US Pat. No. 9,044,347

HYBRID BIOELECTRICAL INTERFACE DEVICE

The Regents of The Univer...

1. A hybrid bioelectrical interface device for interfacing living neural tissue with electronic devices comprising:
an abiotic component operable to transmit charge via electrons or ions;
a biological component interfacing with the neural tissue, said biological component comprising an acellularized tissue construct;
a conjugated polymer component interfacing said abiotic component and said biological component, said conjugated polymer component
promoting electronic to ionic charge transfer between said abiotic and biological components; and

a housing encapsulating at least a portion of said biological component, said conjugated polymer component and said abiotic
component.

US Pat. No. 9,566,372

SUSTAINED NITRIC OXIDE RELEASE COATING USING DIAZENIUMDIOLATE-DOPED POLYMER MATRIX WITH ESTER CAPPED POLY(LACTIC-CO-GLYCOLIC ACID) ADDITIVE

The Regents of the Univer...

1. A polymeric composition, comprising:
a polymer matrix having at least one of a lipophilic discrete nitric oxide adduct or a polymeric nitric oxide adduct associated
therewith, by: covalent attachment to the polymeric matrix; dispersion within the polymeric matrix; or both, with the at least
one of the discrete nitric oxide adduct or the polymeric nitric oxide adduct capable of releasing nitrous oxide (NO); and

an ester capped poly(lactide-co-glycolide) (PLGA) additive to at least one of increase, prolong, and control NO release rates
from the at least one of the lipophilic discrete nitric oxide adduct or the polymeric nitric oxide adduct, the ester capped
PLGA additive having a 65:35 ratio of lactic acid monomer to glycolic acid monomer.

US Pat. No. 9,065,093

CONTROLLED POROSITY IN ELECTRODES

Massachusetts Institute o...

1. An electrode, comprising:
a matrix material comprising high-tortuosity pores having tortuosities of at least 2; and
a plurality of low-tortuosity pores having tortuosities of less than 1.5 extending through the matrix material and from a
first external geometric surface of the electrode to a second external geometric surface of the electrode, wherein:

the electrode has a total porosity of from 20% to 60%, and
the percentage of the total porosity that is occupied by the low-tortuosity pores is from 20% to 80%.

US Pat. No. 9,448,875

ERROR RECOVERY WITHIN INTEGRATED CIRCUIT

ARM Limited, Cambridge (...

1. An integrated circuit for performing data processing, said integrated circuit comprising:
an error detector configured to detect errors in operation of said integrated circuit;
error-repair circuitry configured to repair errors in operation of said integrated circuit; and
a power supply configured to apply a power supply voltage to at least one portion of said integrated circuit, wherein:
said power supply is configured to vary an error rate within said at least one portion by varying said power supply voltage
to said at least one portion;

said power supply voltage to said at least one portion is provided via one or more power gates configured to vary said power
supply voltage to said at least one portion; and

said power supply is controlled to produce a finite non-zero error rate within said at least one portion.

US Pat. No. 9,164,842

ERROR RECOVERY WITHIN INTEGRATED CIRCUIT

ARM Limited, Cambridge (...

1. An integrated circuit for performing data processing, said integrated circuit comprising:
a latch configured to receive and to store a signal value;
an error detector configured to detect errors in operation of said integrated circuit by detecting a late arriving transition
in said signal value received by said latch;

error-repair circuitry configured to repair errors in operation of said integrated circuit
a plurality of processing stages, a processing stage output signal from at least one processing stage being supplied as a
processing stage input signal to a following processing stage, wherein said at least one processing stage comprises:

processing logic configured to perform a processing operation upon at least one processing stage input value to generate a
processing logic output signal;

a non-delayed latch configured to capture a non-delayed value of said processing logic output signal at a non-delayed capture
time, said non-delayed value being supplied to said following processing stage as said processing stage output signal following
said non-delayed capture time; and

a delayed latch configured to capture a delayed value of said processing logic output signal at a delayed capture time later
than said non-delayed capture time;

wherein said error detector comprises a comparator configured to compare said non-delayed value and said delayed value to
detect a change in said processing logic output signal following said non-delayed capture time indicative of said processing
logic not having finished said processing operation at said non-delayed capture time; and said error-repair logic is configured,
when said comparator detects said change, to perform an error-repair operation suppressing use of said non-delayed value by
said following processing stage.

US Pat. No. 9,429,636

ADAPTIVE KEYHOLE COMPRESSION FOR DYNAMIC CONTRAST-ENHANCED MRI

Koninklijke Philips N.V.,...

1. A magnetic resonance imaging system, comprising:
a sequence control unit configured to control a magnetic resonance scanner to perform dynamic imaging by acquiring compressed
magnetic resonance data from an imaged region of a subject including fully sampling a central portion of k-space and partially
sampling a peripheral portion of k-space;

a sampling unit which determines a rate of change in a concentration of a contrast agent present in the image region of the
subject during the dynamic imaging based on magnetic resonance signals received by a radio frequency receiver; and

a control unit which adjusts a degree of compression of the acquired magnetic resonance data during the dynamic imaging based
on the determination made by the sampling unit;

wherein the control unit adjusts gradient fields to decrease the central portion of k-space and increase the peripheral portion
of k-space in response to an increase in the rate of change in the concentration of the contrast agent and adjusts the gradient
fields to increase the central portion of k-space and decrease the peripheral portion of k-space in response to a decrease
in the rate of change in the concentration of the contrast agent.

US Pat. No. 9,233,086

INHIBITION OF WDR5 INTERACTION WITH ITS BINDING PARTNERS

THE REGENTS OF THE UNIVER...

1. A composition comprising (a) a peptidomimetic compound having a structure

wherein R1 is selected from the group consisting of CH3—, —CH(CH3)2, —CH2CH3, —CH2CH2CH3, —(CH2)3CH3, cyclopropyl, cyclobutyl, cyclopentyl, phenyl, benzyl, or —NH(CH3);

R2, and R2?, independently, are selected from the group consisting of —H; C1-9 substituted or unsubstituted straight chain or branched alkyl, C3-7 cycloalkyl; —(CH2)n—U, wherein U is substituted or unsubstituted phenyl or heteroaryl and n=0-6; —C(A)(B)(D) wherein A is selected from the group
consisting of —H, —OH, —OCH3, —NH2, —NHCH3, —N(CH3)2, —SH, —SCH3, and B and D, independently, are selected from the group consisting of H, substituted or unsubstituted C1-6 straight chain or branched alkyl, C3-7 cycloalkyl, and —(CH2)n—U, wherein U is substituted or unsubstituted phenyl or heteroaryl and n=0-6; or

R2 and R2? together with the carbon atom to which they are attached can form a C3-7 carbocyclic ring;

R5 and R5?, independently, are selected from the group consisting of —H; —CH2CH2CO2H; C1-9 substituted or unsubstituted straight chain or branched alkyl, C3-7 cycloalkyl; —(CH2)n—U, wherein U is substituted or unsubstituted phenyl and n=0-6; —C(A)(B)(D) wherein A is selected from the group consisting
of —H, —OH, —OCH3, —NH2, —NHCH3, —N(CH3)2, —SH, —SCH3, and B and D, independently, are selected from the group consisting of H, substituted or unsubstituted C1-6 straight chain or branched alkyl, and C3-7 cycloalkyl, —(CH2)n—U, wherein U is substituted or unsubstituted phenyl and n=0-6; or

R5 and R5? together with the carbon atom to which they are attached can form a C3-7 carbocyclic ring or R5 and R5? are null;

R3 is H or substituted or unsubstituted C1-6 straight chain or branched alkyl, or C3-7 cycloalkyl;

R4 is —H, C1-6alkyl, —(CH2)n-E, arylE,

wherein n=2-6 and E is selected from the group consisting of —NH2, —NHCH3, —N(CH3)2, —N+(CH3)3, —FL-C(?NJ)NKK?, —FL-C(?O)NKK?, and —FL-C(?S)NKK?, wherein F is C1-6alkyl, aryl, N, or CH, and L, J, K, K?, independently, are H or —CH3;
R4? is —H, a C1-6 straight chain or branched alkyl, or C3-7cycloalkyl, each unsubstituted or substituted with one or more halogen or OH;

R6 is selected from the group consisting of C3-7 cycloalkyl; —C(?O)N(M)Q, wherein M is H and Q is selected from the group consisting of —H, C1-12 straight chain or branched alkyl, C3-7 cycloalkyl, phenyl, or benzyl, wherein each optionally is substituted with one or more of —OH, —OCH3, —NH2, —NHCH3, —N(CH3)2 or halogen, and, CHP?P?, wherein P? and P?, independently, are selected from the group consisting of unsubstituted or substituted
phenyl or benzyl, or M and Q together with the nitrogen atom to which they are attached can form a 3 to 8 membered ring;

wherein a phenyl group is optionally substituted with one or more halo, alkyl, alkenyl, —OCF3, —NO2, —CN, —NC, —OH, alkoxy, amino, alkylamino, —CO2H, —CO2alkyl, aryl, heteroaryl, and a C1-9 straight chain or branched chain alkyl group is optionally substituted with halo, trifluoromethyl, trifluoromethoxy, hydroxy,
alkoxy, nitro, cyano, alkylamino, or amino;

or a pharmaceutically acceptable salt thereof, (b) an optional second therapeutic agent useful in a treatment of a cancer;
and (c) an excipient and/or pharmaceutically acceptable carrier.

US Pat. No. 9,394,888

SYSTEM WITH DAMPER-CONTROLLED SWITCH FOR SHAPE MEMORY ALLOY ACTUATOR MOTION CONTROL

GM Global Technology Oper...

1. A system for controlling motion of a shape memory alloy actuator, the system comprising:
a damper operatively connectable to the shape memory alloy actuator and having a movable portion configured to move with the
shape memory alloy actuator when the shape memory alloy actuator contracts during electrical activation;

an electronic switch operatively connectable to the shape memory alloy actuator and to the damper; wherein the electronic
switch has an open position in which electrical power flow to the shape memory alloy actuator through the electronic switch
is prevented, and a closed position in which electrical power flow to the shape memory alloy actuator through the electronic
switch is permitted;

a biasing element applying a biasing force to the damper that urges the electronic switch to the closed position; and
wherein the damper is configured to overcome the biasing force of the biasing element to move the switch to the open position
only when a velocity of the movable portion equals or exceeds a predetermined threshold velocity, and to return to the closed
position due to the biasing force of the biasing element when the velocity of the movable portion falls below the predetermined
threshold velocity.

US Pat. No. 9,065,010

NON-PLANAR INORGANIC OPTOELECTRONIC DEVICE FABRICATION

Universal Display Corpora...

1. A method of fabricating an optoelectronic device, the method comprising:
creating an optoelectronic structure on a first substrate, wherein the optoelectronic structure includes a release layer and
a plurality of inorganic semiconductor layers supported by the release layer, the plurality of inorganic semiconductor layers
being arranged in a stack and configured to be active in operation of the optoelectronic device;

attaching permanently the plurality of inorganic semiconductor layers to a second substrate via a cold weld bond with an electrode
contact for the optoelectronic structure, the electrode contact being disposed on the first substrate before attaching the
plurality of inorganic semiconductor layers to the second substrate, the second substrate being flexible;

transferring the plurality of inorganic semiconductor layers of the optoelectronic structure from the first substrate to the
second substrate by releasing, via the release layer, the plurality of inorganic semiconductor layers from the first substrate
after the attaching step; and

deforming the second substrate and the plurality of inorganic semiconductor layers to a non-planar configuration.
US Pat. No. 9,107,883

COMPOUNDS AND METHODS FOR TREATING ABERRANT ADRENOCARTICAL CELL DISORDERS

Atterocor, Inc., Ann Arb...

1. A method for treating adrenocortical carcinoma in a target patient in need thereof comprising administering a therapeutically
effective amount of N-(2,6-bis(1-methylethyl)phenyl)-N?-((1-(4-(dimethylamino)phenyl)cyclopentyl)-methyl)urea hydrochloride
to the patient.

US Pat. No. 9,180,029

POROUS BIDIRECTIONAL BELLOWED TRACHEAL RECONSTRUCTION DEVICE

The Regents Of The Univer...

1. An implantable splinting device for supporting a defect in a passageway of a human or other animal subject comprising:
one or more bellow support structures together defining a structural component that substantially conforms to at least a portion
of the passageway and a plurality of apertures defined in at least a portion of the one or more bellow support structures,
wherein the one or more bellow support structures comprise a biocompatible polymeric material, so that the structural component
is capable of restricting displacement to less than 10% under a direct compression load of about 50 Newtons (N), while permitting
outward radial displacement of at least 100% of an initial diameter of the structural component under non-stress conditions
under a radial pressure of about 50 Newtons (N).

US Pat. No. 9,113,535

FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS

The University of Souther...

1. A compound comprising a non-activated porphyrin fused with one or more non-activated polycyclic aromatic rings, said compound
having a formula selected from the group consisting of:

M is any element selected from the group consisting of Mg, Ca, Sr, Ba, Sc, Y, La, Ce, Ti, Nb, Ta, Cr, Mo, W, Mn, Tc, Re, Fe,
Ru, Os, Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag, Au, Zn, Cd, Hg, Al, Ga, In, Ti, Si, Ge, Sn, Pb, P, As, Sb, Bi, Pr, Nd, Sm, Eu, Gd,
Tb, Dy, Ho, Er, Tm, Yb, Lu, Th, and U;

wherein R1, R3-R5, R7-R8 and R51-R82 are independently selected from the group consisting of hydrogen, alkyl, fluoroalkyl, hydroxyl, halo, mercapto group, amino,
cyano, alkenyl, alkynyl, and aryl,

wherein R2 and R6 are independently selected from the group consisting of hydrogen, alkyl, fluoroalkyl, hydroxyl, alkoxy, halo, mercapto group,
amino, cyano, alkenyl, alkynyl, 3,5-di-tert-butylphenyl, and aryl, and

wherein adjacent substituents R51-R82 optionally form fused rings, wherein the fused rings are aromatic, unsaturated, or combinations of both aromatic and unsaturated
rings, including four, five, six, seven, eight, or nine-membered rings, wherein the fused rings can include one or more heteroatoms
independently selected from the group consisting of O, S, Se, Te, N, P, As, Si, Ge, and B.

US Pat. No. 9,267,133

PHAGE MICROARRAY PROFILING OF THE HUMORAL RESPONSE TO DISEASE

THE REGENTS OF THE UNIVER...

1. A panel for detecting autoantibodies indicative of cancer from a subject, the panel comprising two or more tumor antigens,
wherein at least one of said tumor antigens comprises an amino acid sequence comprising SEQ ID NO. 407 or SEQ ID NO. 402 wherein
each of said tumor antigens is attached to a surface.
US Pat. No. 9,107,940

COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES

The Regents of the Univer...

1. A method of treating or reducing diaphragm skeletal muscle injury or diaphragm skeletal muscle deficiency in a subject
comprising administering to a subject in need thereof a composition comprising a therapeutically effective amount of a poloxamer.

US Pat. No. 9,390,496

COLLAGEN D-SPACINGS IN FIBRIL BUNDLES

The Regents Of The Univer...

1. A method of determining a collagen fibril morphology value in a tissue sample in a subject that can be compared to values
from a control subject to indicate the possible presence or not of disease or other condition, the method comprising:
a) imaging the tissue sample to make a sample image;
b) measuring data from the sample image representing D-periodic gap/overlap spacing of a plurality of collagen fibrils in
each of a plurality of fibril bundles;

c) computing a 2-D Fourier transform of the data to obtain D-spacing values describing the structure of collagen; and
d) analyzing the D-spacing values with a statistical method that takes into account bundle-to-bundle variation in collagen
D-spacing to obtain the collagen fibril morphology value.

US Pat. No. 9,054,335

CONCAVE-HEMISPHERE-PATTERNED ORGANIC TOP-LIGHT EMITTING DEVICE

The Regents of the Univer...

1. A first device comprising an organic light emitting device, the organic light emitting device comprising:
a first electrode;
a second electrode;
an organic emissive layer disposed between the first and second electrodes;
wherein the second electrode is more transparent than the first electrode; and
a first portion of the organic emissive layer has a shape that forms an indentation in the direction of the first electrode;
and

a second portion of the organic emissive layer has a shape that forms a protrusion in the direction of the second electrode.
US Pat. No. 9,303,055

LINKERS AND CO-COUPLING AGENTS FOR OPTIMIZATION OF OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION ON SOLID SUPPORTS

THE REGENTS OF THE UNIVER...

1. A method for synthesizing oligonucleotides at predetermined sites on a substrate comprising:
a) providing:
i) a substrate;
ii) a plurality of non-cleavable linkers;
iii) a plurality of anchor moieties, wherein said anchor moieties comprise the structure —C(X)—C(Y), wherein X comprises —OPO2O—, Y is a nucleophile and wherein said structure is part of a ring moiety;

iv) nucleotide monomers; and
v) co-coupling agents;
b) derivatizing said substrate with said plurality of non-cleavable linkers;
c) attaching said anchor moieties to said non-cleavable linkers to form a plurality of substrate-linker group-anchor group
moieties; and

d) synthesizing, utilizing said monomers and co-coupling agents, an oligonucleotide on each of said plurality of substrate-linker
group-anchor group moieties.

US Pat. No. 9,284,609

RECURRENT GENE FUSIONS IN PROSTATE CANCER

THE REGENTS OF THE UNIVER...

1. A composition comprising an oligonucleotide probe covalently labeled with a detectable label and comprising a sequence
that hybridizes to a junction of a chimeric nucleic acid molecule in which a 5? portion of the chimeric nucleic acid molecule
is from a TMPRSS2 gene and a 3? portion of the chimeric nucleic acid molecule is from an ETS family member gene, wherein the
ETS family member gene is selected from the group consisting of ERG, ETV1 (ER81), FLI1, ETS1, ETS2, ELK1, ETV6 (TEL1), ETV7
(TEL2), GABPa, ELF1, ETV4 (E1AF; PEA3), ETV5 (ERM), ERF, PEA3/E1AF, PU.1, ESE1/ESX, SAP1 (ELK4), ETV3(METS), EWS/FLI1, ESE1,
ESE2 (ELF5), ESE3, PDEF, NET (ELK3; SAP2), NERF (ELF2), and FEV.

US Pat. No. 9,186,631

SUPERHYDROPHILIC AND OLEOPHOBIC POROUS MATERIALS AND METHODS FOR MAKING AND USING THE SAME

The Regents Of The Univer...

1. A porous material comprising a porous substrate having a surface that is both superhydrophilic, having a first apparent
advancing dynamic contact angle of less than or equal to about 5° for water and oleophobic having a second apparent advancing
dynamic contact angle of greater than or equal to about 90° for a preselected oil, wherein the surface comprises a cross-linked
material formed from a polymer comprising poly(ethylene glycol) diacrylate (PEDGA), a low surface energy material comprising
1H, 1H, 2H, 2H-heptadecafluorodecyl polyhedral oligomeric silsequioxane (F-POSS), and a cross-linker comprising 2-hydroxy-2-methyl
propiophenone.

US Pat. No. 9,079,913

SPIRO-OXINDOLE MDM2 ANTAGONISTS

THE REGENTS OF THE UNIVER...

1. A compound that is:

US Pat. No. 9,062,368

METHOD OF MONITORING PHOTOACTIVE ORGANIC MOLECULES IN-SITU DURING GAS-PHASE DEPOSITION OF THE PHOTOACTIVE ORGANIC MOLECULES

The Regents of the Univer...

