US Pat. No. 10,336,566

FEED TAPE DISPENSER

Shurtech Brands, LLC, Av...

15. A tape dispenser comprising a frame having a top wall and opposed side walls, said top wall connecting the opposed side walls; a tape mount disposed on an interior surface of each of the side walls and being adapted to secure a roll of tape therebetween; a cutter blade disposed on a forward region of the frame and adapted to cut tape from the roll; a bar disposed on the interior surface of one side wall, said bar comprising a hollow semi-cylinder extending between greater than 40% and less than 90% of a distance between said opposed side walls to provide a space between an end of the bar and one side wall.

US Pat. No. 10,336,560

TRANSFER APPARATUS

Azbil Corporation, Tokyo...

1. A transfer apparatus comprising:a first rod-shaped member comprising a magnetic material;
a first terminal member configured to allow insertion of a first end portion of the first rod-shaped member;
a second terminal member configured to allow insertion of a second end portion of the first rod-shaped member;
a second rod-shaped member comprising a magnetic material;
a third terminal member configured to allow insertion of a first end portion of the second rod-shaped member;
a fourth terminal member configured to allow insertion of a second end portion of the second rod-shaped member;
a coupling member configured to couple the second terminal member and the third terminal member; and
an opposite member facing a part of side surfaces of the first and second rod-shaped members and comprising a magnetic material,
wherein the first rod-shaped member and the first terminal member are not fixed, the first rod-shaped member and the second terminal member are fixed to each other, and when the first and second rod-shaped members rotate, the opposite member moves along central axes of the first and second rod-shaped members.

US Pat. No. 10,336,521

FILM FOR PACKAGING AND PACKAGING BAG

TOYOBO CO., LTD., Osaka ...

1. A film for packaging comprising a polyester-based resin film, whereinthe resin film comprises ethylene terephthalate in an amount of more than 50% by mol, based on 100% by mol of the total constituent units of the polyester,
the resin film comprises a polyester-based resin containing a monomer selected from neopentyl glycol, 1,4-cyclohexanedimethanol, and a combination thereof, which monomer is an amorphous component,
the total units derived from a polyhydric alcohol other than ethylene glycol and units derived from a polycarboxylic acid other than terephthalic acid is 13% by mol or more, based on 100% by mol of the total constituent units of the polyester,
the resin film has a density of 1.29 g/cm3 or more and 1.33 g/cm3 or less, and
the resin film has a twist holding angle of 400 degrees or more.

US Pat. No. 10,336,509

SLIDE AND LOCK PACKAGE WITH FILM SEALABLE TRAY

Sonoco Development, Inc.,...

1. A reclosable container comprising:a tray having two lateral sides and comprising a bottom wall, two laterally opposing side walls, a front wall and a rear wall;
the bottom wall having a periphery, the side walls, the front wall and the rear wall each extending upward from the periphery and terminating in a rim;
the bottom wall, the side walls, the front wall and the rear wall defines one or more compartment within the tray for holding a product or products;
the tray further comprising a flat, continuous top wall extending outwardly from the rim and adapted to accept a flexible film in sealing engagement therewith;
the tray further comprising a skirt extending downward from the top wall and a flange extending outwardly from the skirt;
the skirt defining a groove on either lateral side of the tray that extends inwardly from the skirt; and
a lid comprising a cover portion that covers the one or more compartments, two lid side walls extending downward from the cover portion and a lid side flange extending laterally outward from each of the lid side walls;
each lid side wall forming an inwardly extending rib, each rib adapted to slide axially within a corresponding groove in the tray; wherein
the lid is moveable in a sliding fashion relative to the tray between a fully closed position in which the cover portion completely covers the one or more compartments and an open position in which the cover portion does not completely cover the one or more compartments.

US Pat. No. 10,336,503

CONTAINER WITH GRIP STRUCTURE

Graham Packaging Company,...

1. A container comprising:a top portion comprising a finish portion;
a body portion disposed below the top portion; and
a bottom portion disposed below the body portion opposite the top portion;
the body portion comprising:
a front wall,
a rear wall opposite the front wall,
first and second side walls extending between the front wall and the rear wall to define a generally rectangular shape in plan view, the first side wall disposed opposite the second side wall,
opposing grip areas formed in the first and second side walls, the opposing grip areas including a first grip area formed in the first side wall and a second grip area formed in the second side wall,
a first circumferential rib disposed above the opposing grip areas and extending horizontally about an entire outer circumferential perimeter of the body portion,
a second circumferential rib disposed below the opposing grip areas and extending horizontally about the entire outer circumferential perimeter of the body portion,
at least one horizontal body rib disposed between the first and second circumferential ribs and spaced from the opposing grip areas, and
a first vertical strut formed in the first side wall and spaced from the first grip area and a second vertical strut formed in the second side wall and spaced from the second grip area, each of the first and second vertical struts disposed between and spaced from the first and second circumferential ribs and having a length coextensive with a height of the first and the second grip areas respectively, the first and second vertical struts configured to resist radially-inward distortion of the first and second side walls from gripping the opposing grip areas.

US Pat. No. 10,336,495

CONTAINER COMPRISING A SINGLE-PIECE HEAD SECTION

KOCHER-PLASTIK MASCHINENB...

1. A container, comprising:a container body capable of receiving a fluid;
a neck section being connected to said container body and having a dispensing opening at a free end of said neck section capable of dispensing the fluid from said container body;
a head section being removably connected to said neck section by a separating region and releasably sealing said dispensing opening closed; and
a movable sleeve section being coupled to said neck section and being actuatable to remove said head section from said neck section by releasing said separating region to open said dispensing opening, said movable sleeve section being movable from an unactuated state in which said dispensing opening is closed to an actuated state in which said separating region is released and being guided by being at least partially in contact with a guide path that is part of said head section, said guide path being formed on an outside of a ring collar surrounding said head section and extending between said separating region and an annular groove on said head section, said ring collar having an axial extension with a length of said annular groove measured on a smallest diameter size thereof.

US Pat. No. 10,336,484

APPARATUS AND METHOD FOR HELICALLY WRAPPING ARTICLES

OAKBRIDGE INVESTMENTS LIM...

7. A packaging apparatus comprising:a wrapping material applicator for helically wrapping articles;
an inlet conveyor for transporting unwrapped articles to the applicator;
an outlet conveyor for transporting wrapped articles away from the applicator, wherein the outlet conveyor comprises
a first conveyor, and
a second conveyor adjacent to and downstream of the first conveyor; anda controller arranged to selectively vary the linear velocity of the second conveyor relative to the linear velocity of the first conveyor so as to separate, or increase the separation of, collations of one or more articles on the outlet conveyor;wherein the packaging apparatus comprises a cutting member arranged to cut wrapping material extending between the spaced collations of articles, as gaps between the collations pass the cutting member, so as to disconnect the spaced collations of articles.

US Pat. No. 10,336,466

SYSTEM FOR EMULATING NAVIGATION SIGNALS

Garmin International, Inc...

1. A navigation system for emulating navigation signals for an aircraft, said navigation system comprising:a global-positioning system receiver configured to determine a geographic position of the aircraft;
a memory configured to store position data for at least one waypoint;
an emulation system configured to compare the geographic position of the aircraft with the position data of the waypoint and a navigation course to generate a composite navigation signal indicative of a cross track deviation between the aircraft and the navigation course; and
a wireless transmitter coupled with the emulation system, the wireless transmitter configured to wirelessly transmit the composite navigation signal to a course direction indicator having an integral converter unit for decoding the composite navigation signal into a control signal that drives an indicator needle of the course direction indicator.

US Pat. No. 10,336,441

DRONE

LG ELECTRONICS INC., Seo...

1. A drone, comprising:a plurality of propellers configured for creating a lift;
a power driving unit configured for providing a rotation power to each of the plurality of propellers;
a ground sensing unit configured for measuring a distance to a first region of the ground and a shape of the first region;
a controller configured for controlling the power driving unit to differentiate rotation ratios of the plurality of propellers based on the measured distance and shape in response to an input for landing at the first region; and
a variable leg provided to a bottom end of the drone, the variable leg configured to come into a contact with the ground on making the landing and maintain level according to a distance to the ground by withdrawing or inserting the variable leg,
wherein the variable leg comprises:
a first shaft;
a second shaft coupled with a bottom end of the first shaft to be withdrawn or inserted; and
a spring provided between the first shaft and the second shaft.

US Pat. No. 10,336,373

LATERAL ENERGY ABSORPTION SYSTEM

Thunder Power New Energy ...

1. A lateral energy absorption system, comprising:a first carbon structure, comprising:
a first plurality of carbon tubes, wherein
the first plurality of carbon tubes comprise a first end with a first width and a second end with a second width, the first width being greater than the second with,
the first plurality of carbon tubes defines a first taper between the second end and the first end such that between the first and second ends the carbon first structure tapers at an acute angle, wherein the first taper of the carbon tubes facilitates crumpling of the first plurality of carbon tubes during an impact, and
the first plurality of carbon tubes include a first carbon tube having hexagonal shape, a second carbon tube having a circular shape, and a third carbon tube having a rectangular shape;
a first plurality of carbon flanges configured to connect the carbon tubes together, wherein the first plurality of flanges have varying lengths; and
a second plurality of cross supporting members coupling to and extending between the first plurality of carbon tubes in a direction perpendicular or substantially perpendicular to the first plurality of flanges.

US Pat. No. 10,336,361

VEHICLE ACCESSORY CONTROL CIRCUIT

Joyson Safety Systems Acq...

1. A vehicle accessory control circuit, comprising:a processor electrically connected to a power source and a memory, the processor executing computer readable instructions stored on the memory to configure the accessory control circuit and an accessory control output;
at least one capacitive touch assembly coupled to a steering mechanism of the vehicle, the capacitive touch assembly comprising:
a polymer layer;
an electrically conductive conduit at least partially encased within the polymer layer and connected at opposite ends to the power source and the processor such that said conduit transmits a capacitance input data signal to the processor to adjust the accessory control output.

US Pat. No. 10,336,356

WHEELED SHIPPING CART WITH STACKABLE TRAYS

Globe Composite Solutions...

1. An apparatus, comprising:a cart frame;
a plurality of stackable trays supported by said cart frame, each stackable tray comprising:
a tray frame comprising opposed end members, a plurality of longitudinal perimeter members disposed between the opposed end members, and a plurality of upright members nesting with upright members of an adjacent tray; and
a support structure disposed between the opposed end members, the support structure comprising an arcuate upper support surface corresponding to a curved bottom surface of an article to be supported by the support structure, the support structure further comprising a plurality of longitudinal support members each forming an upper surface, the longitudinal support members disposed between the opposed end members in an arced arrangement such that the upper surfaces of the longitudinal support members are in contact with and support an underside of the arcuate upper support surface that supports the curved bottom surface of the article, wherein at least one of the longitudinal support members is positioned above other longitudinal support members to define the arced arrangement; and
a plurality of pins each received through the upright members of the plurality of stackable trays to retain the stackable trays in a stacked configuration.

US Pat. No. 10,336,311

SYSTEM AND METHOD FOR CONTROLLING THE SPEED OF A WORK VEHICLE DURING DOWNHILL OPERATION

CNH Industrial America LL...

1. A method for controlling the speed of a work vehicle during downhill operation, the method comprising:controlling, with a computing device, an operation of at least one of an engine or a transmission of a work vehicle so as to maintain the work vehicle operating at a requested speed;
identifying, with the computing device, an operating condition of the work vehicle that provides an indication that the work vehicle is traveling downhill;
determining, with the computing device, whether at least one pre-condition for downshifting the transmission from a current gear ratio to a downshift gear ratio is satisfied when the operating condition indicates that the work vehicle is currently traveling downhill, the at least one pre-condition including a first pre-condition requiring that the requested speed be less than or equal to an estimated speed for the work vehicle following the downshift;
when it is determined that the at least one pre-condition is satisfied, controlling, with the computing device, the operation of the transmission such that the transmission is downshifted from the current gear ratio to the downshift gear ratio.

US Pat. No. 10,336,306

CONTROL SYSTEM FOR AUTOMATIC PARKING BRAKE OF RAIL VEHICLE

New York Air Brake, LLC, ...

1. A system for controlling an automatic parking brake, comprising:a control valve having an inlet for coupling to a source of brake pipe pressure, an outlet for coupling to a control inlet of the automatic parking brake, and a pilot directly coupled to the source of brake pipe pressure, wherein the control valve is moveable between a first position where the inlet is in communication with the outlet and a second position where the inlet and the outlet are isolated from each other in response to a predetermined amount of brake pipe pressure at the pilot; and
a check valve having a cracking pressure and coupled to the source of brake pipe pressure and the automatic parking brake control inlet, wherein the check valve is in parallel with the control valve.

US Pat. No. 10,336,288

IGNITION DEVICE AND GAS GENERATOR USING SAME

DAICEL CORPORATION, Osak...

1. An ignition device, comprising:an igniter fixed to an igniter collar;
a first cup member filled with a gas generating component therein, the first cup member having a first circumferential wall and a first bottom surface closing one end of the first circumferential wall; and
a second cup member having a second circumferential wall opposing the first circumferential wall and a second bottom surface closing one end of the second circumferential wall and opposing the first bottom surface,
the first cup member covering the igniter collar and enclosing an ignition portion of the igniter,
the second cup member covering the igniter collar and enclosing the first cup member,
a continuous gap, as a heat insulating layer, defined by an outer surface of the first circumferential wall and the first bottom surface of the first cup member and an inner surface of the second circumferential wall and the second bottom surface of the second cup member, the continuous gap being an air layer that contains no gas generating component therein,
the first cup member having a first opening, and the second cup member having a second opening, and
at least one of the first opening and the second opening being closed before actuation and being opened only when gas is generated from the gas generating component.

US Pat. No. 10,336,282

SELF-CONFORMING REARSEAT AIR BAG

TRW VEHICLE SAFETY SYSTEM...

3. An apparatus for helping to protect a rear seat occupant of a vehicle, the apparatus comprising an airbag having a stored condition in a housing mounted to or within a seatback of a vehicle seat positioned in front of the rear seat occupant, the airbag comprising one or more panels of material interconnected to define an inflatable volume and having a substantially U-shaped configuration when viewed from the side, wherein the airbag includes a first portion that forms one leg of the U-shaped airbag, a second portion that forms another leg of the U-shaped airbag, and a third portion that interconnects the first and second portions, the airbag being configured so that when inflated its U-shaped configuration is inverted such that the third portion forms a top portion of the airbag.

US Pat. No. 10,336,256

REDUCTION OF LED HEADLIGHT FLICKERING IN ELECTRONIC MIRROR APPLICATIONS

Ambarella, Inc., Santa C...

1. An apparatus comprising:a sensor configured to generate a first video signal; and
a processor configured to (A) search for a flickering effect in a frame of said first video signal, (B) determine a location and a region of pixels to modify within said frame in response to said flickering effect, (C) determine a modification based on said flickering effect in said frame, (D) perform said modification of said region of pixels in said first video signal by determining average values of pixels based on said location of said region of pixels over consecutive frames of said first video signal and (E) generate a second video signal in response to (i) said modification of said region of pixels and (ii) said first video signal, wherein said second video signal masks said flickering effect by modifying pixels of said region of said second video signal when viewing said second video signal on a display.

US Pat. No. 10,336,249

SYSTEM AND METHOD FOR PEDESTRIAN ALERT

2236008 Ontario Inc., Wa...

1. A method for pedestrian alert comprising:deriving a pedestrian path representing a projected path for a pedestrian;
deriving a vehicle path representing a projected path for a vehicle;
determining an intersection of the pedestrian path and the vehicle path;
determining an environmental noise level detected by an external microphone;
determining an alert characteristic responsive to the determined intersection; and
emitting an alert signal from the vehicle responsive to the determined alert characteristic,
wherein the determined alert characteristic is adjusted responsive to the environmental noise level; and
wherein the emitted alert signal draws the attention of the pedestrian to the presence of the motor vehicle to mitigate a likelihood of a collision between the vehicle and the pedestrian.

US Pat. No. 10,336,198

CHARGE CABLE LOCK DEVICE

KABUSHIKI KAISHA TOKAI RI...

1. A charge cable lock device for use with an inlet that includes an inlet housing, wherein a charge cable including a rocking arm with a hooking portion is connected in a removable manner to the inlet, the charge cable lock device comprising:a lock member movable to a lock position and an unlock position, wherein the lock member is configured to contact the rocking arm to restrict disengagement of the hooking portion of the rocking arm from the inlet when the lock member is located at the lock position;
a lock housing that supports the lock member; and
a fixing pin configured to be inserted into the lock housing and the inlet housing and fix the lock housing to the inlet traversing the lock housing and the inlet housing,
wherein the fixing pin includes a metal one-piece component including
distal linear portions that are parallel to each other, and
a bridge that connects the distal linear portions.

US Pat. No. 10,336,170

VARIABLE BELT MOLDING STRUCTURE FOR VEHICLE DOOR

Hyundai Motor Company, S...

1. A variable belt molding structure for a vehicle door, the variable belt molding structure comprising:a skin disposed in a fixed quarter window and a rear door window formed in a rear door of a vehicle to have a width that is varied in a longitudinal direction thereof;
a carrier portion internally coupled to the skin to maintain air-tightness by being in contact with a window glass of the rear door window;
a clip mounted to be internally coupled to the carrier portion and mounted in a door panel of the rear door; and
a first mounting clip coupled to a fixed quarter window bracket attached to the fixed quarter window,
wherein the skin includes:
a first skin extension configured to extend downward in a height direction of the vehicle; and
a second skin extension integrally formed with the first skin extension to extend in a horizontal direction thereof or a horizontal and upward direction thereof, and
wherein a first flange is formed in the second skin extension of the skin to protrude downward in the height direction of the vehicle, and the first mounting clip is disposed in the first flange.

US Pat. No. 10,336,167

APPARATUS FOR PREVENTING INFLOW OF DUST IN REAR RAIL OF SUNROOF

Hyundai Motor Company, S...

1. An apparatus for preventing an inflow of dust in a rear rail of a sunroof, the apparatus comprising:the rear rail of the sunroof which is disposed in a longitudinal direction thereof;
a tilt lever which has a first end portion coupled to a moving glass and a second end portion disposed on the rear rail, and slides along a trajectory of the rear rail;
a tilt lever shoe which is disposed at the second end portion of the tilt lever, and configured to be fastened by being fitted with the rear rail; and
at least one guide rail which is disposed to protrude from the rear rail in a width direction of a vehicle,
wherein an internal surface of the tilt lever shoe is disposed to contact with at least one of upper and lower surfaces of the at least one guide rail,
wherein at least two layers of the at least one guide rail are surrounded by the tilt lever shoe so as to prevent a dust from flowing into the rear rail, and
wherein the at least two layers include:
an upper layer, wherein at least a surface of the upper layer is spaced with a gap from an inner upper of the tilt lever shoe; and
a lower layer, wherein upper, lower and left and right surfaces of the lower layer are in contact with the internal surface of the tilt lever shoe.

US Pat. No. 10,336,159

REFRIGERATION

DEARMAN ENGINE COMPANY LT...

1. A system comprising:a cryogenic engine system comprising:
an output shaft;
a first expander utilizing a working fluid and heat exchange fluid within the first expander;
a circuit comprising an introducer, the introducer providing said heat exchange fluid into the first expander and wherein the first expander is configured to cause expansion of said working fluid within the first expander such as to produce shaft power;
a refrigeration system, including a heat exchange system wherein:
the cryogenic engine system and the refrigeration system are thermally coupled with each other via the heat exchange system such that the working fluid or heat exchange fluid in the cryogenic engine system acts as a heat sink for removing heat from the refrigeration system and heat generated by the refrigeration system is used to expand the working fluid in the cryogenic engine system;
a refrigeration compartment thermally connected to the heat exchange system;
wherein the cryogenic engine system is a direct and an indirect heat sink for removing heat from the refrigeration compartment; and
wherein the heat exchange system comprises:
a first heat transfer member in direct thermal contact with the working fluid from the cryogenic engine system and in direct thermal contact with the refrigeration compartment;
a second heat transfer member in direct thermal contact with expanded working fluid and the heat exchange fluid of the cryogenic engine system;
a third heat transfer member in direct thermal contact with an interior of the refrigeration compartment; and
an intermediate heat transfer fluid circulation system in thermal contact with both the second heat transfer member and the third heat transfer member.

US Pat. No. 10,336,108

CREDENTIAL PRODUCTION DEVICE HAVING A MOVABLE PROCESSING ASSEMBLY

ASSA ABLOY AB, Stockholm...

1. A credential production device comprising:processing path;
a transport mechanism configured to feed individual substrates along the processing path;
a processing assembly comprising:
a supply spool support;
a take-up spool support;
a plurality of ribbon supports that define a ribbon path; and
one of a print head and a transfer roller; and
at least one assembly guide configured to guide linear movement of the processing assembly substantially perpendicularly to the processing path between an operating position and a loading position relative to the processing path.

US Pat. No. 10,336,048

FILM LAMINATOR FOR CELL PHONES

Alpha Comm Enterprises, L...

1. An apparatus for applying protective film to the screen of a portable electronic device having a defined shape, comprising:a fixing plate shaped to receive said portable electronic device, said fixing plate having a horizontal top surface and an opening in said horizontal top surface accommodating the defined shape of said portable electronic device;
a protective film assembly comprising a first outer film, a primary protective film layer, and a second outer film; and
a hinge bonded to a portion of said protective film assembly and to said horizontal top surface of said fixing plate,
wherein said first outer film is configured to be completely removed from said primary protective film layer, using a separating strip, prior to adhering said primary protective film layer to the screen of said portable electronic device.

US Pat. No. 10,336,035

POLYURETHANE BASED RIGID FLOORING LAMINATE

SCHNELLER LLC, Kent, OH ...

1. A laminate structure comprising:a backing layer comprising a fiber reinforcement with a thermoset or thermoplastic polymer resin matrix;
a base layer comprising an alloy layer made of polyurethane in combination with a terpolymer comprising polyamide, polyester and polyether or a combination thereof; and
an adhesive layer disposed on a first surface of the base layer between the backing layer and the base layer; and
a cap layer comprising polyurethane, wherein the peel resistance between the combination of the cap layer and base layer and the backing layer is at least about 103 Newtons (N) per 25 millimeters after aging for at least 500 hours, wherein the laminate meets the toxicity flaming and non-flaming test protocols pursuant to AITM 2.0007 with respect to HCN, CO, NO2, SO2/H2S, HF, and HCl limits, said limits being less than 150, 1000, 100, 100, 100, and 150 respectively as measured by specific optical density, in addition to Federal Aviation Regulation 25.853 MD with regard to the parameters of vertical burn, drip time and char of the laminate, said limits being less than 15 seconds, 5 seconds and 203 mm respectively, and further having a tear strength of greater than 50 Newtons according to ISO 4674, method A, and an areal density of between 1800 and 2100 grams per square meter.

US Pat. No. 10,336,025

COMPOUND LENS FOR USE WITH ILLUMINATION SOURCES IN OPTICAL SYSTEMS

Lumenflow Corp., Wyoming...

