US Pat. No. 9,414,931

ARTIFICIAL DISC

Globus Medical, Inc., Au...

1. A surgical method comprising:
performing a total or partial discectomy to remove disc material from the disc space; and
inserting a disc assembly into the disc space via a posterior approach, wherein the disc assembly comprises an upper endplate,
with keels, a lower endplate with keels, a flexible core element and a slider plate,

wherein an extension portion of the upper endplate is adapted it fit within a first cavity in an upper portion of the flexible
core element and an extension portion of the second endplate is adapted to fit within a second cavity in the lower portion
of the flexible core element,

wherein the slider plate is positioned completely within the first cavity in the upper portion of the flexible core element,
and

wherein the extension portion of the first endplate engages with the slider plate to allow translation and rotation.

US Pat. No. 9,295,498

CERVICAL SPINE STABILIZATION SYSTEM WITH EXTENDABLE PLATES

GLOBUS MEDICAL, INC., Au...

1. A surgical method comprising:
providing an extension plate for attachment to a base plate that extends across one or more vertebra, wherein the base plate
comprises a proximal end, a distal end, a plurality of screw holes for receiving screws therein and one or more graft windows,
wherein the extension plate comprises a proximal end, a distal end, a plurality of screw holes for receiving screws therein,
wherein the proximal end of the extension plate comprises a finger portion connectable to the base plate;

positioning the extension plate over the base plate such that the finger portion is received through at least one of the one
or more graft windows of the base plate; and

inserting screws through the plurality of screw holes of the extension plate to secure the extension plate relative to the
base plate.

US Pat. No. 9,364,264

SPINAL IMPLANT CONNECTION ASSEMBLY

GLOBUS MEDICAL, INC., Au...

1. A surgical method comprising:
providing a connection assembly, the connection assembly comprising a housing member for connecting a spinal implant to an
anchor, the housing member comprising a first end portion having a channel in the form of a C-shape for receiving at least
a portion of the spinal implant and a second end portion for receiving the anchor therethrough, wherein the second end portion
includes a first opening and the first end portion includes a second opening, wherein the first opening includes a ribbed
section for accommodating an anchor and a threaded section for accommodating a fastening member, wherein the housing member
includes a longitudinal axis extending along the housing member from the first end portion to the second end portion, wherein
the C-shape channel opens generally coaxially with the longitudinal axis;

inserting the anchor through the first opening of the connection assembly, wherein the anchor comprises a head portion including
a plurality of ridges to engage with the ribbed section of the first opening;

providing a fastening member through the first opening to secure the anchor to the connection assembly, wherein the fastening
member is downwardly positioned onto the anchor;

inserting the spinal implant into the channel of the connection assembly; and
providing a securing member through the second opening to secure the spinal implant to the connection assembly, wherein the
securing member is positioned into the second opening wherein it contacts and pushes the spinal implant toward a wall of the
channel of the housing.

US Pat. No. 9,492,203

FACET JOINT REPLACEMENT INSTRUMENTS AND METHODS

GLOBUS MEDICAL, INC., Au...

1. A method of threading a screw into a bone, the method comprising:
coupling a driver to a first end of the screw, the screw having a proximal threaded attachment portion,
wherein the driver comprises:
an outer sleeve,
an inner shaft in a fixed rotational alignment to the outer sleeve,
a screw coupling, wherein the screw coupling is formed by a blunt end of the inner shaft and an internally threaded distal
end of the outer sleeve having threads complimentary to the threaded attachment portion of the screw, wherein the screw coupling
has a locked configuration in which the blunt end of the inner shaft is in contact with the screw to retain the screw in the
outer sleeve, and an unlocked configuration in which the blunt end of the inner shaft is not in contact with the screw and
the screw is free to separate from the driver,

a handle, and
a lever attached to the handle, wherein when the lever is lifted away from the handle, the inner shaft is pulled away from
the distal end of the outer sleeve, and when the lever is moved toward the handle, the inner shaft is moved toward the internally
threaded distal end of the outer sleeve, thereby moving the screw coupling into the locked configuration;

threading a second end of the screw into the bone until a predetermined length of the first end of the screw protrudes from
the bone;

decoupling the driver from the screw; and
attaching a broach to the proximal threaded attachment portion of the screw after decoupling the driver.

US Pat. No. 9,492,287

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

7. A surgical method comprising:
removing at least a portion of an intervertebral disc from an intervertebral space;
introducing an expandable device into the intervertebral space in an unexpanded position, wherein the device includes a first
endplate, a second endplate, an actuation member and a translation member having at least two upper ramped surfaces and at
least two lower ramped surfaces; and

rotating the actuation member such that the actuation member engages and moves the translation member having the at least
two upper ramped surfaces and at least two lower ramped surfaces such that the at least one of the two upper ramped surfaces
of the translation member pushes against a surface of the second endplate, thereby causing the expandable device to expand
into an expanded position,

wherein the translation member includes a first end and a second end, wherein the act least two upper ramped surfaces of the
translation member are spaced apart in a longitudinal axis between the first end and the second end,

wherein the actuation member comprises a threaded portion and a non-threaded portion, the non-threaded portion of the actuation
member extends through an opening in the first end of the translation member and only extends from the first end to a first
of the at least two upper ramped surfaces of the translation member, wherein a pin member is positioned in the actuation member
to prevent the actuation member from disengaging from the translation member, and the threaded portion of the actuation member
is configured to engage a surface on the first end of the translation member such that when the actuation member is rotated,
the threaded portion pushes against the surface of the first end of the translation member causing expansion of the expandable
device.

US Pat. No. 9,179,903

TISSUE RETRACTOR AND METHOD OF USE

Globus Medical, Inc., Au...

1. A multi-blade retractor system comprising:
a retractor frame comprising a first arm, a second arm, and a third arm, the first and second arms pivotably connected to
the frame and the third arm linearly translatably connected to the frame, the retractor frame operatively coupled to a long
arm;

a first blade coupled to a distal end of the first arm;
a second blade coupled to a distal end of the second arm;
a third blade coupled to a distal end of the third arm; and
a removable attachment mechanism capable of attaching to the long arm, wherein the attachment mechanism includes a fourth
blade, wherein the attachment mechanism comprises a first short arm and a second short arm, wherein the first short arm is
independent from the second short arm such that the attachment mechanism can be provided at different angles relative to the
retractor frame, wherein the entire attachment mechanism is attached to the long arm via a single clamp, wherein the long
arm has a first end and a second end, wherein an attachment portion connected to the first short arm and the second short
arm is capable of attaching to the long arm in a portion between the first end and the second end.

US Pat. No. 9,066,765

ORTHOPEDIC PLATING ASSEMBLY FOR BONE FIXATION AND SUBSIDENCE

Globus Medical Inc., Aud...

1. A method for installing an orthopedic plate assembly for bone fixation comprising:
placing an orthopedic plate at or near an area of treatment, the orthopedic plate having an upper surface, a lower surface,
and at least one opening that extends between the upper surface and the lower surface configured and dimensioned to receive
an orthopedic anchor, a first blocking member including a cut-out portion, the first blocking member having a blocking position
and a non-blocking position, the first blocking member being rotatable from the non-blocking position to the blocking position,
wherein in the non-blocking position, the cut-out portion is configured to face the orthopedic anchor and in the blocking
position, the cut-out portion is configured to face away from the orthopedic anchor, and a second blocking member removably
connected to the orthopedic plate and positioned to cover at least a portion of the opening, wherein the second blocking member
rests above an uppermost surface of the orthopedic plate; and

installing at least one orthopedic anchor through the at least one opening from an uninstalled position to an installed position
where the at least one orthopedic anchor engages the orthopedic plate and respective anatomy in the area of treatment, wherein
the orthopedic anchor is able to pivot and laterally translate with respect to the orthopedic plate when in the installed
position, and wherein the first blocking member and the second blocking member cooperate to prevent the at least one orthopedic
anchor from uninstalling from the orthopedic plate when the first blocking member is in the blocking position, wherein the
second blocking member comprises a top surface, a bottom surface and sidewalls between the top surface and the bottom surface,
such that rotation of the first blocking member causes the orthopedic anchor to be bounded by a sidewall of the first blocking
member and the bottom surface of the second blocking member.

US Pat. No. 9,173,750

INSERTION TOOL ASSEMBLY

GLOBUS MEDICAL, INC., Au...

1. A surgical system comprising:
an insertion tool assembly for delivering an implant to a surgical site, wherein the insertion tool assembly comprises:
a handle assembly;
a sleeve assembly extending from the handle assembly; and
a gripping tip operably connected to the sleeve assembly, wherein the gripping tip comprises a proximal portion, a body and
a distal portion, wherein the distal portion comprises a first jaw portion and a second jaw portion, wherein the first jaw
portion includes a first recess formed therethrough and the second jaw portion includes a second recess formed therethrough,
wherein the gripping tip further comprises a first drill guide and a second drill guide that extend through the distal portion
of the gripping tip; and

an implant for delivery to the surgical site, wherein the implant comprises a spacer having a body formed of a top surface,
a bottom surface and an opening that extends through the top surface and the bottom surface, wherein a first portion of the
spacer is received within the first recess in the first jaw portion and a second portion of the spacer is received within
the second recess in the second jaw portion when the spacer is attached to the insertion tool assembly.

US Pat. No. 9,138,262

POLYAXIAL SCREW

GLOBUS MEDICAL, INC., Au...

1. A spine stabilization system comprising:
an elongate rod;
a bone fastener having a rounded head;
a coupling element comprising a coupling body and a cap;
wherein the coupling body comprises sidewalls that define two upwardly extending arms which define two slots capable of receiving
the elongate rod;

wherein the coupling body and cap interact to capture the elongate rod in the coupling body, wherein a first and second protrusions
configured on opposing sides of the cap and extending in a radial direction and a first and second recess configured in the
two upwardly extending arms extending in a radial direction and wherein the first and second protrusions are configured and
dimensioned to engage the first and second recess to limit movement of the cap with respect to the coupling body, when the
cap is rotated from a first position to a second position,

wherein the cap having a threaded opening for receiving a threaded locking element, the locking element capable of securely
holding the elongated rod in a fixed position relative to the coupling element,

wherein the cap further comprises at least one rim which extends radially outward from the top end of the perimeter of the
cap,

wherein a first of the upwardly extending arms includes a third recess positioned between the first recess and the upper surface
of the first of the upwardly extending arms for receiving the at least one rim of the cap and a second of the upwardly extending
arms includes a fourth recess for receiving the at least one rim of the cap, the fourth recess positioned between the second
recess and the upper surface of the second of the upwardly extending arms and wherein the third recess extends along the length
of an inner surface of the first of the upwardly extending arms and the fourth recess extends along the length of an inner
surface of the second of the upwardly extending arms.

US Pat. No. 9,220,538

FLEXIBLE ELEMENT FOR SPINE STABILIZATION SYSTEM

Globus Medical, Inc., Au...