1. A method of monitoring organic materials in-situ during a deposition process for depositing a film of one or more photoactive
organic materials from one or more gas-phase photoactive organic materials onto a substrate in a processing chamber, the method
comprising:
(a) irradiating at least one of the one or more gas-phase photoactive organic materials at a monitored region inside the processing
chamber with a radiation beam in-situ during the deposition process, thereby generating a photoluminescence emission having
an intensity from the at least one of the one or more gas-phase photoactive organic materials being irradiated;

(b) measuring the intensity PPL of the photoluminescence emission from the at least one of the one or more gas-phase photoactive organic materials being irradiated;

(c) for each gas-phase photoactive organic material being irradiated, determining from the intensity of the photoluminescence
emission, at least one processing parameter associated with depositing the gas-phase photoactive organic material,

wherein the at least one processing parameter is a concentration level cp of the gas-phase photoactive organic material; and

(d) calibrating the deposition process before step (a) by calculating a concentration conversion factor kc for each gas-phase photoactive organic material being irradiated, wherein the calibrating step comprises:

(e) depositing a sacrificial calibration film of the gas-phase photoactive organic material on a sacrificial calibration substrate
for a fixed time duration using known process conditions, wherein the gas-phase photoactive organic material has a calibration
concentration level cp,exp in the processing chamber;

(f) irradiating the gas-phase photoactive organic material in the monitored region during step (e), resulting in a photoluminescence
emission and measuring the intensity PPL,exp of the photoluminescence emission;

(g) measuring the sacrificial calibration film's thickness;
(h) calculating deposition rate rdep,exp of the calibration film by dividing the calibration film's thickness by the fixed time duration;

(i) where the deposition process is a VTE process and the processing chamber is a VTE deposition chamber provided with an
evaporation source crucible for producing the gas-phase or organic photoactive material, calculating the calibration concentration
level cp,exp of the gas-phase photoactive organic material by using equation (21) below,


where r0,p is the distance from the evaporation source crucible to the monitored region,

rp is the distance from the evaporation source crucible to the monitored region,

rs is the distance from the evaporation source crucible to the center of the substrate,

r0,s is the distance from the evaporation source crucible to the surface of the substrate along the diffusion axis,

?org is molar density of the deposited organic material, or

where the deposition process is an OVPD process and the processing chamber is an OVPD deposition chamber, calculating the
calibration concentration level cp,exp by using equation (23) below,


where Jdep is the organic species flux onto the substrate;

?BL is the boundary layer thickness, the boundary layer being formed by the carrier gas on top of the substrate through which
the organic molecules must diffuse in order to condense on the substrate and form a film of a certain thickness;

Dorg is diffusivity of organic molecules in the carrier gas;

?org is the molar density of the deposited organic material; and

rdep is the film deposition rate onto the substrate; and

(j) calculating the concentration level conversion factor kc by using the following equation (15):


where PPL,baseline is the average baseline intensity in the processing chamber detected by the photodetector before any photoactive organic materials
for the deposition process is introduced into the processing chamber.

US Pat. No. 9,601,103

METHODS AND DEVICES FOR GENERATING HIGH-AMPLITUDE AND HIGH-FREQUENCY FOCUSED ULTRASOUND WITH LIGHT-ABSORBING MATERIALS

The Regents Of The Univer...

1. A high-frequency light-generated focused ultrasound (LGFU) device, comprising:
a source of light energy; and
an arcuate optoacoustic lens comprising a composite layer that comprises a plurality of light absorbing particles and a dielectric
material having a coefficient of volume thermal expansion greater than or equal to about 1×10?5×K?1; wherein when the light energy is directed to the arcuate optoacoustic lens it is capable of generating focused ultrasound
having a frequency of greater than or equal to about 10 MHz and an output pressure of greater than or equal to about 1 MPa.

US Pat. No. 9,212,180

MENIN-MLL INHIBITORS AND METHODS OF USE THEREOF

THE REGENTS OF THE UNIVER...

1. A composition comprising a compound having the structure of formula I:

wherein Y is independently selected from OH, OR7, NH2, NHR7, or NR7aR7b;

wherein R7 selected from C1-6-alkyl, monohalo-C1-6-alkyl, polyhalo-C1-6-alkyl, (C1-4-alkyloxy)-C1-6-alkyl, (C1-4-dialkylamino)-C1-6-alkyl, C1-4—(C3-6-cycloalkyl), C1-4—(C5-6-heteroaryl), C1-4—(C5-6-aryl), C1-4—OH, C1-4—NH2, and C1-4—CN;

wherein R7a and R7b are selected from C1-6-alkyl, monohalo-C1-6-alkyl, polyhalo-C1-6-alkyl, (C1-4-alkyloxy)-C1-6-alkyl, (C1-4-dialkylamino)-C1-6-alkyl, C1-4—(C3-6-cycloalkyl), C1-4—(C5-6-heteroaryl), C1-4—(C5-6-aryl), C1-4—OH, C1-4—NH2, and C1-4—CN, or may form a ring between R7a and R7b with C3-7 carbons;

wherein R1 is aryl or heteroaryl and substituted with 0, 1, 2, or 3 groups each independently selected from cyano, halo, hydroxyl, C1-3-alkyl, C1-3-alkyloxy, monohalo-C1-3-alkyl, polyhalo-C1-3-alkyl, and sulfonyl-C1-3-alkyl;

wherein R2 is selected from heteroaryl, heterocycle, carbocycle containing a C3-8 ring size, or acyclic C1-6-alkyl;

wherein R2 is substituted with 0, 1, 2, or 3 groups each independently selected from cyano, halo, hydroxyl, C1-3-alkyl, C1-3-alkyloxy, monohalo-C1-3-alkyl, polyhalo-C1-3-alkyl, and sulfonyl-C1-3-alkyl;

wherein A is a 1,4-disubstituted aryl or heteroaryl ring substituted with X and R3 and may contain a third group R6 independently selected from cyano, halo, hydroxyl, C1-3-alkyloxy, monohalo-C1-3-alkyl, polyhalo-C1-3-alkyl, sulfonyl-C1-3-alkyl and sulfonamide;

wherein X is O, NH, or NR8; wherein when X is NR8, R8 may be independently selected from C1-3-alkyl, C1-3-alkyloxy, monohalo-C1-3-alkyl, polyhalo-C1-3-alkyl, and sulfonyl-C1-3-alkyl

wherein R3 is CN, SO2NH2, SO2NR9aR9b, CONR9aR9b, SO2CH3, OCF3, CF3, Cl, CH2CN, CH2NH2, CH2NHC(O)R10, CH2NHSO2R10, NO2, 4-pyridyl, 3-pyridyl, 1,2,3-triazole, OCH3; wherein R9a and R9b may be independently selected from hydrogen, C1-3-alkyl, or polyhalo-C1-3-alkyl, or may form a ring between R9a and R9b with C3-7 carbons; wherein R10 is C1-3-alkyl; or polyhalo-C1-3-alkyl;

wherein R4 is hydrogen, or C1-3-alkyl; and

wherein R5 is hydrogen, OH, or C1-3-alkyl.

US Pat. No. 9,132,411

STRATEGIES, LINKERS AND COORDINATION POLYMERS FOR HIGH-PERFORMANCE SORBENTS

The Regents of the Univer...

1. A coordination polymer defining a molecular framework, the coordination polymer comprising:
a plurality of metal atoms or metal clusters, and
a plurality of organic linking ligands, each linking ligand comprising a residue of a compound having Formula I or VII:

wherein:
R1 and R1? are each independently CO2R2, CONR22, CN, a C2-8 alkynyl, or a C4-18 heteroatom-containing aromatic ring system;

R2 is H, a metal cation, an organic cation, C1-8 alkyl, C1-8 perfluoroalkyl, a C6-18 aromatic ring system, or a C4-18 heteroatom-containing ring system;

A is a substituted or unsubstituted C6-18 aromatic ring system or a C4-18 heteroatom-containing ring system; and

B1, B2, B3 are each independently a substituted or unsubstituted C6-18 aromatic ring system, a C4-18 heteroatom-containing ring system, C7-18 alkyl aryl, or C5-18 alkyl heteroaryl, wherein B1, B2, B3 are distributed about the A moiety.

US Pat. No. 9,126,978

1,4-BENZODIAZEPINE-2,5-DIONES AND RELATED COMPOUNDS WITH THERAPEUTIC PROPERTIES

The Regents of the Univer...

1. A compound described by a formula selected from the group consisting of:
or a pharmaceutically acceptable salt thereof;
wherein R2 is selected from the group consisting of H, alkyl, and substituted alkyl;

wherein R3 is selected from the group consisting of H; alkyl; and OH;

wherein R4 is N;

wherein R5 is selected from the group consisting of H, alkyl, substituted alkyl, mono-substituted aryl, di-substituted aryl, and tri-substituted
aryl;

wherein R6 is N;

wherein R7, R8, R9, and R10 are independently absent or are selected from the group consisting of —H, halogen, —CF3,

—OH, fluoroalkyl, —SO2R28, —SO2N(R7?)2, —OR7?, —N(R7?)2, —CON(R7?)2, —NHCOR7?, —NHSO2R7?, alkyl, mono-substituted alkyl, di-substituted alkyl, tri-substituted alkyl; wherein R7? is selected from the group consisting of halogen, H, alkyl, mono-substituted alkyl, di-substituted alkyl, tri-substituted
alkyl, aryl, mono-substituted aryl, di-substituted aryl, tri-substituted aryl, cycloaliphatic, mono-substituted cycloaliphatic,
di-substituted cycloaliphatic, and tri-substituted cycloaliphatic;
wherein R15, R16, R17, and R18 are C;
wherein R25, R26, R27, and R28 are independently selected from the group consisting of hydrogen, alkyl,
wherein no more than three of R25, R26, R27, and R28 can be hydrogen;
wherein the stereochemical configuration at a stereocenter in said compound is R, S, or a mixture thereof;
wherein each substituted alkyl, substituted cycloaliphatic, or substituted aryl independently has at least one of the hydrogen
atoms replaced by a halogen, an amino, a hydroxy, a nitro, a lower aliphatic, an aryl, or a cycloaliphatic.

US Pat. No. 9,376,979

FUEL GOVERNOR FOR CONTROLLED AUTOIGNITION ENGINES

Robert Bosch GmbH, Stutt...

1. A method for controlling combustion performance of an engine, the method comprising:
determining a desired fuel quantity for a first combustion cycle;
determining whether one or more engine actuator settings required during a subsequent combustion cycle to cause the engine
to approach a target combustion phasing will be within a defined acceptable operating range if the desired fuel quantity is
injected during the first combustion cycle;

when the one or more engine actuator settings required during a subsequent combustion cycle to cause the engine to approach
a target combustion phasing are predicted to be within the defined acceptable operating range if the desired fuel quantity
is injected during the first combustion cycle, injecting the desired fuel quantity during the first combustion cycle; and

when the one or more engine actuator settings required during a subsequent combustion cycle to cause the engine to approach
a target combustion phasing are predicted to be outside the defined acceptable operating range if the desired fuel quantity
is injected during the first combustion cycle,

determining an attenuated fuel quantity, and
injecting the attenuated fuel quantity during the first combustion cycle.

US Pat. No. 9,304,280

COMPACT LENS SYSTEM AND ARRAY

The Regents Of The Univer...

1. A compact lens system for imaging a sample, said compact lens system comprising:
a substrate having a well defining a first open portion having a first diameter and a second open portion having a second
diameter, said second open portion being concentric with said first open portion and in communication therewith, said second
diameter being less than said first diameter defining an edge therebetween;

a transparent member adjacent said second open portion of said substrate, said transparent member enclosing said second open
portion of said well;

an index matching material being disposed in said well;
a lens member being disposed in at least a portion of said first open portion and said second open portion of said well and
in optical contact with said index matching material disposed in said well, a refractive index of said lens member being generally
equal to a refractive index of said index matching material; and

a spacer member extending from at least one of said substrate and said transparent member to define a spacing from a focal
point of said lens member,

wherein said lens member and said index matching material cooperate to image a sample disposed below said transparent member.
US Pat. No. 9,200,265

ANTI-COCAINE COMPOSITIONS AND TREATMENT

The Trustees of Columbia ...

1. An isolated mutant cocaine esterase (CocE) polypeptide comprising
an amino acid sequence at least 90% identical to SEQ ID NO: 1, having at least one substitution, addition or deletion,
wherein
the at least one substitution, addition or deletion is selected from the group consisting of L163V; V225I; I218L; A310D; A149S;
S159A; S265A; S56G; W220A; S140A; F189L; A193D; T254R; N42V; V262L; L508G; Y152H; V160A; T172R; Y532F; T74S; W285T; L146P;
D533S; A194R; G173Q; C477T; K531A; R41I; L119A; K46A; F84Y; T172R-G173Q; L169K; F189A; N197K; R182K; F189K; V190K; Q191K;
A194K; I175-G-G-A186; and T176-G-G-D185; and

the mutant CocE polypeptide has esterase activity.
US Pat. No. 9,192,650

METHODS OF INHIBITING PHOTORECEPTOR APOPTOSIS BY ELICITING THE FAIM2 ANTIAPOPTOTIC PATHWAY

The Regents of the Univer...

1. A method of increasing photoreceptor survival comprising administering to the retina of a subject a nucleic acid encoding
a polypeptide or peptide with at least 90% identity to SEQ ID NO: 1 (wild-type Fas apoptotic inhibitory molecule 2 (Faim2))
that elicits the Faim2 antiapoptotic pathway.

US Pat. No. 9,297,755

ICE AND SUPERCOOLED WATER DETECTION SYSTEM

The Regents Of The Univer...

1. A system for detecting ice and/or water within an area of interest, said system comprising:
a detection system measuring radiance level of the area of interest when exposed to shortwave infrared (SWIR) radiation having
a wavelength in the range of about 2.05 ?m to about 2.30 ?m, said detection system measuring said radiance level in a first
band having a wavelength in the range of about 2.05 ?m to about 2.15 ?m and outputting a first band signal, said detection
system measuring said radiance level in a second band having a wavelength in the range of about 2.15 ?m to about 2.30 ?m and
outputting a second band signal; and

a processing unit determining a radiance ratio of said first band signal and said second band signal, said processing unit
comparing said radiance ratio to predetermined critical ratio ranges and outputting a determination signal indicating at least
one of presence of ice when said radiance ratio is within a first range of said predetermined critical ratio ranges and presence
of water when said radiance ratio is within a second range of said predetermined critical ratio ranges.

US Pat. No. 9,287,614

MICROMACHINED MILLIMETER-WAVE FREQUENCY SCANNING ARRAY

The Regents Of The Univer...

1. A frequency scanning antenna array comprising:
a rectangular waveguide having an array of slots formed on a wall of the rectangular waveguide serving as radiating elements
operating at millimeter or smaller wave frequency,

wherein said antenna array provides about 2° beam width in an azimuth direction and about 30° beam width in an elevation direction
and is frequency scanning from ?25° to +25 °,

wherein said rectangular waveguide is a micro-machined meander waveguide having dispersive properties that permit beam scanning
by stepping in frequency.

US Pat. No. 9,066,997

SCAFFOLDS AND METHODS OF FORMING THE SAME

The Regents of The Univer...

1. A scaffold, comprising:
a tubular polymeric structure having: an outer cylindrical wall; and an inner cylindrical wall defining a longitudinal bore
therethrough;

a controlled gradient of a plurality of solid-walled microtubules oriented radially between the outer cylindrical wall and
the inner cylindrical wall in the tubular polymeric structure; and

a controlled gradient of a plurality of radially oriented microtubule pores, each pore defined between an adjacent pair of
solid-walled microtubules;

wherein:
an average pore size of each of the plurality of microtubule pores decreases from the inner cylindrical wall of the tubular
polymeric structure to the outer cylindrical wall of the tubular polymeric structure; or

an average pore size of each of the plurality of microtubule pores decreases from the outer cylindrical wall of the tubular
polymeric structure to the inner cylindrical wall of the tubular polymeric structure;

and wherein the controlled gradients of the plurality of solid-walled microtubules and the plurality of radially oriented
microtubule pores are formed using a multi-directional, radially oriented temperature gradient.

US Pat. No. 9,487,579

METHODS AND COMPOSITIONS FOR MODULATION OF BLOOD-NEURAL BARRIER

LUDWIG INSTITUTE FOR CANC...

1. A method for treating neural edema in a higher vertebrate animal in need of such treatment comprising administering to
said animal an effective amount of an anti-PDGF-CC antibody or an anti-PDGF-C antibody.

US Pat. No. 9,403,856

BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME

THE REGENTS OF THE UNIVER...

1. A compound selected from the group consisting of

US Pat. No. 9,353,129

MICROPOROUS COORDINATION COMPLEX AND METHOD OF MAKING THE SAME

The Regents Of The Univer...

1. A three-dimensional coordination complex comprising:
a plurality of inorganic centers;
a plurality of a first bis(bidentate) linker having a first length and two bidentate binding sites; and
a plurality of a second bis(bidentate) linker having a second length and two bidentate binding sites,
wherein each of the first and the second bis(bidentate) linkers is selected from the group consisting of:

with the following provisos that where the first or second bis(bidentate) linker has the structure of:
(i) Formula (A), the other linker has the structure of Formula (B);
(ii) Formula (B), the other linker has the structure of Formula (A) or (C);
(iii) Formula (C), the other linker has the structure of Formula (B), (D), or (D?);
(iv) Formula (D) or (D?), the other linker has the structure of Formula (C), (E), or (F);
(v) Formula (E) or (F), the other linker has the structure of Formula (D), (D?), or (G);
(vi) Formula (G), the other linker has the structure of Formula (E), (F) or (H); and,
(vii) Formula (H), the other linker has the structure of Formula (G).

US Pat. No. 9,065,067

STACKED WHITE OLED HAVING SEPARATE RED, GREEN AND BLUE SUB-ELEMENTS

The Regents of the Univer...

1. An organic light emitting device comprising in order:
a cathode;
a blue-emitting sub-element comprising an emissive layer comprising a phosphorescent blue emissive material;
a charge-generating layer;
a green-emitting sub-element comprising an emissive layer comprising a phosphorescent green emissive material;
a charge-generating layer;
a red-emitting sub-element comprising an emissive layer comprising a phosphorescent red emissive material;
and an anode;
wherein a combined emission of the emissive materials gives a white emission from the device.
US Pat. No. 9,393,548

RAPID AND ENHANCED ACTIVATION OF MICROPOROUS COORDINATION POLYMERS BY FLOWING SUPERCRITICAL CO2

The Regents Of The Univer...

1. A method for treating a solvent-containing metal organic framework material (MOF) to increase its internal surface area
or porosity, comprising introducing a composition consisting of CO2 into a vessel containing the solvent-containing MOF, while venting the CO2 and maintaining supercritical conditions for carbon dioxide in the vessel.

US Pat. No. 9,362,719

GAN-BASED QUANTUM DOT VISIBLE LASER

THE REGENTS OF THE UNIVER...

1. A laser comprising:
a contact layer structure for injecting conduction carriers into an active region of the laser;
a semiconductor optical waveguide structure;
a laser cavity; and
a GaN-based quantum dot layer structure within the laser cavity and configured as the active region of the laser, the quantum
dot layer structure comprising at least one layer of quantum dots each positioned and sized in a self-organizing manner to
produce (i) an array of self-organized quantum dots extending the entire at least one layer and characterized by strain relaxation
induced from the self-organizing and (ii) a laser emission having a wavelength of 490 nm-570 nm from the laser cavity structure
and the quantum dot layer structure being configured to produce, in response to injection of the conduction carriers into
the active region via the contact layer structure, the laser emission having a linewidth of 1 nm or smaller, the at least
one layer of quantum dots exhibiting an wavelength shift on the laser emission of no more than about 5 nm over a range of
injection currents from an initial injection current to a threshold current of the at least one layer of quantum dots, wherein
the laser is characterized by a threshold injection current density of 1.2 kA/cm2.

US Pat. No. 9,285,375

COMPOSITIONS AND METHODS FOR DETECTING AND TREATING NEUROLOGICAL CONDITIONS

The Regents of the Univer...

1. A method of detecting the presence of a NIPA-1 nucleic acid encoding a T45R NIPA-1 mutation in a sample, comprising: (a)
contacting a NIPA-1 nucleic acid in a sample under stringent conditions with a detectably labeled oligonucleotide that specifically
hybridizes to a NIPA-1 nucleic acid at a sequence comprising a G at a position corresponding to position 134 of SEQ ID NO:
1; and (b) detecting hybridization of the oligonucleotide with the NIPA-1 nucleic acid, wherein detection of hybridization
is indicative of the presence of a NIPA-1 nucleic acid encoding a T45R NIPA-1 mutation in the sample.

US Pat. No. 9,150,581

NICOTINIC RECEPTOR COMPOUNDS

RESEARCH TRIANGLE INSTITU...

1. A compound represented by formula (I)

wherein X is H and Y is —SO2CH3, —SO2NH2, or —SO2CF3; or X is —SO2CH3, —SO2NH2, or —SO2CF3, and Y is H; or a pharmaceutically acceptable salt thereof.

US Pat. No. 9,056,951

ULTRASTRONG AND STIFF LAYERED POLYMER NANOCOMPOSITES AND HIERARCHICAL LAMINATE MATERIALS THEREOF

THE REGENTS OF THE UNIVER...

1. A layered polymer nanocomposite comprising:
a nanosheet laminate having a first layer and a second layer, said first layer being made of a first material comprising poly(vinyl
alcohol) (PVA) and said second layer being made of a second material comprising an aluminosilicate nanoparticle, wherein said
first material and said second material have a chemical affinity for each other, wherein the first layer comprising PVA is
cross-linked by exposure to a cross-linking agent selected from the group consisting of: manganese ions (Mn+) and copper ions (Cu2+) to form an ultrastrong nanosheet laminate.