1. A compound lens comprising:a first lens element;
a second lens element in alignment with the first lens element along a common optical axis, wherein the first and second lens elements are integrally joined to each other, wherein the first and second lens elements are co-molded from a silicone resin, and wherein the first and second lens elements are optically coupled to each other to reduce the optical path difference of center ray bundles and sagittal ray bundles propagating through the compound lens;
a third lens element integrally joined to the second lens element, the third lens element being a bi-concave frusto-conical lens, the bi-concave frusto-conical lens separating the center ray bundle from the sagittal ray bundle; and
a fourth lens element integrally joined to the third lens element, the fourth lens element being a bi-convex aspheric lens, wherein the third and fourth lens elements are in alignment with the first and second lens elements along the common optical axis.

US Pat. No. 10,335,945

SUBSTRATE TRANSPORT APPARTATUS WITH MULTIPLE MOVABLE ARMS UTILIZING A MECHANICAL SWITCH MECHANISM

Brooks Automation, Inc., ...

1. A substrate transport apparatus comprising:a drive section having coaxial drive shafts and at least a first and a second independently controllable motor coupled to a respective first and second drive shaft of the coaxial drive shafts;
a first articulated arm having a first arm link and a first end effector connected to the first arm link for holding a substrate thereon;
a second articulated arm having a second arm link and a second end effector connected to the second arm link for holding a substrate thereon; and
each of the first and second arm links being rotatably joined by the coaxial drive shafts to rotors of both of the first and second independently controllable motors such that simultaneous movement of the first and second independently controllable motors effects extension of an extension arm of the first and second articulated arms and rotation of a rotating retracted arm of the first and second articulated arms wherein the first articulated arm is respectively the extension arm while the second articulated arm is the rotating retracted arm and is the rotating retracted arm while the second articulated arm is the extension arm, so that each of the first arm link supporting the first end effector respectively become extension arm links as each of the second arm link supporting the second end effector respectively become rotating retracted arm links and so that each of the second arm link supporting the second end effector respectively become extension arm links as each of the first arm link supporting the first end effector respectively become rotating retracted arm links that are rotated in a substantially retracted configuration so that each of the rotating retracted arm links of the rotating retracted arm being rotated in the substantially retracted configuration, is maintained in a substantially constant position, with respect to each other rotating retracted arm link of the rotating retracted arm being rotated in the substantially retracted configuration, by a common drive shaft, of the coaxial drive shafts, rotating in a common direction relative to and substantially simultaneously with the rotating retracted arm effecting extension of the extension arm with rotation of the rotating retracted arm being rotated in the substantially retracted configuration.

US Pat. No. 10,335,880

RACKS FOR HIGH-TEMPERATURE METAL PROCESSING

H.C. STARCK INC., Newton...

1. An apparatus for receiving and supporting one or more components during processing thereof at a process temperature greater than approximately 1000° C., the apparatus comprising:a first shelf (i) comprising a first refractory metal having a melting point greater than the process temperature and (ii) defining therethrough a plurality of apertures, each aperture being threaded through at least a portion of its thickness;
a plurality of first support posts, each first support post (i) comprising a second refractory metal having a melting point greater than the process temperature, (ii) having a threaded lower end for engagement with a threaded aperture of the first shelf, and (iii) defining a support collar proximate an upper end opposite the threaded lower end, a lateral dimension of the first support post above the support collar being smaller than a lateral dimension of the first support post below the support collar;
a second shelf (i) comprising a third refractory metal having a melting point greater than the process temperature and (ii) defining therethrough a plurality of apertures, each aperture of the second shelf being configured to receive the upper end of one of the first support posts such that a portion of the second shelf proximate each aperture thereof rests upon the support collar of the first support post received in the aperture,
a third shelf (i) comprising a fourth refractory metal having a melting point greater than the process temperature and (ii) defining therethrough a plurality of apertures; and
a plurality of second support posts, each second support post (i) comprising a fifth refractory metal having a melting point greater than the process temperature, (ii) having a threaded lower end for engagement with a threaded aperture, (iii) defining a support collar proximate an upper end opposite the threaded lower end, a lateral dimension of each second support post above the support collar being smaller than a lateral dimension of each second support post below the support collar, and (iv) defining a dowel pin mount through the upper end thereof above the support collar,
wherein (A) the upper end of each second support post is receivable within an aperture of the third shelf such that (i) a portion of the third shelf proximate each aperture thereof rests upon the support collar of the second support post received in the aperture, and (ii) the dowel pin mount of each second support post is disposed above a top surface of the third shelf, (B) each of the apertures of the second shelf is threaded through at least a portion of its thickness, and (C) the threaded lower end of each second support post is receivable within one of the threaded apertures in the second shelf.

US Pat. No. 10,335,874

RECIPROCATING TOOL

KOKI HOLDINGS CO., LTD., ...

1. A reciprocating tool for moving a tip tool in a reciprocating direction to achieve a cutting action, comprising:a housing accommodating:
a motor;
a power transmission member, driven by the motor, revolving around a rotation axis crossing the reciprocating direction;
a plunger extending in the reciprocating direction, one end of the plunger holding the tip tool;
a connector coupling the power transmission member to another end of the plunger and converting a revolving motion of the power transmission member into a reciprocating motion of the plunger holding the tip tool in the reciprocating direction, the connector having a support member protruding from the connector in a direction perpendicular to the reciprocating direction;
a guide member fixed to the housing and extending along the reciprocating direction, wherein
the support member of the connector slidably and rockably engages with the guide member so that the guide member guides a movement of the connector to convert the revolving motion of the power transmission member into the reciprocating motion of the plunger, and
the connector supports the plunger to allow the plunger to move together with the connector.

US Pat. No. 10,335,824

GLUE APPLICATION ROLLER FOR USE IN A GLUING ASSEMBLY EQUIPPED WITH AT LEAST ONE SCOOPING ROLLER

MUELLER MARTINI HOLDING A...

1. A glue application roller for use in a gluing assembly equipped with at least one scooping roller, the glue application roller comprising:a glue roller body that is provided with a central hole to receive a drive shaft, the glue roller body having at least two parts including:
a base that is operatively connected to the drive shaft by a non-positive fit, and
an outer ring that is configured with at least one cavity, the base and the outer ring being coupled to each other by at least one force-locking connection,
wherein, on at least one side of the glue roller body, there are flow-conduits that ensure that compressed air and/or another gaseous or liquid medium is fed into or discharged from the cavity so as to effectuate a change in a circumferential contour of the cavity.

US Pat. No. 10,335,720

OPTIMIZATION OF VACUUM SYSTEM AND METHODS FOR DRYING DRILL CUTTINGS

FP Marangoni Inc., Calga...

1. A method of retro-fitting a shaker to include an air vacuum system, the air vacuum system for improving the separation of drilling fluid and drill cuttings on the shaker, the method comprising the steps of:a. installing a vacuum frame and manifold over screen support rails of a shaker;
b. installing a screen on the vacuum frame and manifold such that the vacuum frame and manifold mates with the underside of the screen; and
c. securing each of the support rails, vacuum screen and manifold and screen together for enabling a vacuum pressure to be applied to the underside of the screen;
wherein the shaker has at least two pairs of support rails and the vacuum frame and manifold is installed on a downstream pair of support rails, leaving at least one upstream pair of support rails without a vacuum frame and manifold.

US Pat. No. 10,335,706

COMBINED LIFTING BARN FENCING EQUIPMENT

Zhejiang Dafeng Industry ...

1. A combined lifting barn fencing equipment, comprising:a barn (1) movably mounted in a first annular groove in the periphery of a stage,
a lifting mechanism (4) that drives the barn (1) to lift up and down,
a fence (2) movably mounted in a second annular groove (11) of the barn (1), and
a hoisting mechanism that drives the fence (2) to lift up and down,
wherein the lifting mechanism is mounted at the bottom of the first annular groove, the hoisting mechanism (3) is mounted at the top of a gate above the stage, the barn (1) is mounted to a bedplate (6); the barn (1) descends to the first annular groove or rises to above of the stage driven by the lifting mechanism (4), when the barn (1) descends to the first annular groove, the upper surface of the bedplate (6) is flush with a stage surface; when not connected with the hoisting mechanism (3) for lifting, the fence (2) is retained inside the second annular groove (11), when connected with the hoisting mechanism (3) for lifting, the fence (2) is hoisted to the above of the stage.

US Pat. No. 10,335,637

SYSTEM AND METHOD FOR IDENTIFYING AND INTERPRETING REPETITIVE MOTIONS

Focus Ventures, Inc., Sa...

1. A computer based method for interpreting repetitive movements performed by a user of a motion tracking device as part of updating a physical therapy treatment, the method comprising:receiving motion data from the motion tracking device, the motion data representing motions performed by the user of the motion tracking device associated with a repetitive movement associated with the physical therapy treatment;
determining, by the computer, based on the motion data and the repetitive movement, a form with which the user performs the repetitive movement having the steps of:
identifying, by the computer, repetitive features in one or more signals of the motion data;
comparing, by the computer, the repetitive features with correct movement data associated with the repetitive movement; and
determining, by the computer, based on the comparison, the form with which the user is performing the repetitive movement including the steps of:
identifying, by the computer, repetitive features in one or more signals of the motion data;
comparing, by the computer, the repetitive features with correct movement data associated with the repetitive movement; and
determining, by the computer, based on the comparison, the form with which the user is performing the repetitive movement;
generating, by the computer, based on the determined form with which the user performs the repetitive motion, feedback, the feedback representing the form with which the user is performing the repetitive movement;
receiving an updated physical therapy treatment based upon the determined form.

US Pat. No. 10,335,632

TREADMILL INCLUDING A DECK LOCKING MECHANISM

Nautilus, Inc., Vancouve...

1. A treadmill comprising:a frame;
a deck assembly including a front end portion pivotally connected to the frame, the deck assembly positionable in an operating position and a storage position;
a first tube connected to one of the frame or the deck assembly, the first tube defining an aperture and a slot spaced apart from each other along a length of the first tube, wherein the slot extends lengthwise along the length of the first tube;
a second tube connected to the other of the frame or the deck assembly and slidably connected to the first tube; and
a lock mechanism operative to lock the deck assembly in the operating position and the storage position, the lock mechanism comprising:
a pin operatively connected to the second tube and engageable with the aperture and the slot of the first tube; wherein:
engagement of the pin with the aperture locks the deck assembly in the storage position; and
engagement of the pin with the slot locks the deck assembly in the operating position while allowing incline adjustment of the front end portion of the deck assembly relative to the frame during operation of the treadmill, wherein the slot is dimensioned to receive at least a portion of the pin and allow the pin to slide within the slot.

US Pat. No. 10,335,619

FIREFIGHTER MULTIFUNCTION LADDER AND ESCAPE BELT

Fire Innovations LLC, Pe...

1. A multifunction escape and ladder belt, comprising:a front buckle having a first buckle member and a second buckle member, coupling apparatus to connect said first member to said second member, each of said first and second members having a slot through which a fabric side strap may be passed;
left and right adjustment buckles, each configured with rigid bars defining front, middle, and rear adjustment slots through which strap fabric portions may be passed;
left and right side straps, said left side strap connected at a first end to said first buckle member and having a second end threaded through said middle adjustment slot of said left adjustment buckle, then through said front adjustment slot of said left adjustment buckle, and said right side strap connected at a first end to said second buckle member and having a second end threaded through said middle adjustment slot of said right adjustment buckle, then through said front adjustment slot of said right adjustment buckle; and
a rear strap having an outward facing continuous back portion, a first end threaded through said rear slot of said left adjustment buckle and extending to a medial portion of said rear strap, a second end threaded through said rear slot of said right adjustment buckle and extending to said medial portion of said rear strap so as to put said first end and said second end in an overlapping configuration, and first and second energy-release double-loop portions, one of each formed in said rear strap proximate each of said left and right adjustment buckles forming a double-looped overlapping portion secured by stitching;
wherein said stitching forms a stitched strap connection having a predetermined minimum breaking strength.

US Pat. No. 10,335,611

GANTRY IMAGE GUIDED RADIOTHERAPY SYSTEM AND RELATED TREATMENT DELIVERY METHODS

ACCURAY INCORPORATED, Su...

1. A method, comprising:receiving a pre-acquired image data set of a target acquired in a reference frame generally independent of a reference frame of an image guided radiation treatment (IGRT) apparatus;
during a patient setup interval, positioning the target into an initial treatment position relative to the IGRT apparatus, the initial treatment position being along an axis of rotation of a rotatable gantry structure of the IGRT apparatus;
rotating the rotatable gantry structure through a range of gantry angles;
subsequent to the patient setup interval, operating a first x-ray cone beam imaging source and a first imaging detector to acquire a first population of x-ray cone beam projection images of the target for a respective first population of gantry angles and acquisition times;
processing the first population of x-ray cone beam projection images to compute therefrom a time sequence of sliding-window tomographic image volumes characterized in that each subsequent member of the time sequence is computed using at least one same x-ray cone beam projection image as used in computing at least one previous member of the time sequence, wherein the sliding-window tomographic image volume comprises a tomosynthesis reconstructed image volume; and
operating the IGRT apparatus to deliver treatment radiation to the target based at least in part on a comparison between at least one of the time sequence of sliding-window tomographic image volumes and the pre-acquired image data set.

US Pat. No. 10,335,577

AUGMENTED DELIVERY CATHETER AND METHOD

Nfinium Vascular Technolo...

1. A catheter apparatus for placement within a blood vessel to at least partially occlude the blood vessel, the catheter apparatus comprising:an outer sheath having a distal end;
an inner sheath having a distal end, the inner sheath being axially translatable and fitting within the outer sheath; and
an expansile anchor mechanism deployable between collapsed and expanded configurations by axially translating the inner and other sheaths relative to one another,
wherein the expansile anchor mechanism comprises a distal end coupled to the distal end of the outer sheath and a proximal end coupled to the distal end of the inner sheath,
wherein the expansile anchor mechanism comprises a fluid permeable tubular mesh braid and an impermeable elastomeric membrane covering at least a portion of the tubular mesh braid to at least partially obstruct blood flow in the blood vessel when the expansile anchor mechanism is in the expanded configuration within the blood vessel, and
wherein the impermeable elastomeric membrane allows antegrade blood flow beyond a distal tip of the distal end of the outer sheath while limiting the blood flow to cause pressure in the blood vessel distal to the distal tip to be less than pressure in the blood vessel proximal to the distal tip when the expansile anchor mechanism is in the expanded configuration within the blood vessel.

US Pat. No. 10,335,571

BREATHABLE GAS INLET CONTROL DEVICE FOR RESPIRATORY TREATMENT APPARATUS

ResMed Paris SAS, (FR)

1. A respiratory treatment apparatus configured to provide a flow of breathable gas to a patient in successive respiratory cycles, each cycle including an inspiration phase and an expiration phase, comprising:a gas inlet having a variable aperture that is adjustable between a range of positions from a closed position and to fully open;
a gas outlet; and
a flow generator adapted to provide a supply of pressurized breathable gas from the gas inlet and to the gas outlet, the gas inlet conducting the supply of pressurized breathable gas to the flow generator; and
a controller to control the pressure generated by the flow generator,
wherein the variable aperture is configured to, during the inspiration phase of each respiratory cycle, vary proportionally in opening size as a function of an induced level of flow of breathable gas provided adjacent to the gas outlet, said induced level of flow generated by the patient.

US Pat. No. 10,335,541

PUMP CASSETTES WITH FLOW STOP AND INFUSION PUMP SYSTEMS

CareFusion 2200, Inc., S...

1. A pump cassette comprising: a rigid body comprising two opposing edge sections, an inlet port, an outlet port, and a controllable fluid pathway extending from the inlet port to the outlet port; a slider coupled to the two opposing edge sections and longitudinally articulable along the two opposing edge sections with respect to the rigid body; and a flow stop valve operably coupled to the controllable fluid pathway, wherein the flow stop valve is disposed on the rigid body such that longitudinal articulation of the slider along the two opposing edge sections causes a portion of the slider to actuate the flow stop valve, wherein the flow stop valve is configured to occlude fluid flow through the controllable fluid pathway when the slider is in a first position, and to allow fluid flow through the controllable fluid pathway when the slider is in a second position, wherein the flow stop valve comprises a striker portion coupled to a membrane portion, wherein the portion of the slider is configured to depress the striker portion to urge the membrane portion to occlude fluid flow through the controllable fluid pathway, wherein the striker portion comprises a piece attached to the membrane portion, wherein the portion of the slider is configured to contact the piece to depress the piece when the slider is in the first position, and wherein the piece is configured to align under a recess of the slider such that the slider does not contact the piece when the slider is in the second position.

US Pat. No. 10,335,537

INTEGRATED STRONTIUM-RUBIDIUM RADIOISOTOPE INFUSION SYSTEMS

Bracco Diagnostics Inc., ...

1. An infusion system on-board a cart comprising:a first shielding compartment having a first opening through which a strontium-rubidium radioisotope generator can be inserted into and removed from the first shielding compartment;
a first door configured to provide access to the first shielding compartment and to close over the first opening;
a second shielding compartment having a second opening through which a waste bottle can be inserted into and removed from the second shielding compartment;
a radioactivity detector positioned to measure radioactivity of a rubidium radioactive eluate flowing through an eluate tubing line in fluid communication with an outlet tubing port of the strontium-rubidium radioisotope generator;
a computer configured to receive an input from a user for controlling operation of the infusion system, wherein the computer is in electronic communication with a screen display;
a shielded detector compartment configured to receive the radioactivity detector; and
wherein the computer of the infusion system is configured to:
pump saline from a saline reservoir into the strontium-rubidium radioisotope generator through an inlet tubing port of the strontium-rubidium radioisotope generator thereby generating the rubidium radioactive eluate that is discharged through the outlet tubing port,
fill an eluate reservoir in a shielded well with a test sample to a predetermined volume,
receive a strontium breakthrough test result of the test sample filled into the eluate reservoir in the shielded well, wherein the strontium breakthrough test result of the test sample filled into the eluate reservoir in the shielded well is determined with a second radioactivity detector;
not allow a patient infusion if the strontium breakthrough test result is greater than or equal to an allowed limit;
measure a radioactivity of the test sample with the radioactivity detector while the test sample is flowing through the eluate tubing line to the eluate reservoir in the shielded well;
measure a calibration radioactivity of the test sample with the second radioactivity detector while the test sample remains in the eluate reservoir;
compare the radioactivity of the test sample measured by the radioactivity detector with the calibration radioactivity of the test sample measured by the second radioactivity detector;
track a volume of saline in the saline reservoir;
not allow the patient infusion if the volume of saline in the saline reservoir is below a predetermined saline threshold;
track a volume of waste in the waste bottle;
not allow the patient infusion if the volume of waste in the waste bottle is above a predetermined waste threshold.

US Pat. No. 10,335,426

N-ACETYL MANNOSAMMINE AS A THERAPEUTIC AGENT

THE UNITED STATES OF AMER...

1. A method of treating a condition or disease in a mammal in need thereof comprising selecting a subject with the condition or disease, and administering to the subject an effective amount of N-acetyl mannosamine or a derivative thereof, to the mammal, wherein the derivative consists of Formula I.wherein R1, R3, R4, or R5 is hydrogen, lower alkanoyl, carboxylate or lower alkyl; R2 is lower alkyl, lower alkanoylalkyl, lower alkyl alkanoyloxy; and the condition or disease is diabetic nephropathy.

US Pat. No. 10,335,406

OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE

Elysium Therapeutics, Inc...

1. A composition comprising a macromolecule of Formula (I):
and a therapeutically-effective amount of a macromolecule of Formula (II):

or pharmaceutically acceptable salts thereof, wherein:
PD is a gastrointestinal enzyme-labile opioid agonist prodrug and the gastrointestinal enzyme-labile opioid agonist prodrug is:

wherein:
Y is H or OH;
AA is a natural or unnatural amino acid side chain that is recognized by the gastrointestinal enzyme; and
R is independently hydrogen, methyl, ethyl, substituted alkyl, acyl, a natural or unnatural amino acid, or a polypeptide comprising up to 10 natural and/or unnatural amino acids;
I is a gastrointestinal enzyme inhibitor and the gastrointestinal enzyme inhibitor is:

X2 is independently at each occurrence absent or
that joins I to a polymer P2 wherein: k and m are independently at each occurrence an integer from 0 to 10;X1 is independently at each occurrence absent or an ether, an ester, a thioester, an amide, an amine, a carbamate, a carbonate, a thioether, or a urea, wherein the nitrogen atom of the amide, amine, or carbamate, is substituted or unsubstituted and the nitrogen atoms of the urea are each independently substituted or unsubstituted, that joins PD to a polymer P1;
each P1 and P2 is independently a polyalkylene glycol; and
n is independently an integer from 1 to 2.

US Pat. No. 10,335,394

PROCESSES FOR PREPARING DOLUTEGRAVIR AND CABOTEGRAVIR AND ANALOGUES THEREOF

Lek Pharmaceuticals d.d.,...

1. A process for preparing a compound of formula (I) or a salt thereof
wherein
A represents CH2 or CH2—CH2,
R represents H, C1-C4 alkyl or unsubstituted or substituted phenyl,
X represents O, S, or N—R5, wherein R5 is H or C1-C4 alkyl,
Z represents hydroxy, C1-C4 alkoxy, phenoxy, benzoxy, —NH—Ar or—NH—CH2—Ar,
wherein Ar represents unsubstituted or substituted phenyl, and
* represents a chirality center, which is of (R) or (S) configuration,
the process comprising the steps of
(a) providing a compound of formula (II) or a salt thereof,

wherein A, R, X, Z, and * have the same meaning as above and
Y represents Cl or O—Ra,
wherein Ra represents C1-C4 alkyl or benzyl,
and
(b) carrying out a chemical transformation to obtain the compound of formula (I) and/or a salt thereof,
wherein the transformation is carried out in the presence of a hydroxide and methanol and/or ethanol.

US Pat. No. 10,335,393

NUCLEAR TRANSPORT MODULATORS AND USES THEREOF

Biogen MA Inc., Cambridg...

1. A compound of formula I:
or a pharmaceutically acceptable salt thereof, wherein:
R1 is selected from hydrogen and C1-C4 alkyl;
R2 is selected from O; and
R3 is —C1-C6 alkyl, wherein R3 is optionally and independently substituted with one or more substituents selected from the group consisting of —OH, —SH, nitro, halogen, amino, cyano, C1-C12 alkyl, C2-C12 alkenyl or C2-C12 alkynyl group, C1-C12 alkoxy, C1-C12 haloalkyl, C1-C12 haloalkoxy and C1-C12 alkyl sulfanyl.

US Pat. No. 10,335,379

ORAL DOSAGE FORMS OF KETAMINE

Develco Pharma Schweiz AG...

