US Pat. No. 9,561,063

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE

SI-Bone Inc., San Jose, ...

1. A joint fusion device comprising:
an elongated bone fusion device having a proximal end, a distal end, a longitudinal axis and a substantially triangular cross
section transverse to the longitudinal axis and free of external screw threads and being sized and configured for placement
in association with and non-parallel to a joint between individual first and second bone segments in response to an axially
applied, non-rotational force, the elongated bone fusion device including a lumen extending through the length of the elongated
bone fusion device from the proximal end to the distal end and oriented parallel to the longitudinal axis to accommodate passage
over a guide pin during placement and an exterior surface treated to provide bony in-growth upon placement, wherein the exterior
surface has a rough surface texture, wherein the distal end includes a beveled distal tip.

US Pat. No. 9,486,264

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE USING COMPRESSIVE IMPLANTS

SI-Bone Inc., San Jose, ...

1. A method for the fixation or fusion of the sacroiliac joint, the method comprising:
creating an insertion path through the ileum, across the sacroiliac joint, and into the sacrum;
shaping the insertion path with a broach having a triangular cross section
inserting a compressive implant having a longitudinal axis through the insertion path into the ileum, through the sacroiliac
joint, and into the sacrum, the compressive implant comprising an anchor body having a distal end with an external screw thread
and an elongated implant structure configured to be coaxially disposed over a proximal portion of the anchor body;

anchoring the distal end of the anchor body in an interior region of the sacrum before compressing the sacroiliac joint;
advancing the elongated implant structure coaxially over the proximal portion of the anchor body;
abutting a washer against an exterior surface of the ileum, the washer disposed coaxially over a proximal portion of the compressive
implant; and

compressing the sacroiliac joint.

US Pat. No. 9,044,321

INTEGRATED IMPLANT

SI-Bone Inc., San Jose, ...

1. A bone fusion implant comprising:
a core having a hollow structure formed by a multi-sided wall;
a delivery pin hole within the core extending from a proximal end to a distal end of the core, the delivery pin hole configured
to securely receive a delivery pin; and

a plurality of cutting edges at a distal end of the multi-sided wall, the plurality of cutting edges configured to cut through
bone; wherein the multi-sided wall comprises a plurality of interlocking wall sections, the wall sections configured to be
implanted independently and interlocked after insertion into a patient.

US Pat. No. 9,375,323

APPARATUS, SYSTEMS, AND METHODS FOR ACHIEVING TRANS-ILIAC LUMBAR FUSION

SI-Bone Inc., San Jose, ...

1. A method for trans-iliac lumbar fusion, the method comprising:
creating an insertion path from an anterolateral region of a lumbar vertebra L5, in a caudal direction through the intervertebral
disc into and through an opposite anterolateral interior region of a sacral vertebra S1, through the sacro-iliac joint, and
terminating in the ilium;

providing a bone fixation implant comprising an elongated implant structure; and
inserting the bone fixation implant through the insertion path from the anterolateral region of a lumbar vertebra L5, in a
caudal direction through the intervertebral disc into and through the opposite anterolateral interior region of a sacral vertebra
S1, through the sacro-iliac joint, and terminating in the ilium.

US Pat. No. 9,492,201

APPARATUS, SYSTEMS AND METHODS FOR ACHIEVING ANTERIOR LUMBAR INTERBODY FUSION

SI-Bone Inc., San Jose, ...

1. A method for anterior lumbar interbody fusion, the method comprising:
creating a first insertion path from a first anterolateral region of a selected lumbar vertebra in a caudal direction across
an intervertebral disc into a first opposite anterolateral region of an adjacent lumbar vertebra, wherein the first anterolateral
region and the first opposite anterolateral region are on opposite lateral sides of the spine;

providing a first bone fixation implant comprising an elongated implant structure having a longitudinal axis and a cross-sectional
profile transverse to the longitudinal axis that is defined by at least one apex, the cross-sectional profile extending from
a proximal portion of the elongated implant structureto a distal portion of the elongated implant structure, wherein the elongated
implant structure comprises an exterior surface region treated to provide bony in-growth or through-growth along the implant
structure; and

inserting the first bone fixation implant through the insertion path laterally from the first anterolateral region of the
selected lumbar vertebra in a caudal direction across the intervertebral disc into the first opposite anterolateral region
of the adjacent lumbar vertebra.