1. A flexible connection system for connecting a first vertebra with respect to a second vertebra, comprising:
an elongate body extending from a first end portion to a second end portion along a longitudinal axis, the first and second
end portions interconnected by and rigidly fixed to a flexible cord coupling member,

the elongate body comprising first and second attachment portions configured and dimensioned to attach to bone fasteners to
connect the elongate body between first and second vertebrae,

the elongate body further comprising first and second resilient members coaxial with the flexible cord coupling member, the
first resilient member positioned between the first end portion and the first attachment portion, and the second resilient
member positioned between the first attachment portion and the second attachment portion, and

a set screw received through at least one bone fastener, wherein the set screw is positioned downwardly into contact with
an upper surface of at least one of the first and second attachment portions,

wherein, when the first and second attachment portions are attached to the bone fasteners, the first attachment portion is
movable along the flexible cord coupling member and along the longitudinal axis relative to the second attachment portion,

wherein the first and second attachment portions compress the second resilient member therebetween when the first and second
attachment portions move towards each other, and wherein the first end and first attachment portion compress the first resilient
member therebetween when the first and second attachment portions move away from each other; and

wherein the first attachment portion has a first end section that covers in a longitudinal direction at least a portion of
the second resilient member to inhibit relative motion between the first attachment portion and the second resilient member
in a direction transverse to the longitudinal axis,

wherein the flexible cord coupling member extends through an opening in the first end portion, the first end portion spaced
apart from a bone fastening member and the first end portion comprising a flange and a shoulder portion extending from the
flange along a longitudinal axis of the first end portion, the flange having a greater outer diameter than the shoulder portion,
and the shoulder portion is receivable within the first resilient member.

US Pat. No. 9,066,809

METHOD FOR INSERTING AND POSITIONING AN ARTIFICIAL DISC

GLOBUS MEDICAL INC., Aud...

1. A method of inserting intervertebral prosthetic disc assemblies from a posterior approach comprising:
accessing an intervertebral space between adjacent vertebral bodies; and
positioning the intervertebral prosthetic disc between the adjacent vertebral bodies,
wherein the intervertebral prosthetic disc comprises:
a first endplate having a plurality of protrusions for attaching to a first adjacent vertebrae and an extension portion extending
towards a second adjacent vertebrae, the extension portion being spaced apart from a base of the first endplate when assembled;

a second endplate having a plurality of protrusions for attaching to the second adjacent vertebrae and an extension portion
extending towards the first adjacent vertebrae, the extension portion being spaced apart from a base of the second endplate
when assembled;

a resilient member having an upper portion and a lower portion;
a slider plate having an upper and lower surface positioned and enclosed within a first cavity in the upper portion of the
resilient member, wherein the upper surface of the slider plate is configured to a contact a lower surface of the extension
portion of the first end plate; and,

wherein the extension portion of the first endplate is adapted to fit within the first cavity in the upper portion of the
resilient member and the extension portion of the second endplate is adapted to fit within a second cavity in the lower portion
of the resilient member,

wherein the extension portion of the first endplate engages with the upper surface of the slider plate to allow translation
or rotation of the extension portion relative to the slider plate,

wherein a length of the extension portion of the first endplate is smaller than a length of the slider plate.
US Pat. No. 9,138,508

BONE GRAFT MATERIALS DERIVED FROM MINERALIZED GELATIN

Globus Medical, Inc., Au...

1. A method for making a demineralized bone matrix product, comprising
separating a bone lot into a first portion and a second portion;
processing the first portion to create dried demineralized bone matrix;
extracting a mineralized gelatin solution comprising solubilized minerals from bone from the second portion;
converting the mineralized gelatin solution to a mineralized gelatin; and
combining the dried demineralized bone matrix with the mineralized gelatin to form a demineralized bone matrix product.

US Pat. No. 9,345,517

PEDICLE SCREW HAVING A REMOVABLE ROD COUPLING

Globus Medical, Inc., Au...

1. A pedicle screw for spinal fixation comprising:
a bone fastener portion, wherein the bone fastener portion is at least partially threaded;
a permanent rod coupling comprising a bottom surface connected to the bone fastener portion, a middle section positioned between
the bottom surface and a top surface, a lateral rod opening in a portion of the middle section adapted to receive a permanent
rod, wherein the lateral rod opening is on a side of the pedicle screw, a threaded bore that extends from the top surface
into the lateral rod opening, a permanent rod fastener mated to fit the threaded bore to extend into the lateral rod opening,
wherein the permanent rod fastener can engage a permanent rod positioned in the lateral rod opening, and a transition region
on a portion of the top surface;

a notched breakaway portion in the transition region;
a temporary rod coupling connected to the transition region, wherein the temporary rod coupling comprises a temporary rod
channel adapted to receive a temporary rod, an upper threaded opening that extends into the temporary rod channel, and an
upper rod fastener mated to the upper threaded opening, wherein the upper rod fastener can engage a temporary rod positioned
in the temporary rod channel;

wherein a permanent rod is positioned in the lateral rod opening and secured by the permanent rod fastener, a temporary rod
is temporarily positioned substantially parallel to the permanent rod in the temporary rod channel and secured by the upper
rod fastener, and when the temporary rod is not needed, a notch in the breakaway portion is capable of breaking to cause a
separation of the temporary rod coupling at the transition region to leave the top surface; and

wherein the bone fastener portion, the permanent rod coupling, the transition region, and the temporary rod coupling are of
a unitary construction, and aligned and parallel along a longitudinal axis of the pedicle screw.

US Pat. No. 9,168,067

CONNECTION ASSEMBLY

GLOBUS MEDICAL INC., Aud...

1. An orthopedic connection assembly comprising:
a housing member including a first aperture for receiving a securing member and a second aperture for receiving a spinal implant;
a plate member insertable into the housing member through a third aperture;
an interference member capable of engagement by the plate member;
a receiving member for receiving the interference member therein, the receiving member including a receiving aperture for
receiving an anchor member therethrough; and

a cap member receivable over the receiving member and mateable with the housing member,
wherein the assembly is configured to allow for a number of variable angles between the spinal implant and the anchor member.

US Pat. No. 9,186,159

DISCECTOMY INSTRUMENT

Globus Medical, Inc., Au...

11. A discectomy instrument for removing a portion of an intervertebral disc, comprising:
a rotary scraper;
a drive shaft operably attached to the rotary scraper;
an outer sleeve for coaxially receiving the drive shaft; a ball joint coupled to the rotary scraper at one end and to the
drive shaft at the other end, wherein the rotary scraper is pivotably connected to the ball joint; and

a barrel, wherein the drive shaft is removably connected to the barrel and capable of transmitting torque, and wherein the
rotary scraper is configured to pivot as well as rotate with the drive shaft.

US Pat. No. 9,072,547

POLYAXIAL CROSS CONNECTOR

GLOBUS MEDICAL, INC., Au...

1. A device for coupling first and second elongate spinal fixation elements, the device comprising:
a first connector member having proximal and distal portions, the distal portion including an engagement portion configured
and dimensioned to provisionally receive the first elongate spinal fixation element with an interference fit;

a translation member having proximal and distal portions, the proximal portion of the first connector member operatively associated
with the proximal portion of the translation member to provide polyaxial movement of the first connector member relative to
the translation member, wherein the proximal portion of the first connector member extends through a bore formed in the translation
member;

a second connector member having proximal and distal portions, the distal portion configured and dimensioned to receive the
second elongate spinal fixation element and the proximal portion coupled to the translation member; and

a first locking member to secure the first elongate spinal fixation element in the engagement portion of the first connector
member and to lock the polyaxial movement, thereby fixing the first connector member relative to the first translation member,
wherein the first locking member is received through the first connector and not the translation member.

US Pat. No. 9,226,836

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. An intervertebral implantation system comprising:
a fusion device capable of expansion and contraction, wherein the fusion device comprises:
a first endplate;
a second endplate;
a body portion that extends along at least a length of the first endplate and the second endplate, wherein the first endplate
and the second endplate move relative to the body portion; and

a translation member in between the first endplate and second endplate, wherein the translation member includes surfaces for
engaging the first endplate and second endplate to cause a change in a distance of separation between the first endplate and
second endplate; and

an instrument for engaging the body portion;
wherein two first surfaces of the translation member engage the first endplate and two second surfaces of the translation
member engage the second endplate,

wherein the two first surfaces of the translation member are spaced apart along the longitudinal axis of the fusion device
and each of the first surfaces are contained in separate planes parallel to one another and sloping towards the longitudinal
axis of the fusion device; and wherein the two second surfaces of the translation member are spaced apart along the longitudinal
axis of the fusion device and each of the second surfaces are contained in separate planes parallel to one another and sloping
towards the longitudinal axis of the fusion device.

US Pat. No. 9,144,438

ADJUSTABLE ROD DEVICES AND METHODS OF USING THE SAME

GLOBUS MEDICAL, INC., Au...

1. A medical device, comprising:
a first elongate member defining a first and a second interior region; and
a second elongate member configured to be coupled to a second anatomical structure within the body of the patient, wherein
the first interior region is enclosed to retain a portion of the second elongate member,

the first elongate member and the second elongate member having a first configuration in which the first elongate member and
the second elongate member have a first length when the portion of the second elongate member is disposed within the first
interior region of the first elongate member,

wherein the first elongate member and the second elongate member can be moved from the first configuration to a second configuration
in which the first elongate member and the second elongate member have a second length different than the first length, and

a volume of fluid is disposed within only the first interior region of the first elongate member, the volume of fluid configured
to at least partially control the movement of the first elongate member and the second elongate member between the first configuration
and the second configuration.

US Pat. No. 9,125,757

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. A method of installing intervertebral implants, the method comprising:
placing more than one intervertebral implant into an intervertebral disc space, each intervertebral implant comprising:
a first endplate having a first end and a second end, the first endplate comprising a first side portion and a second side
portion;

a second endplate having a first end and a second end, wherein the first end of the second endplate is configured to fit over
the second end of the first endplate, wherein the first end of the first endplate is configured to fit over the second end
of the second endplate, the second endplate comprising a first side portion and a second side portion;

a central ramp having a first end and a second end, the central ramp comprising:
a bore extending through the central ramp;
a first expansion portion at the first end of the central ramp, the first expansion portion comprising a first side portion
and a second side portion;

an extension, the extension extending from the first expansion portion to the second end of the central ramp;
a second expansion portion located on the extension between the first end and the second end of the central ramp; and
a driving ramp;
rotating the actuator assembly of at least one of the implants in a first direction to expand the intervertebral implant such
that the implants are implanted at different heights; and

wherein in at least one of the implants:
the first and second side portions of the first endplate comprise first ramped surfaces proximate the first end of the first
endplate, and wherein the rotation of the actuator assembly causes first ramped surfaces in the first and second side portions
of the first expansion portion of the central ramp to push against the first ramped surfaces in the first and second side
portions of the first endplate to push the first endplate outwardly;

the first and second side portions of the second endplate comprise second ramped surfaces proximate the second end of the
second endplate, and wherein the rotation of the actuator assembly causes second ramped surfaces in the first and second side
portions of the central ramp to push against the second ramped surfaces in the first and second side portions of the second
endplate to push the second endplate outwardly;

the first and second side portions of the second endplate comprise first ramped surfaces proximate the first end of the second
endplate, and wherein rotation of the actuator assembly causes ramped surfaces in the first and second side portions of the
driving ramp to push against the first ramped surfaces in the first and second side portions of the second endplate to push
the second endplate outwardly;

the first and second endplates comprise central ramped surfaces between the first end and the second end of the first and
second endplates, and wherein rotation of the actuator assembly causes ramped surfaces in the second expansion portion to
push against the central ramped surfaces in the first and second endplates to push the first and second endplates outwardly.

