US Pat. No. 9,060,847

OPTICAL HYDROGEL MATERIAL WITH PHOTOSENSITIZER AND METHOD FOR MODIFYING THE REFRACTIVE INDEX

University of Rochester, ...

1. An optical device comprising an optical, hydrogel polymeric material with irradiated regions that define refractive structures,
wherein the irradiated regions are characterized by a positive change in refractive index and exhibit little or no scattering
loss, and the optical, polymeric material comprises a photosensitizer to enhance the photoefficiency of two photon absorption
by the polymeric material to form the refractive structures, wherein the photosensitizer permits one to irradiate the regions
at a given average laser power using a scan rate that is at least fifty times greater than a scan rate without the photosensitizer
in the material, or at a given scan rate that permits one to set an average power of the laser to a value that is at least
two times less than an average laser power without the photosensitizer in the material, yet provide a similar positive change
in refractive index within the irradiated regions, and wherein the optical, hydrogel polymeric material further includes at
least three monomeric components: a first monomeric component is present in an amount of at least 60% by weight, and its homopolymer
will have a refractive index of at least 1.50; a second monomeric component is present in an amount from 3% to 20% by weight,
and a hydrophilic component present in an amount from 2% to 30% by weight.

US Pat. No. 9,905,008

AUTOMATED FUNDUS IMAGE FIELD DETECTION AND QUALITY ASSESSMENT

UNIVERSITY OF ROCHESTER, ...

1. A method for determining the sufficiency of a set of images for use in ocular screening, comprising:
identifying the eye and field position of each image from a plurality of ocular images comprising a selected area of the eye;
dividing each image into quadrants;
determining the quality of each quadrant;
evaluating the quadrants spanning the selected area to assign a comprehensive image quality metric for the selected area of
the eye; and

determining the sufficiency of the set of images based on the metric for rendering a medical diagnosis as to the presence
and extent of ocular disease.

US Pat. No. 9,076,570

NANO-COMPOSITE STRUCTURES, METHODS OF MAKING, AND USE THEREOF

Rochester Institute of Te...

1. A polymer-free nano-composite electrode comprising purified carbon nanotubes and germanium nanoparticles or purified carbon
nanotubes and silicon nanoparticles, wherein the nanoparticles are non-covalently incorporated into the nano-composite electrode
on exterior surfaces of the carbon nanotubes, such that the silicon nano-composite electrode comprises a reversible lithium
ion charge capacity exceeding 900 milliamp-hours per gram of electrode and the germanium nano-composite electrode comprises
a reversible lithium ion charge capacity exceeding 400 milliamp-hours per gram of electrode.

US Pat. No. 10,429,400

CHEMICAL ASSAY TO VERIFY THE QUANTITY AND QUALITY OF SESQUITERPENE LACTONE DERIVATIVES

South Dakota Board of Reg...

1. A method for authenticating a medication comprising:obtaining an antimalarial medication;
combining a reactive system and the antimalarial medication, wherein the reactive system comprises a solvent comprising ethyl lactate, and an acid, wherein the solvent has a Hildebrand solubility of less than 24 MPa1/2; and wherein the acid has a pKa of less than 4.75;
allowing the reactive system and the antimalarial medication to react for less than 30 minutes at a temperature of between about 20° C. to about 35° C.; wherein the solvent reacts with the antimalarial medication to produce a color change; and
identifying whether the antimalarial medication is counterfeit or efficacious based on the color change.

US Pat. No. 9,599,555

DOPING PROFILE MEASUREMENT USING TERAHERTZ TIME DOMAIN SPECTROSCOPY (THZ-TDS)

Rochester Institute of Te...

1. A system for determining a doping profile of a sample comprising:
a generator of terahertz light of multiple frequencies;
a first detector of terahertz light of multiple frequencies, wherein the generator and first detector are configured to operate
in a transmission or reflection mode with respect to independently exposing both a sample of unknown doping profile and an
undoped reference sample to terahertz frequency radiation traveling through the unknown sample and through the reference sample
and detecting a measured spectra of terahertz frequency for each of the unknown sample and the reference sample;

a materials refractive index library comprising a database comprising multiple doping concentrations of a dopant for a base
material and at each of the multiple doping concentrations a refractive index and absorption coefficient at each of different
wavelengths; and

a processor comprising an inverse algorithm that can match simulated spectra using a trial doping profile and the materials
library with the measured spectra from the sample, and map out or measure an activated doping profile into, or a free carrier
distribution into, the interior of the sample.

US Pat. No. 9,372,530

ASPECT-RATIO INDEPENDENT, MULTIMEDIA CAPTURE AND EDITING SYSTEMS AND METHODS THEREOF

Rochester Institute of Te...

1. A multimedia capture system comprising:
a plurality of imaging systems, each imaging system having an image sensor that receives image data sufficient to capture
portions of a scene from at least partially different locations; and

one or more detection systems, each detection system having a detection sensor that receives positioning data sufficient to
determine a relative position of each of the plurality of imaging systems with respect to the different locations of the scene
from where the image data is captured, wherein the relative position of each of the plurality of imaging systems and the captured
scene portions are used to generate a multimedia presentation of the scene and wherein the determination of a relative position
of each of the plurality of imaging systems is provided by the one or more detection systems wherein the detection sensor
of at least one of the one or more detection systems is not an image sensor of the particular imaging system itself.

US Pat. No. 9,642,709

ARTIFICIAL HIP JOINT REPLACEMENT SYSTEM

Cornell University, Itha...

1. An artificial hip joint replacement system comprising:
an acetabulum portion comprising:
a cup suitable to be received by a subject's acetabular bone, said cup comprising:
a rigid portion and
an elastic portion comprising an elongate finger or tab, a curved beam, or a short rod-like cylinder wherein the elastic portion
comprises a proximal end and a distal end, the elastic portion being attached to the rigid portion at some point other than
the distal end, wherein the distal end protrudes away from the rigid portion toward an interior region of the cup;

a ball, having a surface and a center, received by said cup and in contact with the distal end of the elastic portion, wherein
the rigid portion has an ellipsoidal shape and the ball has a spherical shape; and

a femoral stem attached to said ball, wherein the distal end of the elastic portion is positioned to allow a space between
said ball and the rigid portion of the cup and cause expansion of the space so the ball and the rigid portion of the cup are
further apart from one another during periods of low mechanical loads, and wherein the cup has a center and when the ball
and cup centers are coincident, the space between the surface of the ball and the rigid portion of the cup is not uniform.