US Pat. No. 9,820,789

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE

SI-BONE INC., San Jose, ...

1. A method for the fixation or fusion of a first bone segment to a second bone segment across a joint, the method comprising:
providing an elongate metal implant having a proximal end, a distal end, a longitudinal axis, an external screw thread, and
a lumen extending through the elongate implant along the longitudinal axis, wherein the elongate implant has a tapered distal
end and a first fenestration positioned on a middle portion of elongate implant such that the first fenestration is offset
from both the distal end and the proximal end;

inserting the elongate implant through the first bone segment and across the joint and into the second bone segment such that
the elongate implant traverses the joint at an oblique angle;

providing a second elongate metal implant having a proximal end, a distal end, a longitudinal axis, an external screw thread,
and a lumen extending through the second elongate implant along the longitudinal axis of the second elongate implant, wherein
the second elongate implant has a tapered distal end; and

inserting the second elongate implant through the first bone segment and across the joint and into the second bone segment;
wherein the second elongate implant is inserted across the joint at an oblique angle.

US Pat. No. 9,662,128

SYSTEMS AND METHODS FOR THE FUSION OF THE SACRAL-ILIAC JOINT

SI-Bone Inc., San Jose, ...

1. A method of forming a bore in the ileum, across the sacroiliac joint, and into the sacrum to receive an implant having
a cross-sectional profile defined by a plurality of apices, the method comprising:
inserting a guide pin into the ileum, across the sacroiliac joint, and into the sacrum;
disposing a drill bit over the guide pin, the drill bit having a longitudinal axis and a cross-sectional profile transverse
to the longitudinal axis of the drill bit, the drill bit having a lumen configured to receive the guide pin;

drilling a bore along the guide pin with the drill bit, the bore extending from the ileum, across the sacroiliac joint, and
into the sacrum;

removing the drill bit from the guide pin;
disposing a broach over the guide pin, the broach having longitudinal axis and a cross-sectional profile transverse to the
longitudinal axis of the broach that is defined by a plurality of apices and that matches in shape the cross-sectional profile
of the implant, the broach having a lumen configured to receive the guide pin, wherein the cross-sectional profile of the
broach is larger than the cross-sectional profile of the drill bit; and

shaping the bore with the broach such that the cross-sectional profile of the bore matches the shape of the cross-sectional
profile of the implant, wherein the step of shaping the bore with the broach comprises advancing the broach along the guide
pin from the ileum, across the sacroiliac joint, and into the sacrum.

US Pat. No. 9,662,157

MATRIX IMPLANT

SI-Bone Inc., San Jose, ...

1. A modular implant for the fixation or fusion of the SI-Joint, the modular implant comprising:
a distal portion comprising a frame, the frame joined to a distal guide pin receptacle and to a plurality of transverse support
struts arranged in a rectilinear configuration;

a proximal portion comprising a frame joined to a proximal guide pin receptacle and to a plurality of transverse support struts
arranged in a rectilinear configuration; and

at least one repeating internal portion comprising:
a plurality of apex struts joined together by oblique support struts arranged in an oblique configuration between the apex
struts,

a plurality of transverse support struts arranged perpendicularly to the apex struts, the plurality of transverse support
struts arranged in a rectilinear configuration at both a proximal end and a distal end of the repeating internal portion,
and

an internal guide pin receptacle secured to the oblique support struts and/or transverse support struts and aligned with both
the distal guide pin receptacle and the proximal guide pin receptacle;

wherein the at least one internal repeating portion is positioned between the distal portion and the proximal portion such
that the transverse support struts of the distal portion are aligned with a first set of transverse support struts of the
repeating internal portion and the transverse support struts of the proximal portion are aligned with a second set of transverse
support struts of a repeating internal portion.

US Pat. No. 9,743,969

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE

SI-Bone Inc., San Jose, ...

