rear slot of said left adjustment buckle and extending to a medial portion of said rear strap, a second end threaded through said rear slot of said right adjustment buckle and extending to said medial portion of said rear strap so as to put said first end and said second end in an overlapping configuration, and first and second energy-release double-loop portions, one of each formed in said rear strap proximate each of said left and right adjustment buckles forming a double-looped overlapping portion secured by stitching;
wherein said stitching forms a stitched strap connection having a predetermined minimum breaking strength.

US Pat. No. 10,335,596

METHOD AND APPARATUS FOR NEUROMODULATION TREATMENTS OF PAIN AND OTHER CONDITIONS

Nalu Medical, Inc., Carl...

1. An apparatus for delivering stimulation energy to tissue, comprising:an implantable device comprising an implantable energy storage element and at least one implantable antenna, the implantable device configured to deliver stimulation energy to tissue;
an external device comprising an external antenna, the external device configured to transmit power and data to the implantable device via a wireless link;
wherein the apparatus is configured to assess quality of the wireless link by assessing rate of charging of the implantable energy storage element,
wherein the apparatus is configured to perform the assessment of the quality of the wireless link periodically,
wherein the apparatus is further configured to increase power level of transmissions during the performance of the assessment, and
wherein the apparatus is further configured to reduce the power level of the external device transmissions until a discharge rate of the implantable energy storage element is faster than the charge rate of the energy storage element.

US Pat. No. 10,335,592

SYSTEMS, DEVICES, AND METHODS FOR IMPROVING HEMODYNAMIC PERFORMANCE THROUGH ASYMPTOMATIC DIAPHRAGM STIMULATION

VisCardia, Inc., Beavert...

1. A method of improving hemodynamic performance of a heart, the method comprising:sensing a plurality of cardiac events directly from a diaphragm;
for each of the sensed cardiac events, determining whether the sensed cardiac event represents a valid cardiac event or a non-valid cardiac event;
establishing a diaphragmatic stimulation delay period based on a plurality of sensed cardiac events that are determined to be valid; and
delivering asymptomatic electrical stimulation therapy directly to the diaphragm based on the established diaphragmatic stimulation delay period.

US Pat. No. 10,335,571

BREATHABLE GAS INLET CONTROL DEVICE FOR RESPIRATORY TREATMENT APPARATUS

ResMed Paris SAS, (FR)

1. A respiratory treatment apparatus configured to provide a flow of breathable gas to a patient in successive respiratory cycles, each cycle including an inspiration phase and an expiration phase, comprising:a gas inlet having a variable aperture that is adjustable between a range of positions from a closed position and to fully open;
a gas outlet; and
a flow generator adapted to provide a supply of pressurized breathable gas from the gas inlet and to the gas outlet, the gas inlet conducting the supply of pressurized breathable gas to the flow generator; and
a controller to control the pressure generated by the flow generator,
wherein the variable aperture is configured to, during the inspiration phase of each respiratory cycle, vary proportionally in opening size as a function of an induced level of flow of breathable gas provided adjacent to the gas outlet, said induced level of flow generated by the patient.

US Pat. No. 10,335,570

METHOD OF SEPARATING AND DISTRIBUTING OXYGEN

3B MEDICAL INC., Winter ...

1. A delivery system for oxygen separated from ambient air comprising:a separator comprising:
at least one separation column, the at least one separation column containing an inlet at a first end and an outlet at a second end;
a last in/first out (LIFO) buffer column having a single inlet at a first end and having an adsorbent with a high capacity for nitrogen adsorption; wherein the LIFO buffer column is configured to receive through the single inlet a first stream of high purity oxygen from the outlet of the at least one separation column, reorder the single stream, and feed a reordered stream of high purity oxygen through the single inlet and to the at least one separation column;
a vacuum pump;
a valve system that connects the vacuum pump with the at least one separation column;
wherein the vacuum pump is connected to the valve system to remove gas from the at least one separation column by enabling a flow path from the at least one separation column to a pump inlet of the vacuum pump, and to transfer a gas into the at least one separation column by enabling a different flow path from a pump outlet to the at least one separation column;
a nose cannula;
wherein the oxygen separator separates oxygen from air in discrete pulses and supplies oxygen through a check valve to the nose cannula directly from the at least one separation column in response to inhalation by a person through the nose cannula.

US Pat. No. 10,335,567

NITRIC OXIDE UPPER AIRWAY DELIVERY SYSTEM AND METHOD

12th Man Technologies, In...

