US Pat. No. 10,190,553

PUMPING UNIT FOR FEEDING FUEL, PREFERABLY DIESEL FUEL, FROM A STORAGE TANK TO AN INTERNAL COMBUSTION ENGINE

Robert Bosch GmbH, Stutt...

1. A pumping unit for feeding fuel from a storage tank (2) to an internal combustion engine (3), the pumping unit comprising:a high-pressure pump (6) for feeding the fuel to the internal combustion engine (3);
a pre-feed pump (7) for feeding the fuel from the storage tank (2) to the high-pressure pump (6);
a transmission shaft (36, 42) for actuating operation of the high-pressure pump (6) and the pre-feed pump (7), the transmission shaft (36, 42) comprising a first portion (36) extending through a pump body (8) of the high-pressure pump (6) and a second portion (42) extending through a pump body (37) of the pre-feed pump (7); and
a hydraulic circuit (46) for connecting together the storage tank (2) and the internal combustion engine (3), the hydraulic circuit (46) comprising a first branch (47) for connecting together the storage tank (2) and the pre-feed pump (7), a second branch (48), which connects together the pre-feed pump (7) and the high-pressure pump (6), and extends through the pump body (8) of the high-pressure pump (6) so as to lubricate the first portion (36) of the transmission shaft (36, 42), a third branch (49) for connecting together the high-pressure pump (6) and the internal combustion engine (3), and a fourth branch (55) for discharging into the storage tank (2) fuel leaks resulting from lubrication of the first portion (36) of the transmission shaft (36, 42); wherein the fourth branch (55) is also connected to an intake (37a) of the pre-feed pump (7) so as to lubricate the second portion (42) of the transmission shaft (36, 42) with the fuel of the fourth branch (55);
wherein the pump body (37) of the pre-feed pump (7) comprises a tubular support bush (41) engaged rotatably by the second portion (42) of the transmission shaft (36, 42); the fourth branch (55) extending through the pump body (8) of the high-pressure pump (6) so as to be connected to the tubular support bush (41).

US Pat. No. 10,190,549

CHECK VALVES AND VENTURI DEVICES HAVING THE SAME

Dayco IP Holdings, LLC, ...

1. A check valve comprising:a housing defining an internal cavity having a first port and a second port both in fluid communication therewith and having a first seat and a second seat, the first seat being proximate the first port;
a seal disk within the internal cavity, wherein the seal disk is translatable between a closed position against the first seat and an open position against the second seat; and
an outlet conduit extending from the second port, wherein the outlet conduit defines an outlet passageway and an outlet end, wherein the outlet passageway has a restrictor profile;
wherein the restrictor profile has a first portion more proximate the second port and a second section more proximate the outlet end, wherein as viewed in a transverse cross-section both the first portion and the second portion are circular;
wherein the first portion narrows according to a parabolic or hyperbolic function along a length of the first portion in the downstream direction.

US Pat. No. 10,190,546

INTAKE MANIFOLD

AISAN KOGYO KABUSHIKI KAI...

1. An intake manifold comprising:a surge tank;
a plurality of branch pipes branching off from the surge tank;
an EGR gas distribution part for distributing EGR gas to each of the branch pipes;
an EGR cooler configured to cool the EGR gas to be introduced into the EGR gas distribution part, the EGR cooler and the EGR gas distribution part being provided adjacent to and integral with each other outside the surge tank and the plurality of branch pipes; and
an EGR valve configured to regulate a flow rate of the EGR gas to be introduced into the EGR gas distribution part through the EGR valve after the EGR gas having flowed in the EGR cooler passes through the EGR cooler,
wherein the EGR cooler includes a gas passage through which the EGR gas flows and a water passage through which cooling water in an engine flows to cool the gas passage, and
the intake manifold is configured to allow the EGR gas to pass through the EGR cooler and then flow in the EGR gas distribution part through the EGR valve, and distribute the EGR gas into the plurality of branch pipes so that the EGR gas merges with intake air that flows through the branch pipes.

US Pat. No. 10,190,543

METHOD OF OPERATING INTERNAL COMBUSTION ENGINE HAVING INCREASED RICH LIMIT FOR DEDICATED EGR CYLINDER

SOUTHWEST RESEARCH INSTIT...

1. A method of operating an engine having at least one dedicated EGR cylinder, with the remaining cylinders being main cylinders, comprising:operating the main cylinders at a first air-fuel ratio;
determining a rich operating limit of the dedicated EGR cylinder operating without internal EGR;
operating the dedicated EGR cylinder at a second air-fuel ratio that is at or below the rich operating limit;
controlling the intake and/or exhaust valves of the main cylinders such that the main cylinders retain exhaust gas, thereby providing internal EGR to only those cylinders, during all or some operating conditions of the engine; and
controlling the intake and/or exhaust valves of the dedicated EGR cylinder independently of the intake and/or exhaust valves of the dedicated EGR cylinder, such that the dedicated EGR cylinder never receives internal EGR at any load of the engine.

US Pat. No. 10,190,475

METHOD FOR MANUFACTURING A DOUBLE PIPE

NAKAGAWA SANGYO CO., LTD....

1. A method for manufacturing a double pipe having a curved inner pipe disposed within a curved outer pipe, the method comprising:drawing a plate, which has a predetermined shape that at least substantially corresponds to a final shape of the curved outer pipe, into a curved, substantially U-shape in cross-section, thereby producing a curved U-shaped intermediate part;
disposing the curved inner pipe, which has a curved shape that is at least substantially similar to the final shape of the curved outer pipe, in an interior space of the curved U-shaped intermediate part;
welding together the curved inner pipe and the curved U-shaped intermediate part at one longitudinal end thereof;
then bending longitudinally-extending edges of the curved U-shaped intermediate part so that the longitudinally-extending edges come into abutment and an at least substantially circular cross-section is formed, thereby forming the curved outer pipe that encloses the inner pipe; and
welding together the abutting longitudinally-extending edges of the curved outer pipe.

US Pat. No. 10,190,413

METHODS AND DEVICES FOR EVALUATING THE CONTENTS OF MATERIALS

Michael P. Smith, Tulsa,...

1. A method for analyzing the mechanical strength of a geologic formation comprising:a. Placing a plurality of separated samples of material obtained from the geologic formation into a container, the container comprising a top, bottom, and two or more sides,
b. Subjecting the container to one or more compression forces, wherein at least one of the one or more compression forces are applied to at least two sides of each container, and the samples interact with at least two sides of the container,
c. Determining the amount of compression of the container, and
d. Assessing the mechanical strength of the geologic formation by evaluating the compression of the container comprising the samples.

US Pat. No. 10,190,381

VARIABLE RATIO ROTARY ENERGY CONTROL DEVICE FOR A BLOWOUT PREVENTER SAFETY DEVICE

HilFlo, LLC, Conroe, TX ...

7. A method of controlling the operation of a safety device of a blowout preventer, the safety device being operated by hydraulic fluid under pressure comprising:providing a source of fluid under pressure;
providing a variable ratio rotary energy controller connected between the source of fluid under pressure and the safety device; and
initiating the flow of fluid under pressure to the safety device of the blowout preventer through the variable ratio rotary energy controller,wherein the variable ratio rotary control device includes a variable displacement hydraulic motor having an input port and an outlet port, an output shaft connected to an input shaft of a variable displacement hydraulic pump, the pump including an inlet port and an outlet port, anddirecting fluid from the variable displacement hydraulic motor outlet port to the fluid inlet port of the variable displacement hydraulic pump.

US Pat. No. 10,190,376

APPARATUS AND METHOD FOR CONTROLLING A DOWNHOLE DEVICE

NXG Technologies Limited,...

26. A method of controlling a downhole device in an oil, gas or water well, the method comprising providing an apparatus comprising a body having a control slot and a pin on separate relatively movable components so that the slot engages the pin and the pin and slot are configured to be movable relative to one another, and moving the pin relative to the slot to switch the downhole device between active and inactive states,wherein the method comprises moving the pin in at least one loop of the slot wherein the at least one loop had a blind ended axial portion and defines different idling configurations of the pin and slot in which the device is inactive, and moving the pin in at least one elongated axial track of the slot,
wherein the at least one elongated axial track of the slot is arranged in the axial direction of the body and has a length in the axial direction longer than the blind ended axial portion,
wherein the at least one elongated axial track defines different configurations of the pin and slot which correspond to active and inactive configurations of the downhole device,
wherein the method comprises moving the pin from one of the at least one elongated axial track to one of the at least one loop via a deviate branch track,
wherein the slot has no separate, dedicate return path for returning the pin from the deviate branch track to the elongated axial track, and
wherein the method includes cycling the pin between the different configurations within the at least one loop without switching the pin from the at least one loop to one of the at least one elongated axial track.

US Pat. No. 10,190,342

DOOR LOCK MECHANISM FOR VEHICLE

HYUNDAI MOTOR INDIA ENGIN...

1. A door lock mechanism for a vehicle, comprising:an outside handle lever;
a lock pin which is movable between an unlocked position and a locked position in a radial direction from a rotation axis of a pawl lever rotatable by a rotating displacement of the outside handle lever, wherein at the unlocked position, the rotating displacement of the outside handle lever is transmitted to the pawl lever, and at the locked position, the rotating displacement of the outside handle lever is not transmitted to the pawl lever;
a lock lever which is selectively rotated to allow the lock pin to be moved in the radial direction;
a safety lever engaged with the lock lever, the safety lever receiving a manipulation force of a safety knob and rotating the lock lever; and
an interlinking unit which allows a rotating displacement of the pawl lever to be partly transmitted to the safety lever,
wherein the interlinking unit comprises: an elongated element, a first end of which is rotatably fixed to the safety lever and a second side of which protrudes towards the pawl lever so that, in a returned state where the pawl lever is not subjected to the manipulation force, but is only applied with an elastic force of a return spring, the elongated element is separated from the pawl lever, and wherein the pawl lever is configured to allow the rotating displacement of the pawl lever to transmit to the safety lever via the elongated element,
wherein a pawl which is rotated in cooperation with the pawl lever is elastically supported by the return spring such that the pawl receives the elastic force of the return spring and thus restricts a rotation of a claw,
wherein the lock lever is rotated along with a rotation of the safety lever by the interlinking unit, to move the lock pin into the unlocked position,
wherein the pawl lever is provided, on an end side thereof, with a bent part which is bent perpendicularly from a rotating surface of the pawl lever,
wherein the elongated element is mounted to protrude towards and thus come into contact with the bent part of the pawl lever,
wherein an inside handle lever is mounted to, upon rotation, transmit a manipulation force of an inside handle to the pawl lever via the bent part of the pawl lever,
wherein the elongated element is provided, on a lower end thereof, with a protrusion which is faced with the bent part such that the protrusion come into direct contact with the bent part of the pawl lever upon rotation of the pawl lever, and the protrusion is integrally formed with the elongated element,
wherein the pawl lever is rotated in cooperation with the pawl;
wherein the pawl restricts or allows a rotation of the claw which has engaged with a striker by rotation thereof; and
wherein the claw engages with and disengages from the striker by rotation thereof.

US Pat. No. 10,190,336

MAGNETICALLY ACTIVATED DOOR-LOCK DEVICE

BITRON S.P.A., Turin (IT...

1. A door-lock device for a household appliance, said door-lock device comprising:a mechanical unit, provided with a movable member capable of assuming a releasing position in which the movable member allows for opening of a door, and a locking position, for retaining said door in a closed position, and
a control unit for connection with control logic of said household appliance, the control unit comprising a locking pin capable of assuming at least one position in which the locking pin is disengaged from said movable member, and an extracted position, in which said locking pin is capable of engaging with said movable member when the movable member is in said locking position, said movable member being capable to pass from said locking position to said releasing position when said locking pin is disengaged from said movable member,
wherein said control unit further comprises:
an electromagnet having a solenoid that is electrically powered to change a polarity of said solenoid, said electromagnet being provided with an air gap,
a switching assembly comprising a magnet, said switching assembly being arranged in said air gap, and being capable of assuming a first and a second position, according to the polarity of a magnetic field in said air gap, generated by said solenoid, said switching assembly comprises a container, laterally provided with a relief,
said switching assembly further comprising a container, laterally provided with a relief, and said locking pin has a guide, substantially “S”-shaped, in which said relief of said container is slidingly inserted such that rotation of said switching assembly between its first and second positions causes a translation of said locking pin between the at least one position in which the locking pin is disengaged from the movable member and the extracted position, and
an activation switch for controlling a power supply load, wherein said locking pin is kinematically constrained to said switching assembly, such that when said switching assembly is in said first position, said locking pin is disengaged from said movable member of said mechanical unit, and when said switching assembly is in said second position, said locking pin is in said extracted position, causing a closure of said activation switch.

US Pat. No. 10,190,309

SLAB CONSTRUCTION SYSTEM AND METHOD FOR CONSTRUCTING MULTI-STORY BUILDINGS USING PRE-MANUFACTURED STRUCTURES

Innovative Building Techn...

1. A method of constructing a multi-story building, the method comprising:installing a load-bearing structural frame around a perimeter of a foundation;
in response to the installation of the load-bearing structural frame, hoisting and positioning a plurality of slabs to different elevations from a base level of the load-bearing structural frame, wherein each slab of the plurality of slabs is configured to span a complete story of the multi-story building, and wherein hoisting and positioning comprises:
forming and pouring the plurality of slabs, at the base level, to attach to the load-bearing structural frame at each building level, wherein a lower slab between successive slabs of the plurality of slabs is configured to be a formwork for an upper slab;
prior to hoisting each of the lower slabs, loading each of the lower slabs with one or more pre-manufactured non-weight bearing walls, and, optionally, one or more exterior window walls, one or more interior components, or one or more exterior components;
hoisting and positioning the upper slab at a top of the multi-story building, wherein the upper slab positioned at the top of the multi-story building corresponds to a roof slab;
hoisting and positioning other slabs of the plurality of slabs at each successive level of the multi-story building, in a downward sequential manner, wherein hoisting and positioning the other slabs in the downward sequential manner corresponds to hoisting and positioning the other slabs successively beneath the roof slab of the multi-story building, until the construction of the multi-story building is complete; and
attaching the one or more pre-manufactured non-weight bearing walls between hoisted slabs, wherein the one or more pre-manufactured non-weight bearing walls include an interior surface and an exterior surface.

US Pat. No. 10,190,260

FLUFF PULP AND HIGH SAP LOADED CORE

INTERNATIONAL PAPER COMPA...

1. A fluff pulp composition, comprising:softwood fibers;
8 to 23% by weight of hardwood fibers; and
one or more superabsorbent polymer (SAP),
wherein the fluff pulp composition has a SAP retention value greater than 75%.

US Pat. No. 10,190,246

TUFTING MACHINE DRIVE SYSTEM

Card-Monroe Corp., Chatt...

1. A tufting machine for forming tufted articles, comprising:backing feed rolls feeding a backing material through the tufting machine;
at least one needle bar having a plurality of needles mounted therealong, each of the needles carrying a yarn for forming tufts of yarns in the backing material as the needles are reciprocated into and out of the backing material;
a first directional drive component including a series of push rods for driving the at least one needle bar in a first direction along its reciprocating motion, and a series of needle bar support brackets coupled to the push rods, the needle bar support brackets including linear motion bearing guides each having a series of linear motion bearings arranged therealong and configured to slidably receive a guide track mounted to the at least one needle bar as the at least one needle bar is moved in a second direction and the at least one needle bar is reciprocated in the first direction; and
a second directional drive component including at least one shift mechanism connected to the at least one needle bar by at least one connecting arm assembly, the at least one connecting arm assembly comprising a guide arm mounted to the at least one needle bar and a linear bearing assembly bracket having linear motion bearings therealong and defining a channel through which the guide arm is received during the reciprocating movement of the at least one needle bar in its first direction while the at least one needle bar is moved in its second direction substantially transverse to the first direction by the at least one shift mechanism.

US Pat. No. 10,190,230

CROSS FLOW MANIFOLD FOR ELECTROPLATING APPARATUS

Novellus Systems, Inc., ...

1. A method for electroplating a substrate, the method comprising:(a) receiving the substrate in a substrate holder, the substrate being substantially planar, wherein a plating face of the substrate is exposed, and wherein the substrate holder is configured to hold the substrate such that the plating face of the substrate is separated from an anode during electroplating;
(b) immersing the substrate in electrolyte, wherein a gap of about 10 mm or less is formed between the plating face of the substrate and an upper surface of an ionically resistive element, wherein the ionically resistive element is at least coextensive with the plating face of the substrate, and wherein the ionically resistive element is adapted to provide ionic transport through the ionically resistive element during electroplating;
(c) flowing electrolyte in contact with the substrate in the substrate holder from a side inlet, into the gap, and out a side outlet, wherein the side inlet and side outlet are positioned proximate azimuthally opposed perimeter locations on the plating face of the substrate, and wherein the side inlet and side outlet are designed or configured to generate cross-flowing electrolyte in the gap during electroplating;
(d) rotating the substrate holder; and
(e) electroplating material onto the plating face of the substrate while flowing the electrolyte as in (c).

US Pat. No. 10,190,229

INTERIOR PLATING AND AUTOMATED SURFACE-DEPOSITION SYSTEM

OCEANIT LABORATORIES, INC...

1. A system, comprising:a plurality of modular segments flexibly attached to one another; and
sources of electrical power and plating and coating solutions;
wherein the plurality of modular segments comprise:
a drive stage configured to push the plurality of modular segments along a surface;
a plating stage configured to apply the plating solution to the surface; and
a surface treatment application stage configured to apply the coating solution to the surface, which will cure to form a final coating on the surface that is resistant to corrosion and buildup.

US Pat. No. 10,190,207

EVAPORATION METHOD

BOE TECHNOLOGY GROUP CO.,...

1. An evaporation method, comprising:evaporating evaporation material and forming evaporation material particles towards one or more transfer substrates by means of an evaporation source, so as to form an intermediate material layer on a surface of the transfer substrate;
heating the one or more transfer substrates to evaporate the intermediate material layer located on the transfer substrate towards a target substrate, a temperature of the heated transfer substrate being less than a temperature of the evaporation source,
wherein an area of the surface of the one or more transfer substrates receiving the evaporation material particles is greater than an area of an outlet of the evaporation source.

US Pat. No. 10,190,155

MOLECULAR TAG ATTACHMENT AND TRANSFER

NuGEN Technologies, Inc.,...

1. A method of determining a modification of a DNA sample, the method comprising:preparing a double-stranded DNA fragment linked with a plurality of oligonucleotide adaptors, the double-stranded DNA fragment comprising a nucleic acid sequence of interest;
denaturing the double-stranded DNA fragment, thereby generating a first strand DNA fragment and a second strand DNA fragment;
annealing a first probe to the first strand DNA fragment, the first probe comprising a probe oligonucleotide sequence complementary to and hybridizing to a first probe target region associated with the nucleic acid sequence of interest;
extending the first probe with a DNA polymerase using the first strand DNA fragment as a template, thereby generating a probe extension sequence;
annealing a primer or a second probe to the second strand DNA fragment, the primer and the second probe comprising a tag sequence;
generating an extension sequence using the primer or the second probe, the extension sequence including the tag sequence or a complement of the tag sequence; and
sequencing the extension sequence and the probe extension sequence, thereby determining the modification of the DNA sample based on existence or absence of the tag sequence or a complement of the tag sequence, wherein the annealing the primer or the second probe to the second strand DNA fragment and generating the extension sequence using the primer or the second probe comprises:
annealing the second probe to the second strand DNA fragment, the second probe comprising a non-extendable probe sequence and a tag sequence, the non-extendable probe sequence complementary to and hybridizing to a second probe target region associated with the nucleic acid sequence of interest;
annealing a primer sequence to a 3? end of the second strand DNA fragment;
extending the primer sequence with the DNA polymerase using the second strand DNA fragment as a template, thereby generating a primer extension sequence; and
ligating the primer extension sequence and the second probe, thereby generating the extension sequence comprising the tag sequence.

US Pat. No. 10,190,087

SINGLE USE CONTROLLED ENVIRONMENT MODULE

GE HEALTHCARE BIO-SCIENCE...

1. A single use, controlled environment manufacturing module comprising:a sealed bag formed of a substantially flexible material, the sealed bag having sterile interior and an exterior and capable of being inflated with air or gas, such that an environment within the sealed bag is sterile and is segregated from an ambient environment outside of the sealed bag;
at least one external connector, the at least one external connector comprising at least one of an aseptic connector and a tubing connector that extend from the exterior of the sealed bag to the interior of the sealed bag;
at least one set of access ports configured to provide hand-access to the interior of the sealed bag; and
a central controller operative to control and monitor the environment within the sealed bag and a manufacturing process conducted within the sealed bag;
wherein a sterile environment is achieved and maintained within the bag without clean-in-place or sterilization-in-place operations.

US Pat. No. 10,190,073

LIPID COMPRISING LONG CHAIN POLYUNSATURATED FATTY ACIDS

COMMONWEALTH SCIENTIFIC A...

1. A process for producing extracted plant lipid, comprising the steps of:i) obtaining a Brassica sp. seed comprising extractable lipid having a total fatty acid content comprising fatty acids in an esterified form, the fatty acids comprising oleic acid, palmitic acid, ?6 fatty acids which comprise linoleic acid (LA), ?3 fatty acids which comprise ?-linolenic acid (ALA), stearidonic acid (SDA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA), and optionally one or more of eicosapentaenoic acid (EPA) and eicosatetraenoic acid (ETA), wherein (a) the level of palmitic acid in the total fatty acid content of the extractable lipid is between about 2% and 16%, (b) the level of myristic acid (C14:0) in the total fatty acid content of the extractable lipid is less than 1%, and (c) the level of DHA in the total fatty acid content of extractable lipid in the plant part is between 20.1% and 30%, and
ii) extracting lipid from the Brassica sp. seed to thereby produce extracted plant lipid.

US Pat. No. 10,190,068

GIANT ELECTRORHEOLOGICAL FLUID SURFACTANT ADDITIVES

THE HONG KONG UNIVERSITY ...

1. A method for preparing giant electrorheological (GER) fluids, comprising the steps of:grinding a nanoparticle composite comprising urea and 0.2-5.0 wt % sodium dodecylbenzenesulfate (SDBS);
agitating the ground composite via ultrasonification for at least 30 minutes at 20-40° C.;
drying the composite for at least 12 hours in a freeze drying machine; and
suspending the composite in a non-conducting oil.

US Pat. No. 10,190,066

METHOD AND SYSTEM FOR BIOMASS HYDROGASIFICATION

G4 Insights Inc., Burnab...

1. A method, comprising:pyrolyzing biomass to produce a pyrolysis gas and char;
hydrogasifying the pyrolysis gas in the presence of a catalyst and hydrogen produced by a hydrogen generator powered by a renewable energy source, to produce a gas mixture;
separating the gas mixture into a substitute natural gas stream and a residual gas stream.

US Pat. No. 10,190,063

PRODUCTION OF OILFIELD HYDROCARBONS

Sasol Technology Propriet...

1. A process to produce olefinic products in the carbon range C16-C30 suitable for use as or conversion to oilfield hydrocarbons, the process comprising:separating an olefins-containing Fischer-Tropsch condensate into a light fraction which is a C5-C7 fraction, an intermediate fraction which is a C8-C15 fraction which includes paraffins and alpha-olefins and a heavy fraction which is a C16-C22 fraction which includes paraffins and alpha-olefins;
oligomerising at least a portion of the light fraction using a zeolitic catalyst to produce a first olefinic product which includes branched internal olefins;
carrying out either one or both of the steps of:
(i) dehydrogenating at least a portion of the intermediate fraction to convert the paraffins to internal olefins thereby to produce an intermediate product which includes internal olefins and alpha-olefins, and synthesising higher olefins, by means of dimerisation or olefin metathesis, from the intermediate product which includes internal olefins and alpha-olefins to produce a second olefinic product; and
(ii) dimerising at least a portion of the intermediate fraction to produce a second olefinic product; and
dehydrogenating at least a portion of the heavy fraction to convert the paraffins to internal olefins thereby to produce a third olefinic product which includes internal olefins,
the first olefinic product and the second olefinic product being such that a combination of the first olefinic product and the second olefinic product provides an olefinic product with at least 50% by mass of hydrocarbons having carbon chain lengths of between 15 and 30 carbon atoms per molecule.

US Pat. No. 10,190,057

FISCHER-TROPSCH SYNTHESIS

SASOL TECHNOLOGY PROPRIET...

1. A method of synthesising Fischer-Tropsch products, the method includingfeeding a synthesis gas to a moving-bed Fischer-Tropsch synthesis reactor containing a Fischer-Tropsch catalyst in a moving catalyst bed, catalytically converting at least a portion of the synthesis gas in the moving catalyst bed to Fischer-Tropsch products and withdrawing the Fischer-Tropsch products from the moving-bed Fischer-Tropsch synthesis reactor,
the method further including, while the moving-bed Fisher-Tropsch synthesis reactor is on-line:
withdrawing a portion of the Fischer-Tropsch catalyst from the moving-bed Fischer-Tropsch synthesis reactor;
discarding from about 15 wt % to about 60 wt % of the withdrawn Fischer-Tropsch catalyst;
adding a reactivated Fischer-Tropsch catalyst to the moving-bed Fischer-Tropsch synthesis reactor; and
adding a fresh Fischer-Tropsch catalyst, in addition to the reactivated catalyst, to the moving-bed Fischer-Tropsch synthesis reactor.

US Pat. No. 10,190,036

MULTIFUNCTIONAL FOAMING COMPOSITION WITH WETTABILITY MODIFYING, CORROSION INHIBITORY AND MINERAL SCALE INHIBITORY/DISPERSANTS PROPERTIES FOR HIGH TEMPERATURE AND ULTRA HIGH SALINITY

INSTITUTO MEXICANO DEL PE...

1. A multifunctional foaming composition, characterized by the combination of supramolecular complexes derived from the interaction of:(a) an alkyl amido propyl hydroxysultaine and/or alkyl amido propyl betaines and/or alkyl hydroxysultaines and/or alkyl betaines;
(b) an anionic surfactant, which is a mixture of
(b1) alkyl hydroxy sulphonates of sodium; and
(b2) alkenyl sulphonates of sodium;
(c) a cationic surfactant which is tetra-alkyl ammonium halides; and
optionally, (d) copolymers derived from itaconic acid/vinyl sulfonate of sodium and/or terpolymers derived from itaconic acid/sodium vinyl sulphonate/aconitic acid.

US Pat. No. 10,190,017

PROTECTIVE FILM-FORMING FILM AND METHOD OF MANUFACTURING SEMICONDUCTOR CHIP WITH PROTECTIVE FILM

Lintec Corporation, Toky...

