US Pat. No. 9,333,294

INSERTION DEVICE

MEDTRONIC MINIMED, INC., ...

1. A method for covering an insertion needle, comprising:
inserting a cannula into the skin of a patient with an insertion device, wherein the insertion device includes:
a hub removably attachable to a base of a cannula housing of an infusion set, said hub including a handle part and a guard
part, wherein said handle part has a vertical portion and a horizontal portion; and

a needle attached to the hub, wherein, for the entirety of its travel, the guard part is configured to slide along an outer
surface of the handle part according to a direction pulled to cover the needle, said direction being parallel to the needle's
longitudinal axis and perpendicular to the handle part's horizontal portion;

removing the insertion device from the cannula housing; and
sliding the guard part along the handle part in said direction parallel to the needle's longitudinal axis and perpendicular
to the handle part's horizontal portion so as to cover the needle with the guard part.

US Pat. No. 9,107,994

SYSTEMS FOR FLUID RESERVOIR RETENTION

Medtronic MiniMed, Inc., ...

1. A fluid infusion device, comprising:
a fluid reservoir having a first portion and a second portion; and
a housing defining a receiving portion for removably receiving the fluid reservoir within the housing, the housing having
a first side adjacent to a second side, the first side including a first engagement system that cooperates with the first
portion and the second side including a second engagement system that cooperates with the second portion, the first engagement
system including a wedge and a pin, the pin fixedly coupled to the first side of the housing and the wedge movable along the
pin between a first position and a second position to bias the fluid reservoir relative to the housing in a direction substantially
opposite a direction of fluid flow out of the fluid reservoir.

US Pat. No. 9,072,476

FLEXIBLE SENSOR APPARATUS

MEDTRONIC MINIMED, INC., ...

1. A sensor apparatus comprising:
a flexible analyte sensor; and
a flexible mounting base to carry the flexible analyte sensor including:
a flexible adhesive layer to removably attach to a skin surface;
a housing disposed on the adhesive layer to receive the flexible analyte sensor, said housing including a base layer and a
plurality of sidewalls depending from said base layer; and

a one-piece outer flexible layer that is entirely separate from the housing and from the flexible adhesive layer, wherein,
once assembled, the flexible adhesive layer and the outer flexible layer enclose therebetween the entirety of the housing,
including said plurality of sidewalls.

US Pat. No. 9,056,162

INSERTION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An insertion set, comprising:
a cannula housing of an infusion set including a cannula adapted to be inserted into the skin of a patient; and
an insertion device including:
a hub removably attachable to a base of the cannula housing of the infusion set, including a handle part and a guard part;
a needle attached to the hub; and
a collapse part attached to the handle part and having two opposing and parallel collapsible walls that are biased to improve
collapse of both walls when pressure is applied to the collapse part.

US Pat. No. 9,320,471

ALGORITHM SENSOR AUGMENTED BOLUS ESTIMATOR FOR SEMI-CLOSED LOOP INFUSION SYSTEM

Medtronic MiniMed, Inc., ...

1. An infusion system for infusing a fluid into the body of a patient, the system comprising:
a sensor system that includes a sensor for monitoring blood glucose concentration of a patient, and produces at least one
sensor signal, which is representative of the blood glucose concentration of the patient, and wherein the at least one sensor
signal is used to generate at least one sensor signal input;

a controller, wherein the controller uses the at least one sensor signal input and a derivative predicted algorithm to determine
at least one sensor-derived blood glucose trend, and wherein the at least one sensor-derived blood glucose trend is used to
determine blood glucose levels at a predetermined time in the future, wherein the derivative predicted algorithm calculates
a first derivative of a sensor current sample from the at least one sensor signal input at time period n, and then calculates
a first derivative of a sensor glucose value from the at least one sensor signal input using the first derivative of the sensor
current sample to determine future blood glucose levels, wherein the first derivative of the sensor current sample is calculated
from a slope of the sensor current sample versus time using a Savitzky-Golay finite impulse response filter; and

a delivery system that infuses a fluid into the patient, wherein operation of the delivery system is affected by commands
from the controller and the patient,

wherein the controller suspends fluid delivery if the at least one sensor-derived trend yields at least one blood glucose
level reading that is below a predefined low shutoff threshold.

US Pat. No. 9,143,941

SECURE COMMUNICATION BY USER SELECTABLE COMMUNICATION RANGE

MEDTRONIC MINIMED, INC., ...

1. An infusion system to administer fluid, the infusion system comprising:
an infusion pump having a pump processor, a pump memory and a pump radio to enable bi-directional communication, the pump
radio further including an attenuator being configurable and the pump memory storing a plurality of security modes, each of
the plurality of security modes configuring the attenuator to receive signals of a predetermined strength, and

a controller having a controller processor, a controller memory, a controller radio to transmit and receive communication
from the pump radio, the controller further having a graphical user interface shown on a display, and controls to manipulate
the graphical user interface, the controller being paired with the infusion pump based on pairing data,

wherein a security check is performed when the infusion pump receives a suspect signal, the suspect signal not matching the
predetermined strength associated with a selected security mode.

US Pat. No. 9,107,999

METHODS AND APPARATUSES FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP

MEDTRONIC MINIMED, INC., ...

1. A method of detecting an occlusion in an infusion pump having a reservoir and a drive mechanism that includes a motor and
one or more drive train components for infusing fluid from the reservoir into a body of a user through delivery of one or
more separate pulses of infusion fluid, wherein consecutive pulses of infusion fluid are separated by a period of time during
which no fluid is infused into the user's body, the method comprising:
during delivery of a single one of said one or more separate pulses of infusion fluid, periodically measuring the value of
a parameter associated with the motor or one of the drive train components to obtain a series of measurements;

determining a peak value of the series of measurements;
selecting a second value within the series of measurements later in time than the peak value;
calculating a difference between the peak value and the second value; and
declaring an occlusion has occurred if the difference exceeds a threshold value.

US Pat. No. 9,326,708

AMBIENT TEMPERATURE SENSOR SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A monitoring system for measuring a physiological parameter, the system comprising:
a housing having electronics, the electronics including heat-generating electronics, a first sensor and a second sensor;
the first sensor configured to measure a sensed amount of a physiological parameter and to generate a first signal based on
the sensed amount of the physiological parameter measured by the first sensor; and

the second sensor electrically connected to the electronics in the housing and configured to measure a temperature and to
generate a second signal based on the temperature measured by the second sensor;

the heat-generating electronics comprising a processor configured to determine an overall amount of the physiological parameter
based on the first signal generated from the first sensor and the second signal generated from the second sensor;

the second sensor held by a support structure, the second sensor thermally insulated from the heat-generating electronics
and the first sensor and the second sensor are non-abutting; and

a thermal insulation material arranged to thermally insulate the second sensor from the heat-generating electronics and the
first sensor, while the second sensor remains electrically connected to the heat-generating electronics in the housing, wherein
the thermal insulation material is configured to thermally insulate the second sensor so that the temperature measured by
the second sensor is thermally insulated from heat emitted by the first sensor, and the thermal insulation material is arranged
between the first sensor and the second sensor through all direct line-of-sight convection paths from the first sensor to
the second sensor such that the temperature measured by the second sensor is isolated from the heat emitted by the first sensor
through all direct line-of-sight convection paths.

US Pat. No. 9,330,237

PATTERN RECOGNITION AND FILTERING IN A THERAPY MANAGEMENT SYSTEM

Medtronic MiniMed, Inc., ...

1. A method of diabetes analysis, comprising:
receiving, using a processor and a glucose sensor, a plurality of glucose level readings over a plurality of days for a user,
each of the plurality of glucose level readings having multiple glucose level measurements for one of the plurality of days;

determining, using the processor, a common event occurrence in at least two of the glucose level readings;
analyzing, using the processor, the at least two glucose level readings from the common event occurrence onwards in time for
a time period;

identifying, using the processor, a glucose level pattern formed by the at least two glucose level readings having a similar
shape;

analyzing, using the processor, an anomalous glucose level reading not conforming to the glucose level pattern to determine
whether the anomalous glucose level reading has the similar shape;

adjusting, using the processor, the anomalous glucose level reading to adapt to the glucose level pattern to form an adapted
glucose level pattern if the anomalous glucose level reading has the similar shape;

filtering out, using the processor, the anomalous glucose level reading if the anomalous glucose level reading does not have
the similar shape;

calculating, using the processor, an insulin dosage for the time period beginning at the common event occurrence based on
the adapted glucose level pattern; and

initiating an action, wherein the action includes at least one of recommending the calculated dosage and automatically delivering
the calculated insulin dosage,

wherein the method is implemented on a portable medical system.

US Pat. No. 9,307,936

POLAR PLOT TO REPRESENT GLUCOSE SENSOR PERFORMANCE

Medtronic Minimed, Inc., ...

1. A method comprising:
obtaining a plurality of blood glucose reference samples from a patient;
obtaining a plurality of glucose sensor measurements using a glucose sensor in contact with the patient;
computing a first rate of change in blood glucose concentration as observed from two or more of the plurality of blood glucose
reference samples;

computing a second rate of change in the blood glucose concentration as observed from two or more of the plurality of glucose
sensor measurements;

generating an angular coordinate and a radial coordinate of a polar plot,
wherein the angular coordinate is a function of the first rate of change and the second rate of change, and
wherein the radial coordinate is proportional to a magnitude of a blood glucose concentration of the patient as measured from
one or more of the plurality of blood glucose reference samples; and

generating signals to present a graphical representation of a value on the polar plot in a visual medium, wherein the value
corresponds to the angular coordinate and the radial coordinate, and

wherein the computing the first rate of change, the computing the second rate of change, the generating the angular coordinate
and the radial coordinate, and the generating signals to present the graphical representation are performed by one or more
processors.

US Pat. No. 9,265,455

METHODS AND SYSTEMS FOR OPTIMIZING SENSOR FUNCTION BY THE APPLICATION OF VOLTAGE

Medtronic MiniMed, Inc., ...

1. A method of initializing a sensor, comprising:
determining a disconnection time, wherein the disconnection time is the amount of time a sensor has been disconnected from
sensor electronics,

wherein the sensor is an analyte sensor,
selecting an initialization protocol based on the disconnection time, the initialization protocol selected from the group
consisting of:

a first initialization scheme comprising a first series of voltage pulses and a second initialization scheme comprising a
second series of voltage pulses,

wherein the first initialization scheme is selected if the disconnection time falls within a first time range and the second
initialization scheme is selected if the disconnection time falls within a second time range; and

applying the selected initialization protocol to the sensor.

US Pat. No. 9,056,165

INTELLIGENT THERAPY RECOMMENDATION ALGORITHM AND METHOD OF USING THE SAME

Medtronic MiniMed, Inc., ...

1. A method of automatically making a therapy recommendation to adjust a stored insulin pump parameter, the method comprising
the steps of:
obtaining a blood glucose value at the end of a time interval;
determining if an intervening event occurred during the time interval before the blood glucose value was obtained, wherein
the intervening event includes at least one of a meal, a correction bolus, and an error code that changes the blood glucose
value unrelated to the stored pump parameter and thereby interferes with recommending a change to the stored pump parameter;

recommending no change to the stored pump parameter based on the blood glucose value if the intervening event occurred during
the time interval before the blood glucose value was obtained;

updating a recommended change to the stored pump parameter based on a previous recommended change to the stored pump parameter
and the difference between the blood glucose value and a target blood glucose level if no intervening event occurred during
the time interval;

comparing an absolute value of the updated recommended change to a predefined threshold value of the stored pump parameter,
wherein the predefined threshold value is 0.05 or 0.1 U/h when the stored pump parameter is a basal rate, the predefined threshold
value is 5 grams carbohydrates per unit of insulin when the stored pump parameter is a carbohydrate-to-insulin ratio (CR),
and the predefined threshold value is 5 mg/dl for a Unit of insulin when the stored pump parameter is an insulin sensitivity
factor (ISF);

making the therapy recommendation if the updated recommended change exceeds the threshold and the therapy recommendation is
within safety parameters; and

displaying the therapy recommendation to adjust the stored pump parameter.

US Pat. No. 9,265,881

THERAPEUTIC AGENT INJECTION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An injection device for delivering a therapeutic agent to a patient, the injection device comprising:
a body having a patient face and a port face opposite the patient face, the port face having an introducer port including
an introducer channel and an injection port including an injection channel, the introducer channel being in fluid communication
with the injection channel, the injection channel defining an injection axis;

a delivery tube for subcutaneous delivery of the therapeutic agent to the patient, the delivery tube projecting from and being
generally perpendicular to the patient face, the delivery tube defining an introducer axis and being in fluid communication
with the injection port;

a patch attached to the patient face and operable to adhesively attach to the patient; and
an injection adapter assembly removably connected to the injection port, the injection adapter assembly receiving a needleless
pen injector;

wherein the body has a first body portion including the port face and a second body portion including the patient face, the
first body portion and the second body portion being rotatably connected with a flange, the first body portion and the second
body portion being independently rotatable about the introducer axis.

US Pat. No. 9,267,875

ACCELERATED LIFE TESTING DEVICE AND METHOD

MEDTRONIC MINIMED, INC., ...

12. An accelerated life testing device for use on a test piece, the device comprising:
a test chamber for containing the test piece; and
an atmospheric controller operably connected to the test chamber, the atmospheric controller being operable to control temperature
and humidity within the test chamber;

wherein the atmospheric controller is operable to form an oxidation layer on the test piece by:
establishing a first atmosphere within the test chamber;
changing the first atmosphere to a second atmosphere to form a deposition layer on the test piece;
changing the second atmosphere to the first atmosphere to remove the deposition layer from the test piece; and
repeating the changing the first atmosphere to the second atmosphere and the changing the second atmosphere to the first atmosphere
to form the oxidation layer on the test piece.

US Pat. No. 9,089,641

AUTOMATED FILLING SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A system for automated pressure equalization, the system comprising:
a transfer guard, the transfer guard comprising:
a first needle having a fluid path for transferring fluidic media from an interior volume of a vial to an interior volume
of a reservoir;

a second needle having a fluid path for communicating between atmosphere and the interior volume of the vial; and
a bias member connected between an end of the reservoir and a plunger head positioned in the reservoir, the bias member for
providing a force behind the plunger head as the plunger head is moved within the reservoir to transfer fluidic media from
the interior volume of the vial to the interior volume of the reservoir;

the bias member and the transfer guard configured to equalize pressure relative to atmosphere in the interior volume of the
vial in a case where the second needle communicates between atmosphere and the interior volume of the vial and the plunger
head is moved within the reservoir to transfer fluidic media from the interior volume of the vial to the interior volume of
the reservoir.

US Pat. No. 9,231,617

MEDICAL DEVICE WITH MEMBRANE KEYPAD SEALING ELEMENT, AND RELATED MANUFACTURING METHOD

Medtronic MiniMed, Inc., ...

1. A medical device comprising:
a housing having a front face, a keypad mounting cavity on the front face, and a sealing rim on the front face, the sealing
rim surrounding the keypad mounting cavity;

a membrane keypad assembly coupled to the housing and positioned inside the keypad mounting cavity, the membrane keypad assembly
comprising a plurality of actuation components integrated therein;

a sealing element comprising a perimeter area, the sealing element overlying the membrane keypad assembly such that the perimeter
area extends beyond the membrane keypad assembly, and the perimeter area coupled to the sealing rim to form a fluid resistant
seal with the housing; and

a graphic keypad overlay removably adhered to the sealing element to be replaceable with a different graphic keypad overlay,
the graphic keypad overlay comprising graphical representations corresponding to the actuation components.

US Pat. No. 9,265,884

ON-BODY INJECTOR AND METHOD OF USE

MEDTRONIC MINIMED, INC., ...

1. An on-body injector for use with a patient with an injection device having an injection port in fluid communication with
a delivery tube, the injection port lying on an injection axis, the on-body injector comprising:
a bolus reservoir;
a bolus injection needle in fluid communication with the bolus reservoir, the bolus injection needle having a bolus injection
needle tip aligned with the injection port, the bolus injection needle being slideably biased away from the injection port
to define a gap between the bolus injection needle tip and the injection port; and

a button operably connected to the bolus injection needle to slide the bolus injection needle along the injection axis;
wherein the button is operable to advance the bolus injection needle tip to close the gap and advance the bolus injection
needle tip into the injection port to form an injection flow path from the bolus reservoir, through the bolus injection needle,
through the delivery tube, and into the patient;

wherein the button is further operable to advance a plunger through the bolus reservoir to deliver a predetermined bolus volume
to the patient through the injection flow path; and

a pressurized reservoir in fluid communication with the bolus reservoir.

US Pat. No. 9,199,043

SYRINGE PISTON WITH CHECK VALVE SEAL

Medtronic MiniMed, Inc., ...

1. A syringe piston comprising:
a piston body having a fluid end and an actuator end opposite the fluid end;
a piston seal coupled to the piston body and located between the fluid end and the actuator end, wherein the piston seal forms
an interference fluid seal with an interior wall of a syringe barrel;

a check valve seal coupled to the piston body and positioned such that the piston seal is located between the check valve
seal and the actuator end, the check valve seal having a major outer surface that faces a main fluid chamber of the syringe
barrel; and

a gas entrapment zone defined between the check valve seal and the piston seal, wherein the check valve seal allows one-way
gas flow from the main fluid chamber of the syringe barrel and into the gas entrapment zone, and the piston seal inhibits
or prevents gas flow from the gas entrapment zone.

US Pat. No. 9,320,470

METHOD AND/OR SYSTEM FOR SENSOR ARTIFACT FILTERING

Medtronic Minimed, Inc., ...

1. A method comprising:
obtaining a sensor signal from a blood glucose sensor of a sensor component of an apparatus, the sensor signal being representative
of a blood glucose concentration;

mapping a measurement of noise associated with the sensor signal to one of three or more discrete levels or values;
selecting an output signal for use in determining an estimate of the blood glucose concentration from among a plurality of
distinct signal-filter paths arranged concurrently based, at least in part, on the one of three or more discrete levels or
values;

generating one or more commands for an insulin delivery component of the apparatus based, at least in part, on the estimate
of the blood glucose concentration; and

transmitting the generated one or more commands to the insulin delivery component to regulate a rate of fluid infusion into
a body.

US Pat. No. 9,393,363

INSERTION DEVICE SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. An insertion system, the insertion system comprising:
a housing;
a piercing member arranged partially within the housing, the piercing member having a piercing end located outside of the
housing for piercing a membrane, the piercing member having a hollow interior for conveying fluidic media; and

a compliant material arranged within the housing to support the piercing member and attach the piercing member to the housing,
the compliant material for allowing articulation of the piercing member relative to the housing in a case where the piercing
member is in the membrane and moved relative to the housing;

wherein the piercing member extends through the compliant material and has a first end located on an opposite side of the
compliant material with respect to the piercing end of the piercing member.

US Pat. No. 9,309,550

ANALYTE SENSORS HAVING NANOSTRUCTURED ELECTRODES AND METHODS FOR MAKING AND USING THEM

Medtronic MiniMed, Inc., ...

1. A method of sensing glucose within the body of a mammal, the method comprising implanting a glucose sensor into a mammal,
wherein the glucose sensor comprises:
a base layer;
a conductive layer disposed upon the base layer wherein the conductive layer includes a working electrode comprising a plurality
of conductive nanotubes;

an analyte sensing layer comprising glucose oxidase disposed on the conductive nanotubes, wherein the glucose oxidase generates
hydrogen peroxide in the presence of glucose; and

an analyte modulating layer disposed on the analyte sensing layer, wherein the analyte modulating layer:
modulates the diffusion of glucose therethrough; and
includes a composition of matter comprising a hydrophilic comb-copolymer having a central chain and a plurality of side chains
coupled to the central chain, wherein at least one side chain comprises a silicone moiety; and

sensing an alteration in electrical potential at the working electrode that results from hydrogen peroxide produced by the
glucose oxidase in the presence of glucose;

and correlating the alteration in electrical potential with the presence of glucose, so that glucose is sensed.

US Pat. No. 9,393,399

SEALING ASSEMBLY FOR A FLUID RESERVOIR OF A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A sealing element for a fluid infusion device comprising a hollow fluid delivery needle, the sealing element comprising:
a base section;
a retractable body section extending from the base section;
a tip section extending from the retractable body section, wherein the retractable body section is between the base section
and the tip section;

a needle cavity formed in the retractable body section and continuing through the base section to define a needle opening
in the base section, the needle cavity sized to receive the hollow fluid delivery needle;

a self-sealing slit formed in the tip section to accommodate the hollow fluid delivery needle when the sealing element is
in a retracted position;

a guide channel in communication with the needle cavity and the self-sealing slit, the guide channel located between an end
of the needle cavity and the self-sealing slit, wherein the guide channel leads a tip of the hollow fluid delivery needle
into the self-sealing slit during retraction of the sealing element; and

a needle seal located in the guide channel and positioned between the self-sealing slit and the needle cavity to form a fluid
seal around the hollow fluid delivery needle to fluidly separate the needle cavity from the guide channel.

US Pat. No. 9,308,321

INFUSION DEVICE HAVING GEAR ASSEMBLY INITIALIZATION

Medtronic MiniMed, Inc., ...

1. An infusion device comprising:
a housing to receive a shaft coupled to a plunger disposed in a reservoir;
a gear assembly including a first gear to engage the shaft and a worm gear coupled to the first gear, the first gear having
rotational freedom in a direction opposite a delivery direction, the worm gear exhibiting axial displacement in a first direction
in response to rotation of the first gear in the direction opposite the delivery direction;

a force sensor aligned with an axle of the worm gear;
a motor having a rotor coupled to the gear assembly; and
a control module coupled to the motor to operate the motor to displace the axle of the worm gear in a second direction opposite
the first direction and away from the force sensor in response to the reset condition.

US Pat. No. 9,199,030

INFUSION MEDIUM DELIVERY DEVICE AND METHOD WITH DRIVE DEVICE FOR DRIVING PLUNGER IN RESERVOIR

Medtronic MiniMed, Inc., ...

1. A medical device for delivering an infusion medium to a user, the medical device comprising:
a first housing portion adapted to be carried by a user;
a second housing portion configured to be selectively operatively engaged with and disengaged from the first housing portion;
a reservoir connected to one of the first and second housing portions;
at least one of a drive device or a needle inserting device supported by the other of the first and second housing portions
relative to the respective housing portion to which the reservoir is connected, such that upon the first and second housing
portions being operatively engaged, the reservoir is operatively coupled to at least one of the drive device or the needle
inserting device;

a first magnet supported on the first housing portion; and
a second magnet supported on the second housing portion in a position to magnetically interact with the first magnet upon
the first and second housing portions being improperly aligned when brought toward each other for operative engagement;

wherein the first and second magnets are positioned relative to each other so as to impart a repelling force directed toward
properly aligning the first and second housing portions for operative engagement.

US Pat. No. 9,089,292

CALIBRATION OF GLUCOSE MONITORING SENSOR AND/OR INSULIN DELIVERY SYSTEM

Medtronic Minimed, Inc., ...

1. A method comprising:
obtaining, from a blood-glucose sensor, one or more blood glucose sensor measurements;
obtaining one or more reference sample signals based at least in part on one or more blood glucose reference samples;
combining, via a processor, said one or more reference sample signals and said one or more blood glucose measurements to provide
a plurality of blood glucose reference sample-sensor measurement pairs;

estimating one or more parameters of a plurality of probability models based, at least in part, on said blood glucose reference
sample-sensor measurement pairs;

determining a plurality of functions for estimating a blood-glucose concentration in a patient from sensor measurements based,
at least in part, on said estimated one or more parameters of said plurality of probability models;

for each of said plurality of functions, estimating a sensor glucose concentration value by application of said function to
provide a plurality of estimated sensor glucose concentration values, each of said estimated sensor glucose concentration
values being generated by a corresponding one of said plurality of functions; and

determining a composite sensor glucose concentration value for the patient based, at least partly, on a combination of said
plurality of estimated sensor glucose concentration values.