1. A nasal delivery system for delivering nitric oxide-containing gas to an upper respiratory tract of a subject, comprising:a source of nitric oxide-containing gas;
a nasal interface adapted to provide fluid communication between the source of nitric oxide-containing gas and the nostrils of the subject;
a flow-control valve for controlling the flow of the nitric oxide-containing gas from the source to the subject;
a flow sensor positioned near the oral cavity of the subject; and
a control unit in communication with the flow-control valve and the flow sensor;
wherein the control unit is configured to allow delivery of nitric oxide-containing gas to the upper respiratory tract while the soft palate of the subject is open during exhalation of air.

US Pat. No. 10,335,566

SYSTEMS AND METHODS FOR PROVIDING VENTILATION

ADVANCED COOLING THERAPY,...

1. A system for providing ventilation assistance or control, the system comprising:(a) at least one processor;
(b) at least one operator interface configured to provide input to the processor;
(c) at least one input device; and
(d) at least one memory device that stores a plurality of instructions, which when executed by the at least one processor, cause the at least one processor to:
(i) receive, via the at least one operator interface, a first setting for a ventilator parameter and a target pressure for an esophageal pressure of a patient;
(ii) deliver, via at least one conduit, a first volume of gas to the patient in accordance with the first setting;
(iii) receive, via the at least one input device, a measured value for the esophageal pressure;
(iv) determine whether the measured value satisfies the target pressure;
(v) deliver, via the at least one conduit, a second volume of gas to the patient in accordance with a randomized setting in response to determining that the measured value satisfies the target pressure, the randomized setting determined based on a random value that is applied to the first setting of the ventilator parameter;
(vi) deliver, via the at least one conduit, the second volume of gas to the patient in accordance with a corrected setting in response to determining that the measured value does not satisfy the target pressure, the corrected setting determined based on a correction factor that is applied to the first setting of the ventilator parameter; and
(v) adjust the correction factor based upon a magnitude of difference between the measured value and the target pressure of the esophageal pressure of the patient.

US Pat. No. 10,335,554

NEEDLE COVER

Sta-Med, LLC, Irvine, CA...

1. A single-use protective cover, comprising:a housing generally surrounding a needle and configured to connect to a syringe, the needle comprising a central longitudinal axis;
a sleeve configured to move in a first stage with respect to the housing between an extended position and a retracted position substantially without impediment, the sleeve comprising a needle aperture and a needle channel extending axially along the sleeve and configured to receive the needle such that a distal tip of the needle is covered by the sleeve in the extended position and is exposed in the retracted position;
a biasing member configured to bias the sleeve toward the extended position; and
a locking member comprising a central longitudinal axis that is radially offset from the central longitudinal axis of the needle when the sleeve is in the retracted and extended positions;
wherein a distal end of the sleeve is substantially flush with a distal end of the housing when the sleeve is in the retracted position; and
wherein the locking member engages, with an engagement, the sleeve in a second stage as the sleeve moves from the retracted position to the extended position, wherein the engagement between the locking member and the sleeve occurs distal to a proximal-most end of the sleeve and comprises resiliently deflecting the locking member with the sleeve, and wherein the engagement obstructs the sleeve from moving to the retracted position to thereby inhibit reuse of the protective cover.

US Pat. No. 10,335,546

APPARATUS FOR OPTIMIZING A PATIENT'S INSULIN DOSAGE REGIMEN

Hygieia, Inc., Ann Arbor...

1. An apparatus for improving a patient's insulin dosage regimen, comprising:at least one computer-readable memory for storing: programming instructions, data inputs corresponding at least to one or more components in the patient's insulin dosage regimen, and a patient's blood-glucose-level measurements determined at a plurality of times within a predefined period of time;
a timer for monitoring the predefined period of time, the timer being incremented based on at least one of: passage of a separate predetermined increment of time or receipt of at least one of the patient's of blood-glucose-level measurements;
a display operative to display information corresponding to at least the patient's insulin dosage regimen; and
a processor configured to communicate with the at least one computer-readable memory and to execute the programming instructions stored in the at least one computer-readable memory to cause the apparatus to perform a method comprising:
(i) determining a number that represents excessive hypoglycemic events within the predefined period of time;
(ii) determining, after obtaining at least one blood-glucose-level measurement but before obtaining a subsequent blood-glucose-level measurement, whether the obtained blood-glucose-level measurement reflects a hypoglycemic event or a severe hypoglycemic event;
(iii) reducing at least one of the one or more components in the patient's insulin dosage regimen in response to a determination that the obtained blood-glucose-level measurement represents a severe hypoglycemic event;
(iv) reducing at least one of the one or more components in the patient's insulin dosage regimen in response to a determination that the obtained blood-glucose-level measurements results in an excessive number of hypoglycemic events during the predefined period of time; wherein the timer is reinitiated after the determination that there have been an excessive number of hypoglycemic events over the predefined period of time; and
(v) determining, at the end of the predefined period of time, from a plurality of the data corresponding to the patient's blood-glucose-level measurements whether and by how much to vary at least one of the one or more components in the patient's insulin dosage regimen in order to maintain the patient's blood-glucose-level measurements within a predefined range; and
(vi) communicating the revised at least one of the one or more components in the patients insulin dosage regimen to the display to enable the patient's insulin dosage regimen to be updated on the display;
wherein the timer is reinitiated after the determination of whether and by how much to vary at least one of the one or more components in the patient's insulin dosage regimen.