US Pat. No. 9,186,263

IMPLANT INSERTER

Globus Medical, Inc., Au...

1. A method for inserting an implant between vertebrae, comprising the steps of:
accessing an area between vertebrae;
providing an instrument comprising:
a body having a through bore;
a tubular portion received in the body, wherein the tubular portion comprises at least one window;
a central shaft movable within the through bore, the central shaft having a proximal end and a distal end;
a pair of distractor arms having proximal portions and distal portions, the proximal portions pivotally coupled to the body
and distal portions for engagement between the vertebrae;

tracking slots formed in and extending through surfaces of and along a longitudinal axes of the distractor arms;
an attachment tip operably connected to the central shaft, the attachment tip configured to grip the implant;
a rotatable dial configured to control engagement and disengagement of the implant to the attachment tip; and
a single guide member projecting outward from the attachment tip, wherein the attachment tip is removably connectable to the
central shaft in multiple configurations;

positioning the instrument to distract the adjacent vertebrae;
positioning an implant between the adjacent vertebrae; and
releasing the implant from the instrument.

US Pat. No. 9,254,152

DEROTATION APPARATUS FOR TREATING SPINAL IRREGULARITIES

GLOBUS MEDICAL, INC., Au...

1. An apparatus for treating spinal irregularities, comprising:
a derotation apparatus comprising:
a tube assembly comprising an inner sleeve and an outer sleeve disposed over the inner sleeve, wherein the inner sleeve has
a distal end for attachment to an implant;

a handle assembly; and
a ball joint assembly disposed between the tube assembly and the handle assembly, wherein the ball joint assembly comprises:
a ball joint configured for attachment to a coupling rod, wherein the ball joint comprises an upper portion and a lower portion
that match together to form a rotatable ball;

an outer washer having a serrated surface configured to prevent rotation of the ball by engaging an outer surface of the ball
when the ball joint is in a locked position; and

an inner washer fit within the outer washer and having a protruding rim with a smooth surface, and wherein the protruding
rim is configured to extend through the outer washer to engage an outer surface of the ball without preventing rotation of
the ball when the ball joint is in an unlocked position.

US Pat. No. 9,220,554

METHODS AND APPARATUS FOR TREATING VERTEBRAL FRACTURES

Globus Medical, Inc., Au...

1. A method for treating a bone comprising:
inserting a cannula having an inner lumen into the bone;
creating a cavity in the bone;
providing a containment assembly comprising:
a tubular member having a proximal end and a distal end,
a containment jacket disposed on the distal end of the tubular member, and
a guide wire disposed through the tubular member with the guide wire extending into the containment jacket;
inserting the containment jacket through the inner lumen of the cannula and into the cavity;
inserting a balloon into the containment jacket after insertion of the containment jacket into the cavity and inflating the
balloon; and

introducing a filler material directly in contact with the containment jacket, wherein the filler material is introduced into
the containment jacket while the balloon is inflated,

wherein the containment jacket is an expandable implant, and
wherein the containment jacket has a proximal end and a distal end, wherein the proximal end of the containment jacket is
closer to the distal end of the tubular member than the distal end of the containment jacket, wherein the balloon is inflated
near the proximal end of the containment jacket.

US Pat. No. 9,402,739

VARIABLE LORDOSIS SPACER AND RELATED METHODS OF USE

Globus Medical, Inc., Au...

1. An expandable fusion device comprising:
a first endplate having an upper surface defining a first plane extending from a first side of the expandable fusion device
to a second side of the expandable fusion device;

a second endplate having a lower surface defining a second plane extending from the first side of the expandable fusion device
to the second side of the expandable fusion device;

a first ramp configured to mate with both the first and second endplates, wherein the first ramp is a wedge with an incline
extending along a longitudinal axis of the expandable fusion device, and is also a wedge having an incline extending along
a lateral axis of the expandable fusion device; and

a second ramp configured to mate with both the first and second endplates, wherein the second ramp is a wedge having an incline
extending along the longitudinal axis of the expandable fusion device, and is also a wedge having an incline extending along
the lateral axis of the expandable fusion device

wherein the expandable fusion device is moveable between a collapsed configuration and an expanded configuration, and
wherein in the collapsed configuration the first plane and second plane are non-parallel.

US Pat. No. 9,271,762

OFFSET VARIABLE ANGLE CONNECTION ASSEMBLY

Globus Medical, Inc., Au...

1. A system for securing a spinal implant to a bone anchor, the system comprising:
an anchor configured to be implanted into a vertebral body;
a spinal implant; and
a connection assembly comprising a housing member and a receiving member, the housing member having a first end and a second
end, the housing member having an aperture proximate the first end for receiving a portion of the spinal implant, and the
receiving member having a first end and a second end, the receiving member having an aperture for receiving a portion of the
anchor and a resilient leg for contacting the anchor, wherein the receiving member is rotatably connected to the housing member,

wherein the connection assembly further comprises a connection member having a first end and a second end, the connection
member having a lumen, the lumen is in fluid communication with the aperture of the housing member and oriented generally
transversely to the aperture of the housing member, the second end of the connection member is received in a channel of the
housing member so that the connection member is rotatably and translatably connected to the housing member.

US Pat. No. 9,179,940

SYSTEM AND METHOD FOR REPLACEMENT OF SPINAL MOTION SEGMENT

GLOBUS MEDICAL, INC., Au...

1. A spine stabilization system for flexibly stabilizing a first vertebra with respect to a second vertebra, the system comprising:
an end member, a resilient member, a first attachment portion, an intermediate portion, and a second attachment portion interconnected
by a flexible coupling member along a longitudinal axis, wherein the resilient member is positioned between the end member
and the first attachment portion, and the intermediate portion is positioned between the first attachment portion and the
second attachment portion,

wherein the first attachment portion is movable along the longitudinal axis of the flexible coupling member such that the
resilient member is configured to be resiliently compressed between the first attachment portion and the end member when the
first attachment portion and second attachment portion extend away from one another, and the intermediate portion is configured
to be resiliently compressed between the first attachment portion and the second attachment portion when the first attachment
portion and second attachment portion move toward one another,

wherein the first attachment portion is a floating spool and the second attachment portion is a locking spool, the floating
spool and the locking spool each comprise an extended side wall extending in a direction along the longitudinal axis and capable
of contacting each other to provide for controlled motion.

US Pat. No. 9,480,579

EXPANDABLE INTERVERTEBRAL IMPLANT

GLOBUS MEDICAL, INC., Au...

1. A surgical method comprising:
forming an incision in a patient;
removing tissue from the patient at a surgical site;
inserting an expandable implant into the surgical site; and
expanding the expandable implant at the surgical site,
wherein the expandable implant comprises an upper endplate, a lower endplate, a moveable actuator positioned therebetween,
and a rotatable actuator screw configured to actuate the moveable actuator,

wherein the expandable implant further comprises a first bone fastener insertable through a first through hole in the upper
endplate and a second bone fastener insertable through a second through hole in the lower endplate, wherein the first through
hole is part of a socket that is partially formed in the upper endplate and partially formed in the lower endplate.

US Pat. No. 9,393,128

EXPANDABLE VERTEBRAL PROSTHESIS

GLOBUS MEDICAL, INC., Au...

1. An expandable implant device comprising:
an inner member having a generally cylindrical body and an outer member having a generally cylindrical body and a hollow interior
portion, wherein the inner member is telescopingly received within the outer member; and

a gear member having a hollow body extending from a distal end to a proximal end, an exterior wall, and an array of gear teeth
positioned along a periphery of the exterior wall on the proximal end, wherein the gear teeth are positioned at an angle with
respect to the proximal end, and the gear member being configured to effect translation of the inner member with respect to
the outer member,

wherein the outer member comprises a plurality of slits extending through an exterior wall of a distal end of the outer member,
and the distal end of the outer member is cooperatively engaged with the gear member.

US Pat. No. 9,326,799

METHODS AND APPARATUS FOR TREATING VERTEBRAL FRACTURES

GLOBUS MEDICAL, INC., Au...

1. A containment assembly for treating bone, comprising:
a containment jacket adapted to be deployed inside bone;
a balloon adapted to be positioned inside the containment jacket;
a dividing wall that separates the interior of the containment jacket into a proximal region and a distal region, the dividing
wall having an opening for providing access to the distal region from the proximal region;

a tubular member having a proximal end and a distal end, wherein the distal end is coupled to the containment jacket;
filler material insertable into the containment jacket, wherein the dividing wall separates the filler material from the balloon,
and

an inner lumen extending through the balloon for delivering the filler material to the distal region of the containment jacket,
wherein the containment jacket comprises a longitudinal axis along which the inner lumen extends therethrough, wherein the
dividing wall extends in a direction from an upper surface of the containment jacket down towards the inner lumen and from
the inner lumen down towards a lower surface of the containment jacket.

US Pat. No. 9,326,861

STABILIZING JOINTS

GLOBUS MEDICAL, INC., Au...

1. A device for separating and stabilizing first and second adjacent vertebrae together defining an intervertebral space between
them, the device comprising:
a plate comprising a plurality of sockets each configured for retaining a fastener passable through the socket and into the
first or second vertebral body, and one or more connecting projections extending from a side of said plate;

a spacer body having an upper surface and a lower surface sized and dimensioned to be contained within the intervertebral
space and the upper surface engageable with the first vertebral body, and the lower surface engageable with the second vertebral
body,

a plurality of teeth projecting from at least one of said upper or lower surface,
a chamber formed by an opening extending between said upper and lower surfaces, one or more connecting projections of the
spacer body mateable with said one or more connecting projections of said plate to thereby securely mutually connect said
plate and said spacer body, and

a fastener extending through the plate for engaging a vertebral body, wherein the fastener comprises a head and a body that
extends along a straight longitudinal axis,

wherein one or more connecting projections of the plate are configured with an upper surface and a lower surface and extend
rearward and the upper surface is configured and dimensioned to contact the first vertebral body

wherein the upper surface of the spacer body is defined by a plane, and a portion of the head of the fastener extends above
the plane of the upper surface.