US Pat. No. 9,339,224

EVENT DOSIMETER DEVICES AND METHODS THEREOF

Rochester Institute of Te...

1. A dosimetry device for use in an ambient environment, the device comprising:
a housing configured to be secured to at least one location on a person such that the person is wearing or carrying the housing
in the ambient environment;

at least one sensor at least partially disposed within the housing and accessible to the ambient environment, the at least
one sensor being configured to derive a plurality of parametric signals from either a) acceleration readings generated from
movement of the person, or b) pressure readings generated from perturbations propagating in the ambient environment, resulting
from an identified event;

at least one memory device disposed within the housing, the at least one memory device including a plurality of memory locations,
the plurality of memory locations being configured to store personal medical history data of the person that is wearing or
carrying the housing in the ambient environment, aggregate medical history data, and parametric data corresponding to the
plurality of parametric signals;

a control circuit disposed in the housing and coupled to the at least one sensor and the at least one memory device, the control
circuit being configured to tailor and adjust an individualized injury threshold for the person based on the personal medical
history data and the aggregate medical history data and store the tailored and adjusted individualized injury threshold prior
to the identified event, and the control circuit being further configured to provide in real time an injury risk assessment
corresponding to the identified event by determining whether one or more of the plurality of parametric signals exceeds the
stored individualized injury threshold for the person; and

at least one input/output (I/O) device coupled to the control circuit, the at least one I/O device being configured to provide
the injury risk assessment in response to an assessment analysis request, whereby medical treatment of the person is guided
according to the injury risk assessment that is provided by the I/O device, when the one or more of the plurality of parametric
signals exceeds the stored individualized injury threshold for the person.

US Pat. No. 9,310,825

STABLE VOLTAGE REFERENCE CIRCUITS WITH COMPENSATION FOR NON-NEGLIGIBLE INPUT CURRENT AND METHODS THEREOF

Rochester Institute of Te...

1. A voltage reference circuit comprising:
a bandgap circuit comprising,
a closed-loop differential operational amplifier, including a non-inverting input port, an inverting input port and an amplifier
output port, the non-inverting input port potential being substantially equal to the inverting input port potential, the differential
operational amplifier subject to field emission currents;

a first circuit comprising a first current mirror including a first gate coupled to the amplifier output port, the first gate
having an oxide layer sized to be subject to field emission currents, a first input port coupled to a voltage supply and a
first output port coupled to the inverting input port, the first circuit also including a first diode structure coupled between
the first output port and a ground potential, and

a second circuit comprising a second current mirror including a second gate coupled to the amplifier output port, the second
gate having an oxide layer sized to be subject to field emission currents, a second input port coupled to the voltage supply,
and a second output port coupled to the non-inverting input port, the second circuit also including a first resistor and a
second diode structure coupled in series between the second output port and the ground potential such that the first resistor
establishes a proportional-to-absolute temperature (PTAT) current characterized by a selected temperature coefficient;

a tuning network coupled to the to the non-inverting input port and the to the inverting input port, the tuning network being
configured to provide a complementary-to-absolute temperature (CTAT) current that substantially cancels the selected temperature
coefficient;

a third circuit comprising a third current mirror including a third gate coupled to the amplifier output port, the third gate
having an oxide layer sized to be subject to field emission currents, the third circuit including a third input port coupled
to the voltage supply, the third circuit also including a third output port coupled to the tuning network and a second resistor
disposed between the third output port and the ground potential, the second resistor coupled to a voltage reference port that
is biased such that the CTAT current and the PTAT current are combined to establish a substantially temperature independent
voltage reference signal across the second resistor; and

a closed-loop buffer amplifier including at least one buffer input coupled to the third output port and at least one buffer
output port, wherein the differential operational amplifier includes at least one operational amplifier input transistor and
the input port of the buffer amplifier includes at least one buffer input transistor, the size of the at least one operational
amplifier input transistor being substantially matched to the size of the at least one buffer input transistor to substantially
reduce the field emission currents propagating in the substantially temperature independent voltage reference signal.

US Pat. No. 9,729,994

SYSTEM AND METHOD FOR LISTENER CONTROLLED BEAMFORMING

University of South Flori...

1. A method to provide assistive listening for a plurality of listeners in an environment comprising a plurality of acoustics
sources, the method comprising:
receiving, at one or more microphone arrays located in an environment, an acoustic signal from each of a plurality of acoustic
sources located in the environment, wherein one or more of the plurality of acoustic sources are mobile acoustic sources;

transmitting the acoustic signal received from each of the plurality of acoustic sources located in the environment to an
acoustic beam forming processor;

determining, at the acoustic beamforming processor, a location of each of the plurality of acoustic sources in the environment;
transmitting, from the acoustic beamforming processor, the location of each of the plurality of acoustic sources in the environment
to one or more listener-controlled interface devices located in the environment, wherein each of the one or more listener-controlled
interface devices are located distant from the acoustic beamforming processor;

displaying the location of each of the plurality of acoustic sources in the environment on the one or more listener-controlled
interface devices;

selecting a target location of a mobile acoustic source from the locations displayed on the one or more listener-controlled
interface devices;

processing, at the acoustic beamforming processor, the acoustic signals from each of the plurality of acoustic sources to
generate a steered beam pattern focused at the target location of the mobile acoustic source selected on each of the one or
more listener-controlled interface devices;

transmitting, from the acoustic beamforming processor, the steered beam pattern to one or more of the listener-controlled
interface devices based upon the target location of the mobile acoustic source selected on the listener-controlled interface
device;

tracking, at the acoustic beamforming device, the movement of the target location of the mobile acoustic source using a an
acoustic tracking algorithm; and

adjusting, at the acoustic beamforming device, the steered beam pattern based upon the movement of the target location of
the mobile acoustic source.