1. An oral dosage form comprising ketamine or a pharmaceutically acceptable salt or solvate thereof,wherein the dosage form provides an in vitro release of ketamine, when measured according to the USP Basket Method I in 0.1M HCl at 37° C. at 100 rpm, of 0 to 40% after 2 hours, of 10 to 70% after 4 hours, of 30 to 85% after 6 hours and of 45 to 100% after 8 hours,
wherein the dosage form provides an in vitro release of ketamine, when measured according to the USP 1 Basket Method in 0.1M HCl at 100 rpm, after one hour at 37° C., in an aqueous solution containing 20% by volume of ethanol, in a ratio of less than 2:1 relative to the amount of ketamine released, so measured, after one hour at 37° C. in an ethanol-free aqueous solution,
wherein the dosage form is a multi-particulate controlled release tablet,
wherein the tablet comprises pellets each containing
i) a core comprising
1 to 30 wt. % inert beads,
5 to 400 mg and 1 to 40 wt. % ketamine hydrochloride,
0.01 to 10 wt. % binder, and
0 to 10 wt. % glidant, and
ii) a release control layer comprising
1 to 40 wt. % of a release control substance coated upon the core, wherein the release control substance is a water insoluble polymer,
0.01 to 10 wt % pore builder,
0.01 to 10 wt. % plasticizer, and
0 to 15 wt. % glidant, and
wherein the pellets are contained in an external phase comprising
carboxymethyl cellulose, optionally in the form of a salt, as a pharmaceutically acceptable excipient,
20 to 85 wt. % filler,
0 to 3 wt. % lubricant, and
0 to 5 wt. % glidant,
wherein the tablet optionally comprises an external film coating, and
wherein all wt. % are based on the total weight of the tablet, without the film coating.

US Pat. No. 10,335,345

VIBRATION DEVICE USING SOUND PRESSURE, AND HUMAN BODY STIMULATION APPARATUS COMPRISING SAME

EVOSONIC CO., LTD., Wonj...

1. A vibration device for generating vibration using sound pressure, the vibration device comprising:a lower body being open at a top thereof, and defining an accommodation space therein;
a lower bracket being open at a top and a bottom thereof, and provided in the accommodation space of the lower body;
a magnetic body fixedly provided on a bottom surface of the lower body to generate a magnetic force;
a bobbin provided in the lower bracket to be located above the magnetic body;
a voice coil provided on an outer circumference of the bobbin to interact with the magnetic body;
a damper provided on an upper surface of the bobbin, coupled to an upper surface of an edge of the lower bracket, and vertically generating vibration by interaction between the magnetic body and the voice coil;
a connection member coupled at a lower end thereof to a central portion of the damper and a central portion of the upper surface of the bobbin, and coupled at an upper end thereof with a vibration probe for stimulating a human body, thus transmitting vibration from the damper to the vibration probe;
an upper body covering an open top of the lower body, the connection member being inserted into a center on an upper surface of the upper body; and
an upper bracket being open at a bottom thereof, and accommodated in an internal space of the upper body to be coupled with the lower bracket, the connection member being inserted into an upper surface of the upper bracket.

US Pat. No. 10,335,334

EMERGENT SITUATION NOTIFICATION DURING TRANSPORT OF A PATIENT SUPPORT APPARATUS

Hill-Rom Services, Inc., ...

1. A patient-support status system comprisinga patient support apparatus adapted to support a patient thereon, the patient support apparatus including control circuitry including memory storing the identity of the patient support apparatus,
a user interface coupled to the control circuitry and monitoring for a user input associated with an emergent situation of the patient during transportation of the patient on the patient support apparatus,
a location-detection system coupled to the control circuitry of the patient support apparatus, the location detection system communicating with location identifiers in a healthcare facility to provide a real-time location of the patient support apparatus as the patient support apparatus moves through the healthcare facility, and
a transceiver coupled to the control circuitry, the transceiver communicating the patient support apparatus identity and the real-time location to a remote computer in response to receipt of the user input.

US Pat. No. 10,335,306

SUPPORTER

KOWA CO., LTD, (JP) ADVA...

1. A supporter formed of a band-shaped member, the supporter comprising:a back-contact section that is arranged substantially at the center of the band-shaped member, and that is adapted to come in contact with a wearer's back region;
protruding sections that are arranged at both sides of the back-contact section;
a pair of auxiliary band sections that defines two band-shaped members having stretchability in a longitudinal direction and in which an annular ring is arranged to be slidable over each band-shaped member; and
a pair of adjustment band sections that defines two band-shaped members having stretchability lower than the stretchability of the auxiliary band sections,
wherein each protruding section includes a stretchable portion being in contact with the back-contact section and having stretchability in the longitudinal direction and a non-stretchable portion having no stretchability,
wherein both ends of the pair of auxiliary band sections are fixed so that the two band-shaped members cross each other on the back-contact section,
wherein each of the pair of adjustment band sections is slideably inserted into the annular rings arranged in the auxiliary band sections, and
wherein the pair of adjustment band sections includes:
a first adjustment band section in which one end of the band-shaped member is fixed to the non-stretchable portion of the right protruding section and an other end of the band-shaped member is able to be fastened to the non-stretchable portion of the right protruding section, and
a second adjustment band section in which one end of the band-shaped member is fixed to the non-stretchable portion of the left protruding section and an other end of the band-shaped member is able to be fastened to the non-stretchable portion of the left protruding section.

US Pat. No. 10,335,302

SYSTEMS AND METHODS FOR USING TRANSCUTANEOUS ELECTRICAL STIMULATION TO ENABLE DIETARY INTERVENTIONS

Elira, Inc., St. Louis, ...

1. A system to generate real-time interventions in response to a patient's degree of appetite, comprising:an electrical dermal patch comprising:
a housing;
a controller positioned within the housing;
at least one electrode positioned in physical communication with the housing and adapted to be in electrical contact with the patient's skin; and,
a pulse generator positioned within the housing and in electrical communication with the controller and said at least one electrode, wherein the pulse generator is configured to generate a plurality of stimulation sessions comprising a plurality of electrical pulses defined by stimulation parameters and wherein said stimulation parameters comprise a first pulse width in a range of 10 ?sec to 10 msec, a first pulse amplitude in a range of 100 ?A to 100 mA, and a first pulse frequency in a range of 1 Hz and 100 Hz;
a first plurality of programmatic instructions stored in a non-transient memory in a client device separate from the electrical dermal patch, wherein, when executed, said first plurality of programmatic instructions is adapted to cause the client device to generate a prompt to the patient to input data indicative of the patient's degree of appetite via a microphone or a display of said client device;
a second plurality of programmatic instructions stored in a non-transient memory in the client device or another device separate from the electrical dermal patch, wherein, when executed, said second plurality of programmatic instructions determines an appetite pattern of the patient based upon said inputted data; and
a third plurality of programmatic instructions stored in a non-transient memory in the client device or another device separate from the electrical dermal patch, wherein, when executed, said third plurality of programmatic instructions determines an intervention and generates said intervention based on the appetite pattern.

US Pat. No. 10,335,294

SYSTEMS AND METHODS FOR AUTOMATICALLY TUNING POWERED PROSTHESIS IMPEDANCE CONTROL PARAMETERS

North Carolina State Univ...

1. A system for tuning powered prosthesis impedance control parameters, comprising:a powered prosthesis comprising:
a joint,
a motor mechanically coupled to the joint, the motor being configured to drive the joint,
a plurality of sensors configured to measure a plurality of gait parameters associated with a subject, and
an impedance controller configured to output a control signal for adjusting a torque of the motor;
an intelligent tuner operably connected to the powered prosthesis, wherein the intelligent tuner is configured to implement an intelligent computing algorithm for adjusting at least one of a plurality of impedance control parameters using a rule base, and wherein the rule base encodes human expert decision making using a plurality of rules that link changes in the measured gait parameters to corresponding adjustments to the impedance control parameters; and
a finite state machine operably connected to the powered prosthesis, wherein the finite state machine is configured to determine a gait cycle state based on the measured gait parameters and select a set of adjusted impedance control parameters based on the gait cycle state, wherein the impedance controller is configured to adjust the torque of the motor as a function of the measured gait parameters and the set of adjusted impedance control parameters.

US Pat. No. 10,335,285

REVISEABLE STEMLESS PROSTHESES AND METHODS

Howmedica Osteonics Corp....

1. An orthopedic revision system comprising:a base member having a collar portion and at least one stabilization portion extending distally from the collar portion; and
a stem member having an attachment portion and a shaft portion,
wherein the stem member is configured to be received at least partially through an opening in the collar portion such that the attachment portion lies adjacent the collar portion and the shaft portion lies adjacent the at least one stabilizing portion.

US Pat. No. 10,335,282

MAGNETIC JOINT REPLACEMENT

Richard A. Rogachefsky, ...

1. A hip joint prosthesis, comprising:a femoral head comprising a plurality of magnets positioned on an anterior surface of the femoral head, the plurality of magnets comprising a first femoral magnet and a second femoral magnet, the first femoral magnet configured to provide a stronger magnetic field than the second femoral magnet;
an acetabular cup corresponding to the femoral head, the acetabular cup comprising a second plurality of magnets positioned on a posterior surface of the acetabular cup, the second plurality of magnets comprising a first acetabular cup magnet and a second acetabular cup magnet, the first acetabular cup magnet configured to provide a stronger magnetic field than the second acetabular cup magnet;
wherein the femoral head is configured to rotate within the acetabular cup through a range of motion corresponding to about 0-120 degrees of hip flexion, the first femoral magnet positioned on a medial side of the anterior surface of the femoral head and the first acetabular cup magnet positioned on a lateral side of the posterior surface of the acetabular cup such that the first femoral magnet and the first acetabular cup magnet align to form the strongest magnetic force between the first femoral magnet and the first acetabular cup magnet when the femoral head is in a position corresponding to about 90-120 degrees of hip flexion.

US Pat. No. 10,335,281

CARTILAGE MOSAIC COMPOSITIONS AND METHODS

ALLOSOURCE, Centennial, ...

1. A mosaic cartilage composition comprising:a 1 mm thick cartilage sheet comprising a plurality of interconnected cartilage tiles that are separated by channels formed in the cartilage sheet, each channel having a respective depth that is less than 1 mm, and wherein perforations are formed in the cartilage sheet beneath one or more of the channels; and
a cryopreservation medium.

US Pat. No. 10,335,275

METHODS FOR DELIVERY OF HEART VALVE DEVICES USING INTRAVASCULAR ULTRASOUND IMAGING

MILLIPEDE, INC., Santa R...

24. A method of delivering an implant proximate a cardiac valve annulus, the method comprising:advancing a distal end of a delivery catheter proximate the cardiac valve annulus;
advancing the implant through the distal end of the delivery catheter proximate the cardiac valve annulus;
advancing a distal end of an ultrasound catheter proximate the cardiac valve annulus, the distal end of the ultrasound catheter including one or more ultrasonic transducers;
capturing an ultrasound image of the implant and the cardiac valve annulus with the one or more ultrasonic transducers; and
anchoring the implant to the cardiac valve annulus,
wherein the implant is a cardiac valve replacement and comprises:
a series of struts defining a tubular frame and an axis and forming a plurality of lower crowns;
a plurality of anchors coupled with the lower crowns of the frame and configured to translate axially relative to the frame to engage cardiac tissue proximate the cardiac valve annulus; and
a plurality of valve leaflets coupled with the frame.

US Pat. No. 10,335,272

APPARATUS AND METHOD FOR REPAIRING THE FUNCTION OF A DISEASED VALVE

THE CLEVELAND CLINIC FOUN...

1. An apparatus for repairing the function of a diseased valve, the apparatus comprising:a tubular first support member expandable to a first average diameter and having oppositely disposed proximal and distal first support member ends;
a tubular second support member spaced axially apart from the first support member and expandable to a second average diameter that is smaller than the first average diameter, the second support member having oppositely disposed proximal and distal second support member ends; and
a tubular graft section interconnecting the first and second support members and defining an annulus axially spaced from both the first and second support members, the tubular graft section having oppositely disposed proximal and distal graft section ends axially spaced apart by a graft section body, the proximal graft section end being connected directly to the distal first support member end and the distal graft section end being connected directly to the proximal second support member end, a diameter of the tubular graft section at the proximal graft section end being larger than a diameter of the tubular graft section at the distal graft section end, the graft section overlapping and being secured to an outer surface of one of the first and second support members and the graft section underlying and being secured to an inner surface of the other of the first and second support members.

US Pat. No. 10,335,261

VESSEL FILTER AND METHODS FOR USE

Sanford Health, Sioux Fa...

1. An apparatus comprising:a filter; and
a frame having a first end and a second end, wherein the frame includes a first support and a second support each continuously extending from the first end to the second end, wherein the first support is coupled to a first side of the filter and the second support is coupled to an opposite side of the filter, wherein the first support is directly coupled to the second support at the first end of the frame such that the frame and the filter taper to a first pointed tip at the first end of the frame, wherein the first support is directly coupled to the second support at the second end of the frame such that the frame and the filter taper to a second pointed tip at the second end of the frame, wherein the frame and the filter together define a first lumen, wherein the frame has shape memory and is movable between a first position in which the first lumen has a first diameter and a second position in which the first lumen has a second diameter, wherein in the second position, the first support and the second support are arranged spaced apart such that there is a gap between the first support and the second support, wherein the first diameter is smaller than the second diameter, wherein the frame and filter together are configured such that an entire length of the apparatus from the first end of the frame to the second end of the frame is configured to be circumferential to a second lumen of a target vessel in the second position, wherein an entire length of the first lumen defined by the frame and the filter is configured to be substantially concentric with the second lumen of the target vessel in the second position, and wherein the frame has an intermediate position such that the frame and the filter define a cone-shape at the second end of the frame such that the first lumen has the first diameter at the second end of the frame and the first lumen has the second diameter at the first end of the frame when the frame transitions from the second position to the first position.

US Pat. No. 10,335,241

METHOD AND APPARATUS FOR INTRAOPERATIVE MEASUREMENTS OF ANATOMICAL ORIENTATION

DePuy Synthes Products, I...

1. An apparatus comprising:a plurality of electronic devices, each electronic device including an internal power source and being configured to detect at least one of an orientation or a position of the electronic device with respect to earth's frame of reference in a plurality of dimensions; and
a coupler configured to removeably maintain the plurality of electronic devices in physical proximity of one another, the coupler maintaining the plurality of electronic devices in at least one of a similar orientation or a similar position;
wherein the internal power source of the electronic device is configured to be deactivated when at least a portion of the coupler is in proximity to the electronic device.

US Pat. No. 10,335,224

METHOD OF DESTROYING TISSUE CELLS BY ELECTROPORATION

AngioDynamics, Inc., Lat...

1. A method of treating a living human body by destroying tissue cells, comprising:positioning one or more electrodes over skin cells of the living human body, the skin cells of the living human body overlying fat cells of the living human body, the one or more positioned electrodes defining a target area containing fat cells to be killed in the living human body; and
treating the living human body by applying electrical pulses through the one or more positioned electrodes in an amount above an upper limit of electroporation to irreversibly open pores in membranes of the fat cells in the target area, thereby killing the fat cells in the target area.

US Pat. No. 10,335,202

LOCKABLE PEDICLE FASTENER

BLACKSTONE MEDICAL, INC.,...

1. A spinal fixation system, comprising:at least one screw having a screw head at a proximal end and wherein the screw head comprises a substantially spherical surface;
at least one body, wherein the body has a proximal portion and a distal portion;
the proximal portion comprising:
a rod receiving channel operable to receive a fixation rod;
an external attachment feature; and
a pressure cap disposed at a distal end of the proximal portion and formed integrally with the proximal portion, wherein a distal end of the pressure cap comprises an interior surface contoured to fit against the substantially spherical surface of the screw head;
the distal portion comprising:
an internal attachment feature operable to engage the external attachment feature of the proximal portion, wherein the engaging of the internal attachment feature with the external attachment feature secures the proximal portion to the distal portion;
a screw head receiving chamber disposed at a distal end of the distal portion operable to retain the screw head within the body; and
an external surface operable to engage a drive tool that operates to join the internal attachment feature with the external attachment feature and further cause the pressure cap to apply a bias against the screw head;
wherein a majority of a diameter of the external surface is greater than an outer diameter of the proximal portion;
wherein the screw head receiving chamber allows multi-axial movement of the body in relation to the screw when the pressure cap is disengaged from the screw head; and
wherein the difference in diameter between the external surface and the proximal portion allows the body to be secured in a mono-axial position in relation to the screw when the external surface is engaged after the pressure cap has been biased against the screw head.

US Pat. No. 10,335,189

SYSTEMS AND METHODS FOR PERCUTANEOUS DIVISION OF FIBROUS STRUCTURES

PAVmed Inc., New York, N...

1. A device for dividing a fibrous structure, the device comprising:a catheter having a proximal end, a distal end, and lumen extending therebetween;
an expandable member positioned near the distal end of the catheter and in fluid communication with the lumen of the catheter so that the expandable member can be biased between an inflated state and a deflated state, the expandable member having a cross-sectional shape that expands radially in a first direction more than it expands in a second direction to provide the expandable member with an elongated cross-sectional shape when inflated; and
a cutting element situated on an outer surface of the expandable member at a location that expands in the second direction, such that, as the expandable member expands in the first direction and pushes the fibrous structure in opposing lateral directions, the fibrous structure is pulled taut against the cutting element to allow tensioning of the fibrous structure against a discrete portion of the cutting element, wherein the cutting element is a blade configured to apply a mechanical force to weaken or cut the fibrous structure.

US Pat. No. 10,335,176

ROTARY INPUT FOR LEVER ACTUATION

Intuitive Surgical Operat...

1. A medical device comprising:a lever comprising an applied force position, a load position, and a fulcrum position;
a first capstan;
a second capstan;
a first cable extending from the applied force position of the lever to the first capstan, the first cable wrapping around the first capstan;
a second cable extending from the applied force position of the lever to the second capstan, the second cable wrapping around the second capstan;
a surgical end effector; and
a rod coupled between the load position of the lever and the surgical end effector.

US Pat. No. 10,335,167

DRILL BIT AND METHOD FOR PRODUCING A DRILL BIT

SURGIBIT IP HOLDINGS PTY ...

1. A medical device for use during surgery, said device comprising a shaft and a tapered tip for drilling into a surface of body material; the tip including a plurality of faces, each face having at least two sub-faces formed and arranged to define a generally pyramidal shaped remote end terminating in an extreme drill point whereby the remote end is adapted to pierce the surface and thereby locate the tip prior to drilling; and whereinthe shaft and tip includes at least one flute having a first portion and a second portion;
wherein the first portion is generally helical and extends at least partially along the shaft;
wherein the second portion is formed in the tip and associated with a respective sub-face and extends partway along the tip behind the drill point;
wherein the second portion includes a groove formed in the tip and adjacent at least one edge of the respective sub-face, thereby to enhance the cutting ability of the tip;
wherein the first portion intersects with the second portion to direct debris away from the tip during drilling; and
wherein the sub-faces are asymmetrically offset about a center line of the respective face.

US Pat. No. 10,335,146

SURGICAL FASTENER APPLYING APPARATUS, KITS AND METHODS FOR ENDOSCOPIC PROCEDURES

Coviden LP, Mansfield, M...

1. An endoscopic surgical device, comprising;a handle assembly including a handle housing and a trigger operatively connected to the handle housing, and a drive mechanism actuatable by the trigger, wherein the handle housing includes a tooth projecting from a surface thereof, wherein the handle assembly includes a ferrule removably and rotatably connected to the handle housing, the ferrule defining an aperture therein that is in operative alignment with the drive mechanism of the handle assembly, the ferrule including a tooth projecting radially into the aperture of the ferrule, the ferrule having:
a first position wherein the tooth of the ferrule is radially aligned with the tooth of the handle housing; and
a second position wherein the tooth of the ferrule is radially out of alignment with the tooth of the handle housing; and
an endoscopic assembly selectively connectable to the handle assembly, the endoscopic assembly including:
an outer tube defining a lumen therethrough and having an outer helical thread disposed within the lumen thereof, the outer tube defining a proximal end and a distal end;
an inner tube rotatably supported in the outer tube, the inner tube defining a lumen therethrough and having a proximal end and a splined distal end, wherein the splined distal end of the inner tube is defined by a pair of opposed longitudinally extending tines and a pair of opposed longitudinally extending channels;
a plurality of surgical anchors loaded in the lumen of the inner tube of the endoscopic assembly, wherein each anchor of the plurality of surgical anchors includes a threaded body portion, and a head portion defining a pair of opposed radially outer threads and a pair of opposed radial recesses, wherein the pair of radial recesses of each head portion receives a respective tine of the pair of opposed longitudinally extending channel of the inner tube and wherein the pair of opposed radially outer threads of each head portion projects from the pair of opposed longitudinally extending channels of the inner tube and engage the inner helical thread of the outer tube; and
a connector having:
an outer connector member non-rotatably connected to the proximal end of the outer tube and being non-rotatably connectable to the handle assembly, the outer connector member including a channel formed therein, wherein:
the channel of the outer connector member receives the tooth of the handle housing when the endoscopic assembly is connected to the handle assembly; and
the tooth inhibits rotation of the outer connector member when the trigger is actuated to rotate the inner connector member of the endoscopic assembly; and
an inner connector member non-rotatably connected to the proximal end of the inner tube and being non-rotatably connectable to the drive mechanism, wherein the outer connector member and the inner connector member are rotatable with respect to one another.

US Pat. No. 10,335,135

FIXING DEVICE FOR SUTURE THREADS TO BE INSERTED INTO A BONE TISSUE

NCS LAB S.R.L., Carpi (I...

1. A fixing device for suture threads to be inserted into a bone structure, comprising a first portion (11, 21) and a second portion (12, 22), the device having an undeployed state, a deployed state, and a longitudinal dimension, the deployed state being a state when the device is deployed in a bone structure, the first portion (11, 21) being provided with a first eyelet (10, 20) or eye effectively sized to receive a first suture thread (4) therethrough, the first eyelet or eye defining an opening which extends through the device in a direction substantially perpendicular to the longitudinal dimension in the undeployed state, the second portion (12, 22) exhibiting a second eyelet or eye effectively sized to receive a second suture thread (4) therethrough, the second portion (12, 22) comprising an engagement portion which is effectively sized and shaped such that it can effectively contact and engage an interior surface of a transosseus seating or hole (5) afforded in the bone structure to thereby stably couple the device with the bone structure, the second portion (12, 22) having a neck portion located between the engagement portion and the first portion, the engagement portion being spaced apart from the first portion, the engagement portion having a medial portion and a distal portion, the medial portion being located between the neck portion and the distal portion, the device being configured so that, in use, the engagement portion is inserted, distal portion first, into the transosseus seating or hole (5), the neck portion having a first width transverse to the longitudinal dimension, the first portion comprising a mushroom-shaped portion having a second width transverse to the longitudinal dimension, the second width being larger than the first width in both the undeployed state and the deployed state, the second width being larger than the first width when the first eyelet or eye defines the opening in the undeployed state, the mushroom-shaped portion being integral with the neck portion, the neck portion being integral with the engagement portion, the mushroom-shaped portion extending beyond the neck portion in a first direction transverse to the longitudinal dimension in both the undeployed state and the deployed state, the mushroom-shaped portion extending beyond the neck portion in a second direction transverse to the longitudinal dimension in both the undeployed state and the deployed state, the second direction being opposite to the first direction, and wherein at least the second portion (12, 22) is elastically deformable in order to enable effective coupling to the transosseus seating or hole (5).