US Pat. No. 10,335,542

FLUID-CONNECTION MECHANISM AND METHODS FOR PATCH-PUMPS

SteadyMed Ltd., Rehovot ...

1. A method of delivering a drug, the method comprising:removing a pin from a patch-pump assembly to automatically cause a penetrator to penetrate a seal of a prefilled drug-reservoir, the patch-pump assembly comprising the penetrator, the prefilled drug-reservoir, a fluid-passageway, a cannula-containing assembly, and a spring-based mechanism;
flowing the drug from the prefilled drug-reservoir to the fluid-passageway;
establishing fluid communication between the fluid-passageway and the cannula-containing assembly using the spring-based mechanism;
flowing the drug from the fluid-passageway to the cannula-containing assembly; and
delivering the drug subcutaneously to a subject using the cannula-containing assembly.

US Pat. No. 10,335,541

PUMP CASSETTES WITH FLOW STOP AND INFUSION PUMP SYSTEMS

CareFusion 2200, Inc., S...

1. A pump cassette comprising: a rigid body comprising two opposing edge sections, an inlet port, an outlet port, and a controllable fluid pathway extending from the inlet port to the outlet port; a slider coupled to the two opposing edge sections and longitudinally articulable along the two opposing edge sections with respect to the rigid body; and a flow stop valve operably coupled to the controllable fluid pathway, wherein the flow stop valve is disposed on the rigid body such that longitudinal articulation of the slider along the two opposing edge sections causes a portion of the slider to actuate the flow stop valve, wherein the flow stop valve is configured to occlude fluid flow through the controllable fluid pathway when the slider is in a first position, and to allow fluid flow through the controllable fluid pathway when the slider is in a second position, wherein the flow stop valve comprises a striker portion coupled to a membrane portion, wherein the portion of the slider is configured to depress the striker portion to urge the membrane portion to occlude fluid flow through the controllable fluid pathway, wherein the striker portion comprises a piece attached to the membrane portion, wherein the portion of the slider is configured to contact the piece to depress the piece when the slider is in the first position, and wherein the piece is configured to align under a recess of the slider such that the slider does not contact the piece when the slider is in the second position.

US Pat. No. 10,335,540

PHARMACEUTICAL BLEND INFUSION THEREOF AND PARKINSON'S DISEASE MONITORING SYSTEM

MICREL MEDICAL DEVICES S....

1. A system for administering a drug to a Parkinson's disease patient comprising (a) a drug, (b) a storing bag for the drug, (c) a pump for administering the drug, and (d) a pump controller for controlling the pump activity,the pump controller having access to a correlation of a first parameter tx and a second parameter At, to a current first parameter tx, and to a mobility calendar indicating start and finish times for particular values of the first parameter tx,
wherein the first parameter tx is correlated with an activity level of the patient and the second parameter At is correlated with a dosage of the drug and the pump controller controls a flow rate of the drug based on changes of the first parameter tx scheduled in the mobility calendar of the first parameter tx and the correlation of the first parameter tx and the second parameter At; and
wherein the controller further has access to a parameter “b”, wherein the controller controls the pump activity in case of a change of the first parameter by a multiplication of parameter b with the difference between an adjusted second parameter At+z that is correlated with an adjusted first parameter t+z after the change and the second parameter At that is correlated with the first parameter tx before the change to amend the dosage z minutes prior to the change by adding the result of the multiplication b*(At+z?At) to the dosage according to the second parameter At, wherein z is the time delay of the drug action being constant for each different drug and infusion path.

US Pat. No. 10,335,528

TRANSCATHETER METHOD AND SYSTEM FOR THE DELIVERY OF INTRACORPOREAL DEVICES

NUHEART AS, Bergen (NO)

1. A method for the transcatheter delivery of an intracorporeal device comprising:a step of establishing a device delivery pathway in a patient, wherein said device delivery pathway extends at least from an entry point into the patient to an exit point from the patient, and
a step of coupling the intracorporeal device to a delivery system, said delivery system being arranged and configured to extend, in use, at least to the entry point and to the exit point of the device delivery pathway,
wherein the delivery system comprises at least two delivery devices, each delivery device being coupled to an end of the intracorporeal device.

US Pat. No. 10,335,510

METHOD AND DEVICE FOR FEMALE URINARY INCONTINENCE

ParaPatch, Inc., Campbel...