1. A protective film-forming film for forming a protective film which protects a metal film provided on a back surface of a semiconductor chip,wherein the protective film-forming film is formed of a protective film-forming composition to which a coupling agent having a protected thiol group is added, and
wherein the protective group in the protected thiol group includes at least one of the group consisting of a trialkoxysilyl group, a trialkylsilyl group, a trialkylsiloxy group, a carbamate group, a carbonate group, and an acetyl group, and
wherein the coupling agent has a protected thiol group at a terminal of the molecule,
wherein the coupling agent is composed of a compound represented by the following formula (1), and
wherein the protective film-forming composition includes an acrylic resin having a glass transition temperature of ?3 to 6 ° C., and
(R1O)3—Si—X1—S—Y1  formula (1)wherein R1 represents an alkyl group in which three R1s may be the same as or different from each other; X1 represents an alkylene group; and Y1 represents the protective group in the protected thiol group.

US Pat. No. 10,190,009

INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL

NIPPON KAYAKU KABUSHIKI K...

1. An ink composition comprising a coloring matter represented by the following formula (3) and a coloring matter represented by the following formula (b4):
wherein the coloring matter represented by formula (3) is from 40% to ? by mass of the total amount of the coloring matters in the ink composition.

US Pat. No. 10,189,996

ANTHRACENE-BASED ORGANIC DYE

NATIONAL CHI NAN UNIVERSI...

1. An anthracene-based organic dye represented by Formula (1):
wherein
s, m, and n represent independently 0 or 1;
Q is an anchoring group selected from the group consisting of

 wherein X1, X2, X3, X4, X5, X6, X7, and X8 are independently selected from the group consisting of hydrogen, lithium, sodium and

 wherein Z1, Z2, Z3, and Z4 represent independently a C1-C6 alkyl group;
P is an electron acceptor group selected from the group consisting of

 wherein T1, T2, T3, and T4 are independently selected from the group consisting of hydrogen, fluoro, a C4-C12 alkyl group, and a C4-C2 alkoxy group, and T5 is selected from the group consisting of hydrogen and a C4-C17 alkyl group; and
R is an electron donor group with the proviso that
R is selected from the group consisting of

 when s represents 1, and
R is selected from the group consisting of

 when s represents 0,
wherein
Y1, Y2, Y3, Y4, Y9, Y10, Y11, Y12, Y13, Y14, Y15, Y16, Y17, Y18, Y21, Y22, Y23, and Y24 are independently selected from the group consisting of hydrogen and a C4-C12 alkyl group, and
Y5, Y6, Y7, Y8, Y19, and Y20 are independently selected from the group consisting of hydrogen, fluoro, a C4-C12 alkyl group, and a C4-C12 alkoxy group.

US Pat. No. 10,189,994

USE OF A WAX-MODIFIED, AIR RECTIFIED ASPHALT IN BUILT UP ROOFING ASPHALT COMPOSITIONS

Owens Corning Intellectua...

1. A heat stable asphalt composition that meets ASTM D 312 (2006) built-up roofing asphalt (“BURA”) specifications, the heat stable asphalt composition comprising:an air rectified asphalt; and
a wax additive, wherein the additive has a melt point higher than about 100° C.;
wherein the composition has an equiviscous temperature (EVT) of from about 340° F. to about 390° F. for mopping applications and from about 380° F. to about 430° F. for mechanical applications, and wherein the composition has a minimum solubility in trichloroethylene of 99%.

US Pat. No. 10,189,985

POLYACRYLONITRILE (PAN) POLYMERS WITH LOW POLYDISPERSITY INDEX (PDI) AND CARBON FIBERS MADE THEREFROM

CYTEC INDUSTRIES INC., P...

1. A method for synthesizing a polyacrylonitrile (PAN) polymer with a narrow molecular weight distribution, the method comprising:a) combining acrylonitrile (AN) monomer with a solvent, at least one co-monomer, and a thiocarbonylthio compound to form a solution;
b) heating the solution to a temperature within the range of 40° C. 85° C.; and
c) adding an initiator to the heated solution to affect polymerization reaction, thereby forming a polymer solution comprising polyacrylonitrile (PAN) polymer,
wherein polymerization is affected by controlled/living radical polymerization, in which the thiocarbonylthio compound functions as a Reversible Addition/Fragmentation Chain Transfer (RAFT) agent,
wherein the thiocarbonylthio compound is selected from the following structures:

where Z1 is selected from:
—CH2—(CH2)10—CH3; —(CH2)n—CH3, n=0-20;
—C(CH3)m—COOH, m=1-2; —C(CH3)m—COOCH3, m=1-2;
—C(CH3)m—COOC2H5, m=1-2;
R1 is selected from:

R?1 is selected from: —CN;

x=0-1;
R?1 is selected from: H; —CH3; —(CH2)m—COOH, m=1-2;
R??1 is H or —CH3

where Z2 is selected from:

R is selected from: F, Cl, CN, OCH3;
R2 is selected from:

R?2 is selected from: —CN;

x=0-1;
—C(CH3)m—COOCH3, m=1-2;
—C(CH3)m—COOC2H5, m=1-2;
R?2 is selected from: H; —CH3; —(CH2)m—COOH, m=1-2;
R??2 is H or —CH3

where Z3 is selected from: —CH2—(CH2)10—CH3; —(CH2)y—CH3, y=1-20;
R3 is selected from: —CH2—(CH2)10—CH3; —(CH2)y—CH3, y=1-20,
wherein the PAN polymer has a polydispersity index (PDI) of about 2 or less and a molecular weight within the range of 60 kg/mole to 500 kg/mole.

US Pat. No. 10,189,956

POLYMER SUBSTRATES FORMED FROM CARBOXY FUNCTIONAL ACRYLAMIDE

LIFE TECHNOLOGIES AS, Os...

1. A compound of the formula:
wherein R1 is an alkyl group having between 3 and 10 carbons or is a polyether group having between 1 and 10 ether units, wherein R2 is a linear or branched alkyl group having between 3 and 8 carbons or a silyl group, and wherein R3 is hydrogen or an alkyl group having between 1 and 6 carbons.

US Pat. No. 10,189,938

POLYUREA COMPOSITION

SIKA TECHNOLOGY AG, Baar...

1. A method comprising treating a substrate comprising an elastomeric material having unsaturated units with a curable composition, said treating selected from the group consisting of patching a defect in the substrate, coating the substrate, and adhesively bonding the substrate to another substrate, and said composition comprising at least, a first component and a second component, whereinthe first component K1 comprises
one or more than one di(aminobenzoate) ester A1 of formula (I)

with an average molecular weight of 500 g/mol to 2000 g/mol, where G is a divalent moiety deriving from poly(tetramethylene oxide) diol, and
the second component K2 comprises
one or more than one aromatic polyisocyanate B1 with an average molecular weight of 160 g/mol to 1100 g/mol, wherein the molar ratio between the isocyanate groups of the second component K2 and the isocyanate-reactive groups of the first component K1 is in the range from 1.3 to 1.0.

US Pat. No. 10,189,894

RATIONALLY DESIGNED, SYNTHETIC ANTIBODY LIBRARIES AND USES THEREFOR

Adimab, LLC, Lebanon, NH...

1. An antibody isolated from a library comprising synthetic polynucleotides that encode an antibody heavy chain and an antibody light chain containing at least about 106 unique antibody CDRH3 amino acid sequences, wherein each of the polynucleotides encoding the at least about 106 unique antibody CDRH3 amino acid sequences has an antibody CDRH3 amino acid sequence represented by the following formula:[X]-[N1]-[DH]-[N2]-[H3-JH], wherein
(i) X is selected from the group consisting of G, D, E and nothing;
(ii) N1 is an amino acid sequence selected from the group consisting of G, P, R, A, S, L, T, V, GG, GP, GR, GA, GS, GL, GT, GV, PG, RG, AG, SG, LG, TG, VG, PP, PR, PA, PS, PL, PT, PV, RP, AP, SP, LP, TP, VP, IG, KG, GW, FP, EG, GGG, GPG, GRG, GAG, GSG, GLG, GTG, GVG, PGG, RGG, AGG, SGG, LGG, TGG, VGG, GGP, GGR, GGA, GGS, GGL, GGT, GGV, D, E, F, H, I, K, M, Q, W, Y, AR, AS, AT, AY, DL, DT, EA, EK, FH, FS, HL, HW, IS, KV, LD, LE, LR, LS, LT, NR, NT, QE, QL, QT, RA, RD, RE, RF, RH, RL, RR, RS, RV, SA, SD, SE, SF, SI, SK, SL, SQ, SR, SS, ST, SV, TA, TR, TS, TT, TW, VD, VS, WS, YS, AAE, AYH, DTL, EKR, ISR, NTP, PKS, PRP, PTA, PTQ, REL, RPL, SAA, SAL, SGL, SSE, TGL, WGT;
(iii) DH is all of a human CDRH3 DH amino acid sequence, wherein the DH amino acid sequence is selected from the group consisting of ATT, GAT, GIV, IVG, VGA, VLLLWLLL (SEQ ID NO: 239), ITMIVVVIT (SEQ ID NO: 240), VQWLV (SEQ ID NO: 241), VQQLV (SEQ ID NO: 242), VLRFLEWLLY (SEQ ID NO: 243), YYDFWSGYYT (SEQ ID NO: 244), WILYQLLC (SEQ ID NO: 245), LRL (SEQ ID NO: 246), TTVT (SEQ ID NO: 247), VWELL (SEQ ID NO: 248), VDTAMVT (SEQ ID NO: 249), WIQLWL (SEQ ID NO: 250), RILWWLLL (SEQ ID NO: 251), DIVVVVAAT (SEQ ID NO: 252), VLLLWFG (SEQ ID NO: 595), GATT (SEQ ID NO: 623), GIVG (SEQ ID NO: 624), IVGA (SEQ ID NO: 625), VGAT (SEQ ID NO: 626), GIVGA (SEQ ID NO: 627), IVGAT (SEQ ID NO: 628), VGATT (SEQ ID NO: 629), GIVGAT (SEQ ID NO: 630), IVGATT (SEQ ID NO: 631), GIVGATT (SEQ ID NO: 13), YSG, YSGS (SEQ ID NO: 632), YSGSY (SEQ ID NO: 633), YSGSYY (SEQ ID NO: 14), CSSTSC (SEQ ID NO: 622), CSSTSCY (SEQ ID NO: 620), YCSSTSC (SEQ ID NO: 621), CSSTSCYT (SEQ ID NO: 617), GYCSSTSC (SEQ ID NO: 618), YCSSTSCY (SEQ ID NO: 619), GYCSSTSCY (SEQ ID NO: 615), YCSSTSCYT (SEQ ID NO: 616), GYCSSTSCYT (SEQ ID NO:10), AAM, DIV, IVY, PAA, VPA, VVP, VVV, DIVV (SEQ ID NO: 634), IVVV (SEQ ID NO: 635), PAAM (SEQ ID NO: 636), VPAA (SEQ ID NO: 637, VVPA (SEQ ID NO: 638), VVVP (SEQ ID NO: 639), DIVVY (SEQ ID NO: 640), IVVVP (SEQ ID NO: 641), VPAAM (SEQ ID NO: 642), VVPAA (SEQ ID NO: 643), VVVPA (SEQ ID NO: 644), DIVVVP (SEQ ID NO: 645), IVVVPA (SEQ ID NO: 646), VVPAAM (SEQ ID NO: 647), VVVPAA (SEQ ID NO: 648), DIVVVPA (SEQ ID NO: 649), IVVVPAA (SEQ ID NO: 650), VVVPAAM (SEQ ID NO: 651), DIVVVPAA (SEQ ID NO: 652), IVVVPAAM (SEQ ID NO: 653), DIVVVPAAM (SEQ ID NO: 11), CSGGSC (SEQ ID NO: 654), CSGGSCY (SEQ ID NO: 655), YCSGGSC (SEQ ID NO: 656), CSGGSCYS (SEQ ID NO: 657), GYCSGGSC (SEQ ID NO: 658), YCSGGSCY (SEQ ID NO: 659), GYCSGGSCY (SEQ ID NO: 660), YCSGGSCYS (SEQ ID NO: 661), GYCSGGSCYS (SEQ ID NO: 16), FGV, GVV, IFG, ITI, TIF, VVI, FGVV (SEQ ID NO: 662) , GVVI (SEQ ID NO: 663), IFGV (SEQ ID NO: 664), ITIF (SEQ ID NO: 665) , TIFG (SEQ ID NO: 666), VVII (SEQ ID NO: 667), FGVVI (SEQ ID NO: 668), GVVII (SEQ ID NO: 669), IFGVV (SEQ ID NO: 670), ITIFG (SEQ ID NO: 671), TIFGV (SEQ ID NO: 672), FGVVII (SEQ ID NO: 673), IFGVVI (SEQ ID NO: 674), ITIFGV (SEQ ID NO: 675), TIFGVV(SEQ ID NO: 676), IFGVVII (SEQ ID NO: 677), ITIFGVV (SEQ ID NO: 678), TIFGVVI (SEQ ID NO: 679), ITIFGVVI (SEQ ID NO: 680), TIFGVVII(SEQ ID NO: 681), ITIFGVVII (SEQ ID NO: 9), ELL, FGE, GEL, LLW, LWF, VLL, WFG, FGEL (SEQ ID NO: 682), GELL (SEQ ID NO: 683), LLWF (SEQ ID NO: 684), LWFG (SEQ ID NO: 685), VLLW (SEQ ID NO: 686), WFGE (SEQ ID NO: 687), FGELL (SEQ ID NO: 688), LLWFG (SEQ ID NO: 689), LWFGE (SEQ ID NO: 690), VLLWF (SEQ ID NO: 691), WFGEL (SEQ ID NO: 692), LLWFGE (SEQ ID NO: 693), LWFGEL (SEQ ID NO: 694), VLLWFG (SEQ ID NO: 695), WFGELL (SEQ ID NO: 696), LLWFGEL (SEQ ID NO: 697), LWFGELL (SEQ ID NO: 698), VLLWFGE (SEQ ID NO: 699), LLWFGELL (SEQ ID NO: 700), VLLWFGEL (SEQ ID NO: 701), VLLWFGELL (SEQ ID NO: 1), GSG, GSY, SGS, SYY, YGS, YYG, YYN, YYY, GSGS (SEQ ID NO: 702), GSYY (SEQ ID NO: 703), SGSY (SEQ ID NO: 704) , SYYN (SEQ ID NO: 705), YGSG (SEQ ID NO: 706), YYGS (SEQ ID NO: 707), YYYG (SEQ ID NO: 708), GSGSY (SEQ ID NO: 709), GSYYN (SEQ ID NO: 710), SGSYY (SEQ ID NO: 711), YGSGS (SEQ ID NO: 712), YYGSG (SEQ ID NO: 713), YYYGS (SEQ ID NO: 714), GSGSYY (SEQ ID NO: 715), SGSYYN (SEQ ID NO: 716), YGSGSY (SEQ ID NO: 717), YYGSGS (SEQ ID NO: 718), YYYGSG (SEQ ID NO: 719), GSGSYYN (SEQ ID NO: 720), YGSGSYY (SEQ ID NO: 721), YYGSGSY (SEQ ID NO: 722), YYYGSGS (SEQ ID NO: 723), YGSGSYYN (SEQ ID NO: 724), YYGSGSYY (SEQ ID NO: 725), YYYGSGSY (SEQ ID NO: 726), YYGSGSYYN (SEQ ID NO: 727), YYYGSGSYY (SEQ ID NO: 728), YYYGSGSYYN (SEQ ID NO: 2), GVI, ITM, MVR, RGV, TMV, VII, VRG, GVII (SEQ ID NO: 729), ITMV (SEQ ID NO: 730), MVRG (SEQ ID NO: 731), RGVI (SEQ ID NO: 732), TMVR (SEQ ID NO: 733), VRGV (SEQ ID NO: 734), ITMVR (SEQ ID NO: 735), MVRGV (SEQ ID NO: 736), RGVII (SEQ ID NO: 737), TMVRG (SEQ ID NO: 738), VRGVI (SEQ ID NO: 739), ITMVRG (SEQ ID NO: 740), MVRGVI (SEQ ID NO: 741), TMVRGV (SEQ ID NO: 742), VRGVII (SEQ ID NO: 743), ITMVRGV (SEQ ID NO: 744), MVRGVII (SEQ ID NO: 745), TMVRGVI (SEQ ID NO: 746), ITMVRGVI (SEQ ID NO: 747), TMVRGVII (SEQ ID NO: 748), ITMVRGVII (SEQ ID NO: 3), DSS, GYY, SGY, SSG, YDS, YYD, DSSG (SEQ ID NO: 749), GYYY (SEQ ID NO: 750), SGYY (SEQ ID NO: 751), SSGY (SEQ ID NO: 752), YDSS (SEQ ID NO: 753), YYDS (SEQ ID NO: 754), YYYD (SEQ ID NO: 755), DSSGY (SEQ ID NO: 756), SGYYY (SEQ ID NO: 757), SSGYY (SEQ ID NO: 758), YDSSG (SEQ ID NO: 759), YYDSS (SEQ ID NO: 760), YYYDS (SEQ ID NO: 761), DSSGYY (SEQ ID NO: 762), SSGYYY (SEQ ID NO: 763, YDSSGY (SEQ ID NO: 764), YYDSSG (SEQ ID NO: 765), YYYDSS (SEQ ID NO: 766), DSSGYYY (SEQ ID NO: 767), YDSSGYY (SEQ ID NO: 768), YYDSSGY (SEQ ID NO: 769), YYYDSSG (SEQ ID NO: 770), YDSSGYYY (SEQ ID NO: 771), YYDSSGYY (SEQ ID NO: 772), YYYDSSGY (SEQ ID NO: 773), YYDSSGYYY (SEQ ID NO: 774), YYYDSSGYY (SEQ ID NO: 775), YYYDSSGYYY (SEQ ID NO: 4), DYG, GDY, YGD, DYGD (SEQ ID NO: 613), YGDY (SEQ ID NO: 614), DYGDY (SEQ ID NO: 12), SYG, YGY, YSY, GYSY (SEQ ID NO: 776), SYGY (SEQ ID NO: 777), YSYG (SEQ ID NO: 778), GYSYG (SEQ ID NO: 779), YSYGY (SEQ ID NO: 780), GYSYGY (SEQ ID NO: 15), SSS, SSW, SWY, SSSW (SEQ ID NO: 781), SSWY (SEQ ID NO: 782), YSSS (SEQ ID NO: 783), GYSSS (SEQ ID NO: 784), SSSWY (SEQ ID NO: 785), YSSSW(SEQ ID NO: 786), GYSSSW (SEQ ID NO: 787), YSSSWY (SEQ ID NO: 788), GYSSSWY (SEQ ID NO: 7) , GWY, GYS, SGW, YSS, GYSS (SEQ ID NO: 789), SGWY (SEQ ID NO: 790), SSGW (SEQ ID NO: 791), YSSG (SEQ ID NO: 792), GYSSG (SEQ ID NO: 793), SSGWY (SEQ ID NO: 794), YSSGW (SEQ ID NO: 795), GYSSGW (SEQ ID NO: 796), YSSGWY (SEQ ID NO: 797), GYSSGWY (SEQ ID NO: 5), AVA, GIA, IAV, VAG, AVAG (SEQ ID NO: 798), GIAV (SEQ ID NO: 799), IAVA (SEQ ID NO: 800), GIAVA (SEQ ID NO: 801), IAVAG (SEQ ID NO: 802), GIAVAG (SEQ ID NO: 6), AAA, AAG, IAA, AAAG (SEQ ID NO: 803), GIAA (SEQ ID NO: 804), IAAA (SEQ ID NO: 805), GIAAA (SEQ ID NO: 806), IAAAG (SEQ ID NO: 807), and GIAAAG (SEQ ID NO: 8);
(iv) N2 is an amino acid sequence selected from the group consisting of G, P, R, A, S, L, T, V, GG, GP, GR, GA, GS, GL, GT, GV, PG, RG, AG, SG, LG, TG, VG, PP, PR, PA, PS, PL, PT, PV, RP, AP, SP, LP, TP, VP, IG, KG, GW, FP, EG, GGG, GPG, GRG, GAG, GSG, GLG, GTG, GVG, PGG, RGG, AGG, SGG, LGG, TGG, VGG, GGP, GGR, GGA, GGS, GGL, GGT, GGV, D, E, F, H, I, K, M, Q, W, Y, AR, AS, AT, AY, DL, DT, EA, EK, FH, FS, HL, HW, IS, KV, LD, LE, LR, LS, LT, NR, NT, QE, QL, QT, RA, RD, RE, RF, RH, RL, RR, RS, RV, SA, SD, SE, SF, SI, SK, SL, SQ, SR, SS, ST, SV, TA, TR, TS, TT, TW, VD, VS, WS, YS, AAE, AYH, DTL, EKR, ISR, NTP, PKS, PRP, PTA, PTQ, REL, RPL, SAA, SAL, SGL, SSE, TGL, WGT;
(v) H3-JH is all of a human CDRH3 H3-JH amino acid sequence, wherein the H3-JH amino acid sequence is selected from the group consisting of AEYFQH (SEQ ID NO: 17), EYFQH (SEQ ID NO: 583), YFQH (SEQ ID NO: 584), FQH, QH, H YWYFDL (SEQ ID NO: 18), WYFDL (SEQ ID NO: 585), YFDL (SEQ ID NO: 586), FDL, DL, L, AFDV (SEQ ID NO: 19), FDV, DV, V, YFDY (SEQ ID NO: 20), FDY, DY, Y, NWFDS (SEQ ID NO: 21), WFDS (SEQ ID NO: 587), FDS, DS, S, YYYYYGMDV (SEQ ID NO: 22), YYYYGMDV (SEQ ID NO: 588), YYYGMDV (SEQ ID NO: 589), YYGMDV (SEQ ID NO: 590), YGMDV (SEQ ID NO: 591), GMDV (SEQ ID NO: 592), MDV, AFDI (SEQ ID NO: 852), FDI, DI, NWFDP (SEQ ID NO: 857), WFDP (SEQ ID NO: 858), FDP, and DP;
wherein the diversity of the polynucleotides encoding the at least about 106 unique antibody CDRH3 amino acid sequences is created by each of the polynucleotides having a CDRH3 sequence that is different from the CDRH3 sequence of every other polynucleotide;
wherein the antibody heavy chain is a variable domain with framework (FRM) and complementary determining regions (CDR) comprising FRMH1-CDRH1-FRM2-CDRH2-FRMH3-CDRH3-FRMH4; and
a VKCDR3 amino acid sequence comprising about 1 to about 10 of the amino acids found at Kabat positions 89, 90, 91, 92, 93, 94, 95, 95A, 96, and 97, in selected VKCDR3 amino acid sequences derived from a particular IGKV or IGKJ germline sequence;
wherein the antibody light chain is a variable domain with framework (FRM) and complementary determining regions (CDR) comprising FRMVK1-VKCDR1-FRMVK2-VKCDR2-FRMVK3-VKCDR3-FRMVK4.

US Pat. No. 10,189,861

PYRIMIDO-DIAZEPINONE COMPOUNDS AND METHODS OF TREATING DISORDERS

DANA-FARBER CANCER INSTIT...

1. A compound having the formula:
or a pharmaceutically acceptable salt thereof,
wherein,
R? is H or methyl;
L is absent, SO2, or CO;
X is H, methyl, fluoro, chloro, phenyl, pyridinyl, thiophenyl, —NH—CO—CH?CH—CH2—N(CH3)2, —S(O)2—N(CH3)2, or

Z is NH or N—C1-C3 alkyl;
R2 is hydrogen or methyl;
R6 is hydrogen; and
R1 is H, C?O(CH3),

US Pat. No. 10,189,857

POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

Vanderbilt University, N...

1. A compound of formula (I),
or a pharmaceutically acceptable salt thereof, wherein:
W is selected from CR1 and N;
X is selected from CR1 and N;
Y is selected from CR1 and N;
each R1 is independently selected from hydrogen and C1-C6 alkyl;
R2 is hydrogen or C1-C6 alkyl;
R3a and R3b are each independently selected from hydrogen and C1-C6 alkyl, or R3a and R3b are taken together with the nitrogen atom to which they are attached to form an optionally substituted ring;
R4a is hydrogen and R4b is selected from alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, heteroalkyl, heterocyclyl, and —(CRaRb)n—Z, any of which may be optionally substituted; or R4a and R4b, together with the nitrogen atom to which they are attached, are taken together to form an optionally substituted heterocyclic ring;
Ra is hydrogen;
Rb is hydrogen;
Z is selected from halo, —OR, —SR, —C(O)R, —C(O)OR, —S(O)R, —SO2R, —NR2, —C(O)NR2, —S(O)2NR2, aryl, heteroaryl, cycloalkyl, and heterocyclyl, any of which may be optionally substituted;
n is 1, 2, 3, 4, 5, 6, 7, or 8; and
each R is independently selected from the group consisting of hydrogen, alkyl, haloalkyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, heterocycle, heterocyclealkyl, heteroaryl, heteroarylalkyl, and heteroalkyl, any of which may be optionally substituted.

US Pat. No. 10,189,846

HEPATITIS B ANTIVIRAL AGENTS

ENANTA PHARMACEUTICALS, I...

1. A compound represented by Formula (I):
or a pharmaceutically acceptable salt thereof, wherein:
A is optionally substituted monocyclic heteroaryl;
B is hydrogen or methyl;
X is optionally substituted phenyl;
Y is optionally substituted phenyl or optionally substituted monocyclic heteroaryl; and
R and Z are taken together with the atoms to which they are attached to form an optionally substituted 4- to 12-membered heterocyclic.

US Pat. No. 10,189,830

ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS

BIOELECTRON TECHNOLOGY CO...

1. A compound of Formula I or Formula II:
wherein:
R1, R3 and R4 are independently C1-C6 alkyl or O—C1-C6 alkyl;
R2 is heteroaryl selected from the group consisting of benzoimidazole, benzothiazole, and benzoxazole, optionally substituted with one or two substituents independently selected from the group consisting of halo, —CH3, —CF3, —OCH3, and —C(O)—N(R5)(R6), wherein the substituents are independently linked to the heteroaryl by either a —C— or —N—within the heteroaryl; where the attachment point of the heteroaryl group to the rest of the molecule is either through a C or N in the rings;
R5 and R6 are independently selected from the group consisting of —H, —C1-C6 alkyl, and —C1-C6 alkyl-hydroxy, or wherein R5 and R6 together with the N to which they are attached form a saturated or unsaturated 3-8 membered ring, optionally incorporating one, two, or three additional heteroatoms each independently selected from the group consisting of N, O, and S, and wherein the ring is optionally substituted with —C1-C6 alkyl; and
z is 3;
or a stereoisomer, mixture of stereoisomers, solvate, hydrate, pharmaceutically acceptable salt or prodrug ester thereof.