US Pat. No. 9,138,172

METHOD FOR MONITORING EXPOSURE TO AN EVENT AND DEVICE THEREOF

Rochester Institute of Te...

1. A method for monitoring exposure of an individual to an event, the method comprising:
obtaining, by a dosimetry computing device comprising at least one pressure sensor, one or more sensor readings from the at
least one sensor;

identifying, by the dosimetry computing device, a blast event comprising a pressure shock front experienced by the individual
based on at least one of the one or more obtained sensor readings or one or more determinations based on the one or more obtained
sensor readings exceeding a defined trigger threshold value based on one or more selection criteria;

determining a direction of the propagation of the blast event pressure shock front experienced by the at least one sensor;
and

storing, by the dosimetry computing device, at least one of the one or more determinations or the one or more obtained sensor
readings which exceed one or more of the selection criteria when the blast event is identified.

US Pat. No. 9,840,782

ELECTROCHEMICAL PROCESS FOR PRODUCING GRAPHENE, GRAPHENE OXIDE, METAL COMPOSITES, AND COATED SUBSTRATES

ROCHESTER INSTITUTE OF TE...

1. An electrochemical process for producing graphene/graphene oxide comprising:
immersing in an electrolyte-free electrochemical bath, comprising water and an organic liquid, an anode electrode comprising
graphite and a cathode electrode comprising an electrically conductive material; and

applying an electrical potential between the anode and the cathode, sufficient to cause Joule heating and oxidation of the
water and cleavage of graphene by embrittlement from the graphite of the anode forming graphene/graphene oxide and at least
one of convective migration and electrical migration of the cleaved graphene in the bath.

US Pat. No. 9,668,689

EVENT DOSIMETER DEVICE AND METHODS THEREOF

Rochester Institute of Te...

1. A method comprising:
providing a device comprising a housing having at least one sensor in an ambient environment, the at least one sensor being
configured to derive a plurality of parametric signals from either a) acceleration readings generated from movement of the
person, or b) pressure readings generated from perturbations propagating in the ambient environment, resulting from an identified
event;

providing personal medical history data of a person that is wearing or carrying the device in the ambient environment, aggregate
medical history data, and parametric data, which parametric data corresponds to the plurality of parametric signals;

tailoring and adjusting an individualized injury threshold for the person based on the personal medical history data and the
aggregate medical history data;

storing the tailored and adjusted individualized injury threshold prior to the identified event;
providing in real time an injury risk assessment corresponding to the identified event by determining whether one or more
of the plurality of parametric signals exceeds the stored individualized injury threshold for the person;

providing human perceivable indicia corresponding to the injury risk assessment data in response to a user assessment analysis
request; and

guiding medical treatment of the person when the stored individualized injury threshold is exceeded.

US Pat. No. 9,833,174

METHOD FOR DETERMINING HEARING THRESHOLDS IN THE ABSENCE OF PURE-TONE TESTING

ROCHESTER INSTITUTE OF TE...

1. A method for determining hearing thresholds in the absence of pure-tone testing, comprising:
administering an adaptive speech recognition test to an individual, which comprises administering to the individual a plurality
of items from a calibrated item pool comprising items scaled along a continuum of speech recognition ability, each administered
item comprising two trials and each trial comprising a paired comparison of utterances, wherein the utterances can be the
same or different from one another and the difference comprises acoustic and phonetic features occurring within minimal pairs,
obtaining a response from the individual based on the individual's speech recognition ability to distinguish the acoustic
and phonetic features by a comparison of a first utterance of the paired utterances with a second utterance of the paired
utterances wherein at least one of the first and second utterances is a spoken utterance for the individual to hear, wherein
a relative difficulty of a subsequent item is determined by the correctness of the response to a previous item, assigning
a scoring value to the response from the individual for each administered item, obtaining a test score from a plurality of
response scoring values, and converting the test score to a scaled score representing speech recognition ability expressed
in the same metric as the item difficulty; and

calculating a hearing threshold, without the use of pure-tone testing, designated as yj for the individual at least at one of the following frequencies, wherein j =0.5, 1, 2, 4, and 8 kHz using the formula

yj=bj0+bj1x1+bj2x2+bj3x3
wherein the value for x1 expressed on a 0 to 100 scale is the test score of the administered adaptive speech recognition test,

the value for x2 is the chronological age of the individual expressed in years, and

the value for x3 is the self-report of perceived hearing handicap/impairment of 1 for yes and 0 for no, wherein

at j=0.5 kHz the bj0, bj1, bj2and bj3 constants are 103.69, ?1.23, ?0.21, and 7.55, respectively;

at j=1 kHz the bbj0, bbj1, bbj2, and bj3 constants are 133.27, ?1.59 , ?0.30, and 9.40, respectively;

at j=2 kHz the bjo, bj1, bj2, and bj3 constants are 154.00 , ?1.92 , ?0.17, and 7.51, respectively;

at j=4 kHz the bj0, bj1, bj2, and bj3 constants are 144.57 , ?1.84, 0.06, and11.10, respectively; and

at j=8 kHz the bj0, bj1, bj2, and bj3 constants are 122.91 , ?1.67, 0.38, and 13.57, respectively.

US Pat. No. 9,785,835

METHODS FOR ASSISTING WITH OBJECT RECOGNITION IN IMAGE SEQUENCES AND DEVICES THEREOF

ROCHESTER INSTITUTE OF TE...