1. A patch for treating female urinary incontinence, the patch sized and configured to fit directly on and cover a clitoris without covering a urethra, the patch configured when applied to stimulate the clitoris to inhibit discharge from a bladder.

US Pat. No. 10,335,417

THIAZIDEAMIDE DERIVATIVE AND USE THEREOF

Institute of Pharmacology...

1. A compound, or a pharmaceutically acceptable salt or solvate thereof, wherein the compound is selected from:

US Pat. No. 10,335,409

INHIBITORS OF HEPATITIS C VIRUS

Gilead Pharmasset LLC, F...

1. A compound of formula:

US Pat. No. 10,335,406

OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE

Elysium Therapeutics, Inc...

1. A composition comprising a macromolecule of Formula (I):
and a therapeutically-effective amount of a macromolecule of Formula (II):

or pharmaceutically acceptable salts thereof, wherein:
PD is a gastrointestinal enzyme-labile opioid agonist prodrug and the gastrointestinal enzyme-labile opioid agonist prodrug is:

wherein:
Y is H or OH;
AA is a natural or unnatural amino acid side chain that is recognized by the gastrointestinal enzyme; and
R is independently hydrogen, methyl, ethyl, substituted alkyl, acyl, a natural or unnatural amino acid, or a polypeptide comprising up to 10 natural and/or unnatural amino acids;
I is a gastrointestinal enzyme inhibitor and the gastrointestinal enzyme inhibitor is:

X2 is independently at each occurrence absent or
that joins I to a polymer P2 wherein: k and m are independently at each occurrence an integer from 0 to 10;X1 is independently at each occurrence absent or an ether, an ester, a thioester, an amide, an amine, a carbamate, a carbonate, a thioether, or a urea, wherein the nitrogen atom of the amide, amine, or carbamate, is substituted or unsubstituted and the nitrogen atoms of the urea are each independently substituted or unsubstituted, that joins PD to a polymer P1;
each P1 and P2 is independently a polyalkylene glycol; and
n is independently an integer from 1 to 2.

US Pat. No. 10,335,403

NIACIN FORMULATION

ZEENAR ENTERPRISE PTY LTD...

1. A method for prolonging the release of niacin in a subject, comprising:administering to the oral mucosa of a subject in need thereof a composition comprising an amphiphilic compound capable of self-assembling into a liquid crystalline phase upon contact with a hydrophilic solvent and a therapeutically effective amount of a niacin compound, and
prolonging release of the niacin compound in the subject for up to 12 hours.

US Pat. No. 10,335,394

PROCESSES FOR PREPARING DOLUTEGRAVIR AND CABOTEGRAVIR AND ANALOGUES THEREOF

Lek Pharmaceuticals d.d.,...

1. A process for preparing a compound of formula (I) or a salt thereof
wherein
A represents CH2 or CH2—CH2,
R represents H, C1-C4 alkyl or unsubstituted or substituted phenyl,
X represents O, S, or N—R5, wherein R5 is H or C1-C4 alkyl,
Z represents hydroxy, C1-C4 alkoxy, phenoxy, benzoxy, —NH—Ar or—NH—CH2—Ar,
wherein Ar represents unsubstituted or substituted phenyl, and
* represents a chirality center, which is of (R) or (S) configuration,
the process comprising the steps of
(a) providing a compound of formula (II) or a salt thereof,

wherein A, R, X, Z, and * have the same meaning as above and
Y represents Cl or O—Ra,
wherein Ra represents C1-C4 alkyl or benzyl,
and
(b) carrying out a chemical transformation to obtain the compound of formula (I) and/or a salt thereof,
wherein the transformation is carried out in the presence of a hydroxide and methanol and/or ethanol.

US Pat. No. 10,335,379

ORAL DOSAGE FORMS OF KETAMINE

Develco Pharma Schweiz AG...