US Pat. No. 9,433,732

METHODS AND APPARATUSES FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP

MEDTRONIC MINIMED, INC., ...

1. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:
a housing;
a drive mechanism including a motor and one or more drive train components contained within the housing and operatively coupled
to the reservoir to deliver fluid from the reservoir through a fluid path into the body of the user;

one or more electronic components to measure a plurality of respective values of at least two different parameters associated
with the motor or one of the drive train components; and

a processor contained within the housing, wherein the processor calculates a respective average value based on said plurality
of measured values for each of the at least two different parameters, and wherein the processor adds said respective average
values to obtain a combined value and determines whether an occlusion has occurred in the fluid path of the infusion pump
by using the combined value.

US Pat. No. 9,215,995

SENSOR SYSTEMS HAVING MULTIPLE PROBES AND ELECTRODE ARRAYS

Medtronic MiniMed, Inc., ...

1. An amperometric analyte sensor system comprising:
a probe platform;
a first probe coupled to the probe platform and adapted to be inserted in vivo, wherein the first probe comprises:
a first electrode array comprising a working electrode, a counter electrode and a reference electrode; and
a second electrode array comprising a working electrode, a counter electrode and a reference electrode;
a second probe coupled to the probe platform and adapted to be inserted in vivo, wherein the second probe comprises:
a third electrode array comprising a working electrode, a counter electrode and a reference electrode; and
a fourth electrode array comprising a working electrode, a counter electrode and a reference electrode;wherein the first, second, third and fourth electrode arrays are configured to be electronically independent of one another;
and
the system further comprises:
a processor;
a computer-readable program code having instructions, which when executed cause the processor to:
assess signal data obtained from each of the first, second, third and fourth electrode arrays against one or more reliability
parameters;

rank signal data from each of the first, second, third and fourth electrode arrays in accordance with the assessment against
the one or more reliability parameters; and

compute an analyte concentration based upon the ranking of signal data obtained from each of the first, second, third and
fourth electrode arrays.

US Pat. No. 9,213,010

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of calibrating a sensor during a period of sensor transition, the method comprising:
defining an electrochemical impedance spectroscopy (EIS)-based sensor status vector (V) for each one of a plurality of sensor
current (Isig)-blood glucose (BG) pairs;

monitoring the status vectors for the plurality of Isig-BG pairs over time;
detecting when there is a difference between a first status vector for a first Isig-BG pair and a subsequent status vector
for a subsequent Isig-BG pair, said first Isig-BG pair having assigned thereto a first offset value; and

if a magnitude of said difference is larger than a predetermined threshold, assigning a dynamic offset value for said subsequent
Isig-BG pair that is different from said first offset value so as to maintain a substantially linear relationship between
said subsequent Isig and said subsequent BG.

US Pat. No. 9,125,608

REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD

MEDTRONIC MINIMED, INC., ...

1. A system for calibrating a sensor of a characteristic monitoring system in real time by determining, and compensating for,
an IR drop across unwanted resistances in a cell, said sensor including a counter electrode, a reference electrode, and a
working electrode in communication with a user's blood or interstitial fluids to produce signals indicative of said characteristic,
the system comprising:
a first control unit having a potentiostat, said potentiostat including an operational amplifier connected in an electrical
circuit to maintain substantial equality between the magnitude of a measured voltage across the sensor's working and reference
electrodes and the magnitude of an applied voltage;

a current-interrupt switch electrically connected between the operational amplifier's output and the sensor's counter electrode
to provide a closed circuit when the switch is closed and an open circuit when the switch is opened; and

a second control unit including a microprocessor and connected in the electrical circuit to maintain substantial equality
between the magnitude of an optimally desired voltage across the sensor's working and reference electrodes and the magnitude
of an effective amount of potential in the cell that drives electrochemical reactions at the working electrode, said effective
amount of potential reflecting an adjustment for the magnitude of said IR drop, and said second control unit providing said
applied voltage as an input to the operational amplifier,

wherein the second control unit estimates the magnitude of the IR drop through linear regression of acquired open-circuit
samples of said measured voltage across the sensor's working and reference electrodes over time;

wherein the magnitude of said effective amount of potential in the cell is optimized by further subtracting therefrom the
magnitude of the open-circuit voltage across the sensor's working and reference electrodes; and

wherein the magnitude of said open-circuit voltage is obtained by allowing, while said switch remains open, the voltage between
the working and reference electrodes to stabilize to a steady-state value, and then measuring said steady-state value.

US Pat. No. 9,089,637

RESERVOIR PLUNGER HEAD SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A system for transferring fluidic media, the system comprising:
a plunger head moveable in an axial direction within a reservoir having an interior volume for containing fluidic media, the
plunger head comprising:

a first portion in contact with fluidic media when fluidic media is in the interior volume of the reservoir;
a second portion located on an opposite side of the first portion of the plunger head from the interior volume of the reservoir,
the second portion connectable to a plunger arm; and

a third portion located between the first portion and the second portion of the plunger head;
wherein the first portion, the second portion, and the third portion of the plunger head are supported for moving together
in the axial direction within the reservoir; and

at least one seal member positioned between the reservoir and the plunger head;
wherein the at least one seal member is positioned between the first portion and the second portion of the plunger head;
wherein the first portion of the plunger head has an outer diameter, the second portion of the plunger head has an outer diameter
and the third portion of the plunger head between the first portion and the second portion has an outer diameter that is reduced
relative to the outer diameters of the first portion and the second portion of the plunger head, and wherein the at least
one seal member comprises a seal located around the third portion of the plunger head; and

wherein the first portion comprises at least one protrusion arranged along an outer surface defined by the outer diameter
of the first portion, the at least one protrusion is configured for at least one of stabilizing the plunger head and controlling
the compression of the at least one seal member.

US Pat. No. 9,101,310

GLUCOSE SENSOR SIGNAL STABILITY ANALYSIS

Medtronic Minimed, Inc., ...

1. A method comprising:
obtaining a series of samples of at least one sensor signal is responsive to a blood glucose level of a patient;
determining, based at least partly on the series of samples, at least one metric assessing an underlying trend of a change
in responsiveness of the at least one sensor signal to the blood glucose level of the patient over time, wherein said determining
comprises: iteratively updating a trend estimation at multiple samples of the series of samples of the at least one sensor
signal based at least partly on a trend estimation at a previous sample and a growth term; and

assessing a reliability of the at least one sensor signal to respond to the blood glucose level of the patient based at least
partly on the at least one metric assessing an underlying trend.

US Pat. No. 9,101,715

HANDHELD PERSONAL DATA ASSISTANT (PDA) WITH A MEDICAL DEVICE AND METHOD OF USING THE SAME

MEDTRONIC MINIMED, INC., ...

1. A medical system, comprising:
an external infusion device to deliver insulin to a user;
a characteristic meter to receive a blood sample from the user to determine a glucose level of the user;
a sensor set to determine body characteristics on a continuous, near continuous, or intermittent basis, wherein the body characteristics
include glucose levels of the user, the sensor set is coupled to a telemetered characteristic monitor transmitter to transmit
sensor data including the body characteristics, and wherein the sensor set includes one of an implantable sensor, a subdermal
sensor, and a subcutaneous sensor; and

a characteristic monitor, including
a display having a touch screen to display the sensor data received from the sensor set,
a sensor interface to wirelessly receive the sensor data from the sensor set via the telemetered characteristic monitor transmitter,
and

a microprocessor to program and obtain data from the external infusion device, to coordinate the sensor data from the sensor
set and meter data, including the determined glucose level of the user, from the characteristic meter with the data from the
external infusion device, to program and control the external infusion device, and to update delivery parameters of the external
infusion device,

wherein the characteristic meter transmits the meter data of the glucose level of the user from the characteristic meter to
the microprocessor of the characteristic monitor.

US Pat. No. 9,486,577

FLUID RESERVOIR SEATING PROCEDURE FOR A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A method of seating a fluid reservoir in a housing of a fluid infusion device prior to establishing an outgoing fluid flow
path from the fluid reservoir, the fluid infusion device comprising a drive motor assembly, an actuation mechanism operatively
coupled to the drive motor assembly for actuation of a plunger of the fluid reservoir, and a force sensor operatively coupled
to the actuation mechanism, the method comprising:
detecting insertion of the fluid reservoir into the housing, wherein insertion of the fluid reservoir into the housing causes
a shaft of the plunger to engage the actuation mechanism;

after detecting insertion of the fluid reservoir, obtaining a first measure of force using the force sensor, wherein the first
measure of force is associated with interaction of the shaft with the actuation mechanism;

comparing the first measure of force to a first threshold force value;
when the first measure of force is greater than the first threshold force value, depressurizing the fluid reservoir;
after depressurizing the fluid reservoir, or when the first measure of force is not greater than the first threshold force
value, rewinding the drive motor assembly to achieve an equilibrium state for the fluid reservoir; and

after rewinding the drive motor assembly to achieve the equilibrium state, advancing the drive motor assembly to obtain an
initial seated state for the fluid reservoir.

US Pat. No. 9,226,709

ICE MESSAGE SYSTEM AND METHOD

Medtronic MiniMed, Inc., ...

1. A medical system for use with a patient, the system comprising:
a personal medical device attached to the patient, the personal medical device comprising:
a case attached to the patient;
a monitor contained in the case and operable to detect an emergency condition at the personal medical device; and
a processor contained in the case and operably connected to the monitor and operable to select an ICE message in response
to the emergency condition; and

a display operably connected to the personal medical device and operable to display the ICE message, the ICE message including
emergency contact information.

US Pat. No. 9,204,840

REAL TIME SELF-ADJUSTING CALIBRATION ALGORITHM

Medtronic Minimed, Inc., ...

1. A method for filtering signals from a sensor comprising:
receiving a plurality of signal values from the sensor generated in response to a concentration of a substance;
at a processor, computing a quantifier of a variance of a measurement error based, at least in part, on a standard deviation
of an absolute value of consecutive data points within the plurality of signal values; and

at said processor, filtering the plurality of signal values with an adaptive filter, wherein the quantifier is an input to
the adaptive filter.

US Pat. No. 9,370,621

NEEDLE INSERTION SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A needle-inserting device comprising:
a housing having a flexible portion, an internal chamber, a longitudinal dimension, and an internal surface having an angled,
ramped or wedge-shaped portion;

a plunger arranged for movement within the internal chamber, in the direction of the longitudinal dimension of the housing,
from a first plunger position to a second plunger position;

a bias mechanism for imparting a bias force on the plunger when the plunger is in the first plunger position, wherein the
bias force is directed toward the second plunger position; and

a needle connected to the plunger for movement with the plunger; and
a tab connected to or integral with and the plunger and carried by the plunger, the tab having a tab end configured to retain
the plunger in the first plunger position, the tab end moveable relative to the housing;

an insert structure arranged for movement within the internal chamber of the housing with movement of the plunger from the
first plunger position to the second plunger position, the insert structure including a body through which the needle extends,
wherein at least one of the plunger or the body of the insert structure is arranged to engage the angled, ramped or wedge-shaped
portion of the housing and outwardly flex the flexible portion of the housing upon the insert structure being moved as the
plunger moves from the first plunger position to the second plunger position;

wherein upon movement of the tab end, the plunger is released from being retained in the first plunger position by the tab
end and moves with the tab end, relative to the housing, in the direction of the longitudinal dimension of the housing from
the first plunger position to the second plunger position under the bias force imparted by the bias mechanism to move the
needle to an insert position and outwardly flex the flexible portion of the housing.

US Pat. No. 9,327,073

METHOD AND APPARATUS FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP

MEDTRONIC MINIMED, INC., ...

1. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:
a housing;
a drive mechanism including a motor and one or more drive components contained within the housing and operatively coupled
to the reservoir to deliver fluid from the reservoir through a fluid path into the body of the user;

one or more electronic components to take a series of measurements of a parameter associated with the motor or one of the
drive train components; and

a controller contained within the housing, wherein the controller filters the series of measurements to remove at least one
measurement from the series of measurements, calculates a weighted average of the remaining measurements in the series of
measurements by applying a weighting factor to each remaining measurement in the series of measurements to determine a weighted
value corresponding to each said remaining measurement and calculating the average of the weighted values, the weighting factor
applied to each said remaining measurement after the first remaining measurement being larger than the weighting factor for
the immediately preceding remaining measurement, compares the weighted average to a maximum threshold value, and determines
whether an occlusion has occurred in the fluid path of the infusion pump by determining whether the weighted average is greater
than the maximum threshold value.

US Pat. No. 9,283,318

FLANGED SEALING ELEMENT AND NEEDLE GUIDE PIN ASSEMBLY FOR A FLUID INFUSION DEVICE HAVING A NEEDLED FLUID RESERVOIR

Medtronic MiniMed, Inc., ...

1. A sealing assembly for a fluid infusion device that cooperates with a fluid reservoir having a reservoir port and a hollow
fluid reservoir needle at least partially located within the reservoir port, the sealing assembly comprising:
a reservoir port receptacle to receive the reservoir port, and comprising a proximal end, a distal end extending from the
proximal end, and a needle entry formed in the distal end to receive the hollow fluid reservoir needle;

a fluid chamber located at least partially in the reservoir port receptacle; and
a sealing component positioned in the reservoir port receptacle to cooperate with the fluid chamber, the sealing component
comprising:

a needle guide pin protruding from the proximal end of the reservoir port receptacle, wherein an end section of the needle
guide pin is sized to fit within the hollow fluid reservoir needle; and

a needle sealing element that cooperates with the hollow fluid reservoir needle and with the needle guide pin, the needle
sealing element comprising a base section adjacent to the fluid chamber, an end section opposite the base section, a neck
section between the base section and the end section, and a needle opening extending through the neck section; wherein:

when the reservoir port is engaged with reservoir port receptacle, the end section of the needle guide pin resides within
the hollow fluid reservoir needle, a portion of the hollow fluid reservoir needle resides within the needle opening, and the
needle sealing element forms a first seal around an exterior surface of the hollow fluid reservoir needle; and

when the reservoir port is disengaged from the reservoir port receptacle, the hollow fluid reservoir needle is decoupled from
the sealing component, a portion of the end section of the needle guide pin resides within the needle opening, and the needle
sealing element forms a second seal around an exterior surface of the needle guide pin.

US Pat. No. 9,233,203

MEDICAL NEEDLES FOR DAMPING MOTION

Medtronic MiniMed, Inc., ...

1. A needle structure for communicating fluid to a patient from an external fluid reservoir configured to contain a flowable
fluid and having a pierceable septum external to the patient, the needle structure comprising a hollow needle having a longitudinal
dimension, a first end affixed to the fluid reservoir, and a second end having a sharp end for inserting the needle into the
patient, wherein force applied to the first end of the needle pushes the needle through the pierceable septum to position
the needle in fluid flow communication with the fluid reservoir and to insert the second end of the needle into the patient,
the hollow needle further having a generally straight section extending along the longitudinal dimension adjacent the first
end, the generally straight section passing through the pierceable septum external to the patient, a passage along at least
a portion of its longitudinal dimension for conveying the flowable fluid to the patient and at least one bend along its longitudinal
dimension between the generally straight section and the second end that dampens movements of the second end with respect
to the first end, the needle being flexible at the at least one bend and flexes to dampen the transfer of motion from the
second end of the needle to the generally straight section of the needle.

US Pat. No. 9,338,819

VARIABLE DATA USAGE PERSONAL MEDICAL SYSTEM AND METHOD

MEDTRONIC MINIMED, INC., ...

15. A method of personal medical variable data usage for a patient comprising:
transmitting a value for a fixed interval index remote from the patient;
storing the fixed interval index at the patient;
generating self-care device data for the patient;
transmitting the self-care device data at a fixed interval;
receiving and storing the transmitted self-care device data;
storing an interval counter and incrementing the interval counter for each of the fixed intervals in which the transmitted
self-care device data is received;

generating a data cellular packet from overhead plus the stored self-care device data in response to determining that the
interval counter equals the fixed interval index;

transmitting the data packet from the patient over a cellular network, wherein the fixed interval index controls how often
data packets are transmitted; and

receiving, processing, and storing the transmitted data packet remote from the patient.

US Pat. No. 9,379,653

DYNAMIC PULSE-WIDTH MODULATION MOTOR CONTROL AND MEDICAL DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. A method of controlling a motor, the method comprising:
applying a modulated voltage to the motor to produce a commanded rotation of a rotor of the motor;
determining an expected displacement based on the commanded rotation;
obtaining a measured displacement influenced by rotation of the rotor in response to applying the modulated voltage to the
motor to produce the commanded rotation; and

adjusting a duty cycle of the modulated voltage in response to a difference between the expected displacement and the measured
displacement.

US Pat. No. 9,364,609

INSULIN ON BOARD COMPENSATION FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM

Medtronic MiniMed, Inc., ...

1. An electronic insulin infusion device comprising:
an insulin reservoir for insulin to be delivered from the insulin infusion device to a body of a user;
a processor architecture comprising at least one processor device; and at least one memory element associated with the processor
architecture, the at least one memory element storing processor-executable instructions that, when executed by the processor
architecture, perform a method of controlling closed-loop delivery of insulin from the insulin reservoir to the body of the
user, the method comprising:

computing a current insulin on board (IOB) value that indicates an amount of active insulin in the body of the user;
calculating an IOB rate based at least in part on the computed IOB value, wherein the IOB rate represents an amount of active
insulin accumulated from manual boluses in the body of the user per unit of time;

determining an adjusted insulin infusion rate based at least in part on the calculated IOB rate and an uncompensated insulin
infusion rate;

selecting a final insulin infusion rate for the insulin infusion device, wherein the selecting selects either the determined
adjusted insulin infusion rate, the uncompensated insulin infusion rate, or a current basal rate as the final insulin infusion
rate, wherein selecting the final insulin infusion rate is in accordance with either expression FinalRate(n)=max(Basal; AdjustedRate(n))
when PIDRate>Basal, or expression FinalRate(n)=PIDRate(n) when PIDRate Basal, wherein:

FinalRate(n) is the selected final insulin infusion rate;
Basal is the current basal rate;
AdjustedRate(n) is the determined adjusted insulin infusion rate; and
PIDRate(n) is the uncompensated insulin infusion rate; and
operating the insulin infusion device in a closed-loop mode to continuously deliver insulin from the insulin reservoir to
the body of the user in accordance with the final insulin infusion rate that is selected, wherein the final insulin infusion
rate represents an amount of insulin to be delivered per unit of time.

US Pat. No. 9,408,567

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of performing real-time sensor diagnostics on a subcutaneous or implanted sensor having at least one working electrode,
comprising:
(a) performing a first electrochemical impedance spectroscopy (EIS) procedure to generate a first set of impedance-related
data for the at least one working electrode;

(b) after a predetermined time interval, performing a second EIS procedure to generate a second set of impedance-related data
for the at least one electrode; and

(c) based on the first and second sets of impedance-related data, deteimining whether the sensor is functioning normally,
wherein each of the first and second sets of impedance-related data includes data for at least one impedance-related parameter
that is substantially glucose-independent, wherein said at least one substantially glucose-independent impedance-related parameter
is imaginary impedance, and wherein the imaginary impedance is measured at a frequency of at least 1 kHz.

US Pat. No. 9,050,406

OCCLUSION DETECTION FOR A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A method of detecting occlusions in a fluid path of a fluid infusion device having a drive motor assembly that actuates
a fluid reservoir by applying actuation force to a piston of the fluid reservoir, the method comprising:
initiating a fluid delivery action intended to deliver an amount of fluid from the fluid reservoir;
determining measures of fluid pressure in the fluid path for the fluid delivery action;
indicating an occlusion when a first rate of change of the measures of fluid pressure is greater than or equal to first threshold
value, the first rate of change based upon a first measurement window; and

indicating an occlusion when both: (a) a second rate of change of the measures of fluid pressure is greater than or equal
to a second threshold value, the second rate of change based upon a second measurement window; and (b) a current measure of
fluid pressure is greater than or equal to a threshold force value.

US Pat. No. 9,522,223

SYSTEMS FOR FLUID RESERVOIR RETENTION

Medtronic MiniMed, Inc., ...

1. A housing for a fluid infusion device, comprising:
a first housing component including a first engagement system, the first housing component defining a first compartment and
a second compartment, the first engagement system coupled to the second compartment so as to be disposed within the second
compartment, the first engagement system including a wedge movable within the second compartment between a first position
and a second position, and the first engagement system includes a retention member immovably mounted in the second compartment
and a first biasing member coupled about the retention member that biases the wedge into the first position, the wedge defining
a throughbore that slidably receives the retention member and a portion of the first biasing member; and

a second housing component coupled to the first compartment of the first housing component and including a second engagement
system, the second engagement system movable within the second housing component between a first position and a second position.

US Pat. No. 9,125,607

REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD

MEDTRONIC MINIMED, INC., ...

1. A system for calibrating a sensor of a characteristic monitoring system in real time by determining, and compensating for,
an IR drop across unwanted resistances in a cell, said sensor including a counter electrode, a reference electrode, and a
working electrode in communication with a user's blood or interstitial fluids to produce signals indicative of said characteristic,
the system comprising:
a first control unit having a potentiostat, said potentiostat including an operational amplifier connected in an electrical
circuit to maintain substantial equality between the magnitude of a measured voltage across the sensor's working and reference
electrodes and the magnitude of an applied voltage;

a current-interrupt switch electrically connected between the operational amplifier's output and the sensor's counter electrode
to provide a closed circuit when the switch is closed and an open circuit when the switch is opened; and

a second control unit including a microprocessor and connected in the electrical circuit to maintain substantial equality
between the magnitude of an optimally desired voltage across the sensor's working and reference electrodes and the magnitude
of an effective amount of potential in the cell that drives electrochemical reactions at the working electrode, said effective
amount of potential reflecting an adjustment for the magnitude of said IR drop, and said second control unit providing said
applied voltage as an input to the operational amplifier,

wherein the second control unit estimates the magnitude of the IR drop through linear regression of acquired open-circuit
samples of said measured voltage across the sensor's working and reference electrodes over time and then calculates the magnitude
of said effective amount of potential in the cell by subtracting the magnitude of the IR drop from the closed-circuit magnitude
of said measured voltage across the sensor's working and reference electrodes; and

wherein the magnitude of said effective amount of potential in the cell is optimized by further subtracting therefrom the
magnitude of the open-circuit voltage across the sensor's working and reference electrodes.

US Pat. No. 9,808,191

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of calibrating a sensor during a period of sensor transition, the method comprising:
defining an electrochemical impedance spectroscopy (EIS)-based sensor status vector (V) for each one of a plurality of sensor
current (Isig)-blood glucose (BG) pairs;

defining an Isig buffer to store Isig values of said plurality of Isig-BG pairs;
defining an BG buffer to store BG values of said plurality of Isig-BG pairs;
monitoring the status vectors for the plurality of Isig-BG pairs over time;
detecting when there is a difference between a first status vector for a first Isig-BG pair and a subsequent status vector
for a subsequent Isig-BG pair;

if a magnitude of said difference is smaller than a predetermined threshold, calibrating said sensor based on values of said
Isig-BG pairs from a first set of Isig and BG buffers; and

if the magnitude of said difference is larger than a predetermined threshold, calibrating said sensor based on values of said
Isig-BG pairs from a second set of Isig and BG buffers, wherein said second set of Isig and BG buffers contains at least the
values of Isig and BG from said subsequent Isig-BG pair.