1. An adaptive method for aiding a user in classifying objects from field of view images using eye fixation, the method comprising:
obtaining a sequence of fixation tracking images from an eye tracking video of one or both of an observer's eyes and a sequence
of field of view images from a view tracking video of what is in view of the observer, wherein the sequence of fixation tracking
images are synchronized in time with the sequence of field of view images;

determining by an object recognition processing apparatus when in the sequence of fixation tracking images an eye of the observer
fixates on a location in one or more images of the sequence of field of view images;

correlating by the object recognition processing apparatus the determined eye fixation to a location in the one or more images
of the sequence of field of view images;

extracting image data surrounding the fixated location from the one or more images of the sequence of field of view images;
presenting an operator of the object recognition processing apparatus with the extracted image data;
specifying a label for an object within the presented image data to classify the object by i) the operator assigning a label
to the object based upon the presented image data, ii) auto-accepting a label from labelled image data in a classification
database for the object representing the closest match to the presented image data, or iii) showing the operator a ranked
set of a plurality of labels from labelled image data in the classification database associated with the closest matches to
the presented image data, wherein the operator selects one of the plurality of labels as the label for the object;

adding to the classification database a record of the presented image data comprising the specified label; and
repeating the above determining, correlating, extracting, presenting, specifying and adding steps on a further unidentified
object from the extracted image data,

so as to build the classification database from the classified object and the further classified objects.

US Pat. No. 10,018,430

HEAT TRANSFER SYSTEM AND METHOD INCORPORATING TAPERED FLOW FIELD

ROCHESTER INSTITUTE OF TE...

1. A method for enhancing the flow boiling heat transfer performance of an apparatus, comprising:providing a heat transfer system comprising:
a fluid inlet;
a fluid outlet;
a substrate through which heat is transferred across, a portion of the substrate surface comprising a heat transfer region, which comprises a heat transfer surface having a plurality of enhancement features from about 1 micron to about 3 mm in height on the surface of the substrate; and
a flow field comprising an open region extending between the fluid inlet and fluid outlet and a fluidic region comprising the area between the enhancement features, the fluidic region in fluid communication with and adjacent to the open region, wherein in any cross-section of the heat transfer region fluid in the heat transfer region is in fluid communication with the open region and wherein the flow field cross-sectional area increases in the fluid flow direction by increasing the height normal to the substrate of the flow field and the open region;
flowing fluid in the fluid inlet through the flow field;
nucleating bubbles in the fluid within the heat transfer region, wherein a plurality of bubbles emerge into the open region and liquid refills the space vacated by the bubbles over the heat transfer surfaces causing the heat transfer surfaces to rewet;
flowing liquid and vapor out the fluid outlet in a manner to transfer heat through the substrate to the flow field which reduces the acceleration pressure drop as well as total pressure drop and enhances the critical heat flux and heat transfer coefficient during flow boiling.

US Pat. No. 10,598,861

METHOD AND SYSTEM TO PASSIVELY ALIGN AND ATTACH FIBER ARRAY TO LASER ARRAY OR OPTICAL WAVEGUIDE ARRAY

Indiana Integrated Circui...

1. A method comprising:(a) providing a first waveguide having a tapered end;
(b) providing a second waveguide having a tapered end;
(c) positioning the tapered ends of the first and second waveguide overlapping in spaced parallel or substantially parallel relation;
(d) providing an optical fiber positioned in optical alignment with an end of the second waveguide opposite the tapered end;
(e) propagating light toward the tapered end of the first waveguide producing evanescent light that is received by the tapered end of the second waveguide;
(f) propagating evanescent light received by the tapered end of the second waveguide through the second waveguide; and
(g) transferring the light propagating through the second waveguide to the optical fiber.

US Pat. No. 10,409,004

METHOD AND SYSTEM TO PASSIVELY ALIGN AND ATTACH FIBER ARRAY TO LASER ARRAY OR OPTICAL WAVEGUIDE ARRAY

Indiana Integrated Circui...

1. A system comprising:a first substrate having first and second ends, the first substrate including an optical fiber in a groove;
a second substrate having first and second ends, the second substrate including a first waveguide having first and second ends, wherein the first end of the second substrate is positioned proximate to the first end of first substrate; and
a third substrate having first and second ends, the third substrate including a second waveguide having first and second ends, wherein:
the second and third substrates are arranged with the first ends of the first and second waveguides overlapping in spaced parallel or substantially parallel relation; and
the first and second substrates are arranged with the second end of the second waveguide in optical alignment with an end face of the optical fiber.

US Pat. No. 10,292,594

METHOD AND SYSTEM FOR CONTACTLESS DETECTION OF CARDIAC ACTIVITY

ROCHESTER INSTITUTE OF TE...

1. A method for contactless detection of cardiac activity of a subject, comprising:monitoring blood volume pulse in real-time comprising detecting a first pulse resulting from a first contraction of the heart prior to the following contraction of the heart on a pulse by pulse basis through the skin of the subject with a contactless sensor by capturing with the sensor incident light reflected off the skin representing the pulse of the subject;
converting an optical signal of the reflected light to an electrical signal comprising a frequency;
feeding the captured electrical signal to a feedback control system;
locking and tracking over time the frequency of the captured electrical signal within a range corresponding to an expected range of heart rate using the feedback control system;
measuring the frequency of the electrical signal at the output of the feedback control system;
extracting the pulse rate in real-time on a pulse by pulse basis from the measured frequency of the electrical signal at the output of the feedback control system;
tracking the pulse rate to detect pulse by pulse variability of the subject's heart rate in real-time; and
analyzing the tracked heart rate variability in real-time on a beat by beat basis to determine a physiological condition of the subject.

US Pat. No. 10,393,643

OPTICAL VORTEX CORONAGRAPH SCATTEROMETER

Rochester Institute of Te...

1. An optical vortex coronagraph scatterometer comprising:a light source of wavelength ?;
a detector;
a scattering cell in optical communication with the light source;
a circular aperture having a radius R at a distance d from the scattering cell in optical communication with the light source;
a pivot point between the circular aperture and the scattering cell allowing relative movement of the light source and the scattering cell with respect to the circular aperture;
an optical vortex element;
a first lens comprising a focal length f1 disposed between the circular aperture and the optical vortex element at a distance of f1 from the circular aperture and a distance of f1 from the optical vortex element; and
a second lens comprising a focal length f2 disposed between the optical vortex element and the detector at a distance of f2 from the detector and a distance of f2 from the optical vortex element, wherein the optical vortex element is disposed between the circular aperture and the detector.