US Pat. No. 10,189,829

INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

BIOGEN MA INC., Cambridg...

1. A compound represented by the following formula:
or a pharmaceutically acceptable salt thereof.

US Pat. No. 10,189,825

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

SUNOVION PHARMACEUTICALS ...

1. A compound of formula (I):
or a pharmaceutically acceptable salt thereof, wherein
X is selected from S and O;
one of R1a and R1b is

wherein
R5 is selected from hydrogen, alkyl, and C3-20 cycloalkyl;
R6 is selected from hydrogen, cyano, amino, alkylamino, alkyl, alkoxyl, alkenyl, alkynyl, C3-20 cycloalkyl, C3-20 cycloalkyl-C1-20 alkyl, C6-20 aryl, C6-20 aryl-C1-20 alkyl, C3-20 heterocyclyl with 1-2 heteroatoms selected from O, N, S, and combinations thereof, and C5-20 heteroaryl with 1-2 heteroatoms selected from O, N, S, and combinations thereof,
R7, and R8 are each independently selected from hydrogen, halo, cyano, amino, alkylamino, alkyl, alkoxyl, alkenyl, alkynyl, C3-20 cycloalkyl, C3-20 cycloalkyl-C1-20 alkyl, C6-20 aryl, C6-20 aryl-C1-20 alkyl, C3-20 heterocyclyl with 1-2 heteroatoms selected from O, N, S, and combinations thereof, and C5-20 heteroaryl with 1-2 heteroatoms selected from O, N, S, and combinations thereof;
and the other of R1a and R1b is selected from hydrogen, halo, cyano, alkyl, alkoxyl, alkenyl, alkynyl, C3-20 cycloalkyl, C3-20 cycloalkyl-C1-20 alkyl, C6-20 aryl, C6-20 aryl-C1-20 alkyl, C3-20 heterocyclyl with 1-2 heteroatoms selected from O, N, S, and combinations thereof, and C5-20 heteroaryl with 1-2 heteroatoms selected from O, N, S, and combinations thereof; and
R2 and R3 and the atoms to which they are attached form a benzene ring,
wherein each amino, alkylamino, alkyl, alkoxyl, alkenyl, alkynyl, C3-20 cycloalkyl, C3-20 cycloalkyl-C1-20 alkyl, C6-20 aryl, benzene ring, C6-20 aryl-C1-20 alkyl, C3-20 heterocyclyl, and C5-20 heteroaryl thereof is optionally substituted.

US Pat. No. 10,189,815

2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME

NIHON MEDI-PHYSICS CO., L...

1. A compound represented by the following general formula (1) or a salt thereof:
wherein R1 represents a hydrogen atom or CO2Ra, R2 represents a hydrogen atom, a halogen atom or CO2Ra, R3 represents a hydrogen atom or a hydroxyalkyl group containing 1 to 10 carbon atoms, R4 represents a hydrogen atom, a hydroxy group or an alkoxy group containing 1 to 10 carbon atoms, R5 represents a linear alkyl group containing 1 to 5 carbon atoms in which a hydrogen atom is optionally replaced by a halogen atom, a cyclic alkyl group containing 3 to 5 carbon atoms in which a hydrogen atom is optionally replaced by a halogen atom, a hydroxyalkyl group containing 1 to 5 carbon atoms, or an o-, p- or m-halobenzyl group, A represents CH or a nitrogen atom, X1 and X3 each independently represent a hydrogen atom or a halogen atom, X2 represents a hydrogen atom, a halogen atom or a nitrile group, provided that at least one of X1, X2 and X3 represents a halogen atom, and each Ra independently represents an alkyl group containing 1 to 10 carbon atoms.

US Pat. No. 10,189,805

METABOLISM PROBES FOR THERAPY AND DIAGNOSIS

Vanderbilt University, N...

1. A compound of the following formula:wherein:R1 is a bond, optionally substituted C1-C6 alkyl, or optionally substituted —(C1-C6 alkyl)—SO2—R2;
R2 is optionally substituted and chosen from morpholino, pyrrolidine, pyrrole, piperidine, pyridine, benzoimidazole, benzothiazole, piperazine, methyl-piperazine;
R3 is H or optionally substituted C1-C6 alkyl; and
R4 is NH2 or NHBoc;or pharmaceutically acceptable salts thereof.

US Pat. No. 10,189,804

METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND

DAIICHI SANKYO COMPANY, L...

1. A method for producing a compound represented by formula (13) or a pharmacologically acceptable salt thereof, the method comprising:(i) a step of
1) reacting a compound represented by formula (10) or a compound represented by formula (11) with 3-(chlorosulfonyl)benzoyl chloride in a solvent to obtain a condensate, and then
2) reacting the condensate with a compound represented by formula (3) in a solvent in the presence of a base to produce a compound represented by formula (12):
wherein R1 represents a C1-C6 alkyl group, R2 represents a C1-C6 alkyl group, R3 represents a C1-C6 alkyl group, and HX represents an acid; and(ii) a step of subjecting the compound represented by formula (12) produced in the previous step to a hydrolysis reaction in the presence of aqueous alkali in a solvent to produce a compound represented by formula (13):
wherein R1 represents a C1-C6 alkyl group, R2 represents a C1-C6 alkyl group, and R3 represents a C1-C6 alkyl group.

US Pat. No. 10,189,799

PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES

BAYER CROPSCIENCE AKTIENG...

1. Process for preparing one or more phenylisoxazoline derivatives of formula (I)
wherein
R1 is methyl, bromomethyl or chloromethyl;
R2 is halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkyl and
R3 is C1-C4-alkylsulphonyloxy, C1-C4-haloalkylsulphonyloxy,
wherein, in (i), a chloroxime of formula (II)

wherein R4 is C1-C12-alkyl,
is reacted with a styrene of formula (III)

wherein R2 and R3 are as defined above,
in the presence of an inorganic base in an organic aprotic solvent to give the corresponding phenylisoxazoline of formula (IV)

wherein R2, R3 and R4 are as defined above,
and the latter then reacts, in (ii), with an organometallic reagent and an organic base in an organic aprotic solvent to give the ketone of formula (Ia)

wherein R2 and R3 are as defined above,
and then, in (iii), in the presence of a halogenating agent in a solvent, the haloketone of formula (Ib) is formed

wherein R2 and R3 are as defined above and
X is chlorine or bromine.

US Pat. No. 10,189,794

HETEROARYL COMPOUNDS AND USES THEREOF

Celgene CAR LLC, Pembrok...

1. A method for inhibiting activity of FGFR4, or a mutant thereof, in a patient or biological sample, comprising the step of administering to said patient or biological sample a compound of formula I:
or a pharmaceutically acceptable salt thereof, wherein:
X1 is —NR4, N, —CR4R4?, or —CR4;
X2 is —NR5, N, —CR5R5?, or —CR5;
X3 is N or CR6
X4 is N or CR7;
X5 is N, C, or CH; wherein at least one of X1, X2, X3, X4, or X5 is N;
G is H, O, OR, or N(R)(R);
Ring A is an optionally substituted group selected from a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 4-7 membered saturated or partially unsaturated heterocyclic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 7-10 membered bicyclic saturated, partially unsaturated or aryl ring;
each R is independently hydrogen or an optionally substituted group selected from C1-6 aliphatic, phenyl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 4-7 membered heterocyclic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or
two R groups on the same nitrogen are taken together with the nitrogen atom to which they are attached to form a 4-7 membered heterocyclic ring having 0-2 additional heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 4-7 membered heteroaryl ring having 0-4 additional heteroatoms independently selected from nitrogen, oxygen, or sulfur;
R1 is a warhead group -L-Y; wherein R1 is attached to an atom adjacent to the atom where T is attached, wherein:
orL is a bivalent C2-8 straight or branched, hydrocarbon chain wherein L has at least one double bond and one or two methylene units of L are optionally and independently replaced by —NRC(O)—, —C(O)NR—, —N(R)SO2—, —SO2N(R)—, —S—, —S(O)—, —SO2—, —OC(O)—, —C(O)O—, cyclopropylene, —O—, —N(R)—, or —C(O)—; or
L is a bivalent C2-8 straight or branched, hydrocarbon chain wherein L has at least one alkylidenyl double bond and at least one methylene unit of L is replaced by —C(O)—, —NRC(O)—, —C(O)NR—, —N(R)SO2—, —SO2N(R)—, —S—, —S(O)—, —SO2—, —OC(O)—, or —C(O)O—, and one additional methylene unit of L is optionally replaced by cyclopropylene, —O—, —N(R)—, or —C(O)—; or
L is a bivalent C2-8 straight or branched, hydrocarbon chain wherein one methylene unit of L is replaced by cyclopropylene and one additional methylene unit of L is replaced by —NRC(O)—, —C(O)NR—, —N(R)SO2—, —SO2N(R)—, —S—, —S(O)—, —SO2—, —OC(O)—, or —C(O)O—; or
L is a bivalent C2-8 straight or branched, hydrocarbon chain wherein L has at least one triple bond and one or two methylene units of L are optionally and independently replaced by —NRC(O)—, —C(O)NR—, —N(R)SO2—, —SO2N(R)—, —S—, —S(O)—, —SO2—, —OC(O)—, or —C(O)O—; and
the Y group of R1 is hydrogen, C1-6 aliphatic optionally substituted with oxo, halogen, NO2, or CN, or a 3-10 membered monocyclic or bicyclic, saturated, partially unsaturated, or aryl ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, and wherein said ring is substituted with 1-4 Re groups; or
L is a covalent bond, —CH2—, —NH—, —C(O)—, —CH2NH—, —NHCH2—, —NHC(O)—, —NHC(O)CH2OC(O)—, —CH2NHC(O)—, —NHSO2—, —NHSO2CH2—, or —SO2NH—, and the Y group of R1 is selected from:
(i) C1-6 alkyl substituted with oxo, halogen, NO2, or CN; or
(ii) C2-6 alkenyl substituted with oxo, halogen, NO2, or CN; or
(iii) C2-6 alkynyl optionally substituted with oxo, halogen, NO2, or CN; or
(iv) a saturated 3-4 membered heterocyclic ring having 1 heteroatom selected from oxygen or nitrogen wherein said ring is substituted with 1-2 Re groups; or
(v) a saturated 5-6 membered heterocyclic ring having 1-2 heteroatom selected from oxygen or nitrogen wherein said ring is substituted with 1-4 Re groups; or
(vi)

 or
(vii) a saturated 3-6 membered carbocyclic ring, wherein said ring is substituted with 1-4 Re groups; or
(viii) a partially unsaturated 3-6 membered monocyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-4 Re groups; or
(ix) a partially unsaturated 3-6 membered carbocyclic ring, wherein said ring is substituted with 1-4 Re groups; or
(x)

 or
(xi) a partially unsaturated 4-6 membered heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-4 Re groups; or
(xii)

 or
(xiii) a 6-membered aromatic ring having 0-2 nitrogens wherein said ring is substituted with 1-4 Re groups; or
(xiv)

 or
(xv) a 5-membered heteroaryl ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-3 Re groups; or
(xvi)

 or
(xvii) an 8-10 membered bicyclic, saturated 3-4 membered heterocyclic, or aryl ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-4 Re groups; or
L is a covalent bond, —C(O)—, —N(R)C(O)—, or a bivalent C1-8 saturated or unsaturated, straight or branched, hydrocarbon chain; and the Y group of R1 is selected from:
(i) C1-6 alkyl substituted with oxo, halogen, NO2, or CN; or
(ii) C2-6 alkenyl optionally substituted with oxo, halogen, NO2, or CN; or
(iii) C2-6 alkynyl optionally substituted with oxo, halogen, NO2, or CN; or
(iv) a saturated 3-4 membered heterocyclic ring having 1 heteroatom selected from oxygen or nitrogen wherein said ring is substituted with 1-2 Re groups; or
(v) a saturated 5-6 membered heterocyclic ring having 1-2 heteroatom selected from oxygen or nitrogen wherein said ring is substituted with 1-4 Re groups; or
(vi)

 or
(vii) a saturated 3-6 membered carbocyclic ring, wherein said ring is substituted with 1-4 Re groups; or
(viii) a partially unsaturated 3-6 membered monocyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-4 Re groups; or
(ix) a partially unsaturated 3-6 membered carbocyclic ring, wherein said ring is substituted with 1-4 Re groups; or
(x)

 or
(xi) a partially unsaturated 4-6 membered heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-4 Re groups; or
(xii)

 or
(xiii) a 6-membered aromatic ring having 0-2 nitrogens wherein said ring is substituted with 1-4 Re groups; or
(xiv)

 or
(xv) a 5-membered heteroaryl ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-3 Re groups; or
(xvi)

 or
(xvii) an 8-10 membered bicyclic, saturated, partially unsaturated, or aryl ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein said ring is substituted with 1-4 Re groups;
each Re is independently selected from -Q-Z, oxo, NO2, halogen, CN, C1-6 aliphatic optionally substituted with oxo, halogen, NO2, or CN, or a suitable leaving group selected from alkoxy, sulphonyloxy, optionally substituted alkylsulphonyloxy, optionally substituted alkenylsulfonyloxy, optionally substituted arylsulfonyloxy, acyl, or diazonium, wherein:
Q is a bivalent C1-6 saturated or unsaturated, straight or branched, hydrocarbon chain, wherein one or two methylene units of Q are optionally and independently replaced by —N(R)—, —S—, —O—, —C(O)—, —OC(O)—, —C(O)O—, —SO—, —SO2—, —N(R)C(O)—, —C(O)N(R)—, —N(R)SO2—, or —SO2N(R)—; and
each Z is independently hydrogen or C1-6 aliphatic substituted with oxo, halogen, NO2, or CN;
each R2 is independently —R, halogen, -haloalkyl, —OR, —SR, —CN, —NO2, —SO2R, —SOR, —C(O)R, —CO2R, —C(O)N(R)2, —NRC(O)R, —NRC(O)N(R)2, —NRSO2R, or —N(R)2;
R3 is hydrogen, C2-6 alkenyl, —W-Cy, or C1-6 alkyl, wherein the C1-6 alkyl is optionally substituted with 1-3 groups independently selected from halogen, —CN, oxo, —OR?, or —C(O)O(C1-6 alkyl);
W is absent or is a bivalent C1-3 alkylene chain optionally substituted with one or more R? and
wherein one methylene unit of W is optionally replaced with —O—, —S—, or —NR?—;
each R? is independently hydrogen or C1-6 alkyl;
each R? is independently halogen or C1-6 alkyl, wherein the C1-6 alkyl is optionally substituted with 1-3 groups independently selected from halogen, —CN, oxo, or —OR?;
Cy is phenyl, C3-7 cycloalkyl, or a 3-7 membered monocyclic or 5-10 membered bicyclic saturated, partially unsaturated, or heteroaryl ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, wherein Cy is optionally substituted with 1-3 Rx;
each Rx is independently H, —CN, oxo, —NH2, C1-6 alkyl, halogen, —OR?, —N(R?)2, —NHC(O)(C1-6 alkyl), —C(O)N(R?)2, —C(O)O(C1-6 alkyl), —NHSO2(C1-6 alkyl), or —SO2N(R?)2;
or R3 is absent if not allowed by valence;
each of R4 and R4? is independently hydrogen or an optionally substituted group selected from C1-6 aliphatic, phenyl, a 3-8 membered saturated or partially unsaturated carbocyclic ring which is optionally bridged, a 4-7 membered heterocyclic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 7-10 membered bicyclic saturated, partially unsaturated or aryl ring, which is optionally bridged;
each of R5 and R5? is independently —R, halogen, —OR, —SR, —CN, —NO2, —SO2R, —SOR, —C(O)R, —CO2R, —C(O)N(R)2, —NRC(O)R, —NRC(O)N(R)2, —NRSO2R, or —N(R)2;
Y is O or NRa?;
Ra is hydrogen or an optionally substituted C1-6 aliphatic group;
T is a covalent bond or a bivalent straight or branched, saturated or unsaturated C1-6 hydrocarbon chain wherein one or more methylene units are optionally replaced by —O—, —S—, —N(R)—, —C(O)—, —OC(O)—, —C(O)O—, —C(O)N(R)—, —N(R)C(O)—, —N(R)C(O)N(R)—, —S(O)—, —SO2—, —SO2N(R)—, —N(R)SO2—, or —N(R)SO2N(R)—;
q is 0-6; and
each of R6 and R7 is independently —R, halogen, —OR, —SR, —CN, —NO2, —SO2R, —SOR, —C(O)R, —CO2R, —C(O)N(R)2, —NRC(O)R, —NRC(O)N(R)2, —NRSO2R, or —N(R)2.

US Pat. No. 10,189,744

USE OF AN EPOXIDE-AMINE-BASED MULTICOMPONENT MORTAR COMPOSITION

Hilti Aktiengesellschaft,...

1. A multicomponent mortar composition comprising a hybrid hardener which contains a mixture of(i) at least one amine, selected from among aliphatic, alicyclic and aromatic amines, wherein the amine on average has at least two reactive hydrogen atoms, bonded to a nitrogen atom, per molecule, as a hardener;
(ii) a novolac resin of formula (I):

in which R1, R2, R3 and R4, each independent of each other, are hydrogen or an unbranched or branched C1-C15 alkyl radical and n is 1 to 12, wherein the novolac resin is contained in a quantity of 30 to 45 percent by weight, relative to the total weight of the hybrid hardener (i) and (ii), as a catalyst; and
(iii) a compound of formula (II):

in which R1 is hydrogen or an unbranched or branched C1-C15 alkyl radical, R2 is a (CH2)nNR5R6 radical or a NH(CH2)nNR5R6 radical, in which R5 and R6 independently of each other are an unbranched or branched C1-C15 alkyl radical and n is 0 or 1, R3 and R4 independently of each other are hydrogen or a (CH2)nNR7R8 radical or a NH(CH2)nNR7R8 radical, and R7 and R8 independently of each other are an unbranched or branched C1-C15 alkyl radical and n is 0 or 1,
wherein the multicomponent mortar composition is epoxide-based, and
wherein the multicomponent mortar composition chemically fastens structural elements and anchoring means.

US Pat. No. 10,189,719

PROCESS FOR THE MANUFACTURE OF LITHIUM METAL OXIDE CATHODE MATERIALS

Nano One Materials Corp.,...

1. A process for forming a precursor to a lithium metal oxide comprising:providing lithium bicarbonate in a first aqueous mixture;
reacting said lithium bicarbonate with metal acetate thereby forming a second aqueous mixture comprising metal carbonate, lithium acetate, acetic acid and water;
neutralizing said acetic acid in said second aqueous mixture with lithium hydroxide thereby forming a third mixture comprising metal carbonate and lithium acetate;
separating said third mixture into a fourth mixture and a fifth mixture wherein said fourth mixture comprises said metal carbonate and a first portion of said lithium acetate with said metal carbonate and said lithium acetate being in a predetermined molar ratio, and said fifth mixture comprises a second portion of said lithium acetate; and
drying said fourth mixture thereby forming said precursor comprising metal carbonate and lithium acetate in said predetermined molar ratio.

US Pat. No. 10,189,694

YEAST-CREAM-DOSING DEVICE AND METHOD

LESAFFRE ET CIE, Paris (...

23. A device for dosing of stable bakers' yeast cream in a bakery, said device comprising:a piece of furniture provided with a refrigerated compartment having an internal temperature regulated at between ?2° C. and 12° C.;
an interchangeable transport reservoir located in the refrigerated compartment and containing stable yeast cream, said reservoir having a total internal volume of between 1 and 100 liters, and an outlet opening for the yeast cream;
an outlet conduit for dosing of the yeast cream, said conduit connecting the outlet opening of the interchangeable transport reservoir to a dispensing opening outside the refrigerated chamber; and
an opening/closing mechanism for the outlet conduit, enabling the opening of the outlet conduit for the dispensing of the yeast cream and enabling the closure of the outlet conduit in order to stop the dispensing of the yeast cream,
said device permitting the dispensing of a dosed quantity of yeast cream from the interchangeable transport reservoir via the dispensing opening,
wherein said interchangeable transport reservoir is a collapsible bag that permits the dispensing of a dosed quantity of yeast cream via the dispensing opening by activation of the opening/closing mechanism without entry of gas from outside the collapsible bag into the collapsible bag.

US Pat. No. 10,189,688

WINCH DRUM WITH INTERNAL WIRE STORAGE

NATIONAL OILWELL VARCO NO...

1. A winch drum device comprising:a first winch drum having a central axis of rotation and a radially outer surface configured to accommodate a plurality of axially displaced turns of wire rope;
an annular recess extending radially inward from the radially outer surface of the first winch drum and extending about the circumference of the radially outer surface of the first winch drum;
wherein the annular recess is configured to accommodate one or more turns of the wire rope and the first winch drum is configured to rotate about the central axis of rotation to pay in and pay out the wire rope from the annular recess.

US Pat. No. 10,189,667

POST-PROCESSING APPARATUS AND IMAGE FORMING APPARATUS INCLUDING SAME

HP PRINTING KOREA CO., LT...

1. A post-processing apparatus couplable to an image forming apparatus comprising:a paper discharging roller to
convey, from a conveying path, a first paper discharged from the image forming apparatus to a standby path connected to the conveying path,
convey the first paper from the standby path and a second paper sequentially discharged from the image forming apparatus from the conveying path, to an intermediate loading part, in a state in which a leading end of the first paper toward the intermediate loading part protrudes more than a leading end of the second paper toward the intermediate loading part;
a main paddle part to convey the first paper and the second paper conveyed to the intermediate loading part to a compiling region;
a reverse roller arranged at a lower side of the main paddle part to convey, along with the main paddle part, the first paper and the second paper to the compiling region; and
a binding part to process the first paper and the second paper conveyed to the compiling region.

US Pat. No. 10,189,662

MEDIUM SUPPLYING APPARATUS

PFU Limited, Ishikawa (J...

1. A medium supplying apparatus comprising:a separator roller configured to convey media to a downstream side in a conveying direction by being driven to rotate in the conveying direction in which the media are conveyed;
a retard roller that is disposed to face the separator roller and is configured to be driven to rotate in a direction opposite to the conveying direction while applying a predetermined conveying load to the media through a torque control mechanism;
a double feed detecting sensor that is disposed on a downstream side of the separator roller and the retard roller in the conveying direction and is configured to detect a double feed of the media; and
a control unit configured to
convey, by the separator roller, the media to the downstream side in the conveying direction;
detect, by the double feed detecting sensor, a double feed of the media while conveying the media to the downstream side in the conveying direction;
stop, in response to detecting the double feed of the media, rotation drive of the separator roller;
convey, by the retard roller, a part of the media to an upstream side in the conveying direction; and
check, by the double feed detecting sensor, for the double feed of the media repeatedly until the media is determined to become one sheet while the rotation drive of the separator roller is being stopped and the part of the media is being conveyed to the upstream side in the conveying direction,
wherein when the media is determined to become one sheet, the rotation drive of the separator roller is restarted,
wherein the retard roller conveys the part of the media to the upstream side in the conveying direction while awaiting a predetermined time td before restarting rotation drive of the separator, and
wherein the predetermined time td satisfies an expression of td?L0/Vre, wherein L0 represents a distance from where the separator roller and the retard roller come in contact each other to the double feed detecting sensor, and Vre represents a reverse peripheral speed of the retard roller when conveying the media in a conveying direction.

US Pat. No. 10,189,651

ITEM INFEED APPARATUS AND METHOD FOR A PALLETIZER

Top Tier, LLC, Clackamas...

1. A method of assembling rows of items in a palletizer, each item having a leading edge and a trailing edge, the method comprising the steps of:a. delivering a first item to a first conveyer;
b. engaging the trailing edge of the first item with a pusher and aligning the first item so that the trailing edge is parallel to the pusher;
c. delivering the first item with the pusher to a row accumulator wherein the row accumulator further comprises a second conveyer and the step of delivering the first item with the pusher to the row accumulator includes advancing the first item on the second conveyer to a desired position thereon; and
d. determining the position of the trailing edge of the first item on the row accumulator by detecting the position of the pusher.

US Pat. No. 10,189,641

STORAGE SYSTEM

Autostore Technology AS, ...

1. A storage system, comprisinga first grid structure of storage cells, each storage cell of the first grid structure being arranged to accommodate a vertical stack of storage bins, the first grid structure having a top level,
a first vehicle, arranged to move horizontally at the top level of the first grid structure, wherein the first vehicle is on top of rails that are provided in the top level of the first grid structure,
a second grid structur of storage cells, each storage cell of the second grid structure being arranged to accommodate a vertical stack of storage bins, the second grid structure being arranged at a different vertical level than the first grid structure,
a second vehicle, arranged to move horizontally at the top level of the second grid structure, wherein the second vehicle is on top of rails that are provided in the top level of the second grid structure,
a third grid structure of storage cells, each storage cell of the third grid structure being arranged to accommodate a vertical stack of storage bins, the third grid structure being arranged on a different vertical level than the first grid structure and the second grid structure,
a third vehicle, arranged to move horizontally at the top level of the third grid strucutre, wherein the third vehicle is on top of rails that are provided in the top level of the third grid structure,
a bin lift device, arranged to receive a bin from said vehicles and convey the bin, without said vehicles, in a vertical direction between the top levels of the first grid structure, the second grid structure, the third grid structure, and a delivery station,
wherein the first vehicle is further arranged to receive a storage bin from a storage cell at the top level of the first grid structure and to deliver the storage bin to the bin lift device, wherein the bin lift device is arranged to receive the storage bin from the first vehicle, and wherein the bin lift device is further arranged to convey the storage bin, without the first vehicle, in a vertical direction from the top level of the first grid structure to the delivery station,
wherein the second vehicle is further arranged to receive a storage bin from a storage cell at the top level of the second grid structure and to deliver the storage bin to the bin lift device, wherein the bin lift device is arranged to receive the storage bin from the second vehicle, and wherein the bin lift device is further arranged to convey the storage bin, without the second vehicle, in a vertical direction from the top level of the second grid structure to the delivery station,
wherein the third vehicle is further arranged to receive a storage bin from a storage cell at the top level of the third grid structure and to deliver the storage bin to the bin lift device, wherein the bin lift device is arranged to receive the storage bin from the third vehicle, and wherein the bin lift device is further arranged to convey the storage bin, without the third vehicle, in a vertical direction from the top level of the third grid structure to the delivery station, and
wherein the second grid structure is arranged below the first grid structure, and the third grid structure is arranged below the second grid structure.

US Pat. No. 10,189,597

FOOTED CONTAINER BASE

Amcor Rigid Plastics USA,...