1. A method comprising:
identifying a bone site comprising a first bone segment, a second bone segment, and a joint between the first and second bone
segments;

providing an elongated bone fusion device having a longitudinal axis and a rectilinear cross section transverse to the longitudinal
axis and including an exterior surface treated to provide bony in-growth;

forming a bore having a longitudinal axis in the first bone segment;
forming a bore having a longitudinal axis in the second bone segment that faces the bore in the first bone segment across
the joint, the bores in the first and second segments each being non-parallel to the joint and having a rectilinear cross-sectional
profile sized and configured to tightly engage the exterior surface of the elongated bone fusion device, wherein the rectilinear
cross-sectional profile of each bore is transverse to the longitudinal axis of each bore; and

fusing the joint by inserting the elongated bone fusion device across the joint and into tight engagement within the bores
of the first and second bone segments, to thereby restrict movement of the elongated bone fusion device across the joint and
provide bony in-growth within the bores along the exterior surface of the bone fusion device.

US Pat. No. 9,839,448

IMPLANT PLACEMENT

SI-Bone Inc., San Jose, ...

1. A method of implanting a plurality of implants across an SI-joint, the method comprising:
identifying a plurality of anatomical landmarks in the lateral view including the alar line, the posterior sacral body line,
the anterior sacral body line, and the anterior cortex of the sacral alar;

inserting a plurality of guide pins across an anterior portion of the SI-joint and through hyaline cartilage, wherein the
plurality of guide pins are inserted with reference to at least one anatomical landmark;

creating a bore around each of the plurality of guide pins; and
inserting an implant into each bore such that each implant crosses the anterior portion of the SI-joint and passes through
hyaline cartilage, wherein at least one guide pin and implant are inserted anterior of the anterior sacral body line in the
lateral view.

US Pat. No. 9,662,158

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE AT OR NEAR A SACROILIAC JOINT

SI-BONE INC., San Jose, ...

1. A joint fusion device, the joint fusion device comprising:
an elongated, stem-like device having a triangular cross section free of external screw threads and lateral fenestrations,
the device being sized and configured for placement to fuse a sacroiliac joint, which lies between an iliac bone and a sacrum,
in response to an axially applied, non-rotational force, the elongated, stem-like device having an exterior surface treated
to provide bony in-growth and/or on-growth upon placement, wherein the elongated, stem-like device is formed from one or more
materials selected from a group consisting of titanium, titanium alloys, tantalum, chrome cobalt, and surgical steel, wherein
the triangular cross section of the elongated, stem-like device is configured to inhibit movement of the sacroiliac joint
without the use of an additional component transversely intersecting the device through a lateral fenestration, wherein the
elongated, stem-like device has a minimum length greater than a thickness of the iliac bone at the sacroiliac joint.

US Pat. No. 9,622,783

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE

SI-BONE INC., San Jose, ...

1. A method for the fixation or fusion of a first bone segment to a second bone segment across a joint, the method comprising:
providing an elongate implant having a proximal end, a distal end, a longitudinal axis, a lumen extending through the elongate
implant along the longitudinal axis, and a cross-sectional profile transverse to the longitudinal axis that is defined by
at least three apices joined together by at least three sides, wherein the elongate implant has a first fenestration having
a proximal end and a distal end, the first fenestration positioned on a middle portion of the elongate implant such that the
first fenestration is offset from both the distal end and the proximal end, wherein the elongate implant is free from external
screw threads;

creating a noncircular bore through the first bone segment and into the second bone segment before inserting the elongate
implant through the first bone segment, the noncircular bore having a cross-sectional profile defined by at least three apices
joined together by at least three sides that matches the cross-sectional profile of the elongate implant; and

inserting the elongate implant into the noncircular bore through the first bone segment and transversely across the joint
and into the second bone segment by applying an axially directed force to the elongate implant, wherein the elongate implant
is inserted transversely across the joint such that the first fenestration lies at least partly in the joint between the first
bone segment and the second bone segment.

US Pat. No. 9,936,983

IMPLANTS FOR SPINAL FIXATION OR FUSION

SI-Bone Inc., San Jose, ...