US Pat. No. 9,357,958

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of calculating a single, fused sensor glucose value based on respective glucose measurement signals of a plurality
of redundant sensing electrodes, comprising:
performing respective electrochemical impedance spectroscopy (EIS) procedures for each of the plurality of redundant sensing
electrodes to obtain values of at least one impedance-based parameter for each said sensing electrode;

measuring the electrode current (Isig) for each of the plurality of redundant sensing electrodes;
independently calibrating each of the measured Isigs to obtain respective calibrated sensor glucose values;
performing a bound check and a noise check on said measured Isig and said values of the at least one impedance-based parameter
and assigning a bound-check reliability index and a noise-check reliability index to each said sensing electrode;

performing signal-dip analysis based on one or more of said at least one impedance-based parameter and assigning a dip reliability
index to each said sensing electrode;

performing sensitivity-loss analysis based on one or more of said at least one impedance-based parameter and assigning a sensitivity-loss
index to each said sensing electrode;

for each of the plurality of electrodes, calculating a total reliability index based on said electrode's bound-check reliability
index, noise-check reliability index, dip reliability index, and sensitivity-loss reliability index;

for each of the plurality of electrodes, calculating a weight based on said electrode's total reliability index; and
calculating said single, fused sensor glucose value based on the respective weights and calibrated sensor glucose values of
each of the plurality of redundant sensing electrodes.

US Pat. No. 9,339,639

SEALING ASSEMBLY FOR A FLUID RESERVOIR OF A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A sealing assembly for a fluid infusion device, the sealing assembly comprising:
a durable housing that receives and mates with a removable fluid reservoir having a fluid delivery port extending from the
fluid reservoir and having a funnel-shaped interior defined therein, wherein the durable housing houses the removable fluid
reservoir and retains the removable fluid reservoir in a particular position and orientation;

a base plate having an adhesive layer of material to adhere the base plate to skin of a patient, and having a coupling structure
to removably couple the base plate to the durable housing of the fluid infusion device;

a reservoir port receptacle integrally formed with the base plate to receive and engage the fluid delivery port of the fluid
reservoir in the particular position and orientation when the durable housing is coupled to the base plate, wherein the fluid
delivery port of the fluid reservoir resides within the reservoir port receptacle when the durable housing is coupled to the
base plate;

a hollow fluid delivery needle coupled to the base plate and extending within the reservoir port receptacle to provide a fluid
flow path from the fluid reservoir to a user of the fluid infusion device when the durable housing is coupled to the base
plate; and

a sealing element coupled to the base plate and overlying at least a portion of the hollow fluid delivery needle, the sealing
element comprising:

a base section;
a tip section extending from the base section, the tip section shaped to enter and seal with the funnel-shaped interior of
the fluid delivery port when the durable housing is coupled to the base plate;

a retractable body section between the base section and the tip section;
a needle cavity formed in the retractable body section and continuing through the base section to define a needle opening
in the base section, the needle cavity sized to receive the hollow fluid delivery needle; and

a self-sealing slit formed in the tip section to accommodate the hollow fluid delivery needle when the sealing element is
in a retracted position caused by coupling of the durable housing with the base plate.

US Pat. No. 9,360,447

METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS

MEDTRONIC MINIMED, INC., ...

1. A sensor system, comprising:
a sensor configured to provide a sensor signal indicative of a physiological characteristic of a patient, the sensor including
a plurality of electrodes that are configured to be implanted or disposed subcutaneously within the patient's body so as to
be in continuous contact with the patient's bodily fluids; and

a sensor electronics device that is coupled to the sensor and includes:
an electrical detection circuit that determines whether the plurality of electrodes in the sensor are hydrated and, only after
said plurality of electrodes are hydrated, generates an interrupt; and

a microcontroller that receives the interrupt from the electrical detection circuit and transmits a signal representative
of a voltage to the sensor, wherein an electrode of the plurality of electrodes receives the voltage derived from the transmitted
signal.

US Pat. No. 9,402,949

DETECTING CONDITIONS ASSOCIATED WITH MEDICAL DEVICE OPERATIONS USING MATCHED FILTERS

Medtronic MiniMed, Inc., ...

1. A fluid infusion device comprising:
a motor operable to displace a plunger of a reservoir;
a sensing arrangement to provide an output indicative of a characteristic influenced by displacement of the plunger; and
a control module coupled to the sensing arrangement to:
identify a current physical delivery configuration for the fluid infusion device;
identify a current delivery mode for the fluid infusion device;
select a matched filter associated with the current delivery mode and the current physical delivery configuration, the matched
filter corresponding to a condition;

correlate the output of the sensing arrangement to an analysis domain variable associated with the matched filter to produce
correlated output values;

apply the matched filter to the correlated output values by calculating a weighted sum of the respective values of the correlated
output values using filter coefficient values of the matched filter as weighting factors for the respective correlated output
values, resulting in a filtered output; and

detect the condition based on the filtered output.

US Pat. No. 9,399,076

OPTICAL SENSOR FOR IN VIVO DETECTION OF ANALYTE

MEDTRONIC MINIMED, INC., ...

1. A sensor for the in vivo detection of glucose, comprising:
components of an assay for glucose, a readout of which is a detectable optical signal which can be interrogated transcutaneously
by external optical means when the sensor is implanted in vivo; and

a shell of biodegradable material encapsulating the assay components whilst allowing an analyte to contact the assay components,
wherein the biodegradable material comprises a co-polymer having hydrophobic units and hydrophilic units, the hydrophilic
units each comprising an ester of polyethylene glycol and a diacid.

US Pat. No. 9,517,304

COORDINATION OF CONTROL COMMANDS AND CONTROLLER DISABLE MESSAGES IN A MEDICAL DEVICE SYSTEM

Medtronic MiniMed, Inc., ...

1. A method of coordinating control commands in a medical device system comprising a medical device that delivers therapy
to a patient, and a plurality of wireless controller devices for the medical device, the method comprising:
wirelessly receiving a control command that is formatted to control a function of the medical device, the control command
originating from an active controller device of the plurality of wireless controller devices;

in response to receiving the control command, wirelessly broadcasting a disable message from the medical device, the disable
message conveying instructions intended to at least partially disable control functions of the plurality of wireless controller
devices;

processing the control command to execute the function; and
wirelessly broadcasting an enable message from the medical device, the enable message conveying instructions intended to override
the effect of the disable message, wherein the enable message is wirelessly broadcast after execution of the function.

US Pat. No. 9,513,104

SYSTEMS AND METHODS FOR ALIGNMENT AND DETECTION OF A CONSUMABLE COMPONENT

Medtronic MiniMed, Inc., ...

1. A method for determining if a consumable component is coupled to a durable component to enable dispersion of a medicine,
comprising:
determining if a signal from an electrical contact coupled to the durable component has changed an electrical state;
comparing the signal to a reference signal from a second electrical component coupled to the durable component;
if the signal is different than the reference signal, sampling a sensor coupled to the durable component to acquire sensor
data indicative of a magnetic field observed by the sensor; and

outputting data that the consumable component is coupled to the durable component if the signal is different than the reference
signal, and the sensor data is within an acceptable range.

US Pat. No. 9,452,256

SMART CONNECTION INTERFACE

Medtronic MiniMed, Inc., ...

1. A connector interface system, comprising:
a reservoir to be received within a reservoir receptacle of an infusion pump device, the reservoir to contain infusion media
to be selectively dispensed from the reservoir when the reservoir is received within the reservoir receptacle;

a connector interface to connect the reservoir with the infusion pump device, the connector interface comprising a cap to
connect to the reservoir to form a reservoir/cap unit;

an infusion set coupled to the cap via a tubing for conveying infusion media dispensed from the reservoir; and
at least one magnetic detectable feature arranged on the cap for detection by at least one sensor element on the infusion
pump device when the reservoir of the reservoir/cap unit is received in the reservoir receptacle of the infusion pump device,

wherein the at least one magnetic detectable feature comprises a magnetic field angle of a magnet that is attached to a housing
of the cap, the magnetic field angle being an angle of orientation of a magnetic field of the magnet relative to a predefined
axis of the cap or the reservoir/cap unit, the magnetic field angle being non-parallel and non-perpendicular to the predefined
axis;

wherein the magnetic field angle of the at least one magnetic detectable feature is at least one detectable parameter that
is associated with one or more characteristics of the cap, the reservoir, a cannula, or a tubing connected between the cap
and the cannula; and

wherein one or more predefined characteristics of the cap, the reservoir, the cannula, or the tubing connected between the
cap and the cannula comprises a type or identity of a manufacturer of the cap, the reservoir, the cannula or the tubing, or
a size of the cap, the reservoir, the cannula or the tubing.

US Pat. No. 9,370,322

MODULAR DOCKING STATION

MEDTRONIC MINIMED, INC., ...

1. A docking station to accommodate a recorder or a transmitter of a monitor system, comprising:
a first dock system including
a dock housing having a dock receiver to interface with a data port for both the recorder and the transmitter;
a logic board being contained within the dock housing, the logic board coupling a memory and a processor to the dock receiver
to enable dock functionality with both the recorder and the transmitter;

a coupling port providing access through the dock housing to a socket coupled to the logic board;
an input/output port to enable power and data transmission from the logic board to a data processor;
a mating arm configured to move between a retracted and extended position, the mating arm defined to fit within the coupling
port, the mating arm being terminated by a plug that couples with the socket; and

a light emitting element on the exterior of the dock housing, the light emitting element coupled to the logic board to provide
visual feedback regarding the status of either the recorder or the transmitter when either are coupled to the dock receiver;

the docking station further including a second dock system, the second dock system being identical to the first dock system,
wherein the first dock system mating arm in the extended position is inserted into the coupling port of the second dock system,
to couple the first dock system and the second dock system into a singular unit.

US Pat. No. 9,364,608

METHOD AND APPARATUS FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP

MEDTRONIC MINIMED, INC., ...

1. A method of detecting an occlusion in an infusion pump having a drive mechanism that includes a motor and one or more drive
train components coupled to a reservoir for delivering fluid from the reservoir through a fluid path into a body of a user,
the method comprising:
taking a series of measurements of a parameter associated with the motor or one of the drive train components;
after each measurement in the series of measurements is taken, performing a comparison between the measurement taken and a
calculated threshold value before taking the next measurement in the series of measurements; and

if the comparison indicates that the measurement taken is less than the calculated threshold value, determining that there
is no occlusion, and delivering said fluid to the user's body; and

wherein, if the comparison indicates that the measurement taken is greater than the calculated threshold value, then an additional
measurement of said parameter is taken, up to a predetermined total number of measurements, and wherein, if the additional
measurement is greater than the calculated threshold value and the predetermined total number of measurements has been reached,
the method further includes: (a) calculating a weighted average of the total number of measurements, (b) comparing the weighted
average to a comparison value, and (c) determining whether an occlusion has occurred in the fluid path of the infusion pump
by determining whether the weighted average is greater than the comparison value.

US Pat. No. 9,163,273

BIOSENSORS AND METHODS FOR MAKING AND USING THEM

Medtronic MiniMed, Inc., ...

1. A composition comprising a porous matrix comprising a lattice of spherical particles having a surface coated with an immobilized
enzyme, wherein:
the porous matrix comprises a micro-porous metal that functions as an electrode in an electrochemical sensor, wherein the
electrode consumes hydrogen peroxide in the electrochemical sensor;

the porous matrix is at least 10, 100, or 1000 microns thick; and
the composition is implantable within a mammal.

US Pat. No. 9,486,575

INFUSION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An infusion device comprising:
a body having a medication delivery channel, the body having an engagement surface with a circular outer border;
an adhesive laminate member mounted to the engagement surface of the body, the adhesive laminate member having an adhesive
layer, a release liner, and a circular outer border that is larger than the circular outer border of the engagement surface
of the body;

a cannula having a portion extending from the body, the cannula having a first external perimeter that is greater than a second
external perimeter of the cannula that is parallel to and below the first external perimeter, the cannula also having a cannula
passageway defined by a cannula passageway wall, the cannula passageway wall including a first portion that cannot be in direct
contact with medication delivered to a patient when the infusion device is used; and

a septum positioned within the medication delivery channel, the septum having a septum top surface that is exposed to open
space, the septum also having a septum bottom surface that is exposed to open space, the septum bottom surface having a bottom-most
portion that is flat and parallel to the engagement surface;

the infusion device being configured so that a portion of the infusion device will be above a patient's skin when the infusion
device is used.

US Pat. No. 9,388,805

MEDICATION PUMP TEST DEVICE AND METHOD OF USE

MEDTRONIC MINIMED, INC., ...

1. A test device for use with a medication pump and a depth indicator, the medication pump defining a reservoir compartment
having an open end with an open end diameter, the depth indicator having a fixed portion and a slide spindle slideably connected
to the fixed portion, the test device comprising:
an external body portion having an external diameter greater than the open end diameter, the external body portion defining
a depth indicator recess operable to receive the fixed portion of the depth indicator;

an internal body portion attached to the external body portion, the internal body portion having an external diameter less
than the open end diameter and defining a slide spindle passage operable to allow free axial movement of the slide spindle
of the depth indicator, a junction of the internal body portion and the external body portion defining an external contact
portion;

wherein the depth indicator recess and the slide spindle passage are in communication along a central axis of the test device,
and

the test device maintains the fixed portion of the depth indicator at a fixed axial position along the central axis relative
to the medication pump when the fixed portion of the depth indicator is seated in the depth indicator recess, the external
contact portion contacts the medication pump, and the internal body portion is seated in the open end of the reservoir compartment.

US Pat. No. 9,848,805

BIOSTABLE GLUCOSE PERMEABLE POLYMER

Medtronic MiniMed, Inc., ...

1. A glucose sensing system comprising:
a tubular housing having a first end and a second end, wherein:the tubular housing comprises a polymeric composition formed by combining:
an isocyanate;
a polypropylene glycol-block-polyethylene glycol-block-polypropylene glycol having an average molecular weight (Mr) of from about 600 to about 1200 Daltons; and

a terephthalate; andthe polymeric composition has a glucose permeability of at least 1×10?8 cm2/s at 37° C. in phosphate buffered saline.

US Pat. No. 9,750,878

CLOSED-LOOP CONTROL OF GLUCOSE ACCORDING TO A PREDICTED BLOOD GLUCOSE TRAJECTORY

MEDTRONIC MINIMED, INC., ...

1. A method comprising:
predicting a trajectory of a blood glucose level of a patient based, at least in part, on past observations of said blood
glucose level;

determining a cost expression based, at least in part, on said predicted trajectory,
wherein said cost expression is based, at least in part, on a first duration of time that said trajectory is predicted to
be under a lower bound blood glucose limit of a target blood glucose concentration range, and is also based, at least in part,
on a second duration of time that said trajectory is predicted to be above an upper bound blood glucose limit of said target
blood glucose concentration range, the first duration of time corresponding to a predicted hypoglycemic time period, and the
second duration of time corresponding to a predicted hyperglycemic time period,

wherein said cost expression is further based, at least in part, on a degree or extent to which said predicted blood glucose
level is to extend outside of the target blood glucose concentration range under the lower bound blood glucose limit during
said first duration of time, and

wherein said cost expression is further based, at least in part, on a degree or extent to which said predicted blood glucose
level is to extend outside of the target blood glucose concentration range above the upper bound blood glucose limit during
said second duration of time; and

affecting at least one future command to at least one infusion pump so as to shorten the predicted hypoglycemic time period
and to shorten the predicted hyperglycemic time period according to said cost expression.

US Pat. No. 9,492,111

METHODS AND MATERIALS FOR STABILIZING ANALYTE SENSORS

Medtronic MiniMed, Inc., ...

1. A sensor system comprising:
a sensor having a chemically reactive surface that reacts with an analyte to be sensed; and
a cannula comprising:
a substantially cylindrical housing that surrounds the sensor;
at least one aperture disposed in the housing that allows the analyte to diffuse therethrough so as to contact the chemically
reactive surface;

an end that extends beyond an end of the sensor;
an accessory material provided in proximity to the chemically reactive surface, wherein:
the accessory material fills the at least one aperture of the cannula;
the accessory material is disposed in the aperture such that a surface of the accessory material is substantially flush with
a surface of the cannula; and

the sensor system is adapted to contact a tissue such that the accessory material is configured to contact and modify a biological
response of the tissue.

US Pat. No. 9,295,776

RESERVOIR PLUNGER HEAD SYSTEMS AND METHODS

Medtronic MiniMed, Inc., ...

1. A system for transferring fluidic media, the system comprising:
a reservoir body having an interior volume for containing fluidic media and an opening;
a plunger head moveable in an axial direction within the reservoir body;
a plunger arm operatively connected to the plunger head, the plunger arm having an arm portion extending out of the opening
of the reservoir body for operatively engaging a drive member configured to move the plunger arm and the plunger head relative
to the reservoir body when the arm portion is operatively engaged to the drive member;

a reservoir cover covering at least a portion of the opening of the reservoir body; and
a casing concentrically surrounding the plunger arm for supporting or aligning the plunger arm, wherein the casing is fixed
to the reservoir cover so as to extend from the reservoir cover along the axial direction to allow the plunger arm to move
in the axial direction relative to the casino and the reservoir body to move the plunger head in the axial direction within
the reservoir body.

US Pat. No. 9,289,168

SYSTEM AND/OR METHOD FOR GLUCOSE SENSOR CALIBRATION

Medtronic Minimed, Inc., ...

1. A method comprising:
obtaining samples of an electrical signal generated by a sensor, said samples having sample values responsive to a blood-glucose
concentration in a patient;

obtaining blood glucose reference measurement values responsive to said blood-glucose concentration;
pairing at least some of the sample values with temporally associated blood glucose reference measurement values;
for at least one of said paired sample values, weighting said paired sample value based, at least in part, on a measure of
statistical dispersion of said electrical signal, said measure of statistical dispersion of said electrical signal being a
function of a blood glucose reference measurement value paired with said sample value;

determining one or more parameters of an estimator of said blood-glucose concentration based, at least in part, on said weighted
paired sample values; and

controlling a pump to infuse a substance to said patient based, at least in part, on said determined one or more parameters
of said estimator of said blood-glucose concentration.

US Pat. No. 9,943,332

INSERTION DEVICE SYSTEMS AND METHODS

Medtronic MiniMed, Inc., ...

1. An insertion system, the insertion system comprising:a base having a device housing, the base adapted to be carried by a patient, the device housing being configured to engage with an actuation device;
a carrier body supported by the device housing for movement at least between a retracted position and an advanced position, the carrier body for supporting a piercing member in a position orientated for insertion through skin of the patient upon movement of the carrier body from the retracted position to the advanced position, the carrier body being configured to operatively engage with a moveable carrier body of the actuation device so that the carrier body of the device housing is moved by the carrier body of the actuation device at least between the retracted position and the advanced position; and
a magnet or a magnetically attractive element attached to the carrier body of the device housing, for magnetic interaction with another magnet or magnetically attractive element on the carrier body of the actuation device, to magnetically connect the carrier body of the device housing with the carrier body of the actuation device, and to apply an attractive force between the carrier body of the device housing and the carrier body of the actuation device so that the carrier body of the device housing is moved from the advanced position to the retracted position as the carrier body of the actuation device is moved from the advanced position to the retracted position.

US Pat. No. 9,636,456

SYSTEM FOR PROVIDING BLOOD GLUCOSE MEASUREMENTS TO AN INFUSION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An infusion system for infusing insulin into a body of a user, the infusion system comprising:
a sensing device including:
a sensor configured to continuously measure glucose levels in the user;
a sensing device processor coupled to the sensor and configured to process sensor values indicative of the glucose levels
in the user measured by the sensor; and

a sensing device transmitter coupled to the sensing device processor and configured to transmit a communication including
the sensor values indicative of the glucose levels in the user measured by the sensor;

an external hand-held characteristic determining device including:
a determining device housing configured to be carried by the user;
a receptacle coupled to the determining device housing and configured to receive and test a blood sample from the user to
obtain a blood glucose measurement;

a determining device processor contained in the determining device housing and coupled to the receptacle and configured to
process the obtained blood glucose measurement; and

a determining device transmitter contained in the determining device housing and coupled to the determining device processor
and configured to transmit a communication including the obtained blood glucose measurement; and

an infusion device including:
an infusion device housing configured to be carried by a user;
a drive mechanism contained in the infusion device housing and operatively coupled with a reservoir containing insulin for
infusing the insulin into the body of the user;

an infusion device receiver contained in the infusion device housing and configured to receive the communication from the
sensing device transmitter and the communication from the determining device transmitter;

an infusion device processor contained in the infusion device housing and coupled to the infusion device receiver and configured
to process the sensor values received from the sensing device transmitter and the obtained blood glucose measurement received
from the determining device transmitter;

an infusion device indicator coupled to the infusion device processor and configured to indicate the sensor values and the
blood glucose measurement; and

a bolus estimator used in conjunction with the infusion device processor for calculating an estimated amount of insulin to
be infused into the body of the user based upon the obtained blood glucose measurement received from the determining device
transmitter and a target blood glucose level for the user, wherein the infusion device processor determines an amount of time
that has elapsed since the obtained glucose measurement was received from the determining device transmitter, and prevents
the bolus estimator from calculating the estimated amount of insulin to be infused based upon the obtained blood glucose measurement
if the elapsed amount of time exceeds a predetermined amount of time, and causes the bolus estimator to calculate the estimated
amount of insulin to be infused based upon the obtained blood glucose measurement if the elapsed amount of time does not exceed
the predetermined amount of time, and wherein the infusion device indicator further indicates when the estimated amount of
insulin to be infused has been calculated.

US Pat. No. 9,480,796

SYSTEM AND METHOD FOR PROVIDING CLOSED LOOP INFUSION FORMULATION DELIVERY

MEDTRONIC MINIMED, INC., ...

1. An insulin formulation delivery system, comprising:
an infusion device that delivers an amount of insulin formulation in accordance with a plurality of components, including
a proportional component, a derivative component, and a basal rate component that is programmable; and

a controller that receives a sensor signal representative of a sensed blood glucose level from a sensor at predefined timed
intervals, determines a rate of change in the sensed blood glucose level that includes a trend term over time, compares the
sensed blood glucose level in the sensor signal to a predefined blood glucose level threshold, and generates commands that
are communicated to the infusion device including a command to disable delivery of the basal rate component if the trend term
is falling over time and the sensed blood glucose level crosses the predefined blood glucose level threshold.

US Pat. No. 9,379,652

MOTOR HEALTH MONITORING AND MEDICAL DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. A system comprising:
a stepper motor having a rotor and sets of windings;
a sensor to detect incremental rotations of the rotor;
a modulation module to generate a modulated voltage oscillating between a first voltage and a second voltage, the modulated
voltage being equal to the first voltage for a percentage of a time interval, the percentage corresponding to a duty cycle;

a motor driver module coupled between the modulation module and the stepper motor to apply the modulated voltage to one or
more of the sets of windings; and

a control module coupled to the sensor, the modulation module, and the motor driver module to:
operate the motor driver module to sequentially apply the modulated voltage to the one or more of the sets of windings in
a particular order to produce a commanded number of motor steps of rotation by the rotor;

obtain a measured number of the incremental rotations from the sensor after the stepper motor is operated to provide the commanded
number of motor steps;

increase the duty cycle for the modulated voltage in response to a difference between an expected number of incremental rotations
corresponding to the commanded number of motor steps and the measured number of the incremental rotations; and

detect a degradation condition based on the duty cycle.