US Pat. No. 9,301,851

TRANSFORAMINAL PROSTHETIC SPINAL DISC APPARATUS

GLOBUS MEDICAL, INC., Au...

1. An implant for positioning between adjacent vertebral bodies comprising:
a first endplate having a first surface configured to substantially engage a first vertebral body, the first endplate including
a first keel; and

a second endplate having a second surface configured to substantially engage with a second vertebral body, the second endplate
including a second keel,

wherein the second endplate includes a first window and an opposing second window,
wherein a portion of the first endplate directly contacts a surface of the second endplate and is retained within the first
and second windows of the second endplate.

US Pat. No. 9,408,640

VARIABLE ANGLE CONNECTION ASSEMBLY

GLOBUS MEDICAL, INC, Aud...

1. A connection assembly for connecting a spinal implant to an anchor, the connection assembly comprising:
a housing member having a first end and a second end, the housing member having an aperture proximate the first end for receiving
a portion of a spinal implant and a channel extending from the second end towards the first end, the channel is in fluid connection
with the aperture and oriented generally transversely to the aperture;

a receiving member having a first end and a second end, the receiving member having an aperture proximate the first end for
receiving a portion of an anchor and a lumen extending from the second end towards the first end, the lumen is in fluid communication
with the aperture and oriented generally transversely to the aperture, the second end of the receiving member is received
in the channel so that the receiving member is rotatably and translatably connected to the housing member;

a cap member having a lumen and an extension portion, wherein the channel of the housing member receives the extension portion
of the cap member, and

an annular member having a first face and a second face, the annular member positioned over the receiving member and received
in the channel, wherein the receiving member has a rim portion having at least one ridge proximate the second end, wherein
the second face of the annular member has at least one ridge, and wherein the at least one ridge on the rim portion faces
the at least one ridge on the second face of the annular member.

US Pat. No. 9,211,144

SPINE SURGERY DEVICE AND METHOD

GLOBUS MEDICAL, INC., Au...

1. A cross connector system for use in spine surgery, the system including:
a first rod extending longitudinally along a spine;
a second rod extending longitudinally along the spine;
a cross connector comprising:
first and second hooks each having a throat partially defined by a respective shanks, said throats receiving the respective
first rod and second rod, said throats each including an opening generally facing toward one another;

a flexible connector secured to the first hook and extending to the second hook, said first and second hooks each including
a passage for receiving the flexible connector; and

a rigid connector secured to and extending between the first and second hooks to fix a distance of separation between the
first hook and the second hook,

wherein the cross-connector extends generally perpendicularly to the first and second rods
wherein the flexible connector includes a first end and a second end, the second end configured as a free end that extends
beyond the shank and configured to receive a tool for tensioning

wherein the rigid connector having a pair of fingers on opposite ends thereof with each pair of fingers having a channel therebetween
for receiving a respective said hook shank therein.

US Pat. No. 9,301,850

EXPANDABLE VERTEBRAL IMPLANT

GLOBUS MEDICAL, INC., Au...

1. An expandable prosthetic implant for engagement between vertebrae, comprising:
an inner member having a hollow interior portion and an external portion, the inner member comprising a longitudinal groove
extending along a length of the inner member;

a first endplate configured to engage a first vertebral body connected to the inner member;
an outer member having a hollow interior portion configured to coaxially receive the inner member therein, wherein the inner
and outer members are moveable relative to each other along a longitudinal axis from a first position to a second position;

a pin having a first end and a second end, the pin extending through the outer member, and the second end configured to engage
the groove in the inner member when the inner and outer members are in the first position and the second end does not engage
the groove in the inner member when the inner and outer members are in the second position;

a gear member positioned coaxial to the inner member and outer member and axially fixed to the outer member; and
a second endplate configured to engage a second vertebral body connected to the outer member.

US Pat. No. 9,283,015

DELIVERY OF APPARATUS AND METHODS FOR VERTEBROSTENTING

Globus Medical, Inc., Au...

1. A surgical method comprising:
creating a pathway to a vertebral body;
forming a curved pathway in the vertebral body using a curved drill;
enlarging the curved pathway to form an enlarged cavity in the vertebral body using a reamer;
inserting a stent via a stent delivery system into the enlarged cavity, wherein the stent delivery system comprises a sheath
extended over the stent, wherein the stent comprises a co-braided structure that is self-expandable and collapsible within
the sheath; and

removing the sheath from the stent to deploy and expand the stent, wherein the stent expands on its own within the vertebral
body without the use of a filler material, and simultaneously moving forward the stent to compensate for any foreshortening
of the stent during removal of the sheath.

US Pat. No. 9,138,330

INTERVERTEBRAL SPACER

Globus Medical, Inc., Au...

1. An assembly for implant installation between adjacent vertebral bodies of a patient, comprising:
an implant having a proximal end portion, a distal end portion, a first curved lateral wall extending from the proximal end
portion to the distal end portion, and a second curved lateral wall extending from the proximal end portion to the distal
end portion;

wherein the implant includes a superior surface and an inferior surface, wherein at least one of the superior surface and
inferior surface include a plurality of protrusions to facilitate prevention of expulsion of the implant once installed;

wherein the implant defines an opening extending from the superior surface to the inferior surface and positioned between
the proximal end portion and the distal end portion;

wherein the implant includes an engagement surface at the proximal end; and an installation instrument removably attached
to the proximal end portion of the implant and engageable with the engagement surface to selectively permit rotation between
the instrument and the implant, the installation instrument extending along a longitudinal tool axis, wherein the installation
instrument includes a first prong, a second prong, a first tong and a second tong, wherein the first tong is located laterally
outwardly from at least a portion of an outer side surface of the first prong and the second tong is located laterally outwardly
from at least a portion of an outer side surface of the second prong,

wherein the installation instrument includes a first position and a second position, wherein in the first position at least
a portion of the installation instrument is distally closer to the distal end portion of the implant than in the second position,
wherein in the first position the implant is rotationally fixed with respect to the instrument and in a second position the
implant is rotatable with respect to the instrument.

US Pat. No. 9,078,685

METHOD AND SYSTEM FOR PERFORMING INVASIVE MEDICAL PROCEDURES USING A SURGICAL ROBOT

GLOBUS MEDICAL, INC., Au...

1. A system for performing an invasive medical procedure, comprising:
a robot comprising:
an instrument;
an effectuator element, the effectuator element configured to securely hold the instrument at a desired position;
a motor assembly that is configured to move the effectuator element in each one of the x, y and z directions; and
a control unit that is operatively coupled to the robot,
wherein the control unit is configured to transmit signals to the robot to cause the motor assembly to selectively move the
effectuator element along the x, y and z directions, the control unit being configured (i) to calculate a position of a transmitter
affixed to the instrument by analysis of signals emitted by the transmitter (ii) display a position of the instrument with
respect to a patient's body based on the calculated position of the transmitter and (iii) to control actuation of the motor
assembly

wherein the transmitter is affixed at a desired location of the instrument and the control unit is configured to selectively
energize the transmitter to ablate tissue and cause at least a portion of the instrument to move in a desired direction.

US Pat. No. 9,339,394

LINKED BILATERAL SPINAL FACET IMPLANTS AND METHODS OF USE

GLOBUS MEDICAL, INC, Aud...

1. An implantable system comprising:
a superior facet prosthesis, wherein the superior facet prosthesis comprises:
a flange portion;
a first opening extending through the flange portion for receiving a fixation element therethrough, and
a facet articulating component configured to articulate relative to an inferior facet, and
an inferior facet prosthesis, wherein the inferior facet prosthesis comprises:
a longitudinal rod-like member that is placed over the superior facet prosthesis, and
a second opening extending through the inferior facet prosthesis, wherein the second opening is aligned with the first opening
to receive the fixation element therethrough;

a first flexible element for securing the superior facet prosthesis to bone; and
a second flexible element for securing the inferior facet prosthesis to bone.

US Pat. No. 9,283,003

ORTHOPEDIC CLAMP AND EXTENSION ROD

Globus Medical, Inc., Au...

1. A method of extending a pre-existing spinal implant construct including an elongated rod attached to a portion of the spine,
the method comprising:
providing an extension clamp including a monolithic yoke having a first end and a second end, the first end comprising first
and second rod engaging portions and a channel between the first and second rod engaging portions, the second end being spaced
apart from the first end, and an extension rod extending from the second end of the yoke;

positioning the extension rod substantially parallel to the elongated rod;
connecting the extension clamp to the elongated rod by engaging the first and second rod engaging portions of the yoke with
the elongated rod and securing first and second set screws extending through the first and second rod engaging portions, respectively,
to the elongated rod; and

attaching a fastener to another portion of the spine by positioning the fastener within the channel of the yoke between the
first and second rod engaging portions.

US Pat. No. 9,364,269

LATERAL SPINOUS PROCESS SPACER WITH DEPLOYABLE WINGS

GLOBUS MEDICAL, INC., Au...

1. A method of implanting a device between adjacent spinous processes comprising:
creating an incision in a patient to be treated;
dilating any interspinous ligaments in a position in which the device is to be placed in the patient;
sizing a space between adjacent spinous processes; and
inserting the device between the adjacent spinous processes in a first position, the device comprising:
an elongate body comprising a first end portion, a second end portion, and a central support portion disposed between the
first end portion and the second end portion;

wherein the first end portion comprises a wing member movable from the first position to a second position, the wing member
including an outer surface and an inner surface that faces a central longitudinal axis of the elongate body;

wherein in the first position, the wing member serves as a ramp to engage and separate the adjacent spinous processes; and
moving the device to the second position to expand the wing member such that a portion of the inner surface of the wing member
is capable of contacting a lateral surface of at least one of the spinous processes to limit movement of the device with respect
thereto,

inserting a guide wire laterally through the skin and into an interspinous space;
creating a working portal concentric to the guidewire by inserting a series of sequentially larger diameter tubes to dilate
the tissue surrounding the guidewire; and

once a dilating tube having a sufficiently large inner diameter to accommodate the device is positioned about the guidewire,
withdrawing the smaller diameter tubes, leaving the guidewire and the outer tube.

US Pat. No. 9,358,124

IMPLANT INSERTER

GLOBUS MEDICAL, INC., Au...

1. An apparatus for inserting an implant between vertebrae, comprising:
a body having a through bore and a first tubular portion and a second tubular portion;
wherein the second tubular portion comprises at least one window;
a central shaft movable within the through bore, the central shaft having a proximal end and a distal end;
a pair of distractor arms having proximal portions and distal portions, the proximal portions pivotally coupled to the second
tubular portion of the body and distal portions for engagement between the vertebrae;

tracking slots formed in and extending through surfaces of and along a longitudinal axes of the distractor arms;
an attachment tip operably connected to the central shaft, the attachment tip configured to grip the implant;
a rotatable dial configured to control engagement and disengagement of the implant to the attachment tip; and
a single guide member projecting outward from the attachment tip, wherein the attachment tip is removably connectable to the
central shaft in multiple configurations

wherein the second tubular portion is tapered.