1. A one-piece plastic container comprising:an upper portion defining an opening at an upper end of the container;
a cylindrical sidewall extending from the upper portion and defining a storage volume accessible through the opening; and
a base portion extending from the cylindrical sidewall to a base end of the container that is opposite to the upper end of the container, the base portion including:
a gate area at an axial center of the base portion;
a plurality of feet radially spaced apart about the axial center;
a plurality of straps, each one of the plurality of straps arranged between neighboring ones of the plurality of feet; and
a plurality of fillet areas, each one of the plurality of fillet areas arranged between one of the plurality of feet and straps on opposite sides thereof;
wherein the base portion includes a cumulative strap surface area defined by a total surface area of the plurality of straps, the gate area, and half a total surface area of the plurality of fillet areas, and a cumulative foot surface area defined by a total surface area of the plurality of feet and half the total surface area of the plurality of fillet areas;
wherein the base portion has a ratio of cumulative foot surface area to cumulative strap surface area in the range of 2.4-2.8:1;
wherein the base portion has a ratio of overall surface area to the cumulative strap surface area in the range of 3.4-3.8:1;
wherein the base portion has a ratio of overall surface area to the cumulative foot surface area of 1.2-1.6:1;
wherein about 67%-77% of an overall surface area of the base portion is the cumulative foot surface area; and
wherein about 23%-33% of the overall surface area of the base portion is the cumulative strap surface area.

US Pat. No. 10,189,580

IMAGE STABILIZATION AND POINTING CONTROL MECHANIZATION FOR AIRCRAFT IMAGING SYSTEMS

Aerobo, Brooklyn, NY (US...

1. An aircraft comprising:a platform;
a camera assembly rotatable relative to the platform and about three camera axes, the camera assembly comprising:
a camera; and
a mirror attached to the camera, wherein the mirror is rotatable relative to the camera and about a mirror axis, different from the three camera axes;
a first inertial measurement unit configured to measure inertial angles of the camera assembly; and
a second inertial measurement unit configured to measure inertial angles of the mirror.

US Pat. No. 10,189,566

3D COVERAGE MAPPING OF WIRELESS NETWORKS WITH UNMANNED AERIAL VEHICLES

ETAK Systems, LLC, Hunte...

8. An Air Traffic Control (ATC) system for Unmanned Aerial Vehicles (UAVs) supporting three-dimensional (3D) coverage mapping of a coverage area of a cell site, the ATC system comprising:a network interface and one or more processors communicatively coupled to one another, wherein the network interface is communicatively coupled to a plurality of UAVs via one or more wireless networks; and
memory storing instructions that, when executed, cause the one or more processors to provide the coverage area of the cell site to a UAV;
cause the UAV to fly about the coverage area at one or more elevations;
cause the UAV to take measurements of wireless performance during flight about the coverage area;
utilize the measurements to derive a 3D coverage map of the coverage area;
determine poor coverage areas in the 3D coverage map; and
cause performance of one or more remedial actions to address the poor coverage areas, wherein the one or more remedial actions comprise adding additional antennas on a cell tower at the cell site, adjusting antenna patterns of existing antennas on the cell tower, and adding a new cell tower in the coverage area, each of the one or more remedial actions is configured to increase coverage in the coverage area to address the poor coverage areas.

US Pat. No. 10,189,534

SUSPENSION CONTROL FOR A HUMAN-POWERED TWO-WHEELED VEHICLE AND METHOD

DT Swiss Inc., Grand Jun...

1. A chassis controller for an at least partially human-powered two-wheeled vehicle, comprising:a control device and at least one memory device connected to said control device;
at least one controllable shock absorber having two connecting units disposed to move relative to one another;
at least one sensor device for acquiring measurement data sets relating to a relative movement of said connecting units with respect to one another;
a filter device connected to said at least one sensor device and configured for pre-processing the measurement data sets;
wherein at least one data set, derived from a measurement data set acquired with said sensor device during the relative movement of said connecting units is stored in said memory device;
an analysis device connected to said memory device and configured to analyze at least one stored data set and to determine a filter parameter set based on an analysis result and to derive a control data set from the measurement data set with a filter parameter set; and
wherein said control device controls said shock absorber with the control data set.

US Pat. No. 10,189,520

MODULAR SYSTEM FOR A VEHICLE

Volkswagen Aktiengesellsc...

1. A modular system for a vehicle comprising:a selected instrument panel that extends over a width of an interior of the motor vehicle from a driver side of the vehicle to a passenger side of the vehicle;
at least one selected door that is arranged on a side of the vehicle in a pivotal manner in order to close or open a vehicle door opening adjoining the selected instrument panel;
wherein the modular system has at least two different instrument panels and/or at least two different doors for selection, wherein each instrument panel has a first joint region and each door has a second joint region,
wherein the second joint region is pivoted away from the first joint region when the at least one selected door is pivoted into an open position and the second joint region is pivoted towards the first joint region so as to adjoin the first joint region and form a unitary joint when the at least one selected door is pivoted into a closed position, and
wherein the second joint region corresponds to the first joint region such that each first joint region and each second joint region, when adjoined in the closed position of the door, always form the unitary joint with a same joint gap width therebetween.

US Pat. No. 10,189,514

AERODYNAMIC TRUCKING SYSTEMS

Strehl, LLC, Scottsdale,...

1. An aerodynamic fairing assembly for attachment to a trailer of a tractor-trailer comprising a top, bottom, front, rear, a pair of sides, wheels having tires and brakes, and a trailer frame comprising transverse structural support members extending between sides of the trailer, and having at least one rear wheel assembly situated below the trailer frame, the aerodynamic fairing assembly comprising:a side skirt fairing comprising an inner surface and an outer surface;
a transition located aft of the side skirt fairing;
a vented skirt fairing located aft of the transition comprising at least one longitudinal vent configured to allow air to flow therethrough, wherein the vented skirt fairing extends outwardly of a side of a trailer envelope to accommodate the wheels; and
one or more mounting brackets configured to couple the side skirt fairing, the transition, and the vented skirt fairing to one or more or of the transverse structural support members.

US Pat. No. 10,189,416

STORAGE COMPARTMENT FOR A VEHICLE INTERIOR TRIM

Volkswagen Aktiengesellsc...

1. A storage compartment for an interior trim of a vehicle, the storage compartment comprising:a storage-compartment bottom that transitions at an inner corner region into a side wall that is raised from the storage-compartment bottom; and
an insertion mat lining the storage-compartment bottom, the insertion mat forming a support surface for at least one small object, the insertion mat at least partially bounds at least one free deformation chamber, and when manual pressure via a fingertip is applied to the support surface, the insertion mat curves into the deformation chamber by arching such that between the deformed support surface and the object, an undercut for grasping under the object is accessible to the fingertips.

US Pat. No. 10,189,389

SYSTEM WITH A PIVOTABLE ARMREST AND A LOCKING AID

ADIENT LUXEMBOURG HOLDING...

1. A system comprising:a bracket device comprising a connecting element;
a pivotable armrest; and
a locking aid, wherein the armrest is articulated on the bracket device so as to be pivotable about a primary axis and can be transferred reversibly between a usage position and a stowage position via a transition position, wherein the armrest is connected rotationally conjointly to the connecting element, wherein the locking aid is arranged on the connecting element, wherein the locking aid is in frictionally engaging contact with the bracket device at a contact point or along a contact surface, wherein the locking aid is configured such that the frictionally engaging contact between the bracket device and the locking aid in a transition position is greater than that in the usage position or in the stowage position or both in the usage position and in the stowage position, the locking aid comprising a displaceable part, the displaceable part being displaceable relative to the connecting element along an offset direction, wherein a spring element is, at a first end, arranged substantially positionally fixedly relative to the connecting element, wherein the spring element is connected at a second end to the displaceable part, wherein the bracket element is configured such that the spacing between the first end of the spring element and the contact point or the contact surface is smaller in the transition position than in the usage position or stowage position.

US Pat. No. 10,189,373

SEAT ARRANGEMENT

ADIENT LUXEMBOURG HOLDING...

1. A seat arrangement, comprising:a first seat adjacent to a curb side of a vehicle with said first seat movable from a deployed position to a stored position;
a second seat;
a third seat, said first seat being smaller than each of said second seat and said third seat;
wherein said first seat is stored in said second seat in said stored position.

US Pat. No. 10,189,371

ELECTRICALLY-POWERED VEHICLE

SUBARU CORPORATION, Toky...

1. An electrically-powered vehicle, comprising:a high voltage battery configured to store electric power for travelling the electrically-powered vehicle;
a charger configured to output charge current to the high voltage battery, the charger including a first housing and a first circuit board accommodated in the first housing; and
a second housing including a first face, a second face opposed to the first face in a first direction, and a space defined between the first face and the second face that accommodates the high voltage battery,
wherein the first face comprises a low stiffness portion having stiffness lower than a stiffness of the second face, and
wherein the low stiffness portion is fastened to the charger at different locations that are disposed separately from each other in a second direction orthogonal to the first direction.

US Pat. No. 10,189,365

CHARGING CONTROL SYSTEM

TOYOTA JIDOSHA KABUSHIKI ...

1. A charging control system comprising:a vehicle configured to receive electric power from a residence and allow an in-vehicle electric storage device to be charged with the received electric power;
a monitoring device configured to monitor a use status of an electric appliance at the residence and a use status of the vehicle; and
a controller configured to:
identify the electric appliance correlated with the start of use of the vehicle based on the use status of the electric appliance monitored by the monitoring device and the use status of the vehicle;
learn a relationship between the use status of the identified electric appliance at the residence before a start of use of the vehicle and the use status of the vehicle;
estimate a start time of use of the vehicle based on the learned relationship and the use status of the identified electric appliance; and
calculate a charging start time based on the estimated start time of use of the vehicle and a required time to complete charging of the electric storage device, and provide an instruction to perform charging of the electric storage device;
wherein
the identified electric appliance includes a timer configured to preset a use time of the identified electric appliance, and
the controller is further configured to estimate the start time of use of the vehicle based on the use time preset in the identified electric appliance and the learned relationship.

US Pat. No. 10,189,360

ELECTRIC CHARGING SYSTEM

SUBARU CORPORATION, Toky...

1. An electric charging system that connects an electric charger and an electric vehicle via a charging cable and charges an electric storage device mounted on the electric vehicle, the electric charging system comprising:an electric charger, comprising:
a power converter configured to convert AC power received from an external power source to DC power, and comprising a positive electrode and a negative electrode electrically connected to two power supply lines, respectively,
a supply-side voltage sensor connected to the two power supply lines and configured to detect supply voltage values,
a charging controller comprising a supply-side processor communicable with a vehicle controller mounted on the electric vehicle and the supply-side voltage sensor, and
a housing accommodating the power converter, the supply-side voltage sensor, and the charging controller, and provided outside of and separately from the electric vehicle; and
a charging cable comprising:
a free edge including power supply connectors electrically connected to the power converter with the two power supply lines, the power supply connectors being connectable to charging connectors of the electric vehicle,
a fixed edge fixed to the housing, and
an elongated portion extended between the free edge and the fixed edge, and provided outside of and separately from the electric vehicle;
wherein the supply-side processor is configured to:
when the power supply connectors are connected to charging connectors of the electric vehicle, cause the electric charger to supply the DC power to the electric vehicle through the charging cable at detected supply voltage values, cause the electric vehicle to receive the DC power at receiving side voltage values, and receive the detected supply voltage values from the supply-side voltage sensor;
generate detected supply voltage data indicating a change of the detected supply voltage values with respect to time;
generate processed supply voltage data by subjecting the detected supply voltage data to a filtering process;
when the power supply connectors are connected to the charging connectors of the electric vehicle, communicate with the vehicle controller, and receive receiving side voltage data indicating a change of the receiving side voltages with respect to time from the vehicle controller;
by temporarily varying a change rate of the detected supply voltage values with respect to time, generate a first feature point corresponding the varying of the change rate in the processed supply voltage data at a first time, and generate a second feature point corresponding the varying of the change rate in the receiving side voltage data at a second time;
calculate a time lag between the first time and the second time;
calculate a voltage difference between the supply voltage and the receiving side voltage based on the time lag, the processed supply voltage data and the receiving side voltage data; and
cause the electric charger to terminate supplying the DC power to the electric vehicle after determining that a charge state of the electric vehicle has reached a determination value.

US Pat. No. 10,189,359

TRANSMITTING NOTIFICATION MESSAGES FOR AN ELECTRIC VEHICLE CHARGING NETWORK

CHARGEPOINT, INC., Campb...

1. A method performed on a charging station network server which manages a plurality of charging stations, the method comprising:receiving subscriber notification message preferences for a subscriber of electric vehicle charging service which indicate a set of one or more events of interest which the subscriber wishes to receive notification messages for, wherein at least one of the set of events of interest is charging session related;
receiving a set of one or more contact points associated with the subscriber;
authorizing the subscriber to use one of the plurality of charging stations;
receiving data associated with the subscriber from that one of the plurality of charging stations, the data indicating a charging session has been established for an electric vehicle associated with the subscriber; and
responsive to detecting the at least one of the set of the events of interest for the subscriber that is charging session related and which is related to the established charging session, transmitting a notification message for that event of interest to at least one of the set of contact points associated with the subscriber.

US Pat. No. 10,189,339

TONNEAU COVER SYSTEM FOR A CARGO BED OF A VEHICLE

Rugged Liner, Inc., Owos...

1. A tonneau cover system comprising:a first side rail;
a second side rail, where each of the first side rail and the second side rail are adapted to be mounted to a vehicle; and
a plurality of panels coupled to the first side rail and the second side rail, where the plurality of panels comprise:
a first panel;
a second panel spaced from said first panel;
a third panel adjacent said second panel;
a spacer bar disposed between said first panel and the second panel with said spacer bar being fixed to said first side rail and said second side rail, the spacer bar including a channel;
a mounting mechanism connected to the spacer bar, the mounting mechanism including:
a housing disposed within the channel of the spacer bar, the housing having an opening and a closed end;
a bracket pivotably connected to the housing so that the bracket is movable between a locked position where a portion of the bracket is located proximate to the closed end and a stowed position where a portion of the bracket is located within the opening;
wherein said first panel is pivotally coupled to said spacer bar to enable said first panel to pivot relative to said spacer bar while said spacer bar remains fixed to said first side rail and said second side rail;
wherein said third panel is pivotally coupled to said second panel to enable said third panel to pivot relative to said second panel and to permit said third panel to be located over said second panel while said spacer bar remains fixed to said side rails to define an intermediate folded position of said tonneau cover system; and
a hinge assembly mounted between said second panel and said spacer bar to enable said second panel and said third panels to pivot relative to said spacer bar as a unit from said intermediate folded position to a final folded position located over said spacer bar and a portion of said first panel while said spacer bar remains fixed to said first side rails and said second side rail.

US Pat. No. 10,189,334

REGISTER

TOYOTA JIDOSHA KABUSHIKI ...

1. A register comprising:a bezel having an air outlet formed therein;
a retainer having an air flow path along which an air flow toward the air outlet occurs and which communicates with the air outlet;
a movable fin for changing a blowout direction of air sent into the air flow path of the retainer and blown out from the air outlet, the movable fin having an upstream end and a downstream end;
a pair of rotational shafts for rotatably supporting the movable fin, the rotational shafts being formed at side ends of the movable fin and positioned at a downstream side along an air flow direction on the side ends; and
a fixed fin positioned near the air outlet of the bezel, the fixed fin having an upstream side and a downstream side;
wherein the downstream end of the movable fin is arranged near an edge position of the fixed fin positioned at the upstream side along the air flow direction, the downstream end and the edge position of the fixed fin being separated with a clearance therebetween,
wherein both upper and lower surfaces of the movable fin each include a concave surface which gradually curves from the upstream end to the downstream end, and
wherein a thickness of the movable fin narrows from the upstream end of the movable fin to a minimum thickness along the airflow direction at a position between the upstream end and the downstream end of the movable fin, and the thickness of the movable fin thickens from the minimum thickness from the position to the downstream end.

US Pat. No. 10,189,322

DEVICE FOR DISASSEMBLING A TIRE FROM A WHEEL RIM AND A METHOD OF DISASSEMBLING A TIRED WHEEL

BUTLER ENGINEERING AND MA...

1. A device for dismounting a tired wheel having a wheel rim and a tire mounted on the wheel rim, comprising:a support member,
a bill or lever-shaped disassembling tool having one end thereof articulated to said support member, and the other work end thereof substantially hook-shaped, whereby said disassembling tool can be angularly displaced between a first insertion position between the tire bead of the tire and edge of the wheel rim and a second engagement and extraction position of the tire bead,
comprising an interception element for holding said tool in an engagement and extraction position wherein the interception element is carried either by said support member or by said disassembling tool and arranged to intercept said tool or said support member, respectively, when said disassembling tool reaches said engagement and extraction position, said interception element comprising an elastically loaded pin, wherein during the angular displacement between said first insertion position and the second extraction position and upon reaching the second extraction position, the elastically loaded pin is energized to lock said tool in said second extraction position, and thereby preventing any backwards angular movement of said tool.

US Pat. No. 10,189,311

AIRLESS TIRE

SUMITOMO RUBBER INDUSTRIE...

1. An airless tire, comprising:a plurality of tire pieces comprising a first tire piece and a second tire piece such that the first tire piece and the second tire piece are integrated in alignment in a tire axial direction; and
a coupling portion configured to couple one of a first inner periphery portion and a second inner periphery portion to an axle,
wherein the first tire piece comprises a first tread ring, the first inner periphery portion and a plurality of first spokes such that the first tread ring has a cylindrical form and a ground contact surface, the first inner periphery portion is formed on a radial direction inner side of the first tread ring, and the plurality of first spokes is connecting the first tread ring and the first inner periphery portion, the second tire piece comprises a second tread ring, the second inner periphery portion, and a plurality of second spokes such that the second tread ring has a cylindrical form and a ground contact surface, the second inner periphery portion is formed on a radial direction inner side of the second tread ring, and the plurality of second spokes is connecting the second tread ring and the second inner periphery portion, the first inner periphery portion includes a first cylindrical portion formed on a tire radial direction inner side of the plurality of first spokes, and a first flange portion projecting on an inner peripheral side of the first cylindrical portion and configured to be fixed to the coupling portion, and the second inner periphery portion includes a second cylindrical portion formed on a tire radial direction inner side of the plurality of second spokes, and a second flange portion projecting on an inner peripheral side of the second cylindrical portion and configured to be fixed to the coupling portion.

US Pat. No. 10,189,310

AIRLESS TIRE

SUMITOMO RUBBER INDUSTRIE...

1. An airless tire comprising:a tread ring having a cylindrical form and a ground contact surface;
a hub positioned on a radial direction inner side of the tread ring and configured to be fixed to an axle; and
a spoke structure connecting the tread ring and the hub,
wherein the tread ring includes a tread rubber layer, a first reinforcing cord layer, a second reinforcing cord layer and a shear rubber layer such that the tread rubber layer has the ground contact surface, the first reinforcing cord layer is positioned on a radial direction inner side of the tread rubber layer, the second reinforcing cord layer is positioned on a radial direction inner side of the first reinforcing cord layer, and the shear rubber layer is positioned between the first reinforcing cord layer and the second reinforcing cord layer, the first reinforcing cord layer comprises a first array layer comprising a plurality of first reinforcing cords, and a first topping rubber portion covering the first array layer, the second reinforcing cord layer comprises a second array layer comprising a plurality of second reinforcing cords, and a second topping rubber portion covering the second array layer, each of the first topping rubber portion and the second topping rubber portion has an inner topping rubber portion adjacent to the shear rubber layer, and an outer topping rubber portion, and at least one of the first topping rubber portion and the second topping rubber portion has the inner topping rubber portion formed of a rubber composition comprising a rubber component such that the rubber component comprises a butadiene rubber in a content rate in a range of 10 to 100% by mass, an ?,?-unsaturated carboxylic acid metal salt in an amount in a range of 10 to 80 parts by weight with respect to 100 parts by mass of the rubber component, and a peroxide.

US Pat. No. 10,189,309

WHEEL BEARING ASSEMBLY

ILJIN GLOBAL CO., LTD., ...

1. A wheel bearing assembly, comprising:a wheel hub fastened to a vehicle wheel so as to rotate as a unit and having a ring-shaped fastening portion; and
a brake disc having a ring-shaped fastening portion fastened to the fastening portion of the wheel hub,
wherein the fastening portion of the wheel hub protrudes radially outward, the fastening portion of the brake disc protrudes radially inward, and the fastening portion of the wheel hub and the fastening portion of the brake disc are fastened to each other while being axially overlapped,
wherein the wheel hub includes a cylindrical portion and a flange portion formed to extend radially outward from the cylindrical portion and to continuously extend in a circumferential direction, and
wherein the fastening portion of the wheel hub is formed at a radial outer edge of the flange portion so as to protrude radially outward.

US Pat. No. 10,189,307

WHEEL ASSEMBLIES

GEO Plastics, Los Angele...

13. An assembly comprising:a pin sleeve configured to contain a retaining member and a biasing element;
a wheel mounting sleeve including an axle bore configured to receive an axle;
an annular rib extending radially outward from the wheel mounting sleeve at a position longitudinally spaced from the pin sleeve; and
a spacer extending longitudinally from the wheel mounting sleeve, the spacer monolithically formed with the wheel mounting sleeve.

US Pat. No. 10,189,306

REAR HUB AND BICYCLIC AXLE

Canyon Bicycles GmbH, Ko...

1. A rear hub comprising:a hub body rotatably supported on a hub axle,
a sprocket carrier rotatably supported on the hub axle, and
a freewheel mechanism for axially coupling the hub body and the sprocket carrier,
further comprising a decoupling element for decoupling the hub body and the sprocket carrier,
wherein the decoupling element is actuated by a manual actuating element which is connected with an actuating mechanism on a bicycle handlebar.

US Pat. No. 10,189,303

BICYCLE RIM FOR TUBELESS TIRE

HED CYCLING PRODUCTS, INC...

1. A bicycle rim assembly comprising:a bicycle rim comprising:
a center channel that is continuous from a channel first outer sidewall to a channel second outer sidewall, the channel first outer sidewall disposed to a first side of a centerline of the rim and the channel second outer sidewall disposed to a second side of the centerline of the rim, the channel having a channel diameter;
a pair of rim sidewalls disposed at the lateral peripheries of the bicycle rim;
a pair of bead seats disposed proximate to the rim sidewalls and having a bead seat diameter;
an attachable annular strip formed separately from the bicycle rim and attached to the bicycle rim along a center line of the center channel, the attachable annular strip comprising:
a set of strip sidewalls;
a center section extending between the strip sidewalls, wherein the strip sidewalls are spaced at less than a center channel width such that the strip forms a pair of bead channels in cooperation with the channel first outer sidewall and channel second outer sidewall, the bead channels positioned laterally inward of the bead seats, the pair of bead channels having a bead channel diameter that is less than the bead seat diameter, and the center section having a radially outer surface with a diameter that is greater than the bead seat diameter.

US Pat. No. 10,189,297

WALL APPLIQUé

18. A wall appliqué comprising:a body portion consisting of a single layer having a front side and a back side wherein the body portion is a polyurethane material that is not a cross-linked polyethylene foam and sized and shaped to be used as architectural embellishment for a wall wherein the body portion has a thickness that is greater than .033 inches and less than ?? and has a Shore hardness of 10-60 and wherein the body portion is configured to be cut with handheld scissors; and
an adhesive portion comprising an adhesive layer wherein the adhesive portion is directly on the back side of the single-layer body portion wherein the adhesive layer is configured to bond the body portion to a wall by applying pressure to the body portion when the body portion is positioned on a wall wherein the adhesive portion is co-extensive with the back side of the body portion.

US Pat. No. 10,189,296

INSTRUMENT, SUCH AS A WRITING PEN, MAKE-UP PEN, TOOL OR TOY AND METHOD FOR USING SUCH AN INSTRUMENT

1. An instrument, said instrument comprising:a body adapted for being grasped by a user;
at least two modules, each module being independent of the other module(s), including an active portion and being movable relatively to the body; and
for each module, a mechanism for guiding the module in translation and in rotation along the body, the module being movable relatively to the body successively in a translation parallel to a first axis and in a rotation around a second axis which is perpendicular to the first axis and which is secured to the body, between a rest configuration wherein the active portion of the module is housed in the body and a use configuration wherein the active portion of the module protrudes out of the body,wherein both modules or two of the modules are positioned on either side of a same arm of the body, which extends along the first axis from a base of the body as far as one end of the body, the respective active portions of both of these modules being housed in the base in the rest configuration and extending along the first axis beyond the end of the body in the use configuration.

US Pat. No. 10,189,239

ABILITY TO THREE-DIMENSIONALLY PRINT AN APERTURE MASK ON A MULTI SPECTRAL FILTER ARRAY

MATERION CORPORATION, Ma...

7. A three-dimensional inkjet printer, comprising:a tray comprising a vacuum chuck configured to support an associated prefabricated multi-spectral optical filter array; and
a print block, comprising:
at least one inkjet head in fluid communication with a reservoir for storing associated photopolymer resin, the at least one inkjet head configured to deposit the associated photopolymer resin onto a surface of the prefabricated multi-spectral optical filter array forming an aperture mask thereon, and
at least one ultraviolet lamp for illuminating deposited photopolymer resin on the surface of the prefabricated multi-spectral optical filter array, wherein the vacuum chuck is further configured to locate a start position of the at least one inkjet head relative to the prefabricated multi-spectral optical filter array,
wherein the prefabricated multi-spectral optical filter array comprises a plurality of optical filter elements of different optical filter types, the optical filter elements having slanted sidewalls, the optical filter elements bonded together at the slanted sidewalls to form an optical filter array.

US Pat. No. 10,189,197

SOFT AND VELVET TOUCH BARRIER LAMINATE

ESSEL PROPACK LIMITED, M...

1. A soft and velvet touch barrier laminate comprising:(a) a printable layer comprising a polypropylene elastomer;
(b) a core layer adjacent to the printable layer;
(c) a laminating layer adjacent to the core layer;
(d) a barrier layer between first and second bond layers, wherein the first bond layer is between the laminating layer and the barrier layer; and
(e) an inner polyethylene (PE) layer adjacent to the second bond layer which is in contact with the barrier layer;
wherein said polypropylene elastomer has Vicat softening temperature in the range of 60° C. to 90° C., wherein the printable layer further comprises high density polyethylene (HDPE); an anti-block additive; and a colorant.

US Pat. No. 10,189,191

COLLECTION OF PROCESS DATA USING IN-SITU SENSORS

THE BOEING COMPANY, Chic...

1. A system for molding a composite layup inside an autoclave, comprising:a mold tool;
a vacuum bag sealed to the mold tool and having a plurality of openings therein at different sensing locations on the vacuum bag;
a plurality of first MEMS vacuum pressure sensors attached to the vacuum bag and respectively coupled through the openings to an interior of the vacuum bag;
at least one opening in the mold tool;
a second MEMS vacuum pressure sensor mounted within the opening in the mold tool and configured to sense either a vacuum pressure or a fluid pressure inside the at least one opening in the mold tool; and
a processor configured to be placed inside the autoclave and to collect and process pressures sensed by the plurality of first MEMS vacuum pressure sensors and the second MEMS vacuum pressure sensor.