1. An oral dosage form comprising ketamine or a pharmaceutically acceptable salt or solvate thereof,wherein the dosage form provides an in vitro release of ketamine, when measured according to the USP Basket Method I in 0.1M HCl at 37° C. at 100 rpm, of 0 to 40% after 2 hours, of 10 to 70% after 4 hours, of 30 to 85% after 6 hours and of 45 to 100% after 8 hours,
wherein the dosage form provides an in vitro release of ketamine, when measured according to the USP 1 Basket Method in 0.1M HCl at 100 rpm, after one hour at 37° C., in an aqueous solution containing 20% by volume of ethanol, in a ratio of less than 2:1 relative to the amount of ketamine released, so measured, after one hour at 37° C. in an ethanol-free aqueous solution,
wherein the dosage form is a multi-particulate controlled release tablet,
wherein the tablet comprises pellets each containing
i) a core comprising
1 to 30 wt. % inert beads,
5 to 400 mg and 1 to 40 wt. % ketamine hydrochloride,
0.01 to 10 wt. % binder, and
0 to 10 wt. % glidant, and
ii) a release control layer comprising
1 to 40 wt. % of a release control substance coated upon the core, wherein the release control substance is a water insoluble polymer,
0.01 to 10 wt % pore builder,
0.01 to 10 wt. % plasticizer, and
0 to 15 wt. % glidant, and
wherein the pellets are contained in an external phase comprising
carboxymethyl cellulose, optionally in the form of a salt, as a pharmaceutically acceptable excipient,
20 to 85 wt. % filler,
0 to 3 wt. % lubricant, and
0 to 5 wt. % glidant,
wherein the tablet optionally comprises an external film coating, and
wherein all wt. % are based on the total weight of the tablet, without the film coating.

US Pat. No. 10,335,346

OPTICAL TECHNIQUES FOR THE MEASUREMENT OF CHEST COMPRESSION DEPTH AND OTHER PARAMETERS DURING CPR

PHYSIO-CONTROL CANADA SAL...

1. A device for monitoring chest compressions during the administration of cardiopulmonary resuscitation to a patient, comprising:a three-dimensional image optical sensor attached to a wrist band configured to be worn around a wrist of a rescuer administering cardiopulmonary resuscitation to the patient, the optical sensor configured to sense a distance, for a plurality of pixels of the optical sensor, between the optical sensor and an object in an environment surrounding the optical sensor, the distance sensed throughout motion of a chest compression administered by the rescuer during cardiopulmonary resuscitation and the object in the environment monitored for changes that are related to the depth of the administered chest compressions, the optical sensor positioned to move with the motion of the chest compression;
processing circuitry configured to receive the sensed distance from optical sensor and further configured to:
generate a depth map from the sensed distance between the optical sensor and the object in the environment of the sensor; and
extract depth information of the chest compression based on the depth map.

US Pat. No. 10,335,343

METHOD AND DEVICE FOR TREATING FEMALE PELVIC NERVE DYSFUNCTION

ParaPatch, Inc., Campbel...

1. A device adapted for providing an inhibitory effect on a bladder of a female person, comprising a patch having a substantially planar skin-contacting surface and sized and configured to be secured directly over and covering a clitoris without covering a urethra of said person, the patch formed of a backing sheet of flexible material with an adhesive layer comprising an adhesive on one side of the backing sheet, the adhesive layer removably connected to a release layer, the patch configured when applied to stimulate the clitoris to inhibit bladder discharge.

US Pat. No. 10,335,336

INCUBATOR

Atom Medical Corporation,...

1. An incubator comprising:an incubator base that is provided on a main strut;
a bed base that is provided on the incubator base and on which a mattress is placed; and
a cassette tray accommodation space which is formed between the incubator base and the bed base, wherein the cassette tray accommodation space comprises at least three tray loading/unloading ports selected from: a front tray loading/unloading port, a rear tray loading/unloading port, a left tray loading/unloading port, and a right tray loading/unloading port.

US Pat. No. 10,335,335

AIR MATTRESS FOR GATCH BED

Paramount Bed Co., Ltd., ...

1. An air mattress placed on a plurality of bottoms including a back bottom, comprising:a plurality of air cells extending to a bed width direction and being arranged in parallel in a bed longitudinal direction;
an air supplying unit for performing supply and discharge of air for each of the air cells; and,
a control unit that inflates and deflates the air cells by increasing and decreasing a pressure of air to be supplied to each of the air cells, wherein
the control unit is configured to:
detect a back tilt angle of the back bottom;
inflate an air cell, of the plurality of air cells, that is in a deflated state when the back tilt angle has reached a first angle; and
perform, after the air cell has been inflated, an inflating and deflating operation of a proper subset of the air cells until a rising operation of the back bottom ends.

US Pat. No. 10,335,332

TOP BAR ACCESSORY FOR WALKER

GANM, LLC, Paris, TN (US...

1. An accessory package for a walker, the accessory package comprising:a cross bar having opposite first and second ends; and
first and second pivot connections configured to connect to the respective first and second ends of the cross bar to the respective laterally opposite sides of a frame of the walker, each of the pivot connections comprising;
an eyelet portion adapted and configured to receive one of the first and second ends of the cross bar, the eyelet portion having a stem with a stem axis extending along a length of the stem; and
an upright piece adapted and configured to be removable attachable to the respective lateral opposite sides of the frame with mechanical fasteners, the upright piece having an outer shape formed to conform to a framework of the walker such that when the upright piece is removably connected to the framework of the walker with the mechanical fasteners, the upright piece is constrained from relative movement with the framework of the walker, the upright piece being adapted and configured to receive the stem and permit adjustment of the length of the stem received within the upright piece along the stem axis, the upright piece being adapted and configured to allow relative rotation of the stem within the upright piece about the stem axis thereby allowing pivoting of the upright piece about the stem axis;
further comprising a locking cap adapted and configured to be fitted to the respective first and second ends of the cross bar to secure the cross bar within the eyelet portion.