US Pat. No. 10,085,690

SYSTEM AND METHOD FOR FEEDBACK OF DYNAMICALLY WEIGHTED VALUES

Rochester Institute of Te...

1. A method comprising:monitoring, by a sensor, a signal from each of at least two functions to record a set of values for each signal monitored;
determining, by a processing device, for each signal monitored the value of the signal relative to a desired goal being monitored over time;
identifying, by a processing device, each monitored signal exhibiting a relative value representing a change in a pre-identified direction and each monitored signal exhibiting a relative value not representing a change in the pre-identified direction, wherein each identified signal is aligned in the same direction relative to the pre-identified direction;
dynamically weighting, by a processing device, each of the aligned signals based upon the determined value relative to the desired goal of each of the aligned signals;
summing, by a processing device, the dynamically weighted signals to a finite total value;
adjusting, by a processing device, each dynamically weighted signal based upon the performance of each of the aligned signals relative to each other over time while maintaining the finite total value;
displaying over time the dynamically weighted signals as an aggregate; and
causing a desired change in at least one monitored function based upon feedback of the displayed aggregate signals.

US Pat. No. 10,086,336

ULTRA-THIN NANOMETER SCALE POLYMERIC MEMBRANES

Rochester Institute of Te...

1. A process for producing an ultra-thin nanometer-scale polymeric membrane comprising:forming a polymer film on a first side of a nanoporous substrate;
swelling the polymer film on the first side of the nanoporous substrate by applying a solvent on a second side of the nanoporous substrate opposite the first side which migrates through the nanoporous substrate to the first side; and
evaporating the solvent from the second side of the nanoporous substrate while limiting evaporation of the solvent from the first side of the nanoporous substrate.

US Pat. No. 10,292,445

EVENT MONITORING DOSIMETRY APPARATUSES AND METHODS THEREOF

ROCHESTER INSTITUTE OF TE...

1. A multiple use dosimetry apparatus comprising:a pressure sensor capable of detecting a blast pressure waveform disposed in a housing;
a cover configured to permit blast compression waves to pass through, the cover which extends out and away from the housing is seated over the pressure sensor and comprises a mesh structure comprising a particle filtering mesh layer configured to exclude dust seated against a structural mesh layer configured to provide structural integrity to the particle filtering mesh layer, wherein the structural mesh layer comprises larger mesh openings than the mesh openings of the particle filtering mesh layer in a manner that protects the pressure sensor and the particle filtering mesh layer from physical damage; and
a dosimetry processing device with a memory coupled to the pressure sensor in the housing, the dosimetry processing device configured to execute programmed instructions stored in the memory comprising obtaining readings from the pressure sensor, storing the readings when obtained, conducting an analysis based on the obtained readings and outputting at least one of the stored readings or the conducted analysis, wherein the pressure sensor combined with the cover provides multi-directional sensitivity to blast direction and will detect the same pressure waveform independent of the relative orientation of the pressure sensor to the pressure front of the explosive blast to within fifty percent of the pressure waveform amplitude.

US Pat. No. 10,236,659

MODE-LOCKED LASERS ON SILICON BY PALLADIUM BONDING AND METHODS THEREFOR

Rochester Institute of Te...

1. A method for fabricating a mode-locked laser on a silicon substrate comprising:coating a palladium bonding layer on a silicon substrate;
bonding a mode-locked laser comprising an etch stop layer and compound semiconductor substrate to the palladium layer by a low temperature metal-mediated bonding technique;
removing the compound semiconductor substrate;
removing the etch stop layer; and
fabricating the mode-locked laser on the silicon substrate.

US Pat. No. 10,193,354

NEAR ZERO VOLT STORAGE TOLERANT ELECTROCHEMICAL CELLS THROUGH REVERSIBLE ION MANAGEMENT

Rochester Institute of Te...

1. An electrochemical cell, comprising:a positive electrode;
a negative electrode; and
an electrolyte, wherein the electrochemical cell contains reversible ions in an amount sufficient to maintain a negative electrode potential verses reference level that is less than a damage potential of the negative electrode and a positive electrode potential verses reference level that is greater than a damage potential of the positive electrode of the cell under an applied load at a near zero cell voltage state, such that the cell is capable of recharge from the near zero cell voltage state.

US Pat. No. 10,473,410

POOL BOILING ENHANCEMENT WITH FEEDER CHANNELS SUPPLYING LIQUID TO NUCLEATING REGIONS

Rochester Institute of Te...

1. A boiling heat transfer unit comprising a substrate having a heat exchange region comprising a plurality of nucleating regions, each having a channel length and intersecting with open feeder channels having a length along the substrate surface, wherein the intersecting nucleating regions are disposed in a manner at the ends of the length of the feeder channels at a distance whereby vapor formed in the nucleating regions is moved away from the nucleating regions influencing liquid flow through the length of the feeder channels towards the nucleating regions suppressing nucleation along the length of the feeder channels and establishing continuous self-sustaining spatial ordering of separate vapor and liquid pathways increasing heat transfer due to developing region heat transfer in the feeder channels and enhancing overall boiling performance.

US Pat. No. 10,191,194

SPECTRAL TARGET FOR MACROSCOPIC AND MICROSCOPIC REFLECTANCE IMAGING

Rochester Institute of Te...

1. A spectral target for determining the spectral reflectance factor and/or colorimetric coordinates of a sample, comprising:a mirror-like substrate containing a plurality of microstructures arranged in an array across the surface of the substrate and each one of the plurality of microstructures having an opaque multi-layer spectrally selective coating with a specific spectral reflectance profile, wherein the substrate has multiple spectral selectivity profiles in multiple locations.

US Pat. No. 10,697,629

DEVICES WITH AN ENHANCED BOILING SURFACE WITH FEATURES DIRECTING BUBBLE AND LIQUID FLOW AND METHODS THEREOF

ROCHESTER INSTITUTE OF TE...