US Pat. No. 10,189,189

MOLDING METHOD AND MOLD THEREFOR

KAGA SANGYO CO., LTD., N...

1. A method of molding a product by rotating a mold, comprising:(i) filling a liquid synthetic resin material into the mold;
(ii) disposing the mold, which has been filled with the liquid synthetic resin material in step (i), in a vacuum interior of a housing of a mixer; and
(iii) driving the mixer to subject the mold in the vacuum interior to a planetary motion, thereby agitating the synthetic resin material while degassing it and generating an agitated/degassed synthetic resin material in the mold and thereby molding the product by rotational molding,
wherein the planetary motion is generated by driving the mixer to cause the mold to orbit about an orbital axis and simultaneously rotate about a rotational axis, wherein the rotation axis is eccentric from the orbital axis and is tilted relative to the orbital axis.

US Pat. No. 10,189,188

NANOIMPRINT LITHOGRAPHY ADHESION LAYER

Canon Kabushiki Kaisha, ...

1. A compound of Formula A-1:
wherein n is an integer and R is C1-10 alkyl.

US Pat. No. 10,189,182

PROCESSING SYSTEM

DISCO Corporation, Toky...

1. A processing system comprising:a processing apparatus having functional units including a holding unit that holds a workpiece by a holding surface, a processing unit that processes the workpiece held by the holding unit, and a feed unit that moves the holding unit and the processing unit relatively;
a detecting unit that is provided for part or all of the functional units and detects any of vibration, current, voltage, load, speed, torque, pressure, temperature, flow rate, change in a taken image, and thickness of the workpiece; and
a data accumulating unit that accumulates information included in a signal output from the detecting unit as accumulated data,
the processing apparatus further comprising,
a determining unit that determines states of the functional units on the basis of the accumulated data in the data accumulating unit, and
a normal data storing unit that stores information included in a signal output from the detecting unit when the functional units are normal based on a predetermined condition as normal data;
the determining unit comparing the accumulated data in the data accumulating unit and the normal data stored in the normal data storing unit and determining the states of the functional units,
wherein the processing apparatus is a cutting apparatus including, as the processing unit, a cutting unit in which a cutting blade that carries out cutting processing of the workpiece held by the holding unit is mounted,
the cutting apparatus includes a vibration detecting unit that detects vibration of the cutting blade as the detecting unit,
information on vibration when cutting processing of the workpiece is carried out by the cutting blade is accumulated in the data accumulating unit as the accumulated data,
information on vibration when cutting processing of the workpiece is carried out by a proper cutting blade corresponding to the workpiece is stored in the normal data storing unit as the normal data, and
the determining unit compares the accumulated data in the data accumulating unit and the normal data stored in the normal data storing unit and determines whether or not cutting processing of the workpiece is normally carried out.

US Pat. No. 10,189,168

SOFT ROBOTIC ACTUATOR ENHANCEMENTS

Soft Robotics, Inc., Bed...

1. An apparatus comprising:one or more soft robotic actuators, the soft robotic actuators comprising: a hollow body including an elastomeric material, the hollow body configured to accept an inflation fluid, a proximal end having an opening for receiving the inflation fluid, and a distal end opposite the proximal end that forms a gripping tip;
a hub comprising an interface for connecting to the one or more soft robotic actuators; and
an angular adjustment device for adjusting an angle of the one or more soft robotic actuators relative to the hub or relative to each other, the angular adjustment device comprising a rotatable component having a first interface configured to attach directly to the proximal end of one of the soft robotic actuators and a second interface configured to rotatably attach the angular adjustment device to the hub, the second interface configured to rotate the attached actuator with respect to the hub to change a relative angle between the attached actuator and the hub.

US Pat. No. 10,189,146

ABRASIVE TOOLS AND METHODS FOR FORMING SAME

SAINT-GOBAIN ABRASIVES, I...

1. An abrasive tool comprising:a bonded abrasive including a body comprising abrasive particles contained within a bond material, wherein the body comprises a second major surface opposite a first major surface, and a peripheral surface extending between the first major surface and the second major surface; and
a barrier layer directly bonded to the first major surface and second major surface of the body, the barrier layer comprising a first polymer including a biaxially-oriented material.

US Pat. No. 10,189,145

ABRASIVE TOOLS AND METHODS FOR FORMING SAME

SAINT-GOBAIN ABRASIVES, I...

1. An abrasive tool comprising:a bonded abrasive including a body comprising abrasive particles contained within a bond material; and
a barrier layer bonded to at least a major surface of the body, the barrier layer comprising a polymer including a biaxially-oriented material.

US Pat. No. 10,189,133

MEASUREMENT, CALIBRATION AND COMPENSATION SYSTEM AND METHOD FOR MACHINE TOOL

NATIONAL CHUNG SHAN INSTI...

1. A measurement, calibration and compensation system for a machine tool, comprising:a first positioning base having a first XY plane and a first XZ plane, wherein the first positioning base is for mounting on a machine bed of the machine tool and located at a lateral side of an x-axis linear translation stage of the machine tool, the x-axis linear translation stage is mounted on the machine bed, and the first positioning base is made of a material selected from a group consisting of a zero-expansion glass material, an Invar material, and a granite material;
two first speckle image sensors for mounting on an object holding unit of the machine tool, wherein the object holding unit is translatable on the x-axis linear translation stage along the x-axis, the first speckle image sensors separately sense along the x-axis a speckle position of the object holding unit at the first XY plane and a speckle position of the object holding unit at the first XZ plane before and after the machine tool is started, and a difference between the speckle positions of the object holding unit at the first XY plane before and after the machine tool is started and a difference between the speckle positions of the object holding unit at the first XZ plane before and after the machine tool is started are used for calibrating and compensating a position of the object holding unit by an axis control system when the machine tool is machining;
a second positioning base having a second XY plane and a second YZ plane, wherein the second positioning base is provided for mounting on the machine bed of the machine tool and located at a lateral side of a y-axis linear translation stage and a z-axis linear translation stage of the machine tool, the y-axis linear translation stage is mounted on the machine bed, and the z-axis linear translation stage is translatable on the y-axis linear translation stage along the y-axis and the second positioning base is made of a material selected from the group consisting of a zero-expansion glass material, an Invar material, and a granite material; and
two second speckle image sensors, separately mounting on a cutter holding unit and the z-axis linear translation stage of the machine tool, wherein the cutter holding unit is translatable on the z-axis linear translation stage along the z-axis, one of the two second speckle image sensors senses a speckle position of the cutter holding unit along the y-axis at the second XY plane before and after the machine tool is started for machining, the other second speckle image sensor senses a speckle position of the cutter holding unit along the Z axis at the second YZ plane before and after the machine tool is started, and a difference between the speckle positions of the cutter holding unit at the second XY plane before and after the machine tool is started and a difference between the speckle positions of the cutter holding unit at the second YZ plane before and after the machine tool is started are used calibrating and compensating a position of the cutter holding unit by the axis control system when the machine tool is machining.

US Pat. No. 10,189,132

CORE GRASPING APPARATUS

TOYOTA JIDOSHA KABUSHIKI ...

12. A core grasping apparatus that grasps a core including a core main body and a core print provided at one end of the core main body, the core grasping apparatus comprising:a first holding device including an inflatable and deflatable first holding part, the first holding device being configured to hold the core print by inflating the first holding part so as to bring the first holding part into contact with the core print;
a second holding device including an inflatable and deflatable second holding part, the second holding device being configured to hold the core print by inflating the second holding part so as to bring the second holding part into contact with the core print; and
a turning suppression part configured to suppress the core from turning upon the core print being held by the first holding device and the second holding device, the turning suppression part applying, to the core print, a force that suppresses a turning moment acting on the core around a straight line connecting portions of the core print at which the first holding part and the second holding part respectively come in contact with the core print, wherein
a third holding device including an inflatable and deflatable third holding part is used as the turning suppression part, and
the third holding part applies the force that suppresses the turning moment acting on the core to the core print by coming in contact with the core print at a position separated from the straight line connecting portions of the core print at which the first holding part and the second holding part respectively come in contact with the core print.

US Pat. No. 10,189,121

ORGANIC ACID-OR LATENT ORGANIC ACID-FUNCTIONALIZED POLYMER-COATED METAL POWDERS FOR SOLDER PASTES

1. Solder particles having a polyalkylene polymer with latent organic acid functional groups coated on at least a portion of the surface thereof, wherein the solder particles are made from an alloy selected from the group consisting of tin/silver/copper, tin/zinc, tin/bismuth, tin/lead, and tin/indium/bismuth and wherein the solder particles have a varied size distribution of diameters of about 0.5 to about 100 um, wherein the polyalkylene is selected from the group consisting of polyethylene, polypropylene, polybutylene and mixtures thereof and wherein the latent organic acid functional group is an anhydride.

US Pat. No. 10,189,110

PLASMA CUTTING METHOD AND PLASMA CUTTING DEVICE

KOMATSU INDUSTRIES CORPOR...

6. A plasma cutting device configured to cut out a plurality of cutout members from a plate blank, comprising:a mount table onto which the plate blank to be cut is mounted;
a plasma torch configured to generate a plasma arc and movable relative t the F fount table in, a horizontal direction and in an up-and-down direction; and
a controller programmed to control movement of the plasma torch relative to the mount table and generation of the plasma arc from the plasma torch, wherein
the controller is programmed to
receive a set data regarding a processing line;
form an aperture on an outer peripheral side of a given one of the cutout members by maintaining the plasma torch at a first height from the plate blank on the outer peripheral side or the given cutout member while the plasma arc is, being generated from the plasma torch and by moving the plasma torch relative to the plate blank by a predetermined distance in the horizontal direction; and
form a continuous cutting groove along an outer contour of the given cutout member by setting the plasma torch at a second height lower than the first height and by moving the plasma torch in the horizontal direction along an incision part and the processing line continuing to the incision part,
the controller being further programmed to set the plasma torch at a position lower than the first height when the plasma arc begins to be generated, and to then move the plasma torch in the horizontal direction and simultaneously in an upward direction to the first height.

US Pat. No. 10,189,096

CRANKSHAFT MACHINING SYSTEM AND CRANKSHAFT MACHINING METHOD

KOMATSU NTC LTD., Toyama...

1. A crankshaft machining system comprising:a center hole boring device configured to bore a center hole in each of both end surfaces of a crankshaft blank to obtain a post-centering crankshaft blank having a pair of center holes;
a post-centering balance meter configured to measure a shape of the post-centering crankshaft blank with reference to the pair of center holes;
a controller configured and arranged to control the post-centering balance meter; and
a cutting device configured to cut a main journal and a pin journal of the post-centering crankshaft blank after the shape of the post-centering crankshaft blank has been measured,
the controller being configured to control the post-centering balance meter to determine a principal axis of inertia on the basis of the measured shape of the post-centering crankshaft blank, the controller further being configured to transmit information indicating intersections between the principal axis of inertia and both end surfaces of the post-centering crankshaft blank to the center hole boring device prior to cutting of the main journal and the pin journal of the post-centering crankshaft blank, and
the center hole boring device configured to bore a center hole in each of both end surfaces of another crankshaft blank to be loaded next on the basis of the information indicating the intersections.

US Pat. No. 10,189,094

MULTIFUNCTIONAL ADJUSTABLE DRILLING MACHINE

CITIC DICASTAL CO., LTD.,...

1. A multifunctional adjustable drilling machine, comprising supporting leg seats, a frame, a bottom plate, driller supports, driller support index plates, drillers, a compression cylinder bracket, a compression cylinder support, a compression plate, a compression cylinder, motors, belt pulleys, conveying belts, a clamp body and a drill bit guide sleeve assembly, whereinthe supporting leg seats are connected with the frame, the frame being connected with the bottom plate, the bottom plate being connected with the driller supports, the bottom plate being provided with holes and positioning pins matched with the driller supports, angles of the driller support index plates being adjustable, the drillers machine holes in an automobile die casting at different angles, and the compression cylinder bracket and the compression cylinder support being connected to the bottom plate; the compression plate being connected to a piston rod of the compression cylinder, the compression cylinder being arranged on the compression cylinder support, the motors driving the belt pulleys and the conveying belts to rotate, the automobile die casting being positioned by the clamp body, and the compression plate clamping the automobile die casting via the compression cylinder; and the drill bit guide sleeve assembly exerting an effect of preventing the drillers from deviating.

US Pat. No. 10,189,074

RING ROLLING PROCESS AND APPARATUS FOR RING ROLLING

Cambridge Enterprise Limi...

1. A ring rolling process comprising:providing a ring shaped workpiece, the ring shaped workpiece having a principal axis, an inner radial surface, an outer radial surface, a first axial surface and a second axial surface;
subjecting the workpiece to radial pressure between a forming roll acting on the outer radial surface and a mandrel roll acting on the inner radial surface, at a radial roll bite region, wherein:
a first axial roll and a second axial roll are provided at the first axial surface and the second axial surface respectively, to subject the workpiece to axial pressure, the first and second axial rolls being provided at an angular position, measured around the workpiece and with respect to the principal axis, within ±10° of said radial roll bite region;
and, in order to control the cross sectional shape of the workpiece at least one of the following conditions (i) and (ii) applies:
(i) the mandrel roll has a projecting portion for contact with the workpiece, the projecting portion having an axial extent which is smaller than the axial height of the workpiece, the mandrel roll being axially moveable relative to the workpiece during the ring rolling process so that the projecting portion is applied to different axial locations of the workpiece, in order to control the shape applied to the workpiece;
and
(ii) the forming roll has a projecting portion for contact with the workpiece, the projecting portion having an axial extent which is smaller than the axial height of the workpiece, the forming roll being axially moveable relative to the workpiece during the ring rolling process so that the projecting portion is applied to different axial locations of the workpiece, in order to control the shape applied to the workpiece;
and wherein the first and second axial rolls are independently moved to adapt to the changing cross section of the workpiece during forming.

US Pat. No. 10,189,067

TOOL HOLDERS USABLE WITH TOOLING HAVING DIFFERENT TANG STYLES AND/OR CONFIGURED WITH MECHANICALLY-ACTUATED CLAMP ASSEMBLY

Wilson Tool International...

1. A tool holder configured for use with tools having different tang styles, the tool holder comprising:a housing;
a mechanism that is mechanically actuatable, the mechanism accessible through an opening defined in the housing; and
a clamp assembly operably coupled to the mechanism and comprising:
a clamp plate; and
one or more clamping fingers;
wherein the clamp plate is defined as a longitudinal body that has an extent spanning across the one or more clamping fingers, the longitudinal body of the clamp plate having an end contacting the one or more clamping fingers, the one or more clamping fingers movable in order to secure tools having different tang styles between the fingers and a stationary wall of the housing, movement of the one or more clamping fingers corresponding to movement of the clamp plate body end which stems from adjustment of the mechanism; and
wherein the clamp plate has at least two differing tolerance areas provided therein to enable different degrees of freedom or play for the clamp plate body end both in direction of corresponding movement of the end and in crosswise direction when securing a tool via the clamp assembly, a first tolerance area comprising a plurality of first slits each defined across the extent of the clamp plate body end and thereby forming a plurality of clamp plate portions in contact with the one or more clamping fingers, a second tolerance area defined across a depth of each of the clamp plate portions.

US Pat. No. 10,189,064

CONTROL SYSTEM AND METHOD FOR TAPERED STRUCTURE CONSTRUCTION

Keystone Tower Systems, I...

1. A system for forming a tapered structure, the system comprising:at least three rolls including at least one bend roll and at least two guide rolls, the at least two guide rolls including rollette banks comprising a plurality of rollettes;
a rollette steering mechanism controllable to steer the plurality of rollettes to change an angle of the plurality of rollettes with respect to a stock material to change a first position of the stock material as the stock material is fed into the at least three rolls;
an infeed actuator controllable to adjust a second position of the stock material as the stock material is fed into the at least three rolls, the stock material forming the tapered structure as the stock material is rolled through the at least three rolls; and
a joining element configured to join edges of the stock material together as the stock material is rolled through the at least three rolls to form the tapered structure;
a model implemented on a computer, the model comprising a sequence of positions and infeed angles of the stock material as the stock material is fed into or through the at least three rolls for forming the tapered structure;
a sensor configured to detect a position of the stock material; and
a controller configured to receive instructions based on the sequence of positions and infeed angles of the model and to receive feedback from the sensor, the controller further configured to selectively send a first control signal to the rollette steering mechanism to steer the plurality of rollettes for changing the first position of the stock material and to selectively send a second control signal to the infeed actuator to adjust the second position of the stock material, wherein each one of the first control signal and the second control signal is based on a combination of the instructions based on the sequence of positions and infeed angles of the model and the feedback from the sensor.

US Pat. No. 10,189,059

DEVICES FOR CROSS BORE SAFEGUARD DURING SEWER SYSTEM CLEANOUTS

Gas Technology Institute,...

1. A sewer system cleanout safety device for cross bore safeguard during sewer system cleanout, said safety device comprising:a housing for placement at a sewer cleanout opening to prevent passage of gas out through the sewer cleanout opening during the sewer system cleanout,
the housing having opposed inner and outer cleanout opening surfaces, and a peripheral surface extending between said inner and outer cleanout opening surfaces, and
the housing having a cavity extending between said inner and outer cleanout opening surfaces to permit passage of a sewer system cleanout implement therethrough, the housing having a cavity lining surface to seal with the sewer system cleanout implement passing therethrough.

US Pat. No. 10,189,055

COLOR BASED OPTICAL GRADING SYSTEM WITH MULTI REFLECTANCE AND MULTI-ANGLE VIEWS

NANOPIX INTEGRATED SOFTWA...

1. A novel color based optical grading system with multi-reflectance and multi-angle views for grading objects of different external characteristics, said optical grading system comprising of multiple advanced optics units which are placed above and below a flat transparent conveyor which is an arrangement of multiple trays forming multiple trays, where each tray is an assembly of multiple flat transparent surfaces with facility for multi-vision of single object in a single flat transparent surface in a pre-defined position; and at least one master controller; wherein the arrangement of said multiple advanced optics units above and below the conveyor is always kept in a way so as to provide exactly two advanced optics units for covering both top and bottom sides of each object to be graded; and wherein each advanced optics unit comprises of:multiple programmable cameras which are placed at a specific distance from said flat transparent surface and said multiple cameras are adapted to capture different views of each object at different frequencies of electromagnetic spectrum and to get a proper focus of said flat transparent surface;
multiple mirrors/multiple prisms to get redirected light reflected from side views of each object to said cameras which enable said multiple cameras to capture multi-reflectance and multi-angle based views of said object to analyze said object and said multiple mirrors/prisms also enables said cameras to get a proper focus of reflections of said multiple mirrors/prisms and said object;
at least one mirror/prism adjustment assembly to adjust the angles of said multiple mirrors or multiple prisms relative to the position of said object on said flat transparent surface; to adjust said mirrors/prisms according to size variations of multiple objects; and to vary vertical or horizontal distance of said mirrors/prisms from said flat transparent surface;
multiple spectral light sources to illuminate every side view of said object at different frequencies of electromagnetic spectrum, wherein said spectral light sources are correlated with all said cameras and said light sources is either flash lighting or continuous lighting, and some of said light sources are triggered with some respective cameras while others light sources are turned off as per the requirement;
at least one backlighting dome placed exactly opposite of each advanced optics unit, wherein said each backlighting dome is arranged in said optical grading system in such a way that there lays at least one flat transparent surface between each said backlighting dome and each advanced optics units to provide uniform backlight for capturing objects in multi-reflection and multi-angle based views and said backlighting dome comprises of multi-colored, flashing or non-flashing back lights, wherein said backlighting dome is optionally covered with a diffusion sheet which is adapted to change in color of said sheet according to different characteristics of said object; and
at least one image processing unit for processing multi-reflectance and multi-angle based views of said object taken by said cameras; wherein said multiple cameras said multiple spectral light sources, said multiple adjustable mirrors/multiple adjustable prisms, said mirror adjustment assembly, said backlighting dome and said image processing unit work collaboratively to ensure the enhanced surface analysis of said object, and further wherein said advanced optics unit enhances the sideways features of said objects including sideways lighting from different sides using multiple reflections from multiple angles by enabling said multiple cameras to analyze said object from all side views and also from top and bottom views for accurate complete analysis of said object; wherein said master controller of said optical grading system intelligently remembers the position of each said object dropped on each flat transparent surface of each tray and decide the final grade of each said object based on inputs received from each image processing unit of corresponding each advanced optics unit by comparing said inputs with pre-determined data.

US Pat. No. 10,189,025

CAM ASSEMBLY COMPRISING CYLINDRICAL HOUSING

XG SCIENCES, INC., Lansi...

1. A cam assembly comprising:a solid cylinder having a near end and a distal end and an opening extending from the near end through the distal end;
wherein the opening includes an inset;
wherein the near end is configured at a slight angle from the vertical, the angle comprising less than about 15°;
wherein the opening extending from said near end through said distal end is angled through the cam assembly, the opening beginning at the near end and near a bottom edge of the solid cylinder and terminating through the distal end near a top edge of the solid cylinder.

US Pat. No. 10,189,024

GYRATORY CRUSHER FRAME

SANDVIK INTELLECTUAL PROP...

1. A gyratory crusher frame part comprising:a topshell mountable upon a bottom shell, the topshell having an annular wall extending around a longitudinal axis of the frame part, the topshell including an outward facing surface and an inward facing surface relative to the longitudinal axis, the annular wall being defined between the outward and inward facing surfaces;
a spider having a plurality of arms formed integrally with the topshell and extending radially outward from a cap positioned at the longitudinal axis, each arm of the plurality of arms having a first portion extending in a radially outward direction from the cap and a second portion extending in an axial direction from an outer region of the first portion; and
an annular flange positioned between the second portion of each arm and the annular wall, the flange having an outer circumferential perimeter and an inner circumferential perimeter relative to the longitudinal axis, wherein a radially outermost region of the second portion of each arm is positioned radially inward of the outer circumferential perimeter of the flange, the annular wall including a concave section at the outer surface, the concave section having an upper first half and a lower second half along the axial direction, the upper first half of the concave section being positioned immediately below the annular flange and extending from a lower surface of the flange, wherein the upper first half of the concave section is a substantially uniform curve extending continuously in the circumferential direction and completely around the longitudinal axis, the upper first half of the concave section in the axial direction closest to the flange being devoid of any axially extending shoulders that would otherwise interrupt the continuous circumferential curve and a majority of the lower second half of the concave section in the axial direction including a curvature profile substantially equal to a curvature profile of the upper first half in the axial direction, and the second portion of each arm including a pair of wings that taper outwardly in the axial direction from the first portion to the annular flange, each wing of the pair of wings extending substantially in the circumferential direction with the flange.

US Pat. No. 10,189,021

MICROFLUIDIC CHIP, MANUFACTURING METHOD THEREFOR AND ANALYSIS DEVICE USING SAME

NANOBIOSYS INC., Seoul (...

1. A microfluidic chip comprising:a substrate comprising, an inflow part penetrating the substrate in a thickness direction,
an outflow part penetrating the substrate in the thickness direction, and
a fluid channel defined to connect the inflow part and the outflow part and extending in a first direction within the substrate, wherein the thickness direction and the first direction are different from one another; and
a film attached to the substrate and covering at least a portion of at least one of the inflow part, the outflow part, and the fluid channel, the film configured to protect at least one of the inflow part, the outflow part and the fluid channel from the outside;
wherein the film includes a first film attached to a top surface of the substrate and a second film attached to a bottom surface of the substrate;
wherein the fluid channel includes an upper fluid channel formed on a top surface of the substrate; a lower fluid channel formed on a bottom surface of the substrate; and a third fluid channel connecting the upper fluid channel and the lower fluid channel,
wherein a thickness of the at least one film is smaller than a thickness of the substrate.

US Pat. No. 10,189,020

SPECIMEN COLLECTION APPARATUS

Alpha Tec Systems, Inc., ...

1. A sample collection apparatus, comprising:a container having an interior portion configured to contain a sample and an opening to the interior portion, the opening for receiving the sample;
a funnel configured to be secured to the opening of the container, the funnel having a mouth portion and a neck portion depending from the mouth, the neck portion configured to be inserted into the opening of the container; and
a closure assembly including:
a first closure structure configured to releasably seal the opening of the container, the first closure structure including a chamber that is in fluid communication with the interior portion of the container when the opening is sealed by the first closure structure,
a chemical reagent contained within the chamber, and
a second closure structure configured to releasably cover the mouth portion of the funnel, wherein the first closure structure is removably attached to the second closure structure.

US Pat. No. 10,189,017

HONEYCOMB MONOLITH STRUCTURE

YARA INTERNATIONAL ASA, ...

1. A honeycomb monolith structure, comprising:a plurality of cell walls defining a plurality of polygonal channels, the plurality of cell walls and channels extending in parallel along a common direction from an entrance end to an outlet end of the structure in a fluid flow direction and where the channels are open in both ends, wherein a transversal cross section of a polygonal channel has a convex polygon shape, wherein at least 50% of the internal angles between two adjacent walls of the convex polygon are greater than 90 degrees and wherein a cell diameter ratio LL/LS (longest over shortest diameter) is greater than 1.5 and wherein a majority of the channels have the same flow resistance.

US Pat. No. 10,189,002

APPARATUS FOR FLOW-THROUGH OF ELECTRIC ARCS

Magnegas Corporation, Cl...

1. A system for the production of a gas from a fluid, the system comprising:an anode connected to a first polarity of power;
a cathode connected to a second, opposing polarity of power, the cathode separated from the anode by a gap, whereby a voltage differential between the anode and the cathode forms an arc there between;
a sleeve having a bore, the bore surrounding at least the gap between the anode and the cathode, the sleeve comprising of an electrical insulator, the bore forming a venturi that has a wider cross-sectional area at each end of the bore and a narrower cross-sectional area at a location of the gap;
an input port fluidly interfaced to a first end of the bore;
an output port fluidly interfaced to a second end of the bore;
means for flowing the fluid from the input port, through the bore of the sleeve, and out of the output port such that the fluid flows from an area around the anode to an area around the cathode or from the area around the cathode to the area around the anode; and
a vessel body made of a metallic material covering an outer surface of the sleeve;
whereas, at least some of the bi-products that are released from the fluid by the reaction are prevented from accumulating on either the anode or the cathode.

US Pat. No. 10,188,979

FILTER WITH OPTIMIZED FLUID FLOWS

Norgren Limited, Staffor...