US Pat. No. 9,232,971

CEMENT-DIRECTING ORTHOPEDIC IMPLANTS

GLOBUS MEDICAL, INC., Au...

12. A cement-directing device, comprising:
a compressible, shape-restoring hollow mesh structure having a compressed shape and an expended shape, wherein the compressed
shape is capable of being inserted into and moved through a cannula, the expanded shape being approximately football-shaped,
and the mesh structure having sufficiently open mesh area to create minimal added flow resistance to bone cement inserted
into the device, wherein said mesh structure itself has regions of differential permeability or flow resistance, and wherein
said mesh structure is a co-braided structure comprising primary members and secondary members occupying interstices between
said primary members, and

at least one baffle member attached to the hollow mesh structure and configured to direct the flow of bone cement in preferred
directions and to impede the flow of bone cement in non-preferred directions.

US Pat. No. 9,314,347

METHOD AND IMPLANT DEVICE FOR GRAFTING ADJACENT VERTEBRAL BODIES

Globus Medical, Inc., Au...

1. An implant device for grafting together adjacent bony structures of a body comprising:
an endplate having an inner disc portion and outer ring portion spaced from the inner disc portion by a connecting wall disposed
therebetween, wherein an interior surface of the endplate includes a retaining structure for securing the endplate to one
of the bony structures, and the endplate inner disc portion has an integrally formed socket;

a ball joint rod having a longitudinally extending body and an end, wherein at least a portion of the ball-joint rod end is
curvilinear in shape, and the curvilinear ball joint rod end is rotatably disposed in the endplate socket to fixedly interconnect
the bony structures; and

a fusion shaft member partially surrounding the body of the ball-joint rod, and the fusion shaft member includes a plurality
of outwardly extending extension members.

US Pat. No. 9,155,628

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. An intervertebral implant comprising:
a body portion comprising an anterior end, a posterior end, a first side portion connecting the anterior end and the posterior
end, and a second side portion connecting the anterior end and the posterior end, the anterior end, posterior end, first side
portion and second side portion defining a central opening;

an expandable member comprising a fixed end, an expandable end, a first arm, and a second arm, the first arm and the second
arm being connected at the fixed end, the first arm and the second arm being moveable with respect to one another at the expandable
end, wherein at least a portion of the expandable member is received within the central opening of the body portion;

a ramped translation member having a first expansion portion and a second expansion portion, wherein at least a portion of
the ramped translation member is received within the central opening, and at least a portion of the ramped translation member
is received within a channel defined between the first arm and the second arm of the expandable member;

an actuation member in engagement with the ramped translation member, wherein the actuation member is movable with respect
to the ramped translation member;

wherein the first expansion portion of the ramped translation member comprises one or more ramped surfaces for engaging corresponding
ramped surfaces on the first and second arms, and wherein the second expansion portion is in engagement with the actuation
member, the first

expansion portion and the second expansion portion being connected by a bridge portion, wherein movement of the ramped translation
member in a first direction causes the one or more ramped surfaces of the first expansion portion to push against the corresponding
ramped surfaces of the first arm and second arm; and wherein one or more screws are disposed through the anterior end of the
body portion

and into the first expansion portion of the ramped translation member.

US Pat. No. 9,155,631

INTERVERTBRAL IMPLANT

GLOBUS MEDICAL INC., Aud...

1. An intervertebral implant for implantation in a treated area of an intervertebral space between vertebral bodies of a spine,
wherein said implant comprises:
a spacer having, an inferior and superior surface, wherein the inferior and superior surfaces each have a contact area capable
of engaging with anatomy in the treated area, and the inferior and superior surfaces define a graft window extending from
the superior surface of the spacer to the inferior surface of the spacer;

a first screw hole extending from an anterior surface to the inferior surface of the spacer, and a second screw hole extending
from the anterior surface to the superior surface of the spacer;

a plate rigidly coupled to the spacer, wherein the plate includes screws holes for receiving screws; and
wherein a screw back out prevention mechanism is adapted on the plate and prevents the back out of screws from the screw holes,
wherein the posterior surface of the plate includes a first and second tongue that are configured to mate with a first and
a second groove of the spacer,

wherein the screw back out prevention mechanism includes a pin screw and a nut,
wherein the nut is configured to be positioned entirely within the graft window of the spacer,
wherein the graft window is configured to receive bone graft to enhance fusion between adjacent vertebrae.

US Pat. No. 9,486,251

SPINOUS PROCESS FIXATION SYSTEM AND METHODS THEREOF

Globus Medical, Inc., Au...

1. An implantable device, comprising:
a barrel, the barrel having an upper portion and a lower portion;
an actuator assembly disposed in the barrel, the actuator assembly comprising a front ramped actuator in engagement with the
barrel, a rear ramped actuator in engagement with the barrel, and a central screw that extends from the rear ramped actuator
through the front ramped actuator;

a first plate comprising a first portion that extends from the upper portion, a second portion that extends form the lower
portion, and a pivoting spike assembly disposed in the first plate, the pivoting spike assembly comprising multiple projections
extending from a first side of the first plate; and

a second plate having multiple projections extending from a first side of the second plate, the second plate configured to
be received on the central screw;

wherein the barrel is configured to transition from a collapsed form having a first height to an expanded form having a second
height and wherein the second height is greater than the first height,

wherein the front ramped actuator is positioned closer to the rear ramped actuator when the barrel is in the expanded form,
wherein the second plate comprises an upper portion, a lower portion, a central portion connecting the upper portion and the
lower portion, and a trunion assembly disposed in an opening in the central portion and

wherein the trunion assembly comprises a housing for receiving the central screw, a pair of chambers on either side of a through
bore, and a pair of ratchet pawls, each of the ratchet pawls being individually disposed in one of the chambers and configured
to engage the central screw in the through bore.

US Pat. No. 9,387,012

COUPLING DEVICES AND METHODS OF USING THE SAME

Globus Medical, Inc., Au...

1. A surgical method comprising:
providing a stabilization system, wherein the stabilization system comprises:
a top member;
a bottom member operably attached to the top member, wherein the bottom member includes a first slot and a second slot, wherein
the first slot includes a first opening extending therethrough and the second slot includes a second opening extending therethrough;
and

a set screw;
securing the stabilization system to one or more vertebrae;
inserting a first rod member into the first slot;
inserting a second rod member into the second slot; and
rotating the top member to secure the first rod member and the second rod member within the stabilization system,
wherein the first opening receives a first bone screw and the second opening receives a second bone screw.

US Pat. No. 9,095,387

SPINE STABILIZATION

GLOBUS MEDICAL, INC., Au...

1. A device for stabilizing bones of a patient, comprising:
a first plate portion having an upper surface configured to face away from body tissue of a patient and a lower surface configured
to face said body tissue of said patient including at least one aperture for receiving a first element to connect said first
plate portion to said body tissue of said patient;

a projection extending from said first plate portion;
a second plate portion including at least one aperture for receiving a second element to connect said second plate portion
to said body tissue of said patient;

a chamber formed in said second plate portion sized and dimensioned to receive said projection, thereby substantially limiting
movement of said first plate portion relative to said second plate portion to a motion in a first direction and in an opposite
second direction when said projection is received within said chamber;

a limiter resiliently extending from one of said projection or said chamber, wherein said limiter is bendable such that said
limiter is movable away from said upper surface of said first plate portion toward said lower surface of said first plate
portion;

a catch formed in said other of said projection or said chamber, relative to said limiter, operative to form an engagement
with said limiter, said catch further operative to admit passage of said limiter past said engagement when said first and
second plate portions are moved in said first direction, said catch further operative to prevent passage of said limiter past
said engagement of said catch and said limiter when said first and second plate portions are moved in said second direction

wherein said projection includes a spring relief formed therein, the spring relief receiving the limiter, the spring relief
having notched steps formed at opposite ends of said spring relief and a relief floor positioned at a depth greater within
said spring relief than said notched steps thereby allowing the limiter to rest upon the notched steps while the limiter is
engaged with the notched steps and permit the limiter to resiliently bend downwards towards the relief floor during use such
that the limiter releases from the notched steps when the limiter bends downwards towards the relief floor.

US Pat. No. 9,358,132

LINKED BILATERAL SPINAL FACET IMPLANTS AND METHODS OF USE

GLOBUS MEDICAL, INC., Au...

1. An implantable system comprising:
a superior member attachable to a bone member via a first fixation member;
an inferior member attachable to a bone member via a second fixation member, wherein the superior member and the inferior
member are configured to articulate relative to one another; wherein the inferior member comprises a ball-and-socket joint,

a stabilizing bar extending a length of the inferior member and adapted to attach to opposing ends of the inferior member,
wherein threaded ends of the stabilizing bar extend though flanges of the opposing ends of the inferior member, and
fasteners secure the threaded ends of the stabilizing bar by compressing the respective flanges around the stabilizing bar.

US Pat. No. 9,358,047

ORTHOPEDIC FIXATION DEVICES AND METHODS OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. A fixation system comprising:
a fastener including a shaft member and a head member; and
a tulip assembly attachable to the head member of the fastener, the tulip assembly including:
a tulip element including a pair of arms forming a channel for receiving a rod member therein;
a wedge element received in the tulip element;
a clamp element attachable to the wedge element, the clamp element including at least one opening for receiving one or more
portions of a ring element therein; and

a ring element having at least one protrusion for inserting into the at least one opening in the clamp element, wherein engagement
between the ring element and the clamp element converts the tulip assembly from a polyaxial assembly to a uniplanar assembly.

US Pat. No. 9,351,847

INTERBODY FUSION DEVICES WITH SELF-AFFIXING MECHANISMS

Globus Medical, Inc., Au...

1. An implant for implantation in a treated area of an intervertebral space between vertebral bodies of a spine, the implant
comprising:
a spacer having a superior surface and an inferior surface, the superior surface and the inferior surface each have a contact
area configured to engage adjacent vertebrae, and the spacer defines at least one opening extending from the superior surface
to the inferior surface;

at least one shaft coupled to the spacer and extending through the opening;
one or more fins operatively attached to the shaft; and
a wall extending through the spacer, wherein the wall divides the at least one opening in the spacer,
wherein rotation of the shaft causes deployment from a retracted position to a deployed position of the one or more fins,
the one or more fins configured to engage an adjacent vertebral body,

wherein the one or more fins rest on the wall dividing the at least one opening when in the retracted position but not in
the deployed position.

US Pat. No. 9,308,030

DEROTATION APPARATUS FOR TREATING SPINAL IRREGULARITIES

GLOBUS MEDICAL, INC., Au...