US Pat. No. 9,216,993

COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF

THE REGENTS OF THE UNIVER...

3. A method for the treatment of leukemia comprising administering a compound of claim 1 to a subject suffering from leukemia.

US Pat. No. 9,182,371

MICROSCALE WESTERN BLOT

The Regents Of The Univer...

1. A capillary electrophoresis and blotting system comprising:
an electrophoresis component comprising a separation capillary having proximal and distal ends, the separation capillary operable
to be filled with a sieving medium and electrophorese a sample from the proximal end to the distal end;

a blotting component comprising a surface;
a translating component operable to change position of the distal end of the separation capillary relative to the surface
of the blotting component, wherein the distal end of the separation capillary and the surface of the blotting component are
operable to be electrically coupled during electrophoresis of the sample; and

a buffer capillary having proximal and distal ends, the distal end of the buffer capillary located proximate to the distal
end of the separation capillary, wherein the buffer capillary is operable to be filled with electrophoresis buffer or gel
to electrically couple the distal end of the separation capillary and the surface of the blotting component during electrophoresis
of the sample.

US Pat. No. 9,096,501

PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM

THE REGENTS OF THE UNIVER...

1. A compound of formula (XXII):

wherein:
n=1 to 5;
R1 to R4 are H; and

R5 and R6 are independently selected from the group consisting of H, methyl, ethyl, n-prolyl, iso-prolyl, n-butyl, iso-butyl, tert-butyl,
phenyl, tolyl, benzyl.

US Pat. No. 9,347,929

CONTROLLING TRANSLOCATION THROUGH NANOPORES WITH FLUID WALL

The Regents Of The Univer...

1. A method of detecting, quantifying, or characterizing a biomolecule, collection of biomolecules, or particles using the
Coulter principle, comprising:
providing a transit path for biomolecules to pass through a nanopore from a first liquid compartment to a second liquid compartment,
wherein the first and second liquid compartments contain electrodes disposed to measure voltage difference, current flow,
or resistance between the first and second liquid compartments; and

measuring voltage difference, current flow, or resistance between the first and second liquid compartments over time as individual
biomolecules pass through the nanopore;

wherein the nanopore is a passageway through a substrate, which passageway is lined with a fluid lipid coating, and
wherein the nanopore is characterized by a nominal width perpendicular to the transit path that is about 1.5 to about 50 times
the dimension of the biomolecule or particle and wherein the length of the nanopore parallel to the transit path is one to
five times its nominal width,

and wherein the passageway lined with the fluid lipid coating provides the transit path.
US Pat. No. 9,284,594

COMPOSITIONS AND METHODS RELATING TO FUSION PROTEIN BIOMARKERS

THE REGENTS OF THE UNIVER...

1. A method for characterizing a biological sample, comprising:
a) providing:
a biological sample, wherein said biological sample is a blood sample and/or a tissue sample,
one or more distinct groups of labeled peptides, wherein each distinct group of labeled peptides is specific for a particular
fusion protein to be detected, wherein the labeled peptides within each distinct group have labeled peptides having an amino
acid sequence that spans the fusion junction of said particular fusion protein encoded by a fusion of a first nucleic acid
to a second nucleic acid,

wherein said labeled peptides within each distinct group comprise peptides having one isotopically labeled amino acid residue
and peptides having two isotopically labeled amino acid residues,

wherein said amino acid sequence of said labeled peptides within each distinct group is identical with an amino acid sequence
of a particular fusion protein peptide fragment generated through digestion of said particular fusion protein with a protease,

one or more proteases known to generate upon digestion of said one or more fusion proteins to be detected particular fusion
protein peptide fragments,

b) digesting said biological sample with said one or more proteases resulting in generation of biological sample-based peptide
fragments,

c) combining said one or more distinct groups of labeled peptides with said generated biological sample-based peptide fragments,
d) purifying said labeled peptides combined with said generated biological sample-based peptide fragments,
e) conducting a multiple reaction monitoring mass-spectrometry (MRM-MS) analysis of said purified biological sample-based
peptide fragments combined with said labeled peptides, and

f) analyzing the results of said MRM-MS analysis, wherein said analyzing comprises detecting the presence or absence of a
biological sample-based fusion protein peptide fragment having an amino acid sequence identical with the amino acid sequence
for one of the distinct groups of labeled peptides specific for a particular fusion protein,

wherein detected co-elution of
i) a biological sample-based fusion protein peptide fragment having an amino acid sequence identical with the amino acid sequence
for one of the distinct groups of labeled peptides specific for a particular fusion protein, and

ii) said amino acid sequence for one of the distinct groups of labeled peptides specific for a particular fusion protein,
indicates the presence of said particular fusion protein within said biological sample.

US Pat. No. 9,231,546

MULTI-DIMENSIONAL ARRAY OF IMPEDANCE ELEMENTS

The Regents of the Univer...

1. Circuitry comprising:
a multi-dimensional array of impedance elements; and
decoder circuitry configured to decode a selection signal to select a variable number of impedance elements within said array
for connection in parallel, wherein

said impedance elements have a sequence and said selection signal selects a plurality of adjacent impedance elements within
said sequence to be connected together in parallel as a selected sequence, and

said selection signal selects a start point of said selected sequence and an end point of said selected sequence.

US Pat. No. 9,128,093

SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF

THE REGENTS OF THE UNIVER...

1. A method for processing a leukocyte contained within a body fluid from a subject with acute lung injury (ALI) or acute
respiratory distress syndrome (ARDS), the method comprising:
(a) sequestering extracorporeally a primed or activated leukocyte; and
(b) treating the leukocyte sequestered during step (a) with a calcium chelating agent to inhibit release of a pro-inflammatory
substance from the leukocyte or to deactivate the leukocyte.

US Pat. No. 9,062,093

PEPTIDE COMPOSITIONS AND METHODS FOR TREATING PATIENTS

THE REGENTS OF THE UNIVER...

1. A method for treating a condition comprising administering to a patient an effective amount of a composition, wherein the
composition comprises:
at least one peptide consisting of the amino acid sequence GGL, GLG, LGL, LLG, LGG, GLL, GGdL, GdLG, GdLL, GLdL, GdLdL, dLLG,
LdLG, dLdLG, dLGG, dLGL, LGdL, or dLGdL, or a pharmaceutically acceptable salt of the peptide;

at least one peptide consisting of the amino acid sequence GGL, GLG, LGL, LLG, LGG, GLL, GGdL, GdLG, GdLL, GLdL, GdLdL, dLLG,
LdLG, dLdLG, dLGG, dLGL, LGdL, or dLGdL, or a pharmaceutically acceptable salt of the peptide, wherein the peptide is acetylated
at the N-terminus;

at least one peptide consisting of the amino acid sequence GGL, GLG, LGL, LLG, LGG, GLL, GGdL, GdLG, GdLL, GLdL, GdLdL, dLLG,
LdLG, dLdLG, dLGG, dLGL, LGdL, or dLGdL, or a pharmaceutically acceptable salt of the peptide, wherein the peptide is amidated
at the C-terminus; or

at least one peptide consisting of the amino acid sequence GGL, GLG, LGL, LLG, LGG, GLL, GGdL, GdLG, GdLL, GLdL, GdLdL, dLLG,
LdLG, dLdLG, dLGG, dLGL, LGdL, or dLGdL, or a pharmaceutically acceptable salt of the peptide, wherein the peptide is acetylated
at the N-terminus and amidated at the C-terminus; and

wherein the condition is prediabetes, diabetes, obesity, high blood pressure, metabolic syndrome, poor glycemic control, or
reduced insulin secretion.

US Pat. No. 9,385,348

ORGANIC ELECTRONIC DEVICES WITH MULTIPLE SOLUTION-PROCESSED LAYERS

The Regents of the Univer...

1. A method for fabricating an organic light emitting device stack, the method comprising:
(a) depositing a first conductive electrode layer over a substrate;
(b) depositing a first set of one or more organic layers, wherein at least one of the first set of organic layers is a first
emissive layer and one of the first set of organic layers is deposited by a solution-based process that utilizes a first solvent;

(c) depositing a first conductive interlayer by a dry deposition process; and
(d) depositing a second set of one or more organic layers, wherein at least one of the second set of organic layers is a second
emissive layer and one of the second set of organic layers is deposited by a solution-based process that utilizes a second
solvent, wherein all layers that precede the layer deposited using the second solvent are insoluble in the second solvent.

US Pat. No. 9,373,742

PLASMA-ASSISTED TECHNIQUES FOR FABRICATING SEMICONDUCTOR DEVICES

The Regents Of The Univer...

1. A method for fabricating a semiconductor device having a p-n junction, comprising:
forming one or more protrusions on a top surface of an ingot using photolithographic techniques, where the ingot is comprised
of a multi-layer structure of atomically thin two-dimensional sheets;

doping the one or more protrusions by applying a plasma thereto; and
exfoliating layers of a given protrusion from the top surface of the ingot by pressing the top surface of the ingot against
a planar surface of a bottom electrode.

US Pat. No. 9,289,140

SYSTEMS AND METHODS FOR IMAGING CHANGES IN TISSUE

THE REGENTS OF THE UNIVER...

1. A computer-based method for generating a parametric response map comprising:
a) obtaining a first set of parametric measurement data for a tissue region with an imaging device, the first set of parametric
measurement data comprising a plurality of voxels; b) administering a treatment to the tissue region;

c) obtaining one or more subsequent sets of parametric measurement data, each subsequent set of parametric measurement data
comprising a plurality of voxels, and the subsequent sets of parametric measurement data being obtained with the imaging device
or another imaging device;

d) registering the one or more subsequent sets of parametric response data with the first set of parametric response data;
and

e) identifying, on a voxel-by-voxel basis, whether the voxels within the tissue region have increased, decreased, or unaltered
parametric measurement properties, using a defined threshold, wherein each of the changes is determined by comparing voxels
of the one or more subsequent sets of parametric measurement data to the voxels of one or more subsequent sets of parametric
measurement data obtained previously or to the voxels of the first set of parametric measurement data.

US Pat. No. 9,213,889

ATHLETE SPEED PREDICTION METHOD USING DATA FROM ATTACHED INERTIAL MEASUREMENT UNIT

The Regents Of The Univer...

7. The method according to claim 1 wherein said attaching said inertial measurement unit to the subject comprises attaching an inertial measurement unit to
a neck of the subject.

US Pat. No. 9,388,498

ELECTROCHEMICAL LIQUID-LIQUID-SOLID DEPOSITION PROCESSES FOR PRODUCTION OF GROUP IV SEMICONDUCTOR MATERIALS

The Regents Of The Univer...

1. A method comprising:
contacting a liquid electrolyte with a first liquid electrode, wherein the first liquid electrode is in electrical communication
with a second electrode having a second opposite polarity from the first liquid electrode, wherein the liquid electrolyte
is formed by combining water and an oxide compound of a semiconductor element selected from the group consisting of: silicon,
germanium, and combinations thereof, and wherein the first liquid electrode comprises a metal selected from the group consisting
of: mercury, gallium, indium, zinc, cadmium, combinations and alloys thereof; and

generating a precipitated crystalline solid material comprising the semiconductor element by applying an electric potential
to the first liquid electrode in contact with the electrolyte to drive an electrochemical reduction reaction that forms a
solid material comprising the semiconductor element by precipitation out of solution at or within the first liquid electrode.

US Pat. No. 9,279,739

VIRTUAL NONCONTACT EXCITATION

The Regents of the Univer...

1. An excitation system comprising:
a pair of piezoelectric elements configured to apply respective excitation forces to a test structure;
a clamp comprising an adjustable arm, the adjustable arm being configured to capture the test structure between the pair of
piezoelectric elements;

a controller coupled to the pair of piezoelectric elements and configured to generate a respective excitation control signal
for each piezoelectric element, each excitation control signal being configured such that the respective excitation forces
are matched to one another; and

a pair of sensor film structures to generate respective output signals indicative of the excitation forces applied to the
test structure, each sensor film structure being disposed between a respective one of the pair of piezoelectric elements and
the test structure.

US Pat. No. 9,282,326

INTERACTIVE CAMERA CALIBRATION TOOL

The Regents Of The Univer...

1. A computer-assisted method for calibrating a camera, comprising:
(a) initializing parameters of a camera model using image data of a calibration target captured by a camera, where the camera
model defines a relationship between an image captured by the camera and a corresponding image without any distortion caused
by the camera;

(b) predicting parameters of the camera model for each of a plurality of candidate target positions, thereby yielding an estimated
camera model for each of the plurality of candidate target positions;

(c) determining a certainty measure for each of the estimated camera models;
(d) selecting a target position from the plurality of candidate target positions, where the selected target position resulted
in the estimated camera model having the smallest certainty measure;

(e) presenting the selected target position on a display device;
(f) capturing, by the camera, image data of the calibration target while the calibration target is positioned proximate to
the selected target position;

(g) computing parameters of the camera model using the image data captured by the camera of the calibration target while the
calibration target is positioned proximate to the selected target position; and

(h) determining a certainty measure for the camera model using the computed parameters of the camera model.

US Pat. No. 9,261,753

SPECTRUM FILTERING FOR VISUAL DISPLAYS AND IMAGING HAVING MINIMAL ANGLE DEPENDENCE

The Regents Of The Univer...

1. An optical spectrum filtering device comprising:
an interference filter assembly comprising a dielectric material having a refractive index of greater than about 1.5 disposed
between a pair of parallel reflective surfaces; wherein the filter assembly is capable of transmitting a portion of an electromagnetic
spectrum to generate a filtered output having a predetermined range of wavelengths that displays minimal angle dependence
so that the predetermined range of wavelengths varies less than or equal to about 50 nm from an incidence angle of 0 to an
incidence angle of 90°.

US Pat. No. 9,242,087

NANOCOMPOSITES FOR NEURAL PROSTHETICS DEVICES

The Regents Of The Univer...

1. An implantable electrically conductive device comprising:
a flexible, electrically conductive, implantable region that comprises a nanocomposite material comprising a plurality of
nanoparticles selected from the group consisting of: gold nanoparticles, carbon nanotubes, and combinations thereof.

US Pat. No. 9,221,757

PROCESS FOR FLUORINATING COMPOUNDS

The Regents of the Univer...

1. A method of preparing a fluorinated heteroaryl substrate, comprising: mixing potassium fluoride, one or more imidazolium
salts, a solvent, and a substrate having Formula IA or IB:

wherein
A is Cl, Br, SO2R8, or NO2;

B is H, Cl, Br, SO2R8, or NO2;

C is H, Cl, Br, SO2R8, or NO2;

R1 is H, CN, or CO2R8, wherein each R8 is, independent of any other, optionally substituted C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, heterocycloalkyl, heteroaryl, cycloalkyl, or aryl; and

R2 is H, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl.

US Pat. No. 9,211,110

LUNG VENTILLATION MEASUREMENTS USING ULTRASOUND

THE REGENTS OF THE UNIVER...

1. A method of determining change in volume of a target sample, the method comprising:
receiving, at an imaging processing machine, ultrasound images of a two-dimensional area corresponding to the target sample,
where a first ultrasound image is taken at a first time period and a second ultrasound image is taken at a second time period
after the first time period;

determining, at the imaging processing machine, a change in strain value of the target sample over the two-dimensional area,
wherein the strain value is determined from comparing the first ultrasound image to the second ultrasound image, wherein the
first ultrasound image and the second ultrasound image are speckle-containing images;

determining, at the imaging processing machine, and from the change in strain value, an xy-plane change in area of the target
sample between the first time period and the second time period;

determining, at the imaging processing machine, an approximate physical z-axis displacement over the two-dimensional area
by approximating a change in local curvature of the two-dimensional area between the first time period and the second time
period; and

determining, at the imaging processing machine, a volume displacement of the target sample from the approximate physical z-axis
displacement and change in strain value.

US Pat. No. 9,132,447

APPARATUS AND METHOD FOR DEPOSITION FOR ORGANIC FILMS

The Regents of the Univer...

1. An organic continuum vapor deposition system, comprising:
a heated chamber, wherein all walls of the chamber are heated;
a cooled substrate with the chamber, having a coating surface;
a source cell located at a back plate of the chamber and having an output opening directed into the heated chamber;
a valve within the source cell;
an organic material source;
a heater configured to provide sufficient heat to convert the organic material into an organic vapor, the heater being configured
to provide the heat through at least the back plate of the chamber; and

at least one carrier gas source; wherein
the heated chamber has a temperature sufficiently high to provide diffusive mixing of the gas and vapor from the source cell
to provide a uniform organic flux of the organic vapor, above the cooled substrate, thereby depositing a substantially uniform
film of the organic material on the coating surface of the cooled substrate;

wherein the source cell is positioned through the back plate of the chamber, and
wherein the valve comprises a bypass line that is open when the valve is closed, and closed when the valve is open.

US Pat. No. 9,097,183

RAYLEIGH-TAYLOR ASSISTED COMBUSTION AND COMBUSTORS ADAPTED TO EXPLOIT RAYLEIGH-TAYLOR INSTABILITY FOR INCREASING COMBUSTION RATES THEREIN

THE REGENTS OF THE UNIVER...

6. An engine comprising:
an annular combustor that extends axially in which a fuel and oxidizer reactant mixture and combustion product gases are subjected
to acceleration directed transverse to a direction along which the reactant mixture flows through said combustor during combustion;

a plurality of catalyst elements defined as catalyst material having a longer dimension oriented generally parallel to a streamwise
direction along which the reactant mixture and product gases flow through said combustor and on a radially outermost inner
surface of said combustor that is perpendicular to the direction of the transverse acceleration to generate Rayleigh-Taylor
instability between the product gases and the reactant mixture present in said combustor during combustion to thereby enhance
interpenetration of the reactant mixture and product gases within the combustor chamber; and

wherein said catalyst elements are positioned in said combustor and arranged circumferentially around said combustor with
circumferential separations between two adjacent of said catalyst elements along a lateral direction that is perpendicular
to the transverse direction along which the acceleration acts on the gases flowing through said combustor during combustion.

US Pat. No. 9,083,392

WIRELESS SENSING AND COMMUNICATION UTILIZING RF TRANSMISSIONS FROM MICRODISCHARGES

THE REGENTS OF THE UNIVER...

1. A system capable of RF communication, the system comprising:
a supply to produce an electrical supply signal;
a device coupled to the supply to receive the electrical supply signal and comprising a plurality of microfabricated electrodes
spaced to generate an electrical microdischarge in a medium and in response to the supply signal, wherein the generated electrical
microdischarge generates an RF transmission in response to variations in one or both of (i) the supply signal and (ii) characteristics
of the medium; and,

an antenna to receive the RF transmission from the electrical microdischarge to enable the RF communication,
wherein the microfabricated electrodes of the device form a sensor of the device, the sensor having a state such that the
RF transmission generated by the electrical microdischarge is indicative of the sensor state, and wherein the sensor indicates
whether a chemical species is present in the medium via a modification of a characteristic of the RF transmission resulting
from an interaction between the electrical microdischarge and the chemical species.

US Pat. No. 9,389,983

VERIFICATION OF COMPLEX SYSTEMS THAT CAN BE DESCRIBED BY A FINITE STATE TRANSITION SYSTEM

The Regents of the Univer...

1. A computer-implemented method of verifying a hardware design of an electronic circuit comprising control logic which controls
manipulation of data, said method comprising the steps of:
receiving a description of said hardware design of said electronic circuit in a computer; generating, based on said description
in said computer a model of said hardware design of said electronic circuit said model comprising an initial state function
defining at least one initial state, a transition function defining how said hardware design moves between consecutive states
and a property function defining a property that should be met for an allowable state, said initial state function, transition
function and property function each comprising at least one of data, operations and predicates;

generating an abstracted model defining data defining an abstracted model of said hardware design by approximating at least
some of said data, operations and predicates with uninterpreted terms, uninterpreted functions and uninterpreted predicates
respectively, the abstracted model defining data comprising an abstracted initial state function defining at least one abstracted
initial state, abstracted transition function and abstracted property function within said abstracted model;

performing a reachability analysis in the computer on said abstracted model to determine whether when starting from said at
least one abstracted initial state, said hardware design can reach an unallowable abstracted state by following said abstracted
transition function; and

if said hardware design cannot reach an unallowable abstracted state, said hardware design is verified as correct; and
if said hardware design can reach an unallowable abstracted state, unabstracting a trace of said transitions from said at
least one abstracted initial state to said unallowable abstracted state and determining using said model whether steps of
said unabstracted trace are feasible; and

if steps of said unabstracted trace are not feasible, updating the abstracted model defining data to refine said abstracted
model to preclude any infeasible steps and repeating said reachability analysis on said refined abstracted model; and

if steps of said unabstracted trace are feasible, generating an error;
wherein the reachability analysis comprises:
determining whether each of the at least one abstracted initial state is an allowable state, and if not, determining that
said hardware design can reach an unallowable state;

determining whether, when starting from said at least one abstracted initial state, said hardware design can reach an unallowable
abstracted state in one transition of the abstracted transition function, and if so, determining that said hardware design
can reach an unallowable state; and

without determining all reachable states that can be reached from said at least one abstracted initial state by following
said abstracted transition function and without unrolling the abstracted transition function, determining whether the allowable
states include at least one counter example to induction (CTI) state which is an allowable state from which an unallowable
state can be reached in one transition of the abstracted transition function, and if said at least one CTI state is reachable
from the at least one abstracted initial state by following the abstracted transition function, then determining that said
CTI state is a counter example to induction and that said hardware design can reach an unallowable state.