1. A filter (100) with optimized fluid flows to remove one or more components from a fluid, comprising:a filtering media tube (102) adapted to remove the one or more components from the fluid; and
an inlet cap (104) coupled to the filtering media tube (102), the inlet cap (104) adapted to receive the fluid flow that is substantially transversal to a major axis X of the filter (100), wherein the inlet cap (104) further comprises an inlet baffle (304) adapted to uniformly distribute the fluid to the filtering media tube (102), wherein the inlet baffle comprises a baffle base (402) and a plurality of fins (404, 406, 408).

US Pat. No. 10,188,962

GRID-BASED VIRTUAL REALITY ATTRACTION SYSTEM

Unchartedvr Inc., San Ra...

1. A grid-based virtual reality (VR) attraction system, comprising:a grid aligned stage kit that corresponds to a plurality of stage plans associated with plurality of VR representations, said grid aligned stage kit comprising:
fixed accessories;
moveable accessories;
a stage comprising a platform having a pattern of markings along at least two dimensions, wherein said stage is configured with accessory mounts arranged on said platform, for affixing said fixed stage accessories to said platform, and wherein said pattern identifies coordinates corresponding to a location of said accessory mounts; and
a plurality of stage sections that are configured to be interconnected according to said pattern to form said platform, wherein said platform is configurable according to said plurality of stage plans comprising at least A×B and C×D, wherein A, B, C, and D are different from each other;
a motion tracking system, configured to track identity, location, and/or orientation of a VR participant on said stage; and
a VR simulation engine, coupled to said motion tracking system, configured to receive said identity, location, and/or orientation, and configured to generate said plurality of VR representations to simulate a virtual environment with virtually represented objects whose locations and orientations correspond to locations and orientations said fixed and moveable accessories that are arranged according to a corresponding stage plan.

US Pat. No. 10,188,957

TOY WITH PROXIMITY-BASED INTERACTIVE FEATURES

Mattel, Inc., El Segundo...

1. A toy comprising: a photosensor;a memory comprising at least one mapping of a plurality of sequential ranges of input states to a plurality of discrete output states;
at least one input signal pathway operably connected to the photosensor;
a microprocessor operably connected to the photosensor through a plurality of input signal pathways, the microprocessor operable to:
select one of the input signal pathways as an active signal pathway,
receive an input signal from the photosensor through only the active signal pathway,
determine that the input signal falls within one of the ranges of input states,
use the at least one mapping to correlate the input state range in which the input signal falls with a selected one of the plurality of discrete output states; and
produce an output signal corresponding to the selected output state; and an output mechanism configured to receive the output signal from the microprocessor and to generate an output corresponding to the selected output state; wherein the memory, the at least one input signal pathway, and the microprocessor are all within the toy.

US Pat. No. 10,188,952

METHOD FOR DYNAMICALLY MAPPING SERVERS

Controlled Protocols, Inc...

1. A non-transitory computer readable medium including a program of instructions for dynamically mapping a plurality of servers that when executed by a computer performs the steps of:defining a three dimensional area of a virtual space divided into independently storable blocks with an integral coordinate system by providing coordinate addresses that have an X, Y and Z component, wherein each component includes a summary address portion and an internal address portion;
mapping coordinate addresses that represent a position within the virtual space to server coordinates, wherein the coordinate address includes an embedded and freely assignable server address so that each block can be transferred and independently stored on one or more of the plurality of servers;
adding a block to any one of the plurality of servers to expand beyond the defined three dimensional area; and
dynamically re-mapping the coordinate address to reflect the new server coordinates of the added block.

US Pat. No. 10,188,915

GOLF CLUB HEAD

TAYLOR MADE GOLF COMPANY,...

1. A golf club head, comprising:a body, defining an interior cavity and comprising:
a sole portion, positioned at a bottom region of the golf club head;
a crown portion, positioned at a top region of the golf club head;
a skirt portion, positioned around a periphery of the golf club head between the sole portion and the crown portion;
a forward region;
a rearward region, opposite the forward region;
a heel region; and
a toe region, opposite the heel region; and
a face portion, coupled to the body at the forward region of the body and comprising a strike plate; and
at least one stiffener comprising a discrete mass of polymeric material within the interior cavity and directly coupled to the face portion at a location with an x-axis coordinate, of a club head origin coordinate system of the golf club head, greater than 20 mm and less than 50 mm or greater than ?50 mm and less than ?20 mm, wherein the polymeric material of the at least one discrete mass has a hardness equal to or greater than about Shore 10D;
wherein:
the golf club head further comprises a retaining wall, coupled to the sole portion, protruding uprightly from the sole portion, and extending lengthwise in a heel-to-toe direction;
the discrete mass of polymeric material is coupled to the retaining wall and interposed between the retaining wall and the face portion;
the golf club head further comprises a slot, formed in the sole portion and extending lengthwise from the heel region to the toe region; and
the retaining wall forms part of the slot.

US Pat. No. 10,188,914

GOLF CLUB HEAD

Bridgestone Sports Co., L...

1. A golf club head comprising a crown portion and a face portion, wherein the crown portion includes a first protruding portion arranged on a side of the face portion and extending from an upper end of the face portion to a back side, a second protruding portion arranged on the back side to be adjacent to the first protruding portion, and a valley portion formed where the first and second protruding portions are connected to one another, the second protruding portion has a convex-curved outer surface extending from the valley portion to a back side end of the crown portion, a width of the first protruding portion in a face-back direction on a plane passing through a face center of the face portion and extending in a vertical direction is smaller than a width of the second protruding portion in the face-back direction, and a protruding height of the second protruding portion is larger than a protruding height of the first protruding portion, wherein curved outer surfaces of the first and second protruding portions abut to form an inflection at the valley portion.

US Pat. No. 10,188,893

HANDHELD WEIGHTED EXERCISING APPARATUS

Mitz Fitness Limited, Ch...

1. An exercise apparatus comprising:a housing configured to receive a hand of a user and extend, in use, up to a wrist area of the user, the housing comprising an upper surface, a lower surface and sides between the upper surface and the lower surface, wherein the housing incorporates a plurality of vents, the plurality of vents located on the upper and the lower surfaces of the housing;
an opening within the housing for receiving the hand of the user;
a handle inside the housing, wherein the handle is disposed within the housing closer to an end of the housing which opposes the opening than to the opening; and
at least one weight provided by, configured within or disposed in relation to the housing and/or the handle,
wherein at least 30% of the area of the upper and the lower surfaces of the housing is the plurality of vents,
whereby in use, the user grips the handle with the hand inside the housing, to lift the at least one weight to perform exercises with the exercise apparatus.

US Pat. No. 10,188,885

HIGH NITROGEN AND OTHER INERT GAS ANTI-CORROSION PROTECTION IN WET PIPE FIRE PROTECTION SYSTEM

Engineered Corrosion Solu...

1. A method of operating a wet pipe fire protection sprinkler system having a pipe network, a source of water for the pipe network, at least one sprinkler head connected with the pipe network, a venting assembly configured to vent gas and not water from said pipe network, and a nitrogen source connected with the pipe network, the method comprising:supplying nitrogen gas from the nitrogen source to the pipe network to increase a pressure in the pipe network above atmospheric pressure;
supplying water to the pipe network, thereby filling the pipe network with water and compressing nitrogen gas in the pipe network; and
discharging gas including nitrogen gas from the pipe network via the venting assembly while supplying water to the pipe network.

US Pat. No. 10,188,869

HARDWARE/SOFTWARE INTEGRATED DESIGN FOR A 3D TREMOR DETECTOR USING TMS IN PARKINSON'S DISEASE AND RELATED DISORDERS

The Florida International...

1. A system comprising:a Transcranial Magnetic Stimulation (TMS) machine;
a Transcranial Stimulation Biofeedback (TSB) Detector device;
a software component comprising instructions stored on one or more non-transitory computer readable media that, when executed by a computing device, direct the computing device to:
receive waveforms from the TSB Detector device;
compute a determination factor based on the waveforms; and
when the determination factor is outside a predetermined range, send an abort signal such that the TMS machine ceases providing magnetic stimulation, and when the determination factor is not outside the predetermined range, allow the TMS machine to continue providing magnetic stimulation,
the TSB Detector device comprising:
a three-axis accelerometer sensor configured to provide three-dimensional signals;
a three-channel analog amplifier configured to receive the three-dimensional signals; and
a capacitor and a resistor connected between the three-axis accelerometer and the three-channel analog amplifier and configured to generate a cut-off frequency, and
three-dimensional tremor signals detected by the TSB Detector device being synchronized with the TMS machine via a dual communication link.

US Pat. No. 10,188,857

LEAD IDENTIFICATION SYSTEM

Nuvectra Corporation, Pl...

1. A method, comprising:inserting an epidural needle into a patient, the epidural needle having a stylet;
removing the stylet from the epidural needle;
inserting an implantable lead through the epidural needle, the implantable lead having a plurality of contacts;
positioning the implantable lead; and
attaching a removable lead indicator to the epidural needle.

US Pat. No. 10,188,856

IMPLANTABLE DEVICE FOR PROVIDING ELECTRICAL STIMULATION OF CERVICAL VAGUS NERVES FOR TREATMENT OF CHRONIC CARDIAC DYSFUNCTION

Cyberonics, Inc., Housto...

1. A vagus nerve neurostimulator for treating chronic cardiac dysfunction, comprising:an implantable neurostimulator comprising:
a pair of helical electrodes;
a nerve stimulation therapy lead electrically coupled to the pair of helical electrodes;
a pulse generator configured to deliver electrical therapeutic stimulation comprising a stimulation waveform applied to both of the helical electrodes via the nerve stimulation therapy lead, the stimulation waveform comprising a form that causes propagation of action potentials in both an afferent direction and an efferent direction within neuronal fibers of a cervical vagus nerve; and
a recordable memory within which is stored stimulation parameters configured to define a periodic duty cycle comprising a percentage of time that the pulse generator delivers the electrical therapeutic stimulation,
wherein the periodic duty cycle is between a lower predefined percentage and an upper predefined percentage,
wherein the pulse generator is further configured to operate under the stimulation parameters stored in the recordable memory.

US Pat. No. 10,188,854

MICROELECTRODE AND MULTIPLE MICROELECTRODES

NEURONANO AB, (SE)

1. An array of medical microelectrodes comprising at least two medical microelectrodes, each medical microelectrode of the at least two medical microelectrodes is configured for insertion into soft tissue, each medical microelectrode comprising:an electrically conducting elongate electrode body including a first proximal end, and a second distal end, the electrode body comprising:
a tip section extending from the distal end;
a main body section extending in a proximal direction from the tip section,
wherein the tip section and the main body section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid;
a dissolution retarding layer on the first electrode matrix element; and
a second electrode matrix section element, different from the first electrode matrix section element, the second electrode matrix section element positioned such that the first electrode matrix section element is positioned between the second electrode matrix section element and the electrode main body,
wherein at least one the first electrode matrix element and the second electrode matrix element comprises a drug configured to be released upon dissolution or biodegradation of the first electrode matrix element, and
wherein the at least two microelectrodes are positioned interspaced on a face of a solid support.

US Pat. No. 10,188,848

NEEDLELESS VALVE INFECTION PREVENTION AND PRE-OPENING DEVICE

CareFusion 303, Inc., Sa...

1. A device for use with a female needleless connector, the device comprising:a housing comprising:
a chamber having a proximal wall;
a side-wall extending from the proximal wall toward a distal opening configured to fit over a proximal end of the female needleless connector; and
an elongate finger extending within the chamber from the proximal wall toward the distal opening,
wherein an outer surface of the elongate finger comprises an undercut that extends from the proximal wall toward the distal end of the elongate finger, and
wherein the side-wall extends beyond a distal end of the elongate finger such that the elongate finger extends into and opens a fluid path through the female needleless connector when the distal opening is distally advanced over the female needleless connector.

US Pat. No. 10,188,834

ADJUSTABLE BENT SHEATH TUBE

Lifetech Scientific (Shen...

1. An adjustable bend sheath tube, comprising a tube body having a distal end and a proximal end, a traction mechanism and a fixing and connecting mechanism; the traction mechanism comprising an anchor ring and a traction wire: the anchor ring being coaxially embedded in a distal elastic segment of the tube body; the traction wire being arranged in a side wall of the tube body, and extending along the axial direction of the tube body; the traction wire comprising a first segment and a second segment which are axially parallel with each other, the first and second segments having a distal end that are connected to each other by a bending portion, with the first segment connected to the fixing and connecting mechanism near the proximal end of the tube body, and with the bending portion extending around the anchor ring to hook the anchor ring, wherein the tube body is provided with first and second independent traction wire channels which are parallel to each other and extend along the axial direction of the tube body, each traction wire channel having a lumen defined by a luminal wall, with the first segment of the traction wire extending inside the first traction wire channel and the second segment of the traction wire extending inside the second traction wire channel, wherein the first and second segments are separated by the luminal walls of the first and second traction wire channels;wherein the first and second traction wire channels are positioned side-by-side from the proximal end of the tube body to the distal end of the tube body along a same side of the tube body.

US Pat. No. 10,188,824

AEROSTASIS IN PULMONARY SURGERY

THE ARIZONA BOARD OF REGE...

1. A method for preventing air leaks from a serosal tissue wound, comprising:providing a device comprising a dispensing apparatus and a delivery apparatus in fluid communication with said dispensing apparatus;
rapidly warming frozen aliquots of fibrinogen and thrombin from about 0° C. to about 37° C. in about 3 minutes or less;
after fibrinogen aliquots and thrombin aliquots are rapidly warmed to about 37° C., the fibrinogen and thrombin aliquots are provided within about 5 minutes from said dispensing apparatus to said delivery apparatus;
mixing a fibrinogen stream and a thrombin stream in a pressurized gas stream, said pressurized gas stream having a pressure of 50 psi or greater;
generating a fibrin-forming foam; and
directing said fibrin-forming foam onto said serosal tissue wound.

US Pat. No. 10,188,822

GAS DELIVERY DEVICE AND SYSTEM FOR USE IN MAGNETIC RESONANCE IMAGING

Mallinckrodt Hospital Pro...

1. A nitric oxide delivery system for providing inhaled nitric oxide (iNO) to a patient situated in an MRI suite, the nitric oxide delivery system comprising:a patient connector;
a source of nitric oxide gas;
a length of an iNO delivery tube;
a source of breathing gas;
a monitoring control circuit;
a delivery control circuit;
a signal processor including a corrective signal processing algorithm comprising determining an inverse of the distortion transfer function produced by the length of iNO delivery tube; determining a ventilator flow profile of individual breaths performed on a continuing basis during ventilation; convolving the inverse of a distortion transfer function with a predicted breath flow profile; and verifying a consistent ventilator flow profile; and
an injector module fluidly connected to the source of nitric oxide, the source of breathing gas and the delivery control circuit; said injector module being located outside an iso-gauss safety line.

US Pat. No. 10,188,816

SYSTEM FOR REMOVING INFECTIOUS SECRETIONS

Flosure Technologies LLC,...

1. A method of decreasing a probability of Ventilator Associated Pneumonia, said method comprising the steps of:a. inserting a tracheal/endotracheal device into the trachea of a patient;
b. inflating a balloon that surrounds a segment of said tracheal/endotracheal device,
whereby a segment of said tracheal/endotracheal device is disposed inferior to said balloon and a segment of said tracheal/endotracheal device is disposed superior to said balloon
c. delivering a mist through a port in said tracheal/endotracheal device, said mist being released in and delivered to the trachea, in an area that is inferior to said balloon;
d. simultaneously with the delivery step c, providing suction to capture mist or fluid from said inferior area in said trachea; and
e. delivering captured mist or fluid to a collection vessel that is disposed outside of said trachea,
wherein the provision of suction commences prior to the delivery of the mist and wherein the delivery of the mist is synchronized with the expulsion of air from the patient's lungs.

US Pat. No. 10,188,815

LARYNGEAL MASK WITH RETRACTABLE RIGID TAB AND MEANS FOR VENTILATION AND INTUBATION

Medcom Flow S.A., Barcel...

1. A laryngeal mask comprising the following elements:a rigid tube essentially in the form of a “J”, which has a lengthwise opening along its entire length; and
a flexible tube, also essentially in the form of a “J”, configured to be housed in the lengthwise opening of the rigid tube and separable from the rigid tube, and terminating at its distal end with an inflatable or gel laryngeal ring;
wherein the rigid tube terminates at its distal end with a rigid tongue-shaped tab, and wherein the flexible tube terminates at its distal end with a flexible sleeve configured to house the rigid tongue-shaped tab of the rigid tube in the interior of the flexible sleeve when the rigid tube and the flexible tube are coupled.

US Pat. No. 10,188,788

SYSTEM AND METHODS FOR MEDICAMENT INFUSION

Medirio S.A., Visp (CH)

1. A system for trans-dermal delivery of a dose of a medicament, comprising a delivery device and a separate hand-held drive device, whereinthe delivery device is configured to be placed in dermal contact with a patient, the delivery device comprising
a reservoir for holding the medicament to be delivered,
a trans-dermal injection element for delivering the dose of the medicament to the patient,
a control unit for controlling the transformation of external energy transferred from the hand-held drive device to the delivery device into a pumping force and for allowing a specific dose of the medicament to be pumped when the dose is requested, the control unit comprising
one or more rotors and/or one or more axial pump elements for transforming rotational and/or axial force into the pumping force, and
at least one safe-lock mechanism for preventing mechanical action to cause rotation of the at least one or more rotors and/or movement of the one or more axial pump elements thereby preventing passage of the medicament from the reservoir to the trans-dermal injection element unless a dose is requested;
the separate hand-held drive device being configured to be placed temporarily in proximity to the delivery device when a dose of medicament is required, the hand-held drive device comprising an activation unit for activating the control unit of the delivery device, the activation unit comprising
at least one unlocking element to provide energy to the control unit of the delivery device for unlocking the at least one safe-lock mechanism and a drive unit to provide energy for any of the one or more rotors and/or one or more axial pump elements of the control unit, only when the separate hand-held drive device is in proximity to the delivery device, and
wherein the hand-held drive device comprises a sensor capable of detecting the amount of energy being transferred and/or transformed into pumping force.

US Pat. No. 10,188,746

PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF

MEDIMMUNE LIMITED, Cambr...

1. A conjugate of formula (A):
and salts and solvates thereof, wherein:
D represents either group D1 or D2:

the dotted line indicates the optional presence of a double bond between C2 and C3;
when there is a double bond present between C2 and C3, R2 is selected from the group consisting of:
(ia) C5-10 aryl group, optionally substituted by one or more substituents selected from the group comprising: halo, nitro, cyano, ether, carboxy, ester, C1-7 alkyl, C3-7 heterocyclyl and bis-oxy-C1-3 alkylene;
(ib) C1-5 saturated aliphatic alkyl;
(ic) C3-6 saturated cycloalkyl;
(id)
wherein each of R31, R32 and R33 are independently selected from H, C1-3 saturated alkyl, C2-3 alkenyl, C2-3 alkynyl and cyclopropyl, where the total number of carbon atoms in the R2 group is no more than 5;(ie)
wherein one of R35a and R35b is H and the other is selected from: phenyl, which phenyl is optionally substituted by a group selected from halo, methyl, methoxy; pyridyl; and thiophenyl; and(if)
where R34 is selected from: H; C1-3 saturated alkyl; C2-3 alkenyl; C2-3 alkynyl; cyclopropyl; phenyl, which phenyl is optionally substituted by a group selected from halo, methyl, methoxy; pyridyl; and thiophenyl;(ig) halo;
when there is a single bond present between C2 and C3,
R2 is
where R36a and R36b are independently selected from H, F, C1-4 saturated alkyl, C2-3 alkenyl, which alkyl and alkenyl groups are optionally substituted by a group selected from C1-4 alkyl amido and C1-4 alkyl ester; or, when one of R16a and R16b is H, the other is selected from nitrile and a C1-4 alkyl ester;R6 and R9 are independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR?, NO2, SnMe3 and halo;
either
(a) R10 is H, and R11 is OH or ORA, where RA is C1-4 alkyl; or
(b) R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are bound; or
(c) R10 is H and R11 is OSOZM, where z is 2 or 3 and M is a monovalent pharmaceutically acceptable cation; or
(d) R11 is OH or ORA, where RA is C1-4 alkyl and R10 is selected from:
where Rz is selected from:(z-i)

(z-ii) OC(?O)CH3;
(z-iii) NO2;
(z-iv) OMe;
(z-v) glucoronide;
(z-vi) —C(?O)—X1—NHC(?O)X2—NH—RZC, where —C(?O)—X1—NH— and —C(?O)—X2—NH— represent natural amino acid residues and Rzc is selected from Me, OMe, OCH2CH2OMe;
Y is selected from formulae A1 and A2:

Z1 is a C1-3 alkylene group;
Z2 is a C1-3 alkylene group;
Q is:
where QX is such that Q is an amino-acid residue, a dipeptide residue or a tripeptide residue;L is a linker connected to a cell binding agent;
CBA is the cell binding agent;
n is an integer between 0 and 48;
R and R? are each independently selected from optionally substituted C1-12 alkyl, C3-20 heterocyclyl and C5-20 aryl groups, and optionally in relation to the group NRR?, R and R? together with the nitrogen atom to which they are attached form an optionally substituted 4-, 5-, 6- or 7-membered heterocyclic ring;
R8 is either:
(a) independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR?, NO2, SnMe3 and halo; or
(b) of formula A*:
wherein:D? represents either group D?1 or D2:

wherein the dotted line indicates the optional presence of a double bond between C2? and C3?;
R17 is independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR?, NO2, SnMe3 and halo;
R? is a C3-12 alkylene group, which chain may be interrupted by one or more heteroatoms, e.g. O, S, N(H), NMe and/or aromatic rings, e.g. benzene or pyridine, which rings are optionally substituted; and
X and X? are independently selected from O, S and N(H); and
R22, R16, R19, R20 and R21 are as defined for R2, R6, R9, R10 and R11 respectively.

US Pat. No. 10,188,743

CYTISINE-LINKED ISOFLAVONOID ANTINEOPLASTIC AGENTS FOR THE TREATMENT OF CANCER

University of Kentucky Re...

1. A method of treating prostate or colorectal cancer, the method comprising administering to a patient in need of prostate or colorectal cancer treatment an effective amount of a cytisine-linked isoflavonoid compound represented by formula (I):
or pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof,
wherein Ar is an aryl or heteroaryl; n is an integer from 1 to 5; each X is independently a halide, or alkoxy, or more than one X on Ar together form a cyclic ether structure; and wherein the compound is substituted on the C-2 position with H, alkyl, cycloalkyl or alkoxy, substituted on the C-5, C-6, C-7, and C-8 positions independently with H, hydroxy (OH), alkyl, cycloalkyl, alkoxy, L is a substituted or unsubstituted di-radical linker group that links the cytisinyl group to either the C-5, C-6, C-7 or C-8 position.

US Pat. No. 10,188,677

IRON SUPPLEMENT COMPOSITION

THE D DROPS COMPANY INC.,...

1. A composition consisting of:a non-encapsulated iron salt; and
a carrier of a digestible edible oil that is a liquid at 20° C.

US Pat. No. 10,188,618

TREATMENT OF CANCER WITH SPECIFIC RXR AGONISTS

IO Therapeutics, Inc., S...

1. A method of treating a hematologic malignancy, wherein the hematologic malignancy is a leukemia or a lymphoma, comprising administering to a patient in need of such treatment a retinoid X receptor (RXR) agonist at a dose below its Retinoic Acid Receptor (RAR) activating threshold and at or above its RXR effective dose, the RXR agonist has a chemical structure
where R is H, lower alkyl or 1 to 6 carbons, or a pharmaceutically acceptable salt of the compound, and the dose of the RXR agonist is from about 0.1 to about 20 mg/m2/day.

US Pat. No. 10,188,570

METHOD OF REDUCING SURGEON FATIGUE DURING AN OPERATION WHILE REDUCING COLLECTION OF FLUIDS FROM THE OPERATION ON THE FLOOR OF THE OPERATING ROOM BY ABSORBING FLUIDS LEAKING ONTO THE FLOOR OF THE OPERATING ROOM AND APPARATUS THEREFOR

XODUS MEDICAL, INC., , PA...

1. An absorbent, anti-fatigue operating room mat comprising:a support layer to be disposed on the floor of an operating room during performance of an operating room procedure;
a fluid-resistant layer being disposed on top of said support layer during performance of an operating room procedure;
a fluid-absorbent layer being disposed on top of said fluid-resistant layer during performance of an operating room procedure;
a shock-absorbing layer being disposed on top of said fluid-absorbent layer during performance of an operating room procedure;
said shock-absorbing layer comprising shock-absorbing foam material to absorb shocks and reduce fatigue on operating room personnel standing on said anti-fatigue operating room mat;
said shock-absorbing layer comprising holes to permit passage of operating room fluids, generated during performance of an operating room procedure, through said shock-absorbing layer and to said fluid-absorbent layer;
said fluid-absorbent layer comprising a fluid-absorbent material to absorb, capture, contain, and retain operating room fluids that pass through said holes in said shock-absorbing layer to thereby minimize deposition of the operating room fluids on the floor of an operating room;
said fluid-resistant layer comprising a fluid-resistant material to resist the passage of operating room fluids, not absorbed by said fluid-absorbent layer, through and out of said anti-fatigue operating room mat; and
said support layer comprising an anti-skid material to minimize or prevent unwanted sliding or skidding of the anti-fatigue operating room mat on the floor of an operating room during performance of an operating room procedure.

US Pat. No. 10,188,551

SYSTEMS AND METHODS FOR DELIVERING AN OCULAR IMPLANT TO THE SUPRACHOROIDAL SPACE WITHIN AN EYE

GLAUKOS CORPORATION, San...

1. An ocular implant delivery system, comprising:a generally elongated outer housing;
an elongated insertion needle partially disposed in and extending outwardly from the outer housing, the insertion needle having a lumen;
a pusher tube assembly comprising an implant pusher tube and a pusher tube collar fixedly attached to a proximal portion of the implant pusher tube, a distal portion of the implant pusher tube extending through the lumen of the insertion needle;
a trocar assembly comprising a trocar and a trocar collar fixedly attached to a proximal portion of the trocar, a distal portion of the trocar passing through a lumen of the implant pusher tube;
an implant supported on the distal portion of the trocar, wherein a distal tip of the trocar extends distally beyond a distal-most end of the implant when the implant is supported on the distal portion of the trocar; and
a trocar trigger mechanically coupled to the trocar assembly such that a first actuation of the trocar trigger causes the trocar assembly to move the pusher tube assembly distally relative to the insertion needle to a distal locked position, wherein the implant is exposed from the insertion needle for implantation in a suprachoroidal space of an eye when the pusher tube assembly is at the distal locked position, the trocar trigger being further configured such that a second actuation of the trocar trigger causes the distal tip of the trocar to move proximal to the distal-most end of the implant, thereby releasing the implant from being supported on the distal portion of the trocar.