US Pat. No. 10,335,124

MARKER DELIVERY DEVICE WITH ADAPTOR FOR BIOPSY SITE MARKING AND METHOD OF USE THEREOF

Devicor Medical Products,...

1. A marker delivery device for marking a biopsy site, comprising:a cannula having a proximal end, a distal end, and a marker exit proximate to the distal end, wherein the cannula is configured to receive a marker deploying rod for deploying a marker through the marker exit;
a handle; and
a tapered adaptor portion disposed between the handle and the proximal end of the cannula, the tapered adaptor portion being configured to engage different inner surfaces of a plurality of obturator sleeves into which the tapered adaptor portion is received, wherein the tapered adaptor portion includes:
an outer surface,
a first radially extending feature extending from the outer surface of the tapered adaptor portion, and
a second radially extending feature extending from the outer surface of the tapered adaptor portion,
wherein the tapered adaptor portion engages each of the different inner surfaces of the plurality of obturator sleeves at a position defined by one of the first radially extending feature or the second radially extending feature.

US Pat. No. 10,335,122

MULTI-CHAMBER TISSUE SAMPLE CUP FOR BIOPSY DEVICE

Devicor Medical Products,...

1. A biopsy device comprising:(a) a body;
(b) a needle extending distally from the body;
(c) a cutter longitudinally translatable relative to the needle, wherein the cutter defines a cutter lumen; and
(d) a tissue sample holder including,
(i) a rotatable member, wherein at least a portion of the rotatable member defines an inner chamber divided by a plurality of tray walls extending radially inwardly from an outer wall of the rotatable member,
(ii) an individual sample tray including a single sample chamber, wherein the single sample chamber is configured to receive only a single tissue sample, and
(iii) one or more bulk sample trays, wherein the bulk sample tray is configured to receive a plurality of tissue samples, wherein each bulk sample tray includes a distal end wall having a single sample opening for receiving tissue samples therethrough.

US Pat. No. 10,335,117

PROBE FOR ULTRASONIC DIAGNOSTIC APPARATUS

SAMSUNG ELECTRONICS CO., ...

1. A probe for an ultrasonic diagnostic apparatus, the probe comprising:a case;
a piezoelectric object provided at an interior portion of the case and configured to generate an ultrasonic wave;
a backing layer provided at a rear portion of the piezoelectric object and configured to block the generated ultrasonic wave from propagating through and out of a rear portion of the backing layer;
an acoustic matching layer provided at a front portion of the piezoelectric object and configured to match a sound impedance of the piezoelectric object with a sound impedance of a subject;
an acoustic lens provided at a front portion of the acoustic matching layer and configured to concentrate the generated ultrasonic wave and facilitate a propagation of the concentrated ultrasonic wave signal toward the subject; and
a pad which is detachably provided at a front side of the acoustic lens, the pad comprising a layer configured to directly contact a skin of the subject, the layer being constructed of an ultrasonic wave mediating material,
wherein the acoustic lens comprises a concave portion configured to facilitate a performance of a diagnosis with respect to the subject along a curved surface of the subject, and
wherein the concavity of the concave portion of the acoustic lens is a concavity with respect to the skin of the subject.

US Pat. No. 10,335,098

PANORAMIC IMAGING APPARATUS AND DIAGNOSTIC IMAGING METHOD IN SAME APPARATUS

AXION JAPAN CO., LTD., S...

1. A dental panoramic imaging apparatus, comprising:an X-ray source irradiating X-rays;
a detector receiving the X-rays, converting the X-rays to digital electric signals pixel by pixel, and outputting, as frame data, the electric signal at a constant rate;
a moving member moving the X-ray source and the detector around a jaw portion of a subject being examined, the X-ray source and the detector being located opposite to each other with the subject therebetween;
a data storage unit storing therein the frame data outputted from the detector while the moving member moves the X-ray source and the detector around the jaw portion of the subject;
a display unit;
a processor; and
an operating unit operated by a user;
wherein the processor is configured to, responsively to user's instructions issued via the operating unit,
generate data of an optimally focused panoramic image of a section along curved dentitions in the jaw portion, based on the frame data stored in the data storage unit;
display the generated optically focused panoramic image on the display unit;
superimposedly display both information and a measurement line on the panoramic image displayed on the display unit, the information indicating a restricted range in a vertical direction on the panoramic image, the vertical direction being approximately vertical to a lateral direction which is along the dentitions, the measurement line positioned within the restricted range on the panoramic image in the vertical direction, wherein said measurement line is provided for analyzing a degree of loss of alveolar bone supporting teeth at a tooth row of the jaw portion of the subject;
designate; on the panoramic image, via interactive operator input on the input unit, a position of the measurement line by changing a position of the measurement line superimposed on the panoramic image within the restricted range in the vertical direction, such that the position of the measurement line is decided based on a feature point or a reference point associated with the feature point, the feature point indicating features of both one or more teeth being targeted among the whole teeth and a support portion which supports the one or more of the whole teeth at the alveolar bone;
measure a length on the panoramic image displayed on the display unit, wherein the length is decided based on the feature point or the reference point designated; and
analyze the degree of loss of the support portion of the alveolar bone, based on the measured length.

US Pat. No. 10,335,092

BUILDING PREDICTED FUTURE MEDICAL PROFILES

Pivotal Software, Inc., ...

1. A computer-implemented method comprising:receiving, from a user, a request to compute a predicted future medical profile for a first patient having a future age N that is at least M*2 years beyond an initial age a1 using only M years of data, wherein the future medical profile assigns a score to each of a plurality of characteristics, each score for each characteristic representing a respective likelihood of the first patient having the respective characteristic at the future age N;
obtaining, by one or more computers, a current medical history of the first patient, the current medical history comprising data representing a plurality of current characteristics of a first patient having an initial age a1, a1 being less than N;
determining, using the current medical history of the first patient, an initial predicted medical profile of the first patient at a future time when the first patient will have a second age a2, wherein the second age a2 is no more than M years beyond the initial age a1;
obtaining M years of medical history for a plurality of other patients starting at a respective time when each of the other patients has a respective age that is at least the second age a2 and covering a respective time at which each of the other patients has attained the age N, wherein each medical history for each of the other patients indicates a respective age at which a particular characteristic occurred for the other patient;
computing a plurality of nearest neighbors to the first patient, each nearest neighbor having respective characteristics occurring at the second age a2 that are most similar to the initial predicted medical profile of the first patient at the future time at which the first patient has the second age a2;
adding, to the predicted future medical profile for the first patient, one or more non-matching characteristics that each occur in at least one respective medical history of a respective nearest neighbor of the plurality of nearest neighbors but that does not occur in the medical history of the first patient;
generating a respective score for each of the one or more non-matching characteristics that each occur in at least one respective medical history of a respective nearest neighbor of the plurality of nearest neighbors but that does not occur in the medical history of the first patient, wherein the score for each non-matching characteristic represents a measure of how frequently the non-matching characteristic occurs in the medical histories of the plurality of nearest neighbors;
generating a presentation of the future medical profile for the first patient, the presentation including data representing a range of predicted outcomes for each of the one or more non-matching characteristics and a respective score for each of the one or more non-matching characteristics; and
providing the presentation of the future medical profile for the first patient for display on a display device to the user.

US Pat. No. 10,335,079

ASSESSING COGNITION USING ITEM-RECALL TRIALS WITH ACCOUNTING FOR ITEM POSITION

Medical Care Corporation,...

1. A computer-implemented method comprising:receiving data comprising responses, and lack thereof, for items of a cognitive test, wherein the cognitive test comprises multiple item-recall trials used to assess cognition;
processing the data using a stochastic model of a cognitive process, in which a conditional probability distribution of future states of the cognitive process depend only upon a present state; and
encoding a result of the processing on a non-transitory computer-readable medium to supply the result to a computer device for use in an assessment related to cognition;
wherein the processing using the stochastic model comprises representing recall of an item in the multiple item-recall trials using distinct cognitive states; and
wherein the processing using the stochastic model comprises adjusting separate memory storage and retrieval parameters for each of the distinct cognitive states in the modeled cognitive process to account for position of the items in each respective trial of the multiple item-recall trials.

US Pat. No. 10,335,067

OPTICAL UNIT AND OPTICAL ANALYSIS DEVICE

NEC SOLUTION INNOVATORS, ...

1. An optical unit comprising:a light emitter that irradiates an analysis target with light;
a plurality of light receivers that receive light that has been reflected or diffused by the analysis target;
a mounting substrate on which the light emitter and the plurality of light receivers are mounted; and
a plate-shaped member having optical transparency,
wherein the plate-shaped member is arranged so as to cover the light emitter and the plurality of light receivers that are mounted on the mounting substrate, and
positions of the light emitter, the light receivers, and the plate-shaped member are respectively set such that, in a case where the analysis target is in contact with the plate-shaped member, light emitted from the light emitter is incident on two or more of the light receivers after being reflected or diffused by the analysis target,
wherein the optical unit further comprises a cooler,
the light emitter comprises, between a light-emitting diode and the mounting substrate, a heat transmitter for transmitting heat generated in the light-emitting diode to the mounting substrate,
the cooler is arranged in contact with a surface of the mounting substrate on which the light emitter and each light receiver are not mounted, and
the mounting substrate comprises:
a conduction channel that is connected to the light-emitting diode and a light receiving photodiode of each light receiver;
a wiring that is formed inside the mounting substrate and is connected to the conduction channel; and
a heat channel that connects the wiring and the cooler.

US Pat. No. 10,335,055

KINETIC ASSESSMENT AND ALIGNMENT OF THE MUSCULAR-SKELETAL SYSTEM AND METHOD THEREFOR

Orthosensor Inc., Daina ...

1. An orthopedic measurement system for kinetic assessment comprising:a device having a surface configured to couple to a joint of a musculoskeletal system comprising at least one sensor configured to measure one or more parameters wherein the device includes a tracking system;
a computer configured to receive measurement data from the at least one sensor and the tracking system;
a display coupled to the computer, wherein the display includes a graphical user interface, wherein a memory and one or more processors are configured to execute one or more programs stored in the memory, wherein the computer is configured to receive measurement data from the at least one sensor of the device, wherein the graphical user interface includes a graphical depiction of a portion of a surface of the device that is configured to couple to the joint, wherein a contact point is displayed on the graphical depiction of the portion of the surface of the device, wherein the computer is configured to use the measurement data to calculate a contact point location on the graphical depiction of the portion of the surface of the device, and wherein the contact point is configured to move in real-time corresponding to movement of the joint.

US Pat. No. 10,335,052

DETECTION OF PULMONARY VEIN ISOLATION

UNIVERSITEIT GENT, Ghent...

1. A device for analyzing electrophysiological data, the device comprising:at least one electrode for generating at least one electrocardiogram recorded in a junction region between a pulmonary vein and a left atrium of the heart in a subject,
a processing means adapted for: determining a morphology classification representative of a waveform shape for each of the at least one electrocardiogram, determining a first value representative of a likelihood that the at least one electrocardiogram comprises a pulmonary vein potential component, wherein said determining the first value takes said morphology classification into account, and
for generating a signal indicative of a detected presence of the pulmonary vein potential component when the first value satisfies a first predetermined condition and a signal indicative of a detected absence of the pulmonary vein potential component when the first value satisfies a second predetermined condition,
wherein the processing means is furthermore adapted for determining at least one morphological parameter indicative of at least one waveform feature for each of the at least one electrocardiogram and determining a second value representative of said likelihood that the at least one electrocardiogram comprises said pulmonary vein potential component, wherein this determining of the second value takes said at least one morphological parameter and said morphology classification into account, and
wherein the processing means is furthermore adapted for generating a signal indicative for the detected presence of the pulmonary vein potential component when the second value satisfies a third predetermined criterion.

US Pat. No. 10,335,040

DEVICE FOR MEASURING THE INFRARED OUTPUT OF THE ABREU BRAIN THERMAL TUNNEL

Geelux Holdings, Ltd., T...

1. A sensing device configured to interface with a human Abreu brain thermal tunnel (ABTT) terminus of a patient, the sensing device comprising:a handle portion;
a body portion including a first end and a second end, said handle portion being pivotally mounted on the second end of the body portion;
a viewing portion mounted on an upper side of the body portion, the viewing portion including a display configured to extend from the body portion into a patient's field of view; and
a sensing portion including a sensor mounted on a free end of the sensing portion, said sensing portion being rotatably mounted on the first end of the body portion and said sensing portion being angled away from the body portion, the free end of the sensing portion being rotatably movable with respect to the body portion to receive a signal from the ABTT terminus, the sensing portion including a field of view to capture at least the signal from a center portion of the ABTT terminus, and the sensing portion oriented at an angle of 75 degrees or less with respect to a longitudunal axis of the body portion.

US Pat. No. 10,335,034

DEPENDENCY-BASED STARTUP IN A MULTI-MODALITY MEDICAL SYSTEM

VOLCANO CORPORATION, San...

1. A dependency-based startup method in a multi-modality medical processing unit, the method comprising:receiving, by a system controller of the multi-modality medical processing unit, initialization information about:
a resource arbiter component configured to manage sharing of system resources,
a workflow controller component configured to govern a multi-modality medical sensing workflow,
a first medical sensing modality component configured to communicate with a first medical sensing device configured to be coupled to the multi-modality medical processing unit, wherein the first medical sensing modality component is associated with intravascular ultrasound (IVUS) imaging by the first medical sensing device, and
a second medical sensing modality component configured to communicate with a second medical sensing device configured to be coupled to the multi-modality medical processing unit;
receiving, by the system controller, dependency information about the resource arbiter component, the workflow controller component, and the first and second medical sensing modality components, wherein the dependency information indicates that both the first medical sensing modality component and the second medical sensing modality component depend on the resource arbiter component and the workflow controller component;
deriving, by the system controller, a start order based on the dependency information, wherein the start order comprises a plurality of startup levels organized such that the first and second medical sensing modality components occupy the same startup level and such that the first and second medical sensing modality components come later in the start order than the resource arbiter component and the workflow controller component;
determining, by the system controller, whether the first medical sensing device is coupled to the multi-modality medical processing unit;
determining, by the system controller, whether the second medical sensing device is coupled to the multi-modality medical processing unit; and
starting the resource arbiter component, the workflow controller component, and the first and second medical sensing modality components in the multi-modality medical processing unit according to the start order, wherein the resource arbiter component and the workflow controller component are started during every startup sequence, wherein the first medical sensing modality component is only started when the first medical sensing device is coupled to the multi-modality medical processing unit, and wherein the second medical sensing modality component is only started when the second medical sensing device is coupled to the multi-modality medical processing unit.

US Pat. No. 10,335,032

SYSTEMS AND METHODS FOR QUANTIFICATION OF, AND PREDICTION OF SMOKING BEHAVIOR

Carrot, Inc., Redwood Ci...

1. A method identifying a smoking behavior of an individual, the method comprising:recording a plurality of behavioral data regarding a behavior of the individual;
obtaining a plurality of biologic data from the individual;
identifying a smoking exposure over a period of time of the individual using the plurality of biologic data without affecting the smoking behavior of the individual;
compiling a behavior summary, where the behavior summary includes an association of at least one of the plurality of behavioral data and the smoking exposure; and
providing at least a portion of the behavior summary to a user interface structured to display the at least one of the plurality of behavioral data in association with the smoking exposure, where the user interface is configured to permit the individual to observe data in the behavior summary to inform the individual about the smoking behavior.

US Pat. No. 10,334,964

HOLDER ASSEMBLY

INVENTORY SYSTEMS GMBH, ...

1. A holder assembly for hanging goods to be displayed at a point of sale, comprising:at least one elongated holding member at which goods are to be hanged and to be arranged in a row of goods one behind the other so that the hanging goods may be slid along the at least one elongated holding member to a removal position at an end of the at least one elongated holding member where a good may be removed from the at least one elongated holding member; and
a carrier to which the at least one elongated holding member is mounted and at which an electronic detection element is provided,
wherein the at least one elongated holding member is displaceable between a first position and a second position with a motion component in the vertical direction,
wherein the at least one elongated holding member is configured to be displaced from the first position to the second position in order to allow a removal of at least one foremost good of a row of hanging goods arranged at the at least one elongated holding member from the at least one elongated holding member so that the at least one elongated holding member is displaced from the first position to the second position every time one good is removed from the at least one elongated holding member, and
wherein the electronic detection element is configured to detect a displacement of the at least one elongated holding member from the first position to the second position for emitting at least one signal every time one good is removed from the at least one elongated holding member.

US Pat. No. 10,334,956

ONE-PIECE MATTRESS SUSPENSION DEVICE

TOURNADRE SA STANDARD GUM...

1. A one-piece suspension device for interposing between a mattress and a support structure, the device comprising:a platform defining a bearing plane for the mattress;
a fastener point for fastening to the support structure; and
a resilient section that is more resilient than the platform in a direction perpendicular to the bearing plane, being interposed between the platform and the fastener point in the direction perpendicular to the bearing plane in order to absorb compression forces, and including an angled element having a first arm and a second arm, a first elastic hinge at a first end of the first arm, and a second elastic hinge connecting a second end of the first arm to the second arm and forming a bend in such a manner that the first arm presents an angle relative to said bearing plane that is more pronounced than that presented by the second arm, the second elastic hinge being more flexible than the first elastic hinge; and
the one-piece suspension device being shaped in such a manner that any axis perpendicular to said bearing plane and passing through the one-piece suspension device intersects the one-piece suspension device along a single intersection segment.

US Pat. No. 10,334,953

FURNITURE, LOAD SUPPORT MEMBER FOR CHAIR, AND CHAIR

OKAMURA CORPORATION, Kan...

1. A load support member for a chair which is included in a chair, comprising:a frame member which is a strength member which includes a pair of rod members which is separated from each other in a width direction of the chair and is disposed to be approximately parallel to each other; and
an exterior material which includes a front extension material disposed on a load receiving surface side of the chair and a rear extension material disposed on a side opposite to the load receiving surface which are joined to each other on one end edge in a length direction of the rod member and both end edges in the width direction, the exterior material being formed in a bag shape having an opening portion continuous in the width direction on the other end edge side in the length direction and covering the frame member through the opening portion from one end side in the length direction of the frame member,
wherein a support portion is provided on each of inner surfaces facing each other of the pair of rod members, and
wherein an interior material having a repulsive force with respect to a load in a surface perpendicular direction is bridged between the pair of rod members by being supported by the support portion, the interior material being disposed between the front extension material and the rear extension material,
wherein a spacer surface material is disposed between the front extension material and the interior material, and
wherein a repulsive force of the spacer surface material with respect to the load in the surface perpendicular direction is relatively smaller than the repulsive force of the interior material with respect to the load in the surface perpendicular direction.

US Pat. No. 10,334,946

MOVABLE CABINETS

CABINETICS INNOVATIONS LT...

1. A Highly Hung Vertically Moveable Cabinet (HHVMC), comprising:a cabinet having a bottom and a top essentially parallel thereto;
an electrical motion system including:
a first bracket configured for attachment to a ceiling,
a second bracket configured for attachment to said ceiling independently of said first bracket and
an electric tubular motor for wrapping a curtain attached between the cabinet and said first bracket; said electrical motion system configured to move the cabinet to a predetermined distance of at least 500 mm in a first direction and in a second opposite direction, both first direction and second direction being essentially normal to the bottom and top;
a retractable belt configured to remain attached between the cabinet and said second bracket independently from said tubular motor; said retractable belt passively extending and retracting as said cabinet is lowered and raised respectively;
a brake attached to said retractable belt to stop said extending in response to a sudden increased movement; and
switches coupled to the electrical motion system, to allow selection of movement in the first or second direction.

US Pat. No. 10,334,881

ELECTRONIC VAPORIZER

FUMA INTERNATIONAL, LLC, ...

1. An apparatus comprising:a power source,
wherein the power source includes a battery,
wherein the power source includes an electrically conductive portion; and
a cartridge having a housing that comprises an interior,
wherein the housing includes a first end and a second end that is opposite the first end, wherein the housing includes a first aperture on the first end and a second aperture on the second end,
wherein the housing includes an airflow passageway that extends centrally and axially with respect to the housing intermediate of the first aperture on the first end of the housing and the second aperture on the second end of the housing,
wherein the airflow passageway is configured to allow an airflow through the cartridge from the first aperture to the second aperture of the housing,
wherein the first end of the housing includes an electrically conductive portion that is adapted to mechanically and electrically couple to the electrically conductive portion of the power source,
wherein the housing includes a solution holding medium adapted to hold a solution in the interior of the housing,
wherein the housing includes a heating element located in the interior of the housing, wherein the heating element extends transversely across the airflow passageway, wherein the airflow through the passageway passes on both transverse sides of the element,
wherein the solution holding medium surrounds the airflow passageway and the heating element in the interior of the housing and intermediate of the first end and the second end,
wherein the heating element is electrically configured to vaporize at least a portion of the solution to be contained in the solution holding medium for oral provision to an individual in an airflow from the second aperture responsive to electrical power received from the battery through the electrically conductive portions of the cartridge and the power source.

US Pat. No. 10,334,880

AEROSOL DELIVERY DEVICE INCLUDING CONNECTOR COMPRISING EXTENSION AND RECEPTACLE

RAI Strategic Holdings, I...

1. An aerosol delivery device, comprising:a control body including an electrical power source and a first connector portion; and
a cartridge comprising:
a reservoir configured to contain an aerosol precursor composition;
an atomizer comprising a heating element configured to heat the aerosol precursor composition received from the reservoir to produce an aerosol; and
a second connector portion,
the first connector portion and the second connector portion being configured to releasably engage each other,
the first connector portion comprising an extension electrically coupled to the electrical power source and the second connector portion comprising a receptacle configured to receive the extension, the receptacle comprising flexible heating terminals electrically coupled to the heating element of the atomizer and configured to form a mechanical connection with the extension by mechanically engaging a detent formed on the extension, the extension comprising a plurality of contact sections positioned along a longitudinal length thereof, the contact sections being electrically insulated from one another by at least one spacer and being configured to form an electrical connection with the receptacle, the receptacle being configured to receive electrical power from the extension.

US Pat. No. 10,334,871

SYSTEM, DISPOSABLE CARTRIDGE, AND METHOD FOR THE PREPARATION OF A LIQUID PRODUCT

Apiqe Holdings, LLC, Tor...