US Pat. No. 10,335,325

ERGONOMIC DISPOSABLE ABSORBENT GARMENT

Advanced Absorbent Techno...

1. A disposable absorbent undergarment configured to be worn by a person, said undergarment having a central longitudinal axis and comprising:an absorbent core assembly centered on said central longitudinal axis and having a pair of sides extending parallel to said central longitudinal axis, said absorbent core assembly being of a predetermined width between said sides, and being configured for absorbing fluid from the person; and
a chassis comprising a sheet of a cloth-like, non-woven, breathable material, said sheet having an inner surface, a front section, a back section, and an crotch section located between said front section and said back section, said front section including a top front edge, a pair of front side edges defining therebetween the width of said front section, and a plurality of linear elastic threads extending parallel to said top front edge and to each other completely across said width of said front section from one of said pair of front side edges to the other of said pair of front side edges, said back section including a top back edge, a pair of back side edges defining therebetween the width of said back section, and a plurality of linear elastic threads extending parallel to said top back edge and to each other completely across said width of said back section from one of said pair of back side edges to the other of said pair of back side edges, said crotch section comprising a pair of central side edges defining therebetween the width of said crotch section, the maximum width of said crotch section being less than said width of said front and back sections, said crotch section having and a plurality of linear elastic threads extending parallel to said front top edge, to said back top edge, and to each other completely across said width of said crotch section from one of said pair of central side edges to the other of said pair of central side edges, respective ones of said front side edges being secured to respective ones of said back side edges, each of said pair of central side sections comprising an ergonomically shaped recess forming a respective leg opening for the person, said recesses being spaced apart from each other by a distance which is greater than said predetermined width of said absorbent core assembly, said absorbent core assembly being secured on said inner surface of said chassis at said crotch section and centered on said central longitudinal axis between said respective leg openings with plural ones of said plurality of linear elastic threads of said crotch section at said absorbent core assembly being cut into a plurality of separated segments extending across the entirety of said absorbent core assembly from a point adjacent one of said pair of sides to a point adjacent the other of said pair of sides whereupon some of said plurality of separated segments extend through said central longitudinal axis and others of said plurality of separated segments are located immediately adjacent said central longitudinal axis, said plurality of separated segments being configured so as not to tend to collapse or buckle said absorbent core assembly when said garment is worn by the person.

US Pat. No. 10,335,307

PENILE CONSTRICTION DEVICE

OVO JOINT VENTURE LLC, H...

1. A penile constriction device comprising:a ring-shaped body and an elongated head element having a length that is greater than its maximum width, wherein the head element extends lengthwise in a radial direction relative to the ring-shaped body;
wherein the ring-shaped body has an interior diameter sized to closely encircle a penis, and the head element is removably attached to the ring-shaped body; and
wherein the head element is disposed so that the head element can contact a clitoris during sexual intercourse when the ring-shaped body is positioned on the penis;
wherein the ring-shaped body has an outer peripheral portion at which the head element is provided;
wherein the head element extends in an essentially radial direction relative to the ring-shaped body;
wherein the ring-shaped body is provided with a coupling means for removably mounting the head element to the ring-shaped body; and
wherein the coupling means comprises a protruding portion extending away from the ring-shaped body and wherein the head element includes an opening adapted to accommodate the protruding portion.

US Pat. No. 10,335,302

SYSTEMS AND METHODS FOR USING TRANSCUTANEOUS ELECTRICAL STIMULATION TO ENABLE DIETARY INTERVENTIONS

Elira, Inc., St. Louis, ...

1. A system to generate real-time interventions in response to a patient's degree of appetite, comprising:an electrical dermal patch comprising:
a housing;
a controller positioned within the housing;
at least one electrode positioned in physical communication with the housing and adapted to be in electrical contact with the patient's skin; and,
a pulse generator positioned within the housing and in electrical communication with the controller and said at least one electrode, wherein the pulse generator is configured to generate a plurality of stimulation sessions comprising a plurality of electrical pulses defined by stimulation parameters and wherein said stimulation parameters comprise a first pulse width in a range of 10 ?sec to 10 msec, a first pulse amplitude in a range of 100 ?A to 100 mA, and a first pulse frequency in a range of 1 Hz and 100 Hz;
a first plurality of programmatic instructions stored in a non-transient memory in a client device separate from the electrical dermal patch, wherein, when executed, said first plurality of programmatic instructions is adapted to cause the client device to generate a prompt to the patient to input data indicative of the patient's degree of appetite via a microphone or a display of said client device;
a second plurality of programmatic instructions stored in a non-transient memory in the client device or another device separate from the electrical dermal patch, wherein, when executed, said second plurality of programmatic instructions determines an appetite pattern of the patient based upon said inputted data; and
a third plurality of programmatic instructions stored in a non-transient memory in the client device or another device separate from the electrical dermal patch, wherein, when executed, said third plurality of programmatic instructions determines an intervention and generates said intervention based on the appetite pattern.