US Pat. No. 9,344,024

OCCLUSION DETECTION USING PULSE-WIDTH MODULATION AND MEDICAL DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. A method of detecting an occlusion in a fluid path of an infusion device, the method comprising:
applying a modulated voltage to a stepper motor to produce a commanded number of motor steps of rotation of a rotor of the
stepper motor, the rotation of the rotor resulting in delivery of fluid via the fluid path;

determining an expected number of incremental rotations expected to be detected by a sensor coupled to the stepper motor in
response to applying the modulated voltage to the stepper motor to produce the commanded number of motor steps based on the
commanded number of motor steps;

obtaining a measured number of incremental rotations of the rotor from the sensor in response to applying the modulated voltage
to the stepper motor to produce the commanded number of motor steps;

adjusting a duty cycle of the modulated voltage to achieve the commanded number of motor steps in response to a difference
between the expected number and the measured number; and

identifying an occlusion condition based on the duty cycle.

US Pat. No. 9,101,305

GLUCOSE SENSOR PRODUCT AND RELATED MANUFACTURING AND PACKAGING METHODS

Medtronic MiniMed, Inc., ...

1. A method of manufacturing a medical device package, the method comprising:
fabricating a medical device assembly;
placing the medical device assembly into a package tray;
sealing the medical device assembly inside the package tray with a gas-permeable sealing material, resulting in a sealed package
tray; and

sterilizing the medical device assembly inside the sealed package tray, wherein the sealing material maintains sterility of
the medical device assembly while allowing volatile substances to vent from inside the sealed package tray to outside the
sealed package tray wherein the medical device assembly comprises an electrochemical sensor with glucose oxidase enzyme; and
the sealing material vents volatile substances that would otherwise degrade the glucose oxidase enzyme.

US Pat. No. 9,770,553

MONITORING THE OPERATING HEALTH OF A FORCE SENSOR IN A FLUID INFUSION DEVICE

MEDTRONIC MINIMED, INC., ...

1. A device for delivering fluid to a user, the device comprising:
a housing;
a drive motor assembly in the housing to regulate delivery of fluid by actuating a piston of a fluid reservoir;
a force sensor associated with the drive motor assembly to generate output levels in response to force imparted thereto, the
force sensor located proximal to the drive motor assembly and between a proximal end of the drive motor assembly and a proximal
end of the housing; and

an electronics module coupled to the force sensor to process the output levels to determine operating health of the force
sensor, and the electronics module:

determines a rewind force measurement that indicates a rewind force imparted to the force sensor during a rewind operation;
compares the rewind force measurement to a first force measurement threshold; and
based on the comparison, initiates a corrective action based on the rewind force measurement being less than the first force
measurement threshold.

US Pat. No. 9,755,452

POWER CONTROL TECHNIQUES FOR AN ELECTRONIC DEVICE

Medtronic MiniMed, Inc., ...

1. A power distribution system for a portable electronic device, the power distribution system comprising:
a first voltage rail to provide operating voltage for basic functions of the electronic device;
a second voltage rail to provide operating voltage for high power functions of the electronic device;
a primary battery coupled in a selectable manner to the first voltage rail and the second voltage rail;
a secondary battery coupled in a selectable manner to the first voltage rail and the second voltage rail;
a selection architecture coupled to the first voltage rail, the second voltage rail, the primary battery, and the secondary
battery;

a control module to regulate operation of the selection architecture in accordance with:
a first power phase during which the primary battery is coupled to the first voltage rail and to the second voltage rail to
provide energy for the basic functions and the high power functions;

a second power phase during which the primary battery is coupled to the first voltage rail to provide energy for the basic
functions, and during which the secondary battery is coupled to the second voltage rail to provide energy for the high power
functions; and

a third power phase during which the secondary battery is coupled to the first voltage rail and to the second voltage rail
to provide energy for the basic functions and the high power functions; and

a voltage converter to convert an output voltage of the primary battery to a main supply voltage for the electronic device,
wherein the control module monitors the main supply voltage during operation of the electronic device and arranges the selection
architecture in accordance with the first power phase, the second power phase, or the third power phase based on the monitored
main supply voltage.

US Pat. No. 9,636,453

ADVANCE DIAGNOSIS OF INFUSION DEVICE OPERATING MODE VIABILITY

Medtronic MiniMed, Inc., ...

1. An infusion device comprising:
a user interface;
a memory to maintain status information pertaining to the infusion device;
a motor operable to deliver fluid to a body of a user, the fluid influencing a physiological condition of the user; and
a control system coupled to the motor, the memory, and the user interface to:
operate the motor in a first instance to deliver the fluid in accordance with a closed-loop operating mode to regulate the
physiological condition of the user to a target value using one or more control parameters, the one or more control parameters
comprising one or more proportional-integral-derivative (PID) gain coefficients;

store operational information pertaining to the first instance of the closed-loop operating mode in the memory;
determine an expected start time for a subsequent instance of the closed-loop operating mode based at least in part on the
operational information;

determine an expected duration for the subsequent instance of the closed-loop operating mode based at least in part on the
operational information;

determine a diagnosis time prior to the expected start time;
at the diagnosis time prior to the expected start time, automatically determine viability of entering the subsequent instance
of the closed-loop operating mode at the expected start time for the expected duration based at least in part on the status
information by performing an algorithmic diagnostic check to determine availability of the closed-loop operating mode at the
expected start time in the future for the subsequent instance of the closed-loop operating mode, wherein the algorithmic diagnostic
check comprises determining whether the one or more control parameters can be calculated at the expected start time; and

automatically provide, via the user interface, a notification indicative of a recommended action based at least in part on
the viability.

US Pat. No. 9,526,834

SAFEGUARDING MEASURES FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM

Medtronic MiniMed, Inc., ...

1. A processor-implemented method of controlling an insulin infusion device for a user, the insulin infusion device comprising
an insulin reservoir for insulin to be delivered from the insulin infusion device to a body of a user, and further comprising
a processor architecture comprising at least one processor device, the method comprising:
operating the processor architecture to obtain a current insulin on board (IOB) value that represents an estimate of active
insulin in the body of the user;

calculating, by the processor architecture, an IOB rate based at least in part on the obtained current IOB value, wherein
the IOB rate represents an amount of active insulin accumulated from manual boluses in the body of the user per unit of time;

determining, by the processor architecture, an adjusted insulin infusion rate based at least in part on the calculated IOB
rate and an uncompensated insulin infusion rate;

selecting, by the processor architecture, a final insulin infusion rate for the insulin infusion device, wherein the selecting
selects either the determined adjusted insulin infusion rate, the uncompensated insulin infusion rate, or a current basal
rate as the final insulin infusion rate, wherein selecting the final insulin infusion rate is in accordance with either expression
FinalRate(n)=max(Basal; AdjustedRate(n)) when PIDRate>Basal, or expression FinalRate(n)=PIDRate(n) when PIDRate?Basal, and
wherein FinalRate(n) is the selected final insulin infusion rate, Basal is the current basal rate, AdjustedRate(n) is the
determined adjusted insulin infusion rate, and PIDRate(n) is the uncompensated insulin infusion rate; and

operating the insulin infusion device in a closed-loop mode to continuously deliver insulin from the insulin reservoir to
the body of the user in accordance with the final insulin infusion rate that is selected, wherein the final insulin infusion
rate represents an amount of insulin to be delivered per unit of time.

US Pat. No. 9,452,255

SMART CONNECTION INTERFACE

Medtronic MiniMed, Inc., ...

1. A connector interface system, comprising:
a cap to connect to a reservoir to form a reservoir/cap unit for installation into an infusion pump device; and
at least one magnetic detectable feature arranged on the cap for detection by at least one sensor element on the infusion
pump device when the reservoir of the reservoir/cap unit is received in a reservoir receptacle of the infusion pump device,

wherein the at least one magnetic detectable feature comprises a magnetic field angle of a magnet that is attached to a housing
of the cap, the magnetic field angle being an angle of orientation of a magnetic field of the magnet relative to a predefined
axis of the cap or the reservoir/cap unit, the magnetic field angle being non-parallel and non-perpendicular to the predefined
axis;

wherein the magnetic field angle of the at least one magnetic detectable feature is at least one detectable parameter that
is associated with one or more characteristics of the cap, the reservoir, a cannula, or a tubing connected between the cap
and the cannula; and

wherein one or more predefined characteristics of the cap, the reservoir, the cannula, or the tubing connected between the
cap and the cannula comprises a type or identity of a manufacturer of the cap, the reservoir, the cannula or the tubing, or
a size of the cap, the reservoir, the cannula or the tubing.

US Pat. No. 9,421,287

METHODS FOR MAKING AN AQUEOUS RADIATION PROTECTING FORMULATION

Medtronic Minimed, Inc., ...

1. A method of inhibiting damage to a saccharide sensor that can result from a radiation sterilization process, the method
comprising combining the saccharide sensor with an aqueous radioprotectant formulation during the sterilization process, wherein:
the saccharide sensor comprises a saccharide binding polypeptide;
the aqueous radioprotectant formulation comprises an antioxidant compound; and
performing the sterilization process under conditions wherein the antioxidant reacts with a free radical compound produced
during the radiation sterilization process, wherein the free radical compound can react with and damage the saccharide binding
polypeptide.

US Pat. No. 9,415,157

EXTERNAL INFUSION DEVICE WITH REMOTE PROGRAMMING, BOLUS ESTIMATOR AND/OR VIBRATION ALARM CAPABILITIES

MEDTRONIC MINIMED, INC., ...

1. An external infusion device for infusing insulin into a body of a user from a reservoir, the external infusion device comprising:
a device housing for use on an exterior of the body and sized to be held in a hand of the user;
a drive mechanism at least partially contained within the housing and operatively coupled to the reservoir for infusing insulin
into the body of the user from the reservoir;

a processor contained within the housing and coupled to the drive mechanism;
a memory contained within the housing and coupled to the processor for storing a target glucose level, an insulin sensitivity,
and a carbohydrate ratio of the user;

a display device contained within the housing and coupled to the processor for displaying information to the user, wherein
the display device includes a touch screen input device for enabling the user to input a current glucose level of the user
and carbohydrates being consumed by the user; and

a bolus estimator contained within the housing and used in conjunction with the processor and the display device including
the touch screen input device to calculate a bolus of insulin to be infused based upon the current glucose level, the target
glucose level, the insulin sensitivity, the carbohydrates being consumed, and the carbohydrate ratio, wherein the calculated
bolus of insulin to be infused is provided to the user on the display device.

US Pat. No. 9,205,191

AUTOMATED FILLING SYSTEMS AND METHODS

Medtronic MiniMed, Inc., ...

1. A system for transferring fluidic media, comprising:
a holding unit for holding a reservoir, the holding unit configured such that a plunger arm that is connected to a plunger
head that is within the reservoir is moveable when the holding unit is holding the reservoir and the reservoir is being filled
with fluidic media;

a vibrator for vibrating the holding unit so as to vibrate the reservoir; and
a transfer guard for transferring fluidic media from a vial to the reservoir when the holding, unit is holding the reservoir,
the transfer guard including a first end for at least partially surround in a port of the reservoir when a needle of the transfer
guard pierces a septum in the port of the reservoir.

US Pat. No. 9,494,147

RESERVOIR FILLING SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of making a system for transferring fluidic media, the method comprising:
filling an interior volume of a reservoir body with fluidic media;
placing a plunger head within the reservoir body, the plunger head being moveable in an axial direction within the reservoir
body;

connecting a plunger arm to the plunger head, the plunger arm configured to selectively engage and disengage with a drive
member, the plunger arm for moving the plunger head in the axial direction of the reservoir body when the plunger arm is engaged
with and driven by the drive member, the plunger arm configured to be carried with the reservoir body away from the drive
member when the plunger arm is disengaged from the drive member; and

after filling the interior volume of the reservoir body, connecting a casing to the reservoir body to cover at least a portion
of the plunger arm and to allow the plunger arm to move in the axial direction relative to the reservoir body, the casing
configured to be carried with the reservoir body away from the drive member when the casing is connected to the reservoir
body and the plunger arm is disengaged and separated from the drive member.

US Pat. No. 9,493,807

FOLDOVER SENSORS AND METHODS FOR MAKING AND USING THEM

Medtronic Minimed, Inc., ...

1. An analyte sensor apparatus comprising:
a base substrate comprising a planar sheet of a flexible material, wherein the base substrate is folded to form a fixed bend;
a plurality of working electrodes, a plurality of counter electrodes and a plurality of reference electrodes disposed upon
a first surface of the base substrate;

a plurality of contact pads disposed upon the first surface of the base substrate;
a plurality of electrical conduits disposed upon the first surface of the base substrate, wherein the plurality of electrical
conduits are adapted to transmit electrical signals between the plurality of working electrodes, the plurality or counter
electrodes or the plurality of reference electrodes and the plurality of contact pads;

an analyte sensing layer disposed over at least one of the plurality of working electrodes, wherein the analyte sensing layer
detectably alters the electrical current at the at least one of the plurality of working electrodes in the presence of an
analyte; and

an analyte modulating layer disposed over the analyte sensing layer, wherein the analyte modulating layer modulates the diffusion
of the analyte therethrough;
wherein:
the base substrate comprises the fixed bend so as to form a configuration characterized in that:
at least one of the plurality of working electrodes, the plurality of counter electrodes or the plurality of reference electrodes
is disposed on a first side of the fixed bend; and

at least one of the plurality of working electrodes, the plurality of counter electrodes or the plurality of reference electrodes
is disposed on a second side of the fixed bend and

the plurality of contact pads are disposed on the first side of the fixed bend.

US Pat. No. 9,445,757

GLYCEMIC HEALTH METRIC DETERMINATION AND APPLICATION

Medtronic Minimed, Inc., ...

1. A method using one or more indicators of glycemic health in a patient to balance one or more of hypoglycemic or hyperglycemic
tendencies for the patient, the method comprising:
at a special purpose computing apparatus, computing a profile of a blood glucose concentration of the patient based, at least
in part, on observations of the blood glucose concentration collected at a blood glucose monitoring device;

applying a cost or loss function to the computed profile to compute a metric for balancing short-term and long-term risks
associated with a therapy, the metric representative of the glycemic health of the patient, the cost or loss function being
based, at least in part, on a log-square metric, wherein the metric is also based, at least in part, on a parameter selected
to balance one or more Spearman rank coefficients with one or more hypoglycemic-based metrics and one or more hyperglycemic-based
metrics; and

altering an insulin therapy applied to the patient by an infusion device, the altered insulin therapy determined based, at
least in part, on the computed metric, wherein the altered insulin therapy is also based, at least in part, on a target blood
glucose concentration level or target blood glucose range that has been adjusted upward or downward based, at least in part,
on an indication by the computed metric of whether the patient is tending towards hypoglycemia or tending towards hyperglycemia.

US Pat. No. 9,440,025

APPARATUS AND METHOD FOR CONTROLLING INSULIN INFUSION WITH STATE VARIABLE FEEDBACK

MEDTRONIC MINIMED, INC., ...

1. An apparatus for infusing insulin into a body of a user, the apparatus comprising:
a housing;
a pump inside the housing for delivering insulin into the body of the user; and
at least one controller to control delivery of the insulin from the housing by the pump, wherein the at least one controller:
controls delivery of a basal amount of insulin to the body of the user at a predetermined basal rate;
determines at least one state variable, said at least one state variable being at least one of subcutaneous insulin concentration,
plasma insulin concentration, and insulin effect;

determines, based on the at least one state variable, an additional amount of insulin to be delivered to the body of the user;
controls delivery of the determined additional amount of insulin to the body of the user; and
reduces the basal rate by the additional amount of insulin.

US Pat. No. 9,433,733

METHODS AND APPARATUSES FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP

MEDTRONIC MINIMED, INC, ...

1. A method of detecting an occlusion in an infusion pump having a drive mechanism that includes a motor and one or more drive
train components coupled to a reservoir for infusing fluid from the reservoir into a body of a user, the method comprising:
(a) measuring a plurality of respective values of at least two different parameters associated with the motor or one of the
drive train components;

(b) calculating a respective average value based on said plurality of measured values for each of the at least two different
parameters;

(c) adding said respective average values to obtain a combined value; and
(d) determining whether an occlusion has occurred in the fluid path of the infusion pu p by using the combined value.

US Pat. No. 9,375,537

THERAPEUTIC AGENT INJECTION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An injection device for delivering a therapeutic agent to a patient, the injection device comprising:
a body having a patient face and a port face opposite the patient face, the port face having an introducer port including
an introducer channel and an injection port including an injection channel, the injection channel defining an injection axis;

a delivery tube for subcutaneous delivery of the therapeutic agent to the patient, the delivery tube projecting from and being
generally perpendicular to the patient face, the delivery tube defining an introducer axis and being in fluid communication
with the introducer port;

a patch attached to the patient face and operable to adhesively attach to the patient;
wherein the injection port is defined to accommodate a sensor; and
further comprising an injection adapter assembly connectable to the introducer port, the injection adapter assembly being
operable to receive a needleless pen injector.

US Pat. No. 9,333,292

MECHANICALLY ACTUATED FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A fluid infusion device for delivery of a medication fluid to the body of a user, the fluid infusion device comprising:
a housing;
a fluid reservoir for the medication fluid, wherein the fluid reservoir is located in the housing, and wherein the medication
fluid in the fluid reservoir is maintained under positive pressure;

a valve assembly located in the housing and coupled to the fluid reservoir;
a dosing mechanism located in the housing and coupled to the fluid reservoir via the valve assembly, the dosing mechanism
comprising an adjustable fluid chamber that defines a user-selectable dosage volume, and the dosing mechanism comprising a
mechanical actuator; and

a fluid conduit coupled to the dosing mechanism via the valve assembly, wherein at least a portion of the fluid conduit is
external to the housing when the fluid infusion device is deployed for operation; wherein:

application of an actuation force to the mechanical actuator initiates a fluid delivery operation;
removal of the actuation force from the mechanical actuator initiates a refill operation;
during the fluid delivery operation, the valve assembly allows the medication fluid to flow from the adjustable fluid chamber
into the fluid conduit for delivery to the body of the patient, while inhibiting flow of the medication fluid from the adjustable
fluid chamber into the fluid reservoir; and

during the refill operation, the valve assembly allows the medication fluid to flow from the fluid reservoir into the adjustable
fluid chamber, while inhibiting flow of the medication fluid from the fluid reservoir into the fluid conduit.

US Pat. No. 9,272,125

SEALING ASSEMBLY FOR A FLUID RESERVOIR OF A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A sealing assembly for a fluid infusion device, the sealing assembly comprising:
a durable housing that receives and mates with a removable fluid reservoir having a fluid delivery port extending from the
fluid reservoir and having a funnel-shaped interior defined therein, wherein the durable housing houses the removable fluid
reservoir and retains the removable fluid reservoir in a particular position and orientation;

a base plate having an adhesive layer of material to adhere the base plate to skin of a patient, and having a coupling structure
to removably couple the base plate to the durable housing of the fluid infusion device;

a reservoir port receptacle integrally formed with the base plate to receive and engage the fluid delivery port of the fluid
reservoir in the particular position and orientation when the durable housing is coupled to the base plate, wherein the fluid
delivery port of the fluid reservoir resides within the reservoir port receptacle when the durable housing is coupled to the
base plate;

a hollow fluid delivery needle coupled to the base plate and extending within the reservoir port receptacle to provide a fluid
flow path from the fluid reservoir to a user of the fluid infusion device when the durable housing is coupled to the base
plate; and

a sealing element coupled to the base plate and overlying at least a portion of the hollow fluid delivery needle, the sealing
element comprising:

a base section;
a tip section extending from the base section, the tip section shaped to enter and seal with the funnel-shaped interior of
the fluid delivery port when the durable housing is coupled to the base plate;

a retractable body section between the base section and the tip section;
a needle cavity formed in the retractable body section and continuing through the base section to define a needle opening
in the base section, the needle cavity sized to receive the hollow fluid delivery needle; and

a self-sealing slit formed in the tip section to accommodate the hollow fluid delivery needle when the sealing element is
in a retracted position caused by coupling of the durable housing with the base plate.

US Pat. No. 9,597,461

INJECTION APPARATUS AND SPECIAL NEEDLE FOR MAKING AN INJECTION AT A PREDETERMINED DEPTH IN THE SKIN

MEDTRONIC MINIMED, INC., ...

1. An injection apparatus for making an injection at a predetermined depth in skin, comprising:
a skin positioning member for positioning a patch of skin within an area of skin to hold the patch of skin in a defined position;
an injection needle comprising a tip, at least one bevel and a heel together forming a point at a distal end thereof, and
a shaft portion immediately proximal of said heel having a longitudinal axis, including a lumen extending along the longitudinal
axis, wherein the at least one bevel is formed between said tip and said heel such that a lumen opening is defined from the
tip to a proximal end of the lumen opening located distal of the heel;

and an injection needle movement guide proximate the injection needle to guide said injection needle for movement from a parking
position above said skin positioning member to an injection position in which the distal end of the needle lies at a predetermined
distance below said skin positioning member;
wherein:
a length of the lumen opening of the needle from the tip of the needle to the proximal end of the lumen opening is in a range
from 5 to 15 times an outer diameter of the shaft of the needle and the length of the lumen opening of the needle is measured
parallel to the longitudinal axis of the needle;

wherein at least a part of the point of the injection needle is formed substantially parallel to the longitudinal axis of
the needle.

US Pat. No. 9,598,210

RESERVOIR PRESSURE EQUALIZATION SYSTEMS AND METHODS

Medtronic MiniMed, Inc., ...

11. A fluid delivery system comprising:
a fluid reservoir having a neck and a fluid vent formed in the neck to accommodate expulsion of pressurized fluidic media
from the fluid reservoir; and

a base assembly having a proximal section, a distal section, and an intermediate section between the proximal section and
the distal section, wherein the base assembly comprises:

a valve movable between an extended position and a retracted position, wherein the valve is located in the proximal section,
intermediate section and distal section when in the extended position, and wherein the valve is removed from the intermediate
section and distal section when in the retracted position;

a fluid delivery port in the intermediate section;
a recess to accommodate the neck in an inserted state during which the neck is received in the distal section and the intermediate
section; and

a proximal sealing member at a proximal interface between the proximal section and the intermediate section to form a fluid
tight seal with the valve; and

a distal sealing member at a distal interface between the intermediate section and the distal section to form a fluid tight
seal with the neck in the inserted state and to form a fluid tight seal with the valve in the extended position;

wherein, in the inserted state, fluid communication is opened between the fluid vent and the fluid delivery port within the
intermediate section.

US Pat. No. 9,421,321

CONNECTION AND ALIGNMENT SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A medical device for treating a user, the medical device comprising:
a first housing portion adapted to be carried by a user;
a second housing portion configured to be selectively operatively engaged with and disengaged from the first housing portion;
a plurality of electrical contacts provided on at least one of the first housing portion and the second housing portion, the
plurality of electrical contacts including a set of main electrical contacts and at least one other electrical contact;

a shorting mechanism provided on the other of the first housing portion and the second housing portion, the shorting mechanism
for interacting with the set of main electrical contacts;

a magnetic source having at least one of a certain magnetic field and a certain magnetic strength provided on at least one
of the first housing portion and the second housing portion; and

electronic circuitry configured to provide a first signal when the first housing portion and the second housing portion are
brought together, the shorting mechanism interacts with the set of main electrical contacts of the plurality of electrical
contacts, and a sensor detects at least one of the certain magnetic field and the certain magnetic strength of the magnetic
source;

the electronic circuitry further configured to provide a second signal when the first housing portion and the second housing
portion are brought together and at least one of the shorting mechanism interacts with the at least one other electrical contact
of the plurality of electrical contacts and the sensor detects at least one of a magnetic field different from the certain
magnetic field and a magnetic strength different from the certain magnetic strength of the magnetic source.