1. System for the preparation of a liquid food product, which system comprises:a) a disposable cartridge filled with a single serve portion of a liquid ingredient to be combined with a base liquid for the preparation of a liquid product, the disposable cartridge comprising:
a cartridge body with a bottom and a top, the body delimiting a reservoir that is filled with a single serve portion of a liquid ingredient,
wherein the cartridge body has an aperture in communication with said reservoir, which aperture is hermetically sealed by a sealing film, said sealing film having a portion that covers said reservoir,
wherein cartridge body is provided with one or more dispensing passages arranged to dispense the liquid ingredient from the reservoir,
b) a dispensing apparatus, the apparatus comprising:
a holder adapted to accommodate and retain the disposable cartridge at a dispensing location in the apparatus,
a pressurized gas source,
wherein the apparatus is adapted to bring said pressurized gas source in direct communication with the reservoir of the disposable cartridge so as to allow said liquid ingredient therein to be pressurized by said gas thereby assisting the dispensing thereof from the reservoir via said one or more dispensing passages,
wherein the system is adapted to create one or more openings in said portion of the sealing film that covers the reservoir, and
wherein the dispensing apparatus further comprises a pressurization dome member having a peripheral gas seal, which is adapted to sealingly engage the disposable cartridge around a location where said one or more openings are created in said sealing film to allow entry of said pressurized gas into the reservoir,
and in that the pressurized gas source is connected to said dome member and is adapted to feed pressurized gas beneath said dome member within the contour of the peripheral gas seal sealingly engaging the disposable cartridge, so as to allow said liquid ingredient in said reservoir to be pressurized by said gas via the one or more openings in said sealing film, thereby assisting the dispensing of the liquid ingredient from the reservoir via said one or more dispensing passages.

US Pat. No. 10,334,860

DOUGH STRETCHER

Somerset Industries, Inc....

1. A dough stretcher comprising:(a) a drive shaft mounted to rotate on a vertical system axis;
(b) a mechanism for rotating the drive shaft at a speed in the range of between 40 RPM and 100 RPM;
(c) a lower platen shaft having a bottom end, a top end, and an axis, the bottom end attached to the drive shaft and extending upwardly such that the lower platen shaft axis is at a tilt angle from the system axis in the range of from 1° to 4°;
(d) a lower platen with a top surface and a bottom surface, the bottom surface rotatably attached to the top end of the lower platen shaft such that the lower platen top surface rotates perpendicularly about the lower platen shaft axis; and
(e) an upper platen with a flat bottom surface and a center, the upper platen mounted above the lower platen to reciprocate vertically with the upper platen center on a system axis.
US Pat. No. 10,336,649

CERAMIC COMPOSITION FOR COATING METALLIC SURFACES, METHOD AND RESULTING CERAMIC LAYER

TORRECID, S.A., Alcora (...

1. A ceramic composition for the coating of metallic surfaces by means of thermal treatment that comprises:a. at least one frit whose percentage by weight is between 40% and 82%,
b. at least one refractory compound with a melting point higher than 1600° C., and
c. at least one synthetic compound comprising one or more elements selected from the group consisting of Co, Ni, Cu, Fe, Mo, Mn Cr, and a combination thereof;
wherein the composition by weight of the at least one frit comprises SiO2 between 55% and 70% by weight, R2O between 7% and 20% by weight, RO between 0% and 15% by weight, MOx between 0% and 8% by weight, MO2 between 0% and 7% by weight, Al2O3 0.5% and 8% by weight, and B2O3 between 3% and 10% by weight; where R2O represents at least one oxide selected from the group consisting of Li2O, Na2O, K2O and a combination thereof, where RO represents at least one oxide selected from the group consisting of ZnO, MgO, CaO, BaO and a combination thereof, where MOx represents at least one oxide selected from the group consisting of CuO, MnO2, Fe2O3, MoO3, CoO, NiO and a combination thereof, and where MO2 represents at least one oxide selected from the group consisting of TiO, CeO2 and a combination thereof.
US Pat. No. 10,335,371

SOLID PHARMACEUTICAL DOSAGE FORM SUITABLE FOR USE AS DRINKING WATER MEDICATION

Universiteit Gent, (BE) ...

1. A method for the preparation of a spray-dried solid pharmaceutical multiparticulate dosage form, the method comprising:preparing a suspension comprising a pharmaceutical non-solubilized active ingredient, a non-ionic surfactant having an Hydrophilic Lipophilic Balance (HLB) of at least 8 and water;
milling the suspension;
adding a maltodextrin to the milled suspension; and
spray-drying the milled suspension.
US Pat. No. 10,335,376

RALOXIFENE SPRINKLE COMPOSITION

Sun Pharmaceutical Indust...

1. A sprinkle capsule composition comprising a plurality of particulates, wherein each particulate comprises:a) a core comprising raloxifene; and
b) a taste-masking coating over the core to form coated cores having a D90 particle size of less than or equal to 900 ?m;
wherein, the particulates are stable when sprinkled on a soft food and wherein raloxifene is present in an amount from about 10% to about 80% based on the total weight of the composition.
US Pat. No. 10,334,872

SMOKELESS TOBACCO PRODUCT, SMOKELESS TOBACCO PRODUCT IN THE FORM OF A SHEET, EXTRUDABLE TOBACCO COMPOSITION, METHOD FOR MANUFACTURING A SMOKELESS TOBACCO PRODUCT, METHOD FOR DELIVERING SUPER BIOAVAILABLE NICOTINE CONTAINED IN TOBACCO TO A USER, AND PACKAG

PHILIP MORRIS PRODUCTS S....

1. A smokeless tobacco product comprising a sheet made by extruding or hot melt shaping a nonaqueous composition comprising at least one water soluble thermoplastic polymer and tobacco, wherein the tobacco is present in an amount of less than 100 mg in a single dose of the product such that a user's maximum measured nicotine plasma concentration is greater than 4 ng/ml, the sheet comprising a matrix comprising the at least one thermoplastic polymer and the tobacco distributed in the matrix, the matrix being soluble in a user's mouth and resulting in sustained release of nicotine to the user.
US Pat. No. 10,335,385

COMPOSITION CONTAINING NON-POLAR COMPOUNDS

Virun, Inc., Pomona, CA ...

1. A liquid emulsion concentrate composition, comprising:an emulsion stabilizer that is a fatty acid-modified carbohydrate-based macromolecule in an amount between more than 1% and up to 5%, by weight, of the concentrate composition;
a surfactant that is a PEG-derivative of Vitamin E, wherein the surfactant is present in an amount between 3% and 16%, by weight, of the concentrate composition;
a polar solvent in an amount between 40% and 60%, by weight, of the concentrate composition; and
one or more non-polar compounds that comprise non-polar active ingredients selected from among polyunsaturated fatty acids, omega-3 fatty acids, omega-6 fatty acids, omega-9 fatty acids, conjugated fatty acids, coenzyme Q-containing active ingredients, alpha lipoic acid, carotenoid-containing active ingredients and phytochemicals, wherein the one or more non-polar compounds is/are present in a total amount between 35% and 50%, inclusive, by weight, of the concentrate composition.
US Pat. No. 10,335,391

STABILIZED OXYMETAZOLINE FORMULATIONS AND THEIR USES

ACLARIS THERAPEUTICS, INC...

1. A method of treating facial erythema associated with rosacea in a patient in need of such treatment, comprising topically administering once daily to the site of erythema on the face of the patient a pharmaceutical composition comprising 1.0% w/w oxymetazoline hydrochloride thereof as the sole active ingredient, wherein the patient experiences no rebound or worsening of facial erythema post-treatment.
US Pat. No. 10,336,929

METHOD OF PRODUCING HEAT CONDUCTIVE SHEET

DEXERIALS CORPORATION, T...

1. A method of producing a heat conductive sheet, the method comprising:dispersing a fibrous filler in a binder resin to prepare a heat conductive sheet-forming composition;
forming a molded block using the prepared heat conductive sheet-forming composition according to an extrusion molding method or a die molding method;
slicing the formed molded block into a sheet;
pressing a sliced surface of the obtained sheet to smooth the sliced surface; and
disposing the smooth sliced surface of the sheet between a heat generating body and a heat dissipator.
US Pat. No. 10,338,468

PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAMINATE, RESIN PATTERN PRODUCTION METHOD, CURED FILM, AND DISPLAY DEVICE

ASAHI KASEI KABUSHIKI KAI...

1. A photosensitive resin laminate comprising a support film, and a photosensitive resin layer including:(A) an alkali-soluble polymer;
(B) a compound having an ethylenic unsaturated double bond; and
(C) a photopolymerization initiator;
wherein the photosensitive resin layer is laminated on the support film,
the photosensitive resin laminate is to be used to form a protective film for a conductor component,
the thickness of the photosensitive resin layer is less than or equal to 20 ?m, and
a cured product of the photosensitive resin layer satisfies the following conditions (1) to (3):
(1) a crosslink density of 1,000 mol/m3 to 8,000 mol/m3;
(2) a Tan ? peak top value of 0.4 or greater; and
(3) a refractive index of 1.50 to 1.60 at a wavelength of 532 nm.
US Pat. No. 10,340,526

NONAQUEOUS LITHIUM-TYPE POWER STORAGE ELEMENT

Asahi Kasei Kabushiki Kai...

1. A nonaqueous lithium-type storage element, comprising a positive electrode containing a lithium compound other than a positive electrode active material, a negative electrode, a separator, and a nonaqueous electrolytic solution containing lithium ions,wherein the positive electrode comprises a positive electrode power collector, and a positive electrode active material layer located at one surface or both surfaces of the positive electrode power collector, and containing the positive electrode active material,
the negative electrode comprises a negative electrode power collector, and a negative electrode active material layer located at one surface or both surfaces of the negative electrode power collector, and containing the negative electrode active material,
2?C?300, where C (ppm) is concentration of Na and/or K element, contained in the positive electrode active material layer, and
1.0?D?15, 10?E?100, 0.2?C/D?38, and 0.1?C/E?7.2, where D (g/m2) is basis weight of the lithium compound other than the positive electrode active material, contained in the positive electrode active material layer, per one surface of the positive electrode, and E (g/m2) is basis weight of the positive electrode active material contained in the positive electrode active material layer, per one surface of the positive electrode.
US Pat. No. 10,336,685

CRYSTALLINE MODIFICATION OF PROPANIL

UPL LIMITED, Mumbai (IN)...


US Pat. No. 10,340,030

SYSTEMS AND METHODS FOR IDENTIFYING CANCER TREATMENTS FROM NORMALIZED BIOMARKER SCORES

BostonGene Corporation, ...

1. A system, comprising:at least one computer hardware processor;
at least one database that stores biomarker information; and
at least one non-transitory computer-readable storage medium storing processor-executable instructions that, when executed by the at least one computer hardware processor, cause the at least one computer hardware processor to perform:
obtaining sequencing data about at least one biological sample of a subject known to have or suspected of having cancerous cells or pre-cancerous cells;
accessing, in the at least one database, biomarker information indicating a distribution of values for each biomarker in at least a reference subset of a plurality of biomarkers across a respective group of people, each of the plurality of biomarkers being associated with at least one therapy in a plurality of therapies, the plurality of biomarkers including a first biomarker and the biomarker information including a distribution of values for the first biomarker;
determining, using both the sequencing data and the biomarker information:
a first set of normalized scores for a first set of biomarkers associated with a first therapy in the plurality of therapies,
a second set of normalized scores for a second set of biomarkers associated with a second therapy in the plurality of therapies, and
a third set of normalized scores for a third set of biomarkers associated with a third therapy in the plurality of therapies, wherein the first set of biomarkers is different from the second set of biomarkers, and wherein determining the first set of normalized scores comprises determining a first normalized score for the first biomarker using the distribution of values for the first biomarker at least in part by:
determining an un-normalized score for the first biomarker using the sequencing data,
determining a Z-score based on the first distribution of values for the first biomarker, and
determining a normalized score for the first biomarker based on the un-normalized score and the Z-score;
determining, using the first, second, and third sets of normalized scores and a statistical model, respective first, second, and third therapy scores for the first, second, and third therapies;
generating a graphical user interface (GUI), wherein the GUI comprises:
a first portion associated with the first therapy in the plurality of therapies, the first portion including a first plurality of GUI elements, each of the first plurality of GUI elements being associated with a respective biomarker in the first set of biomarkers and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the first set of normalized scores;
a second portion associated with the second therapy in the plurality of therapies, the second portion including a second plurality of GUI elements different from the first plurality of GUI elements, each of the second plurality of GUI elements being associated with a respective biomarker in the second set of biomarkers and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the second set of normalized scores; and
a third portion associated with the third therapy in the plurality of therapies, the third portion including a third plurality of GUI elements, each of the third plurality of GUI elements being associated with a respective biomarker in the third set of biomarkers and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the third set of normalized scores; and
displaying the generated GUI.
US Pat. No. 10,340,031

SYSTEMS AND METHODS FOR IDENTIFYING CANCER TREATMENTS FROM NORMALIZED BIOMARKER SCORES

BostonGene Corporation, ...

1. A system, comprising:at least one computer hardware processor;
at least one database that stores biomarker information; and
at least one non-transitory computer-readable storage medium storing processor-executable instructions that, when executed by the at least one computer hardware processor, cause the at least one computer hardware processor to perform:
obtaining sequencing data about at least one biological sample of a subject known to have or suspected of having cancerous cells or pre-cancerous cells;
accessing, in the at least one database, biomarker information indicating a distribution of values for each biomarker, across a respective group of people, in at least a reference subset of the plurality of biomarkers, each of the plurality of biomarkers being associated with at least one therapy in a plurality of therapies, the plurality of biomarkers including a first biomarker and the biomarker information including a distribution of values for the first biomarker;
determining, using both the sequencing data and the biomarker information:
a first set of normalized biomarker scores for a first set of biomarkers associated with a first therapy in the plurality of therapies,
a second set of normalized biomarker scores for a second set of biomarkers associated with a second therapy in the plurality of therapies, and
a third set of normalized biomarker scores for a third set of biomarkers associated with a third therapy in the plurality of therapies,
wherein the first set of biomarkers is different from the second set of biomarkers, and wherein determining the first set of normalized biomarker scores comprises determining a first normalized biomarker score for the first biomarker using the distribution of values for the first biomarker at least in part by:
determining an un-normalized score for the first biomarker using the sequencing data,
determining a Z-score based on the first distribution of values for the first biomarker, and
determining a normalized score for the first biomarker based on the un-normalized score and the Z-score; and
determining, using the first, second, and third sets of normalized biomarker scores and a statistical model, respective first, second, and third therapy scores for the first, second and third therapies;
wherein the plurality of therapies comprise at least three therapies selected from the group consisting of: an anti-PD1 therapy, an anti-CTLA4 therapy, an IL-2 therapy, an IFN alpha therapy, an anti-cancer vaccine therapy, an anti-angiogenic therapy, and an anti-CD20 therapy, and
wherein the first, second, and third sets of biomarkers associated with the first, second and third each comprises at least three biomarkers selected from the group of biomarkers associated with the respective therapy in Table 2.
US Pat. No. 10,336,711

PROLYL HYDROXYLASE INHIBITORS

GlaxoSmithKline LLC, Wil...

1. A method of treating anemia associated with cancer in a human which comprises administering to such human N-[(1,3-dicyclohexyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)carbonyl]glycine, or a pharmaceutically acceptable salt thereof.
US Pat. No. 10,339,274

VIRAL NEOEPITOPES AND USES THEREOF

NANTOMICS, LLC, Culver C...

1. A method of treating a patient having a virus-associated tumor, comprising:obtaining a biopsy sample from the virus-associated tumor of the patient and analyzing the biopsy sample to identify a non-patient nucleic acid in the virus-associated tumor;
determining a plurality of nucleic acid sequences encoding patient-specific and tumor-specific neoepitopes for the virus-associated tumor by identifying overlaps between the non-patient nucleic acid and a reference nucleic acid of a virus known to be related to the virus-associated tumor, wherein each of the neoepitopes has a length of between 5 and 30 amino acids, and wherein the non-patient nucleic acid includes a mutation compared to the reference nucleic acid of the virus related to the virus-associated tumor, and wherein the mutation occurs upon insertion of the non-patient nucleic acid into a patient's host genome;
identifying an HLA-matched neoepitope from the plurality of patient-specific and tumor-specific neoepitopes, wherein the HLA-matched neoepitope includes the non-patient nucleic acid, includes the mutation, and has a dissociation constant equal to or less than 100 nM with an HLA-type of the patient; and
administering to the patient having the virus-associated tumor an immunotherapeutic composition comprising a recombinant virus that includes the nucleic acid encoding the HLA-matched neoepitope or a recombinant cell expressing a recombinant protein that targets the HLA-matched neoepitope, thereby triggering an immune response against the HLA-matched neoepitope of the virus-associated tumor.
US Pat. No. 10,335,442

METHOD FOR TOPICAL TREATMENT OF NAIL CONDITIONS

Marlinz Pharma, LLC, Hou...

1. A method of treating discoloration of nails, comprising: topically applying to said nails a composition comprising:from about 2 to about 15% by weight of a urea-based component;
from about 10 to about 55% by weight of a monohydric alcohol containing 2 to 4 carbon atoms;
from about 8 to about 20% by weight dimethyl isosorbide;
from about 15 to about 30% by weight of undecylenic acid;
from about 10 to about 25% by weight of a carboxylic acid component other than undecylenic acid; and
from about 4 to about 15% by weight of a diol containing 2 to 4 carbon atoms.
US Pat. No. 10,335,443

ORODISPERSIBLE FILM

HEXAL AG, Holzkirchen (D...

1. An orodispersible film consisting essentially of:a) a plant extract selected from the group consisting of a hedera helix leaf extract, a coptidis rhizoma extract, a primula veris extract, a primula elatior extract, and a thymus vulgaris extract or a mixture thereof;
b) hydroxypropyl methyl cellulose;
c) microcrystalline cellulose;
d) glycerol; and
e) maltodextrin, wherein said orodispersible film rapidly disintegrates in the oral cavity of a patient in less than 20 seconds.
US Pat. No. 10,336,982

TARGETED MUTAGENESIS IN SPIRULINA

LUMEN BIOSCIENCE, INC., ...

1. A non-naturally occurring, stable transformant Arthrospira cell, comprising:a. an introduced targeted nucleotide mutation incorporated into the cell's genome,
wherein the introduced targeted nucleotide mutation is flanked on each side by a region of nucleotides that are homologous to nucleotide homology arms contained in a vector utilized to transform said cell and wherein the introduced targeted nucleotide mutation is stable for at least 50 generations.
US Pat. No. 10,336,984

METHOD OF MOLECULAR STRESS CONTROL

CPSI Holdings LLC, Owego...

1. A cell selection method comprising the steps of:applying a cell selection reagent to an in vitro heterogeneous population of cells, wherein the heterogeneous population of cells includes at least a first population of cancerous mammalian hepatic cells and a second population of non-cancerous mammalian hepatic cells, and the cell selection reagent is an unfolded protein response (UPR) pathway inhibitor or a UPR pathway inducer; and
exposing the heterogeneous population of cells to a stress regimen, wherein the stress regimen produces a cell-type specific stress response in the heterogeneous population of cells, and wherein the cell selection reagent selectively modulates the UPR pathway in a cell-type specific manner in one of the first population of cancerous hepatic cells or the second population of non-cancerous hepatic cells to confer protection from the stress regimen,
wherein the cell selection method is performed according to one of the following sets of parameters:
a) the cell selection reagent is salubrinal, the stress regimen includes a hypothermic condition, and the selective modulating extends viability of the first population of cancerous mammalian hepatic cells, or
b) the cell selection reagent is resveratrol (FR-48), the stress regimen includes a hypothermic condition, and the selective modulating extends viability of the second population of non-cancerous mammalian hepatic cells, or
c) wherein the cell selection reagent is salubrinal, the stress regimen includes hypoxic, normothermic storage, and the selective modulating extends viability of the second population of non-cancerous mammalian hepatic cells.
US Pat. No. 10,336,986

CELL CULTURING ARTICLE AND METHOD FOR MANUFACTURING THEREOF

National Central Universi...

1. A cell culturing article, comprising:a base layer having a surface;
a hydrophilic copolymer layer positioned on the base layer, wherein the hydrophilic copolymer layer comprises a plurality of polyvinyl alcohol units, a plurality of polyvinyl alcohol derivative units and a plurality of itaconic acid units, the itaconic acid units comprise a plurality of carboxyl groups; and
a plurality of peptide chains individually conjugated on a surface of the hydrophilic copolymer layer, and at least one amino group of each of the peptide chains reacting with one of the carboxyl groups of the itaconic acid units to form an amide bond.
US Pat. No. 10,335,454

COMBINATION AND USE

HELPERBY THERAPEUTICS LIM...

1. A combination comprising suloctidil or a pharmaceutically acceptable derivative or prodrug thereof, and a polymyxin selected from polymyxin E and polymyxin B or a pharmaceutically acceptable derivative thereof.
US Pat. No. 10,336,992

METHODS FOR PURIFICATION OF ARYLSULFATASE A

Shire Human Genetic Thera...

1. A method of purifying recombinant arylsulfatase A (ASA) protein, comprisingproviding a sample of recombinant ASA protein;
subjecting the sample to a first chromatography step which is anion exchange chromatography,
subjecting the sample from the anion exchange chromatography to a second chromatography step which is mixed-mode chromatography,
subjecting the sample from the mixed-mode chromatography to a third chromatography step which is hydrophobic interaction chromatography, and
subjecting the sample from the hydrophobic interaction chromatography to a fourth chromatography step which is cation exchange chromatography,
wherein fractions from each chromatography step containing recombinant ASA protein are determined by detecting the presence of recombinant ASA protein or enzymatic activity, and
wherein the purified recombinant ASA protein has a specific activity of at least 75 U/mg,
wherein 1 Unit of enzyme activity is defined as the hydrolysis of 1 ?mol p-Nitrocatechol Sulphate (pNCS) per minute at 37° C., pH 5.0.
US Pat. No. 10,335,460

IL-15 AND IL-15R? HETERODIMER DOSE ESCALATION REGIMENS FOR TREATING CONDITIONS

NOVARTIS AG, Basel (CH) ...

1. A method for treating lymphocytopenia, cancer or an infectious disease in a human subject, comprising:(a) administering an initial low dose of a human IL-15/IL-15R? complex to the human subject, wherein the initial low dose is between 0.1 ?g/kg and 1 ?g/kg as determined based on the mass of single chain IL-15;
(b) obtaining a plasma sample taken from a human subject; and
(c) detecting a concentration of free IL-15 of 1 pg/ml to 50 pg/ml in the sample obtained from the subject after the administration of the initial low dose of the human IL-15/IL-15R? complex and administration of successively higher doses of the human IL-15/IL-15R? complex, wherein each successively higher dose is from two to three times higher than the previous dose.
US Pat. No. 10,335,461

INTERFERON THERAPY

Trizell Limited, Chinnor...

1. A method of treating a human patient with interferon comprising:a. diagnosing in a human patient a cancer which may be treated with interferon, and then
b. administering to the human patient interferon or an agent which induces interferon in a therapeutically effective amount, wherein interferon up-regulates programmed death protein ligand (PD-L1), and
c. administering to the human a monoclonal antibody against programmed cell death protein 1, the monoclonal antibody against programmed cell death protein 1 administered in an amount effective to ameliorate the decrease in T cell function which interferon would cause,whereby the monoclonal antibody against programmed cell death protein 1 ameliorates the decrease in T cell function caused by interferon.
US Pat. No. 10,336,744

1AP E3 LIGASE DIRECTED PROTEOLYSIS TARGETING CHIMERIC MOLECULES

GlaxoSmithKline Intellect...