1. A boiling apparatus comprising:a substrate comprising a base comprising a first side and a second side, a heat generation region contacting surface on the first substrate side and a liquid contacting surface on the second substrate side, the liquid contacting surface comprising a sidewall heat transfer surface extending out from the substrate base and a bubble pathway heat transfer surface extending away from the base of the sidewall, wherein the sidewall heat transfer surface and the bubble pathway heat transfer surface intersect to form a single corner along the length of the intersection, the corner comprising a nucleation site comprising a plurality of nucleation cavities capable of forming bubbles in liquid in contact with the liquid contacting surface, the sidewall heat transfer surface and the bubble pathway heat transfer surface forming a liquid boiling cavity in communication with a bulk liquid, wherein heat from the heat generation region applied to the first substrate side is transferred to the second substrate side and boils liquid from the bulk liquid in the liquid boiling cavity by the formation of bubbles at the nucleation site causing the bubbles to depart from the nucleation site traversing a bubble pathway along the bubble pathway heat transfer surface away from the sidewall heat transfer surface wherein the bubble pathway heat transfer surface is sloped away from the sidewall heat transfer surface and extending to an end surface parallel to the substrate base to sweep the bubbles over the bubble pathway heat transfer surface enhancing heat transfer from the bubble pathway heat transfer surface and facilitating flow of the liquid from the bulk liquid in a direction perpendicular to the length of the intersection traversing a liquid pathway along the sidewall heat transfer surface towards the nucleation site enhancing heat transfer from the sidewall heat transfer surface, wherein the bubble pathway along the bubble pathway heat transfer surface and the liquid pathway along the sidewall heat transfer surface are separate non-interfering pathways intersecting at the corner creating a flow of the bubbles departing from the nucleation cavities wherein any bubbles formed along the bubble pathway heat transfer surface will be swept by the departing flow of the bubbles along the bubble pathway and the flow of bubbles does not interfere with the flow of liquid from the bulk liquid along the liquid pathway of the sidewall heat transfer surface toward the nucleation cavities, wherein the bubble pathway heat transfer surface originates at the single corner along the intersection of the sidewall heat transfer surface and the bubble pathway heat transfer surface, continuously extends away from the sidewall heat transfer surface and terminates at the end surface prior to a second corner being formed with another sidewall such that the overall heat transfer performance of the apparatus results in an enhancement in critical heat flux and heat transfer coefficient.

US Pat. No. 10,581,176

THIN-FILM SENSOR ANTENNA

Rochester Institute of Te...

1. A sensor antenna comprising:a thin film material constructed in the shape of an antenna having a response, the material comprising a designed sheet resistance capable of being modified by an external stimulus where the modified designed sheet resistance alters the antenna response to electromagnetic radiation.

US Pat. No. 10,292,658

APPARATUS, SYSTEM AND METHOD FOR MEDICAL ANALYSES OF SEATED INDIVIDUAL

Rochester Institute of Te...

1. An automated method for medical analysis of a seated individual comprising:placing an individual in a sitting position on a seat comprising at least one force sensor capable of measuring changes in the apparent weight of the seated individual;
collecting BCG data over at least a portion of the cardiac cycle;
determining a posture of the seated individual, the posture comprising an angle between the seat platform and the torso of the seated individual;
transforming the collected BCG data from a leaning forward BCG waveform to an upright BCG waveform based on the determined posture of the seated individual or extracting at least one posture-dependent feature from the collected BCG data; and
calculating the timing of the aortic valve opening based on one or more features of the transformed or extracted BCG data of the seated individual.

US Pat. No. 10,907,265

FLOW-REGULATED GROWTH OF NANOTUBES

Rochester Institute of Te...

1. A method for growing nanotubes via flow-regulated electrochemical anodization, comprising:flowing in a laminar flow an electrolyte between a metal anode and metal cathode within a channel up to 500 microns wide, wherein the distance between the anode and cathode is from 150 microns to 2050 microns;
providing an electrical current across the anode and cathode sufficient to cause electrochemical anodization growth of nanotubes on a surface of the anode; and controlling a rate of the laminar flow to effect a desired growth of the nanotubes in a laminar flow region, wherein the laminar flow comprises a flow rate having a Peclet number of above 100 sufficient to inhibit growth of an oxide layer on the nanotubes.

US Pat. No. 10,869,722

METHOD AND FIXTURE FOR GUIDED PEDICLE SCREW PLACEMENT

Rochester Institute of Te...

1. A method for spinal fixation comprising:scanning an affected segment of the spine of a patient in need of spinal fixation to generate image data;
generating a 3D model of the spine from the image data;
selecting a set of screw paths in the 3D model for attachment of an implant to the affected segment of the spine;
generating a 3D digital template of a combination screw guide fixture and implant comprising screw guides corresponding to the set of selected screw paths and at least one self-alignment bar comprising a vertebra mating surface;
making the combination screw guide fixture and implant from the 3D digital template by additive manufacturing;
locating the combination screw guide fixture and implant on the affected segment of the spine aligning the screw guides with the set of selected screw paths and contacting the at least one self-alignment bar vertebra mating surface with the vertebra;
drilling a hole in the vertebra corresponding to each screw path in the set of selected screw paths using the screw guides;
placing a surgical screw through each screw guide into the corresponding hole in the vertebra; and
tightening each surgical screw until the combination screw guide fixture and implant is tightly seated to the vertebra.

US Pat. No. 11,032,826

RADIO SPECTRUM SHARING LEVERAGING LINK ADAPTATION IN PRIMARY NETWORK

Rochester Institute of Te...

1. A wireless communication system, comprising:a plurality of wireless networks simultaneously operating over a same RF spectrum band, at least one network of the plurality of wireless networks comprising a secondary network having at least one radio frequency (RF) transmitting node, wherein each of the at least one radio frequency (RF) transmitting nodes is capable of estimating a change in the average throughput of a transmission of the at least one radio frequency (RF) transmitting node on at least one primary network of the plurality of wireless networks, wherein each at least one radio frequency (RF) transmitting node comprises:
a modulation classifier that estimates from a sensed wireless signal, a modulation scheme used in a transmission of a wireless signal that carries information over a wireless link that has been established in the at least one primary network of the plurality of wireless networks; and
a throughput estimator which determines, without exchanging information between networks of the plurality of wireless networks, a forward error control (FEC) channel coding rate for the sensed wireless signal, wherein the at least one radio frequency (RF) transmitting node in the secondary network uses information from the throughput estimator to determine a transmitting power level of the transmission of the at least one radio frequency (RF) transmitting node that does not reduce the throughput over the wireless link associated with the sensed wireless signal sent and received in the primary network by more than a prescribed target maximum value.
US Pat. No. 10,610,608

MODULAR IMAGING AGENTS CONTAINING AMINO ACIDS AND PEPTIDES

Rochester Institute of Te...