1. A method for treating a spinal irregularity:
providing a first derotation apparatus comprising a ball joint assembly having a first ball joint and a second ball joint
that articulates independently of the first ball joint;

providing a second derotation apparatus comprising a ball joint assembly;
coupling the first derotation apparatus to a first implant coupled to a vertebral body;
coupling the second derotation apparatus to a second implant coupled to a vertebral body;
aligning the ball joint assembly of the first derotation apparatus and the ball joint assembly of the second derotation apparatus
with one another;

coupling a first rod between one of the first and second ball joints of the ball joint assembly of the first derotation apparatus
and the ball joint assembly of the second derotation apparatus to interconnect the first derotation apparatus and the second
derotation apparatus; and

coupling a second rod to the other of the first and second ball joints of the ball joint assembly of the first derotation
apparatus,

wherein at least one of the first ball joint and the second ball joint of the first derotation apparatus comprises an upper
portion and a lower portion that match together to form a rotatable ball, the upper portion comprising a radially extending
upper tab, the lower -portion comprising a radially extending lower tab, and the upper tab and the lower tab forming a clamp for receiving the first
or second rod.

US Pat. No. 9,198,775

ARTIFICIAL SPINAL DISK PROSTHESIS

GLOBUS MEDICAL, INC., Au...

1. An intervertebral endoprosthesis disc for surgical implantation between two vertebrae comprising:
an endoprosthesis body comprising an anterior region and a posterior region designed to be positioned entirely between a first
vertebra and a second vertebra;

at least a first anterior cavity and a second anterior cavity positioned in the anterior region;
a first movable insert having a first fastener aperture and positioned rotatably in the first anterior cavity, wherein the
first movable insert is rotatable in the first anterior cavity; and

a second movable insert having a second fastener aperture and positioned rotatably in the second anterior cavity,
wherein the second movable insert is rotatable in the second anterior cavity independent of the first movable insert,
wherein the first and second movable inserts rotate in an axis transverse to a longitudinal axis of the endoprothesis body.

US Pat. No. 9,161,794

EXPANDING SPINAL ANCHOR

GLOBUS MEDICAL, INC., Au...

1. An anchor for a pedicle screw, the anchor comprising:
an anchor body comprising a proximal end, a proximal portion, a distal portion, and a distal end, wherein the distal portion
comprises a tapered outer body for insertion into a vertebra and a non-tapered outer body adjacent to the tapered outer body;

a through-hole extending through the anchor body from the proximal end to the distal end, the through-hole defining a long
axis of the anchor, the through-hole comprising undersized female threads in the proximal portion and a reduced inner diameter
in the distal portion, the reduced inner diameter configured to cause expansion of at least the distal portion of the anchor
body including the non-tapered outer body when the pedicle screw is inserted into the through-hole being advanced toward the
distal end, wherein the reduced inner diameter is formed by an inwardly tapered wall and is free of threads, wherein a portion
of the through-hole extends along a length of the tapered outer body and the non-tapered outer body and that portion of the
through-hole is non-threaded; and

a plurality of ridges on an exterior surface of the anchor body, the ridges configured to reduce the likelihood of pullout
when the anchor is inserted into a vertebra and the pedicle screw is inserted into the through-hole,

wherein expansion of the proximal portion of the anchor body is less than the expansion of the distal portion of the anchor
body,

wherein the proximal portion of the anchor body comprises a lip having one or more flat side surfaces that is configured to
restrict movement of the anchor body into a bone member.

US Pat. No. 9,226,831

INTERVERTEBRAL IMPLANT

GLOBUS MEDICAL, INC., Au...

1. An intervertebral spacer for therapeutic treatment of a patient, comprising:
at least one link having a body with a first opening extending from an upper surface to a lower surface sized and dimensioned
to fit within an intervertebral space in the patient and configured to maintain a separation of two adjacent vertebrae for
a period of time;

at least one rigid guiding object insertable into the patient, said at least one rigid guiding object and said at least one
link sized to be insertable into the patient using an MIS approach;

at least one pivot connected between an end of one of said at least one link and an end of one of said at least one rigid
guiding object, said at least one pivot configured to limit a relative range of angular orientation of said one of said at
least one link and said one of said at least one rigid guiding object, said at least one pivot configured to transfer an insertion
force from said at least one rigid guiding object to said at least one link, to advance said at least one link into the intervertebral
space,

a pivoting joint connected between adjacent links, and
a resilient catch, the resilient catch being configured to couple to a hook element provided in an adjacent link having a
body with a second opening therethrough, wherein the body with the first opening therethrough does not contact the body with
the second opening therethrough when the resilient catch is coupled to the hook element,

wherein the upper surface of the body is configured to contact one of the two adjacent vertebrae and the lower surface of
the body is configured to contact the other of the two adjacent vertebrae,

wherein the resilient catch bends to allow insertion of the hook element,
wherein the resilient catch and hook element are provided between the same adjacent links as the pivoting joint.

US Pat. No. 9,180,018

EXPANDABLE VERTEBRAL PROSTHESIS

GLOBUS MEDICAL, INC., Au...

1. An expandable prosthetic implant device for engagement between vertebrae, comprising:
an inner member having a hollow interior portion and a threaded external portion and including a first end portion configured
to engage a first vertebral body, the first end portion multi-axially articulatable with respect to the inner member;

an outer member having a hollow interior portion configured to coaxially receive the inner member therein and including a
second end portion configured to engage a second vertebral body, a second member including a second end portion configured
to engage a second vertebral body, the second end portion multi-axially articulatable with respect to the outer member, wherein
the inner and outer members are moveable relative to each other along a longitudinal axis;

a gear member positioned coaxial to the inner member and outer member and axially fixed to the outer member and freely rotatable
with respect to the outer member, wherein the gear member threadedly engages the threaded portion of the inner member,

a locking assembly having a flexible member positioned between the inner member and the outer member and movable between a
first position and a second position, and wherein in the first position one end of the flexible member engages with one of
a plurality of notches configured on the inner surface of the gear member to block movement of the gear member, and in the
second position the flexible member is disengaged from one of the plurality of notches and allows movement of the gear member
which allows relative movement between the inner member and the outer member

wherein the gear member includes gear teeth extending around the perimeter and configured to be accessible by a tool member
at a plurality of angular positions around the perimeter.

US Pat. No. 9,486,254

DEVICE AND METHOD FOR IMPLANTING A SPINOUS PROCESS FIXATION DEVICE

GLOBUS MEDICAL, INC., Au...

1. A method for installing an implant in an interspinous space, the method comprising:
providing an instrument comprising:
a main body;
a first arm; and
a second arm, wherein the first arm comprises a gripper and an associated gripper,
wherein the first and second arms are movably attached to the main body wherein the first and second arms are movably coupled
to the main body and configured to be moved along a longitudinal axis of the main body; and

installing the implant in the interspinous space using the instrument.

US Pat. No. 9,427,326

SPINAL IMPLANT

Globus Medical, Inc., Au...

1. A method of installing an intervertebral disc prosthesis in a spinal column, comprising:
inserting an intervertebral disc prosthesis into a disc space, the intervertebral disc prosthesis including:
a first intervertebral plate for engaging one or both of an inferior vertebral endplate and an inferior ring apophysis of
a superior vertebral body,

a second intervertebral plate for engaging one or both of a superior vertebral endplate and a superior ring apophysis of an
inferior vertebral body,

a gap located between the first and second intervertebral plates, and
a projection that projects from one of said intervertebral plates toward the other one of said intervertebral plates, wherein
the projection extends into an aperture formed in the other one of the said intervertebral plates, wherein the aperture is
sized and dimensioned to receive at least a portion of the projection;

inserting a removable insert core in the gap between the first and second intervertebral plates, the removable insert core
having a first upper surface that contacts the first intervertebral plate and a second lower surface that contacts the second
intervertebral plate; and

removing the removable insert core while the intervertebral plates remain installed in the disc space, wherein the projection
maintains proper spacing between the intervertebral plates while the insert core is removed.

US Pat. No. 9,408,709

INFLATABLE MULTI-CHAMBERED DEVICES AND METHODS OF TREATMENT USING THE SAME

Globus Medical, Inc., Au...

1. A surgical method comprising:
providing an implant, wherein the implant includes a deflated configuration and an inflated configuration whereby at least
a portion of the implant is expanded to a size greater than in the deflated configuration;

inserting the implant into a disc space of a patient in the deflated configuration; and
inflating the implant within the disc space of the patient,
wherein the implant comprises at least three chambers arranged side-by-side and a filling manifold for providing access to
at least one of the chambers in order to provide a filling material therein, and wherein the at least three chambers comprise
adjacent concentric hollow cylindrical tube chambers.

US Pat. No. 9,320,544

DYNAMIC SPINE STABILIZERS

GLOBUS MEDICAL, INC., Au...

1. A spine stabilization system, comprising:
a first bone fastener configured to attach the spine stabilization system to a first vertebra;
a second bone fastener configured to attach the spine stabilization system to a second vertebra;
a dynamic spine stabilizer configured to connect the first bone fastener and the second bone fastener with at least some relative
movement between the first bone fastener and the second bone fastener; and

a rod portion attachable to the dynamic spine stabilizer,
wherein when a force is applied to the dynamic spine stabilizer, the dynamic stabilizer is capable of sliding in lateral direction
along the rod portion and is capable of sliding in a direction generally perpendicular to the lateral direction.

US Pat. No. 9,149,365

LOW PROFILE PLATE

GLOBUS MEDICAL, INC., Au...

12. A spinal system comprising:
a spacer for inserting into an intervertebral space, the spacer including:
an upper surface,
a lower surface, and
an opening that extends between the upper surface to the lower surface;
a plate for abutting the spacer, the plate including:
a plate body,
a first opening formed in the plate body for receiving a first bone screw, wherein the first opening is angled in an upward
direction;

a second opening formed in the plate body for receiving a second bone screw, wherein the second opening is angled in a downward
direction; and

a pair of extensions that extend from the plate body, wherein the extensions are configured to engage outer sidewalls of the
spacer, and wherein each extension includes an enclosed window that extends along a length of the extension, wherein each
of the windows receives a hump portion that extends laterally outward from the outer sidewalls of the spacer;

a first bone screw for inserting into the first opening in the plate body, wherein the first bone screw is configured to be
inserted into a first vertebral body; and

a second bone screw for inserting into the second opening in the plate body, wherein the second bone screw is configured to
be inserted into a second vertebral body different from the vertebral body,

wherein the spacer and the plate are independent from one another such that the spacer can be inserted into a desired spinal
location prior to abutting the spacer with the plate.