US Pat. No. 9,399,096

AUTOMATIC CLOSED-LOOP CONTROL ADJUSTMENTS AND INFUSION SYSTEMS INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. An infusion system comprising:
a motor operable to deliver fluid to a user, delivery of the fluid influencing a first condition of the user;
a sensing arrangement to obtain a measured value indicative of the first condition of the user;
a heart rate sensing arrangement to obtain heart rate measurement data for the user; and
a control system coupled to the motor, the heart rate sensing arrangement, and the sensing arrangement to:
determine a heart rate variability metric for the user based on a spectral analysis of the heart rate measurement data;
detect a second condition of the user that is likely to influence a response to the fluid in a body of the user based on the
heart rate measurement data when a measured heart rate for the user is greater than a first threshold value and the heart
rate variability metric is less than a second threshold value;

classify the second condition as exercise; and
after classifying the second condition as exercise:
adjust control information for operating the motor, resulting in adjusted control information; and
operate the motor to deliver the fluid to the user based at least in part on the adjusted control information and a difference
between a target value for the first condition of the user and the measured value, wherein:

the adjusted control information comprises a decreased gain coefficient; and
the control system determines the decreased gain coefficient by estimating an amount of energy expenditure during the exercise,
calculating a change in glycemic level for the user based on the amount of energy expenditure, determining an equivalent insulin
amount based on the change in glycemic level, and determining an adjusted proportional gain coefficient based on a first difference
between a daily insulin requirement for the user and the equivalent insulin amount.

US Pat. No. 9,179,870

METHOD OF MAKING A SENSOR WITH LAYERED ELECTRODES

MEDTRONIC MINIMED, INC., ...

1. A method of making a flexible analyte sensor, the method comprising:
providing a base layer;
forming a first electrode layer on the base layer, wherein the first electrode layer includes a first electrode;
forming a first insulative layer on the first electrode layer;
forming a second electrode layer on the first insulative layer, wherein the second electrode layer includes a second electrode;
and

forming a second insulative layer on the second electrode layer, wherein the first and second electrodes are in a staggered
configuration.

US Pat. No. 9,782,540

SAFETY LIMITS FOR CLOSED-LOOP INFUSION PUMP CONTROL

Medtronic MiniMed, Inc., ...

1. An infusion pump system for delivering an infusion media to a user, the infusion pump system comprising:
a sensing device to monitor glucose levels in the user;
a user interface for receiving user input relating to a food ingestation event;
a pump for delivering an infusion media to a user;
a computing element operatively connected to the pump and configured to adjust delivery of the infusion media dependent at
least in part on glucose levels monitored by the sensing device and at least in part on user input received through the user
interface;

the computing element configured to adjust delivery of the infusion media by the pump, based at least in part on an initial
user input received by the user interface, relating to the food ingestation event,

the computing element configured to further adjust delivery of the infusion media by the pump, based at least in part on an
updated user input received by the user interface, relating to the food ingestation event.

US Pat. No. 9,717,848

DATA DERIVED PRE-BOLUS DELIVERY

Medtronic MiniMed, Inc., ...

1. A medical therapy system to deliver a pre-bolus volume of medicant, the medical therapy system comprising:
an infusion pump having a case, the case containing a processor, memory, a drive mechanism, a reservoir, and communication
hardware;

the infusion pump further including a global positioning system (GPS) receiver to determine GPS coordinates of the infusion
pump, the GPS receiver being coupled to the processor, the processor executing stored program instructions to provide notification
for confirmation to deliver a pre-bolus volume from the reservoir when the GPS coordinates of the infusion pump are within
a specified proximity of GPS coordinates of a known location.

US Pat. No. 9,649,058

METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT SENSORS

MEDTRONIC MINIMED, INC., ...

1. A continuous glucose monitoring system comprising:
an orthogonally redundant glucose sensor device for determining the concentration of glucose in a body of a user, said sensor
device comprising an optical glucose sensor and an electrochemical glucose sensor; and

a transmitter operatively coupled to said electrochemical and optical glucose sensors and having a housing, wherein the transmitter
includes sensor electronics in said housing, said sensor electronics including at least one physical microprocessor that is
configured to:

(a) receive a first signal from the electrochemical glucose sensor and a second signal from the optical glucose sensor, wherein
said second signal is obtained at a first point in time;

(b) receive a meter glucose value, said meter glucose value being indicative of the user's blood glucose (BG) level and being
obtained at a second point in time;

(c) pair said meter glucose value with said second signal;
(d) perform a validity check on the paired meter glucose value and second signal;
(e) calculate a mapped value for the second signal based on the first signal; and
(f) calibrate the mapped value of the second signal based on said first meter glucose value.

US Pat. No. 9,433,731

DETECTING UNINTENTIONAL MOTOR MOTION AND INFUSION DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. A system comprising:
a motor;
a sensing arrangement coupled to the motor to provide output indicative of a detected characteristic of the motor when the
sensing arrangement is enabled; and

a module coupled to the sensing arrangement to:
periodically enable the sensing arrangement to consume current while the motor is idle and disable the sensing arrangement
after each enabling; and

detect potential unintended motion of the motor based on the output from the sensing arrangement while periodically enabling
the sensing arrangement.

US Pat. No. 9,364,177

SENSOR WITH LAYERED ELECTRODES

MEDTRONIC MINIMED, INC., ...

28. An analyte monitoring system comprising:
(a) a planar flexible analyte sensor comprising:
a base layer;
a first electrode layer disposed on the base layer and including a first electrode;
a first insulative layer disposed on the first electrode layer, wherein said first insulative layer leaves at least a portion
of the first electrode exposed;

a second electrode layer disposed on the first insulative layer and including a second electrode;
a second insulative layer disposed on the second electrode layer, wherein said second insulative layer leaves at least a portion
of the second electrode exposed; and

a third electrode layer disposed on the second insulative layer and including a third electrode,
wherein the first electrode layer further includes a first conductive trace leading from the first electrode to a first conductive
pad configured to electrically couple to sensor electronics, the second electrode layer further includes a second conductive
trace leading from the second electrode to a second conductive pad configured to electrically couple to sensor electronics,
the third electrode layer further includes a third conductive trace leading from the third electrode to a third conductive
pad configured to electrically couple to sensor electronics, the first, second, and third electrodes are in a staggered configuration,
and the maximum height of the flexible analyte sensor is about 25 microns; and

wherein each of said base layer, said first, second, and third electrode layers, and said first and second insulative layers
is planar, and said exposed portion of the first electrode and said exposed portion of the second electrode are configured
to be in direct contact with a patient's bodily fluids for measuring said analyte within the patient's body;

(b) sensor electronics electrically connected to the first, second, and third conductive pads; and
(c) an analyte monitor, wherein the sensor electronics and the analyte monitor are configured to communicate with one another.

US Pat. No. 9,265,890

SYRINGE PISTON WITH FINNED SEALING COVER

Medtronic MiniMed, Inc., ...

1. A syringe piston comprising:
a piston body having a tip, a base opposite the tip, and an outer seal-retaining surface between the tip and the base, the
base including a retaining shoulder that extends outwardly from the base and the base defines a cavity;

a piston sealing cover coupled to the piston body, the piston sealing cover overlying the tip and coupled around the outer
seal-retaining surface, and the piston sealing cover comprising a fin-shaped fluid seal element to form an interference fluid
seal with an interior wall of a syringe barrel, the fin-shaped fluid seal element located near the tip of the piston body
and having a surface that faces the base of the piston body, the piston sealing cover including a circumferential end seal
element that extends outwardly from the piston sealing cover, the circumferential end seal element spaced a distance apart
from the fin-shaped fluid seal element along the piston sealing cover, and the piston sealing cover is coupled to the piston
body such that the circumferential end seal element contacts the retaining shoulder of the base,

wherein the surface is concave.

US Pat. No. 9,237,865

ANALYTE SENSORS AND METHODS FOR MAKING AND USING THEM

Medtronic MiniMed, Inc., ...

1. An analyte sensor apparatus for implantation within a mammal, the analyte sensor apparatus comprising:
a base layer;
a conductive layer disposed upon the base layer wherein the conductive layer includes a working electrode;
an analyte sensing layer disposed on the conductive layer, wherein the analyte sensing layer detectably alters the electrical
current at the working electrode in the conductive layer in the presence of an analyte; and

an analyte modulating layer disposed on the analyte sensing layer,
wherein:
the analyte modulating layer modulates the diffusion of the analyte therethrough;
the analyte modulating layer comprising a hydrophilic comb-copolymer having a central chain and a plurality of side chains
coupled to the central chain;

the hydrophilic comb-copolymer comprises a polydimethyl siloxane monomethacrylate, methyl methacrylate; and methoxy poly(ethylene
oxide)monomethacrylate comb-copolymer;

the analyte modulating layer exhibits a glucose diffusion coefficient of between 2.3×10?9 cm2/s and 140×10?9 cm2/s; and

the analyte modulating layer comprises:
30-50 wt % polydimethyl siloxane monomethacrylate;
30-55 wt % methyl methacrylate; and
15-25 wt % methoxy poly(ethylene oxide)monomethacrylate,
such that the comb-copolymer exhibits a molecular weight from 139 kg/mol to 196 kg/mol.

US Pat. No. 9,220,840

MODULAR EXTERNAL INFUSION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An external infusion device for infusing a fluid into a user's body comprising:
a portable first module configured to be worn by the user, the first module including:
a first housing;
an alarm in the first housing;
a reservoir in the first housing to hold a fluid; and
a pump in the first housing to pump the fluid from the reservoir; and
a portable second module configured to removably attach to the first module so as to form a unitary portable device, the second
module including:

a second housing; and
a display in the second housing,
wherein the second module further includes a sensor interface, the sensor being a continuous glucose sensor, wherein the second
module communicates with the first module to provide a fluid delivery program for the flow of the fluid from the first housing,
wherein the unitary portable device is configured to be worn under the user's clothing, and wherein the alarm is triggered
when the user's glucose level value goes beyond an allowed value range.

US Pat. No. 9,180,248

INFUSION DEVICE WITH BASE PORTION AND DURABLE PORTION

MEDTRONIC MINIMED, INC., ...

1. A delivery device for delivering infusion media to a patient, comprising:
a base portion comprising a plate-like member having a bottom surface that secures to the patient's skin;
a cannula extending from the plate-like member of the base portion and into the patient's skin once the delivery device is
secured to the patient; and

a durable portion that mates with and attaches directly to the plate-like member of the base portion to form a housing of
the delivery device and is separable from the plate-like member of the base portion, the durable portion including a drive
device having a drive motor and drive linkage components, the drive device housed entirely within the durable portion and
coupled to a reservoir contained in the delivery device to drive the infusion media from the reservoir through the cannula
and into the patient in a controlled manner;

wherein the drive linkage components include a component that is arranged to be in direct contact with a piston plunger of
the reservoir when the durable portion is mated with the plate-like member of the base portion, and to be separated from the
piston plunger of the reservoir when the durable portion is separated from the plate-like member of the base portion.

US Pat. No. 9,101,710

SEALING ASSEMBLY WITH PINCH VALVE STRUCTURE FOR A FLUID INFUSION DEVICE HAVING A NEEDLED FLUID RESERVOIR

Medtronic MiniMed, Inc., ...

1. A sealing assembly for a fluid infusion device that cooperates with a fluid reservoir having a reservoir port and a hollow
fluid reservoir needle at least partially located within the reservoir port, the sealing assembly comprising:
a reservoir port receptacle to receive the reservoir port such that the reservoir port receptacle resides inside the reservoir
port, and the reservoir port receptacle comprising a proximal end, a distal end extending from the proximal end, and a needle
entry formed in the distal end to receive the hollow fluid reservoir needle;

a flow base component coupled to the reservoir port receptacle, the flow base component having an inlet structure extending
therefrom, the inlet structure terminating at an abutment surface;

a fluid chamber located at least partially in the reservoir port receptacle, the fluid chamber at least partially defined
in the flow base component; and

a sealing component positioned inside the reservoir port receptacle to cooperate with the fluid chamber, the sealing component
comprising:

a needle sealing element comprising a base section adjacent to the fluid chamber, the base section in contact with the abutment
surface of the inlet structure of the flow base component to form a seal against the inlet structure, a sleeve extending from
the base section and coupled around an exterior of the inlet structure, an end section opposite the base section, a neck section
between the base section and the end section, and a needle opening extending through the base section, the neck section, and
the end section, wherein the needle opening accommodates the hollow fluid reservoir needle of the fluid reservoir when the
reservoir port of the fluid reservoir engages the reservoir port receptacle, and wherein the hollow fluid reservoir needle
fluidly communicates with the fluid chamber when the reservoir port of the fluid reservoir engages the reservoir port receptacle;
and

a compression element coupled around the neck section to impart an inward biasing force near the needle opening.

US Pat. No. 9,861,748

USER-CONFIGURABLE CLOSED-LOOP NOTIFICATIONS AND INFUSION SYSTEMS INCORPORATING SAME

MEDTRONIC MINIMED, INC., ...

1. An infusion system comprising:
one or more user interface elements;
a motor operable to deliver fluid to a user, delivery of the fluid influencing a condition of the user;
a sensing arrangement to obtain a sensor value indicative of the condition of the user;
a data storage element to store alert configuration information for the user; and
a control system coupled to the motor, the sensing arrangement, the data storage element, and the one or more user interface
elements to:

operate the motor in a closed-loop mode to deliver the fluid to the user based at least in part on a difference between a
target value for the condition of the user and the sensor value;

identify an alert condition based at least in part on the alert configuration information for the user while operating the
motor in the closed-loop mode; and

in response to identifying the alert condition:
provide a user notification via the one or more user interface elements in accordance with the alert configuration information;
and

operate the motor in an alternative control mode;
receive a user response after providing the user notification; and
thereafter operate the motor to deliver the fluid to the user in a manner that is influenced by the user response.

US Pat. No. 9,693,722

SENSOR WITH LAYERED ELECTRODES

MEDTRONIC MINIMED, INC., ...

1. A planar flexible analyte sensor comprising:
a base layer;
a first electrode layer disposed on the base layer and including a first electrode;
a first insulative layer disposed on the first electrode layer, wherein said first insulative layer leaves at least a portion
of the first electrode exposed;

a second electrode layer disposed on the first insulative layer and including a second electrode; and
a second insulative layer disposed on the second electrode layer, wherein said second insulative layer leaves at least a portion
of the second electrode exposed,

wherein each of said base layer, first and second electrode layers, and first and second insulative layers is planar, wherein
said exposed portion of the first electrode and said exposed portion of the second electrode are configured to be in direct
contact with a patient's bodily fluids for measuring said analyte within the patient's body, and wherein the maximum height
of the flexible analyte sensor is about 25 microns.

US Pat. No. 9,610,431

PRESSURE VENTED FLUID RESERVOIR HAVING A MOVABLE SEPTUM

Medtronic MiniMed, Inc., ...

1. A fluid reservoir for a fluid infusion device that delivers a medication fluid to a body, the fluid reservoir comprising:
a main body section that defines a fluid chamber for the medication fluid;
a fluid delivery port coupled to and extending from the main body section, the fluid delivery port comprising a fluid conduit
that communicates with the fluid chamber, and the fluid delivery port terminating at a port opening; and

a valve sleeve movably coupled to the fluid delivery port and having a septum maintained therein, in a fixed position relative
to the valve sleeve, such that the septum translates, relative to the fluid delivery port and in concert with the valve sleeve,
between a sealed position where the septum forms a circumferential seal around the port opening, and a vented position that
permits fluid to flow out of the fluid delivery port via the port opening, wherein the valve sleeve comprises:

an attachment receptacle that receives the fluid delivery port, the attachment receptacle being sized to accommodate translational
movement of the valve sleeve relative to the fluid delivery port; and

a septum receptacle adjacent to the attachment receptacle, wherein the septum receptacle receives and holds the septum in
the fixed position.

US Pat. No. 9,579,452

MEDICATION RESERVOIR

Medtronic MiniMed, Inc., ...

1. An apparatus for engaging or disengaging a housing of an infusion device, the apparatus comprising:
a cap having a cylindrical external surface;
a fluid conduit coupled to the cap;
a retractable detent arm formed within and defining a portion of the circumference of the cap and adapted to engage a lock
recess disposed in a circular rim of the housing of the infusion device;

a first tab disposed on the cap so as to provide a first surface for a user to grip, wherein:
the first tab projects outward from the cap; and
gripping and twisting the first tab rotates the cap and engages or disengages the housing.

US Pat. No. 10,073,948

MEDICAL DATA MANAGEMENT SYSTEM AND PROCESS

MEDTRONIC MINIMED, INC., ...

1. A system for managing medical data on a communication network, the system comprising at least one server connectable for communication on the communication network with at least one healthcare provider computer, at least one computer of an authorized payor entity, and computers of other users, the at least one server being configured for:receiving payment request information from the at least one healthcare provider computer, the payment request information being associated with a medical treatment of a first subject by a healthcare provider;
storing the received payment request information having individual identifiers that identify the first subject in a first storage area of one or more databases, storing medical data having individual identifiers for each of the first subject and a second subject in the first storage area, and storing medical data that is free of individual identifiers for each of the first subject and the second subject in a second storage area of the one or more databases, the medical data being associated with the medical treatment of each of the first subject and the second subject by the at least one healthcare provider;
providing access to stored payment request information in the first storage area for the authorized payor entity, but not for other users on the communication network;
providing access to the stored medical data in the first storage area corresponding to the first subject for the authorized payor entity, but not the stored medical data in the first storage area corresponding to the second subject; and
providing access to the stored medical data corresponding to each of the first and second subjects without the individual identifiers in the second storage area for the authorized payor entity and the other users on the communication network.

US Pat. No. 9,744,290

SMART CONNECTION INTERFACE

Medtronic MiniMed, Inc., ...

1. A connector interface system, comprising:
a cap to connect to a reservoir to form a reservoir/cap unit for installation into an infusion pump device; and
at least one magnetic detectable feature arranged on the cap for detection by at least one sensor element on the infusion
pump device when the reservoir of the reservoir/cap unit is received in a reservoir receptacle of the infusion pump device,

wherein the at least one magnetic detectable feature comprises a magnetic field angle of a magnet that is attached to a housing
of the cap, the magnetic field angle being an angle of orientation of a magnetic field of the magnet relative to a predefined
axis of the cap or the reservoir/cap unit, the magnetic field angle being non-parallel and non-perpendicular to the predefined
axis; and

wherein the at least one magnetic detectable feature is arranged at a location on the cap to be detected by the at least one
sensor element when the reservoir or the cap of the reservoir/cap unit is in a fully installed and stationary position relative
to the infusion pump device.

US Pat. No. 9,707,336

PRIMING DETECTION SYSTEM AND METHOD OF USING THE SAME

MEDTRONIC MINIMED, INC., ...

1. An infusion system having at least one reactive element to indicate a component of the infusion system is primed with a
fluid to be delivered into an individual's body, the infusion system comprising:
a delivery device for attaching directly to and delivering the fluid into the individual's body, wherein the delivery device
is an infusion pump or an infusion set;

a delivery element having a proximal end and a distal end, the distal end configured to penetrate the individual's body and
the proximal end connected to and not removable from the delivery device, to provide fluid communication between the delivery
device and the individual's body, wherein the delivery element is a cannula or a needle;

wherein the at least one reactive element is provided directly on at least a portion of a surface of the delivery element;
wherein the fluid is a therapeutic agent and the therapeutic agent is insulin; and
the at least one reactive element reacts with the insulin when the insulin contacts the at least one reactive element to produce
a color change on at least the portion of the surface of the delivery element, wherein the color change indicates that the
delivery element of the infusion system is primed with the insulin.

US Pat. No. 9,642,568

ORTHOGONALLY REDUNDANT SENSOR SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A continuous glucose monitoring system comprising:
an orthogonally redundant glucose sensor, comprising:
an optical glucose sensor including a lightguide on a first respective substrate and having a proximal portion that is disposed
externally to a body of a user and a distal portion configured for internal placement in the user's body, wherein the optical
glucose sensor includes an assay having a glucose receptor, a glucose analog, and a first fluorophore; and

a non-optical glucose sensor including at least one electrode on a second respective substrate and having a proximal portion
that is disposed externally to the user's body and a distal portion configured for internal placement in the user's body,

wherein said first and second respective substrates are integrated into an integrated flex circuit, wherein said lightguide
is disposed in an interior of said integrated flex circuit and said at least one electrode is disposed on an external surface
of said integrated flex circuit;

an insertion device including an insertion needle, wherein said integrated flex circuit is configured to be carried inside
said needle for simultaneous insertion of said optical glucose sensor and said non-optical glucose sensor into the user's
body;

a hand-held monitor having a display; and
an external transmitter having a housing that houses the proximal portion of the optical glucose sensor and the proximal portion
of the non-optical glucose sensor, wherein the transmitter includes instrumentation in said housing configured to receive
an optical signal from the optical sensor and a non-optical signal from the non-optical sensor and configured to convert each
of said optical and non-optical signals to respective glucose values, and wherein the transmitter is configured to wirelessly
transmit said respective glucose values.

US Pat. No. 9,616,165

GLUCOSE SENSOR PRODUCT

Medtronic MiniMed, Inc., ...

1. A glucose sensor product comprising:
a plastic package tray;
a glucose sensor assembly in the plastic package tray, the glucose sensor assembly comprising an electrochemical sensor with
glucose oxidase enzyme, a sensor base formed at least in part from plastic, a sensor mounting pedestal formed at least in
part from plastic, and a sensor introducer formed at least in part from plastic; and

a microbial barrier material coupled to the plastic package tray to seal the glucose sensor assembly in the plastic package
tray, wherein the microbial barrier material maintains sterility of the glucose sensor assembly while venting substances outgassed
from the plastic package tray, the sensor base, the sensor mounting pedestal, and the sensor introducer.

US Pat. No. 9,610,401

INFUSION SET COMPONENT WITH MODULAR FLUID CHANNEL ELEMENT

MEDTRONIC MINIMED, INC., ...

1. An infusion set component for a fluid infusion device that delivers fluid to a patient, the infusion set component comprising:
a base; and
a fluid channel module coupled to the base;
the base comprising:
a base body section having a first rail spaced apart from a second rail, the base body section configured to accommodate removable
coupling with a fluid tubing connector of the fluid infusion device;

a cavity defined between the first rail and the second rail of the base body section, the cavity having a first end substantially
opposite a second end, and the second end of the cavity is open to receive the fluid channel module between the first rail
and the second rail;

a lock tab positioned at the first end of the cavity; and
the fluid channel module comprising:
a body section that defines an interior fluid flow channel to receive fluid from the fluid tubing connector, the body section
including a resilient hook that deflects around the lock tab during insertion of the fluid channel module within the cavity
and the body section is received within the cavity such that the body section is positioned between the first rail and the
second rail; and

a conduit in fluid communication with the interior fluid flow channel to deliver fluid from the interior fluid flow channel,
wherein the interior fluid flow channel and the conduit cooperate to form a fluid flow path and the conduit comprises a hollow
needle having a first end located within the interior fluid flow channel, and a second end to deliver fluid to the patient.

US Pat. No. 9,610,402

TRANSCUTANEOUS CONDUIT INSERTION MECHANISM WITH A LIVING HINGE FOR USE WITH A FLUID INFUSION PATCH PUMP DEVICE

Medtronic MiniMed, Inc., ...

1. An insertion mechanism for actuating a transcutaneous conduit assembly having a fluid conduit and a needle, wherein at
least a portion of the needle is initially inside the fluid conduit, the insertion mechanism comprising:
a first sliding block coupled to the fluid conduit to move the fluid conduit in an insertion direction;
a second sliding block coupled to the needle to move the needle in the insertion direction and in a retraction direction,
wherein movement of the second sliding block in the insertion direction pushes the first sliding block in the insertion direction;

a torsion spring; and
a living hinge coupled between the torsion spring and the second sliding block, wherein rotation of the torsion spring during
an insertion action actuates the living hinge to move the second sliding block in the insertion direction and, thereafter,
in the retraction direction, and wherein:

the living hinge comprises N living hinge segments integrally formed with N?1 flexible junction segments;
each of the flexible junction segments serves as a hinge for two adjacent living hinge segments; and
N is an integer greater than one.