1. A compound selected from the group consisting of(S)-7-(2-(2-(2-(2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinolin-7-yl)oxy)ethoxy)ethoxy)ethoxy)ethoxy)-2-((S)-3,3-dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-N—((R)-1,2,3,4-tetrahydronaphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide,
(S)-7-(2-(2-(2-(2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinolin-7-yl)oxy)ethoxy)ethoxy)ethoxy)ethoxy)-2-((S)-3,3-dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-N—((S)-1,2,3,4-tetrahydronaphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide,
(S)-2-((S)-3,3-Dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-7-(2-(2-(2-(2-(4-((6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)oxy)phenoxy)ethoxy)ethoxy)ethoxy)ethoxy)-N—((R)-1,2,3,4-tetrahydronaphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, and
(2S,4S)-4-(14-(4-(4-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-4-oxobutyl)piperazin-1-yl)-3,6,9,12-tetraoxatetradecanamido)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N—((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide,or a pharmaceutically acceptable salt thereof.
US Pat. No. 10,337,000

EXPRESSION VECTOR PRODUCTION AND HIGH-THROUGHPUT CELL SCREENING

KYMAB LIMITED, Cambridge...

1. A method of producing cells encoding a repertoire of antibody binding sites comprising a VH sequence and VL sequence, the method comprising:a) providing a population of cells expressing a repertoire of antibody binding sites, which cells are isolated from one or more animals and which comprise B cells, germinal center cells, memory B cells, antibody-secreting cells, plasma cells, or plasmablast cells;
b) sorting the population of cells by binding the antibody binding sites to an antigen of interest to produce a sorted population of single cells, each cell comprising nucleic acid encoding a respective antibody binding site, and each sorted cell provided in a separate container;
c) amplifying the nucleic acid comprised by the sorted single cell population using PCR to produce a sorted repertoire of amplified nucleic acids encoding antibody binding sites, wherein the VH and VL sequences of each antibody binding site are amplified in the same container;
d) modifying the sorted amplified antibody binding site-encoding nucleic acids from step (c) to produce a sorted repertoire of expression cassettes, each container comprising a first type of cassette comprising a nucleotide sequence encoding a VH sequence of an antibody binding site and one or more regulatory elements for expressing the VH sequence of the antibody binding site from said single cell, and a second type of cassette comprising a nucleotide sequence encoding a VL sequence of an antibody binding site and one or more regulatory elements for expressing the VL sequence of the antibody binding site from said single cell, wherein the VH and VL sequences of each antibody binding site are modified in the same container; and
e) transferring the antibody binding site expression cassettes from said cassette repertoire to a sorted population of host cells while maintaining the antibody binding site expression cassette sorting and producing a sorted repertoire of host cells that expresses a sorted repertoire of antibody binding sites, wherein the sorted repertoire of host cells is capable of stably expressing the repertoire of antibody binding sites.
US Pat. No. 10,337,007

OLIGOMERIC COMPOUNDS COMPRISING BICYCLIC NUCLEOTIDES AND USES THEREOF

Ionis Pharmaceuticals, In...

1. A compound comprising:a modified oligonucleotide consisting of 16 to 20 linked nucleosides, wherein the modified oligonucleotide comprises a sugar motif of e-k-k-(D)9-k-e-k-e, wherein each “k” comprises a bicyclic nucleoside, each “e” comprises a 2?-substituted nucleoside, and each “D” comprises a 2?-deoxynucleoside; and wherein each 2?-substituent is selected from among: 2?-OMe, 2?-O-methoxyethyl, and 2?-F; and wherein the nucleobase sequence of the modified oligonucleotide is complementary to the nucleobase sequence of a target nucleic acid.
US Pat. No. 10,335,472

THERAPEUTIC CANCER VACCINE

Cadila Pharmaceuticals Lt...

1. A method for inducing an anticancer immune response in a mammalian subject having a cancer, said method comprising harvesting cancer cells cultured in vitro, washing the cells to remove traces of serum, culturing the cancer cells in vitro in the presence of Mycobacterium w. for a period of time sufficient to induce the expression by the cancer cells of p38, separating the cancer cells from the Mycobacterium w. cells by centrifugation, measuring the level of p38 expression in the cancer cells, collecting cancer cells overexpressing p38 as compared to cancer cells not contacted with Mycobacterium w., irradiating or killing the cancer cells, and administering to the subject an effective amount of the irradiated or killed cancer cells overexpressing p38 to induce an anticancer immune response.
US Pat. No. 10,337,010

ANGIOPOIETIN-LIKE 3 (ANGPTL3) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

Alnylam Pharmaceuticals, ...

1. A double-stranded ribonucleic acid (dsRNA) agent for inhibiting expression of Angiopoietin-like 3 (ANGPTL3), wherein said dsRNA agent comprises a sense strand and an antisense strand forming a double stranded region, the antisense strand comprising a region of complementarity to an mRNA encoding ANGPTL3 which comprises at least 15 contiguous nucleotides differing by no more than 3 nucleotides from the complement of nucleotides 1051-1098 of SEQ ID NO:1.
US Pat. No. 10,338,042

APPARATUS AND METHOD FOR INVESTIGATING DISCONTINUOUS PRODUCT FLUID STREAMS IN THE REACTION OF REACTANT FLUID STREAMS OVER SOLID CATALYSTS

hte GmbH the high through...

1. An apparatus suitable for investigating solid catalysts and processes in which discontinuous fluid streams arise, the apparatus comprising:a reactant fluid supply point;
at least one reaction space;
at least one fluid mixing space;
at least one throttle element;
at least one pressure control valve; and
at least one analyzer,
wherein an outlet side of the at least one reaction space is connected to a connecting line, and an end of the connecting line is separated into a substream line and an exit line such that the outlet side of the at least one reaction space is operatively connected to the at least one fluid mixing space via the connecting line and the substream line and to an exit air line via the connecting line and the exit line,
the at least one fluid mixing space is connected to the at least one throttle element,
the at least one throttle element is operatively connected to the at least one analyzer and an outlet line,
the connecting line is operatively connected to the at least one pressure control valve and the exit air line, and
the at least one pressure control valve is arranged either downstream or upstream of the substream line and, when the at least one pressure control valve is upstream of the substream line, the outlet line is provided with a second pressure control valve and a pump.
US Pat. No. 10,335,761

METHOD OF MANUFACTURING BIO-DIESEL AND REACTOR

Louisiana Eco Green, L.L....

1. A method of forming bio-diesel comprising:emulsifying a mixture comprising water, alcohol and a source of fatty acids, wherein said alcohol comprises between about 7 and about 16 percent, by weight, of the mixture;
pressurizing and heating said emulsion until said alcohol is super-critical;
pumping said emulsion through a vessel under substantially non-laminar flow;
maintaining said substantially non-laminar flow of said emulsion and said super-criticality of said alcohol in said emulsion for at least about 1.5 minutes.
US Pat. No. 10,337,042

METHOD FOR PRODUCING GALACTOOLIGOSACCHARIDES FROM LACTOSE

Vitalus Nutrition Inc., ...

1. A galactooligosaccharide (GOS) composition comprising:galactose;
glucose;
?-D-Galp-(1?3)-D-Galp;
?-D-Galp-(1?6)-D-Galp;
?-D-Galp-(1?3)-D-Glcp;
?-D-Galp-(1?4)-D-Glcp;
?-D-Galp-(1?6)-?-D-Galp-(1?4)-D-Glcp;
?-D-Galp-(1?2)-D-Glcp;
?-D-Galp-(1?3)-DGlcp;
?-D-Galp-(1?4)-?-D-Galp-(1?4)-D-Glcp;
?-D-Galp-(1?3)-?-D-Galp-(1?4)-D-Glcp;
?-D-Galp-(1?6)-?-D-Galp-(1?6)-?-D-Galp-(1?4)-D-Glcp;
?-D-Galp-(1?6)-?-D-Galp-(1?3)-?-D-Galp-(1?4)-D-Glcp; and
?-D-Galp-(1?6)-?-D-Galp-(1?4)-?-D-Galp-(1?4)-D-Glcp.
US Pat. No. 10,336,791

MEANS AND METHODS FOR MEDIATING PROTEIN INTERFERENCE

VIB VZW, Ghent (BE) VRIJ...

1. A non-naturally occurring molecule down-regulating the biological function of a target protein, comprising a beta-aggregation region fused to a moiety,wherein the beta-aggregation region consists of at least 6 contiguous amino acids,
wherein the moiety is a peptide or a protein domain,
wherein the non-naturally occurring molecule has a specificity for the target protein, and
wherein the non-naturally occurring molecule is obtained by the steps comprising:
i) acquiring the amino acid sequence of said target protein;
ii) determining an aggregation propensity score and identifying a beta-aggregation region within the amino acid sequence of said target protein;
iii) isolating the beta-aggregation region from the amino acid encoding sequence of said target protein; and
iv) covalently linking the isolated beta-aggregation region to a moiety to obtain said non-naturally occurring molecule, wherein said peptide or protein domain is not present in the target protein.
US Pat. No. 10,338,076

METHODS AND COMPOSITIONS FOR THE DIAGNOSIS OF OVARIAN CANCER

The Wistar Institute of A...

1. A method for diagnosing or detecting or monitoring the progress or treatment of ovarian cancer in a subject comprising:contacting a sample obtained from a test subject with a diagnostic reagent consisting of
(a) a ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker chloride intracellular channel protein 4 (CLIC4) or an isoform, pro-form, modified molecular form, posttranslational modification, or unique peptide fragment or unique nucleic acid fragment thereof;
(b) a ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker chloride intracellular channel protein 1 (CLIC1) or an isoform, pro-form, modified molecular form, posttranslational modification, or unique peptide fragment or unique nucleic acid fragment thereof; and
(c) a ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker cathepsin D-30 (CTSD-30) or an isoform, pro-form, modified molecular form, posttranslational modification, or unique peptide fragment or unique nucleic acid fragment thereof; and
one or more additional ligands, each additional ligand capable of specifically complexing with, binding to, or quantitatively detecting, or identifying an additional biomarker that indicates the presence of ovarian cancer in a human subject, wherein said additional biomarker is selected from:
i. tropomyosin 1 (TPM1);
ii. tropomyosin 2 (TPM2);
iii. tropomyosin 3 (TPM3);
iv. tropomyosin 4 (TPM4);
v. proteasome subunit alpha type-7 (PSMA7)
vi. CA125; and
vii. HE4,
(ii) detecting or measuring in the sample or from a protein level profile generated from the sample, the protein levels of the selected biomarkers;
(iii) comparing the protein level of the selected biomarkers in the subject's sample with the level of the same biomarkers in a reference standard;
wherein a significant change in the protein level of one or more of the selected biomarkers in the subject's sample from that in the reference standard indicates a diagnosis, risk, or the status of progression or remission of ovarian cancer in the subject.
US Pat. No. 10,335,517

POROUS POLYMER MATERIAL, PREPARATION METHOD THEREFOR, AND BIOMATERIAL USING SAME

Dankook University Cheona...

1. A porous polymer material having a porous structure over a surface and an inside of the polymer material,wherein the porous structure includes a plurality of first pores formed over the surface of the polymer material, a plurality of second pores in the form of column pores and formed up to a certain distance from the surface of the polymer material, and a plurality of third pores connected to each other and disposed under the plurality of second pores,
wherein the porous polymer material may be in the form of particles, and an average particle size of the particles is 10 to 3000 ?m.
US Pat. No. 10,338,082

METHODS FOR IN VITRO INVESTIGATING MITOCHONDRIAL REPLICATION DYSFUNCTION IN A BIOLOGICAL SAMPLE, KITS AND USES THEREOF, THERAPEUTIC METHODS AGAINST PROGEROID-LIKE SYNDROMES OR SYMPTOMES AND SCREENING METHOD FOR IDENTIFYING PARTICULAR PROTEASE INHIBITOR(S)

INSTITUT PASTEUR, Paris ...

1. An in vitro method to detect a protein in a sample from a subject suspected of having Cockayne syndrome (CS), comprising:a) providing at least one sample from a subject suspected of having CS; and
b) detecting in said sample at least one protein selected from the group consisting of: POLG1, POLG2, HTRA3, and HTRA2.
US Pat. No. 10,336,810

CHIMERIC ANTIGEN RECEPTORS, ENCODING NUCLEIC ACIDS AND METHODS OF USE THEREOF

University Health Network...

1. A chimeric antigen receptor (CAR) comprising i) an extracellular domain capable of binding to a predetermined antigen, ii) a transmembrane domain and iii) an intracellular segment comprising a) one or more intracellular signaling domains selected from a cytoplasmic domain of an interleukin receptor chain and a cytoplasmic co-stimulatory domain and b) a CD3? intracellular signaling domain comprising an exogenous Signal Transducer and Activator of Transcription (STAT) 3 association motif, wherein the intracellular segment comprises an endogenous or exogenous JAK-binding motif and a STAT5 association motif.
US Pat. No. 10,336,843

ULTRA-HIGH MOLECULAR WEIGHT ETHYLENE-BASED COPOLYMER POWDER, AND MOLDED ARTICLE USING ULTRA-HIGH MOLECULAR WEIGHT ETHYLENE-BASED COPOLYMER POWDER

Asahi Kasei Kabushiki Kai...

1. An ultra-high molecular weight ethylene-based copolymer powder comprising:an ethylene unit and an ?-olefin unit having 3 or more and 8 or less carbon atoms as structural units,
wherein the ultra-high molecular weight ethylene-based copolymer powder has a viscosity-average molecular weight of 100,000 or more and 10,000,000 or less,
a content of the ?-olefin unit is 0.01 mol % or more and 0.10 mol % or less based on a total amount of the ethylene unit and the ?-olefin unit, and
in measurement with a differential scanning calorimeter under following conditions, an isothermal crystallization time is determined as a time from reaching 126° C. of Step A3 as a starting point (0 min) to giving an exothermic peak top due to crystallization and the isothermal crystallization time is 5 minutes or more (Conditions for measurement of isothermal crystallization time);
Step A1: holding at 50° C. for 1 minute and then an increase up to 180° C. at a temperature rise rate of 10° C./min,
Step A2: holding at 180° C. for 30 minutes and then a decrease down to 126° C. at a temperature drop rate of 80° C./min, and
Step A3: holding at 126° C.
US Pat. No. 10,335,841

METHOD OF FORMING AN AL—MG ALLOY PLATE PRODUCT

ALERIS ROLLED PRODUCTS GE...

1. A method of obtaining a predetermined two- or three-dimensional formed structure of an AlMg alloy plate product, comprising the steps of:providing an alloy plate having a gauge of at least 10 mm and a chemical composition, in wt. %:
Mg 2.5% to 6%,
Mn 0 to 1.2%,
Sc 0 to 1%,
Ag 0 to 0.5%,
Zn 0 to 2%,
Cu 0 to 2%,
Li 0 to 3%,
optionally at least one or more elements selected from the group consisting of Zr 0.03% to 0.4%, Cr 0.03% to 0.4%, and Ti 0.005% to 0.3%,
optionally one or more elements selected from the group of Er, Dy, Gd, and Hf in a total amount of 0.03% to 0.3%,
Fe 0 to 0.4%,
Si 0 to 0.25%,
inevitable impurities and balance aluminium;
shaping or forming the alloy plate at a temperature in a range of 200° C. to 400° C. to obtain the predetermined two- or three-dimensional formed structure; and
heat treating the predetermined two- or three-dimensional formed structure.
US Pat. No. 10,336,884

BLOCK COPOLYMERS FOR GEL COMPOSITIONS

Kraton Corporation, Hous...

1. A composition comprisingi) a hydrogenated styrenic block copolymer having a peak molecular weight of from 125 to 300 kg/mol, wherein said hydrogenated styrenic block copolymer is a diblock copolymer of formula S-EB;
wherein S is a polymer block of a monoalkenyl arene, and EB is a hydrogenated polymer block of 1,3-butadiene;
ii) an oil; and
iii) optionally one or more additives;
wherein the composition forms a gel having a thixotropic ratio at 25° C. of from 5 to 10.
US Pat. No. 10,336,899

POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION

WinTech Polymer Ltd., To...

7. A method of making a polybutylene terephthalate resin composition with an increased comparative tracking index measured in accordance with a third edition of IEC 60112, the method comprising combining a polybutylene terephthalate resin, glass fiber, an epoxy compound having an epoxy equivalent weight of 600 to 1,500 g/equivalent, and an ethylene/ethyl acrylate copolymer to form the polybutylene terephthalate resin composition; wherein the polybutylene terephthalate resin composition consists of said polybutylene terephthalate resin, said glass fiber, said epoxy compound, and said ethylene/ethyl acrylate copolymer; wherein the glass fiber is present in an amount of 10 to 20% by mass relative to a total mass of the polybutylene terephthalate resin composition; andwherein the polybutylene terephthalate resin composition has a comparative tracking index of 600 V or higher.
US Pat. No. 10,338,184

MONITORING METHODS AND SYSTEMS FOR PROCESSING BIOMASS

XYLECO, INC., Wakefield,...

1. A method comprising:irradiating a plurality of biomass portions, each portion being irradiated to a dose;
measuring an ESR response associated with each portion to produce a first curve of response versus dosage;
determining a saturation dose for the biomass from the first curve of response versus dosage;
heating the plurality of irradiated biomass portions for a predetermined time at a temperature above 50 degrees C. to produce a plurality of heat-treated biomass portions; and
measuring an ESR response associated with each heat-treated biomass portion to produce a second curve of response versus dosage.

US Pat. No. 10,342,101

LIGHT SOCKET WIFI DEVICE

CenturyLink Intellectual ...

1. A device, comprising:a light socket attachment that mates with a light socket receptacle of a lighting device when the light socket attachment is removably coupled to the lighting device, wherein the light socket receptacle of the lighting device is a three-terminal power connection light socket receptacle;
a communications system comprising a non-wired communications device;
a wired communications adapter contained within the communications system, wherein the wired communications adapter provides a link between the communications system and the light socket receptacle, and wherein the wired communications adapter is configured to transmit or receive data via the three terminals of the three-terminal power connection light socket, wherein a first terminal and a second terminal of the three terminal power connection light socket transmit data to the communications system, wherein a third terminal separate from the first terminal and the second terminal of the three terminal power connection light socket receives data from the communications system;
a light bulb receptacle configured to receive a light bulb; and
circuitry that receives electric power through the light socket attachment, the circuitry directing a specified amount of power from the received electric power to the communications system while directing remaining power of the received electric power to the light bulb receptacle.

US Pat. No. 10,342,092

LIGHT SOURCE APPARATUS AND CONTROL METHOD THEREOF

Canon Kabushiki Kaisha, ...

1. A light source apparatus, comprising:a light source unit; and
a control unit configured to perform lighting control to light the light source unit, wherein
the light source unit emits first color light at a first timing, and emits second color light at a second timing which delays after the first timing by a predetermined period, in accordance with the lighting control by the control unit, and
the control unit performs a plurality of times of lighting control based on the predetermined period, so that at least a part of a period in which the light source unit emits the second color light in accordance with a first lighting control overlaps with at least a part of a period, in which the light source unit emits the first color light in accordance with a second lighting control, which is performed after the first lighting control.

US Pat. No. 10,341,996

USER APPARATUS AND UPLINK CONTROL INFORMATION BIT WIDTH DETERMINATION METHOD

NTT DOCOMO, INC., Tokyo ...

1. A user apparatus configured to perform communication with a base station in a mobile communication system that supports downlink spatial multiplexing, comprising:a transmitter that transmits capability information of the user apparatus to the base station, wherein the capability information comprises a user equipment category and a number of supported MIMO layers for a specific transmission mode;
a receiver that receives configuration information from the base station, wherein the configuration information comprises:
a parameter indicating a transmission mode corresponding to the downlink spatial multiplexing and
predetermined additional information; and
a processor that determines a bit width of a rank indicator based on the predetermined additional information,
wherein before determining the bit width of the rank indicator, the user apparatus determines whether the predetermined additional information is a maximum number of MIMO layers transmitted from the base station as information to be used for determining a bit width of the rank indicator.

US Pat. No. 10,341,991

DYNAMIC UPLINK/DOWNLINK SUBFRAME CONFIGURATION

TELEFONAKTIEBOLAGET LM ER...

1. An apparatus for an uplink (UL) and downlink (DL) subframe configuration in a radio access network, comprising:a memory configured to store an information on a UL data and a DL data; and
a processor configured to:
obtain a UL throughput and a DL throughput based on the information, wherein the UL throughput is obtained based on calculating an average UL transport block (TB) size per each UL subframe received during a previous time division duplex (TDD) window, and the DL throughput is obtained based on calculating an average TB size per each DL subframe transmitted during the previous TDD window,
estimate a UL buffer size responsive to a determination that a UL buffer size obtained from a most recently received buffer status report (BSR) is obsolete,
calculate a UL and DL subframe allocation ratio indicative of numbers of UL and DL subframes to be allocated to a TDD window based on the estimated UL buffer size, a DL buffer size, the UL throughput and the DL throughput, and
determine the UL and DL subframe configuration based on the UL and DL subframe allocation ratio.

US Pat. No. 10,341,986

METHOD FOR TRANSMITTING A PAGING MESSAGE TO A TERMINAL USING A VIRTUAL NETWORK NODE

NEC CORPORATION, Minato-...

7. A control device comprising:first unit that receives a packet addressed to a terminal that, in response to receiving a paging message, is able to establish a session with a communication device of a network; and
second unit that, in response to receiving a packet addressed to the terminal, requests at least one of a plurality of virtual network nodes to transmit the paging message addressed to the terminal, each of the plurality of virtual network nodes being able to run, on a virtual machine, a function of processing a control signal from the terminal.

US Pat. No. 10,341,983

LOCATING CUSTOMER PREMISES EQUIPMENT IN A NARROW BEAMWIDTH BASED RADIO ACCESS NETWORK

Verizon Patent and Licens...

1. A method, comprising:receiving, by a base station and from a customer premises equipment, information that identifies a position of the customer premises equipment;
providing, by the base station and to the customer premises equipment, first wireless signals in association with a first radiation pattern;
receiving, by the base station, first information associated with a first network metric value,
the customer premises equipment to determine the first network metric value based on the first wireless signals;
adjusting, by the base station and based on the first network metric value, a direction of a lobe of the first radiation pattern;
receiving, by the base station and based on adjusting the direction of the lobe of the first radiation pattern, second information associated with a second network metric value;
determining, by the base station, that the second network metric value satisfies a threshold;
providing, by the base station and based on the second network metric value satisfying the threshold, second wireless signals in association with a second radiation pattern; and
narrowing, by the base station, a lobe of the second radiation pattern.

US Pat. No. 10,341,971

METHOD AND APPARATUS FOR RADIO INTERFACE-BASED INTER-CELL SYNCHRONIZATION IN WIRELESS COMMUNICATION SYSTEM

LG ELECTRONICS INC., Seo...