US Pat. No. 9,370,434

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. An apparatus comprising:
a first endplate for an intervertebral implant having an upper surface, a lower surface, a first end and a second end, a length
along a longitudinal axis, the longitudinal axis extending from the first end to the second end,

wherein the first endplate further comprises a first side portion including a first ramped surface extending from the lower
surface proximate the first end, and a second ramped surface extending from the lower surface proximate the second end, and
a central ramped portion positioned between the first ramped surface and the second ramped surface, wherein the central ramped
portion has a first angled face that faces the first end of the first endplate and a second angled face that faces the second
end of the first endplate, wherein the first angled face and the second angled face are each at an oblique angle relative
to the longitudinal axis and extends along the length of the first endplate; and

a second endplate for the intervertebral implant having an upper surface, a lower surface, a first end and a second end, a
third ramped surface extending from the second upper surface of the second endplate proximate the first end, and a fourth
ramped surface extending from the second upper surface of the second endplate proximate the second end,

a central ramp positioned between the first endplate and the second endplate, the central ramp having a first end and a second
end, a first expansion portion, a second expansion portion, and a through bore extending from the first end to the second
end,

wherein the movement of the central ramp in one direction causes the first and second endplates to move apart and a movement
of the central ramp in a second direction causes the first and second endplates to move towards one another.

US Pat. No. 9,345,588

ANGLING INSERTER TOOL FOR EXPANDABLE VERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. A system for inserting an implant comprising:
an expandable implant configured for insertion into a patient's spine, the expandable implant having a longitudinal axis and
comprising a gear member configured to expand the expandable implant; and a tool having a longitudinal axis and configured
for insertion of the expandable implant between the vertebra, wherein the tool comprises:

a handle portion;
a cylindrical base portion coupled to the handle portion, wherein the cylindrical base portion comprises:
an outer cylinder;
an internal shaft configured to be coaxially received within the outer cylinder; a primary drive shaft configured to be coaxially
received within the internal shaft; and

a secondary drive shaft configured to be coaxially received within the primary drive shaft; and a tip assembly at a distal
end of the base portion, wherein the tip assembly comprises a base portion and a central shaft disposed in a through-bore
in the base portion of the tip assembly, wherein the central shaft is configured to engage the expandable implant;

a primary gear mechanism configured to transfer rotation of the primary drive shaft to the gear member on the expandable implant;
and a secondary gear mechanism configured to transfer rotation of the secondary drive shaft to the central shaft, wherein
the internal shaft is configured to engage the tip assembly such that the tip assembly is configured to rotate about a pin
coupled between the base portion of the tip assembly and the tip assembly upon distal advancement of the internal shaft.

US Pat. No. 9,198,772

ARTICULATING EXPANDABLE INTERVERTEBRAL IMPLANT

GLOBUS MEDICAL, INC., Au...

1. A spacer for separating bones of a joint, the spacer comprising:
a frame having a longitudinal axis, and having at least one ramped surface;
a first endplate configured to engage a first bone of the joint, and having at least one ramped surface mateable with the
at least one ramped surface of the frame, whereby when the first endplate is moved relative to the frame in a direction along
the frame longitudinal axis, the first endplate is moved in a direction away from the frame to increase a height of the spacer;

a second endplate configured to engage a second bone of the joint;
a link moveable with respect to the frame, the link having a projection engageable with the first endplate to thereby move
the first endplate along the frame longitudinal axis when the link is moved with respect to the frame;

an actuating screw moveable with respect to the frame and pivotally connected to the link to cause movement of the link when
the actuating screw is moved with respect to the frame; and

a nut threadably engaged with the actuating screw, the nut rotatable with respect to the frame to move the actuating screw
with respect to the frame.

US Pat. No. 9,375,238

ROTATABLE BONE PLATE

Globus Medical, Inc., Au...

1. A bone plate assembly for stabilizing at least two bony structures, comprising:
an elongate plate body having a plate portion and first and second integrated rod portions, the plate portion having first
and second ends, the elongate plate body having a longitudinal axis extending from the first end to the second end of the
plate portion, the first integrated rod portion extending in a first direction away from a center of the plate portion and
beyond the first end along a direction parallel to the longitudinal axis and the second integrated rod portion extending in
a second direction, opposite to the first direction, away from the center of the plate portion and beyond the second end along
a direction parallel to the longitudinal axis, the elongate plate body further comprising a first aperture and a second aperture,
the elongate plate body further comprising a fully enclosed first window and a fully enclosed second window, wherein the first
window is larger than the first aperture and the second window is larger than the second aperture;

a first bone fastener having a first receiving member and a second bone fastener having a second receiving member, wherein
the first receiving member captures the first integrated rod portion and the second receiving member captures the second integrated
rod portion of the elongate plate body, and

a first bone screw and a second bone screw, wherein the first bone screw is configured to be inserted into the first aperture
and the second bone screw is configured to be inserted into the second aperture,

wherein the first window and the second window extend from an upper surface of the elongate plate body to a lower surface
of the elongate plate body,

wherein along the longitudinal axis, the first window is offset from the first aperture and the second window is offset from
the second aperture.

US Pat. No. 9,408,641

SPINAL ROD LINK REDUCER

Globus Medical, Inc., Au...

1. A rod link reducer of a spinal fixation system comprising:
a first spinal rod manipulator having a first end that directly connects to a first spinal rod and having a second end that
forms a first extended handle;

a second spinal rod manipulator having a first end that directly connects to a second spinal rod and having a second end that
forms a second extended handle;

a first spinal rod manipulator joint directly connected to the first spinal rod manipulator between the first end of the first
spinal rod manipulator and the first extended handle of the first spinal rod manipulator;

a second spinal rod manipulator joint directly connected to the second spinal rod manipulator between the first end of the
second spinal rod manipulator and the second extended handle of the second spinal rod manipulator;

a first translatable transverse shaft having a first end directly connected to the first spinal rod manipulator joint;
a second translatable transverse shaft having a first end directly connected to the second spinal rod manipulator joint; and
a reducer directly connected to a second end of the first translatable transverse shaft and directly connected to a second
end of the second translatable transverse shaft, wherein the first translatable transverse shaft and the second translatable
transverse shaft are translatable relative to the reducer, wherein the reducer comprises a ball bearing mechanism that accommodates
angulation between the first translatable transverse shaft and the second translatable transverse shaft, and wherein the reducer
and the first translatable transverse shaft and the second translatable transverse shaft and the first spinal rod manipulator
and the second spinal rod manipulator provide movement and temporary fixation of the first spinal rod and the second spinal
rod.

US Pat. No. 9,554,918

ARTICULATING EXPANDABLE INTERVERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. An implant for separating bones of a joint, the implant comprising:
a first endplate having an upper surface and a lower surface, the upper surface configured to engage a first vertebral body,
and at least one ramped surface extending from the lower surface;

a second endplate having an upper surface and a lower surface, the lower surface configured to engage a second vertebral body,
and at least one ramped surface extending from the upper surface;

a body portion extending from a first end to a second end and positioned between the first and second endplates, the body
portion coupled to the first and second endplates;

an articulating element coupled to the body portion; and
a translation member positioned within the body portion, wherein when the translation member is moved from a first position
to a second position, the first and second endplate move apart from one another

wherein the articulating element attaches to the body portion through a curved dovetail connection, and the articulating element
translates within the body portion along a path on a vertebral facing surface defined by the dovetail connection.

US Pat. No. 9,351,848

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. An intervertebral implant comprising:
an upper endplate comprising a first upper endplate portion and a second upper endplate portion;
a lower endplate comprising a first lower endplate portion and a second lower endplate portion;
a front sloped actuator configured to movingly engage a front end of the upper endplate and a front end of the lower endplate,
the front sloped actuator comprising a front height actuator and a front width actuator; and

a rear sloped actuator configured to movingly engage a rear end of the upper endplate and a rear end of the lower endplate,
the rear sloped actuator comprising a rear height actuator and a rear width actuator;

wherein the intervertebral implant is configured to transition from a collapsed configuration having a first height and a
first width to an expanded configuration having a second height and a second width, non-symmetrically,

wherein the second height is greater than the first height and the second width is greater than the first width, and
wherein actuation of the front and rear width actuators transition the intervertebral implant from the first width to the
second width and actuation of the front and rear height actuators transition the intervertebral implant from the first height
to the second height such that the expansion of the implant from the first width to the second width is independent of the
expansion of the implant from the first height to the second height.

US Pat. No. 9,241,806

FLEXIBLE ANCHORING AND FUSION DEVICES AND METHODS OF USING THE SAME

Globus Medical, Inc., Au...

1. A medical device, comprising:
a spacer member configured to be implanted adjacent to an anatomical structure within a body of a patient, the spacer member
defining a curved bore, a first opening in a side wall of the spacer member and a second opening in at least one of a top
wall and a bottom wall of the spacer member, each of the first opening and the second opening being in fluid communication
with the curved bore, wherein the first opening is centrally and equidistantly positioned in between first and second lateral
sides of the spacer member, and wherein the curved bore has a first portion having a first width adjacent the first opening
and a second portion having a second width adjacent the second opening, wherein the first width is greater than the second
width, and wherein the curved bore of the spacer member includes a first threaded portion having inner threads formed within
at least a part of the first portion having the larger width, and the curved bore of the spacer member includes a second threaded
portion having inner threads formed within at least a part of the second portion; and

a flexible anchoring member configured to be inserted through the first opening and through the curved bore of the spacer
member such that a distal end portion of the flexible anchoring member extends out of the second opening at an angle relative
to the top wall or bottom wall of the spacer member, wherein in a first configuration, before the flexible anchoring member
is inserted through the curved bore, the flexible anchoring member has a substantially linear configuration, and in a second
configuration, after the flexible anchoring member is inserted through the curved bore, the flexible anchoring member is bent
to a curved configuration,

wherein the flexible anchoring member includes a threaded portion and is flexible along the entire threaded portion, the threaded
portion extending from a tip of the distal end of the flexible anchoring member to a head portion of the flexible anchoring
member, and the threaded portion of the flexible anchoring member is configured to threadably engage the inner threads of
the second threaded portion of the bore to secure the flexible anchoring member to the spacer wherein the spacer member is
inflatable.

US Pat. No. 9,278,216

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC., Au...

1. A spinal cord stimulation device comprising:
an implantable pulse generator;
a plurality of implantable stimulation electrodes;
a plurality of implantable leads electrically connecting the implantable pulse generator and the optional trial implantable
pulse generator to the plurality of stimulation electrodes;

an external charger having a primary charging coil;
a clinician programmer application provided on a computing device;
an optional patient programmer application provided on a mobile device; and
a communication device allowing communication between the computing device and the optional mobile device and the implantable
pulse generator and the optional trial implantable pulse generator
the implantable pulse generator comprising:
a casing having an epoxy header;
a lead contact assembly;
a circuit board comprising a plurality of output capacitors, an application specific integrated circuit and a microcontroller,
the microcontroller in communication with the communication device and with the application specific integrated circuit;

a rechargeable battery;
a feedthrough further comprising pins that connect to the circuit board;
a RF antenna; and
a secondary charging coil
wherein the application specific integrated circuit comprising a digital section and an analog section, wherein the digital
section comprises digital elements, timing generators, a plurality of comparators, arbitration control, pulse burst conditioner,
and electrode logic, and wherein the analog section comprises field effect transistors and a plurality of digital-to-analog
convertors,

wherein the arbitration control analyzes the timing generator envelope signals and permits only one signal to be active at
a time.