US Pat. No. 10,188,540

SACROILIAC BELT

BRACE FIT LLC, Owariasah...

1. A sacroiliac belt comprising a belt pair that forms a pelvic holding loop to hold a user's pelvis from a buttock side or a lumbar back side, entirely wrapping the pelvis, the belt pair comprising:a ring-shaped ilium belt (A) configured to be wound around the user's waist, surrounding the user's right and left ilia; and
a second belt selected from:
either a buttock belt (B1) configured to be wound around the user's waist passing under the user's buttocks, lifting up the buttocks; or
a lumbar belt (B2) configured to be wound around the user's waist passing the user's lumbar back, which is a back side of the user's lumbar curve located immediately above the pelvis, wherein:
the second belt is shorter than the ilium belt,
the sacroiliac belt comprises rings at both ends of the second belt,
while the ilium belt placed through the rings, the both ends of the second belt each connected to the ilium belt in a pair of connection areas placed inside both ends of the ilium belt through a reversible connection through which the both ends of the second belt are reversibly connected to the pair of connection areas on the ilium belt via touch fasteners that consist of first and second components, the first components attached in the connection areas on the ilium belt, the second components attached on the both ends of the second belt the first components have widths within which positions of connection between the first and second components are adjustable,
the second belt comprises:
a band-shaped main portion;
the rings, and
a pair of connection portions each comprising the second components of the touch fasteners, and connected to both ends of the main portion via the rings,the both ends of the main portion and the connection portions each attached to the rings in a movable manner along rims of the rings, andthe rings are placed more inside the both ends of the second belt than the second components are.

US Pat. No. 10,188,513

PROSTHETIC TISSUE VALVES

CORMATRIX CARDIOVASCULAR,...

1. A prosthetic valve for modulating fluid flow through a cardiovascular structure during cardiac cycles of a heart, said fluid flow exhibiting a plurality of positive and negative flow pressures during said cardiac cycles, said prosthetic valve comprising:a valve structure comprising a remodelable conical shaped sheet member, said sheet member comprising an extracellular matrix (ECM) composition, said ECM composition comprising acellular ECM from a mammalian tissue source,
said sheet member further comprising an open proximal annulus engagement end configured to engage said cardiovascular structure and receive said fluid flow therein and a closed distal end,
said sheet member further comprising a plurality of linear interstices disposed between said sheet member open proximal annulus engagement end and said closed distal end, wherein said plurality of linear interstices do not extend to said closed distal end,
said sheet member being configured to transition from an expanded position when said proximal annulus engagement end of said sheet member is engaged to said cardiovascular structure and receives said fluid flow therein, and said fluid flow exhibits a first positive flow pressure of said plurality of positive flow pressures, to a collapsed position when said fluid flow exhibits a first negative flow pressure of said plurality of negative flow pressures,
said plurality of linear interstices being configured to transition from an open position, when said sheet member is in said expanded position, to a closed position, when said sheet member is in said collapsed position,
said closed distal end of said sheet member being configured to block said fluid flow therethrough when said plurality of linear interstices are in said open and closed positions, wherein when said plurality of linear interstices are in said open position, said plurality of linear interstices allow said fluid flow to be transmitted through said plurality of linear interstices and sheet member, and wherein when said plurality of linear interstices are in said closed position, said plurality of linear interstices and said closed distal end of said sheet member jointly block said fluid flow through said sheet member,
said sheet member being further configured to remodel, and induce host cell and tissue proliferation, remodeling of damaged cardiovascular tissue and regeneration of new cardiovascular tissue and tissue structures with site-specific structural and functional properties, when said proximal annulus engagement end of said sheet member is engaged to said cardiovascular structure, wherein said proximal annulus engagement end of said sheet member is disposed proximate damaged tissue of said cardiovascular structure; and
a biodegradable multi-link support stent structure disposed in said sheet member.

US Pat. No. 10,188,510

PROSTHETIC TISSUE VALVES

CorMatrix Cardiovascular,...

1. A prosthetic valve for modulating fluid flow through a cardiovascular structure during cardiac cycles of a heart, said fluid flow exhibiting a plurality of positive and negative flow pressures during said cardiac cycles, said prosthetic valve comprising:a remodelable biological tissue structure comprising a continuous tubular member,
said tubular member comprising an adaptive tissue regeneration system configured to engage said cardiovascular structure and induce modulated healing of damaged cardiovascular tissue of said cardiovascular structure concomitantly with stress-induced hypertrophy of said tubular member when said tubular member is subjected to cardiac cycle induced physical stimuli,
said modulated healing of said damaged cardiovascular tissue comprising inflammation modulation of said damaged cardiovascular tissue and induced neovascularization, remodeling of said damaged cardiovascular tissue and regeneration of new cardiovascular tissue and tissue structures with site-specific structural and functional properties,
said stress-induced hypertrophy of said tubular member comprising adaptive remodeling of said tubular member, wherein said tubular member remodels and forms functioning valve structures that are similar to native valve structures,
said adaptive tissue regeneration system comprising a tubular member material component and a tubular member physical structure component,
said tubular member material component comprising an extracellular matrix (ECM) composition, said ECM composition comprising acellular ECM from a mammalian tissue source,
said tubular member physical structure component comprising a sheet member comprising a proximal valve annulus engagement end and a distal end, said proximal valve annulus engagement end of said sheet member being configured to engage a valve annulus region of said cardiovascular structure,
said proximal valve annulus engagement end comprising a circumferential ribbon connection region and a plurality of equally spaced ribbons projecting from said circumferential ribbon connection region toward said sheet member distal end,
each of said plurality of ribbons comprising proximal and distal ends, a first edge region extending from said proximal end of each of said plurality of ribbons to said distal end of each of said plurality of ribbons and a second edge region extending from said proximal end of each of said plurality of ribbons to said distal end of each of said plurality of ribbons,
said proximal end of each of said plurality of ribbons being connected to said circumferential ribbon connection region,
said plurality of ribbons being positioned circumferentially about said circumferential ribbon connection region, wherein said first edge regions of said plurality of ribbons are positioned proximate said second edge regions of said plurality of ribbons, wherein a plurality of fluid flow modulating regions is formed between adjacent ribbons of said plurality of ribbons,
said distal ends of said plurality of ribbons being engaged to each other in a joined relationship, wherein fluid flow through said sheet member at said joined distal ends of said plurality of ribbons is restricted while said fluid flow is allowed to be transmitted through said fluid flow modulating regions when in an open position,
said sheet member being configured to transition from an expanded position when said proximal valve annulus engagement end of said sheet member is engaged to said valve annulus region of said cardiovascular structure and receives said fluid flow therein, and said fluid flow exhibits a first positive flow pressure of said plurality of positive flow pressures, to a collapsed position when said fluid flow exhibits a first negative flow pressure of said plurality of negative flow pressures,
said plurality of fluid flow modulating regions being configured to transition from said open position when said sheet member is in said expanded position, wherein said plurality of fluid flow modulating regions allow said fluid flow to be transmitted through said sheet member, to a closed position when said sheet member is in said collapsed position, wherein said plurality of fluid flow modulating regions restrict said fluid flow through said sheet member.

US Pat. No. 10,188,509

PROSTHETIC TISSUE VALVES

CORMATRIX CARDIOVASCULAR,...

1. A prosthetic valve for modulating fluid flow through a cardiovascular structure during cardiac cycles of a heart, said fluid flow exhibiting a plurality of positive and negative flow pressures during said cardiac cycles, said prosthetic valve comprising:a remodelable biological tissue structure comprising a conical shaped sheet member, said sheet member comprising an extracellular matrix (ECM) composition, said ECM composition comprising acellular ECM from a mammalian tissue source,
said sheet member further comprising an open proximal annulus engagement end configured to engage said cardiovascular structure and receive said fluid flow therein and a closed distal end,
said sheet member further comprising a plurality of linear interstices disposed between said sheet member open proximal annulus engagement end and said closed distal end, wherein said plurality of linear interstices do not extend to said closed distal end,
said sheet member being configured to transition from an expanded position when said proximal annulus engagement end of said sheet member is engaged to said cardiovascular structure and receives said fluid flow therein, and said fluid flow exhibits a first positive flow pressure of said plurality of positive flow pressures, to a collapsed position when said fluid flow exhibits a first negative flow pressure of said plurality of negative flow pressures,
said plurality of linear interstices being configured to transition from an open position, when said sheet member is in said expanded position, to a closed position, when said sheet member is in said collapsed position,
said closed distal end of said sheet member being configured to block said fluid flow therethrough when said plurality of linear interstices are in said open and closed positions, wherein when said plurality of linear interstices are in said open position, said plurality of linear interstices allow said fluid flow to be transmitted through said plurality of linear interstices and said sheet member, and wherein when said plurality of linear interstices are in said closed position, said plurality of linear interstices and said distal end of said sheet member jointly block said fluid flow through said sheet member,
said sheet member being further configured to remodel, and induce host cell and tissue proliferation, remodeling of damaged cardiovascular tissue and regeneration of new cardiovascular tissue and tissue structures with site-specific structural and functional properties, when said proximal annulus engagement end of said sheet member is engaged to said cardiovascular structure, wherein said proximal annulus engagement end of said sheet member is disposed proximate damaged tissue of said cardiovascular structure.

US Pat. No. 10,188,500

STENT GRAFT WITH EXTERNAL SCAFFOLDING AND METHOD

Medtronic Vascular, Inc.,...

1. A scaffolded stent-graft comprising:a hydrophobic graft material comprising an inner surface and an outer surface, the inner surface defining a lumen within the graft material, the graft material being hostile to tissue ingrowth therein; and
a scaffold comprising a metallic material mesh comprising openings therein coupled to the graft material at the outer surface, the scaffold configured to promote tissue ingrowth therein, the scaffold comprising a metal to artery ratio optimized to create stasis of blood within the scaffold resulting in thrombus formation, wherein the mesh is in the shape of a torus.

US Pat. No. 10,188,496

VENA CAVA FILTER FORMED FROM A SHEET

C. R. BARD, INC., Murray...

1. A blood filter for use in a patient's blood vessel having a vessel wall surrounding a vessel lumen, comprising:a) a longitudinally extending filter body including a proximal section extending a first fixed distance from a proximal terminal end of the longitudinal filter body to a first intermediate endpoint, said proximal section having a first cross-sectional area;
b) a distal section having a distal terminal end and a second cross-sectional area;
c) a joining section positioned between the proximal and distal sections and having a third cross-sectional area less than both the first and second cross-sectional areas;
d) said joining section spaced away from each of said terminal ends and extending a fixed second distance;
e) a first hub on said joining section that is slidable a fixed distance along a length of said joining section and in between said proximal and distal sections while in use in the blood vessel;
f) a plurality of appendages, each attached to said hub at an inner appendage end portion, each appendage having an outer appendage end portion providing unattached distal-most ends extending radially outward of said hub;
g) wherein said appendages are bendable in both a proximal and distal direction, thus enabling insertion of said filter body with hub and appendages using either a jugular access site or a femoral access site; and
h) wherein said filter body, said hub and said appendages are configured to occupy a vessel of a patient.

US Pat. No. 10,188,490

METHODS AND SYSTEMS FOR DENTAL PROCEDURES

Align Technology, Inc., ...

1. A method for digitally aligning a patient's teeth with a reference portion of the patient, the method comprising:acquiring, using a scanner, a first image of at least a portion of the patient's teeth;
positioning a device in a patient's mouth to align the device with a reference portion of the patient, the device comprising an occlusal portion and a non-occlusal portion, the occlusal portion comprising a bite plate held between the patient's teeth so as to secure the device in a position during a scanning procedure and the non-occlusal portion comprising a coded pattern for aligning scanned images of the patient, the occlusal portion and the non-occlusal portion being coupled together at an angle such that the coded pattern is outwardly oriented from the patient's mouth when the bite plate is positioned between the patient's teeth, so that the coded pattern is presented to permit scanning of the coded pattern simultaneously when scanning at least the portion of the patient's teeth;
acquiring, using the scanner, a second image of at least a portion of the coded pattern and at least the portion of the patient's teeth: and
processing the first image and the second image to determine a spatial relationship between at least the portion of the patient's teeth and the reference portion by calculating a first spatial relationship between at least the portion of the coded pattern and at least the portion of the patient's teeth and the alignment between the device and the reference portion.

US Pat. No. 10,188,457

SELECTABLE ECCENTRIC REMODELING AND/OR ABLATION

Vessix Vascular, Inc., L...

1. An apparatus comprising:a catheter configured for intravascular placement within a blood vessel of a human patient;
an expandable balloon at a distal portion of the catheter, wherein the expandable balloon is configured to vary between a delivery configuration and a deployed configuration sized to fit within the blood vessel;
a first pair of bipolar contacts attached to the expandable balloon; and
a second pair of bipolar contacts attached to the expandable balloon,
wherein the first pair of bipolar contacts and the second pair of bipolar contacts are spaced apart lengthwise and angularly offset from one another when the expandable balloon is in the deployed configuration,
wherein each of the first pair of bipolar contacts and the second pair of bipolar contacts is configured to deliver thermal energy to less than a full circumference of the blood vessel of the patient.

US Pat. No. 10,188,436

INFLATABLE MEDICAL DEVICES

LOMA VISTA MEDICAL, INC....

1. A device for delivering a material to an orthopedic target site comprising:a flexible tube having a first lumen having a first end and a second end;
a pusher having a pusher total length between a pusher first end and a pusher second end, wherein the pusher comprises a pusher first length and a pusher second length, wherein the pusher first length has a first rigidity and the pusher second length has a second rigidity, said pusher comprising a first member spanning the first length and the second length, and a stiffening sheath spanning an entirety of only the first length; and
wherein the first rigidity is greater than the second rigidity; and
wherein the pusher and tube are configured for the pusher to be slidably received by the first end of the first lumen; and
wherein the material is located in the first lumen between the pusher and the second end.

US Pat. No. 10,188,423

MULTI-PIECE GIMBAL RING

HeartWare, Inc., Miami L...

16. A mounting structure for connecting a device to the heart, the mounting structure comprising:a mounting ring defining a bore, the mounting ring being adapted for mounting to an exterior surface of the heart of a living subject, the mounting ring including a collar having a deformable wall defining a main bore;
a clamp engaged with the collar, the clamp being arranged to deform the collar so as to constrict the main bore;
a gimbal ring disposed within the main bore, the gimbal ring defining a gimbal bore co-axial with the main bore and including a plurality of separate arcuate elements cooperatively disposed in a circumferential direction around the gimbal bore, the plurality of separate arcuate elements being rigid and movable toward one another to constrict the gimbal bore;
a deformable tube, the deformable tube defining a one-way valve and being more readily deformable than the plurality separate of arcuate elements, the deformable tube being configured to connect the plurality of separate arcuate elements with one another;
each of the plurality of separate arcuate elements includes a slot at a first end and a projection at the opposite second end, and at least one of the plurality of arcuate elements is slideably engaged with at least one other of the plurality of arcuate elements to provide movement relative to one another in the circumferential direction; and
the plurality of separate arcuate elements being movable from an unconstricted condition in which a gap is defined between adjacent arcuate element and a constricted condition in which the gaps are closed.

US Pat. No. 10,188,407

DRILL GUIDE FOR ACETABULAR CUP FASTENERS

HIP INNOVATION TECHNOLOGY...

1. A surgical tool system adapted for drilling holes in an acetabulum to accommodate screws used to fasten an acetabular cup to the acetabulum, the acetabular cup comprising a concave portion having a stem extending from the bottom thereof, cup slots disposed in the concave portion in close proximity to a circumferential edge of the acetabular cup and one or more through holes to accommodate screws for fastening the acetabular cup to the acetabulum, the surgical tool system comprising:a drill guide sized to fit within the concave portion and having spring-loaded pins arranged to engage the cup slots when the drill guide is optimally positioned within the acetabular cup, the drill guide further comprising one or more through holes sized and spaced to line up approximately concentrically with the through holes of the acetabular cup and a guide indent for each hole, each guide indent being positioned on a beam member which traverses the drill guide at a circumferential edge thereof;
a handle comprising a shaft with a drill bit guide disposed at the distal end thereof, the drill bit guide having a drill bit guide distal end and a side portion, the drill bit guide being sized to engage a hole and the side portion being positioned to engage the guide indent for its respective hole; and
a drill bit having a cutting portion and a shaft sized to pass through the drill bit guide.

US Pat. No. 10,188,377

SEMI-AUTOMATIC SUTURING MACHINE

Ruchi Patel, Princeton J...

1. A suturing device comprising:a. a driver arm and receiver arm, each comprising a distal end and a proximal end, said driver and receiver arms connected by a hinge at their proximal ends, said hinge being configured to allow said distal ends of said driver arm and said receiver arm to converge and separate through rotation about said hinge while keeping said proximal ends of both arms affixed to each other;
b. one or more suture units capable of securing wound tissue housed in a crimped anchor loading system, said suture units comprising a length of suture material having a proximal end and a distal end, a fixed anchor attached to said proximal end of the suture, and a needle attached to the distal end of the suture;
c. a center assembly attached to the distal end of the receiver arm and in communication with the driver arm, said center assembly comprising, a suture unit loading system, the crimped anchor loading system, a crimped anchor fastening system, and needle disposing system;
d. wherein the driver arm and receiver are configured to be actuated to engage a gear system within the center assembly, thereby driving a suture unit through two edges of tissue until the fixed anchor abuts against the tissue, securing said edges of tissue by fastening a crimped anchor onto the distal end of the suture, disjoining the distal end of the suture from the needle; disposing of the needle.

US Pat. No. 10,188,356

RADIATION SYSTEMS

VARIAN MEDICAL SYSTEMS, I...

1. A radiation system, comprising:a treatment device having a structure, and a first radiation source coupled to the structure, wherein the first radiation source is configured to rotate about an axis and to deliver a treatment radiation beam;
a rail system associated with the structure; and
a MRI device moveably coupled to the rail system;
wherein the rail system is configured to guide the MRI device from a first position to a second position, the second position being closer to the treatment device than the first position;
wherein the treatment device is at an operative position for delivering the treatment radiation beam; and
wherein when the treatment device is at the operative position, and when the MRI device is at the second position, the MRI device is next to the treatment device so that a spacing between the MRI device and treatment device is less than a thickness of the MRI device or the treatment device, and the MRI device is behind the treatment device along the axis.

US Pat. No. 10,188,355

BACKGROUND-SUPPRESSED, REDUCED FIELD-OF-VIEW RADIAL MAGNETIC RESONANCE IMAGING

Siemens Healthcare GmbH, ...

1. A computer-implemented magnetic resonance imaging (MRI) method for acquiring images of a patient, the method comprising:receiving, by an input processor, user input comprising an indication of a field of view (FOV) that encompasses only an anatomy of interest of the patient, the anatomy of interest smaller than a full dimension of the patient;
shimming, by a processor configured to communicate with the input processor, on the anatomy of interest within the FOV;
applying, by the processor, a radial quiescent-interval slice-selective (QISS) pulse sequence including a magnetization preparation pulse to the shimmed FOV to acquire images of the anatomy of interest; and
generating, at a display processor configured to communicate with the processor, data representing the acquired images of the anatomy of interest.

US Pat. No. 10,188,335

PLASMA OR SERUM PRODUCTION AND REMOVAL OF FLUIDS UNDER REDUCED PRESSURE

Seventh Sense Biosystems,...

21. A device for receiving blood from a subject and processing the blood to form plasma or serum, the device comprising:an inlet for introduction of a bodily fluid from the subject into the device;
a storage chamber for receiving plasma or serum;
a first membrane that is substantially impermeable to cells, wherein the first membrane separates the inlet from the storage chamber and is capable of separating blood passing through to produce a portion enriched in plasma or serum;
a vacuum chamber, separate from the storage chamber, having a pressure less than ambient pressure; and
a second membrane that is gas permeable but is substantially liquid impermeable, wherein the second membrane separates the storage chamber from the vacuum chamber.

US Pat. No. 10,188,332

METHOD AND SYSTEM FOR SENSING GLUCOSE CONCENTRATION

NATIONAL CHENG KUNG UNIVE...

1. A system for sensing glucose concentration, the system comprising:a light source configured to generate a light beam;
a polarization state generator configured to receive the light beam, wherein the polarization state generator comprises a modulator for changing a polarization of the light beam, and the light beam passing the modulator is emitted to a biological tissue;
a polarization state analyzer configured to receive the light beam reflected from the biological tissue; and
a controlling module configured to transmit an electrical signal to the modulator, wherein the electrical signal has n sampling points which correspond to n polarizations of the light beam respectively, the n polarizations are different from each other, and n is a positive integer greater than or equal to 4,
wherein for each of the n sampling points, the controlling module calculates a Stokes vector according to the light beam received by the polarization state analyzer,
wherein the controlling module calculates a Mueller matrix according to the Stokes vectors corresponding to the n sampling points, and calculates at least one parameter according to the Mueller matrix, wherein the at least one parameter comprises a depolarization index or an optical rotation angle,
wherein the controlling module calculates a glucose concentration corresponding to the biological tissue according to the at least one parameter.

US Pat. No. 10,188,327

PORTABLE CLINICAL ANALYSIS SYSTEM FOR HEMATOCRIT MEASUREMENT

Abbott Point of Care Inc....

1. A method of performing a hematocrit analysis, the method comprising:inserting a test device comprising a hematocrit sensor into a port of an analyzer;
initiating, by the analyzer, a test cycle of the test device, the test cycle including performance of the hematocrit analysis, wherein the performance of the hematocrit analysis includes the test device generating an electric signal based on a hematocrit measurement of a biological sample;
determining spatial orientation and/or motion of the analyzer during the test cycle of the test device;
comparing the determined spatial orientation to a threshold operating spatial plane for the test device and/or comparing the determined motion to a threshold rate of motion for the test device;
when the determined spatial orientation exceeds the threshold operating spatial plane, and/or the determined motion exceeds the threshold rate of motion, providing an alert prompting a user to take corrective action,
wherein the corrective action is instructed in the alert to be taken during the test cycle without having to reinitiate the test cycle including the performance of the hematocrit analysis.

US Pat. No. 10,188,324

INFORMATION PROCESSING DEVICE, SENSOR DEVICE, INFORMATION PROCESSING SYSTEM, AND STORAGE MEDIUM

SONY CORPORATION, Tokyo ...

1. An information processing system comprising:a shock sensor;
processing circuitry configured to, for each of plural shock events,
receive input data from the shock sensor which outputs data defining a respective shock event,
receive time-series data output from a motion sensor that senses motion of an object, the shock sensor having a greater dynamic range in acceleration than the motion sensor,
set a length of a pre-shock portion of a target segment of the time-series data as a length of the longest pre-shock portion among plural predetermined motion patterns,
set a length of a post-shock portion of the target segment as a length of the longest post-shock portion among the plural predetermined motion patterns,
identify the target segment according to the defined respective shock event and the set lengths of the pre-shock portion and the post-shock portion,
identify an impact position on the object, and
identify the motion of the object as one of the plural predetermined motion patterns based on the identified target segment of the time-series data and a stored dictionary defining each of the plural predetermined motion patterns; and
a display configured to notify a user of the identified one of the plural predetermined motion patterns and display an impact position indicator on the object which is in an orientation corresponding to an actual orientation of the object at a time of impact based on the identified one of the plural predetermined motion patterns and the identified impact position.

US Pat. No. 10,188,318

BREATH DELIVERY SYSTEM AND METHOD

Invoy Holdings, LLC, Ali...

1. A mouthpiece for use with a portable electronic analyzer for detecting an analyte in a breath sample from an individual, the mouthpiece comprising:a biosensor that detects the analyte and generates a signal, the biosensor including a chemically active area where a chemical reaction takes place;
a processor, the processor configured to communicate with the biosensor;
a hydration system that is activated by the processor and then causes a plunger to release a liquid to the chemically active area of the biosensor to at least one of enhance, enable, and facilitate the chemical reaction;
a liquid sensor that determines if the liquid was delivered to the chemically active area, the liquid sensor configured to communicate with one or more of the biosensor, the processor, and the hydration system; and
hardware that transmits breath analyte data to the electronic analyzer.

US Pat. No. 10,188,309

SYSTEMS, ARTICLES, AND METHODS FOR ELECTROMYOGRAPHY SENSORS

NORTH INC., Kitchener (C...

1. A differential electromyography (“EMG”) sensor comprising:a first sensor electrode formed of an electrically conductive material;
an amplifier;
a first electrically conductive pathway that communicatively couples the first sensor electrode and the amplifier;
a first capacitor electrically coupled in series between the first sensor electrode and the amplifier in the first electrically conductive pathway;
a first resistor electrically coupled in series between the first sensor electrode and the amplifier in the first electrically conductive pathway;
a ground electrode formed of an electrically conductive material;
a second electrically conductive pathway that communicatively couples to the ground electrode;
a third electrically conductive pathway that communicatively couples the first electrically conductive pathway and the second electrically conductive pathway;
a second capacitor electrically coupled in the third electrically conductive pathway in between the first electrically conductive pathway and the second electrically conductive pathway;
a fourth electrically conductive pathway that communicatively couples the first electrically conductive pathway and the second electrically conductive pathway;
a second resistor electrically coupled in the fourth electrically conductive pathway in between the first electrically conductive pathway and the second electrically conductive pathway;
a second sensor electrode formed of an electrically conductive material;
a fifth electrically conductive pathway that communicatively couples the second sensor electrode and the amplifier;
a third capacitor electrically coupled in series between the second sensor electrode and the amplifier in the fifth electrically conductive pathway;
a third resistor electrically coupled in series between the second sensor electrode and the amplifier in the fifth electrically conductive pathway;
a sixth electrically conductive pathway that communicatively couples the fifth electrically conductive pathway and the second electrically conductive pathway;
a fourth capacitor electrically coupled in the sixth electrically conductive pathway in between the fifth electrically conductive pathway and the second electrically conductive pathway;
a seventh electrically conductive pathway that communicatively couples the fifth electrically conductive pathway and the second electrically conductive pathway; and
a fourth resistor electrically coupled in the seventh electrically conductive pathway in between the fifth electrically conductive pathway and the second electrically conductive pathway.

US Pat. No. 10,188,303

HEMODYNAMIC MONITOR AND METHOD OF HEMODYNAMIC MONITORING

LIDCO Group PLC, London ...