US Pat. No. 10,335,300

SYSTEM FOR DEPLOYING A CAPACITIVE SHAPE MEMORY CATHETERIZATION DEVICE AND METHODS FOR USE THEREWITH

Memory Effect Medical, LL...

1. A system for deploying a shape memory catheterization device within a patient, the system comprising: a shape memory polymer that includes a plurality of conductive plates, wherein the shape memory polymer has a transition temperature that is higher than a normal body temperature of the patient; a catheter having a delivery rod for endovascular insertion of the shape memory polymer; a heat source for heating the shape memory polymer above the transition temperature, wherein the heat source utilizes a microwave source that is separate from the shape memory polymer, wherein heating the shape memory polymer above the transition temperature causes the shape memory polymer to undergo a shape transformation from a catheterization shape to a transformed shape, and further causes a change in a capacitance of the shape memory polymer as a result of the shape transformation; a transformation data generator, coupled to the catheter, that includes a power source for driving a detection circuit that monitors the change in the capacitance of the shape memory polymer based on monitoring at least one of: a charging time or a discharging time of the plurality of conductive plates of the shape memory polymer, and generates transformation data based on the change in the capacitance of the shape memory polymer resulting from the shape transformation of the shape memory polymer; a heating control generator that utilizes a processing device and memory to generate a control signal for controlling the microwave source based on the transformation data, wherein the heating control generator generates the control signal to discontinue the heating of the shape memory polymer by the microwave source when the transformation data indicates the shape transformation of the shape memory polymer from the catheterization shape to the transformed shape; and wherein the delivery rod includes a plurality of electrodes that are electrically coupled to a portion of the shape memory polymer to detect the change in capacitance of the shape memory polymer, wherein the delivery rod is removed from the patient in response to the transformation data indicating the shape transformation of the shape memory polymer from the catheterization shape to the transformed shape, and wherein the plurality of electrodes are decoupled from the shape memory polymer to enable removal of the delivery rod from the body of the patient while allowing the shape memory polymer to remain in the body of the patient.

US Pat. No. 10,335,291

HYDRAULIC SYSTEM FOR A KNEE-ANKLE ASSEMBLY CONTROLLED BY A MICROPROCESSOR

PROTEOR, Saint-Apollinai...

1. A femoral knee-ankle prosthesis comprising:a femoral segment suitable for a femoral connection to a user and a tibial segment connected to the femoral segment based on an articulation which reproduces the movements of the knee, the tibial segment being articulated on one foot based on an articulation reproducing the movements of the ankle, a first hydraulic cylinder of which the ends are joined respectively with the femoral and tibial segments, and a second hydraulic cylinder of which the ends are joined respectively with the tibial segment and the foot, an upper chamber of the first hydraulic cylinder is connected to a lower chamber of the second hydraulic cylinder through a conduit connected laterally to the upper chamber of the first hydraulic cylinder, and an electronic control unit that controls both of the first hydraulic cylinder and the second hydraulic cylinder depending on the phase of the walking cycle and a situation faced by the user including a stance phase and a swing phase in such a manner that a first flexion of the knee allows a first dorsiflexion of the ankle in proportion to the movement of the knee during the stance phase and such that a second flexion of the knee results in a second dorsiflexion of the ankle in proportion to the movement of the knee during the swing phase.

US Pat. No. 10,335,288

SURGICAL IMPLANT SECURED BY PEGS AND ASSOCIATED METHODS

SpineSmith Partners, L.P....

1. An artificial disc comprising:an implantable device configured to be secured to two adjacent vertebrae, wherein the implantable device comprises:
an artificial disc that is insertable between a first vertebrae and a second vertebrae, and wherein said artificial disc comprises:
a first end plate comprising a concave inner surface;
a second end plate comprising a concave inner surface, the concave inner surface comprising a concave middle portion and a pair of concave outer portions disposed on opposite sides of the concave middle portion, wherein the pair of concave outer portions have a first curve that is different than a second curve of the concave middle portion; and
a bearing having an upper cylindrically-shaped convex surface and a lower convex surface, wherein the lower convex surface comprises a middle portion; and
wherein a first outer portion of the pair of concave outer portions is configured to be in contact with the bearing when the bearing translates within the concave inner surface of the second end plate in a first direction and a second outer portion of the pair of concave outer portions is configured to be in contact with the bearing when the bearing translates within the concave inner surface of the second end plate in a second direction that is opposite the first direction;
wherein the bearing is adapted to move relative to the first end plate and the second end plate and movement of the bearing relative to first end plate is independent of movement of the bearing relative to the second end plate; and
wherein an axis of the upper cylindrically-shaped convex surface and an axis of the lower convex surface are orthogonal to one another.