US Pat. No. 9,555,190

FLUID RESERVOIR SEATING PROCEDURE FOR A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A method of seating a fluid reservoir in a housing of a fluid infusion device prior to establishing an outgoing fluid flow
path from the fluid reservoir, the fluid infusion device comprising a drive motor assembly, an actuation mechanism operatively
coupled to the drive motor assembly for actuation of a plunger of the fluid reservoir, and a force sensor operatively coupled
to the actuation mechanism, the method comprising:
detecting insertion of the fluid reservoir into the housing, wherein insertion of the fluid reservoir into the housing causes
a shaft of the plunger to engage the actuation mechanism;

after detecting insertion of the fluid reservoir, obtaining a first measure of force using the force sensor, wherein the first
measure of force is associated with interaction of the shaft with the actuation mechanism;

comparing the first measure of force to a first threshold force value;
when the first measure of force is greater than the first threshold force value, depressurizing the fluid reservoir;
after depressurizing the fluid reservoir, or when the first measure of force is not greater than the first threshold force
value, rewinding the drive motor assembly to achieve an equilibrium state for the fluid reservoir; and

after rewinding the drive motor assembly to achieve the equilibrium state, advancing the drive motor assembly to obtain an
initial seated state for the fluid reservoir.

US Pat. No. 9,517,303

RESERVOIR PLUNGER POSITION MONITORING AND MEDICAL DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. An infusion device, comprising:
a housing including a voided region to receive a reservoir, the voided region including a voided portion to receive a shaft
portion including a shaft coupled to a plunger of the reservoir, the shaft portion comprising a detectable feature; and

a sensing arrangement proximate the voided portion to sense the detectable feature when the reservoir is inserted in the voided
region, wherein resistance of the sensing arrangement is influenced by contact with the detectable feature, wherein:

the sensing arrangement comprises:
a bottom conductive layer comprising a substantially rigid material having a first conductive resistive carbon ink layer;
an upper conductive layer comprising a flexible material having a second conductive resistive carbon ink layer aligned with
the first conductive resistive carbon ink layer on the bottom conductive layer; and

a spacer layer between the bottom conductive layer and the upper conductive layer, the bottom conductive layer and the upper
conductive layer being spaced apart from one another by the spacer layer in the absence of a compressive force applied to
the upper conductive layer; and

the resistance corresponds to a location where the upper conductive layer is compressed by the detectable feature.

US Pat. No. 10,141,882

MOTOR HEALTH MONITORING AND MEDICAL DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. A method of detecting degradation in a drive system including a motor, the method comprising:applying a modulated voltage to the motor;
adjusting a duty cycle of the modulated voltage to achieve a commanded rotation of a rotor of the motor; and
identifying a degradation condition based on the duty cycle.

US Pat. No. 9,943,256

METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT SENSORS

MEDTRONIC MINIMED, INC., ...

1. A continuous glucose monitoring system comprising:an orthogonally redundant glucose sensor device for determining the concentration of glucose in a body of a user, said sensor device comprising an optical glucose sensor and an electrochemical glucose sensor; and
an external transmitter operatively coupled to said electrochemical and optical glucose sensors and having a housing, wherein the transmitter includes sensor electronics in said housing, said sensor electronics including at least one physical microprocessor that is configured to:
receive a first signal from the electrochemical glucose sensor and a second signal from the optical glucose sensor;
perform a respective integrity check on each of said first and second signals;
determine whether the first signal can be calibrated, and whether the second signal can be calibrated, wherein said determination is made based on whether the first signal and the second signal pass or fail their respective integrity checks;
if it is determined that the first signal can be calibrated, calibrate said first signal to generate an electrochemical sensor glucose (SG) value;
if it is determined that the second signal can be calibrated, calibrate said second signal to generate an optical sensor glucose (SG) value; and
fuse said electrochemical SG value and said optical SG value to calculate a single, fused sensor glucose value for the orthogonally redundant glucose sensor device,
wherein said optical glucose sensor includes a lightguide on a first respective substrate, said electrochemical glucose sensor includes at least one electrode on a second respective substrate, and said first and second respective substrates are integrated into an integrated flex circuit; and
wherein said lightguide is disposed in an interior of said integrated flex circuit and said at least one electrode is disposed on an external surface of said integrated flex circuit.

US Pat. No. 9,880,528

MEDICAL DEVICES AND RELATED UPDATING METHODS AND SYSTEMS

MEDTRONIC MINIMED, INC., ...

1. A medical device comprising:
a motor operable to deliver a fluid influencing a condition of a user;
one or more data storage elements to maintain control information utilized by a control scheme or algorithm implemented by
the medical device to determine commands for operating the medical device and network identification information for authenticating
an intermediate device paired with the medical device; and

a control module coupled to the motor and the one or more data storage elements to autonomously operate the motor to deliver
the fluid based at least in part on the control information and one or more measured values for the condition of the user
to autonomously regulate the condition, automatically establish a temporary communication session with the intermediate device
over a network in response to a request from the intermediate device, obtain updated control information from the intermediate
device via the temporary communication session, overwrite the control information in the one or more data storage elements
with the updated control information to store the updated control information in the one or more data storage elements, and
after the control information is updated, autonomously operate the motor based at least in part on the updated control information
and one or more subsequent measured values for the condition of the user to autonomously regulate the condition.

US Pat. No. 9,863,911

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of performing real-time sensor diagnostics on a subcutaneous or implanted sensor of a sensor system, said sensor
including at least one working electrode and said sensor system including a microprocessor that is operatively connected to
said sensor, the method comprising:
(a) periodically performing an electrochemical impedance spectroscopy (EIS) procedure to generate multiple sets of impedance-related
data for said at least one working electrode;

(b) calculating, by said microprocessor, respective values of a plurality of impedance-related parameters based on said multiple
sets of impedance-related data, said plurality of parameters including impedance, phase angle, and Nyquist slope; and

(c) based on said respective values, determining, by said microprocessor, whether the sensor is functioning normally, wherein
the microprocessor:

(i) performs a first test based on values of real impedance or phase angle;
(ii) performs a second test based on values of respective frequencies at which successive EIS procedures are performed;
(iii) performs a third test based on a comparison of current and post-sensor initialization impedance values at 1 kHz;
(iv) performs a fourth test based on the value of post-sensor initialization impedance at 0.1 Hz;
(v) performs a fifth test based on a global change in the value of Nyquist slope between 0.1 Hz and 1 Hz;
(vi) performs a sixth test based on a change, over time, in the magnitude of real impedance;
(vii) determines that the sensor is functioning normally if at least 3 of said first through sixth tests are satisfied by
generating results that fall within respective predetermined criteria,

wherein the microprocessor determines that the first test is satisfied if either |(Zn?ZI)/ZI|>30% at 1 kHz, wherein Z1 is
the value of real impedance measured at a first EIS run and Zn is the value of real impedance measured at a subsequent EIS
run, or the phase angle change is greater than 10° at 0.1 Hz between said first and subsequent EIS runs,

wherein the microprocessor determines that the second test is satisfied if, at a phase angle of ?45°, the difference in frequency
between two consecutive EIS runs (f2-fl) is greater than 10 Hz, and

wherein the microprocessor determines that the third test is satisfied if the current value of impedance is less than the
post-initialization value of impedance at 1 kHz.

US Pat. No. 9,854,998

METHOD AND/OR SYSTEM FOR MULTICOMPARTMENT ANALYTE MONITORING

Medtronic Minimed, Inc., ...

1. A method comprising:
estimating, using a controller of a glucose control system, a latency in transportation of an analyte between first and second
physiological compartments, based, at least in part, upon at least one blood glucose reference sample;

compensating for the latency in estimating a concentration of the analyte in the first physiological compartment based, at
least in part, on one or more observations of a concentration of the analyte in the second physiological compartment by:

accumulating over time a plurality of difference values between a sensor signal value and an offset value to provide an accumulation
result;

combining a term with the accumulation result to provide a combined expression, wherein the term includes the estimated latency;
and

determining the estimated concentration based, at least in part, on a computed rate of change in the combined expression;
and

wherein the method further comprises generating, using the controller, a command to one or more infusion pumps based, at least
in part, on the estimated concentration.

US Pat. No. 9,839,378

OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION

MEDTRONIC MINIMED, INC., ...

1. An optical device for determining blood glucose concentration, comprising:
at least one excitation light source that emits at least one excitation light signal;
a fiber optic sensor optically coupled to the at least one excitation light source and comprising an indicator system comprising
a fluorophore operably coupled to a glucose binding moiety, wherein upon absorption of at least a portion of the at least
one excitation light signal, the indicator system emits at least a first emission light signal and a second emission light
signal, wherein the first and second emission light signals are each related to glucose concentration, and wherein a ratio
of the first and second emission light signals is glucose insensitive and the ratio is related to pH levels; and

a detector system operably coupled to at least the sensor, wherein the detector system is adapted to detect the first and
second emission light signals.

US Pat. No. 9,839,753

SYSTEMS FOR MANAGING RESERVOIR CHAMBER PRESSURE

Medtronic MiniMed, Inc., ...

1. A fluid infusion device, comprising:
a housing having a reservoir chamber that receives a fluid reservoir and a pump chamber;
a drive system contained within the pump chamber of the housing and a slide of the drive system is movable relative to the
fluid reservoir for dispensing fluid from the fluid reservoir;

a seal disposed between the reservoir chamber and the pump chamber that defines an opening and the slide is movable relative
to the seal through the opening; and

a pressure management system at least partially defined in the slide of the drive system, the pressure management system including
at least one air conduit that cooperates with the opening of the seal to vent air from the reservoir chamber into the pump
chamber.

US Pat. No. 9,795,738

INTELLIGENT THERAPY RECOMMENDATION ALGORITHIM AND METHOD OF USING THE SAME

Medtronic MiniMed, Inc., ...

1. A method of automatically making a therapy recommendation for adjusting a basal rate stored on an insulin pump, the method
comprising the steps of:
obtaining a blood glucose value at the end of a time interval;
determining if an intervening event occurred during the time interval , wherein the intervening event changes the blood glucose
value unrelated to the stored basal rate and thereby interferes with recommending a change to the stored basal rate;

recommending no change to the stored basal rate based on the blood glucose value if the intervening event occurred during
the time interval;

updating a recommended change to the stored basal rate based on a previous day recommended change to the stored basal rate
during that interval and the difference between the blood glucose value and a target blood glucose level if no intervening
event occurred during the time interval;

comparing an absolute value of the updated recommended change to a predefined threshold value of the stored basal rate;
making no therapy recommendation if the updated recommended change does not exceed the threshold or the therapy recommendation
is not within safety parameters;

making the therapy recommendation if the updated recommended change exceeds the threshold and the therapy recommendation is
within safety parameters; and

displaying the therapy recommendation to adjust the stored basal rate.

US Pat. No. 9,681,828

PHYSIOLOGICAL CHARACTERISTIC SENSORS AND METHODS FOR FORMING SUCH SENSORS

MEDTRONIC MINIMED, INC., ...

1. A method for forming a physiological characteristic sensor, the method comprising the steps of:
immersing a sensor electrode in a platinum electrolytic bath; and
performing an electrodeposition process by sequentially applying a pulsed signal to the sensor electrode, wherein the pulsed
signal includes a repeated cycle of a first current and a second current different from the first current, and applying a
non-pulsed continuous signal to the sensor electrode, wherein the non-pulsed continuous signal includes a non-repeated application
of a third current, for from about 50 seconds to about 240 seconds to form a platinum deposit on the sensor electrode.

US Pat. No. 9,625,414

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of calibrating a sensor, comprising:
performing an electrochemical impedance spectroscopy (EIS) procedure for a working electrode of a sensor to obtain values
of at least one impedance-based parameter for said working electrode;

performing a bound check on said values of the at least one impedance-based parameter to determine whether said at least one
impedance-based parameter is in-bounds and, based on said bound check, calculating a reliability-index value for said working
electrode; and

determining, based on the value of said reliability index, whether calibration should be performed, or whether calibration
should be delayed until a later time.

US Pat. No. 9,610,405

CONNECTION AND ALIGNMENT DETECTION SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A medical device for treating a user, the device comprising:
a first housing portion adapted to be carried by a user;
a second housing portion configured to be selectively operatively engaged with and disengaged from the first housing portion,
the first housing portion and the second housing portion configured to be movable relative to each other from a first position
to a second position in a predefined direction to operatively engage each other at the second position;

a first interactive element supported on the first housing portion;
a second interactive element supported on the second housing portion in a position to interact with the first interactive
element when the first housing portion and the second housing portion are in the first position;

a third interactive element supported on the second housing portion in a position to interact with the first interactive element
when the first housing portion and the second housing portion are in the second position, wherein the second interactive element
and the third interactive element are arranged relative to each other along the predefined direction and spaced apart from
each other in the predefined direction;

at least one guiding structure arranged on the second portion configured to guide movement of the first portion or the second
portion from the first position to the second position; and

electronic circuitry configured to detect at least one of a first interaction between the first interactive element and the
second interactive element, and a second interaction between the first interactive element and the third interactive element,
the circuitry configured to provide a signal or a change in state in response to detection of at least one of the first interaction
and the second interaction.

US Pat. No. 9,603,561

METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT SENSORS

MEDTRONIC MINIMED, INC., ...

1. A method of calculating a single, fused sensor glucose (SG) value based on respective output signals of an electrochemical
glucose sensor and an optical glucose sensor of an orthogonally redundant glucose sensor device, the method comprising:
performing a status check on each of the electrochemical glucose sensor and the optical glucose sensor, wherein said status
check on the electrochemical glucose sensor is based on at least one of a previous cal ratio, a previous sensor accuracy,
a sensitivity loss flag, and a dip flag for the electrochemical glucose sensor;

calculating a first reliability index for the output signal of the electrochemical sensor based on said status check for the
electrochemical sensor;

calculating a second reliability index for the output signal of the optical sensor based on said status check for the optical
sensor;

calibrating the output signal of the electrochemical sensor to obtain an electrochemical sensor glucose value (echem SG);
calibrating the output signal of the optical sensor to obtain an optical sensor glucose value (optical SG);
calculating a first weight based on said first reliability index and calculating a weighted echem SG based on said first weight;
calculating a second weight based on said second reliability index and calculating a weighted optical SG based on said second
weight; and

calculating said single, fused sensor glucose value based on said weighted echem SG and said weighted optical SG.

US Pat. No. 9,517,299

SMART CONNECTION INTERFACE

MEDTRONIC MINIMED, INC., ...

1. An infusion pump system, comprising:
an infusion pump device having a reservoir receptacle to receive a reservoir containing infusion media and to selectively
dispense the infusion media from the reservoir when the reservoir is received within the reservoir receptacle;

the reservoir for containing the infusion media;
at least one sensor element held by the infusion pump device;
a connector interface to connect the reservoir with the infusion pump device, the connector interface comprising a cap to
connect to the reservoir to form a reservoir/cap unit; and

at least one magnetic detectable feature arranged on the cap for detection by the at least one sensor element on the infusion
pump device when the reservoir of the reservoir/cap unit is received in the reservoir receptacle of the infusion pump device,

wherein the at least one magnetic detectable feature comprises a magnetic field angle of a magnet that is attached to a housing
of the cap, the magnetic field angle being an angle of orientation of a magnetic field of the magnet relative to a predefined
axis of the cap or the reservoir/cap unit, the magnetic field angle being non-parallel and non-perpendicular to the predefined
axis;

wherein the magnetic field angle of the at least one magnetic detectable feature is at least one detectable parameter that
is associated with one or more characteristics of the cap, the reservoir, a cannula, or a tubing connected between the cap
and the cannula; and

wherein one or more predefined characteristics of the cap, the reservoir, the cannula, or the tubing connected between the
cap and the cannula comprises a type or identity of a manufacturer of the cap, the reservoir, the cannula or the tubing, or
a size of the cap, the reservoir, the cannula or the tubing.

US Pat. No. 9,364,612

NEEDLE INSERTION SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A medical device, the device comprising:
a medical monitoring or treatment device configured to provide a monitoring or treatment operation on a user;
a base adapted to be secured to the user, in contact with clothing or skin of the user during operation of the medical monitoring
or treatment device, the base having an internal area;

a cannula housing structure adapted to be secured to the user, the cannula housing further adapted to be in contact with clothing
or skin of the user during operation of the medical monitoring or treatment device, the cannula housing structure is located
within the internal area of the base, the cannula housing structure connected to an supported by the base, the cannula housing
structure having a body, the cannula housing structure and the base configured for relative movement therebetween, the cannula
housing structure arranged to be separate and apart from the base;

a cannula extending through the body of the cannula housing structure during operation of the medical monitoring or treatment
device, the cannula for inserting into the skin of the user for operation of the medical monitoring or treatment device;

a flexible connection connecting the base and the cannula housing structure for allowing relative movement between the cannula
housing structure and the base while the cannula housing structure is located within the internal area of the base, after
the cannula is inserted into the skin of the user and during operation of the medical monitoring or treatment device;

a first adhesive material provided on at least a portion of the cannula housing structure, the first adhesive material having
an adhesion strength for adhering the cannula housing to the clothing or skin of the user; and

a second adhesive material provided on at least a portion of the base, the second adhesive material having an adhesion strength
for adhering the base to the clothing or skin of the user;

wherein the cannula housing structure is supported within the internal area of the base and the internal area of the base
includes a space around the cannula housing structure for allowing relative movement in an axial direction and a lateral direction
between the cannula housing structure and the base, while the cannula is in the skin of the user, and while the base is adhered
to the clothing or skin of the user, and

wherein the flexible connection connecting the base and the cannula housing structure is configured to allow relative movement
between the cannula housing structure and the base while the cannula is locked in an extended state when the cannula is in
the skin of the user for operation of the medical monitoring or treatment device.

US Pat. No. 10,152,049

GLUCOSE SENSOR HEALTH MONITORING AND RELATED METHODS AND SYSTEMS

MEDTRONIC MINIMED, INC., ...

1. A method of providing indication when replacement of an interstitial glucose sensing element of a sensing arrangement should be performed in connection with operating an infusion device operable to deliver fluid to a user based on measurements indicative of an interstitial fluid glucose level of the user provided by the sensing arrangement, the fluid influencing the physiological condition of the user, the method comprising:obtaining, by a control module coupled to the interstitial glucose sensing element of the sensing arrangement, a plurality of uncalibrated measurements corresponding to a monitoring period based on output signals provided by the sensing element, wherein the output signals are influenced by the interstitial fluid glucose level of the user;
obtaining, by the control module, a calibration factor for converting the plurality of uncalibrated measurements to a plurality of calibrated measurement values for the physiological condition;
for each respective measurement of the plurality of uncalibrated measurements:
determining a second derivative metric associated with the respective measurement based at least in part on a difference between a first derivative metric associated with the respective measurement and the first derivative metric associated with the preceding measurement of the plurality of uncalibrated measurements, wherein the second derivative metric associated with a most recent measurement of the plurality of uncalibrated measurements comprises the greater of a difference between the first derivative metric associated with the most recent measurement and the first derivative metric associated with the immediately preceding measurement of the plurality of uncalibrated measurements and an average magnitude of second derivative metric values associated with the plurality of uncalibrated measurements; and
scaling the second derivative metric associated with the respective measurement by the calibration factor to determine a noise metric for the respective measurement of the plurality of uncalibrated measurements;
determining, by the control module, a number of high noise measurements for the monitoring period based on the noise metrics for the respective measurements of the plurality of uncalibrated measurements;
determining, by the control module, an output measurement value indicative of the interstitial fluid glucose level based at least in part on the most recent measurement of the plurality of uncalibrated measurements and at least one of the first derivative metric associated with the most recent measurement and the second derivative metric associated with the most recent measurement;
transmitting, by a communications interface coupled to the control module, the output measurement value to the infusion device, wherein a delivery command for operating a motor of the infusion device to autonomously control delivery of the fluid to the user is determined based at least in part on the output measurement value and the calibration factor; and
providing, via an output interface of the sensing arrangement, indication replacement of the interstitial glucose sensing element should be performed when a reliability metric influenced by the number of high noise measurements violates a first threshold.

US Pat. No. 9,872,954

BELT CLIP

Medtronic MiniMed, Inc., ...

1. A belt clip assembly, comprising:
a device retainer having a first retainer, the device retainer further defined to retain a clip pin;
a clip being coupled to the device retainer via the clip pin, the clip further having a detent and being defined to retain
a tab pin; and

a tab coupled to the clip via the tab pin, the tab being rotatable about the tab pin,
wherein the device retainer is initially rotatable about the clip pin independent of rotation of the tab about the tab pin,
such that rotation of the device retainer about the clip pin results in a finite displacement of the device retainer.

US Pat. No. 9,861,746

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method for real-time detection of low start-up for a working electrode of a glucose sensor, the method comprising:
inserting the sensor into subcutaneous tissue;
periodically performing an electrochemical impedance spectroscopy (EIS) procedure to generate multiple sets of impedance-related
data for said working electrode;

calculating, by a microprocessor, for each of said multiple sets of impedance-related data, respective values of 1 kHz real
impedance and Nyquist slope;

monitoring and analyzing, by said microprocessor, said respective values of 1 kHz real impedance and Nyquist slope over time
by comparing the 1 kHz real impedance and Nyquist slope to respective specified ranges for said real impedance and Nyquist
slope; and

based on said monitoring and analyzing, determining, by said microprocessor, whether said working electrode is experiencing
low start-up,

wherein use of said sensor for glucose measurement is delayed or sensor glucose values are blinded to a user of the sensor
by the microprocessor based on the determination that the working electrode is experiencing low start-up.

US Pat. No. 9,849,239

GENERATION AND APPLICATION OF AN INSULIN LIMIT FOR A CLOSED-LOOP OPERATING MODE OF AN INSULIN INFUSION SYSTEM

MEDTRONIC MINIMED, INC., ...

1. An insulin infusion device comprising:
an insulin reservoir for insulin to be delivered from the insulin infusion device to a user;
a processor architecture comprising at least one processor device; and
at least one memory element associated with the processor architecture, the at least one memory element storing processor-executable
instructions that, when executed by the processor architecture, perform a method of controlling closed-loop delivery of insulin
from the insulin reservoir to the user, the method comprising:

calculating a maximum insulin infusion rate for the user based on a fasting blood glucose value associated with the user,
a total daily insulin value associated with the user, and fasting insulin delivery data that is indicative of insulin delivered
to the user during a fasting period, wherein the maximum insulin infusion rate is applicable during a period of closed-loop
operation of the insulin infusion device;

obtaining a first closed-loop insulin infusion rate for the user, wherein the first closed-loop insulin infusion rate is obtained
for a current sampling point during the period of closed-loop operation;

providing a second closed-loop insulin infusion rate for the user when the obtained first closed-loop insulin infusion rate
is greater than the calculated maximum insulin infusion rate, wherein the second closed-loop insulin infusion rate is less
than the first closed-loop insulin infusion rate; and

operating the insulin infusion device in a closed-loop mode to continuously deliver insulin from the insulin reservoir to
the user in accordance with either the first closed-loop insulin infusion rate or the second closed-loop insulin infusion
rate.

US Pat. No. 9,849,240

DATA MODIFICATION FOR PREDICTIVE OPERATIONS AND DEVICES INCORPORATING SAME

MEDTRONIC MINIMED, INC., ...