US Pat. No. 9,384,905

HIGH PERFORMANCE TRANSITION METAL CARBIDE AND NITRIDE AND BORIDE BASED ASYMMETRIC SUPERCAPACITORS

The Regents of the Univer...

1. An asymmetric supercapacitor comprising:
a first electrode comprising a first active material and having a first operating window, wherein the first active material
comprises a material selected from the group consisting of a metal oxynitride, a metal oxycarbide, a metal oxyboride, and
combinations thereof, and the metal is selected from the group consisting of Groups III, IV, V, VI, or VII of the Periodic
Table;

a second electrode comprising a second active material and having a second operating window, wherein the first and second
operating windows overlap by 0%, based on voltage;

a separator disposed between the first and second electrodes; and
an aqueous electrolyte.

US Pat. No. 9,341,604

DEVICES AND METHODS FOR ADAPTIVE MICRO-GAS CHROMATOGRAPHY

The Regents Of The Univer...

19. An adaptive micro-gas chromatography device, comprising:
a first micro-gas chromatographic column, wherein the first micro-gas chromatographic column receives a sample comprising
one or more target analytes; and

a modulator component assembly disposed downstream of and in fluid communication with the first micro-gas chromatographic
column, which regulates fluid flow into a plurality of downstream micro-gas chromatographic columns in fluid communication
therewith, the plurality of downstream micro-gas chromatographic columns in provided in parallel to one another, wherein the
modulator component assembly comprises a first on-column detector for detecting the presence of one or more target analytes
eluted from the first micro-gas chromatographic column and a thermal injector device, wherein the adaptive micro-gas chromatography
device further comprises an additional detector for each respective downstream micro-gas chromatographic column so as to detect
the presence of one or more target analytes eluted therefrom; wherein the first on-column detector generates an output received
by the modulator component assembly to regulate fluid flow into the respective downstream micro-gas chromatographic columns.

US Pat. No. 9,144,694

LESION GENERATION THROUGH BONE USING HISTOTRIPSY THERAPY WITHOUT ABERRATION CORRECTION

THE REGENTS OF THE UNIVER...

1. A method of treating tissue with ultrasound energy, comprising:
positioning a focus of a histotripsy transducer on a target tissue;
delivering histotripsy energy from the histotripsy transducer through a bone aberrator;
forming a histotripsy bubble cloud on the focus; and
preventing the formation of secondary histotripsy bubble clouds due to the bone aberrator without implementing an aberration
correction algorithm; and

in the event that a secondary histotripsy bubble cloud develops away from the focus due to the bone aberrator, decreasing
a power level of the histotripsy transducer until the secondary bubble cloud disappears.

US Pat. No. 9,135,011

NEXT BRANCH TABLE FOR USE WITH A BRANCH PREDICTOR

The Regents of the Univer...

1. Apparatus for processing data comprising:
instruction decoding circuitry configured to decode program instructions, each having an instruction address, to generate
control signals for controlling data processing circuitry to perform data processing operations specified by said program
instructions;

branch prediction circuitry configured to perform a prediction of a branch outcome of a branch instruction in dependence upon
at least an instruction address of said branch instruction; and

next branch table circuitry configured to store data identifying for given instruction address in a computer program flow
a next branch instruction address of a next branch instruction following said given instruction address within a current pass
through said computer program flow; wherein

said next branch table circuitry is configured to supply said next branch instruction address to said branch prediction circuitry
before said instruction decoding circuitry identifies said next branch instruction as a branch instruction during said current
pass; and

said branch prediction circuitry is configured to use said next branch instruction address received from said next branch
table circuitry to commence prediction of a next branch outcome of said next branch instruction before said instruction decoding
circuitry decodes said next branch instruction during said current pass.

US Pat. No. 9,427,164

INSERTABLE NEURAL PROBE WITH FLEXIBLE STRUCTURE

The Regents of the Univer...

1. A neural probe (10), comprising:
a body (14), a tip (16), and a shank (12) extending from the body (14) to the tip (16), the tip (16) comprising a plurality of branches (20), wherein each branch (20) extends straight from the shank (12) to a respective branch end (22) at a non-perpendicular angle with respect to the shank (12), and at least one branch (20) of the plurality of branches is located at the same lengthwise portion of the shank (12) as another branch (20) of the plurality of branches;

one or more electrodes (24) supported by the tip (16) for stimulating neurons, recording neural electrical activity, or both; and

a biodegradable coating (18) disposed over the tip (16), the coating (16) having a stiffness that is higher than a stiffness of the shank (12).

US Pat. No. 9,389,184

TWO-PHOTON ENDOSCOPIC SCANNING ASSEMBLY FOR INFLAMMATORY DISEASE DETECTION

THE REGENTS OF THE UNIVER...

1. A method of detecting a biomarker within a 3-dimensional volume of a sample, the method comprising:
providing an endoscopic assembly for producing an output laser energy, the endoscopic assembly comprising an xy scanning stage
and an actuator stage for z-axis scanning within the sample;

the xy scanning stage scanning the output laser beam over a planar scan area of the sample;
the actuator stage scanning the output laser beam over a depth range of the sample, where the depth range and the planar scan
area form the 3-dimensional volume, driving the actuator stage using a piezoelectric stage, and mechanically amplifying a
resulting displacement of the piezoelectric stage to scan the two-photon output beam over the entire depth range;

sampling a plurality of points within the sample by collecting fluorescence resulting from interaction of the output laser
beam and the sample at each of the points; and

detecting the biomarker from the fluorescence collected from each the plurality of points.

US Pat. No. 9,482,861

OPTICAL DEVICES WITH SWITCHABLE PARTICLES

The Regents Of The Univer...

1. A magnetically switchable optical device comprising:
a display component that defines an optic feature and comprises a housing having a first side, a second opposite side, and
an interior comprising a plurality of anisotropic multiphasic particles, each respective anisotropic multiphasic particle
comprising a first phase and at least one additional phase distinct from the first phase, wherein the first phase comprises
a first colorant so that the anisotropic multiphasic particle has optically distinct phases and at least one of the first
phase or the at least one additional phase comprises a magnetic material receptive to a magnetic field; and

a magnetic field generator comprising a magnet disposed external to the housing, wherein the magnet has a non-pole surface
that is translatable from a first position adjacent to the first side of the housing of the display component for inducing
orientation of the plurality of anisotropic multiphasic particles in a first optical state to a second position adjacent to
the second opposite side for inducing orientation of the plurality of anisotropic multiphasic particles to a second optical
state distinct from the first optical state.

US Pat. No. 9,365,899

FIG4 GENE MUTATIONS IN NEURODEGENERATION

THE REGENTS OF THE UNIVER...

1. A method of detecting a mutation in a FIG4 gene, comprising: a) contacting a FIG4 gene in a biological sample from a human
subject with an oligonucleotide that specifically binds to a mutation in a variant FIG4 nucleic acid under high stringency
conditions but does not bind to a FIG4 nucleic acid not comprising a mutation, wherein the oligonucleotide is labeled with
a reporter molecule; and b) detecting hybridization of the oligonucleotide to the FIG4 gene, wherein detecting hybridization
is indicative of a mutation in a FIG4 gene; wherein said mutation in a variant FIG4 nucleic acid is selected from the group
consisting of: a T>C at a position corresponding to position 293 of SEQ ID NO: 1; a C>T at a position corresponding to position
718 of SEQ ID NO: 1; and a deletion of the sequence ATCAGGCA starting at a position corresponding to position 1214 of SEQ
ID NO:1.

US Pat. No. 9,315,618

COMPOSITIONS FOR DIRECTED ALIGNMENT OF CONJUGATED POLYMERS

The Regents Of The Univer...

1. A conductive polymer comprising an aromatic repeating unit, the repeating unit comprising:
a) an aromatic ?-conjugated backbone comprising three or four aromatic rings, and further comprising at least one sulfur atom
and at least one fluorine atom, the sulfur and fluorine atoms being located on adjacent aromatic rings and separated by three
carbon atoms of the ?-conjugated backbone;

b) an aliphatic ring fused to at least one of the aromatic rings of the repeating unit;
c) two side chains connected to an sp3 carbon of the fused aliphatic ring, wherein the side chains are aliphatic and have 4 or more non-hydrogen atoms.

US Pat. No. 9,370,527

AMELIORATION OF INTESTINAL FIBROSIS AND TREATMENT OF CROHN'S DISEASE

The Regents Of The Univer...

1. A method of treating a subject to relieve the symptoms of inflammatory bowel disease, the method comprising administering
to the subject a therapeutically effective dose of a compound of Formula (I)

wherein Et is ethyl,
wherein the dashed line indicates a single bond between carbon 22 and carbon 23, and
wherein the configuration at carbon 24 to which Et is attached is in the R configuration or the S configuration.

US Pat. No. 9,335,972

TRUE RANDOM NUMBER GENERATOR

The Regents of the Univer...

1. An apparatus for generating a value for deriving a random number comprising:
a ring oscillator;
a control circuit configured to trigger the ring oscillator to start oscillating in a first mode of oscillation at an oscillation
start time; and

a time measuring circuit configured to measure a collapse time value indicative of a length of time from the oscillation start
time to an oscillation collapse time at which the ring oscillator switches from the first mode of oscillation to a second
mode of oscillation.

US Pat. No. 9,234,078

CONJUGATED GOLD NANOPARTICLES

The Regents of the Univer...

1. A method for making conjugated gold nanoparticles comprising:
a) providing:
i) naked gold nanoparticles, wherein each of said naked gold nanoparticles has an gold surface, and wherein at least 90% of
said gold surface is exposed and not attached to any molecules, and

ii) first type of attachment molecules having the formula R1-polymer-R2, wherein R1 is a moiety having affinity for said gold
surface of said naked gold nanoparticles, and wherein R2 is a functional group that allows attachment to other chemicals,
and/or comprises a targeting ligand, and

iii) second type of attachment molecules having the formula R3-polymer-R4, wherein R3 is a moiety having affinity for said
gold surface, and wherein R4 is a functional group that allows attachment to other chemicals, and/or comprises a targeting
ligand, and

wherein either: A) said first type of attachment molecules possess a positive charge and said second type of attachment molecules
possess a negative charge, or B) said first type of attachment molecules posses a negative charge and said second type of
attachment molecules posses a positive charge;

b) mixing said first type of attachment molecules with said naked gold nanoparticles in a first molar ratio of said first
type of attachment molecules to said naked gold nanoparticles such that said first type of attachment molecules attach to
said naked gold nanoparticles at a density level below the saturation level for said naked gold nanoparticles thereby generating
unsaturated conjugated gold nanoparticles; and

c) mixing said second type of attachment molecules with said unsaturated conjugated gold nanoparticles in a second molar ratio
of said second type of attachment molecules to said unsaturated conjugated gold particles such that said second type of attachment
molecules attach to said unsaturated conjugated gold nanoparticles thereby generating double-conjugated gold nanoparticles,
and

wherein said double-conjugated gold nanoparticles posses a ratio of negative to positive attachment molecules of 900/100 to
700/300.

US Pat. No. 9,611,491

BIOSYNTHETIC PATHWAY FOR HETEROLOGOUS EXPRESSION OF A NONRIBOSOMAL PEPTIDE SYNTHETASE DRUG AND ANALOGS

THE REGENTS OF THE UNIVER...

1. A host cell transformed with a polynucleotide encoding (i) the EtuA1 polypeptide (SEQ ID NO: 1) of a nonribosomal peptide
synthetase or a protein 95% identical to SEQ ID NO: 1 having EtuA1 activity, and (ii) the EtuA3 polypeptide (SEQ ID NO: 3)
of a nonribosomal peptide synthetase or a protein 95% identical to SEQ ID NO: 3 having EtuA3 activity.

US Pat. No. 9,403,126

ULTRAFILTRATION MEMBRANE, DEVICE, BIOARTIFICIAL ORGAN, AND RELATED METHODS

THE REGENTS OF THE UNIVER...

1. An ultrafiltration system comprising:
a) a membrane consisting of a plurality of nanofabricated slit shaped pores having a width less than 20 nanometers, wherein
said plurality of nanofabricated slit shaped pores are arranged in a rectangular configuration on said membrane, wherein said
rectangular configuration is at least a 2:1 arrangement of said nanofabricated slit shaped pores on said membrane, wherein
said nanofabricated slit shaped pores are arranged in the center of said membrane, wherein the distance between said nanofabricated
slit shaped pores on said membrane is around 50 nm, wherein the thickness of the membrane is approximately 500 nm, wherein
the membrane has a porosity around 20%;

b) a housing containing said membrane; and
c) a fluid delivery passageway with a first end and a second end, said first end positioned outside of said housing, said
second end positioned to deliver fluid across said membrane.

US Pat. No. 9,504,688

METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION

THE REGENTS OF THE UNIVER...

8. A method of inhibiting the growth or biological activity of S. aureus and/or S. epidermidis, comprising contacting said S. aureus and/or S. epidermidis with a compound having the structure of Formula I, II, III or IV

Wherein X is S, NH, or O, R1 and R2 are, independently, selected from the group consisting of a C1-C8 alkyl, a C1-C8 alkenyl, and a C1-C8 cycloalkyl, wherein
said C1-C8 alkyl, a C1-C8 alkenyl, and a C1-C8 cycloalkyl are optionally substituted with F, CN, OR6, NR62, COR6, CO2R6, CONHR6, aryl or heteroaryl, wherein one or more alkyl carbons may be replaced by O;

R3 and R4 are independently H, a C1-C8 alkyl, or joined in a cycloalkyl ring of 3-7 carbons wherein at least one ring CH2 is replaced by O or N-G;

G is selected from the group consisting of H, C(?O)R6, SO2R6 and C(?O)OR6;

R5 is selected from the group consisting of H, C1-C6 alkyl, CN, OR6, NR62, COR6, CO2R6, CONHR6, aryl, heteroaryl, SO2R6, NHCOR6, SO2NHR6, and OCOR6;

R6 is selected from the group consisting of H, C1-C6 alkyl, C0-C3 alkyl-aryl, and C0-C3 alkyl-heteroaryl, all optionally substituted;

R7 and R8 are independently selected from the group consisting of H, C1-C6 alkyl, and joined in a cycloalkyl ring of 3-7 carbons, wherein
one of the ring CH2 groups may be replaced by O or N-G;

R9 is a C1-C5 alkyl;

R10 is a C2-C8 alkyl or alkenyl or cycloalkyl, optionally substituted with F, CN, OR6, NR62, CO2R6, CONHR6, aryl or heteroaryl, wherein one or more alkyl carbons may be replaced by O; and

R11 is H or a C1 alkyl,

wherein said compound inhibits the growth or biological activity of said S. aureus and/or S. epidermidis.

US Pat. No. 9,288,048

REAL-TIME FRAME AUTHENTICATION USING ID ANONYMIZATION IN AUTOMOTIVE NETWORKS

The Regents Of The Univer...

1. A computer-implemented method for authenticating data frames sent in a vehicle network of a vehicle, comprising:
storing, by a receiving electronic control unit, a cryptographic key, where the cryptographic key is shared with a sending
electronic control unit and the receiving electronic control unit is implemented on a hardware microprocessor;

receiving, by the receiving electronic control unit, a current frame identifier in a data frame sent via a serial data link
by the sending electronic control unit;

generating, by the receiving electronic control unit, a next frame identifier in response to receiving the current frame identifier,
where the next frame identifier is derived in part from the current frame identifier and the cryptographic key using an encoding
function;

storing, by the receiving electronic control unit, the next frame identifier in a data store for subsequent processing;
receiving, by the receiving electronic control unit, another data frame subsequently to receiving the current frame identifier;
extracting, by the receiving electronic control unit, a frame identifier from the another data frame without decoding any
portion of the another data frame;

comparing, by the receiving electronic control unit, the extracted frame identifier to the next frame identifier residing
in the data store;

processing, by the receiving electronic control unit, payload of the another data frame when the extracted frame identifier
matches the next frame identifier; and

discarding, by the receiving electronic control unit, the another data frame when the extracted frame identifier does not
match the next frame identifier, wherein the data frame and the next frame are transmitted according to the priority specified
in their frame identifiers.

US Pat. No. 9,732,067

COMPOUNDS AND METHODS FOR ACTIVATING THE APOPTOTIC ARM OF THE UNFOLDED PROTEIN RESPONSE

University of Kansas, La...

1. A compound having the structure of Formula I, or a pharmaceutically acceptable salt, ester or prodrug thereof,

wherein
X is C;
R1 is a hydrogen; and

R2 is a substituted alkyl group.

US Pat. No. 9,650,656

BIOSYNTHETIC SYSTEMS PRODUCING FUNGAL INDOLE ALKALOIDS

THE REGENTS OF THE UNIVER...

1. A protein in the prenylated indole alkaloid pathway, wherein the protein is a MalG protein having an amino acid sequence
that is 98% or more identical to SEQ. ID NO: 15, comprises at least one amino acid substitution, insertion or deletion relative
to SEQ ID NO: 15 and has MalG activity.
US Pat. No. 9,353,178

STEM CELL FACTOR INHIBITOR

THE REGENTS OF THE UNIVER...

1. An anti-stem cell factor antibody that specifically binds to stem cell factor isoform b relative to stem cell factor isoform
a or an antigen-binding antibody fragment that specifically binds to stem cell factor isoform b relative to stem cell factor
isoform a.

US Pat. No. 9,118,113

PHASED ANTENNA ARRAYS USING A SINGLE PHASE SHIFTER

THE REGENTS OF THE UNIVER...

1. A phased array comprising:
a plurality of antennas;
a feed network comprising a plurality of coupling stages each coupled to a respective one of the plurality of antennas for
coupling a respective portion of a first traveling signal to the respective antenna, the first traveling signal traveling
in a first direction relative to the plurality of antennas and resulting from an input signal to the feed network; and

a tunable phase shifting stage configured to receive the first traveling signal and produce a phase shifted second traveling
signal, wherein the tunable phase shifting stage is configured to tunably adjust the phase of the second traveling signal
resulting from the first traveling signal to scan a beam produced by the phased array, wherein the second traveling signal
travels in the feed network in a second direction relative to the plurality of antennas, the second direction being opposite
the first direction of the first travelling signal, such that each coupling stage couples a respective portion of the second
traveling signal and the respective portion of the first traveling signal to the respective antenna for that coupling stage.

US Pat. No. 9,057,054

ANTIGEN-SPECIFIC LONG-TERM MEMORY T-CELLS

THE REGENTS OF THE UNIVER...

1. A method of generating a population of antigen-specific memory T-cells comprising:
a) processing an initial sample from a subject under conditions such that an isolated T-cell sample is generated,
wherein said initial sample is selected from: a peripheral blood sample, a spleen sample, and a lymph node sample, and
wherein said isolated T-cell sample comprises purified cells, wherein substantially all of said purified cells present in
said T-cell sample are unprimed CD44? CD8+ T-cells as a result of said processing; and

b) contacting said isolated T-cell sample, which contains said unprimed CD44? CD8? T-cells, with: i) an antigen, ii) antigen presenting cells, and iii) an mTOR pathway inhibiting agent, under conditions such
that a memory T-cell sample is generated that comprises memory T-cells specific to said antigen, wherein substantially all
of said memory T-cells present in said memory T-cell sample are CD44? CD62L+ CD8+;

wherein said mTOR pathway inhibiting agent is selected from the group consisting of: rapamycin, temsirolimus, everolimus torin,
and deforolimus.

US Pat. No. 9,157,551

RECONFIGURABLE MICROACTUATOR AND METHOD OF CONFIGURING SAME

The Regents of the Univer...

1. A reconfigurable latchable microactuator system comprising:
a substrate assembly having opposing outer surfaces and including a substrate, a plurality of actuation cells having opposing
end surfaces and being embedded in the substrate, and a membrane defining one of the outer surfaces and being arranged to
cover one of the end surfaces of each of the actuation cells, each of the actuation cells being configured to melt if heated
by a source of electromagnetic radiation; and

a helmet chip operatively arranged with the substrate assembly, including the membrane, to form a common pressure chamber
adjacent to the actuation cells, each of the actuation cells being further configured to deform when melted if subjected to
pressure via the pressure chamber.