1. A method performed by a small cell in a wireless communication system, the method comprising:receiving a first maximum stratum level, indicating a maximum value of a hop capable of supporting radio interface based synchronization (RIBS), from an evolved NodeB (eNB) having a global positioning system (GPS);
transmitting information indicating that a stratum level of the small cell is greater than the first maximum stratum level to the eNB, when the stratum level of the small cell is greater than the first maximum stratum level; and
receiving a second maximum stratum level from the eNB,
wherein the second maximum stratum level is determined by the eNB based on a ratio of small cells having stratum level greater than the first maximum stratum level, and
wherein the information further includes a cause for the greater small cell stratum level.

US Pat. No. 10,341,956

OPPORTUNISTIC RX CHAIN DEPOWERING BASED ON ALLOCATED RANK AND MCS

Apple Inc., Cupertino, C...

1. A method for a wireless user equipment (UE) device, the method comprising:establishing a wireless communication link;
receiving control information associated with the wireless communication link using a plurality of receiver chains;
constructing a look up table (LUT) comprising a plurality of entries, wherein each entry of the LUT comprises:
an active receiver chain set, and
an achievable code rate;
based on the control information, depowering a first subset of the plurality of receiver chains, wherein the first subset of the plurality of receiver chains is selected for depowering based on the LUT; and
receiving additional information through the wireless communication link using a second subset of the plurality of receiver chains, wherein the second subset of the plurality of receiver chains are not depowered.

US Pat. No. 10,341,953

LOW POWER PACKET DETECTION CIRCUIT FOR WLAN RECEIVERS

TEXAS INSTRUMENTS INCORPO...

1. A receiver comprising:a first channel configured to receive an RF signal and configured to generate an input signal;
a second channel configured to receive the RF signal; and
a packet detection circuit coupled to the first channel and the second channel, and configured to detect a valid packet in the input signal, and wherein the packet detection circuit is configured to activate the second channel on detection of the valid packet.

US Pat. No. 10,341,949

METHOD AND COMMUNICATION DEVICE OF BEACON RECEPTION

MEDIATEK INC., Hsinchu (...

1. A method of beacon reception for a communication device in a wireless communication system, the method comprising:starting to receive, by a communication circuit of the communication device, a beacon from an access point (AP) of the wireless communication system;
obtaining a specific element of the beacon from a received portion of the beacon;
determining, by a processing circuit of the communication device, whether to terminate receiving the beacon before reception thereof is completed according to the obtained specific element, including
when a first value of the specific element of the beacon is the same as a second value of a specific element of a previously received beacon,
determining to terminate receiving the beacon before the reception thereof is completed, except after the communication device having determined to terminate receiving other beacons, which include specific elements having values the same as the first value, before the completion thereof for a predetermined number of times, and
determining to receive an entirety of the beacon to avoid data loss after the communication device having determined to terminate receiving the other beacons, which include the specific elements having the values the same as the first value, before the completion thereof for the predetermined number of times; and
causing, by the processing circuit of the communication device, the communication circuit of the communication device to receive the entirety of the beacon or to terminate receiving the beacon before the reception thereof is completed according to a result of the determining whether to terminate receiving the beacon before the reception thereof is completed.

US Pat. No. 10,341,940

HIERARCHICAL ACCESS INFORMATION TABLES FOR CONTROLLING OF ACCESS TO A CELLULAR NETWORK

Telefonaktiebolaget LM Er...

1. A method of controlling access to a cellular network, the method comprising:an access node of the cellular network sending a first access information table in a broadcast transmission to a plurality of communication devices, the first access information table comprising a first group of entries, each entry of the first group indicating one or more parameters for controlling access of the plurality of communication devices to the cellular network and being mapped to an identifier from a first group of identifiers; and
the access node sending a second access information table in a unicast transmission to a communication device of the plurality of communication devices, the second access information table comprising a second group of entries, each entry of the second group indicating one or more parameters for controlling access of the communication device to the cellular network and being mapped to an identifier from a second group of identifiers,
wherein the one or more parameters for controlling access to the cellular network indicated by the first access information table and the second access information table relate to opportunities for performing a random access procedure.

US Pat. No. 10,341,932

METHODS, APPARATUS AND SYSTEMS FOR DETERMINING WHETHER TO INCLUDE AN ACCESS TRANSFER GATEWAY IN A CALL FLOW

Ribbon Communications Ope...

11. A method comprising:receiving, at a first processing node, a call setup message from a first user device to a second user device, said first processing node being a Session Border Controller;
making a first determination based at least in part on a geographical location indicator corresponding to the first user device whether to introduce into a call path between the first user device and the second user device an Access Transfer Gateway (ATGW);
controlling, by the first processing node, the introduction of the ATGW into the call path based upon the first determination, said first user device being a mobile device operating in a 4G network, said first determination being made by a fallback determination device, and said call setup message being a Session Initiation Protocol (SIP) INVITE message including a 4G network cell id corresponding to a 4G network cell in which the first user device is currently located;
transmitting, from said Session Border Controller to said fallback determination device, a query message including the 4G network cell id corresponding to the 4G network cell in which the first user device is currently located;
receiving, by said Session Border Controller, a response message in response to said query message from said fallback determination device indicating the likelihood that said first user device will be required to switch from operating in said 4G network to operating in a 3G network during the duration of a call to be setup in response to said call setup message;
making a determination, by said Session Border Controller, of whether media for said call is to be anchored in the Access Transfer Gateway (ATGW) using information contained in said response message; and
when an Internet Protocol address corresponding to the first user device changes from a first Internet Protocol address to a second Internet Protocol address during said call established in response to the call setup message transmitting the second Internet Protocol address only to the ATGW and not to the second user device.

US Pat. No. 10,341,926

HANDOVER IN HIGH SPEED SCENARIO

TELEFONAKTIEBOLAGET LM ER...

1. A method performed by a network node, for controlling handover of a wireless communication device from a source cell to a target cell, wherein the network node is maintaining a first cell at a first cell carrier frequency having a radio coverage that covers at least part of both the source cell and the target cell, wherein the source cell is maintained by a source cell node at a source cell carrier frequency, wherein the target cell is maintained by a target cell node at a target cell carrier frequency and wherein the source cell carrier frequency and the target cell carrier frequency are higher than the first cell carrier frequency, the method comprising:estimating a first performance value associated with communication between the wireless communication device and the source cell,
estimating a second performance value associated with communication between the wireless communication device and the target cell,
determining that the wireless communication device is about to move into coverage of the target cell, and
if the second performance value is greater than the first performance value, then assisting the wireless communication device to perform a handover from the source cell to the target cell by:
transmitting a handover request to the target cell,
receiving a handover request acknowledgement from the target cell, and
transmitting instructions to the wireless communication device for connecting to the target cell,
wherein any of the estimation of a first performance value and the estimation of a second performance value comprises the network node receiving at least one measurement report from any of the source cell and the target cell, said at least one measurement report comprising information indicating a signal quality of uplink RF signals from the wireless communication device received and measured by any of the source cell and the target cell.

US Pat. No. 10,341,922

RADIO BASE STATION AND RADIO TERMINAL

KYOCERA Corporation, Kyo...

1. A first base station included in a mobile communication network, comprising:a controller configured to measure a stay period for which a radio terminal has stayed on a wireless Local Area Network (LAN), wherein
the stay period is a period from when an offload process through which the radio terminal switches a waiting destination or a connection destination from the mobile communication network to the wireless LAN is performed to when a re-offload process through which the radio terminal switches the waiting destination or the connection destination from the wireless LAN to the mobile communication network is performed,
the controller is configured to determine that a ping-pong phenomenon has occurred when the measured stay period is less than a threshold,
the controller is further configured to determine whether the occurrence of the ping-pong phenomenon is attributed to a handover procedure, based on whether a re-offload indicator is received from a second base station included in the mobile communication network, the re-offload indicator indicating that the radio terminal has performed the re-offload process in which the waiting destination or the connection destination is switched from the wireless LAN to the second base station,
the controller is further configured to change a handover parameter in response to a determination that the occurrence of the ping-pong phenomenon is attributed to the handover procedure, wherein
the handover parameter is used by the radio terminal to determine whether to perform the handover procedure, and
the controller is further configured to change the handover parameter so that the handover procedure starts before the offload process.

US Pat. No. 10,341,912

ENHANCEMENT OF ACCESS POINTS TO SUPPORT HETEROGENEOUS NETWORKS

1. A system, comprising:a processor; and
a memory that stores executable instructions that, when executed by the processor, facilitate performance of operations, comprising:
receiving a data signal indicative of characteristic data representing a cell-type indicator that is indicative of a capability of a first access point device of a heterogeneous network;
based on the characteristic data, updating a neighbor relation data structure stored within a management device, of the heterogeneous network, that is accessible to a second access point device of the heterogeneous network, wherein the characteristic data comprises capacity data that represents a number of devices supported by the first access point device; and
based on the neighbor relation data structure, facilitating cell reselection for a user equipment served by the second access point device.

US Pat. No. 10,341,904

COMMUNICATION TERMINAL AND METHOD FOR SWITCHING A CALL BETWEEN RADIO ACCESS TECHNOLOGIES

Intel Corporation, Santa...

1. A user equipment device (UE) comprising:a first communication circuit configured for communication using a first radio access technology;
a second communication circuit configured for communication using a second radio access technology;
wherein the first communication circuit is configured to communicate speech data of a call using the first radio access technology;
a first buffer configured to manage jitter of the first radio access technology;
a second buffer configured to manage jitter of the second radio access technology; and
a controller configured to
control the second communication circuit to generate transport protocol packets comprising speech data of the call for uplink transmission of the speech data using the second radio access technology;
initiate a handover of the call from the first radio access technology to the second radio access technology after the second communication circuit begins generating the transport protocol packets for uplink transmission; and
to transfer unplayed transport protocol packets from the first buffer to the second buffer with a protocol packet timestamp for a next protocol packet, and to reorder the transferred unplayed protocol packets for inclusion with protocol packets received on the second communication circuit.

US Pat. No. 10,341,900

DATA TRANSMISSION METHOD, BASE STATION, AND WIRELESS COMMUNICATIONS DEVICE

Huawei Technologies Co., ...

1. A data transmission method, comprising:receiving, by a primary base station, offloading information sent by a secondary base station;
adjusting, by the primary base station according to the offloading information, offloading data that is allocated to the secondary base station;
wherein the offloading information comprises a sequence number of a last packet data unit (PDU) sent by the secondary base station to a terminal; and
wherein adjusting, by the primary base station according to the offloading information, offloading data that is allocated to the secondary base station comprises:
determining, by the primary base station according to the offloading information, that a difference between a sequence number of a first PDU that is waiting to be reordered in a reordering window and an upper boundary of the reordering window is greater than a preset value; and
adjusting, by the primary base station, the offloading data that is allocated to the secondary base station, so that the difference between the sequence number of the first PDU that is waiting to be reordered and the upper boundary of the reordering window is not greater than the preset value.

US Pat. No. 10,341,882

OPTIMIZATION OF NFC TAG FOR DIFFERENT BATTERY LEVELS

NXP USA, Inc., Austin, T...

1. A method of controlling operation of a mobile device, the method comprising:measuring a power level of a battery;
configuring the mobile device to operate in a first operating mode, including performing a first type of communication, when the measured power level of the battery is above a first predetermined threshold;
configuring the mobile device to operate in a second operating mode, in which a selected function of the first operating mode is disabled, and including performing a second type of communication when the measured power level of the battery falls below the first predetermined threshold; and
configuring the mobile device to operate in a third operating mode when the measured power level of the battery falls below a second predetermined threshold that is less than the first predetermined threshold, including performing the second type of communication with a selected communications function of the second type of communications being disabled and harvesting power for the mobile device from a magnetic field, the harvested power being sufficient to maintain a secure element in an active state.

US Pat. No. 10,341,881

SUPERVISION OF DATA IN A WIRELESS NETWORK

Vasona Networks, Inc., A...

1. A method of supervising data in a wireless network, comprising:intercepting packets en route between a base station and a packet data network, by a supervisor computer, separate from the base station;
estimating an incoming data rate to the base station for the UEs and an outgoing rate from the base station to the UEs, responsive to the intercepted packets;
noting times associated with the intercepted data packets at the supervisor computer;
identifying for each of the intercepted packets, a corresponding user equipment (UE) of the packet;
recognizing sets of the identified UEs serviced by corresponding base stations, responsively to the intercepted packets;
based on one or more of said noted times, the identified UEs, and responsive to the estimated incoming data rate and the outgoing rate, estimating, for each of the UEs, at least one parameter indicative of a fullness of at least one queue, of packets directed to the UE, in the base station;
determining for each set, a threshold dependent on current conditions to be used for all the UEs of the set;
comparing the estimated at least one parameter of each UE to the corresponding threshold of the UE;
at least partly based on a result of said comparing, determining whether or not at least one action should be performed;
if determined that any action should be performed, performing at least one action to reduce the fullness of the at least one queue; and
repeating the intercepting, estimating the incoming data rate, noting, identifying, recognizing, estimating the at least one parameter, determining, comparing and determining whether or not at least one action should be performed, periodically.

US Pat. No. 10,341,877

SYSTEM, APPARATUS AND METHOD FOR MANAGING CLIENT DEVICES WITHIN A WIRELESS NETWORK

Hewlett Packard Enterpris...

1. A network device comprising a physical processor that executes machine-readable instructions to cause the network device to:determine a plurality of client devices that include multiple frequency band capability operating on a first type of radio of the network device;
determine a plurality of client devices that include multiple frequency band capability operating on a second type of radio of the network device;
compare a ratio of the plurality of client devices on the first type of radio and the plurality of client devices operating on the second type of radio to a threshold value;
cause a subset of the plurality of client devices operating on the first type of radio to operate on the second type of radio in response to the comparison.

US Pat. No. 10,341,876

OPPORTUNISTIC SIGNAL TRANSMISSION FOR INTER-RAT CO-EXISTENCE

INTEL IP CORPORATION, Sa...

1. An evolved node B (eNB), comprising:memory; and
processing circuitry coupled to the memory, the processing circuitry to:
identify a discovery measurement timing configuration (DMTC) for opportunistic transmission of a reference signal over an unlicensed carrier, the DMTC comprising multiple subframes;
cause transmission of configuration information regarding positioning of the reference signal in one or more selected subframes of the DMTC;
determine whether the unlicensed carrier is available during the selected subframes of the DMTC; and
cause transmission of the reference signal over the unlicensed carrier during at least one subframe within the DMTC that is different from the selected subframes within the DMTC when the unlicensed carrier is not available during one of the selected subframes of the DMTC.

US Pat. No. 10,341,875

METHOD AND ARRANGEMENT FOR MULTI BAND COMMUNICATION

Telefonaktiebolaget LM Er...

1. A method for multi band communication, performed by a Radio Access (RA) node of a wireless communication network, the RA node being operable to communicate with at least one wireless device (WD) in a first frequency band, the method comprising:performing at least one measurement in a second frequency band, by use of a feedback receiver, in order to detect signals produced by other entities than the RA node; wherein the feedback receiver also is operable to measure signals transmitted by the RA node;
selecting, based on the performed at least one measurement, an operational frequency within the second frequency band for communication with the at least one WD, wherein the feedback receiver is associated with a transmitter of the RA node and is operable in the first frequency band and/or the second frequency band; and
converting, when the feedback receiver is associated with the transmitter operable in the first frequency band, a detected signal in the second frequency band to the first frequency band.

US Pat. No. 10,341,872

DYNAMIC NETWORK SLICE RESOLUTION

Verizon Patent and Licens...

1. A first device, comprising:one or more memories; and
one or more processors, communicatively coupled to the one or more memories, to:
receive an attach request that includes information associated with a user device,
the user device to provide the attach request to request access to a network;
provide, to a second device and using the information associated with the user device, a request for information associated with a group identifier that is associated with the user device;
receive, from the second device, the information associated with the group identifier that is associated with the user device based on providing the request for the information associated with the group identifier;
determine a network slice identifier that is associated with the user device based on the information associated with the group identifier,
where there is a many-to-one mapping between a plurality of group identifiers and the network slice identifier,
the plurality of group identifiers including the group identifier; and
permit the user device to access a network slice, of the network, that is associated with the network slice identifier based on determining the network slice identifier.

US Pat. No. 10,341,870

SUBSYSTEM FOR AUTHORIZATION AND ACTIVATION OF FEATURES

QUALCOMM Incorporated, S...

1. A method, operational at a device, comprising:identifying one or more selectively activated features used to enable the device to employ a network service;
identifying which of the one or more selectively activated features used to enable the device to employ the network service are not authorized to be activated at the device;
sending a request to authorize activation of the one or more selectively activated features used to enable the device to employ the network service that are not authorized to be activated at the device;
obtaining, in response to the request, authorization information and an authorization file associated with the one or more selectively activated features used to enable the device to employ the network service that are not authorized to be activated at the device; and
using the authorization information and the authorization file to activate and/or maintain activation of the one or more selectively activated features used to enable the device to employ the network service, wherein the authorization information and authorization file comprise one or more feature activation keys, authorization parameters, an authorization certificate, or any combination thereof.

US Pat. No. 10,341,866

SECURE COMMUNICATION ARCHITECTURE FOR MEDICAL DEVICES

Bigfoot Biomedical, Inc.,...

1. A computer-implemented method of establishing a secure wireless communication connection between an insulin pump device and a mobile computing device using a remote server system, the method comprising:receiving, at the mobile computing device, a device identifier for at least the insulin pump device, wherein the insulin pump device includes an insulin reservoir to store insulin to be administered to a user, a pump assembly to deliver insulin from the insulin reservoir to the user, and a controller to control operation of the pump assembly according, at least in part, to commands provided to the insulin pump by the mobile computing device;
obtaining, by the mobile computing device, device information for the insulin pump device from the remote server system using the device identifier;
establishing, by the mobile computing device, a secure wireless connection with the insulin pump device using, at least in part, the device identifier;
authenticating, by the mobile computing device, the insulin pump device based on asymmetric key verification using a public key of an asymmetric key pair, the authentication including:
sending a first challenge to the insulin pump device that includes a first value;
determining a first response based on the first value and a shared secret;
receiving the first response from the insulin pump device, wherein the insulin pump device is authenticated based on receipt of the first response;
receiving, by the mobile computing device, a second challenge from the insulin pump device that includes a second value;
determining, by the mobile computing device, a second response based on the second value and the shared secret;
sending, by the mobile computing device, the second response to the insulin pump device; and
securely communicating, by the mobile computing device and in response to authenticating the insulin pump device, information with the insulin pump device.

US Pat. No. 10,341,860

LEARNED DUAL BAND WIFI NETWORK ASSOCIATION

Apple Inc., Cupertino, C...

1. A method comprising:maintaining, by a first device, a first identifier associated with a first wireless network provided by an access point;
determining, by the first device, an item of security information used to connect to the first wireless network;
generating, by the first device, a second identifier using the first identifier, wherein the second identifier is generated based at least in part on a relationship between the first wireless network and a second wireless network provided by the access point; and
sending, by the first device, the second identifier and the item of security information to a second device, the second identifier being configured to enable the second device to connect automatically to the second wireless network using the item of security information.

US Pat. No. 10,341,853

METHODS AND SYSTEMS FOR ENABLING CONTROL OF PRIVACY FOR CROWDSOURCING

QUALCOMM Incorporated, S...

1. A method comprising:providing, to a mobile device via a server device, indications of one or more particular sources, distinct from said server device, as having one or more privacy requirements for obtaining a crowdsourcing observation by said mobile device;
receiving, at said server device, a first message from said mobile device identifying at least one source of said one or more particular sources as a candidate for obtaining said crowdsourcing observation;
determining a permitted level of crowdsourcing observation for said at least one source based, at least in part, on said one or more privacy requirements; and
transmitting a second message to said mobile device indicating said permitted level.

US Pat. No. 10,341,846

CONTROLLING IMPLEMENTATION OF SERVICES IN A MOBILE TELECOMMUNICATIONS NETWORK

Telefonaktiebolaget LM Er...

6. A method for use in a network node for controlling implementation of services in a mobile telecommunications network, the mobile telecommunications network comprising a user database for storing at least one user subscription profile, each user subscription profile associated with services implemented in at least one network domain and comprising a plurality of individual Operator Determined Barring indicators, ODBs, and respective status information, for the services associated with the user subscription profile, the method comprising:receiving, by a receiver from the user database, a user subscription profile, a master ODB indicating barring for a plurality of the services associated with the user subscription profile, and master ODB status information;
determining, by a master ODB status determiner, that the master ODB is active based on the received master ODB status information; and
initiating, by an ODB initiator, for the plurality of services, barring for all individual ODB indicators in the user subscription profile irrespective of the received status information for the individual ODB indicators.

US Pat. No. 10,341,752

REMOVABLE CARTRIDGE FOR INSERTION INTO PORTABLE COMMUNICATIONS DEVICE

MOTOROLA SOLUTIONS, Chic...

1. A portable communications device comprising:a housing;
a speaker cone disposed within the housing;
a frame having first and second surfaces, wherein the first surface is planar and the second surface is non-planar and spaced from the speaker cone;
an open gap extending between the first and second surfaces of the frame; and
a membrane coupled to the first surface of the frame, wherein a portion of the membrane is suspended over the open gap;
wherein the housing includes a battery compartment, and wherein the battery compartment defines an opening for receipt of the frame and membrane.

US Pat. No. 10,341,731

VIEW-SELECTION FEEDBACK FOR A VISUAL EXPERIENCE

Google LLC, Mountain Vie...

1. A computer-implemented method comprising:presenting a visual experience on a display of a mobile media-consumption device, the visual experience comprising:
a live-action or computer-animated film; and
a story having story views and context views, the story views presenting at least a portion of an event of an authored series of events, the context views presenting context of the visual experience, the context comprising additional detail about at least one of the story views or an element of the visual experience separate from the authored series of events;
receiving view selections during the presentation of the visual experience, the view selections non-passively made by a user during the presentation of the visual experience, the view selections received through one or more orientation sensors of the mobile media-consumption device, the view selections configured to view a part, but not all, of the visual experience, the part of the visual experience comprising at least a portion of one of the story views or a portion of one of the context views from among the story views and the context views of the story of the visual experience;
viewing, based on the received view selections, the part of the visual experience on the display;
determining, during the presentation of the part of the visual experience and based on the view selections, an alteration to a current or future story view or a current or future context view of the visual experience;
providing the alteration, during the presentation of the part of the visual experience, effective to alter the current or future story view or the current or future context view of the visual experience;
determining, based on the received view selections and the viewed part of the visual experience, one or more interest elements of the visual experience, the determined one or more interest elements of the visual experience corresponding to an interest level of the user;
aggregating the determined one or more interest elements of the visual experience into feedback;
transmitting the feedback of the visual experience;
receiving another visual experience, the other visual experience adjusted to correspond to the transmitted feedback; and
presenting the other visual experience on the display of the mobile media-consumption device.

US Pat. No. 10,341,727

INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, AND INFORMATION PROCESSING PROGRAM

Rakuten, Inc., Setaguya-...