1. A process for synthesizing a targeted imaging agent comprising:providing an amino acid or amino amide that does not comprise a protected side chain and that comprises a) a protected, activated, or free acid, b) a protected or free amine, or c) both a) and b);
attaching a chelated metal or coupling a dye to the unprotected side chain of the amino acid or amino amide—prior to coupling to another amino acid, peptide, or targeting group—to form an amino acid or amino amide imaging agent; and then
coupling a targeting group comprising a free amine, thiol, or free acid to the amino acid or amino amide imaging agent at the a) protected, activated, or free acid, b) protected or free amine, or c) both a) and b) of the amino acid or amino acid, to form the targeted imaging agent.

US Pat. No. 10,905,339

OPPORTUNISTIC PLETHYSMOGRAPHY USING VIDEO CAMERAS

Rochester Institute of Te...

1. A method for capturing high-quality cardiac plethysmography signals automatically and seamlessly, comprising:providing a personal electronic device containing a video camera embedded therein and a computer program running in the background that periodically takes a picture of the person using the device with automated video capture functions on, runs at least one of a face detection and face recognition algorithm, and upon detection of a face freezes the automated video capture functions upon stabilization of the automated video capture functions, records a video with the automated video capture functions off, and then processes the video using algorithms which assess video quality by extracting video quality parameters;
processing the recorded video further when the video quality parameters are above predefined thresholds, to generate a plethysmography signal indicative of cardiac activity; and
optionally, processing the plethysmography signal to deduce cardiac activity, wherein the method maintains a pleasurable user experience with the personal electronic device.

US Pat. No. 10,890,377

VOLCANO-SHAPED ENHANCEMENT FEATURES FOR ENHANCED POOL BOILING

Rochester Institute of Te...

3. A method for enhancing pool boiling, comprising:heating a substrate having at least one volcano-shaped structure comprising a base, side and top enclosing a contained volume, the at least one volcano-shaped structure having at least one bottom opening and at least one top opening, wherein a cross-sectional area at the base is greater than a cross-sectional area at the top, the at least one volcano-shaped structure base adjacent to a surface of the substrate;
and covering the at least one volcano-shaped structure and the substrate with a liquid, such that vapor and entrained liquid flows in a predominantly continuous manner through either one of the at least one top opening and at least one bottom opening from inside the contained volume to outside the contained volume and liquid flows in a predominantly continuous manner through the other one of the at least one top opening and at least one bottom opening from outside the contained volume into the contained volume, with the vapor exiting from within the contained volume not interfering with the incoming liquid and enhancing at least one of a heat transfer coefficient and a critical heat flux on the substrate.

US Pat. No. 10,524,699

METHOD AND SYSTEM FOR MONITORING TERRAIN AND GAIT AND PREDICTING UPCOMING TERRAIN

ROCHESTER INSTITUTE OF TE...

1. A method for monitoring terrain and gait of a subject traversing terrain, the method comprising:characterizing a gait pattern of the subject traversing a plurality of terrain types for each of the plurality of terrain types traversed by:
receiving by a management computing device a first terrain data from a first proximity sensor on a first appendage of the subject, comprising determining a distance between the first proximity sensor and a surface of an approaching terrain throughout a gait cycle of the subject while traversing each of the plurality of terrain types and receiving by the management computing device a first gait speed data relating to the gait of the subject from a first gait sensor on a second appendage of the subject throughout the gait cycle of the subject while traversing each of the plurality of terrain types to establish a periodic terrain model normalized by gait period by applying a periodic function to the first terrain data establishing gait speed as an independent variable to the periodic terrain model specific to the subject for each of the plurality of terrain types traversed, wherein the first and second appendages can be the same or different appendages;
monitoring the gait pattern of the subject traversing a second terrain by receiving by the management computing device a second terrain data from the first proximity sensor and a second gait speed data from a second gait sensor to scale in time the periodic terrain model normalized by gait period to the incoming second gait speed data to identify the second terrain being traversed from established periodic terrain models;
predicting an upcoming terrain by the management computing device from the received second gait speed data and the second terrain data for the subject; and
providing a signal to the subject or a device worn by the subject based on the predicted upcoming terrain.

US Pat. No. 11,035,498

CAPSULE, IN-LINE MAGNETIC VALVE SYSTEM AND METHOD

Rochester Institute of Te...

1. A capsule comprising:a flexible outer shell comprising an inlet side and an outlet side capable of transforming into an asymmetric shape where the asymmetry is from the inlet side to the outlet side, wherein the flexible outer shell inlet side is free to move in response to a fluid flow; and
an internal medium encapsulated by the outer shell, the medium comprising a plurality of magnetic particles, wherein the plurality of magnetic particles are capable of moving in an applied external magnetic field to transform the outer shell.
US Pat. No. 11,038,181

FUEL CELLS WITH A NON-PARALLEL GAS FLOW CHANNEL CONFIGURATION AND METHODS THEREOF

ROCHESTER INSTITUTE OF TE...

