US Pat. No. 11,110,006

NON-INVASIVE AND MINIMALLY INVASIVE LASER SURGERY FOR THE REDUCTION OF INTRAOCULAR PRESSURE IN THE EYE

ViaLase, Inc., Aliso Vie...


1. A method of reducing intraocular pressure in an eye, the eye having a Schlemm's canal with fluid therein, and one or more collector channels branching from the Schlemm's canal, the method comprising:placing a focus of a laser beam into the Schlemm's canal; and
delivering the laser beam into the Schlemm's canal to initiate a photo-disruptive interaction with the fluid inside the Schlemm's canal to create a pneumatic effect that expands the Schlemm's canal by operating the laser beam with a pulse duration between 10 femtoseconds and 1 nanosecond and a pulse wavelength between 330 nanometers and 2000 nanometers; and
maintaining the focus of the laser beam inside the Schlemm's canal to avoid photo-disruptive interactions with tissue surrounding the Schlemm's canal.

US Pat. No. 10,821,023

INTEGRATED SURGICAL SYSTEM AND METHOD FOR TREATMENT IN THE IRIDO-CORNEAL ANGLE OF THE EYE

ViaLase, Inc., Aliso Vie...

1. A method of reducing intraocular pressure in an eye having a cornea, an anterior chamber, and an irido-corneal angle comprising an aqueous humor outflow pathway formed of a trabecular meshwork, a Schlemm's canal, and one or more collector channels branching from the Schlemm's canal, the method comprising:delivering each of an optical coherence tomography (OCT) beam and a laser beam through the cornea, and the anterior chamber into the irido-corneal angle, the OCT beam and laser beam being delivered from a second optical subsystem optically coupled to a first optical subsystem including a window configured to be coupled to the cornea, and an exit lens configured to be coupled to the window, wherein each of the window and exit lens comprises a concave surface and a convex surface; and
modifying a volume of ocular tissue within the outflow pathway to reduce a pathway resistance present in one or more of the trabecular meshwork, the Schlemm's canal, and the one or more collector channels by applying the laser beam to ocular tissue defining the volume to thereby cause photo-disruptive interaction with the ocular tissue to reduce the pathway resistance or create a new outflow pathway.

US Pat. No. 10,821,024

SYSTEM AND METHOD FOR ANGLED OPTICAL ACCESS TO THE IRIDO-CORNEAL ANGLE OF THE EYE

ViaLase, Inc., Aliso Vie...

1. An optical system for directing a light beam to an irido-corneal angle of an eye, the eye having a direction of view and a cornea with a refractive index nc, the optical system comprising:a first optical subsystem having optical aberrations, and comprising:
a window formed of a solid optical material with a refractive index nw , the window having a concave surface and a convex surface opposite the concave surface, and
an exit lens formed of a solid optical material having a refractive index nx, the exit lens having a concave surface and a convex surface opposite the concave surface, wherein the concave surface of the exit lens is configured to couple to the convex surface of the window to define a first optical axis extending through the window and the exit lens; and
a second optical subsystem configured to output a light beam, wherein:
the first optical subsystem is optimized for angled optical access that at least partially compensates for the optical aberrations of the first optical subsystem, the angled optical access being along a second optical axis at an angle a that is offset from the first optical axis,
the light beam is directed to be incident at the convex surface of the exit lens along the second optical axis,
the concave surface of the window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with the direction of view, and
the respective refractive indices nw, and nx are configured to direct the light beam incident at the convex surface of the exit lens through the cornea of the eye toward the irido-corneal angle.