1. An information processing apparatus comprising:at least one memory configured to store computer program code; and
at least one processor configured to access said at least one memory, read said computer program code, and operate as instructed by said computer program code, said computer program code including:
content identification information obtaining code configured to cause at least one of said at least one processor to obtain content identification information for identifying a content to be presented with respect to a user identifier C;
log retrieval code configured to cause at least one of said at least one processor to retrieve, from a storage that stores operation logs each of which is associated with content identification information for identifying a presented content and includes both a time at which an operation to control presentation of the presented content was performed during presentation of the presented content and details of the operation, operation logs corresponding to the obtained content identification information;
generating code configured to cause at least one of said at least one processor to generate control information for controlling how to present the content indicated by the obtained content identification information, in accordance with a tendency of operation changes that is identified based on the retrieved operation logs, the control information including details of control and a timing of the control, wherein
based on a frequency of appearance of each of a plurality of patterns included in the operation changes, the generating code causes at least one of said at least one processor to select at least one of the plurality of patterns and generate the control information in accordance with the selected at least one pattern, wherein a first pattern of the plurality of patterns includes a first control at a first position and Wherein the first control is associated with a first plurality of user identifiers, and wherein the first pattern of the plurality of patterns further includes a second control at a second position associated with a second plurality of user identifiers, and
providing code configured to cause at least one of said at least one processor to provide the generated control information, wherein:
the operation logs include an operation log associated with a user identifier A and an operation log associated with a user identifier B, but do not include an operation log associated with the user identifier C,
the user identifier C is different than the user identifier A, and
the user identifier C is different than the user identifier B.

US Pat. No. 10,341,717

SYSTEMS AND METHODS FOR FACILITATING ACCESS TO CONTENT ASSOCIATED WITH A MEDIA CONTENT SESSION BASED ON A LOCATION OF A USER

Verizon Patent and Licens...

1. A method comprising:determining, by a content delivery system, that a user profile of a user is logged in to a first access device during a media content session associated with the first access device in which the first access device presents media content to the user, the first access device provided at a location at a user premises;
detecting, by the content delivery system, that the user moves outside a vicinity of the first access device while the user profile is logged in to the first access device during the media content session;
identifying, by the content delivery system in response to the user moving outside the vicinity of the first access device, a second access device associated with the user and that is within a vicinity of the user;
detecting, by the content delivery system and while the user is outside the vicinity of the first access device, an occurrence of an event that occurs while the media content is presented by the first access device during the media content session, the event represented by a video highlight of a sporting event;
automatically providing, by the content delivery system in response to the identifying of the second access device and the detecting of the occurrence of the event, session management content corresponding to the media content session associated with the first access device for presentation by the second access device while the user is outside the vicinity of the first access device, the session management content comprising a notification that includes information regarding the event and an option for the user to experience the video highlight of the sporting event; and
preventing, by the content delivery system while the user profile of the user is logged in to the first access device and the user is outside the vicinity of the first access device and while the media content is presented by the first access device at the location at the user premises, the notification including the option for the user to experience the video highlight of the sporting event from being presented by way of the first access device to an additional user that is within the vicinity of the first access device and that is presented with the media content by way of the first access device while the user profile of the user is logged in to the first access device.

US Pat. No. 10,341,714

SYNCHRONIZATION OF MULTIPLE AUDIO ASSETS AND VIDEO DATA

TIME WARNER CABLE ENTERPR...

1. A method comprising the steps of:obtaining, at a personal media device in a premises, from a content source device in said premises, a secondary audio asset; and
providing, from said personal media device to said content source device, data indicative of a time delay causing said content source device to delay display of digital video data and playback of a primary soundtrack synchronizing a playback of said at least one secondary audio asset by said personal media device with said display of said digital video data and said playback of said primary soundtrack.

US Pat. No. 10,341,712

SYSTEMS AND METHODS FOR AUDIO TRACK SELECTION IN VIDEO EDITING

GoPro, Inc., San Mateo, ...

1. A system that automatically edits video clips to synchronize accompaniment by different musical tracks, the system comprising:one or more non-transitory storage media storing video content and first instructions defining a first edit of the video content, the first instructions indicating specific portions of the video content included in the first edit of the video content and an order of the specific portions of the video content within the first edit of the video content, the specific portions of the video content including a first portion and a second portion, the second portion following the first portion in the first edit of the video content, wherein:
the first edit of the video content includes one or more occurrences of video events, the individual occurrences of the video events corresponding to different moments within the first edit of the video content;
the first portion of the video content includes a first video event occurring at a first moment within the first edit of the video content;
the second portion of the video content includes a second video event occurring at a second moment within the first edit of the video content; and
the first edit of the video content is synchronized with a musical track, the musical track providing an accompaniment for the first edit of the video content, the musical track characterized by audio event markers including a first audio event marker occurring at a third moment within the musical track and a second audio event marker occurring at a fourth moment within the musical track, the fourth moment occurring later in the musical track than the third moment, the individual audio event markers corresponding to different moments within the musical track,
the first edit of the video content is synchronized with the musical track such that the first moment corresponding to the first video event is aligned to the third moment corresponding to the first audio event marker and the second moment corresponding to the second video event is aligned to the fourth moment corresponding to the second audio event marker; and
a boundary between the first portion of the video content and the second portion of the video content in the first edit of the video content is located at a given audio event of the musical track at or near a mid-point between the first video event and the second video event; and
one or more physical processors configured by machine readable instructions to:
determine a change to the musical track; and
determine second instructions defining a second edit of the video content that is synchronized with the changed musical track so that one or more moments within the second edit of the video content corresponding to one or more of the occurrences of the video events are aligned with one or more moments within the changed musical track corresponding to one or more of the audio event markers, wherein determination of the second instructions includes:
identifying the mid-point between the first video event and the second video event;
identifying an audio event of the changed musical track that is nearest to the mid-point; and
shifting the boundary between the first portion of the video content and the second portion of the video content in the second edit of the video content to be located at the audio event of the changed musical track that is nearest to the mid-point.

US Pat. No. 10,341,707

METHOD AND SYSTEM FOR USING A SECOND SCREEN DEVICE FOR INTERACTING WITH A SET TOP BOX TO ENHANCE A USER EXPERIENCE

The DIRECTV Group, Inc., ...

1. A method comprising:saving a screen image signal of a display of a second screen device;
communicating the screen image signal to a set top box;
displaying the screen image signal on the display associated with the set top box; and
wherein displaying the screen image signal comprises displaying the screen image signal through a hypertext transfer protocol engine of the set top box.

US Pat. No. 10,341,705

DIGITAL OVERLAY OFFERS ON CONNECTED MEDIA DEVICES

The Nielsen Company (US),...

1. A communication device comprising:a memory storing instructions and a plurality of offers in a virtual wallet;
private area networking (PAN) circuitry;
a display device; and
a processor coupled to the display device and configured to execute the instructions to:
pair the PAN circuitry with a television configured to enable interaction by the communication device with offers delivered in conjunction with commercials streamed to the television;
detect a first offer delivered over an offer distribution network to the communication device and in conjunction with a first broadcast commercial, the first offer including a selectable indicia, wherein an offer computing system of the offer distribution network is configured to use automatic content recognition to identify commercial metadata from the first broadcast commercial and responsively deliver the first offer to the communication device; and
deliver the first offer to the virtual wallet in response to detecting selection of the selectable indicia;
associate a tracker of the offer computing system with the first offer in the virtual wallet, the tracker managed by a third party and configured to identify redemption of the first offer at a vendor point-of-sale (POS) system and a location of the redemption of the first offer;
detect a selection of the first offer within the virtual wallet;
communicate with the vendor POS system configured to redeem the first offer in response to detecting the selection of the first offer;
update the tracker based on the communication with the vendor POS system and the location of the redemption of the first offer; and
detect a targeted offer based on the updated tracker at a time when the television receives a second broadcast commercial, the targeted offer corresponding to broadcast content of the second broadcast commercial.

US Pat. No. 10,341,699

SYSTEM FOR ADDRESSING ON-DEMAND TV PROGRAM CONTENT ON TV SERVICES PLATFORM OF A DIGITAL TV SERVICES PROVIDER

Broadband iTV, Inc., Hon...

1. A method for receiving, via a closed system, video content to be viewed on a subscriber device, having a tuner, associated with a subscriber of a video-on-demand system using a hierarchically arranged interactive electronic program guide, comprising:(a) transmitting, from the subscriber device to a television service platform, a request by the subscriber to log in to the video-on-demand system;
(b) generating, by the subscriber device in response to a first request by the subscriber after logging in to the video-on-demand system, the interactive electronic program guide to be presented to the subscriber as a templatized video-on-demand display on a display for the subscriber device to access video-on-demand programs previously stored on a video server associated with a television service provider in a digital video format as part of the video-on-demand system, wherein the subscriber device has access to a plurality of different display templates for use with the interactive electronic program guide, and wherein the interactive electronic program guide enables the subscriber using the subscriber device to navigate in a drill-down manner through titles by category information in order to locate a first of the titles whose associated video content is desired for viewing on the subscriber device using the same category information in metadata associated with the video content,
wherein the navigating through the titles in a drill-down manner comprises navigating from a first level of a hierarchical structure of the interactive electronic program guide to a second level of the hierarchical structure of the interactive electronic program guide to locate a first title;
(c) tracking, at the subscriber device, navigation data related to a navigation path taken by the subscriber in navigating through the interactive electronic program guide in the drill-down manner to select the video-on-demand programs for viewing, including the first title and the category information associated with the first title;
(d) providing, by the subscriber device to a profiling system, the tracked navigation data for the subscriber for preparing subscriber profile data, wherein the subscriber profile data is to be provided to a targeting system to generate feedback data as to subscriber preferences based at least on the subscriber profile data; and
(e) generating, by the subscriber device in response to a second request by the subscriber, an updated interactive electronic program guide to be displayed to the subscriber on the templatized video-on-demand display on the display of the subscriber device, wherein the updated interactive electronic program guide is prepared based on the feedback data from the targeting system, and wherein the generation of the updated interactive electronic program guide comprises obtaining, via an application program interface of the television service provider, the titles and the category information associated with the titles for the video-on-demand programs to populate the updated interactive electronic program guide;
wherein the templatized video-on-demand display has been generated in a plurality of layers, comprising:
(a) a first layer comprising a background screen to provide at least one of a basic color, logo, or graphical theme to display;
(b) a second layer comprising a particular display template from the plurality of different display templates layered on the background screen, wherein the particular display template comprises one or more reserved areas that are reserved for displaying content provided by a different layer of the plurality of layers; and
(c) a third layer comprising reserved area content generated using the received video content, the associated metadata, and an associated plurality of images to be displayed in the one or more reserved areas in the particular display template as at least one of text, an image, a navigation link, and a button;
wherein a first template of the plurality of different display templates is used as the particular display template for the templatized video-on-demand display for displaying the first level of the hierarchical structure of the interactive electronic program guide and wherein a second template of the plurality of different display templates is used as the particular display template for the templatized video-on-demand display for displaying the second level of the hierarchical structure of the interactive electronic program guide.

US Pat. No. 10,341,696

SYSTEM AND METHOD FOR SEAMLESS SWITCHING THROUGH BUFFERING

Visible World, LLC., Phi...

1. A method comprising:receiving a first data stream comprising at least a first segment, wherein the first segment comprises a first starting point and a first end point;
receiving a second data stream comprising at least a second segment, wherein the second segment comprises a second starting point and a second end point;
encoding the first segment for transmission at a first data rate;
encoding the second segment;
determining a switch gap size, wherein the switch gap size comprises at least a predetermined amount of time needed to switch from transmitting the first segment of the first data stream to transmitting the second segment of the second data stream;
determining a second data rate such that a difference between a first transmit time of the first segment at the first data rate and a second transmit time of the first segment at the second data rate approximates the switch gap size; and
multiplexing the encoded first segment for transmission at the second data rate and the encoded second segment such that the second starting point of the encoded second segment is synchronized with the first end point of the encoded first segment.

US Pat. No. 10,341,694

DATA PROCESSING METHOD AND LIVE BROADCASTING METHOD AND DEVICE

ALIBABA GROUP HOLDING LIM...

1. A data processing method, comprising:converting audio and video data into broadcast data in a predetermined format, and performing speech recognition on audio data in the audio and video data;
in response to text information obtained from the speech recognition comprising a preset keyword, converting the text information to a corresponding operation instruction according to a preset corresponding relationship between the keyword and the operation instruction, and sending the operation instruction to a network device; and
in response to the text information obtained from the speech recognition not comprising the preset keyword, adding text information obtained from speech recognition into the broadcast data.

US Pat. No. 10,341,688

USE OF FRAME CACHING TO IMPROVE PACKET LOSS RECOVERY

Microsoft Technology Lice...

1. A method performed with a video decoder, the method comprising:receiving a sequence of frames comprising intra-coded key frames and predicted frames, the predicted frames being encoded with reference to a respective reference frame, at least one of the frames being marked as a cached frame;
retaining the cached frame in a frame cache at the decoder;
sending a signal indicating the cached frame;
detecting loss for a frame sent to the decoder, the lost frame being encoded with reference to a first reference frame different than the cached frame;
responsive to the detecting loss, receiving a new frame, the new frame being encoded with reference to the cached frame;
decoding the new frame with reference to the cached frame; and
producing a reconstructed frame sequence based on the decoded new frame.

US Pat. No. 10,341,687

ASSIGNING VIDEOS TO SINGLE-STREAM AND MULTI-STREAM DECODERS

Google LLC, Mountain Vie...

1. A method comprising:assigning, by a processing device, a first plurality of videos to a plurality of hardware decoders having a first configuration, wherein the hardware decoders in the first configuration are to decode the first plurality of videos for concurrent presentation on a display of a user device, wherein each of the hardware decoders in the first configuration is configured in a mode selected from a plurality of modes comprising a single-stream mode and a multi-stream mode;
receiving an indication that a second plurality of videos are to be presented on the display of the user device;
determining a second configuration of the hardware decoders based on an estimated delay penalty for the second configuration, wherein the estimated delay penalty is indicative of a time delay of decoding the second plurality of videos at the hardware decoders configured in the second configuration; and
assigning, by the processing device, the second plurality of videos to the hardware decoders for decoding according to the second configuration.

US Pat. No. 10,341,682

METHODS AND DEVICES FOR PANORAMIC VIDEO CODING AND DECODING BASED ON MULTI-MODE BOUNDARY FILL

Peking University Shenzhe...

1. A method for encoding panoramic videos based on multi-mode boundary fill, comprising:dividing a current image into a plurality of image blocks;
obtaining a predicted image block of a current image block using inter-frame prediction, wherein the inter-frame prediction comprises a step of boundary filling, comprising:
when a reference sample of a pixel in the current image block is outside a boundary of a corresponding reference image, adaptively selecting a boundary fill method comprising a cyclic fill method for filling a horizontal image boundary or a vertical image boundary, according to coordinates of the reference sample to obtain a sample value of the reference sample, wherein the cyclic fill method includes:
identifying a reference sample having a first coordinate within the reference image and a second coordinate outside of the reference image, wherein the reference image has a first dimension along direction of the first coordinate and a second dimension along direction of the second coordinate; and
assigning a sample value of a sample point within the reference image to the reference sample, wherein the sample point has a first coordinate the same as the reference sample and a second coordinate determined by a modulo operation of the second coordinate of the reference sample based on the second dimension of the reference image;
subtracting the current image block from the predicted image block to obtain a residual block; and
transforming, quantizing, and entropy encoding the residual block to obtain an encoded stream, wherein the boundary fill method selected in the step of boundary filling is written in a sequence header or an image header of the encoded stream.

US Pat. No. 10,341,674

METHOD AND DEVICE FOR DISTRIBUTING LOAD ACCORDING TO CHARACTERISTIC OF FRAME

SAMSUNG ELECTRONICS CO., ...

1. A method for distributing a load, the method comprising:identifying characteristics of each of frames included in a received bit stream; and
distributing loads of a plurality of cores based on the characteristics of each of the frames whenever the frames are decoded,
wherein the identifying comprises identifying a reference relationship between the frames included in the bit stream, and
wherein the reference relationship is distance information indicating a relative distance between a first frame to be encoded and a second frame, which is a reference frame, in a sequential picture order of the frames included in the received bit stream.

US Pat. No. 10,341,672

METHOD AND SYSTEM FOR MEDIA SYNCHRONIZATION

KOREA ADVANCED INSTITUTE ...

1. A method for media synchronization, comprising: collecting stream source information; generating network delay information between stream sources by performing a delay test between the stream sources; setting synchronization information of a stream source corresponding to a specific channel based on the collected stream source information and the network delay information; measuring network delay with at least one user terminal to receive the stream source; updating the synchronization information based on the measured network delay; and performing time synchronization with the at least one user terminal based on a time clock of the at least one user terminal comprisingrequesting the time clock of a corresponding terminal to each of a plurality of user terminals when the plurality of user terminals requests to provide the stream source; receiving the time clock of a corresponding terminal from each of the plurality of user terminals in response to the requesting of the time clock; and performing time synchronization between the plurality of user terminals based on the received time clock comprising
generating a common time stamp based on the time clock of the corresponding terminal and identifier
information of the corresponding terminal; and providing a stream inserted with the generated common time stamp to each of the plurality of user terminals.

US Pat. No. 10,341,671

METHOD AND SYSTEM FOR IMAGE COMPRESSION

XEROX Corporation, Norwa...

1. An image compression method comprising:compressing an input image with a first compression method to generate a first compressed image;
compressing the same input image with a second compression method to generate a second compressed image;
comparing the generated first compressed image and the generated second compressed image and, based on the comparison, generating:
a first residual layer comprising first pixels corresponding to foreground pixels that are present in only the second of the first and second compressed images, and
a second residual layer comprising second pixels corresponding to foreground pixels that are present in only the first of the first and second compressed images;
identifying connected components, where present, in the at least one of the first and second residual layers, each connected component comprising a group of first or second pixels in the respective first or second residual layer that, when mapped to the second compressed image is connected, in at least one of first and second directions, to foreground pixels in the second compressed image;
generating an output compressed image comprising at least one of:
for a connected component identified in the first residual layer, removing at least one corresponding foreground pixel from the second compressed image, and
for a connected component identified in the second residual layer, adding at least one corresponding foreground pixel to the second compressed image.

US Pat. No. 10,341,669

TEMPORALLY ENCODING A STATIC SPATIAL IMAGE

Intel Corporation, Santa...

1. A system for temporally encoding static spatial images, the system comprising:electronic circuitry; and
a memory including instructions that, when executed by the electronic circuitry, cause the electronic circuitry to:
obtain a static spatial image, the static spatial image defining pixel values over an area;
select a scan path, the scan path defining:
a path across the area of the static spatial image; and
a duration path, the duration path being a non-linear function that defines progression of the scan path in time;
scan a window in accordance with the scan path on the static spatial image to produce changes in a portion of the window over time; and
record the changes in the portion of the window with respective times of the changes.

US Pat. No. 10,341,662

METHODS AND SYSTEMS FOR ENTROPY CODER INITIALIZATION

Velos Media, LLC, Dallas...

1. A method for decoding a video bitstream comprising: decoding, in a slice header associated with a picture, a first syntax element with an integer value indicating a number of a plurality of entropy slices defining a first slice, wherein each of the entropy slices contains a plurality of largest coding units (LCUs); decoding a second syntax element in the slice header indicating an offset with an index i, wherein the index i has as range from 0 to the integer value of the first syntax element minus 1 and the offset indicates, in a unit of bytes, a distance between (i) one of the plurality of the entropy slices in the first slice in the video bitstream and (ii) an entropy slice preceding the one of the plurality of the entropy slices in the video bitstream;decoding a third syntax element in the slice header indicating a slice type of the first slice;
in circumstances where the third syntax element indicates the slice type of the first slice is a B slice, decoding a flag in the slice header indicating an initialization method of a Context-Adaptive Binary Arithmetic Coding (CABAC) context;
in circumstances where the decoded flag indicates a first value, initializing the CABAC context using a first initialization method at the first LCU of each of the plurality of entropy slices in the B slice;
in circumstances where the decoded flag indicates a second value, initializing the CABAC context using a second initialization method at the first LCU of each of the plurality of entropy slices in the B slice; and
initializing the CABAC context of a P slice using at least one of the first initialization method and the second initialization method.

US Pat. No. 10,341,653

METHOD AND SYSTEM FOR REDUCING SLICE HEADER PARSING OVERHEAD IN VIDEO CODING

Texas Instruments Incorpo...

1. A method for decoding a slice of picture from a bit stream when weighted prediction is enabled for the slice, the method comprising:decoding a first sequence of luminance weight flags corresponding to a first plurality of reference pictures from the bit stream;
decoding a first sequence of chrominance weight flags corresponding to the first plurality of reference pictures from the bit stream, wherein the encoded first sequence of chrominance weight flags follows the encoded first sequence of luminance weight flags in the bit stream;
decoding luminance weighting factors for each luminance weight flag of the first sequence of luminance weight flags that is set to indicate weighted prediction of a luminance component of a corresponding reference picture is enabled, wherein the encoded luminance weighting factors follow the encoded first sequence of chrominance weight flags in the bit stream; and
decoding chrominance weighting factors for each chrominance weight flag of the first sequence of chrominance weight flags that is set to indicate weighted prediction of chrominance components of a corresponding reference picture is enabled, wherein the encoded chrominance weighting factors follow the encoded luminance weighting factors in the bit stream.

US Pat. No. 10,341,644

OMNISTEREO CAPTURE AND RENDER OF PANORAMIC VIRTUAL REALITY CONTENT

GOOGLE LLC, Mountain Vie...

1. A system comprising:at least one processor;
memory storing instructions that, when executed by the at least one processor, cause the system to perform operations including:
receiving a set of images based on captured video streams collected from at least one stereo pair of cameras;
calculating optical flow between images from the set of images to generate a plurality of image frames that are not part of the set of images, the calculating of the optical flow including analyzing image intensity fields for selected columns of pixels associated with the set of images;
interleaving the plurality of image frames into the set of images at the respective selected columns of pixels and stitching together a portion of the plurality of image frames and the set of images based at least in part on the optical flow; and
generating, using the portion of the plurality of image frames and the set of images, an omnistereo panorama.

US Pat. No. 10,341,643

PROCESS AND SYSTEM FOR ENCODING AND PLAYBACK OF STEREOSCOPIC VIDEO SEQUENCES

3DN, LLC, Ottawa (CA)

1. A method for displaying images, comprising:in a conventional two-dimensional (2D) viewing mode:
driving a 2D image of a plurality of 2D images to a head mountable display; and
in a stereoscopic three-dimensional (3D) viewing mode:
driving to the head mountable display a left image of a plurality of left images for left eye viewing, wherein at least a portion of the plurality of left images are generated using time interpolation to increase a frame rate of the display, and a right image of a plurality of right images for right eye viewing, the left image and the right image being time-synchronized with parallax for perception of depth in the stereoscopic 3D viewing mode, wherein the driving comprises simultaneous dual presentation of the left image and the right image.