1. An apparatus for determining stroke volume comprising:an input for receiving an arterial pressure waveform;
means arranged to define a start point within the arterial pressure waveform at a beginning of a systolic arterial pressure increase due to a ventricular contraction phase of a heart beat;
means arranged to determine an end point of the heart beat for the purpose of calculating stroke volume by
determining whether there is a part or point of the arterial pressure waveform that has substantially the same arterial pressure value as said starting point,
responsive to said arterial pressure value at said starting point being regained, setting the end point to be the part or point of the arterial pressure waveform that has substantially the same arterial pressure value as said starting point, and
responsive to said arterial pressure value at said starting point not being regained, extrapolating the end point of the heart beat to a point where the arterial pressure waveform has substantially the same arterial pressure value as said starting point to define the end point;
means arranged to calculate a stroke volume from a part of the arterial pressure waveform or of the extrapolated arterial pressure waveform between the start point and the end point; and
an output means and configured to output, via the output means, an indication of at least one of a current stroke volume, a current heart rate, a number of previous stroke volumes and a number of previous heart rates.

US Pat. No. 10,188,298

OPTICAL SPECULUM

Illumigyn Ltd., Neve Ila...

1. A system for direct imaging, diagnosing and removing of abnormal cells in a target tissue, comprising:a disposable optical speculum;
an image acquisition system having the speculum assembled on and mechanically secured thereto, the image acquisition system arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets;
an image analysis and control unit in communication with the image acquisition system, the image analysis and control unit analyzing the data sets and applying algorithms to the data sets for diagnosing abnormal cells; and
a detector for warning of undesired stray light generated by improper assembly of the disposable optical speculum to the image acquisition system.

US Pat. No. 10,188,296

WIRELESS PATIENT MONITORING DEVICE

Masimo Corporation, Irvi...

1. A method of wirelessly monitoring physiological information, the method comprising:providing a battery including a data storage component;
connecting the battery to a bedside monitor;
recharging the battery via the bedside monitor;
upon connecting the battery to the bedside monitor, transferring wireless communication configuration data from the bedside monitor to the data storage component via a hard wired connection;
disconnecting the battery from the bedside monitor;
connecting the disconnected battery to a wireless monitor;
powering the wireless monitor with the battery;
upon connecting the disconnected battery to the wireless monitor, transferring the wireless communication configuration data from the data storage component to the wireless monitor;
reconfiguring wireless communication parameters of the wireless monitor according to the wireless communication configuration data when the battery is connected to the wireless monitor;
establishing wireless communication between the wireless monitor and the bedside monitor using the wireless communication configuration data;
obtaining physiological information from one or more optical sensors using the wireless monitor powered by the battery; and
transmitting physiological data reflective of the physiological information from the wireless monitor to the bedside monitor.

US Pat. No. 10,188,294

ADAPTER FOR RETINAL IMAGING USING A HAND HELD COMPUTER

Verana Health, Inc., San...

1. An adapter configured to engage with a hand held computer device with a camera having an optical axis comprising:an anterior adapter portion comprising: a body, a clamp configured to engage with the hand held computer device at a first location and a second location, a lens holder engaged with a macro lens movable between a first position in the optical axis of the camera and a second position outside of the optical axis of the camera, an adjustable light source with a light axis parallel to a macro lens optical axis, a third engagement surface configured to slidably engage with the hand held computer device at a third location, and a complementary surface of the body configured to reversibly engage with a base section of a posterior portion, wherein the clamp defines an axis and the body of the anterior adapter portion is configured to move along the axis of the clamp; and
the posterior portion comprising: the base section configured to reversibly engage with the complementary surface of the body of the anterior adapter portion, a telescoping section movable relative to the base section, and a lens holder engaged with a distal end of the telescoping section configured to removably engage with an ophthalmoscopy lens, the base section configured to removably engage with the body of the anterior adapter portion to form an optical axis between the ophthalmoscopy lens and the camera of the hand held computer device.

US Pat. No. 10,188,278

USING AN INTRAORAL MIRROR WITH AN INTEGRATED CAMERA TO RECORD DENTAL STATUS, AND APPLICATIONS THEREOF

DENTAL SMARTMIRROR, INC.,...

16. A system for capturing an image representing a patient's dental status, comprising:a processor;
a patient status database that stores historical patient status information including historical panoramic images of a patient's mouth; and
a server, executed on the processor, that receives (i) a plurality of photographs of an interior of the patient's mouth, and (ii) associated position information for the respective photographs, wherein the plurality of photographs are collected from an image sensor affixed to a dental mirror, wherein the position information is collected relative to a base station capable of docking to the dental mirror, wherein the position information is determined using an accelerometer or gyroscope or both affixed to the dental mirror, wherein the accelerometer or gyroscope or both is calibrated with the dental mirror while docked to the base station, and wherein each one of the plurality of photographs overlap at least in part with another one of the plurality of photographs, the server comprising:
a panorama stitcher module that (i) determines features in the overlapping portions that match between multiple photographs, (ii) based on associated position information for the respective photographs and the matching features, aligns the plurality of photographs to represent a series of adjacent teeth, and (iii) stitches the plurality of photographs of the interior of the patient's mouth into a panoramic image representing a state of at least a portion of the patient's mouth.

US Pat. No. 10,188,273

BIOLOGICAL NAVIGATION DEVICE

LOMA VISTA MEDICAL, INC.,...

1. A device for navigation through a biological anatomy, the device comprising:a tube configured to be advanced through the biological anatomy, the tube having a tube lumen therein;
a steering portion configured to bend to orient the device, said steering portion comprising an actuator for controlling the steering portion;
a reciprocating portion comprising a first tubular reciprocating element and a second tubular reciprocating element, the first tubular reciprocating element attached to a distal end of the steering portion, the second tubular reciprocating element mounted to and surrounding the first tubular reciprocating element, wherein an entirety of the second tubular reciprocating element is configured to longitudinally translate relative to the first tubular reciprocating element, wherein the second tubular reciprocating element remains coaxial with the first tubular reciprocating element during longitudinal translation of the second tubular reciprocating element relative to the first reciprocating element;
a visualization element for visualizing the biological anatomy; and
a distal tip at a distal end of the second tubular reciprocating element having a tip lumen therein continuous with the tube lumen, the tip lumen configured to hold the visualization element therein;
wherein longitudinal translation of the second tubular reciprocating element causes corresponding longitudinal translation of the visualization element held within the tip lumen of the distal tip.

US Pat. No. 10,188,254

AUTONOMOUS PLANAR SURFACE CLEANING ROBOT

ECOVACS ROBOTICS, INC., ...

1. A planar surface cleaning apparatus, comprising:a main body having a top portion and a bottom portion, the bottom portion defining an outer portion defining a surface area about a perimeter thereof and an inner portion defining a cavity formed within the outer portion;
at least one vacuum source supported by the main body and in fluid communication with the cavity;
a cleaning component disposed over the surface area defined on the outer portion of the bottom portion of the main body; and
a connector pole comprising:
a handle portion; and
a U portion connected to the handle portion, wherein the U portion is pivotally connected to the main body.

US Pat. No. 10,188,241

DISPENSER ASSEMBLY

Vi-Jon, Inc., St. Louis,...

1. A dispenser assembly for dispensing a product, the dispenser assembly comprising:a bottle configured to store the product, the bottle comprising a back wall, the back wall comprising:
a substantially flat surface;
an angled surface extending outwards from the flat surface; and
an extension portion extending outwards from the flat surface, the extension portion having a width less than a width of the flat surface; and
a battery holder, the battery holder comprising:
a housing; and
a plurality of batteries contained in the housing,
wherein the battery holder is positioned adjacent the flat surface of the back wall of the bottle and below the angled surface of the back wall; and
wherein the housing of the battery holder comprises an intermediate wall separating laterally adjacent batteries, the intermediate wall comprising an angled portion that accommodates the extension portion of the bottle back wall.

US Pat. No. 10,188,215

LOUNGE ASSEMBLIES FOR SUPPORTING PORTABLE ELECTRONIC DEVICES

Steelcase Inc., Grand Ra...

20. A hood assembly for supporting a portable electronic device having a display screen in a viewable position, the assembly comprising:a hood coupled to a base, the hood including a wall structure that includes an internal surface that forms a substantially downwardly opening cavity, the cavity including a front portion and a rear portion, the cavity opening circumscribed by a lower edge that has a front edge portion adjacent the front portion of the cavity;
a support device supported within the hood and adjacent the front edge portion, the support device configured to receive and support the portable electronic device with the device display screen disposed at an oblique angle to the internal surface such that the display screen is facing and in a line of sight of a user within the hood and blocked from a line of sight from outside of the hood when the hood is in a viewing position; and
a communications device provided in at least one of the hood and the base, and wherein the communications device is configured to communicate with the portable electronic device
wherein the communications device comprises a wireless transceiver coupled within the hood, the transceiver having a sensing field restricted to the space of the cavity.

US Pat. No. 10,188,209

SECURING DEVICE FOR DETACHABLY SECURING A FRONT PANEL ON A DRAWER

Julius Blum GmbH, Hoechs...

1. A securing device for releasably securing a front panel to a drawer, comprising:a furniture fitting to be pre-fitted to the front panel;
a catching device to be connected to the drawer, the catching device configured such that, upon insertion of the furniture fitting, the catching device automatically holds the furniture fitting, and the catching device having a moveable catching element, and
a locking device configured to prevent unintentional release of the furniture fitting from the securing device,
wherein the locking device has a moveable locking element separate from the catching element and configured to bear against the pre-fittable furniture fitting in a locked position, the catching element and the separate locking element being motionally coupled, and
wherein the securing device further comprises an adjusting element fixed to the catching element to couple the motion of the catching element to the motion of the locking element, the adjusting element engaging into an opening in the locking element.

US Pat. No. 10,188,202

BROOM WITH REPLACEABLE BRUSH CARTRIDGE

Bradshaw International, I...

1. A broom with a replaceable brush cartridge comprising:a broom head comprising a top side having a pole receiver for attachment to a pole and a bottom side having a retention skirt;
a track disposed along an inner wall of the retention skirt;
a cartridge receiver formed by the surrounding retention skirt;
a wedge retainer located within the cartridge receiver;
a brush cartridge having an elongated shape and a perimeter groove capable of receiving the track of the broom head;
bristles affixed to the brush cartridge;
a wedge with a live hinge connecting the wedge with the brush cartridge;
the wedge positioned to engage with the wedge retainer of the cartridge receiver when the brush cartridge is installed in the cartridge receiver of the broom head.

US Pat. No. 10,188,191

LIP EXFOLIATING DEVICE

1. A lip exfoliator comprising:an exfoliant comprising an active surface, wherein the active surface is composed of an insoluble dry abrasive material comprising a binding agent that holds in place exfoliating particles;
a bottom section comprising an attachment surface;
a binding mechanism configured to attach the exfoliant to the bottom section, wherein the binding mechanism comprises a solid body that at least partially covers the exfoliant; and
a cap configured to attach to the solid body, wherein the cap covers the active surface when attached to the solid body, and
wherein the attachment surface is adapted to attach to an end of a lip balm by an adhesive.

US Pat. No. 10,188,171

ALIGNMENT SYSTEM FOR A CLEAT AND BASE ASSEMBLY

Speedplay, Inc., San Die...

1. A bicycle cleat assembly configured to be disposed on an underside of a shoe sole, the bicycle cleat assembly comprising:a forward cleat edge and a rearward cleat edge separated at a distance along a longitudinal axis of the bicycle cleat assembly, each of the forward cleat edge and rearward cleat edge having:
a center portion spanning the longitudinal axis, and opposing left and right ends;
opposing left and right sides connecting the forward cleat edge and the rearward cleat edge; and
a pair of guides, each extending from one of the opposing left and right ends of the forward cleat edge to define an expanded landing region for a bicycle pedal;
wherein each of the pair of guides extends forwardly beyond a forwardmost edge of the center portion of the forward cleat edge;
wherein each of the pair of guides further extends outwardly from one of the opposing left and right sides of the bicycle cleat assembly; and
wherein each of the pair of guides extends outwardly at an angle of from 95 degrees to 180 degrees from the forward cleat edge.

US Pat. No. 10,188,148

ELECTRONIC NICOTINE DELIVERY SYSTEM

McNeil AB, Helsingborg (...

1. A system for generating a vapor from a liquid comprising:a) an electric heater having a body comprising at least one sidewall that defines an interior void, at least one inner surface, at least one outer surface, and a plurality of apertures through the at least one sidewall, the electric heater comprising an electrically resistive material contained within a heat diffusing material;
b) an elongate wick having a longitudinal axis, a first end, a second end, and an outer surface, the elongate wick comprising a durable elongate structure having a plurality of liquid-conducting features on the outer surface;wherein at least a portion of the liquid-conducting features of the elongate wick proximate the first end engage at least a portion of the at least one inner surface of the electric heater and at least a portion of the liquid-conducting features of the elongate wick are capable of conducting the liquid from a source proximate the second end of the wick along the outer surface of the elongate wick to the electric heater.

US Pat. No. 10,188,138

SMOKING ARTICLE WITH MANUALLY RELEASABLE ODORANT

Philip Morris USA Inc., ...

1. An article comprising:a tobacco portion;
a filter connected axially aligned with and connected to the tobacco portion;
a tipping paper circumscribing at least a portion of the tobacco portion and at least a portion of the filter;
a first band on at least a portion of the tipping paper, the first band including,
a first layer of a first material over the tipping paper, and
a first plurality of microcapsules between the tipping paper and the first layer of material, the plurality of microcapsules being frangible; and
a second band on a second portion of the tipping paper, the second band including,
a second layer of a second material, and
a second plurality of microcapsules between the tipping paper and the second layer, the second plurality of microcapsules being frangible.

US Pat. No. 10,188,128

AUTOMATIC FROZEN FOOD PRODUCT VENDING MACHINE

The Vollrath Company, L.L...

1. An automatic frozen food product vending machine, comprising:a frozen food product dispensing station for dispensing at least one frozen food product;
a container dispenser for storing a plurality of frozen food product containers and configured to automatically dispense one frozen food product container at a time;
a first movable platform for supporting a dispensed frozen food product container;
a topping dispensing station for dispensing at least one topping;
a second movable platform for supporting the dispensed frozen food product container;
a user input device configured to receive a user selection of a desired frozen food product, a user selection of a desired amount of frozen food product, and a user selection of a desired topping;
processing electronics configured to:
receive the user selection of the desired frozen food product, the user selection of the desired amount of frozen food product, and the user selection of the desired topping;
move the first movable platform below the container dispenser;
cause the container dispenser to dispense one frozen food product container onto the first movable platform;
move the first movable platform and the dispensed frozen food product container below the frozen food product dispensing station;
cause the frozen food product dispensing station to dispense into the frozen food product container a predetermined amount of the selected frozen food product as determined by the user selection of the desired frozen food product and the user selection of the desired amount of frozen food product;
transfer the dispensed frozen food product container from the first movable platform to the second movable platform;
move the second movable platform and the dispensed frozen product container below the topping dispensing station; and
cause the topping dispensing station to dispense into the frozen food product container a predetermined amount of topping as determined by the user selection of the desired topping.

US Pat. No. 10,188,120

MULTIPLE DRAWER SMOKER

LANDMANN USA, Fairburn, ...

1. A smoking apparatus comprising a cabinet having side and rear walls, an upper smoking chamber with a front access door and a lower section having at least two independently operable drawers, one of said drawers disposed above the other and each of said drawers having a front panel with right and left side panels forming an enclosure, a handle attached to each of said front panels, said handles located outside said cabinet, one of said drawers configured to hold a flavoring material and the second drawer configured to hold a liquid, a support surface for each of said drawers secured to said side walls of said lower section, whereby said drawers can be moved into and out of said cabinet using said handles, and a heating element disposed within said cabinet.

US Pat. No. 10,188,107

SELECTIVE INHIBITION OF C4-PEP CARBOXYLASES

HEINRICH HEINE UNIVERSITA...

1. A method of using at least one compound, a salt or solvate thereof as a C4 plant selective herbicide, comprising applying said compound, salt or solvate to a plant, wherein binding of said compound to the malate binding site of aphosphoenolpyruvate carboxylase from a C3 plant is inhibited, and wherein said compound has a structure according toformula (I)
wherein A iswherein R6, R7, R8, R9 and R10 are, independently of each other, selected from the group consisting of H, OH, carboxylic acid, ester, alkyl, alkoxy and halogen, or wherein two residues in ortho position to each other form a heterocyclic ring using —O—CH2—O— or —O—CH2—CH2—O, andB is
wherein R11, R12, R13, R14 and R15 are, independently of each other, selected from the group consisting of H, OH, carboxylic acid, ester, alkyl, alkoxy and halogen, or wherein two residues in ortho position to each other form a heterocyclic ring using —O—CH2—O— or —O—CH2—CH2—O—,
and wherein R1, R2, R3, R4 and R5 are, independently of each other H or an alkyl group,
and wherein integer i is 0 or 1,
and the bond (a) is a single or double bond,
and wherein in case (a) is a double bond, n is 0 and X is O or S, and wherein in case (a) is a single bond n is 1, and X is H or an alkyl group,
and wherein the bond (b) is a single or double bond, and wherein in case (b) is a double bond, m and p are 0, and wherein in case (b) is a single bond m and p are both 1,
and wherein said compound being capable of binding to the malate binding site comprised by a phosphoenolpyruvate carboxylase from a C4 plant, thereby inhibiting said phosphoenolpyruvate carboxylase.

US Pat. No. 10,188,098

EXTREMELY FAST FREEZING, LOW-TEMPERATURE BLAST FREEZER

Reflect Scientific Inc., ...

1. A freezer, comprising:a plurality of shelves in an insulated payload bay;
a plurality of evaporators coupled to the payload bay with a parallel array of coolant tubes in each evaporator, further comprising one or more cryogenic valves coupled to the coolant tubes, wherein one of the cryogenic valves is located at an exhaust port of the freezer;
a rubber pneumatic seal placed between a freezer door and the payload bay;
a pneumatic latch for latching the freezer door and the pneumatic rubber seal are powered by the pressure derived from an exhaust gas;
a pump to force a cryogenic coolant flowing through the evaporators with a pressure of at least 90 psi to supply the coolant at each evaporator with at least 20 gallons per hour of coolant;
a plurality of fans to circulate cooled air in the payload bay;
a room heat exchanger valve controlling a flow of cryogen to a room heat exchanger after the cryogen exits from the evaporators, a room fan that forces air through said room heat exchanger, where the air is cooled and delivered to a room, wherein the fan is controlled by a controller with a room thermocouple as a feedback loop.

US Pat. No. 10,188,091

PORTABLE LIGHT AND INSECT EXTERMINATION DEVICE

alliance sports group, I....

1. A handheld lighting apparatus, comprising:a top housing coupled to a first light source and an electrical grid configured to distribute a quantity of electricity to an object that contacts adjacent portions of the grid, the top housing being slidably mounted to a bottom housing having a cavity therein, the cavity being configured to receive the electrical grid assembly therein,
wherein the first light source emits light ranging from about 400 nm to about 720 nm in a first mode and light ranging from about 315 nm to about 400 nm in a second mode;
an enclosure disposed about the electrical grid assembly configured to permit passage of insects through portions of the enclosure;
a second light source disposed about the bottom housing configured to propagate light in a direction that is parallel to a longitudinal direction of the lighting apparatus;
a power source coupled to the first and second light source and the electric grid; and
a programmable logic control system coupled to a switch and the power source, the control system configured to operate the first light source such that light propagated from one or more LEDs of the first light source ranging from about 315 nm to about 400 nm is pulse width modulated at a rate greater than about 20 KHz while light propagated from one or more LEDs of the first light source ranging from about 400 nm to about 720 nm is not pulse width modulated or is pulse width modulated at a rate below 2 KHz.

US Pat. No. 10,188,088

FISH STRIKE INDICATING APPARATUS, SYSTEM AND METHOD FOR USE WITH AN ICE FISHING TIP-UP

Deep Freeze, LLC, Steven...

1. A fish strike indicating apparatus comprising:an enclosure configured to attach to an ice fishing tip-up flagpole, the enclosure comprising
a cylindrical mounting channel extending longitudinally along a first side of the enclosure, the cylindrical mounting channel adapted to securely receive the flagpole;
a transmitting apparatus disposed inside of the enclosure, wherein the transmitting apparatus is configured to transmit a wireless signal indicative of a fish strike to a mobile device; and
a receiving apparatus disposed inside of the enclosure, wherein the receiving apparatus is configured to receive a wireless signal from the mobile device.

US Pat. No. 10,188,085

SYSTEM AND METHODOLOGY FOR CULTURING COCHINEAL INSECTS ON AN ARTIFICIAL MEDIUM

SciConsult, Inc., Fort W...

1. A self-supporting mass, comprising:an artificial culture medium which contains a plant additive and which has been inoculated with a plurality of insects selected from the group consisting of the genus Dactylopius;
wherein said artificial culture medium further comprises a three-dimensional matrix.

US Pat. No. 10,188,077

HANG-ON NATURAL WATER DRINKING SYSTEM

Ying Yeeh Enterprise Co.,...

1. A hang-on natural water drinking system, provided in form of a hang-on drinking system adapted to effectuate a natural water state, the hang-on drinking system comprising:a holder having a pipe segment;
a water-holding unit for holding drinking water and laterally provided with a connecting segment for drawing water off the water-holding unit, allowing the pipe segment to fit around the connecting segment; and
a drinking unit serving pets and comprising a basic drinking portion, a supporting portion, and a diverting portion, the basic drinking portion having an end extending to form a guide trough, the guide trough abutting against the connecting segment from below to guide water to the basic drinking portion, allowing water to go from an end of a submerged motor to the diverting portion coupled to the basic drinking portion, allowing the water in the diverting portion to flow across at least one blocking region defined at the diverting portion in a manner to enter a turbulent white-water drinking state, wherein the water not only enters the basic drinking portion to serve the pets, but is also driven by the submerged motor coupled to the basic drinking portion to move upward and get introduced into the diverting portion so that the water from the water-holding unit circulates through the drinking unit continuously.

US Pat. No. 10,188,048

SYSTEMS AND METHODS FOR MONITORING MOVEMENT OF DISEASE FIELD

BE SEEN BE SAFE LTD., To...

1. A method for monitoring movement of disease across agricultural areas of interest comprising:displaying, on a map of an application of a first device, at least one virtual zone corresponding to an agricultural geographic area of interest,
the at least one virtual zone defined by at least one geofence,
each virtual zone associated with a level of risk that indicates a likelihood of an outbreak of a disease detrimental to agriculture within the agricultural area of interest,
each virtual zone configured to receive access notification information from each geofence when tracked devices enter an area defined by that geofence,
the access information including the level of risk associated with the tracked devices, and
the level of risk associated with the virtual zone comprising a level of risk associated with the tracked devices that have entered an area defined by the virtual zone within a period of time associated with the disease; and
receiving an alert message associated with a level of risk when the first device is in proximity to a virtual zone associated with that level of risk, the alert message received prior to the first device entering the virtual zone.

US Pat. No. 10,188,031

CUTTER BLADE AND ASSEMBLY FOR A ROTARY CUTTER

Great Plains Manufacturin...

1. A blade assembly for a rotary cutter, said blade assembly comprising:an elongated blade carrier rotatably connected to the rotary cutter;
at least a first cutter blade and a second cutter blade, with one of said cutter blades secured to each opposite side of said blade carrier, wherein rotation of said blade carrier causes a corresponding rotation of said cutter blades;
an elongated base element secured below said blade carrier, wherein said cutter blades are sandwiched between said blade carrier and said base element;
a pair of elongated stop surfaces associated with said first cutter blade, wherein each of said elongated stop surfaces is configured to engage with a length of a side of said first cutter blade to inhibit rotation of said first cutter blade with respect to said blade carrier; and
a pair of elongated stop surfaces associated with said second cutter blade, wherein each of said elongated stop surfaces is configured to engage with a length of a side of said second cutter blade to inhibit rotation of said second cutter blade with respect to said blade carrier.

US Pat. No. 10,188,025

YIELD MONITOR FOR WINDROW-COLLECTED MATERIALS

Clemson University Resear...

1. A yield monitoring system comprising:a windrow collecting implement having an operating width representing the distance between adjacent windrows;
a first sensor carried by the windrow collecting implement and configured to detect a height of a windrow along a travel path at detection points, the windrow disposed below the windrow collecting implement and the first sensor disposed above the windrow;
a second sensor carried by the windrow collecting implement and configured to detect a distance traveled by the windrow collecting implement;
a moisture sensor carried by the windrow collecting implement;
a GPS carried by the windrow collecting implement providing location data of the windrow and windrow collecting implement; and,
a processor configured to process the height of the windrow from the first sensor, the length traveled by the windrow collecting implement from the second sensor, and the operating width to determine a volume of a material contained in the windrow, configured to process the volume of a material contained in the windrow and moisture data to determine a yield map and configured to process location data and the yield map to determine a yield per unit acre.
US Pat. No. 10,188,133

GEL CAPSULE CONTAINING STEROL AND SOLUBILISING AGENT

BASF SE, Ludwigshafen am...

1. A formulation for gel capsules comprising at least 61% by weight sterol ester and at least two solubilizers selected from the group consisting of polysorbates, lecithins, sodium stearoyl-2-lactylates, fatty acid esters of ascorbic acid, fatty acid esters of isoascorbic acid, and sugar esters with fatty acids.
US Pat. No. 10,190,955

SYSTEMS AND METHODS FOR DETERMINING THE EFFECTIVE TOUGHNESS OF A MATERIAL AND FOR IMPLEMENTING MATERIALS POSSESSING IMPROVED EFFECTIVE TOUGHNESS CHARACTERISTICS

California Institute of T...

10. An elastically heterogeneous material comprising:at least a first region comprising a first material characterized by a first elastic modulus;
a plurality of inclusions comprised of a second material characterized by a second elastic modulus;
wherein the inclusions comprise bodies having asymmetric geometries characterized by specific directionality; and
wherein the presence of the inclusions causes the elastically heterogeneous material to have a directionally asymmetric effective toughness such that the effective toughness of the elastically heterogeneous material is greater than it would be if the material was entirely characterized only by the toughness of either the first or second materials alone.
US Pat. No. 10,188,139

ADDITIVES FOR TOBACCO CUT FILLER

Philip Morris USA Inc., ...

1. A method of reducing cytotoxicity and/or mutagenicity in tobacco smoke is provided comprising:applying a solution comprising a mixture of glycerin and a magnesium or calcium salt selected from the group consisting of magnesium nitrate, magnesium chloride, magnesium acetate, magnesium sulfate, calcium nitrate, calcium chloride, calcium acetate and mixtures thereof, onto tobacco cut filler to form a tobacco smoking mixture capable of producing tobacco smoke when burned;
forming a smoking article comprising a wrapper, the tobacco smoking mixture and a filter; and
burning the smoking article to produce tobacco smoke with reduced cytotoxicity and/or mutagenicity;
wherein the glycerin is present in an amount of about 8 to about 13% by weight of the tobacco smoking mixture, and wherein the mixture of glycerin and magnesium or calcium salt is present in an amount effective to reduce the cytotoxicity and/or the mutagenicity of the smoke produced from the tobacco smoking mixture upon burning.