1. A fuel cell apparatus comprising:at least one fuel cell comprising a proton exchange membrane electrode assembly between an anode plate and a cathode plate, the proton exchange membrane electrode assembly comprises an anode-side gas diffusion layer, anode catalyst layer, cathode-side gas diffusion layer, cathode catalyst layer and membrane, wherein the anode catalyst layer is disposed between the anode-side gas diffusion layer and the membrane and wherein the cathode catalyst layer is disposed between the cathode-side gas diffusion layer and the membrane;
the anode plate comprising a first set of a plurality of adjacent individual open gas flow channels embedded in the anode plate open to and adjacent the anode-side gas diffusion layer, each individual channel of the first set of a plurality of adjacent individual open gas flow channels extending between an input opening connected to a first anode manifold and an output opening connected to a second anode manifold; and
the cathode plate comprising a second set of a plurality of adjacent individual open gas flow channels embedded in the cathode plate open to and adjacent the cathode-side gas diffusion layer, each individual channel of the second set of a plurality of adjacent individual open gas flow channels extending between an input opening connected to a first cathode manifold and an output opening connected to a second cathode manifold; wherein
the first set of a plurality of adjacent individual open gas flow channels is spaced from and extends across a width of each individual channel of the second set of a plurality of adjacent individual open gas flow channels in a non-parallel configuration along their entire length and at least one individual gas flow channel in the first set of a plurality of adjacent individual open gas flow channels is disposed in a downward inclination to gravity along its entire length extending along the anode-side gas diffusion layer and at least one individual gas flow channel in the second set of a plurality of adjacent individual open gas flow channels is disposed in a downward inclination to gravity along its entire length extending along the cathode-side gas diffusion layer.

US Pat. No. 11,020,524

PERISTALTIC MICROPUMPS AND FLUID DELIVERY DEVICES THAT INCORPORATE THEM

University of South Flori...

1. A peristaltic micropump comprising:a substrate having a first side and a second side;
a microtube that extends across the first side of the substrate;
multiple pump actuators formed on the first side of the substrate and positioned adjacent to the microtube at discrete, spaced positions along the length of the microtube, each pump actuator comprising a solid actuation member that is configured to expand when actuated;
wherein the micropump is configured to sequentially actuate the pump actuators so as to cause their actuation members to sequentially expand and sequentially compress the microtube to create peristaltic action that drives fluid contained in the microtube along the length of the microtube; and
one or more electrical contacts located on a surface of the substrate, the one or more electrical contacts used to supply power to the micropump.

US Pat. No. 11,012,559

METHOD AND SYSTEM TO ENHANCE COMMUNICATION BETWEEN MULTIPLE PARTIES

Rochester Institute of Te...

1. A method for enhancing communication between multiple parties, comprising:initiating by a first user a communication connection between an initiating device and a receiving device of a second user, wherein the initiating and receiving devices are checked for accessible features;
wherein the initiating communication device comprises a profile of the first user containing a plurality of settings, each setting of the plurality associated with a different universal communication providing specific functions of data routed from the first user to a server associated with a service provider for each setting and wherein the receiving communication device comprises a profile of the second user containing a plurality of settings, each setting of the plurality associated with a different universal communication attribute providing specific functions of data routed from the first user to a server associated with a service provider for each setting,
choosing by the first user an attribute;
choosing by the first user the service provider from a plurality of service providers through which the at least one communication attribute is provided;
choosing by the second user an attribute,
choosing by the second user the service provider from a plurality of service providers through which the attribute is provided; and
utilizing by a network one or more of the enabled communication attributes of at least one of the first and second user to complete the communication connection between the initiating and receiving communication devices, wherein selected communication attributes are passed on to a signaling server and certain profile data is passed on to the second user.
US Pat. No. 10,927,132

TRANSMETALATION METHODS FOR THE SYNTHESIS OF PET AND SPECT IMAGING AGENTS

Rochester Institute of Te...

1. A process for the preparation of a radionuclide imaging agent, comprising:providing an imaging agent comprising a chelated place-holder metal from Row 5 or 6 of the Periodic Table of Elements;
loading the imaging agent onto a stationary phase stable to an acidic solution comprising a dilute aqueous solution of strong acid, pKaabout 2 and binding the loaded imaging agent onto the stationary phase;
reacting the chelated place-holder metal by flowing an acidic solution comprising a dilute aqueous solution of strong acid, pKaabout 2 and binding a replacement radioactive metal to the stationary phase bound imaging agent so as to replace the chelated place-holder metal of the imaging agent loaded on the stationary phase with the replacement radioactive metal; and
eluting the imaging agent comprising the chelated replacement radioactive metal from the stationary phase to provide a radionuclide imaging agent suitable for positron emission tomography or single-photon emission computed tomography.
US Pat. No. 10,875,979

FORMATION AND PROPERTIES OF CELLULAR FOAM FIBROUS MATERIAL

Rochester Institute of Te...

1. A foaming process for converting fibrous material into a cellular foam structure, comprising:mixing fibrous material and a solvent-based binding agent to form a mixture;
saturating the mixture with a pressurized gas to form a pressurized gas-saturated mixture;
reducing the pressure of the pressurized gas-saturated mixture to form a first stage expanded mixture with voids in the mixture; and
forming a second stage expanded mixture by boiling the solvent from the solvent-based binding agent to set the fibrous material and drive off the solvent to form a stable cellular foam structure having cushioning properties.

US Pat. No. 10,786,184

METHOD FOR DETERMINING HEARING THRESHOLDS IN THE ABSENCE OF PURE-TONE TESTING

Rochester Institute of Te...

1. A method for determining hearing thresholds of an individual in the absence of pure-tone testing, comprising:developing a pool of items comprising a plurality of items, each item comprising two trials and each trial comprising a paired comparison of utterances, wherein the utterances can be the same or different from one another and a difference comprises acoustic and phonetic features occurring within minimal pairs;
administering each item from the plurality of items to a first group of individuals having hearing loss to obtain a response to each of the items;
subjecting the responses to a scaling analysis to assign a difficulty value (di) and an associated standard error (se) to each of the items to create a calibrated item pool comprising items scaled along a continuum of speech recognition ability;
administering an adaptive speech recognition test comprising items from the calibrated item pool to an individual having hearing loss to obtain a response to the calibrated items based upon the individual's speech recognition ability;
calculating a test score for the individual based upon the responses to the calibrated items; and
applying multiple regression statistical methods to the test score of the individual together with variables comprising the individual's age and perception of hearing handicap to develop an equation converting the individual's adaptive speech recognition test score to hearing threshold values at several frequencies.