1. A system comprising:
a sensing arrangement to obtain a sequence of measurements of a condition in a body of a user, the sensing arrangement including
a sensing element providing a signal indicative of the condition; and

a control module coupled to the sensing arrangement, the sensing arrangement and the control module being cooperatively configured
to identify one or more unusable measurements in the sequence of measurements, modify a value for the one or more unusable
measurements in the sequence of measurements, resulting in a modified sequence of measurements, determine an estimate of a
trend in the sequence of measurements based at least in part on differences between consecutive measurements of the modified
sequence of measurements, and determine a predicted value for the condition in the body of the user at a time in the future
based at least in part on a current value for the condition and the estimate of the trend, wherein:

the one or more unusable measurements are replaced in the modified sequence with an interpolated value based on a preceding
usable measurement in the sequence and a succeeding usable measurement in the sequence when a number of measurement samples
corresponding to a gap between the preceding usable measurement and the succeeding usable measurement is less than an interpolation
threshold;

the one or more unusable measurements are backfilled with the succeeding usable measurement when the number of measurement
samples corresponding to the gap is greater than the interpolation threshold; and

the control module is configured to operate a medical device in a manner that is influenced by the predicted value.

US Pat. No. 9,833,563

SYSTEMS FOR MANAGING RESERVOIR CHAMBER PRESSURE

Medtronic MiniMed, Inc., ...

1. A fluid infusion device, comprising:
a housing defining a reservoir chamber that receives a fluid reservoir and a second chamber, the reservoir chamber includes
a wall adjacent to the fluid reservoir;

a drive system contained within the housing for dispensing fluid from the fluid reservoir; and
a plurality of bores defined through the wall of the reservoir chamber, each of the plurality of bores having a first end
in communication with the reservoir chamber and a second end in communication with the second chamber to define an airflow
path to manage air pressure in the reservoir chamber, each of the plurality of bores having a centerline that is substantially
parallel to a longitudinal axis of the reservoir chamber.

US Pat. No. 9,744,301

EXTERNAL INFUSION DEVICE WITH REMOTE PROGRAMMING, BOLUS ESTIMATOR AND/OR VIBRATION ALARM CAPABILITIES

Medtronic MiniMed, Inc., ...

1. An external infusion device for infusing insulin into a body of a user from a reservoir, the external infusion device comprising:
a device housing for use on an exterior of the body and sized to be held in a hand of the user;
a drive mechanism at least partially contained within the housing and coupled to the reservoir for infusing insulin into the
body of the user from the reservoir;

a processor contained within the housing and coupled to the drive mechanism;
a memory contained within the housing and coupled to the processor for storing a target glucose level and an insulin sensitivity;
a display device contained within the housing and coupled to the processor for displaying information to the user, wherein
the display device includes a touch screen input device for enabling the user to input a current glucose level of the user;
and

a bolus estimator contained within the housing and used in conjunction with the processor and the display device including
the touch screen input device to calculate a bolus of insulin to be infused based upon the current glucose level, the target
glucose level, and the insulin sensitivity, wherein the calculated bolus of insulin to be infused is displayed to the user
on the display device, and the touch screen input device further enables the user to accept or adjust the calculated bolus
of insulin.

US Pat. No. 9,744,291

SMART CONNECTION INTERFACE

Medtronic MiniMed, Inc., ...

1. An infusion pump system, comprising:
an infusion pump device having a reservoir receptacle to receive a reservoir containing infusion media and to selectively
dispense the infusion media from the reservoir when the reservoir is received within the reservoir receptacle;

the reservoir for containing the infusion media;
at least one sensor element held by the infusion pump device;
a connector interface to connect the reservoir with the infusion pump device, the connector interface comprising a cap to
connect to the reservoir to form a reservoir/cap unit; and

at least one magnetic detectable feature arranged on the cap for detection by at least one sensor element on the infusion
pump device when the reservoir of the reservoir/cap unit is received in the reservoir receptacle of the infusion pump device,

wherein the at least one magnetic detectable feature comprises a magnetic field angle of a magnet that is attached to a housing
of the cap, the magnetic field angle being an angle of orientation of a magnetic field of the magnet relative to a predefined
axis of the cap or the reservoir/cap unit, the magnetic field angle being non-parallel and non-perpendicular to the predefined
axis; and

wherein the at least one magnetic detectable feature is arranged at a location on the cap to be detected by the at least one
sensor element when the reservoir or the cap of the reservoir/cap unit is in a fully installed and stationary position relative
to the infusion pump device.

US Pat. No. 9,625,415

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

MEDTRONIC MINIMED, INC., ...

1. A method of calculating a single, fused sensor glucose value based on respective glucose measurement signals of a plurality
of redundant sensing electrodes, comprising:
performing respective electrochemical impedance spectroscopy (EIS) procedures for each of the plurality of redundant sensing
electrodes to obtain values of at least one impedance-based parameter for each said sensing electrode;

measuring the electrode current (Isig) for each of the plurality of redundant sensing electrodes;
calibrating each of the measured Isigs to obtain respective calibrated sensor glucose values;
calculating a bound-check reliability index and a noise-check reliability index for each said sensing electrode based on said
measured Isig and said values of the at least one impedance-based parameter;

calculating a dip reliability index for each said sensing electrode based on one or more of said at least one impedance-based
parameter;

calculating a sensitivity-loss reliability index for each said sensing electrode based on one or more of said at least one
impedance-based parameter; and

calculating said single, fused sensor glucose value based on the respective bound-check reliability index, noise-check reliability
index, dip reliability index, sensitivity-loss reliability index and calibrated sensor glucose values of each of the plurality
of redundant sensing electrodes.

US Pat. No. 9,592,335

INSULIN PUMP DATA ACQUISITION DEVICE

MEDTRONIC MINIMED, INC., ...

1. An insulin pump data acquisition device comprising:
an insulin pump casing having an interior volume;
an environmental sensor operable to generate environmental data in response to environmental conditions;
memory operably connected to the environmental sensor, the memory being operable to store the environmental data;
a controller operably connected to the environmental sensor and the memory, the controller being operable to control reading
of the environmental data from the environmental sensor and writing of the environmental data to the memory; and

a battery operably connected to power the environmental sensor, the memory, and the controller;
wherein the environmental sensor, the memory, the controller, and the battery are disposed within the interior volume, wherein
the insulin pump casing is the same size as a battery selected from the group consisting of a AA battery and a AAA battery.

US Pat. No. 9,579,066

DETERMINATION AND APPLICATION OF GLUCOSE SENSOR RELIABILITY INDICATOR AND/OR METRIC

Medtronic Minimed, Inc., ...

1. A method comprising:
determining an indicator of reliability of a blood glucose sensor, the blood glucose sensor comprising at least a first probe
and a second probe, the first and second probes comprising two or more pairs of sensor elements, the indicator of reliability
of the blood glucose sensor being based, at least in part, on an observed correlation of output signals generated by at least
a first pair of the pairs of sensor elements; and

generating a signal to suggest replacement of the blood glucose sensor based, at least in part, on the indicator of reliability
of the blood glucose sensor.

US Pat. No. 9,579,454

COORDINATION OF CONTROL COMMANDS IN A MEDICAL DEVICE SYSTEM BASED ON SYNCHRONIZATION STATUS BETWEEN DEVICES

Medtronic MiniMed, Inc., ...

1. A method of coordinating control commands in a medical device system comprising a medical device that delivers therapy
to a patient, and a wireless controller device for the medical device, the method comprising:
obtaining a user input at the wireless controller device, the user input corresponding to a request to initiate a command
that influences therapy delivered by the medical device;

in response to the user input, checking a synchronization status between the wireless controller device and the medical device;
transmitting, to the medical device, a control message for the command only when the checking step confirms that status data
of the wireless controller device is synchronized with current status data maintained by the medical device; and

preventing execution of the command when the checking step determines that the status data of the wireless controller device
is not synchronized with the current status data maintained by the medical device.

US Pat. No. 9,549,698

METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS

MEDTRONIC MINIMED, INC., ...

1. A method of stabilizing a glucose sensor having a plurality of electrodes for measuring a patient's glucose level, the
method comprising: applying a first stabilization voltage to one of the plurality of electrodes to initiate an anodic cycle
in the sensor, said first stabilization voltage being between 0.8 volts and 1.34 volts; applying a second stabilization voltage
to said one of the plurality of electrodes to initiate a cathodic cycle in the sensor, said second stabilization voltage being
between 0.235 volts and 0.835 volts; repeating, for one or more iterations, the application of the first stabilization voltage
followed by the application of the second stabilization voltage until a measured electrical characteristic of the sensor meets
a predetermined criterion which indicates sensor stabilization; measuring the patient's glucose level with the electrodes,
and beginning to use said measured glucose levels of the patient's glucose level after the sensor is stabilized.

US Pat. No. 9,533,096

MICROPROCESSOR CONTROLLED AMBULATORY MEDICAL APPARATUS WITH HAND HELD COMMUNICATION DEVICE

MEDTRONIC MINIMED, INC., ...

1. A communication system for a medical device, the system comprising:
an ambulatory medical device (MD) configured to provide a treatment to a body of a patient having a housing, the MD further
including within the housing: (1) a reservoir capable of containing a drug, (2) a pumping mechanism for transferring the drug
from the reservoir to the body of a patient, (3) a MD electronic control circuitry that further comprises at least one MD
telemetry system and at least one MD processor that controls, at least in part, operation of the MD telemetry system and operation
of the MD, including, at least in part, operation of the pumping mechanism, and wherein a first portion of the MD telemetry
system is incorporated into the MD processor and a second portion of the MD telemetry system is external to the MD processor,
and (4) a MD memory; and

a communication device (CD) comprising:
at least one CD telemetry system configured to send messages to or receive messages from the MD telemetry system;
at least one CD memory; and
at least one CD processor that controls, at least in part, operation of the CD telemetry system and operation of the CD, wherein
the MD is configured to selectively disable a MD component or activity of a MD component for transmission or reception of
messages by the MD telemetry system, further wherein the MD is configured to selectively enable and disable the MD telemetry
system; and

wherein the MD is configured to disable the MD component or activity of the MD component when the MD telemetry system is enabled.

US Pat. No. 9,533,132

PRESSURE VENTED FLUID RESERVOIR FOR A FLUID INFUSION DEVICE

Medtronic MiniMed, Inc., ...

1. A fluid infusion device that delivers a medication fluid to a body, the fluid infusion device comprising:
a base plate;
a hollow fluid delivery needle coupled to the base plate to provide a fluid flow path for the medication fluid;
a sealing element coupled to the base plate and overlying at least a portion of the hollow fluid delivery needle, the sealing
element comprising:

a base section;
a tip section extending from the base section; and
a retractable body section between the base section and the tip section; and
a fluid reservoir comprising:
a main body section that defines a fluid chamber for the medication fluid;
a plunger to expel the medication fluid from the fluid chamber when actuated;
a fluid delivery port coupled to and extending from the main body section, the fluid delivery port comprising a fluid conduit
and a pressure vent defined therein; and

a septum located in the fluid delivery port and having a nominal non-pierced state forming a seal within the fluid conduit;
wherein the pressure vent provides a venting conduit from inside the fluid chamber to outside the fluid chamber;
wherein the pressure vent terminates at an exterior and exposed surface of the fluid delivery port, the exterior and exposed
surface contoured to mate with a resilient sealing element of the fluid infusion device to seal the pressure vent; and

wherein the fluid delivery port engages and cooperates with the sealing element and the hollow fluid delivery needle such
that the tip section of the sealing element is urged against the fluid delivery port to seal the pressure vent.

US Pat. No. 9,522,225

ADHESIVE PATCH SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A medical device comprising:
a medical monitoring device comprising a sensor configured to detect a biological parameter on a patient or a treatment device
comprising an electronic infusion pump configured to deliver an infusion medium to a patient, the medical monitoring or treatment
device including and operable with an insertion needle positioned to be inserted into the patient to insert a cannula into
the patient, the insertion needle configured to extend through the cannula when the insertion needle is inserted into a patient
to insert the cannula into the patient, the insertion needle configured to be withdrawn from the cannula to leave the cannula
at least partially in the patient after the cannula is inserted into the patient, the cannula having an interior channel for
conveying fluid to or from the medical monitoring or treatment device after the insertion needle is withdrawn from the cannula
and during operation of the medical monitoring or treatment device;

a pierceable membrane defining an interior volume containing an agent, the pierceable membrane positioned to be pierced by
the insertion needle to allow the insertion needle to cause at least some of the agent contained in the interior volume of
the pierceable membrane to be communicated from the interior volume of the pierceable membrane, outside the cannula, to the
patient as the insertion needle is moved to an insertion position to be inserted into the patient with the cannula; and

a base adapted to be secured to the patient during operation of the medical monitoring or treatment device, the base having
a bottom surface that is arranged to contact a portion of the skin of the patient when the base is secured to the patient;

wherein the pierceable membrane is arranged on and attached to the bottom surface of the base such that the insertion needle
is external to the internal volume of the pierceable membrane when the needle begins to move toward the insertion position,
and such that the insertion needle passes through the pierceable membrane on the bottom surface of the base as the insertion
needle continues to move to the insertion position; and

wherein the pierceable membrane is positioned between a portion of the bottom surface of the base and the skin of the patient
in a case where the base is secured to the patient during operation of the medical monitoring or treatment device.

US Pat. No. 9,402,569

SYSTEM AND/OR METHOD FOR GLUCOSE SENSOR CALIBRATION

Medtronic Minimed, Inc., ...

4. An apparatus comprising:
a sensor to generate signal values (ISIG) responsive to a blood glucose concentration in a body; and
a special purpose computing apparatus programmed to:
obtain a sequence of blood glucose reference measurements taken from said body; and
derive a non-linear mapping between said signal values and blood glucose concentration in said body to calibrate a glucose
monitor for observing blood glucose characteristics in said body based, at least in part, on temporal pairings of at least
some of said blood glucose reference measurements with said signal values, wherein said non-linear mapping is derived by deriving
a piece-wise function that maps sensor signal values to blood glucose concentration, the piece-wise function comprising at
least one linear portion and at least one non-linear portion, the at least one non-linear portion being derived at least in
part by a determination of coefficients e, f, and g corresponding to the following function:

blood-glucose reference measurement=(ISIG+e)f+g; and

use, at least in part, said determined coefficients e, f and g in calibrating subsequent signal values received by said glucose
monitor to provide one or more estimated blood glucose levels corresponding to said subsequent signal values.

US Pat. No. 9,295,786

NEEDLE PROTECTIVE DEVICE FOR SUBCUTANEOUS SENSORS

MEDTRONIC MINIMED, INC., ...

1. An introducer configured to insert a sensor into a patient, the introducer comprising:
a housing detachably connectable to a sensor hub containing a sensor, wherein the sensor hub contains the sensor prior to
connection to the housing, the housing having a top side and a base and including a needle cover, wherein the needle cover
is an internal compartment of the housing;

a needle that is moveable with respect to the needle cover and is extendable out of, and retractable into, the housing;
a needle holder connected to the needle and contained within the housing, wherein the needle holder has a top portion having
an upper surface and an undersurface; and

a spring having a top end and a bottom end, wherein the undersurface of the needle holder's top portion rests on the spring's
top end at all times, and wherein the spring's bottom end rests on the housing's base at all times,

wherein the introducer is configured such that, when the housing is connected to the sensor hub, the needle holder is in a
needle extended position and the needle extends out of the housing to insert the sensor into the patient, and disconnection
of the housing from the sensor hub causes the needle holder to move in the housing to a needle covered position such that
the needle is covered by the needle cover inside the housing and the sensor remains inserted in the patient;

wherein said needle holder and spring are configured such that, when the housing is connected to the sensor hub, said spring
is in a compressed position, and such that disconnection of the housing from the sensor hub causes said spring to expand,
thereby moving the needle holder towards the needle covered position and retracting the needle into the housing to be covered
by said needle cover;

wherein the housing includes a mating component to mate with the sensor hub and hold said spring in a compressed position
when the housing is connected to the sensor hub;

wherein the mating component includes a lock that locks the needle holder into the needle extended position when the housing
is connected to the sensor hub; and

wherein said upper surface of the needle holder's top portion abuts said top side of the housing when the needle holder is
in the needle covered position.

US Pat. No. 10,086,134

SYSTEMS FOR SET CONNECTOR ASSEMBLY WITH LOCK

Medtronic MiniMed, Inc., ...

1. A fluid infusion device, comprising:a removable fluid reservoir;
a housing that defines an opening that receives the removable fluid reservoir and the housing includes a retaining ring having a lock, the retaining ring surrounds the opening; and
a set connector assembly removably coupled to the housing to define a fluid flow path from the fluid infusion device, the set connector assembly including a connector having a body that defines a graspable portion and a coupling portion, the coupling portion receivable within the opening of the housing and coupled to the removable fluid reservoir, the graspable portion having a main branch and at least one wing coupled to the main branch that defines a locking tab for engaging the lock, the main branch extending from the coupling portion, the main branch defines a bore that extends along a longitudinal axis of the connector to define the fluid flow path, the locking tab extends outward from the at least one wing beyond a perimeter of the coupling portion of the connector to engage the lock and the at least one wing is movable relative to the coupling portion to disengage the locking tab with the lock.

US Pat. No. 10,001,450

NONLINEAR MAPPING TECHNIQUE FOR A PHYSIOLOGICAL CHARACTERISTIC SENSOR

MEDTRONIC MINIMED, INC., ...

1. A method of measuring blood glucose of a patient, the method comprising:applying a constant voltage potential to a glucose sensor;
obtaining a constant potential sensor current from the glucose sensor, wherein the constant potential sensor current is generated in response to applying the constant voltage potential to the glucose sensor;
performing an electrochemical impedance spectroscopy (EIS) procedure for the glucose sensor to obtain EIS output measurements; and
performing a nonlinear mapping operation on the constant potential sensor current and the EIS output measurements to generate a blood glucose value.

US Pat. No. 9,839,741

FLANGED SEALING ELEMENT AND NEEDLE GUIDE PIN ASSEMBLY FOR A FLUID INFUSION DEVICE HAVING A NEEDLED FLUID RESERVOIR

Medtronic MiniMed, Inc., ...

1. A sealing assembly for a fluid infusion device that cooperates with a fluid reservoir having a reservoir port and a hollow
fluid reservoir needle at least partially located within the reservoir port, the sealing assembly comprising:
a reservoir port receptacle to receive the reservoir port, and comprising a proximal end, a distal end extending from the
proximal end, and a needle entry formed in the distal end to receive the hollow fluid reservoir needle;

a fluid chamber located at least partially in the reservoir port receptacle; and
a sealing component positioned in the reservoir port receptacle to cooperate with the fluid chamber, the sealing component
comprising:

a needle guide pin protruding from the proximal end of the reservoir port receptacle, wherein an end section of the needle
guide pin is sized to fit within the hollow fluid reservoir needle; and

a needle sealing element that cooperates with the hollow fluid reservoir needle and with the needle guide pin, the needle
sealing element comprising a base section adjacent to the fluid chamber, an end section opposite the base section, a neck
section between the base section and the end section, and a needle opening extending through the neck section.

US Pat. No. 9,719,505

MEDICATION PUMP TEST DEVICE AND METHOD OF USE

MEDTRONIC MINIMED, INC., ...

1. A test system comprising:
a depth indicator comprising a fixed portion; and
a test device installed on the depth indicator, the test device comprising:
an internal body portion; and
an external body portion that defines a depth indicator recess that receives the fixed portion of the depth indicator, wherein
a junction of the internal body portion and the external body portion define an external contact portion that contacts a medication
pump,

wherein the test device maintains the fixed portion of the depth indicator at a fixed axial position along a central axis
relative to the medication pump when the fixed portion of the depth indicator is seated in the depth indicator recess, the
external contact portion contacts the medication pump, and the internal body portion is seated in an open end of a reservoir
compartment of the medication pump.

US Pat. No. 9,687,194

CLOSED-LOOP GLUCOSE AND/OR INSULIN CONTROL SYSTEM

Medtronic Minimed, Inc., ...

1. A method comprising:
determining a recommended therapy for a patient derived from signals representative of blood-glucose sensor measurements;
and

generating a signal to initiate an alarm to an attendant in response to detection of a suggested change in said recommended
therapy based, at least in part, on signals representative of subsequent blood-glucose sensor measurements and an indication
of a predetermined predisposition for hypoglycemia in said patient obtained independently of said subsequent blood-glucose
sensor measurements.

US Pat. No. 9,649,059

METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT SENSORS

MEDTRONIC MINIMED, INC., ...

1. A continuous glucose monitoring system comprising:
an orthogonally redundant glucose sensor device comprising an optical glucose sensor and an electrochemical glucose sensor;
and

a transmitter operatively coupled to said electrochemical and optical glucose sensors and having a housing, wherein the transmitter
includes sensor electronics in said housing, said sensor electronics including at least one physical microprocessor that is
configured to:

perform a status check on each of the electrochemical glucose sensor and the optical glucose sensor, wherein said status check
on the electrochemical glucose sensor is based on at least one of a previous cal ratio a previous sensor accuracy, a sensitivity
loss flag, and a dip flag for the electrochemical glucose sensor;

calculate a first reliability index for an output signal of the electrochemical sensor based on said status check for the
electrochemical sensor;

calculate a second reliability index for an output signal of the optical sensor based on said status check for the optical
sensor;

calibrate the output signal of the electrochemical sensor to obtain an electrochemical sensor glucose value (echem SG);
calibrate the output signal of the optical sensor to obtain an optical sensor glucose value (optical SG);
calculate a first weight based on said first reliability index and generate a weighted echem SG based on said first weight;
calculate a second weight based on said second reliability index and generate a weighted optical SG based on said second weight;
and

calculate a single, fused sensor glucose value for the orthogonally redundant glucose sensor device based on said weighted
echem SG and weighted optical SG.

US Pat. No. 9,539,386

ON-BODY INJECTOR AND METHOD OF USE

MEDTRONIC MINIMED, INC., ...

1. An electronic injector for use with a patient to deliver a fluid, the electronic injector comprising:
a fluid reservoir operable to hold the fluid;
a MEMS pump in fluid communication with the fluid reservoir;
a needle fitting adapted to receive an injection needle, the needle fitting being in fluid communication with the MEMS pump;
a battery having a DC power output;
a regulator operably connected to the battery to convert the DC power output to a pump drive signal in response to a regulator
control signal;

a microcontroller operably connected to the regulator to provide the regulator control signal; and
a housing to enclose the battery, the regulator, the microcontroller, the fluid reservoir, and the MEMS pump;
wherein the MEMS pump is responsive to the pump drive signal to control flow of the fluid from the fluid reservoir, through
the MEMS pump, through the injection needle, and into the patient;

wherein the MEMS pump is a piezoelectric MEMS pump comprising:
a case defining a working chamber, the working chamber having a piezoelectric wall responsive to a first pump drive signal
voltage and a second pump drive signal voltage;

a one way inlet valve operable to permit flow of the fluid from the fluid reservoir to the working chamber and to block reverse
flow of the fluid from the working chamber to the fluid reservoir; and

a one way outlet valve operable to permit flow of the fluid from the working chamber to the needle fitting and to block reverse
flow of the fluid from the needle fitting to the working chamber;

wherein the piezoelectric wall increases volume of the working chamber in response to the first pump drive signal voltage
to draw the fluid from the fluid reservoir through the one way inlet valve to the working chamber;

wherein the piezoelectric wall decreases the volume of the working chamber in response to the second pump drive signal voltage
to force the fluid from the working chamber through the one way outlet valve to the needle fitting;

the electronic injector further comprising:
an injection port in fluid communication with a delivery tube, the injection port lying on an injection axis;
the injection needle in fluid communication with the MEMS pump, the injection needle having an injection needle tip aligned
with the injection port, the injection needle being slideably biased away from the injection port to define a gap between
the injection needle tip and the injection port; and

a needle button operably connected to the injection needle to slide the injection needle along the injection axis;
wherein the needle button is operable to advance the injection needle tip to close the gap and advance the injection needle
tip into the injection port to form a bolus injection flow path from the fluid reservoir, through the MEMS pump, through the
injection needle, through the delivery tube, and into the patient; and

wherein the needle button is further operable to activate the MEMS pump to deliver a predetermined bolus volume to the patient
through the bolus injection flow path in response to a bolus pump drive signal.