US Pat. No. 9,061,131

DISPOSABLE ACOUSTIC COUPLING MEDIUM CONTAINER

HISTOSONICS, INC., Ann A...

1. An ultrasound therapy device, comprising:
a frame configured to conform to and provide a liquid seal against a patient's skin, the frame defining an open aperture;
a rectal imaging probe configured to image a patient's prostate;
a reservoir portion configured to hold an acoustic coupling medium, the reservoir portion being configured to provide the
acoustic coupling medium in direct contact with the patient's skin through the open aperture, the reservoir portion further
comprising a sheath configured to receive the rectal imaging probe; and

an ultrasound transducer coupled to the frame and in acoustic communication with the acoustic coupling medium, wherein movement
of the ultrasound transducer relative to the frame maintains acoustic communication between the ultrasound transducer and
the acoustic coupling medium.

US Pat. No. 9,385,692

LOW POWER OSCILLATOR WITH CHARGE SUBTRACTION SCHEME

The Regents Of The Univer...

1. A low power oscillator, comprising:
an integrating capacitor;
a current source configured to charge the integrating capacitor;
a subtraction circuit electrically coupled to the integrating capacitor and operable to subtract a fixed amount of charge
from the integrating capacitor in response to a trigger signal, wherein the current source continues to charge the integrating
capacitor while the subtraction circuit subtracts the fixed amount of charge from the integrating capacitor; and

a first comparator configured to receive voltage across the integrating capacitor and compare the capacitor voltage to a first
reference voltage, wherein the first comparator provides a trigger signal to the subtraction circuit when the integrating
capacitor voltage exceeds the first reference voltage.

US Pat. No. 9,120,744

PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM

THE REGENTS OF THE UNIVER...

1. A compound of formula CLVII or a salt, ester, or prodrug thereof:

wherein
k, l, and o are independently 0, 1, 2, 3, 4, 5, or 6;
W is C or N;
X1, X2, X3, X4, and X5 are independently selected from the group consisting of —H, —OH, —OR, —F, —Cl, —Br, —I, —NO2, —NO, —N(R)2, —N(R)3+, —C(O)R,—C(O)OR, —CHO, —C(O)NH2, —C(O)SR, —CN, —S(O)2R, —SO3R, —SO3H, —SO2N(R)2, —S?O, aryl, substituted aryl, heteroaryl, and substituted heteroaryl;

Y1 is selected from the group consisting of O, NH, NRa, S, and CH2;

Y2 is selected from the group consisting of O, NH, NRb, S, and CH2;

R, Ra, and Rb are independently selected from the group consisting of C1 to C6 alkyl, C3 to C6 cycloalkyl, CH2—C3-C6 cycloalkyl, phenyl, tolyl, and benzyl;

Z1 and Z2 are independently selected from the group consisting of C, P—OH, S, and S?O;

U is selected from the group consisting of —NRcC(O)ORe, —NRcC(O)NRfRe, —NRcC(O)SRe, —NRcP(O)(OH)Re, —NRcP(O)(OH)ORe, —NRcP(O)(OH)NRfRe, —NRcP(O)(OH)SRe, —NRcS(O)Re, —NRcS(O)ORe, —NRcS(O)NRfRe, NRcS(O)SRe, —NRcS(O)2Re, —NRcS(O)2ORe, NRcS(O)2NRfRe, —NRcS(O)2SRe, —OC(O)ORe, —OC(O)NRfRe, —OC(O)SRe, —OP(O)(OH)Re, —OP(O)(OH)ORe, —OP(O)(OH)NRdRe, —OP(O)(OH)SRe, —OS(O)Re, —OS(O)ORe, —OS(O)NRdRe, —OS(O)SRe, —OS(O)2Re, —OS(O)2ORe, —OS(O)2NRdRe, —OS(O)2SR, and —C(O)Rc;

Rc and Rd are independently selected from the group consisting of H, C1 to C12 alkyl, C1 to C12 haloalkyl, C3 to C6 cycloalkyl, (CH2)m—C3-C6 cycloalkyl, C2 to C6 heterocycloalkyl, (CH2)m—C2-C6 heterocycloalkyl, benzyl, aryl, (CH2)m-aryl, heteroaryl, (CH2)m-heteroaryl, and substituted derivatives thereof, or Rc and Rd taken together with the N atom to which they are bonded form a 3- to 8-membered heterocyclic ring;

m is 1, 2, 3, 4, 5, or 6;
Rf is selected from the group consisting of H, C1 to C12 alkyl, C1 to C12 haloalkyl, C3 to C6 cycloalkyl, (CH2)m—C3-C6 cycloalkyl, C2 to C6 heterocycloalkyl, (CH2)m—C2-C6 heterocycloalkyl, benzyl, aryl, (CH2)m-aryl, heteroaryl, (CH2)m-heteroaryl, and substituted derivatives thereof; and

Re is selected from the group consisting of H, C1 to C12 alkyl, C1 to C12 haloalkyl, C3 to C6 cycloalkyl, (CH2)m—C3-C6 cycloalkyl, C2 to C6 heterocycloalkyl, (CH2)m—C2-C6 heterocycloalkyl, benzyl, aryl, (CH2)m-aryl, heteroaryl, (CH2)m-heteroaryl,


 and substituted derivatives thereof.

US Pat. No. 9,352,146

PERIPHERAL NERVE INTERFACE DEVICES FOR TREATMENT AND PREVENTION OF NEUROMAS

The Regents Of The Univer...

1. An implantable nerve interface cap device to treat, minimize, or prevent neuroma formation in a nerve of a subject, the
device comprising:
a housing comprising a scaffold material, the housing defining an enclosed cylindrical capped structure having a single opening
capable of receiving a nerve ending therein; and

an interior region within the housing for receiving an autograft of muscle tissue or dermis tissue from the subject, wherein
the interior region facilitates contact of the autograft with a portion of the nerve ending after implantation, so that the
nerve ending grows within and innervates the autograft in the interior region of the housing to treat, minimize, or prevent
neuroma formation.

US Pat. No. 9,187,594

NANO-FIBROUS MICROSPHERES AND METHODS FOR MAKING THE SAME

The Regents of The Univer...

1. A nano-fibrous microsphere, comprising:
a plurality of nano-fibers aggregated together in a spherical shape to form a shell of the microsphere, the nano-fibers formed
of a star-shaped polymer including:

a multi-functional molecule having at least three branches; and
an oligomer or a polymer chain initiated from or coupled to the at least three branches of the multi-functional molecule;
a plurality of pores formed between at least some of the plurality of nano-fibers;
one hollow core formed in a center of the microsphere, the one hollow core being surrounded by the plurality of nano-fibers;
and

a dispersing medium present in the one hollow core wherein the diameter of the microsphere ranges from about 10 ?m to about
180 ?m.

US Pat. No. 9,103,727

COMPOSITE FABRY-PéROT SENSOR

The Regents of The Univer...

1. An optical sensor device, comprising:
a substrate;
a first cavity portion disposed within the substrate and having a first depth;
a second cavity portion disposed within the substrate and having a second depth; and
a dielectric material disposed within the first and second cavity portions,
wherein the first cavity portion is juxtaposed to the second cavity portion and the first depth is offset by a predetermined
distance from the second depth.

US Pat. No. 9,274,045

OPTICALLY-INDUCED CHARGE SEPARATION AND INDUCED MAGNETISM IN DIELECTRICS FOR OPTICAL ENERGY CONVERSION AND INTENSE MAGNETIC FIELD GENERATION

THE REGENTS OF THE UNIVER...

1. An optically-pumped AC current or voltage source comprising:
a non-conducting transparent substrate;
a laser source coupled to supply a laser output into the substrate, the laser output having an intensity above a threshold
for inducing saturated dipole magnetization in the substrate;

a switch for switching the direction of propagation of the laser output supplied to the substrate between a forward direction
and a backward direction propagating through the substrate, at a rate ?; and

a circuit coupled across the substrate to receive and convert an electrical AC charge oscillation, generated by the laser
output supplied to the substrate, into a DC current for supplying a load.

US Pat. No. 9,249,506

COMPACT ORGANIC VAPOR JET PRINTING PRINT HEAD

The Regents of the Univer...

1. A device, comprising:
a print head;
a manifold;
at least one feed through tube located on a side of the manifold opposite the print head; and
a first gas source located between the manifold and the print head and hermetically sealed to the print head,
the print head further comprising:
a first layer further comprising a plurality of nozzles, each nozzle having an aperture, and each aperture having a smallest
dimension of 0.5 to 500 microns; and

a second layer bonded to the first layer, the second layer further comprising a first via in fluid communication with the
first gas source and at least one of the nozzles, wherein the second layer is made of an insulating material, and

wherein at least one of the first layer and the second layer is configured to be heated by a heat source associated with the
print head,

wherein the heat source is incorporated into the at least first layer or the second layer of the print head, and
wherein the heat source is a resistive element embedded in the at least first layer or the second layer of the print head.
US Pat. No. 9,193,952

METHODS FOR REGULATING NEURAL DIFFERENTIATION

The Regents of the Univer...

1. An in vitro method of producing a population of predominantly astrocytes comprising:
overexpressing miRNA-410 in a population of neural stem cells or neuronal or glial precursor cells and,
culturing said cells,
wherein said overexpressing miRNA-410 and said culturing results in differentiation of said cells into a population of predominantly
astrocytes,

thereby producing a population of predominantly astrocytes.

US Pat. No. 9,444,515

SHORT-RANGE ZIGBEE COMPATIBLE RECEIVER WITH NEAR-THRESHOLD DIGITAL BASEBAND

The Regents Of The Univer...

1. A method for operating a short-range receiver with a digital baseband processor, comprising:
receiving, by a RF front-end circuit in the receiver, a network data packet over a data link of a wireless network;
sampling, by an analog-to-digital converter, a portion of the network data packet at a given sampling rate;
determining, by the digital baseband processor, a metric indicative of quality of the data link over which the network data
packet was received;

lowering, by the digital baseband processor, the given sampling rate of the network data packet to a reduced uniform or non-uniform
sampling rate, where the reduced sampling rate is set inversely to quality of the data link and has a value lower than the
given sampling rate; and

processing, by the digital baseband processor, remainder of the network data packet at the reduced sampling rate, wherein
lowering the given sampling rate further comprises disabling the analog-to-digital converter for a portion of the sampling
interval and disabling at least one other active circuit in the receiver for the portion of the sampling interval.

US Pat. No. 9,362,015

SILICON-BASED SOLAR CELL WITH EUTECTIC COMPOSITION

The Regents Of The Univer...

1. A material for a photovoltaic cell comprising a eutectic or near-eutectic composition having a first phase comprising silicon
(Si) and a second phase comprising a metal silicide, wherein the first phase and the second phase respectively comprise orthogonal
domains that together define a lamellar architecture in the material and form a lamellar heterojunction between the first
phase and the second phase.

US Pat. No. 9,498,566

SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF

CYTOPHERX, INC., Ann Arb...

1. A system for treating activated platelets from a subject in need thereof, the system comprising:
a device comprising a housing defining a passageway that permits body fluid from the subject to pass therethrough and a fiber
or a plurality of fibers disposed within the housing, wherein each fiber has an exterior surface that binds the platelets;
and

a calcium chelating agent comprising citrate present in an amount sufficient to inhibit the release of a pro-inflammatory
substance from the activated platelets or to deactivate the platelets.

US Pat. No. 9,486,422

SMALL MOLECULE INHIBITORS OF MCL-1 AND THE USES OF THEREOF

THE REGENTS OF THE UNIVER...

1. A compound having the following formula;
and
wherein X is selected from the group consisting of

wherein R2 is selected from the group consisting of —H, CH3,


US Pat. No. 9,260,863

DYNAMICALLY RESPONSIVE ACOUSTIC TUNING ENVELOPE SYSTEM AND METHOD

THE REGENTS OF THE UNIVER...

1. A system comprising:
an acoustic shell comprising a plurality of panels arranged in a tessellated pattern relative to one another, the plurality
of panels including at least one sound reflecting panel and at least one sound absorbing panel, the at least one sound reflecting
panel having an exposed surface a majority of which comprises a sound reflecting surface, the at least one sound absorbing
panel having an exposed surface a majority of which comprises a sound absorbing surface;

a plurality of hinges connecting edges of at least three of the panels to edges of immediately adjacent panels such that each
panel is movably connected to at least one other immediately adjacent panel;

a plurality of surficial actuators, each surficial actuator connected between at least two of the plurality of panels for
moving the two panels relative to each other such that the plurality of surficial actuators can manipulate the plurality of
panels to change the overall sound reflecting and sound absorbing properties of the acoustic shell; and

a controller for at least controlling the surficial actuators.

US Pat. No. 9,174,990

2-AMINO-9-[(2-HYDROXYMETHYL) CYCLOPROPYLIDENEMETHYL] PURINES AS ANTIVIRAL AGENTS

WAYNE STATE UNIVERSITY, ...

1. A method of treating a mammal infected with a virus selected from the group consisting of a cytomegalovirus (CMV), herpes
simplex virus-1 (HSV-1), herpes simplex virus-2 (HSV-2), human herpes virus-6 (HHV-6), human herpes virus-7 (HHV-7), human
herpes virus-8 (HHV-8), and hepatitis B virus (HBV) comprising the step of administering to said mammal an effective amount
of:
a compound having Formula 1 or Formula 2:

wherein B is 2-aminopurine-9-yl, unsubstituted or substituted at the 6 position with NHR1, OR2, or SR3;

R1 is selected from the group consisting of alkenyl, alkynyl, and benzyl, any of which may be optionally substituted with one
or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl;

R2 is selected from the group consisting of alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and
optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl,
and aryl; and

R3 is selected from the group consisting of alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched
and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl
and aryl;

or
a compound having Formula 3 or Formula 4:

wherein X is O;
R1 and R2 are alkyl or aryl; or R1X or R2X is an amino acid residue with X as NH;

B is 2-aminopurine-9-yl, which is unsubstituted or substituted at the 6 position with NHR4, OR5, or SR6;

R4 is selected from the group consisting of alkenyl, and alkynyl, any of which may be optionally substituted with one or more
members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl;

R5 is selected from the group consisting of alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and
optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl
and aryl;

R6 is selected from the group consisting of alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched
and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl
and aryl;

or a combination thereof.
US Pat. No. 9,151,713

SENSITIVE INTRACAVITY BIOSENSING PLATFORM AND METHODS FOR DETECTION THEREWITH

The Regents Of The Univer...

1. A method of detecting a target analyte, the method comprising:
binding the target analyte and a probe comprising at least one fluorophore to form a fluid composition;
exciting the fluid composition within a laser cavity; and
measuring a laser emission from the fluid composition based on an interaction between the target analyte and the probe.

US Pat. No. 9,140,717

APPARATUS AND METHOD FOR IDENTIFYING AND ANALYZING THE FREE FLIGHT DYNAMICS OF A BODY

The Regents of The Univer...

1. An apparatus for analyzing free flight of a body of sports equipment, said apparatus comprising:
an inertial measurement unit having no more than one accelerometer continuously measuring no more than three acceleration
signals representing no more than three orthogonal axes of acceleration and outputting data representative thereof; and

a processing unit operably receiving said data, said processing unit algebraically computing three components of an angular
velocity of the body of sports equipment from said data representative of said measured three orthogonal axes of acceleration.

US Pat. No. 9,120,820

FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS

CAYMAN CHEMICAL COMPANY, ...

1. A fluorescent detection analyte having the structure of Formula (II):

wherein any two of R2, R2?, and R3?R3? are hydrogen and the third is a linker component having a linker moiety bonded to a fluorophore moiety.

US Pat. No. 9,275,702

MEMORY CIRCUITRY INCLUDING READ VOLTAGE BOOST

The Regents of the Univer...

1. Memory circuitry comprising:
an array of bit cells comprising a plurality of columns of bit cells;
a plurality of bit lines coupled to said plurality of columns of bit cells within said array;
sense amplifier circuitry configured to sense a voltage change on at least one of said plurality of bit lines during a read
operation;

at least one boost capacitor; and
boost control circuitry configured to couple said at least one boost capacitor to said at least one of said plurality of bit
lines in one of a plurality of configurations including:

(i) a sampling configuration in which said at least one boost capacitor is coupled to said at least one of said plurality
of bit lines with a first polarity and an initial voltage change upon said at least one of said plurality of bit lines during
said read operation produces a sampled charge with a sampled voltage difference to be stored by said at least one boost capacitor;
and

(ii) a boost configuration in which said at least one boost capacitor is coupled to said at least one of said plurality of
bit lines with a second polarity, said second polarity is a reverse of said first polarity, and said sampled voltage difference
is added to said voltage change on said at least one of said plurality of bit lines and supplied to said sense amplifier circuitry.

US Pat. No. 9,241,634

ANALYTIC MORPHOMICS: HIGH SPEED MEDICAL IMAGE AUTOMATED ANALYSIS METHOD

The Regents Of The Univer...

13. A computer-implemented method for anatomically indexing a subject, comprising:
receiving input image data representing a volume of a subject, the input image data including at least a portion of a vertebral
column of the subject;

identifying the vertebral column of the subject in the input image data;
determining one or more markers for the vertebral column, where each of the markers is indicative of the location of vertebral
column and the location is defined as coordinates in coordinate system associated with the image data;

defining a vertebral coordinate system using the markers, where the coordinates for one or more markers define at least one
origin of the vertebral coordinate system and the vertebral coordinate system differs from the coordinate system associated
with the image data;

locating another anatomical component in the subject using at least one of the markers for the vertebral column, the anatomical
component differs from the vertebral column and being selected from the group comprised of an organ, a muscle and a bone;

determining a measure for the anatomical component;
determining location of the anatomical component in relation to the vertebral coordinate system; and
storing the measure for the anatomical component, along with the location of the anatomical component, in a database.

US Pat. No. 9,808,616

REGENERATIVE PERIPHERAL NERVE INTERFACE

THE REGENTS OF THE UNIVER...

1. A regenerative peripheral nerve interface (RPNI) for a subject comprising:
an insulating substrate and at least one metallic electrode disposed on or in the insulating substrate, so that the insulating
substrate and the at least one metallic electrode define a thin-film array;

a layer of decellularized biotic material comprising decellularized small intestinal submucosa (SIS); and
at least one conductive polymer.

US Pat. No. 9,403,322

SYSTEMS AND METHODS FOR FABRICATING THREE-DIMENSIONAL OBJECTS

GEORGIA TECH RESEARCH COR...

1. A method for creating a three-dimensional model comprising:
moving a maskless optical imaging system in a continuous sequence with one micron positioning accuracy proximate a photosensitive
medium;

exposing a predetermined portion of the photosensitive medium to an energy source from the maskless optical imaging system;
lowering a plate upon which the photosensitive medium resides with one micron positioning accuracy; and
applying a new layer of photosensitive medium.

US Pat. No. 9,159,416

SILICON BASED NANOSCALE CROSSBAR MEMORY

The Regents of The Univer...

1. A method for a crossbar memory array having a first plurality of metallic nanowires, a second plurality of metallic nanowires,
and a plurality of resistive memory devices electrically disposed between the first plurality of metallic nanowires and the
second plurality of metallic nanowires, the method comprising:
applying with a control circuit a voltage to a gate of a first transistor;
coupling a source of the first transistor to a drain of the first transistor in response to the voltage applied to the gate
to thereby cause a first voltage to be applied across a first metallic nanowire from the first plurality of metallic nanowires,
a second metallic nanowire from the second plurality of metallic nanowires, and a resistive memory device from the plurality
of resistive memory devices, wherein the resistive memory device comprises a layer of resistive switching material contacting
the first metallic nanowire, and a layer of conductive silicon bearing material having a first surface contacting the layer
of resistive switching material and having a second surface contacting the second metallic nanowire;

supplying a plurality of metallic particles from the first metallic nanowire to the layer of resistive switching material
in response to the first voltage being applied, wherein metallic particles from the plurality of metallic particles are supplied
to a plurality of defect sites within the layer of resistive switching material in response to the first voltage;

removing with the control circuit the voltage from the gate of the first transistor;
decoupling the source of the first transistor to the drain of the first transistor in response to the first voltage being
removed from the gate to thereby cause the first voltage to be removed from across the first metallic nanowire, the second
metallic nanowire, and the resistive memory device;

wherein the plurality of metallic particles become trapped in the plurality of defect sites within the layer of resistive
switching material in response to the first voltage being removed;

wherein the plurality of metallic particles form a conductive filament within the layer of resistive switching material; and
wherein a first resistance of the resistive memory device is characterized by a first tunneling resistance between the layer
of conductive silicon bearing material and the conductive filament.