1. A method for stabilizing a first bone segment and a second bone segment of a patient, the method comprising:implanting a first implant into the first bone segment, the first implant comprising a stem portion configured to be inserted into the first bone segment and a tulip portion for receiving a rod;
implanting a second implant into the second bone segment, the second implant comprising a stem portion configured to be inserted into the second bone segment and a tulip portion for receiving the rod, the stem portion of the second implant having a rectilinear cross section transverse to a longitudinal axis of the stem portion of the second implant wherein the stem portion of the second implant is straight; and
securing a rod to both the tulip portion of the first implant and the tulip portion of the second implant.

US Pat. No. 10,004,547

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE AT OR NEAR A SACROILIAC JOINT

SI-BONE INC., Santa Clar...

1. A method for a fixation or fusion of a sacroiliac joint, the method comprising:inserting an implant though an ilium, across the sacroiliac joint, and into a sacrum, wherein the implant comprises an elongate body having a longitudinal axis and a cross-sectional profile transverse to the longitudinal axis that is defined by at least one apex; and
advancing the implant between an S1 and an S2 foramina and into an S2 vertebral body.

US Pat. No. 9,956,013

SYSTEMS AND METHODS FOR THE FIXATION OR FUSION OF BONE

SI-BONE INC., San Jose, ...

1. A method for the fixation or fusion of a first bone segment to a second bone segment across a joint, the method comprising:providing an elongate implant having a proximal end, a distal end, a longitudinal axis, a lumen extending through the elongate implant along the longitudinal axis, and a cross-sectional profile transverse to the longitudinal axis that is defined by at least one apex, wherein the elongate implant is free from external screw threads; and
inserting the elongate implant through the first bone segment and transversely across the joint and into the second bone segment by applying an axially directed force to the elongate implant, such that the distal end of the elongate implant is inserted into the second bone segment and the proximal end of the elongate implant remains within the first bone segment;
wherein the first bone segment and/or the second bone segment is a vertebra.

US Pat. No. 9,949,843

APPARATUS, SYSTEMS, AND METHODS FOR THE FIXATION OR FUSION OF BONE

SI-Bone Inc., San Jose, ...

1. A method for the fixation or fusion of the sacroiliac joint, the method comprising:creating an insertion path through the ileum, across the sacroiliac joint, and into to the sacrum;
inserting a compressive implant having a longitudinal axis through the insertion path into the ileum, through the sacroiliac joint, and into the sacrum, the compressive implant comprising an anchor body having a distal end with an external screw thread and an elongated implant structure configured to be coaxially disposed over a proximal portion of the anchor body;
anchoring the distal end of the anchor body in an interior region of the sacrum before compressing the sacroiliac joint;
advancing the elongated implant structure coaxially over the proximal portion of the anchor body;
abutting a washer against an exterior surface of the ileum, the washer disposed coaxially over a proximal portion of the compressive implant; and
compressing the sacroiliac joint.

US Pat. No. 10,363,140

SYSTEMS, DEVICE, AND METHODS FOR JOINT FUSION

SI-Bone Inc., Santa Clar...

1. A system for the fusion of the sacroiliac joint, the system comprising:a guide pin configured to have a length greater than a mediolateral side to side width of an adult human patient's pelvis, the guide pin having a proximal end with a first alignment feature and a distal end with a second alignment feature;
a broach having a lumen for receiving the guide pin, the lumen having a complementary alignment feature that is configured to interact with the first alignment feature and the second alignment feature to register the broach with the guide pin in a predetermined orientation, the broach configured to form a rectilinear cavity in bone; and
an implant having a rectilinear cross-section transverse to a longitudinal axis of the implant, the implant configured to have a length greater than the width between a surface of the patient's right ilium and a surface of the patient's left ilium, the implant sized to fit through the cavity formed by the broach,
wherein the broach further comprises:
an elongate body with a proximal end, a distal end, at least three faces between the distal end and the proximal end, a plurality of apices formed at the junctions between adjacent faces, and a longitudinal axis, the lumen extending throughout the elongate body about the longitudinal axis, wherein the lumen is sized and shaped for receiving the guide pin;
a plurality of cutting surfaces spaced apart along the longitudinal axis of the elongate body and located on the distal end of the elongate body for shaping the cavity to receive the implant, wherein the plurality of cutting surfaces are oriented along the plurality of apices and become progressively smaller in size towards the distal end; and
a plurality of additional cutting surfaces aligned with the plurality of apices for cutting channels in the cavity to receive a bone graft material.