US Pat. No. 10,335,282

MAGNETIC JOINT REPLACEMENT

Richard A. Rogachefsky, ...

1. A hip joint prosthesis, comprising:a femoral head comprising a plurality of magnets positioned on an anterior surface of the femoral head, the plurality of magnets comprising a first femoral magnet and a second femoral magnet, the first femoral magnet configured to provide a stronger magnetic field than the second femoral magnet;
an acetabular cup corresponding to the femoral head, the acetabular cup comprising a second plurality of magnets positioned on a posterior surface of the acetabular cup, the second plurality of magnets comprising a first acetabular cup magnet and a second acetabular cup magnet, the first acetabular cup magnet configured to provide a stronger magnetic field than the second acetabular cup magnet;
wherein the femoral head is configured to rotate within the acetabular cup through a range of motion corresponding to about 0-120 degrees of hip flexion, the first femoral magnet positioned on a medial side of the anterior surface of the femoral head and the first acetabular cup magnet positioned on a lateral side of the posterior surface of the acetabular cup such that the first femoral magnet and the first acetabular cup magnet align to form the strongest magnetic force between the first femoral magnet and the first acetabular cup magnet when the femoral head is in a position corresponding to about 90-120 degrees of hip flexion.

US Pat. No. 10,335,267

INTRAOCULAR LENS HAVING PARTLY OVERLAPPING ADDITIONAL OPTICAL ACTIVE SECTORS ON OPPOSITE SIDES

OCULENTIS HOLDING B.V., ...

1. An intraocular lens (1) comprising an optic (3), the optic having first and second sides (3.1, 3.2) and comprising:a first main lens surface (4.1) at the first side (3.1) and a second main lens surface (4.2) at the second side (3.2), the first main lens surface providing a first main lens surface optical power and the second main lens surface providing a second main lens surface optical power,
the first and second main lens surfaces providing a main lens (4) having a main lens optical power to provide distance vision, and a main optical axis (R) defining a radial direction perpendicular to the main optical axis, a tangential direction around the main optical axis and an axial direction along the main optical axis;
a first additional optical active part (6) at the first side (3.1),
the first additional optical active part providing a positive relative optical power with respect to the first main lens surface optical power,
the first additional optical active part (6) being positioned at a distance from the optical axis (R) and in tangential directions being delimited by boundaries extending in radial directions, and
the first additional optical active part (6) overlapping with the second main lens surface (4.2) to form a secondary lens having the positive relative optical power of the first additional optical active part (6) with respect to the main lens (4) to provide near or reading vision;
a central part (8) at the first side (3.1),
the central part being arranged such that the main optical axis (R) passes through the central part, and fitting within a circumscribing circle around the optical axis,
the central part (8) being adjacent to the first additional optical active part (6), and
the central part having a relative optical power between ?2 and 2 diopter with respect to the first main lens surface optical power; and
a second additional optical active part (15) at the second side (3.2),
the second additional optical active part being arranged such that the main optical axis (R) passes through the second additional optical active part, and fitting within a circumscribing circle around the main optical axis (R), and
the second additional optical active part providing a relative optical power and/or an optical aberration with respect to the second main lens surface,
wherein the distance between the main optical axis (R) and the first additional optical active part (6) is smaller than the radius of the circle circumscribing the second additional optical active part (15), the diameter of the circle circumscribing the central part (8) being smaller than the diameter of the circle circumscribing the second additional optical active part (15), such that the second optical active part at least partly overlaps with the first additional optical active part (6) and partly overlaps with the first main lens surface (4.1).

US Pat. No. 10,335,264

VASCULAR GRAFT

Byung Choo Moon, Toronto...

1. An artificial blood vessel, comprising:a cylindrical inner tube having a hollow part formed therein;
an outer tube provided at an outer circumferential surface of the inner tube and surrounding the inner tube so as to form a double tube structure with the inner tube; and
a connecting line formed in circumferential directions of the inner tube and the outer tube to connect the inner tube and the outer tube, wherein the inner tube includes at least a first guide line in an axial direction, and the outer tube includes at least a second guide line in an axial direction and is positioned at a position corresponding to a position of the first guide line.