US Pat. No. 9,075,675

RANDOMIZED VALUE GENERATION

The Regents of the Univer...

1. The data processing apparatus comprising:
a cell comprising a dielectric oxide layer;
stress voltage circuitry configured to apply a stress voltage across said dielectric oxide layer of said cell to cause an
oxide breakdown process to occur;

oxide breakdown detection circuitry configured to determine a current extent of said oxide breakdown process by measuring
a response of said dielectric oxide layer to said stress voltage; and

randomized value determination circuitry configured to determine a randomized value in dependence on said current extent of
said oxide breakdown process, wherein said randomized value determination circuitry is configured to determine said randomized
value in dependence on a time period measurement of a time period between application of said stress voltage and determination
by said oxide breakdown detection circuitry of occurrence of an oxide breakdown event, said oxide breakdown event corresponding
to a predetermined extent of said oxide breakdown process.

US Pat. No. 9,053,534

VOXEL-BASED APPROACH FOR DISEASE DETECTION AND EVOLUTION

THE REGENTS OF THE UNIVER...

1. A computer-implemented method of analyzing a sample region of a body to predict the evolution of a disease, the method
comprising:
collecting, using a magnetic resonance imaging (MRI) medical imaging device, a weighted reference image data set of a brain
tumor taken at a first time point, the weighted reference image data set comprising a first plurality of voxels each characterized
by a signal value in the reference image data set;

collecting, using the MRI medical imaging device, a weighted second image data set of the brain tumor taken at a time after
the first time point, the weighted second image data set comprising a second plurality of voxels each characterized by a signal
value in the second image data set;

normalizing the weighted reference image data set to a tissue or a structure in the brain tumor taken at the first time point,
and normalizing the weighted second image data set to a tissue or a structure in the brain tumor taken at a time after the
first time point;

registering via computer-executable instructions, the normalized reference image data set and the normalized second image
data set to produce a co-registered image data set that comprises a plurality of co-registered voxels, wherein each of the
co-registered voxels includes the signal value of the co-registered voxel of the reference image data set and the second image
data set, and wherein each of the co-registered voxels includes the value of the difference between the co-registered voxel
of the reference image data set and the second image data set;

determining a threshold significance level for the value of the difference between the co-registered voxel of the reference
image data set and the second image data set;

quantifying the volume of voxels that exceed the threshold significance level;
forming a parametric response map via computer-executable instructions using the co-registered image data set and the threshold
significance level for the value of the difference between the co-registered voxels to segment the parametric response map
data into at least a region that exceeds the threshold significance level; and

establishing a disease growth rate percentage, whereby if the quantity of the co-registered voxels that exceed the threshold
significance level is greater than the established disease growth rate percentage, the tumor is determined to be recurring,
wherein the disease growth rate percentage is a percentage of the whole volume tumor.

US Pat. No. 9,862,312

UNIVERSAL MOTION SICKNESS COUNTERMEASURE SYSTEM

THE REGENTS OF THE UNIVER...

1. A motion sickness countermeasure system for a user within a vehicle, the motion sickness countermeasure system comprising:
a light array system configured to output visual stimuli presented only in a peripheral field of view of the user; and
a controller outputting a control signal to the light array system configured to activate the light array system in such a
way as to mimic the visual input one would receive if one were to look outside the vehicle.

US Pat. No. 9,508,957

OLED WITH IMPROVED LIGHT OUTCOUPLING

The Regents of the Univer...

1. An organic light-emitting device comprising:
a substrate;
a first electrode disposed over the substrate;
an organic layer disposed over the first electrode, the organic layer comprising:
a first region comprising an organic emissive material; and
a second region comprising a transparent low-index material embedded within the organic layer in the form of a grid oriented
in a plane parallel to the first electrode, wherein the grid has a periodic pattern with a periodicity of 5-20 ?m, wherein
the low-index material has a refractive index less than the refractive index of the organic emissive material; and

a second electrode disposed over the organic layer;
wherein at least one of the first and second electrodes is a transparent electrode;
wherein the device emits white light;
wherein the thickness of the transparent low-index material extends from a surface of the first electrode to a surface of
the second electrode; and,

wherein the low-index material has a refractive index less than the refractive index of the substrate.

US Pat. No. 9,419,213

DIRECTLY HEATED RF PHASE CHANGE SWITCH

The Regents Of The Univer...

1. An RF switch having two ports, comprising:
a substrate;
a bottom heater electrode disposed onto a surface of the substrate;
a phase change material disposed onto the bottom heater electrode;
an input electrode and an output electrode disposed on opposing sides of the phase change material and operable to form a
conductive path for an RF signal through the phase change material; and

a top heater electrode disposed onto the phase change material, wherein the top and bottom heater electrodes are configured
to draw a current through the phase change material in a direction transverse to the conductive path.

US Pat. No. 9,367,461

ORDERING CONSTRAINT MANAGEMENT WITHIN COHERENT MEMORY SYSTEMS

The Regents of the Univer...

1. Apparatus for processing data comprising:
a plurality of memory access request sources configured to generate memory access requests and each having a cache memory
configured to store one or more blocks of data values corresponding to respective blocks of memory addresses within a memory
address space of a main memory;

a coherency controller configured to receive from a store requester, that is one of said plurality of memory access request
sources, a store request seeking:

(i) to retrieve from said main memory to a cache memory of said store requester a target block of data from a target block
of memory addresses within said memory address space, and

(ii) to store one or more new data values within said target block of data retrieved to said cache memory of said store requester,
and

to provide to said store requester an exclusive right to access data values of said target block of data, wherein:
said coherency controller is configured to provide of said exclusive right to said store requester before said target block
of data is retrieved from said main memory to said cache memory of said store requester; and

said store requester is enabled by said exclusive right to perform a further processing operation having an ordering constraint
specifying that said further processing operation follows said storing of said one or more data values to said target block
of data without waiting for said one or more data values to be stored to said target block of data.

US Pat. No. 9,223,064

PHOTONIC CRYSTAL-METALLIC STRUCTURES AND APPLICATIONS

The Regents Of The Univer...

1. A photonic crystal-metallic structure that receives an input light signal from a light source comprising: a metal structure;
a defect member; and a photonic crystal structure disposed adjacent the metal structure such that the defect member is disposed
between the metal structure and the photonic crystal structure, the photonic crystal structure configured to receive the input
light signal such that the input light signal excites surface plasmons of the metal structure and such that the input light
signal is internally reflected within the photonic crystal structure at a total internal reflection (TIR) boundary defined
at an interface between the defect member and the metal structure.

US Pat. No. 9,211,096

REAL TIME CLINICAL DECISION SUPPORT SYSTEM HAVING MEDICAL SYSTEMS AS DISPLAY ELEMENTS

The Regents Of The Univer...

1. A clinical decision support system for patient treatment comprising:
a monitoring system operably coupled to a patient, said monitoring system passively engaging with the patient, said monitoring
system outputting a first physiological monitoring signal in response to a measured parameter of the patient, said monitoring
system further operably coupled to a medical system associated with the patient, said medical system actively engaging with
the patient to effect a physiological response in the patient, said monitoring system outputting a second physiological monitoring
signal in response to a detected condition of the medical system;

a controller receiving said first and second physiological monitoring signals and continuously calculating a secondary, non-measurable
parameter of the patient based on said measured parameter, said controller performing an automated calculation and outputting
a display signal in response to said automated calculation for use in patient treatment decision-making, said automated calculation
being determined by said controller based on at least said first physiological monitoring signal, said secondary, non-measurable
parameter, data derived from the patient's previously-recorded demographic data, and health data impacting an interpretation
of said first and second physiological monitoring signals derived from an electronic source other than said first physiological
monitoring signal and said medical system; and

a display device operably coupled to said controller and receiving said display signal, said display device having a plurality
of display indicia where at least one of the plurality of display indicia is responsive to said display signal, wherein at
least one of said plurality of display indicia being substantially shaped as a readily-identifiable organ and operable to
actively display a condition indicative of an associated organ of the patient.

US Pat. No. 9,197,188

WIDE RANGE CONTINUOUSLY TUNABLE CAPACITOR BANK

The Regents of The Univer...

6. An electrical circuit, comprising:
one or more resonator circuits, wherein each of the one or more resonator circuits comprises:
a continuously tunable capacitor bank, the capacitor bank comprising
a variable capacitor, the capacitance value of which is adjustable within a predetermined capacitance range defined by a minimum
capacitance value and a maximum capacitance value, and

one or more switched capacitors electrically connected to the variable capacitor,
wherein each of the one or more switched capacitors has a first capacitance value corresponding to an un-actuated state and
a second capacitance value corresponding to an actuated state, and further wherein the second capacitance value is greater
than the first capacitance value and less than or equal to the maximum capacitance value of the variable capacitor, and

further wherein the variable capacitor is configured to allow the capacitance value thereof to be adjusted within the predetermined
capacitance range and the one or more switched capacitors are configured to be selectively actuated to permit continuous tuning
of the capacitor bank over a second capacitance range that is greater than the predetermined capacitance range; and

at least one inductive element electrically connected to the continuously tunable capacitor bank.

US Pat. No. 9,118,026

ORGANIC SEMICONDUCTORS AS WINDOW LAYERS FOR INORGANIC SOLAR CELLS

The Regents of the Univer...

1. A device comprising:
an anode;
a cathode;
an inorganic substrate positioned between the anode and the cathode; and
at least one organic window layer positioned between:
said anode and said inorganic substrate; or
said cathode and said inorganic substrate,wherein the at least one organic window layer has a thickness that is no greater than 25 nm, andwherein the device exhibits an enhanced Schottky barrier height when compared to the device without the at least one organic
window layer.

US Pat. No. 9,801,842

NANOEMULSION THERAPEUTIC COMPOSITIONS AND METHODS OF USING THE SAME

THE REGENTS OF THE UNIVER...

1. A composition consisting of:
a) a nanoemulsion, or a dilution thereof, consisting essentially of:
1) a poloxamer surfactant or polysorbate surfactant;
2) an organic solvent;
3) a halogen containing compound;
4) oil, and
5) water;
b) a chelating agent; and
c) a hypertonic salt solution.
US Pat. No. 9,695,227

BINDING DOMAINS DIRECTED AGAINST GPCR:G PROTEIN COMPLEXES AND USES DERIVED THEREOF

Vrije Universiteit Brusse...

1. A nanobody comprising:
four framework regions (FR1 to FR4) and three complementary determining regions (CDR1 to CDR3), according to Formula (I)
FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4  (I)
wherein the nanobody specifically binds to a complex comprising a GPCR and a G protein;
wherein the nanobody specifically binds to the G protein and not to the GPCR; and
wherein
CDR1 is SEQ ID NO: 13, CDR2 is SEQ ID NO: 25, and CDR3 is SEQ ID NO: 37; or
CDR1 is SEQ ID NO: 14, CDR2 is SEQ ID NO: 26, and CDR3 is SEQ ID NO: 38; or
CDR1 is SEQ ID NO: 15, CDR2 is SEQ ID NO: 27, and CDR3 is SEQ ID NO: 39; or
CDR1 is SEQ ID NO: 16, CDR2 is SEQ ID NO: 28, and CDR3 is SEQ ID NO: 40; or
CDR1 is SEQ ID NO: 17, CDR2 is SEQ ID NO: 29, and CDR3 is SEQ ID NO: 41; or
CDR1 is SEQ ID NO: 18, CDR2 is SEQ ID NO: 30, and CDR3 is SEQ ID NO: 42.

US Pat. No. 9,461,193

FOCUSING LUMINESCENT AND THERMAL RADIATION CONCENTRATORS

The Regents of the Univer...

1. A focusing luminescent concentrator (FLSC) for focusing energy, said FLSC comprising a microcavity comprising:
a top semi-transparent mirror;
a bottom semi-transparent mirror; and
a photosensitive material between the top and bottom semi-transparent mirrors; wherein the photosensitive material re-emits
absorbed energy in a directional manner from the microcavity through the bottom semi-transparent mirror.

US Pat. No. 9,328,421

ORGANIC VAPOR JET PRINTING SYSTEM

The Regents of the Univer...

1. An organic vapor jet printing system, comprising:
a heated chamber configured to produce an organic flux, the flux including a carrier gas and a vapor of an organic material;
a source cell configured to introduce the vapor and the carrier gas into the heated chamber;
a nozzle body configured to direct the flux to a substrate;
a transport line disposed between the heated chamber and the nozzle body, the transport line configured to convey the flux
from the heated chamber to the nozzle body; and

a pump capable of generating pressure pulses in the flux, said pump located within the heated chamber and connected to the
transport line between the source cell and the nozzle body, the pump configured to pump the flux from the chamber to the transport
line and to the nozzle body,

wherein said pump is capable of increasing a pressure of the organic flux before the organic flux exits the nozzle body.

US Pat. No. 9,229,452

DETECTION OF AND COUNTER-MEASURES FOR JACKKNIFE ENABLING CONDITIONS DURING TRAILER BACKUP ASSIST

Ford Global Technologies,...

9. A trailer backup control system for a vehicle towing a trailer, comprising:
an input apparatus for providing a trailer path curvature signal approximating a desired curvature for a reverse path of travel
of the trailer relative to a zero curvature position for backward movement of the trailer in a straight path defined by a
centerline longitudinal axis of the trailer;

a trailer angle sensor for sensing a hitch angle between the vehicle and the trailer; and
a trailer backup assist controller determining vehicle steering information based on the trailer path curvature signal and
the hitch angle and the trailer backup assist controller altering a vehicle operating parameter when a jackknife condition
is imminent.

US Pat. No. 9,111,613

ADAPTIVE READING OF A RESISTIVE MEMORY

The Regents of The Univer...

1. An adaptive method for reading a resistive memory, comprising:
applying a first sample pulse of voltage to a terminal of a resistive memory cell;
measuring a first resistance of the resistive memory cell, where the measuring takes place in response to the first sample
pulse;

applying a second sample pulse of voltage to the terminal of the resistive memory cell;
measuring a second resistance of the resistive memory cell, where the measuring takes place in response to the second sample
pulse;

determining a difference between the first resistance and the second resistance;
determining a logic state of the resistive memory cell from the difference; andapplying a correction pulse of voltage to the resistive memory cell, the correction pulse having a polarity opposite the sample
pulse.

US Pat. No. 9,096,625

BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME

THE REGENTS OF THE UNIVER...

1. A compound having a structural formula:

wherein the A ring is

X is selected from the group consisting of alkylene, alkenylene, cycloalkylene, cycloalkenylene, and heterocycloalkylene;
Y is selected from the group consisting of (CH2)n—N(Ra) and


Q is selected from the group consisting of O, O(CH2)1-3, NRc, NRc(C1-3alkylene), OC(?O)(C1-3alkylene), C(?O)O, C(?O)O(C1-3 alkylene), NHC(?O)(C1-3alkylene), C(?O)NH, and C(?O)NH(C1-3 alkylene);

Z is O or NRc;

R1 and R2, independently, are selected from the group consisting of H, CN, NO2, halo, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, heteroaryl, heterocycloalkyl, OR?, SR?, NR?R?, COR?, CO2R?, OCOR?, CONR?R?, CONR?SO2R?, NR?COR?, NR?CONR?R??, NR?C?SNR?R??, NR?SO2R?, SO2R?, and SO2NR?R?;

R3 is selected from a group consisting of H, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, heteroaryl, heterocycloalkyl,
OR?, NR?R?, OCOR?, CO2R?, COR?, CONR?R?, CONR?SO2R?, C1-3 alkyleneCH(OH)CH2OH, SO2R?, and SO2NR?R?;

R?, R?, and R??, independently, are H, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, heteroaryl, C1-3 alkyleneheterocycloalkyl, or heterocycloalkyl;

R4 is hydrogen, halo, C1-3alkyl, CF3, or CN;

R5 is hydrogen, halo, C1-3alkyl, hydroxyalkyl, or alkoxy;

R6 is selected from the group consisting of H, CN, NO2, halo, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, heteroaryl, heterocycloalkyl, OR?, SR?, NR?R?, CO2R?, OCOR?, CONR?R?, CONR?SO2R?, NR?COR?, NR?CONR?R??, NR?C?SNR?R??, NR?SO2R?, SO2R?, and SO2NR?R?;

R7 is selected form the group consisting of hydrogen, alkyl, alkenyl, (CH2)0-3cycloalkyl, optionally substituted with —OH(CH2)0-3cycloalkenyl, (CH2)0-3heterocycloalkyl, optionally substituted with —OH(CH2)0-3aryl, and (CH2)0-3heteroaryl;

R8 is selected form the group consisting of hydrogen, halo, NO2, CN, CF3SO2, and CF3;

Ra is selected from the group consisting of hydrogen, alkyl, heteroalkyl, alkenyl, hydroxyalkyl, alkoxy, cycloalkyl, cycloalkenyl,
and heterocycloalkyl;

Rb is hydrogen or alkyl;

Rc is selected from the group consisting of hydrogen, alkyl, hydroxyalkyl, and alkoxy; and

n, r, and s, independently, are 1, 2, 3, 4, 5, or 6;
or a pharmaceutically acceptable salt of (I), (II), or (III).

US Pat. No. 9,048,658

RESISTIVE SWITCHING FOR NON VOLATILE MEMORY DEVICE USING AN INTEGRATED BREAKDOWN ELEMENT

The Regents of The Univer...

1. A method for reading a memory cell, comprising:
providing a plurality of memory cells in an array, each of the memory cells comprising a switching device and an integrated
breakdown element, the integrated breakdown element being serially connected to the switching device;

applying a write voltage to a selected memory cell within the plurality of memory cells to cause the selected memory cell
to be in a write state; and

applying a read voltage to the selected memory cell, the read voltage being less than a sum of a plurality of breakdown voltages
and being less than the write voltage, the plurality of breakdown voltages being respectively associated with a plurality
of the integrated breakdown elements forming a sneak path among the memory cells associated with the plurality of integrated
breakdown elements.

US Pat. No. 9,544,764

CONTROLLING UNREGULATED AGGREGATION OF MOBILE APP USAGE

The Regents Of The Univer...

1. A method for controlling behavior tracking by applications executing on a mobile computing device, comprising:
managing, by a privacy manager, a set of profiles residing on the mobile computing device, each profile representing a different
isolated execution environment on the mobile computing device and defining a set of privacy rules governing an application
while executing in the associated execution environment;

prompting, by the privacy manager, a user to indicate a profile for a given application by presenting indicia for each of
the profiles in the set of profiles, where the prompting occurs prior to and contemporaneous with execution of the given application
in an execution environment on the mobile computing device;

receiving, by the privacy manager, an input from a user of the given application, the input indicating a profile selected
from the set of profiles; and

applying, by the privacy manager, the set of privacy rules associated with the selected profile to the given application during
execution of the given application,

prompting, by the privacy manager, the user to indicate a profile for a second application by presenting indicia for each
of the profiles in the set of profiles, where the prompting occurs prior to and contemporaneous with execution of the second
application in an execution environment on the mobile computing device;

receiving, by the privacy manager, an input from the user of the second application, the input indicating a second profile
selected from the set of profiles, where the second profile differs from the first profile; and

applying, by the privacy manager, the set of privacy rules associated with the selected second profile to the second application
during execution of the given application, where the privacy manager resides on the mobile computing device and is implemented
by computer readable instructions executed by a processor of the mobile computing device.

US Pat. No. 9,526,923

DISPOSABLE ACOUSTIC COUPLING MEDIUM CONTAINER

HISTOSONICS, INC., Ann A...

1. A method of providing ultrasound therapy to a patient, comprising the steps of:
placing a frame having an open aperture against the patient's skin;
filling the frame with an acoustic coupling medium so that the acoustic coupling medium directly contacts the patient's skin
through the open aperture;

inserting a rectal imaging probe into a rectum of the patient through a rectal sheath of the frame;
placing an ultrasound transducer in acoustic communication with the acoustic coupling medium;
imaging the patient's prostate with the rectal imaging probe; and
providing ultrasound therapy to the patient's prostate with the ultrasound transducer.

US Pat. No. 9,431,621

METAL OXIDE CHARGE TRANSPORT MATERIAL DOPED WITH ORGANIC MOLECULES

The Regents of the Univer...

1. A transparent metal oxide charge transport material for use in an optoelectronic device, the charge transport material
comprising:
a metal oxide material doped with an organic dopant material, wherein the organic dopant material is selected from the group
consisting of acridine orange base (AOB), and chloroboron subphthalocyanine (SubPc),

wherein the metal oxide material is doped with 1 to 20 vol. % of the organic dopant material, whereby electrical resistivity
of the metal oxide material is reduced while maintaining transparency of the metal oxide charge transport material.