US Pat. No. 10,201,427

INTEGRATED IMPLANT

SI-Bone Inc., Santa Clar...

1. A method for fusing bone, comprising:identifying a bone site comprising a first bone segment, a second bone segment, and a joint between the first and second bone segments;
driving a first implant through the first bone segment using an axial, non-rotational force, wherein the first implant comprises a proximal end, a distal end, a longitudinal axis, and at least three planar wall portions that are arranged parallel to the longitudinal axis, wherein the distal end of the first implant comprises a plurality of cutting edges formed by the at least three planar wall portions;
driving the first implant transversely across the joint; and
driving the first implant into the second bone segment.

US Pat. No. 10,194,962

MATRIX IMPLANT

SI-Bone Inc., Santa Clar...

1. A modular implant for the fixation or fusion of the SI-Joint, the modular implant comprising:a distal portion comprising a distal guide pin receptacle;
a proximal portion comprising a proximal guide pin receptacle; and
at least one repeating internal portion comprising:
a plurality of apex struts joined together by oblique support struts arranged in an oblique configuration between the apex struts, and
a plurality of transverse support struts arranged perpendicularly to the apex struts, the plurality of transverse support struts arranged in a rectilinear configuration at both a proximal end and a distal end of the repeating internal portion;
wherein the at least one internal repeating portion is positioned between the distal portion and the proximal portion.

US Pat. No. 10,166,033

IMPLANTS FOR BONE FIXATION OR FUSION

SI-Bone Inc., Santa Clar...

1. A method of implanting a curved implant across a joint or fracture between a first bone segment and a second bone segment, the method comprising:forming a curved insertion path from the first bone segment, across the joint or fracture between the first bone segment and the second bone segment, and to the second bone segment, wherein the curved insertion path has a predetermined radius of curvature along its length;
inserting a curved guidewire along the curved insertion path;
disposing a drill bit over the curved guidewire;
drilling a curved bore along the curved guidewire;
disposing a broach over the curved guidewire;
shaping the curved bore with the broach to form the insertion path; and
inserting a curved implant having a matching radius of curvature into the curved insertion path and into the first bone segment, across the joint or fracture, and into the second bone segment.

US Pat. No. 10,376,206

NEUROMONITORING SYSTEMS AND METHODS FOR BONE FIXATION OR FUSION PROCEDURES

SI-Bone Inc., Santa Clar...

1. A method of inserting an implant into a patient, the method comprising:inserting a guide pin into the patient at a first site;
delivering a first electrical stimulus through the guide pin while the guide pin is inserted into the patient at the first site;
monitoring a second site for a first electrophysiological signal after the step of delivering the first electrical stimulus;
drilling a bore over the guide pin at the first site with a drill bit;
shaping the bore with a broach; and
inserting the implant into the bore.

US Pat. No. 10,426,533

FENESTRATED IMPLANT

SI-Bone Inc., Santa Clar...

1. An implant for bone fixation, the implant comprising:an elongate body having a longitudinal axis, a distal end, a proximal end, a rectilinear cross section transverse to the longitudinal axis having three or four sides, and a plurality of faces, each of the plurality of faces formed from a wall with a thickness between 1 mm and 5 mm in thickness, and each face having a width and a plurality of fenestrations, the plurality of fenestrations each having a diameter that is between about 0.2 to about 0.5 of the width of its associated face, the elongate body having a central lumen located along the longitudinal axis and configured to receive a guide pin, wherein each of the plurality of fenestrations reach and provide access to the central lumen, wherein a concentration or number of fenestrations is higher in a distal half of the elongate body than in a proximal half, wherein the distal end of the elongate body is tapered to facilitate implantation into the bone, and wherein the elongate body has a bending strength or a shear strength of at least 0.5 relative to a reference elongate body with identical dimensions and material composition but without any fenestrations.