US Pat. No. 9,541,519

AMPEROMETRIC SENSOR ELECTRODES

Medtronic MiniMed, Inc., ...

1. An amperometric sensor electrode comprising a plurality of electrodeposited metal layers comprising:
(a) a base substrate comprising a polyimide;
(b) a first metal layer comprising gold or chrome disposed on the base substrate and having a first surface area and a first
adhesion strength with the base substrate on which the first metal layer is disposed; and

(c) a second metal layer comprising platinum electrodeposited on the first metal layer, the second metal layer having a second
surface area and a second adhesion strength with the first layer on which the second layer is electrodeposited, wherein the
second surface area is greater than the first surface area and the second adhesion strength is greater than the first adhesion
strength.

US Pat. No. 9,463,309

SEALING ASSEMBLY AND STRUCTURE FOR A FLUID INFUSION DEVICE HAVING A NEEDLED FLUID RESERVOIR

Medtronic MiniMed, Inc., ...

1. A sealing assembly for a fluid infusion device that cooperates with a fluid reservoir having a reservoir port and a hollow
fluid reservoir needle at least partially located within the reservoir port, the sealing assembly comprising:
a reservoir port receptacle to receive the reservoir port, and comprising a proximal end, a distal end extending from the
proximal end, and a needle opening formed in the distal end to receive the hollow fluid reservoir needle, the reservoir port
receptacle residing within the reservoir port when engaged therewith, and the hollow fluid reservoir needle residing within
the reservoir port receptacle when the reservoir port engages the reservoir port receptacle;

a first fluid chamber located within the reservoir port receptacle;
a second fluid chamber separated from the reservoir port receptacle;
a cap component coupled to the reservoir port receptacle, the cap component having an outlet conduit formed therein, the outlet
conduit having a first end in fluid communication with the first fluid chamber and having a second end in fluid communication
with the second fluid chamber and with a delivery conduit of the fluid infusion device, and the cap component having a protruding
section that terminates at an abutment surface, the protruding section extending into the reservoir port receptacle and having
an interior area that defines the first fluid chamber; and

a needle sealing element having a self-sealing needle opening formed therein, the needle sealing element located within the
reservoir port receptacle between the distal end of the reservoir port receptacle and the abutment surface of the cap component,
wherein the self-sealing needle opening accommodates the hollow fluid reservoir needle when the reservoir port engages the
reservoir port receptacle, wherein:

the hollow fluid reservoir needle terminates at a blunt tip;
the needle sealing element comprises a tapered opening to receive the blunt tip; and
engagement of the reservoir port with the reservoir port receptacle causes the blunt tip to penetrate the self-sealing needle
opening to establish fluid communication from the hollow fluid reservoir needle to the first fluid chamber.

US Pat. No. 9,931,460

SMART CONNECTION INTERFACE

Medtronic MiniMed, Inc., ...

1. An infusion pump system, comprising:an infusion pump device having a reservoir receptacle to receive a reservoir containing infusion media and to selectively dispense the infusion media from the reservoir when the reservoir is received within the reservoir receptacle;
the reservoir for containing the infusion media;
at least one sensor element held by the infusion pump device;
a connector interface to connect the reservoir with the infusion pump device, the connector interface comprising a cap to connect to the reservoir to form a reservoir/cap unit; and
at least one magnetic detectable feature arranged on the cap for detection by at least one sensor element on the infusion pump device when the reservoir of the reservoir/cap unit is received in the reservoir receptacle of the infusion pump device,
wherein the at least one magnetic detectable feature comprises a magnetic field angle of a magnet that is attached to a housing of the cap, the magnetic field angle being an angle of orientation of a magnetic field of the magnet relative to a predefined axis of the cap or the reservoir/cap unit;
wherein the magnetic field angle of the at least one magnetic detectable feature is at least one detectable parameter that is associated with one or more characteristics of the cap, the reservoir, a cannula, or a tubing connected between the cap and the cannula;
wherein the one or more characteristics of the cap, the reservoir, the cannula, or the tubing connected between the cap and the cannula includes a type or identity of a manufacturer of the cap, the reservoir, the cannula or the tubing, or a size of the cap, the reservoir, the cannula or the tubing; and
wherein the magnetic field angle is detected by the at least one sensor element when the cap is in a proper or fully installed position within the reservoir receptacle of the infusion pump device.

US Pat. No. 9,757,511

PERSONAL MEDICAL DEVICE AND METHOD OF USE WITH RESTRICTED MODE CHALLENGE

MEDTRONIC MINIMED, INC., ...

1. A personal medical device for employment by a user and having a restricted mode, the personal medical device comprising:
a memory operable to store programming code;
a processor operably connected to the memory;
a user input operably connected to the processor and having input buttons to receive input from the user; and
a user display operably connected to the processor to display output to the user;
wherein the processor is responsive to the programming code to:
detect a user request for entry to the restricted mode;
display a user input image on the user display in response to the detected user request, the user input image including display
buttons corresponding to the input buttons;

highlight one of the display buttons;
detect actuation of one of the input buttons on the user input; and
deny entry to the restricted mode when the one of the input buttons does not correspond to the highlighted one of the display
buttons;

wherein the processor being operable to highlight one of the display buttons further comprises the processor being operable
to randomly highlight the one of the display buttons.

US Pat. No. 9,717,845

GEOFENCING FOR MEDICAL DEVICES

MEDTRONIC MINIMED, INC., ...

1. A medical therapy system for both approved and trial therapies, the medical therapy system comprising:
an infusion pump having a case, the case containing a processor, memory, a drive mechanism, a reservoir, communication hardware
and a sensor suite; and

the sensor suite including a global positioning system (GPS) receiver to determine GPS coordinates of the infusion pump, the
GPS receiver being coupled to the processor that executes first instructions stored in the memory, the first instructions
corresponding to an approved therapy, the processor executing second instructions stored in the memory when the location of
the infusion pump is within a safe zone defined around specified GPS coordinates, wherein the safe zone is a measured distance
around the specified GPS coordinates, the second instructions corresponding to a trial therapy, wherein in response to detecting
the location of the infusion pump as being removed from the safe zone, operation of the infusion pump reverts to executing
the first instructions.

US Pat. No. 9,662,445

REGULATING ENTRY INTO A CLOSED-LOOP OPERATING MODE OF AN INSULIN INFUSION SYSTEM

MEDTRONIC MINIMED, INC., ...

1. An electronic device comprising:
a processor architecture comprising at least one processor device; and
at least one memory element associated with the processor architecture, the at least one memory element storing processor-executable
instructions that, when executed by the processor architecture, cause the processor architecture to:

obtain sensor calibration data for a continuous glucose sensor that generates a sensor variable indicative of blood glucose
of the user;

identify a most recent calibration factor from the sensor calibration data, the most recent calibration factor representing
a first conversion value applicable to convert a first value of the sensor variable to a first blood glucose value;

identify a prior calibration factor from the sensor calibration data, the prior calibration factor representing a second conversion
value applicable to convert a second value of the sensor variable to a second blood glucose value, and the prior calibration
factor corresponding to an earlier time relative to the most recent calibration factor; and

permit entry into a closed-loop operating mode of an insulin infusion device for a user based on the most recent calibration
factor and the prior calibration factor only when t?tRecent?tR?t, wherein:

t is a time when attempting to enter the closed-loop operating mode;
tRecent is a predetermined time period;
tR is a time when the most recent calibration factor was obtained; and
the insulin infusion device operation in the closed-loop operating mode to deliver insulin to a body of the user is influenced
by the most recent calibration factor.

US Pat. No. 9,518,813

SENSING SYSTEMS AND METHODS

MEDTRONIC MINIMED, INC., ...

1. A medical device for treating a user, the medical device comprising:
a first housing portion adapted to be carried by a user;
a second housing portion configured to be selectively operatively engaged with and disengaged from the first housing portion;
a plurality of electrical contacts provided on at least one of the first housing portion and the second housing portion, the
plurality of electrical contacts including a set of main electrical contacts and at least one other electrical contact;

a shorting mechanism provided on the other of the first housing portion and the second housing portion, the shorting mechanism
for contacting the set of main electrical contacts to establish an electrical connection with the main electrical contacts;

a magnetic source having at least one of a certain magnetic field and a certain magnetic strength provided on at least one
of the first housing portion and the second housing portion;

a sensor for detecting at least one of the certain magnetic field and the certain magnetic strength provided on the other
of the first housing portion and the second housing portion; and

electronic circuitry configured to provide a first signal in a case where the first housing portion and the second housing
portion are brought together and the shorting mechanism contacts the set of main electrical contacts of the plurality of electrical
contacts;

the electronic circuitry configured to provide a second signal in a case where the first housing portion and the second housing
portion are brought together and the shorting mechanism contacts the at least one other electrical contact of the plurality
of electrical contacts;

the electronic circuitry configured to provide a first sensing signal in a case where the first housing portion and the second
housing portion are brought together and the sensor detects at least one of the certain magnetic field and the certain magnetic
strength of the magnetic source; and

the electronic circuitry configured to provide a second sensing signal in a case where the first housing portion and the second
housing portion are brought together and the sensor detects at least one of a magnetic field different from the certain magnetic
field and a magnetic strength different from the certain magnetic strength of the magnetic source.

US Pat. No. 10,455,639

PROTOCOL TRANSLATION DEVICE

Medtronic MiniMed, Inc., ...

1. A protocol translation device comprising:a casing sized to fit within a compartment of a first apparatus;
a translator comprising a translator circuit operably connected between a first antenna that communicates with the first apparatus and a second antenna that communicates with a second apparatus, wherein the translator circuit translates between a first communication protocol used by the first apparatus and a second communication protocol used by the second apparatus; and
a battery operably connected to power the first apparatus in addition to the translator, wherein the translator, which comprises the translator circuit operably connected between the first antenna and the second antenna, and the battery, are all disposed within the casing, wherein the second apparatus is outside the casing.

US Pat. No. 10,039,479

METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT SENSORS

MEDTRONIC MINIMED, INC., ...

1. A method of calculating a single, fused sensor glucose (SG) value based on respective output signals of an electrochemical glucose sensor and an optical glucose sensor of an orthogonally redundant glucose sensor device, the method comprising:performing a status check on each of the electrochemical glucose sensor and the optical glucose sensor;
calculating a first reliability index for the output signal of the electrochemical sensor based on a reliability index for each of sensor dip, sensor noise, sensor sensitivity loss, sensor cal ratio, and sensor accuracy for the electrochemical glucose sensor;
calculating a second reliability index for the output signal of the optical sensor based on said status check for the optical sensor;
calibrating the output signal of the electrochemical sensor to obtain an electrochemical sensor glucose value (echem SG);
calibrating the output signal of the optical sensor to obtain an optical sensor glucose value (optical SG);
calculating a first weight based on said first reliability index and calculating a weighted echem SG based on said first weight;
calculating a second weight based on said second reliability index and calculating a weighted optical SG based on said second weight; and
calculating said single, fused sensor glucose value based on said weighted echem SG and said weighted optical SG.

US Pat. No. 9,999,721

ERROR HANDLING IN INFUSION DEVICES WITH DISTRIBUTED MOTOR CONTROL AND RELATED OPERATING METHODS

Medtronic MiniMed, Inc., ...

1. An infusion device comprising:a motor operable to deliver fluid to a body of a user;
a first control module to enable input power for the motor and provide a dosage command for operating the motor; and
a second control module coupled to the first control module to receive the dosage command and operate the motor using at least a portion of the input power based at least in part on the dosage command, wherein one of the first control module and the second control module:
detects an anomalous condition in response to an absence of a communication from the other of the first control module and the second control module; and
in response to the anomalous condition:
disconnects the motor from the input power;
stores diagnostic information for the anomalous condition in an internal memory of the one of the first control module and the second control module; and
after disabling the input power and storing the diagnostic information, reinitializes a processing core of the one of the first control module and the second control module to execute boot loader code.

US Pat. No. 9,999,728

REGULATING ENTRY INTO A CLOSED-LOOP OPERATING MODE OF AN INSULIN INFUSION SYSTEM

Medtronic MiniMed, Inc., ...

1. A method of operating an insulin infusion device to deliver insulin to a body of a user, the method comprising:obtaining sensor calibration data for a glucose sensor that generates a sensor variable indicative of blood glucose of the user;
identifying at least one of a prior calibration factor and a most recent calibration factor from the sensor calibration data, the most recent calibration factor representing a first conversion value applicable to convert a first value of the sensor variable to a first blood glucose value, the prior calibration factor representing a second conversion value applicable to convert a second value of the sensor variable to a second blood glucose value, and the prior calibration factor corresponding to an earlier time relative to the most recent calibration factor;
permitting entry into a closed-loop operating mode of the insulin infusion device only when the at least one of the prior calibration factor and the most recent calibration factor from the sensor calibration data is greater than or equal to a minimum acceptable calibration factor value and less than or equal to a maximum acceptable calibration factor value; and
operating the insulin infusion device in the closed-loop operating mode to deliver insulin to the body of the user in a manner that is influenced by the most recent calibration factor.

US Pat. No. 9,901,305

PHYSIOLOGICAL SENSOR HISTORY BACKFILL SYSTEM AND METHOD

Medtronic MiniMed, Inc., ...

1. A method of sensor history backfill for a local base device operable to wirelessly communicate with a physiological sensor
connected to a patient, the method comprising:
obtaining physiological readings for the patient at a predetermined interval;
storing the physiological readings at the physiological sensor as sensor physiological readings;
storing the physiological readings at the local base device as historic physiological readings;
obtaining a current physiological reading for the patient;
transmitting the current physiological reading to the local base device in a current reading message;
detecting a record gap in the historic physiological readings between the current physiological reading and the historic physiological
readings; and

filling the record gap in the historic physiological readings with sensor physiological readings from the physiological sensor
when the current reading message does not include the sensor physiological readings to fill the record gap,

wherein the filling further comprises:
detecting an End of Day marker that occurred during the record gap, the End of Day marker being stored at the local base device;
and

associating the End of Day marker with the historic physiological readings in the record gap at a time of the End of Day marker.

US Pat. No. 9,889,257

SYSTEMS AND METHODS FOR UPDATING MEDICAL DEVICES

MEDTRONIC MINIMED, INC., ...

1. A system comprising:
a medical device to regulate a condition of a user and maintain first network identification information for an intermediate
device paired with the medical device over a first communications network; and

a remote device to establish an association between the medical device and the intermediate device, maintain second network
identification information for the intermediate device on a second communications network, receive measurement data correlative
to the condition of the user, determine updated control information for the medical device based at least in part on the measurement
data, autonomously initiate establishment of a first peer-to-peer communication session with the intermediate device over
the second communications network by transmitting a connection request to the intermediate device via the second communications
network, and automatically transmit the updated control information to the intermediate device via the first peer-to-peer
communication session in response to receiving an acknowledgment from the intermediate device in response to establishing
a second peer-to-peer communication session with the medical device over the first communications network, wherein:

the medical device receives the updated control information via the second peer-to-peer communication session with the intermediate
device over the first communications network and thereafter autonomously regulates the condition of the user based at least
in part on the updated control information and subsequent measurement data; and

the first communications network and the second communications network are distinct.

US Pat. No. 9,885,650

ACCELERATED LIFE TESTING DEVICE AND METHOD

Medtronic MiniMed, Inc., ...

1. A qualitative testing device comprising:
an enclosure suitable for establishing an atmosphere around a test piece; and
an atmospheric controller operatively connected to the enclosure, the atmospheric controller operable to repeatedly change
between atmospheres in the enclosure to alternately form and remove a deposition layer on the test piece, causing an oxidation
layer to form on the test piece.

US Pat. No. 9,841,014

INSULIN PUMP DATA ACQUISITION DEVICE AND SYSTEM

Medtronic MiniMed, Inc., ...

1. An insulin pump data acquisition device for use with an insulin pump, the data acquisition device comprising:
a holster having a wall defining an interior volume and an exterior volume, the exterior volume being sized to removably secure
the insulin pump;

an environmental sensor operable to generate environmental data in response to environmental conditions;
memory operably connected to the environmental sensor, the memory being operable to store the environmental data;
a controller operably connected to the environmental sensor and the memory, the controller being operable to control reading
of the environmental data from the environmental sensor and writing of the environmental data to the memory;

a battery operably connected to power the environmental sensor, the memory, and the controller; and
a real time clock operably connected to provide timestamps to the controller,
wherein the environmental sensor, the memory, the controller, and the battery are disposed within the interior volume, and
wherein the environmental data includes a plurality of records generated over time, the controller being further operable
to assign one of the timestamps to each of the plurality of records.

US Pat. No. 9,835,580

METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS

MEDTRONIC MINIMED, INC., ...

1. A sensor system, comprising:
a glucose sensor configured to provide a sensor signal indicative of a patient's blood glucose level, the sensor including
a plurality of electrodes that are configured to be implanted or disposed subcutaneously within the patient's body so as to
be in contact with the patient's bodily fluids; and

a sensor electronics device that is coupled to the sensor and includes:
an AC source coupled to a first electrode of the plurality of electrodes and configured to supply an AC signal to said first
electrode for assessing hydration of said plurality of electrodes;

an impedance measuring device configured to measure an impedance within the sensor and to transmit a hydration signal if the
impedance is below a threshold impedance, which indicates hydration of said electrodes;

an electrical detection circuit that receives the hydration signal and generates an interrupt; and
a microcontroller that receives the interrupt from the electrical detection circuit and transmits a signal representative
of a voltage that is to be applied to a second electrode of the plurality of electrodes to generate said sensor signal,

wherein the electrical detection circuit is configured to reduce power consumption of the sensor electronics device by generating
a second interrupt if the sensor has been disconnected from the sensor electronics device, and the microcontroller receives
the second interrupt and generates a signal to turn off power to circuits within the sensor electronics device in response
to the second interrupt, thereby reducing power consumption of the sensor electronics device.

US Pat. No. 9,833,564

FLUID CONDUIT ASSEMBLY WITH AIR VENTING FEATURES

Medtronic MiniMed, Inc., ...

1. A fluid conduit assembly for delivery of a medication fluid, the fluid conduit assembly comprising:
a reservoir cap comprising a lower body section configured to receive and couple to a fluid reservoir, and configured to couple
to a housing of a fluid infusion device to seal and secure the fluid reservoir inside the housing;

a trapping chamber integrally formed in the lower body section of the reservoir cap, the trapping chamber comprising an upper
wall, a delivery hole formed in the upper wall, a plurality of vent holes formed in the upper wall and arranged around the
delivery hole, and an interior volume to receive the medication fluid from the fluid reservoir;

an inlet in fluid communication with the interior volume, the inlet formed in a lower wall of the trapping chamber, the lower
wall opposing the upper wall of the trapping chamber;

a first outlet arrangement for the trapping chamber, the first outlet arrangement accommodating flow of liquid from the interior
volume and inhibiting flow of gas from the interior volume, the first outlet arrangement comprising a first membrane completely
covering the delivery hole, the first membrane having hydrophilic properties;

a length of hollow tubing in fluid communication with the first outlet arrangement by way of the delivery hole formed in the
upper wall; and

a second outlet arrangement for the trapping chamber, the second outlet arrangement accommodating flow of gas from the interior
volume and inhibiting flow of liquid from the interior volume, the second outlet arrangement comprising a second membrane
completely covering the plurality of vent holes, the second membrane having hydrophobic properties;

wherein the first membrane covers the delivery hole without interfering with the second membrane and without interfering with
any of the plurality of vent holes; and

wherein the second membrane comprises a single ring-shaped membrane that surrounds the first membrane without interfering
with the first membrane and without interfering with the delivery hole.

US Pat. No. 9,795,732

DETECTING UNINTENTIONAL MOTOR MOTION AND INFUSION DEVICE INCORPORATING SAME

Medtronic MiniMed, Inc., ...

1. An infusion device comprising:
a motor including a rotor, the rotor having a magnet coupled thereto, wherein rotation of the rotor is configured to provide
translational displacement of a plunger in a fluid reservoir;

a sensing arrangement coupled to the motor, the sensing arrangement comprising one or more sensors to provide output indicative
of a detected magnetic field of the magnet when the sensing arrangement is enabled; and

a module coupled to the sensing arrangement to:
periodically enable the sensing arrangement to consume current while the motor is idle and disable the sensing arrangement
after each enabling; and

detect potential unintended motion of the motor based on the output from the sensing arrangement while periodically enabling
the sensing arrangement.

US Pat. No. 9,682,188

RESERVOIR FLUID VOLUME ESTIMATOR AND MEDICAL DEVICE INCORPORATING SAME

MEDTRONIC MINIMED, INC., ...

1. An infusion device, comprising:
a housing including a voided portion to receive a shaft coupled to a plunger of a reservoir, the shaft further including a
binary code;

a sensing arrangement disposed within the housing proximate to the voided portion, wherein the sensing arrangement includes
an image sensor to detect the binary code and at least one light emitting element oriented towards the shaft to direct light
on the binary code;

a motor having a rotor coupled to the shaft, the shaft being displaced to deliver fluid from the reservoir in response to
rotation of the rotor;

a motor position sensor to measure an amount of rotation of the rotor; and
a control module coupled to the image sensor and the motor position sensor to perform a function based in part on the binary
code detected by the image sensor and based in part on the amount of rotation of the rotor measured by the motor position
sensor, wherein the function performed by the control module includes obtaining a measured position of the shaft using the
binary code detected by the image sensor and determining an expected position of the shaft using the amount of rotation of
the rotor measured by the motor position sensor.

US Pat. No. 9,993,594

OCCLUSION DETECTION TECHNIQUES FOR A FLUID INFUSION DEVICE HAVING A ROTARY PUMP MECHANISM AND ROTOR POSITION SENSORS

Medtronic MiniMed, Inc., ...

1. A fluid pump mechanism comprising:a stator comprising a stator cam element having a stator cam surface;
a rotor comprising a reference surface and a rotor cam element having a variable height rising from the reference surface, the rotor cam element cooperating with the stator cam element to axially displace the rotor, relative to the stator, as a function of angular position of the rotor;
a biasing element that provides a biasing force to urge the rotor cam element toward the stator cam element and toward the reference surface; and
a detection circuit to process axial position data and angular position data of the rotor, and to determine that an upstream occlusion has occurred based on detectable characteristics of the axial and angular position data, wherein the detection circuit calculates axial velocity of the rotor, based on the axial position data, during a fluid expulsion period of the fluid pump mechanism, the fluid expulsion period indicated by the angular position data, and wherein the detection circuit determines that an upstream occlusion has occurred when the calculated axial velocity of the rotor exceeds a threshold axial velocity value.

US Pat. No. 9,937,292

SYSTEMS FOR FILLING A FLUID INFUSION DEVICE RESERVOIR

MEDTRONIC MINIMED, INC., ...

1. A transfer device for filling a fluid reservoir of a fluid infusion device with a fluid, the transfer device comprising:a first end to couple to a source of the fluid;
a second end to couple to a pressurizing device; and
a body interconnecting the first end and the second end and having an end to couple to the fluid reservoir, the body having a first branch coupled to the first end, a second branch coupled to the second end and a third branch that defines the end of the body, the body defining at least one fluid flow path between the source of the fluid, the pressurizing device and the fluid reservoir to enable the filling of the fluid reservoir with the fluid and the body including a one-way duckbill valve that prevents the fluid from entering the source of the fluid located within the first branch and that opens upon the application of a negative pressure to the second end.