US Pat. No. 9,084,546

CO-ELECTRODEPOSITED HYDROGEL-CONDUCTING POLYMER ELECTRODES FOR BIOMEDICAL APPLICATIONS

The Regents of the Univer...

1. A method of making a three-dimensional hydrogel-conducting polymer electrode for an implantable medical device, the method
comprising simultaneously electrodepositing a hydrogel and a conducting polymer on an electrode to form a three-dimensional
hydrogel-conducting polymer electrode.

US Pat. No. 9,562,484

RATE-BASED CONTRACTIVE MODEL PREDICTIVE CONTROL METHOD FOR INTERNAL COMBUSTION ENGINE AIR PATH CONTROL

The Regents of the Univer...

1. A system for controlling a variable geometry turbine and an EGR valve during engine operation, the system comprising:
an internal combustion engine; and
a controller configured to:
develop a non-linear model using engine operating parameters;
develop a linear quadratic model predictive controller, based on the non-linear model, for each engine operating zone; and
generate a rate based contractive predictive model based on the linear quadratic model, and use the rate based contractive
predictive model responsive to engine intake manifold pressure and EGR valve flow rate to generate requested engine turbine
lift and requested EGR flow rate.

US Pat. No. 9,503,196

N2 TIMES PULSE ENERGY ENHANCEMENT USING COHERENT ADDITION OF N ORTHOGONALLY PHASE MODULATED PERIODIC SIGNALS

The Regents Of The Univer...

1. A method for increasing energy in a pulse optical beam, comprising:
receiving an optical input beam having a periodic pulse train with a given repetition frequency;
splitting the input beam into N optical signals;
phase modulating each signal in the N optical signals at a different prescribed phase, such that the N optical signal are
orthogonal to each other; and

coherently combining each of the phase modulated signals into a single optical output beam by actively correcting phase errors
in each of the phase modulated signals, where a phase error is measured between phase of a given phase modulated signal and
a corresponding prescribed phase for the given phase modulated signal.

US Pat. No. 9,379,346

STACKED WHITE OLED HAVING SEPARATE RED, GREEN AND BLUE SUB-ELEMENTS

The Regents of the Univer...

1. An organic light emitting device comprising in order:
a cathode;
a green-emitting sub-element comprising an emissive layer comprising a phosphorescent green emissive material;
a charge-generating layer;
a blue-emitting sub-element comprising an emissive layer comprising a phosphorescent blue emissive material;
a charge-generating layer;
a red-emitting sub-element comprising an emissive layer comprising a phosphorescent red emissive material;
and an anode;
wherein a combined emission of the emitting materials gives a white emission from the device.

US Pat. No. 9,341,626

SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF

CYTOPHERX, INC., Ann Arb...

1. An extracorporeal device for treating inflammation in a subject, the device comprising:
(a) a housing defining a fluid inlet for receiving blood from a subject and a fluid outlet for returning the blood to the
subject after passing through the housing; and

(b) a plurality of hollow fibers disposed in parallel within the housing, each hollow fiber having a first end, a second end,
an interior surface defining an intracapillary space extending from the first end to the second end, and an exterior surface
in fluid communication with the fluid inlet and the fluid outlet for binding activated leukocytes and/or activated platelets
from the blood entering the housing via the fluid inlet, the exterior surfaces of the hollow fibers together defining a surface
area from about 0.2 m2 to about 2.0 m2 for binding activated leukocytes and/or activated platelets from the subject, the housing configured to (i) permit blood,
after entering the housing via the fluid inlet, to pass along the exterior surfaces of the hollow fibers as the blood moves
from the fluid inlet to the fluid outlet and (ii) create a shear force of less than 10 dynes/cm2 when fluid passes from the fluid inlet to the fluid outlet at a rate of from about 100 mL/minute to about 500 mL/minute; and

(c) a cap disposed on the housing to prevent fluid from entering the intracapillary space of the hollow fibers via their first
ends during operation of the device and precludes the attachment of a tube in fluid communication with the first end of the
hollow fibers.

US Pat. No. 9,270,086

ORGANIC LASER

The Regents of the Univer...

1. A device, comprising:
a first organic light emitting device, further comprising:
a first electrode;
a second electrode; and
an organic emissive layer disposed between the first electrode and the second electrode;
a first laser device, further comprising:
an optical cavity; and
an organic lasing material disposed within the optical cavity; and
a focus mechanism disposed to focus light emitted by an area of the first organic light emitting device onto an area of the
first laser device, such that the area of the first laser device is smaller than the area of the first organic light emitting
device.

US Pat. No. 9,207,171

METHODS FOR INCREASING TRANSMISSION THROUGH SCATTERING RANDOM MEDIA

THE REGENTS OF THE UNIVER...

1. A computer-implemented method for transmission of a wavefront through a medium, the computer-implemented method comprising:
refining, with one or more processors, the wavefront in each of one or more iterations, including:
transmitting, from a transmitter, a test wavefront into the medium;
receiving, at a detector, a measurement of the back-scatter from the test wavefront entering the medium;
determining, with one or more processors, whether the test wavefront achieves a numerically prespecified level of transmission
through the medium based upon the received back-scatter;

refining, with one or more processors, the test wavefront for transmitting into the medium in the next iteration based upon
the received back-scatter;

terminating the iterations when the numerically prespecified level of transmission through the medium is achieved;
modifying, with one or more processors, the wavefront based upon the final test wavefront; and
transmitting, from the transmitter, the modified wavefront through the medium.

US Pat. No. 9,184,400

METHODS OF MAKING ORGANIC PHOTOVOLTAIC CELLS HAVING IMPROVED HETEROJUNCTION MORPHOLOGY

The Regents Of The Univer...

1. A method of making a photovoltaic material by volatilization of a carrier through surface encapsulation and induced alignment,
the method comprising:
disposing a liquid precursor between a gas and solvent permeable layer and an electrode, the liquid precursor comprising an
organic electron donor material, an organic electron acceptor material, and the carrier comprising a solvent; and

applying pressure to the liquid precursor in a direction from the gas and solvent permeable layer through the liquid precursor
and towards the electrode and removing at least a portion of the carrier comprising the solvent through the gas and solvent
permeable layer to form a solid photovoltaic material comprising interpenetrating network domains of the organic electron
donor material and the organic electron acceptor material.

US Pat. No. 9,097,578

INFRARED SENSING USING PYRO/PIEZO-ELECTRIC RESONATORS

The Regents of The Univer...

1. An infrared sensor, comprising:
a resonant sensor element comprising a mechanical resonator and an IR absorber arranged to receive and absorb incident infrared
radiation, said resonator comprising a temperature-responsive material that exhibits pyroelectric and piezoelectric effects,
and said IR absorber being thermally coupled to said resonator such that said resonator receives thermal energy from at least
some of the incident infrared radiation absorbed by said IR absorber;

a first electrode and drive circuitry connected to said first electrode that applies an RF input signal to said first electrode
to excite said mechanical resonator; and

a second electrode and readout circuitry connected to said second electrode to measure one or more resonant characteristics
of said mechanical resonator;

wherein said resonator has at least one resonant characteristic that varies based on the amount of thermal energy received
from said IR absorber by said resonator.

US Pat. No. 9,653,709

OPTOELECTRONIC DEVICE FORMED WITH CONTROLLED VAPOR FLOW

The Regents of the Univer...

1. An organic optoelectronic device (OED), comprising:
a substrate having an OED cell support surface;
an OED cell located at an OED cell area along the support surface, the OED cell including a layer of vapor printed small-molecule
organic material arranged between first and second electrodes; and

a vapor flow barrier extending away from the support surface alongside the OED cell and arranged to contain the small-molecule
organic material within the OED cell area, wherein the layer of vapor printed small-molecule organic material is deposited
with a combination of processing conditions over the OED cell area along one side of the vapor flow barrier via a jet of gas
directed toward the support surface from a vapor printing nozzle, the jet of gas comprising the small-molecule organic material,
and

wherein the vapor flow barrier extends away from the support surface to a height that is sufficiently large to prevent the
small-molecule organic material from being deposited over the support surface at an opposite side of the vapor flow barrier
at the combination of processing conditions.

US Pat. No. 9,492,538

ISOLATION AND USE OF SOLID TUMOR STEM CELLS

The Regents of the Univer...

1. A method for obtaining a cellular composition comprising an enriched population of human CD44+CD24?/low solid tumor stem cells, the method comprising:
(a) obtaining an initial mixture of solid tumor stem cells and solid tumor cells from a human solid tumor of epithelial origin,
wherein the solid tumor is not from a cell line a primary tumor or a xenograft tumor established from a primary tumor; and

(b) separating a fraction of solid tumor stem cells from the mixture of solid tumor stem cells and solid tumor cells, wherein
the solid tumor stem cells are:

(i) CD44+;

(ii) CD24?/low;

(iii) enriched at least two-fold compared to the initial unfractionated mixture of solid tumor stem cells and solid tumor
cells; and

(iv) tumorigenic.

US Pat. No. 9,396,795

STORAGE DEVICE SUPPORTING LOGICAL OPERATIONS, METHODS AND STORAGE MEDIUM

The Regents of the Univer...

1. A storage device comprising:
a plurality of storage cells to store data values;
control circuitry to simultaneously couple at least two storage cells of the plurality of storage cells to at least one common
signal line, wherein the at least two storage cells comprise storage cells within a same column, and the at least one common
signal line comprises a pair of bitlines corresponding to the same column; and

sensing circuitry to sense a signal level on at least one of said at least one common signal line which is indicative of a
result of a logical operation applied to the data values stored in each of said at least two storage cells.

US Pat. No. 9,131,874

FLUOROSCOPY-INDEPENDENT, ENDOVASCULAR AORTIC OCCLUSION SYSTEM

THE REGENTS OF THE UNIVER...

1. A thoracic aortic occlusion system comprising:
an endovascular wire;
a balloon shaft comprising an aortic occlusion balloon on a distal end of the balloon shaft and a lumen to permit the balloon
shaft to pass over the endovascular wire when the endovascular wire and the balloon shaft are inserted into a femoral artery
at a femoral head of a patient; and

a nomogram comprising one of a table, chart or graph correlating distances between at least two external anatomical landmarks
of each human of a pool of humans to centerline distances from the femoral artery at the femoral head to a location within
a thoracic aorta of each of the humans, where a distance between at least two anatomical landmarks is measured on a patient
and compared to the distances between the at least two external anatomical landmarks on the nomogram to calculate a length
to which the endovascular wire and the balloon shaft are to be inserted in the patient such that the aortic occlusion balloon
is positioned at a desired location within the thoracic aorta without using fluoroscopy.

US Pat. No. 9,114,981

SURFACE PLASMON-MEDIATED ENERGY TRANSFER OF ELECTRICALLY-PUMPED EXCITONS

The Regents of The Univer...

1. An electrically pumped, multi-layer device that admits electrons and holes when powered by a power source and emits light,
the device comprising:
a first electrode;
a second electrode including an outer surface, said second electrode comprising a metal chosen from the group consisting of
silver, gold, platinum, and aluminum;

two active organic semiconductors disposed between the first and second electrodes;
a dye adjacent the outer surface of the metallic second electrode such that the second electrode is disposed between the dye
and the two active organic semiconductors; and

a dielectric capping layer adjacent the outer surface of the second electrode and the dye being doped within the dielectric
capping layer at a distance from the outer surface of the second electrode.

US Pat. No. 9,099,652

ORGANIC ELECTRONIC DEVICES WITH MULTIPLE SOLUTION-PROCESSED LAYERS

The Regents of the Univer...

1. A method of fabricating a tandem organic photosensitive device, the method comprising:
providing a substrate;
depositing a first conductive electrode layer over the substrate;
depositing a first layer of an electron donor type small molecule material film over the substrate by solution-processing
of the electron donor type small molecule material dissolved in a first solvent;

depositing a first layer of an electron acceptor type small molecule material over the first layer of the electron donor type
small molecule material film by a dry deposition process, resulting in an interim stack;

depositing a conductive layer over the interim stack by a dry deposition process;
depositing a second layer of the electron donor type small molecule material film over the conductive layer by solution-processing
of the electron donor type small molecule material dissolved in a second solvent, wherein the electron acceptor type small
molecule material and the conductive layer are insoluble in the second solvent;

depositing a second layer of an electron acceptor type small molecule material over the second layer of the electron donor
type small molecule material film by a dry deposition process, resulting in a stack; and

depositing a second conductive electrode layer over the stack.

US Pat. No. 9,068,977

NON-LINEAR ROTATION RATES OF REMOTELY DRIVEN PARTICLES AND USES THEREOF

THE REGENTS OF THE UNIVER...

1. A method of detecting the presence of an analyte in a sample, comprising:
contacting a magnetic particle with said sample under conditions such that said particle interacts with said analyte;
rotating said magnetic particle using an external rotating magnetic field applied to the sample;
measuring the non-linear rotation rate of said magnetic particle during application of the rotating magnetic field; and
determining the presence of said analyte in said sample when said non-linear rotation rate is altered relative to a rotational
rate of the magnetic particle in the absence of said sample.

US Pat. No. 10,000,134

WIRELESS CHARGING SYSTEM FOR CHARGING VEHICULAR BATTERY

DENSO International Ameri...

1. A wireless charging system for charging a battery in a vehicle, the vehicle includes a receiving coil positioned on an underside of the vehicle, the wireless charging system comprising:a coil charge device including a transmitting coil and a carriage, wherein the transmitting coil is positioned on the carriage;
a linear track extending across a designated path, wherein the coil charge device is positioned on and moveable along the linear track;
a linear motor operable to move the coil charge device along the linear track; and
a charge control module configured to control a position of the coil charge device along the designated path via the linear motor and operate the transmitting coil during a charge operation to charge the battery of the vehicle;
wherein the charge control module is configured to control the linear motor to position the coil charge device relative to the receiving coil such that an induced voltage across the receiving coil is at a maximum indicating that the charge coil device is aligned with the receiving coil.

US Pat. No. 9,813,936

SYSTEM AND METHOD FOR SCHEDULING TIME-SHIFTING TRAFFIC IN A MOBILE CELLULAR NETWORK

THE REGENTS OF THE UNIVER...

1. A system, comprising:
one or more processors; and
a memory that stores executable instructions that, when executed by the one or more processors, facilitate performance of
operations, comprising:

identifying an original data transfer request requesting a transfer of data to a mobile device via a mobile network, wherein
the original data transfer request occurs during a scheduling interval of a plurality of scheduling intervals, wherein each
scheduling interval of the plurality of scheduling intervals has a duration greater than a data transit time of the mobile
network;

identifying a quantity of data requested by the original data transfer request;
identifying a scheduling capacity of a candidate base station;
comparing the quantity of data requested to the scheduling capacity;
directing the candidate base station to deliver data to the mobile device during the scheduling interval, responsive to the
quantity of data requested being less than the scheduling capacity; and

deferring the original data transfer request to a subsequent scheduling interval of the plurality of scheduling intervals,
responsive to the quantity of data requested being greater than the scheduling capacity, wherein the deferring of the original
data transfer request to the subsequent scheduling interval of the plurality of scheduling intervals comprises resubmitting
the original data transfer request in the subsequent scheduling interval of the plurality of scheduling intervals.

US Pat. No. 9,627,614

RESISTIVE SWITCHING FOR NON VOLATILE MEMORY DEVICE USING AN INTEGRATED BREAKDOWN ELEMENT

The Regents of the Univer...

1. A method for forming a non-volatile memory device, comprising:
receiving a semiconductor substrate;
forming a first electrode structure in contact the semiconductor substrate;
depositing a rectifying structure in contact with the first electrode structure;
depositing an undoped resistive switching structure in contact with the rectifying structure; and
forming a second electrode structure in contact with the resistive switching structure, wherein the second electrode comprises
a plurality of metal particles;

wherein the non-volatile memory device is formed by a stack of materials including: the first electrode structure, the rectifying
structure, the resistive switching structure, and the second electrode structure.

US Pat. No. 9,606,124

METHODS OF DETECTING AND TREATING STEM-CELL CONTAINING SOLID TUMORS

The Regents of the Univer...

1. A method of detecting solid tumor stem cells, wherein the method comprises:
(i) obtaining cells from a tumor of a subject;
(ii) detecting cells that are positive for:
(a) at least one protein selected from the group consisting of CD44, CD24, ESA, ALDH, TPRXL, NOTCH2, RBM15, ST3GAL3, NFYA,
PCNX, TAS2R14, CD300LB, GIPC3, RAD51L1, ARID1B, EPPK1, COL11A2; KLK3, EIF2C2; ZFP41, FAM49B, and PSORS1C2 among said cells
from the tumor, or

(b) ALDH activity among said cells from the tumor; and
(iii) detecting cells that are positive for CXCR1 or FBXO21 among said cells from the tumor, wherein the detecting step for
cells positive for CXCR1 comprises the step of contacting said cells with Compound 1:


 and wherein the presence of cells positive for CXCR1 or FBXO21 and cells positive for at least one protein selected from
the group consisting of CD44, CD24, ESA, ALDH, TPRXL, NOTCH2, RBM15, ST3GAL3, NFYA, PCNX, TAS2R14, CD300LB, GIPC3, RAD51L1,
ARID1B, EPPK1, COL11A2; KLK3, EIF2C2; ZFP41, FAM49B, and PSORS1C2 or ALDH activity indicate the presence of solid tumor stem
cells in said tumor.

US Pat. No. 9,587,071

CONJUGATED GOLD NANOPARTICLES

THE REGENTS OF THE UNIVER...

1. A composition comprising: conjugated gold nanoparticles, wherein each of said conjugated gold nanoparticles comprise:
a) a gold nanoparticle comprising a gold surface,
b) a first type of attachment molecules attached to said gold nanoparticle at a density level below the saturation level for
said gold nanoparticle, wherein said first type of attachment molecules have the formula R1-polymer-R2,

wherein R1 is a moiety having affinity for said gold surface of said gold nanoparticle, and wherein R2 is a functional group
that allows attachment to other chemicals, and/or comprises a targeting ligand, and

c) a second type of attachment molecules attached to said gold nanoparticle, wherein said second type of attachment molecules
have the formula R3-polymer-R4, wherein R3 is a moiety having affinity for said gold surface of said gold nanoparticle, and
wherein R4 is a functional group that allows attachment to other chemicals, and/or comprises a targeting ligand, and

wherein either: A) said first type of attachment molecules possess a positive charge and said second type of attachment molecules
possess a negative charge, or B) said first type of attachment molecules possess a negative charge and said second type of
attachment molecules possess a positive charge, and

wherein said conjugated gold nanoparticle posses a ratio of negative to positive attachment molecules of 900/100 to 700/300.

US Pat. No. 9,505,781

COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF

The Regents of the Univer...

1. A compound of Formula 4b:

or a pharmaceutically acceptable salt thereof, wherein
each of R1, R7, R3, R4, R5, R6, R7, and R is independently H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkene, alkyne, heteroalkyl, alcohol,
diol, substituted diol, ether, amine, alkylamine, thiol, thioalkyl, halogen, carbocyclic ring, aryl, substituted aryl, heteroaryl,
substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, aldehyde; ketone, CO—(CH2)1-6—H, CO-ethenyl, CO-propenyl, CO-ethynyl, CO-propynyl, CO—(CH2)1-6-aryl, CO—(CH2)1-6-heteroaryl, CO—(CH2)1-3-trifluoromethane, CO—(CH2)1-6-cycloalkane, carboxylic acid, alkylcarboxylic acid, ester, alkylester, amide, CO-amino-dialkyl, alkylamide; sulfoxide, sulfone,
SO2—(CH2)1-6—H, SO2-alkenyl, SO2-alkynyl, SO2NH2, SO2—NH-alkyl, SO2-amino-dialkyl, sulfinic acid, cyano, alkylcyano, methylcarbonitrile, cyanate, thiocyanate, azide, or phosphate;

wherein R6 is present at one or more positions of the indole;

Y is N, C—H, or
Ra is alkyl, substituted alkyl, Amy, cycloalkyl, heteroalkyl, alkyl-substituted aryl, substituted aryl, aromatic heterocycle,
non-aromatic heterocycle, alcohol, ether, amine, cyano, sulfonyl, aldehyde, or aromatic group;

L is alkylene, oxalkylene, or absent; wherein when L is absent the bonds attached to L do not exist; and
each of E and G is independently N or C, wherein each of E and G is independently optionally substituted with R6.

US Pat. No. 9,498,571

NITRIC OXIDE DELIVERY DEVICES

The Regents of the Univer...

1. A nitric oxide delivery device, comprising:
a housing that is permeable to nitric oxide, the housing having a surface that is modified to detect surface charge or pH,
the housing defining an interior space;

a working electrode inside of the housing interior space, the working electrode being a copper-containing conductive material
or a base material coated with a copper-containing conductive material;

a reference/counter electrode inside of the housing interior space and electrically isolated from the working electrode; and
a source of nitrite ions contained within the housing interior space and in contact with the working electrode;
wherein the housing surrounds the working electrode, the reference/counter electrode, and the source of nitrite ions, and
separates the source of nitrite ions from an external environment.

US Pat. No. 9,490,744

OSCILLATOR REGULATION CIRCUITRY AND METHOD

The Regents of the Univer...

1. Oscillator regulation circuitry comprising:
control circuitry to generate an oscillator control signal for regulating a frequency of an output signal of an oscillator;
a first voltage regulating circuit to regulate an input voltage for providing different amounts of reference current to the
oscillator, wherein the first voltage regulating circuit comprises a first operational amplifier and a first transistor arranged
in series such that an output of the first operational amplifier is coupled to a gate of the first transistor, and wherein
the first transistor is coupled between an inverting input of the operational amplifier and the oscillator;

wherein the control circuitry comprises frequency sensing circuitry to sense the frequency of the output signal of the oscillator
and to generate a first signal dependent on the frequency of the output signal, wherein the frequency sensing circuitry comprises
at least one switched capacitor;

a second voltage regulating circuit to regulate the input voltage for charging the at least one switched capacitor, wherein
the second voltage regulating circuit comprises a second operational amplifier and a second transistor arranged in series
such that an output of the second operational amplifier is coupled to a gate of the second transistor, and wherein the second
transistor is coupled between the oscillator and an inverting input of the second operational amplifier; and

the control circuitry is to generate the oscillator control signal in dependence on a comparison between the first signal
and a non-oscillating reference signal.

US Pat. No. 9,415,123

POLYMERIC NANOPARTICLES FOR ULTRASOUND IMAGING AND THERAPY

THE REGENTS OF THE UNIVER...

1. A nanobubble comprising an amphiphilic ABC triblock copolymer, wherein:
block A comprises a hydrophilic polymer,
block B comprises a crosslinking polymer, and
block C comprises a hydrophobic copolymer comprising
methyl methacrylate (MMA) and
a fluorinated monomer,
wherein the fluorinated monomer is present in the hydrophobic copolymer of block C at 25 mole percent or less, wherein the
hydrophobic copolymer has a number average molecular weight of about 3 kDa to about 12.5 kDa,

or a nanobubble produced from micellization of the amphiphillic ABC triblock copolymer.

US Pat. No. 9,409,780

NANOSTRUCTURES PATTERNED BY ELECTROSTATIC PRINTING

The Regents of the Univer...

1. A method, comprising the step of: depositing particles comprising a nanostructure catalyst onto a substrate in an electrostatically
defined growth pattern, wherein the substrate is a transfer substrate and the method further comprises the step of transferring
at least a portion of the particles to a growth substrate.

US Pat. No. 9,811,760

ONLINE PER-FEATURE DESCRIPTOR CUSTOMIZATION

FORD GLOBAL TECHNOLOGIES,...

1. An image processing system comprising:
a processor having a memory storing computer-executable instructions, wherein the processor is programmed to:
define a first descriptor in a first image;
generate a mask from the first image;
define a second descriptor in a second image, wherein the first descriptor includes a plurality of first test points and wherein
the second descriptor includes a plurality of second test points;

compare the first descriptor to the second descriptor to define a first error vector;
determine a second error vector by applying the mask, wherein the mask reduces the plurality of first test points to a subset
of the plurality of first test points based at least in part on a robustness to viewpoint change of each of the plurality
of first test points; and

determine an error between the first descriptor and the second descriptor using the second error vector.
US Pat. No. 9,568,476

DIAGNOSIS AND TREATMENT OF BREAST CANCER

THE REGENTS OF THE UNIVER...

1. A method for determining a treatment course of action, comprising
a) detecting the level of circulating tumor cells (CTC) in a sample from a subject with breast cancer using staining and an
immunoassay;

b) measuring the level of expression of estrogen receptor, HER-2, bcl-2, and ki67 on said CTC using a detection method selected
from the group consisting of an immunoassay, nucleic acid amplification, and nucleic acid hybridization;

c) calculating a numerical CTC-Endocrine Therapy Index (CTC-ETI) based on said number of CTC positive for expression of said
estrogen receptor, HER-2, bcl-2, ki67, and total number of CTC, wherein said CTC-ETI is calculated by i) assigning zero points
when the number of CTC is 0-4 per 7.5 ml, 1 point when the number of CTC is 5-10 per 7.5 ml, and 2 points when the number
of CTC is greater than 10 per 7.5 ml; ii) assigning zero points when the number of CTC positive for estrogen receptor is greater
than 10%, assigning 2 point when the number of CTC positive for estrogen receptor is 1-10%, and assigning 6 points when the
number of CTC positive for estrogen receptor is zero; iii) assigning zero points when the number of CTC positive for HER-2
is 0%, assigning 1 point when the number of CTC positive for HER-2 is 1-10%, and assigning two points when the number of CTC
positive for HER-2 is greater than 10%; iv) assigning zero points when the number of CTC positive for bcl-2 is greater than
10%, assigning 1 point when the number of CTC positive for bcl-2 is 1-10%, and assigning 2 points when the number of bcl-2
is 0%; v) assigning zero points when the number of CTC positive for ki67 is 0%, assigning 1 point when the number of CTC positive
for Ki-67 is 1-10%, and assigning 2 points when the number of CTC positive for Ki-67 is greater than 10%; and vi) adding said
points to obtain said CTC-ETI; and

d) administering an anti-estrogen therapy selected from the group consisting of a selective estrogen receptor modulator (SERM)
and an aromatase inhibitor when said CTC-ETI is between 0 and 6 and administering chemotherapy when said CTC-ETI is between
7 and 14.

US Pat. No. 9,557,223

MACH-ZEHNDER INTERFEROMETER HAVING A DOUBLY-CORRUGATED SPOOFED SURFACE PLASMON POLARITON WAVEGUIDE

The Regents Of The Univer...

1. A Mach-Zehnder interferometer, comprising:
an input configured to receive an input electromagnetic (E-M) wave having a frequency on the order of one terahertz;
a first arm extending from the input and configured to guide a spoofed surface plasmon polariton (SSPP) wave therethrough,
where the SSPP wave propagates at a speed slower than the input E-M wave;

a second arm extending from the input in parallel with the first arm and configured to guide a spoofed surface plasmon polariton
(SSPP) wave, where the SSPP wave propagates at a speed slower than the input E-M wave and the refractive index of the first
arm differs from the refractive index of the second arm; and

an output configured to receive the SSPP waves from each of the first arm and the second arm and form an interference wave
therein.

US Pat. No. 9,517,241

AMELIORATION OF INTESTINAL FIBROSIS AND TREATMENT OF CROHN'S DISEASE

The Regents Of The Univer...

1. A method of ameliorating intestinal fibrosis in a subject, the method comprising administering to the subject a composition
comprising a compound of Formula (I)

wherein Et is ethyl,
wherein the dashed line indicates a single bond or a double bond in the E configuration between carbon 22 and carbon 23, and
wherein the configuration at carbon 24 to which Et is attached is in the R configuration or the S configuration.

US Pat. No. 9,429,627

ELECTRONIC DEVICE WITH SUPERVISOR CIRCUIT FOR DETECTING RESISTANCE PARAMETER OF AN ENERGY STORAGE DEVICE

The Regents of the Univer...

1. An electronic device comprising:
an energy storage device;
circuitry supplied with a storage device voltage from the energy storage device; and
a supervisor circuit configured to enable the circuitry in response to the storage device voltage exceeding an enable threshold
voltage;

wherein the supervisor circuit is configured to detect a resistance parameter indicative of an internal resistance of the
energy storage device and to adjust the enable threshold voltage based on the resistance parameter;

wherein the supervisor circuit comprises a test current generator configured to draw a test current from the energy storage
device for testing the internal resistance of the energy storage device; and

wherein the test current generator comprises a plurality of capacitors and a plurality of switches for selecting whether the
capacitors are coupled in parallel or coupled in series across the energy storage device.

US Pat. No. 9,316,623

MICRO-SCALE PASSIVE VAPOR PRECONCENTRATOR/INJECTOR

The Regents Of The Univer...

1. A passive preconcentrator and injector device, comprising:
an upper portion defining an array of micro-scale diffusion channels;
a lower portion defining a cavity in fluid communication with the micro-scale diffusion channels;
a collection material disposed within the cavity and configured to capture at least one gas-phase analyte;
an integral heating unit disposed in thermal communication with the lower portion and configured to heat the cavity;
an inlet port and an outlet port in fluid communication with the cavity; and
a fluidic manifold system disposed between the cavity and the outlet port, the fluidic manifold system comprising a plurality
of conduits in fluid communication with and configured to concurrently extract desorbed analyte(s) from a plurality of regions
of the cavity, wherein the device is configured to collect at least one compound in a gas phase at a known rate by using passive
diffusion, without the use of artificial circulation, and subsequently remove the compound for injection to a measuring device.

US Pat. No. 9,242,067

PERSONALIZED AUDITORY-SOMATOSENSORY STIMULATION TO TREAT TINNITUS

THE REGENTS OF THE UNIVER...

20. A system for treating an auditory condition in a subject, the system being capable of stimulating (i) a somatosensory
system of the subject with a generated somatosensory stimulation signal and (ii) an auditory system of the subject with an
audible stimulation signal, the system comprising:
a bimodal stimulation system having an audible signal generator, a somatosensory signal generator, a processor, and a memory,
wherein the processor is operatively coupled to the audible signal generator and the somatosensory signal generator to control
each, and wherein the bimodal stimulation system is configured to,

generate, in the audible signal generator, the audible stimulation signal having a first firing point and first firing period,
stimulus onset, and/or duration, and

generate, in the somatosensory signal generator, the somatosensory stimulation signal to stimulate a somatosensory system
of a subject, the somatosensory stimulation signal having a second firing point and second firing period, stimulus onset,
and/or duration,

wherein the memory stores instructions that when executed by the processor cause the processor to:
establish a timing order and timing difference between the first firing point and the second firing point to reduce the auditory
condition, wherein the first firing period and the second firing period are to be maintained asynchronously to reduce the
auditory condition so that the onset of the first firing period does not overlap the onset of the second firing period.

US Pat. No. 9,200,689

SINGLE-AXIS FLEXURE BEARING CONFIGURATIONS

The Regents of The Univer...

1. A flexure bearing configuration, comprising:
a primary mover guided for movement along a motion axis;
a first flexure connection coupled to said primary mover;
a first secondary mover guided for movement along the motion axis and coupled to said first flexure connection;
a second flexure connection coupled to said first secondary mover, said second flexure connection being anchored at a ground;
a third flexure connection coupled to said primary mover;
a second secondary mover guided for movement along the motion axis and coupled to said third flexure connection; and
a fourth flexure connection coupled to said second secondary mover, said fourth flexure connection being anchored at said
ground;

wherein, during use, a displacement along the motion axis of said first secondary mover, of said second secondary mover, or
of both said first and second secondary movers, is approximately one-half a displacement along the motion axis of said primary
mover, and the displacement of said first secondary mover, of said second secondary mover, or of both said first and second
secondary movers, remains approximately one-half throughout movement of said primary mover during use of the flexure bearing
configuration; and

wherein said primary mover is free of a direct coupling to a flexure connection that is not directly coupled to a secondary
mover.

US Pat. No. 9,197,981

COORDINATION AMONGST HETEROGENEOUS WIRELESS DEVICES

The Regents Of The Univer...

1. A method for coordinating communication amongst wireless communication devices in a wireless network, comprising:
receiving, at a receive device, a data packet via a wireless communication link from a transmit device;
detecting, by the receive device, a preamble of the data packet, the preamble comprised of a sequence of energy pulses, where
energy pulses are separated by a gap and duration of a single the gap in the sequence of pulses encodes coordination data
for the receive device, each energy pulse in the sequence of pulses has a length and is comprised of a plurality of data samples,
where each pulse includes at least D samples and D is a ratio of a clock rate of the transmit device to a clock rate of the
receive device;

extracting, by the receive device, the coordination data from the preamble of the data packet; and
coordinating, by the receive device, communication between the transmit device and the receive device using the coordination
data.

US Pat. No. 9,147,443

LOW POWER REFERENCE CURRENT GENERATOR WITH TUNABLE TEMPERATURE SENSITIVITY

The Regents Of The Univer...

1. A circuit for generating a reference current, said circuit comprising:
a voltage difference generator configured to receive an input voltage and operable to supply a first voltage and a second
voltage with a difference between them and derived from the input voltage, where the first voltage and the second voltage
have predefined values that are substantially insensitive to changes in the input voltage, said voltage difference generator
comprising:

a reference voltage generator adapted to supply a first supply voltage;
a voltage buffer amplifier electrically coupled to said first supply voltage and adapted to provide a second supply voltage;
and

a voltage ladder electrically coupled to said second supply voltage and adapted to supply said first voltage and said second
voltage;

a first buffer electrically coupled to said first voltage, said first buffer being adapted to supply a third voltage, said
first buffer comprising:

a first amplifier adapted to:
receive said first voltage;
receive said third voltage; and
compare said first voltage to said third voltage, and, in response, to output a first control voltage; and
a first transistor device adapted to receive said first control voltage, and, in response, to supply said third voltage;
a second buffer electrically coupled to said second voltage, said second buffer being adapted to supply a fourth voltage,
said second buffer comprising:

a second amplifier adapted to:
receive said second voltage;
receive said fourth voltage; and
compare said second voltage to said fourth voltage, and, in response, to output a second control voltage; and
a second transistor device adapted to receive said second control voltage, and, in response, to supply said fourth voltage;
and

a resistive element having a substantially linear operating behavior and electrically coupled between said third voltage and
said fourth voltage, said resistive element being adapted to generate a reference current that is a function of said third
voltage and said fourth voltage; and

a current mirror electrically connected in series with the resistive element, said current mirror being adapted to mirror
the reference current, wherein the first buffer, the second buffer and the current mirror are comprised of transistors operating
solely in a sub-threshold region.

US Pat. No. 9,514,074

SINGLE CYCLE ARBITRATION WITHIN AN INTERCONNECT

The Regents of the Univer...

1. Interconnect circuitry for providing a communication path for data between a selected one of N signal inputs and a signal
output, where N is an integer of two or more, said interconnect circuitry comprising:
multiplexing circuitry configured to select one of said N signal inputs as a selected signal input in dependence upon a selection
signal and to connect said selected signal input to said signal output to send given data; and

arbitration circuitry configured to generate said selection signal so as to perform an arbitration in a single cycle between
a plurality of said N signal inputs having respective data to send, wherein

said arbitration is performed in dependence upon:
(i) respective values of a first arbitration parameter associated with each of said plurality of said N signal inputs; and
(ii) when two or more of said plurality of said N signal inputs have a common value of said first arbitration parameter, a
second arbitration parameter associated with each of said two or more of plurality of said N signal inputs, said second arbitration
parameter having a different value for each of said two or more of said plurality of said N signal inputs.

US Pat. No. 9,130,170

INVERTED ORGANIC PHOTOSENSITIVE DEVICE

The Regents of the Univer...

1. An inverted photosensitive device comprising:
a surface-treated reflective electrode comprising stainless steel foil;
an organic donor-acceptor heterojunction over said reflective electrode; and
a transparent electrode over said donor-acceptor heterojunction.

US Pat. No. 9,943,708

AUTOMATED CONTROL OF MICROMANIPULATOR ARM FOR HISTOTRIPSY PROSTATE THERAPY WHILE IMAGING VIA ULTRASOUND TRANSDUCERS IN REAL TIME

HISTOSONICS, INC., Ann A...

1. An imaging and therapy system comprising:a micro-manipulator system;
an ultrasound therapy system supported by the micro-manipulator system, the ultrasound therapy system comprises a histotripsy system that is configured to generate a cavitation bubble cloud in a target tissue volume; and
an imaging system supported by the micro-manipulator system apart from the ultrasound therapy system and configured to monitor the cavitation bubble cloud in the target tissue volume in real time;
wherein the micro-manipulator system comprises a control system configured to automatically position and move the imaging system and the ultrasound therapy system, wherein the control system is further configured to locate a focal point of the ultrasound therapy system which is positioned a distance of 0.8 cm to 4 cm from the imaging system and further configured to ablate desired tissue within the target tissue volume by retrieving images from the imaging system and identify a desired treatment volume; and
wherein the control system comprises a computer that is configured to independently control relative movement of the ultrasound therapy system and the imaging system, and further configured to automatically maintain the cavitation bubble cloud generated by the ultrasound therapy system within a field of view of the imaging system;
wherein the micro-manipulator is adapted and configured to position the imaging system within a return of a human male patient and further configured to position the ultrasound therapy system in acoustic contact with a perineum of the patient while the imaging system is in the rectum; and
wherein the ultrasound therapy system comprises an ultrasound therapy transducer configured to deliver acoustic pulses that is configured to operate at a frequency between 50 KHz and 5 MHz, having a pulse intensity with a peak negative pressure between 8 MPa to 40 MPa, a peak positive pressure between 10 MPa to 500 MPa, a pulse length shorter than 50 cycles, a duty cycle of less than 5%, and a pulse repetition frequency between 100 hz to 5 KHz.
US Pat. No. 9,926,372

METHODS AND COMPOSITIONS FOR MODULATION OF BLOOD-NEURAL BARRIER

Ludwig Institute for Canc...

1. A method for treating stroke in an animal in need of such treatment comprising administering to said animal an effective amount of an anti-platelet derived growth factor receptor-? antibody.

US Pat. No. 9,515,275

INVERTED ORGANIC PHOTOSENSITIVE DEVICES

THE REGENTS OF THE UNIVER...

1. An inverted photosensitive device comprising:
a reflective substrate;
a surface-treated transparent electrode over the reflective substrate;
an organic donor-acceptor heterojunction over said surface-treated transparent electrode; and
an electrode over said donor-acceptor heterojunction,
wherein the inverted photosensitive device is an organic solar cell.
US Pat. No. 9,144,565

METHOD FOR TREATING HEARING LOSS

THE REGENTS OF THE UNIVER...

1. A method of treating hearing loss, said method comprising the step of internally administering a composition to the mammal,
wherein the composition consists essentially of a biologically effective amount of vitamin A, vitamin E, vitamin C, a vasodilator
comprising magnesium, and, optionally, a withanolide, and/or resveratrol.
US Pat. No. 9,072,813

MINERALIZATION AND BIOLOGICAL MODIFICATION OF BIOMATERIAL SURFACES

THE REGENTS OF THE UNIVER...

1. A method for controlling mineralization of a biomaterial surface, comprising
functionalizing at least a first surface of a biomaterial by at least one of: chemical hydrolysis, electrolysis, or electromagnetic
radiation; and

contacting the functionalized biomaterial surface with an amount of a mineral-containing solution effective to form a mineralized
biomaterial that comprises an extended, mineral coating at the functionalized biomaterial surface;

said biomaterial comprising at least a first porous, biodegradable polymer portion that has an interconnected pore structure
and that is degradable over a controllable time scale,

wherein the polymer portion of the biomaterial is a poly(alpha-hydroxy acid),
wherein the poly(alpha-hydroxy acid) is a polylactic acid polymer, a polyglycolic acid polymer or a polylactic-co-glycolic
acid copolymer, and

wherein the functionalization provides for specific control over the mineral coating on the biomaterial surface.

US Pat. No. 9,868,736

DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME

THE REGENTS OF THE UNIVER...

1. A compound having a formula (I):
wherein
R1 and R2 together form an optionally substituted aryl ring or heteroaryl ring, and R3 is halo or hydrogen;

R4 is C2-C6alkyl or C1-C6alkylenearyl; and

(a) one of R5 and R5? is hydrogen and the other substituted alkoxy, or (b) each of R5 and R5? is substituted alkoxy, or (c) when the ring formed by R1 and R2 together is an aryl ring which is substituted, or is a heteroaryl ring which is optionally substituted, then R5 and R5? can each be hydrogen;
or a salt or solvate thereof.
US Pat. No. 9,068,163

METHODS AND COMPOSITIONS FOR GROWTH OF EMBRYONIC STEM CELLS

The Regents of the Univer...

1. A method for culturing human pluripotent stem cells comprising:
a) applying human pluripotent stem cells to a substrate, wherein said substrate comprises poly[2-(methacryloyloxy)ethyl dimethyl(3-sulfopropyl)ammonium]
(PMEDSAH); and

b) growing said human stem cells on said substrate in the presence of culture media capable of maintaining said cells.