US Pat. No. 9,204,901

JOINTED ROD

Globus Medical, Inc., Au...

1. A spinal fixation device comprising:
a first spinal rod;
a second spinal rod;
a housing, wherein the housing includes an elongated opening;
a pivoting locking plug received in the housing, wherein the pivoting locking plug comprises an elongated cutout that is positioned
to correspond with the elongated opening of the housing, wherein the pivoting locking plug comprises a first end and a second
end and a body having an outer surface therebetween, and the elongated cutout extends from the first end; and

a set screw for compressing the outer surface of the pivoting locking plug between the first end and the second end,
wherein at least one of the first and second spinal rods is received within the elongated cutout of the pivoting locking plug,
wherein the first spinal rod is configured to move greater than 90° in a cephalad-caudal direction with respect to the second
spinal rod and the housing.

US Pat. No. 9,179,925

ANTERIOR PROSTHETIC SPINAL DISC REPLACEMENT

Globus Medical, Inc., Au...

14. An intervertebral prosthetic disc comprising:
a first endplate having a first surface configured to substantially engage with a first vertebral body and a second surface
comprising a contoured, partially spherical articulating surface;

a second endplate having a first surface configured to substantially engage with a second vertebral body and a second surface
comprising a contoured, partially cylindrical articulating surface, wherein the second endplate includes a sidewall having
a groove formed therein, wherein the groove has a first endpoint and a second endpoint;

a core element at least partially disposed between the first and second endplates, wherein the core element comprises a first
contoured surface in communication with and substantially corresponding to the curvature of the second surface of the first
endplate, and a second contoured surface substantially in communication with and substantially corresponding to the curvature
of the second surface of the second endplate, wherein at least a portion of the core is received within the groove of the
second endplate;

wherein the second surface of the core element comprises a first width, wherein the second surface of the second endplate
comprises a second width, the first width and second widths configured to permit rotation of the core element relative to
the second endplate in the coronal plane.

US Pat. No. 9,358,128

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. An intervertebral implant comprising:
a first endplate having an upper side and a lower side;
a second endplate having an upper side and a lower side;
a body portion having a first end, a second end, a first side portion connecting the first end and the second end, and a second
side portion connecting the first end and the second end; and

a translation member receivable in the body portion, the translation member including a first angled surface configured to
engage a surface of the first endplate and a second angled surface configured to engage a surface of the second endplate,

an actuation member having a first end and a second end and threaded portion extending along a portion between the first end
and the second end and a non-threaded portion extending between the first end and the second end,

wherein the threaded portion of the actuation member does not extend beyond the first angled surface of the translation member
and

wherein movement of the translation member causes the first angled surface to push against the surface of the first endplate
and the second angled surface to push against the surface of the second endplate, thereby causing outward expansion of the
first endplate and second endplate,

wherein the translation member further includes a third angled surface and a fourth angled surface, and wherein the third
angled surface is configured to push against the surface of the first endplate and the fourth angled surface is configured
to push against the surface of the second endplate

wherein the translation member is coupled to the first and second endplates, wherein movement of the translation member in
a first direction causes the first and second endplates to outwardly expand and movement of the translation member is in a
second direction causes the first and second endplates to contract towards one another

wherein a lip portion of the actuation member contacts a planar surface of the translation member and moves the translation
member when the actuation member is rotated.

US Pat. No. 9,283,001

SYSTEMS FOR SPINAL STABILIZATION

GLOBUS MEDICAL, INC., Au...

1. A method for spinal stabilization comprising:
providing a plurality of cross-links, each of the cross-links including a central rod holder and first and second extension
members extending therefrom;

operably attaching each of the cross-links to a vertebral body, whereby attachment comprises:
attaching the first extension member to a first fixation member, wherein the first fixation member is attached to the vertebral
body, wherein the first fixation member comprises a pair of upwardly extending arms for receiving a rod therein and a downwardly
extending mouth having a curved portion that transitions into a flat portion, wherein at least one of the upwardly extending
arms includes a first end and a second end, an outside surface that extends between the first end and the second end, an inside
surface configured to face the rod, an aperture extending from the outside surface to the inside surface, and a side-cut,
wherein the side-cut is formed on at least one of the first end and the second end and opens into a channel formed by the
pair of upwardly extending arms;

and attaching the second extension member to a second fixation member, wherein the second fixation member is attached to the
vertebral body; and

securing a rod member to the central rod holder of two or more cross-links, thereby creating a stabilized system across multiple
levels of the spine

wherein each one of the at least one of the upwardly extending arms include recessed portions that are configured to engage
with a insertion instrument

wherein the aperture of each of the upwardly extending arms are positioned in the recessed portions of the upwardly extending
arms.

US Pat. No. 9,517,090

POLYAXIAL CROSS CONNECTOR

Globus Medical, Inc., Au...

1. A coupling device comprising:
a connector member including an engagement portion configured and dimensioned to receive an elongate spinal fixation element;
a translation member having an end operatively associated with the connector member to provide polyaxial movement of the connector
member relative to the translation member, wherein a portion of the connector member extends through a bore formed in the
translation member; and

a locking member to secure the elongate spinal fixation element in the engagement portion of the connector member and to lock
the polyaxial movement, thereby fixing the connector member relative to the translation member, wherein the locking member
is received through the connector member and not the translation member.

US Pat. No. 9,439,682

POLYAXIAL SCREW

Globus Medical, Inc., Au...

1. A spinal implant comprising:
an elongated rod;
a bone fastener having a rounded head;
a coupling element comprising a coupling body and cap;
wherein the coupling body comprises sidewalls that define two upwardly extending arms which define two slots capable of receiving
the elongated rod;

wherein the coupling body and cap interact to capture the elongated rod in the coupling body,
wherein first and second protrusion configured on opposing sides of the cap and extend in a radial direction and first and
second recesses configured in the two upwardly extending arms extending in a radial direction and wherein the first and second
protrusions are configured and dimensioned to engage the first and second recess to limit movement of the cap with respect
to the coupling body, when the cap is rotated from a first position to a second position,

wherein the cap having a threaded opening for receiving a threaded locking element, the locking element capable of securely
holding the elongated rod in a fixed position relative to the coupling element,

wherein the cap further comprises a rim which extend radially outward from the top end of the perimeter of the cap,
wherein a first of the upwardly extending arms includes a third recess positioned between the first recess and the upper surface
of the first of the upwardly extending arms for receiving a first portion of the rim of the cap and a second of the upwardly
extending arms includes a fourth recess for receiving a second portion of the rim of the cap, the fourth recess positioned
between the second recess and the upper surface of the second of the upwardly extending arms, and

wherein the third recess extends along the length of an inner surface of the first of the upwardly extending arms and the
fourth recess extends along the length of an inner surface of the second of the upwardly extending arms.

US Pat. No. 9,198,697

SPINOUS PROCESS FIXATION SYSTEM AND METHODS THEREOF

GLOBUS MEDICAL, INC., Au...

1. An implantable device, comprising:
a barrel, the barrel having an upper portion and a lower portion;
an actuator assembly disposed in the barrel, the actuator assembly comprising a front ramped actuator in engagement with the
barrel, a rear ramped actuator in engagement with the barrel, and a central screw that extends from the rear ramped actuator
through the front ramped actuator;

a first plate having multiple projections extending from one side of the first plate, the first plate comprising a first portion
that extends from the upper portion and a second portion that extends form the lower portion;

a second plate having multiple projections extending from one side of the second plate, the second plate configured to be
received on the central screw, wherein the second plate comprises an upper portion, a lower portion, a central portion connecting
the upper portion and the lower portion, and a trunnion assembly disposed in an opening in the central portion, wherein the
trunnion assembly comprises a housing for receiving the central screw, a pair of chambers on either side of the opening, and
a pair of ratchet pawls, each of the ratchet pawls being individually disposed in one of the chambers and configured to engage
the central screw in the opening,

wherein the barrel is configured to transition from a collapsed form having a first height to an expanded form having a second
height and wherein the second height is greater than the first height.

US Pat. No. 9,364,340

LOW PROFILE PLATE

GLOBUS MEDICAL, INC., Au...

1. A spinal system comprising:
a spacer for inserting into an intervertebral space, the spacer including:
an upper surface,
a lower surface, and
an opening that extends between the upper surface to the lower surface;
a plate for abutting the spacer, the plate including:
a plate body,
a first opening formed in the plate body for receiving a first bone fastener, wherein the first opening is angled in an upward
direction;

a second opening formed in the plate body for receiving a second bone fastener, wherein the second opening is angled in a
downward direction;

a blocking mechanism for preventing back-out of both the first and the second bone fasteners, wherein the blocking mechanism
has a first position whereby the first and second bone fasteners can be inserted past the blocking mechanism and into the
first and second openings and a second position following rotation of the blocking mechanism whereby the first and second
bone fasteners are prevented from backing out by the blocking mechanism, and

a pair of extensions that extend from the plate body, wherein the extensions are configured to engage the spacer,
wherein each extension includes an enclosed window that extends along a length of the extension and wherein each of the windows
receives a portion that extends laterally outward from outer sidewalls of the spacer.

US Pat. No. 9,211,196

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. An intervertebral implant comprising:
a first endplate having an upper side and a lower side, wherein the lower side of the first endplate includes a plurality
of ramped surfaces extending therefrom;

a second endplate having an upper side and a lower side;
a body portion having a first end, a second end, a first side portion connecting the first end and the second end, and a second
side portion connecting the first end and the second end, wherein the first end plate and the second endplate are received
within the body;

a translation member receivable in the body portion, the translation member including a first expansion portion having an
angled surface configured to engage one ramped surface extending from the first endplate and a second expansion portion having
an angled surface configured to engage another of the ramped surfaces extending from the first endplate; and an actuation
member comprising a threaded member, wherein the actuation member is non-threadably engaged with the translation member, wherein
rotation of the actuation member causes translational movement of the translation member, and

wherein movement of the translation member causes the first expansion portion and second expansion portion to move from the
first end of the body portion to the second end of the body portion causing the angled surface of the first expansion portion
to push against one ramped surface extending from the first endplate and the angled surface of the second expansion portion
to push against another ramped surface extending from the first endplate, thereby causing outward expansion of the first endplate.

US Pat. No. 9,179,944

SPINOUS PROCESS FUSION DEVICES

GLOBUS MEDICAL, INC., Au...

1. An implantable device comprising:
a body;
a first wing coupled to the body; and
a second wing having a through hole;
wherein a portion of the body extends through the through hole of the second wing;
wherein a ratcheting lock secures the second wing on the body,
wherein the body is adapted to be positioned between spinous processes of adjacent vertebra and is configured for distraction
of interspinous space,

wherein the first and second wings comprise teeth for engaging with the adjacent spinous processes, wherein the first wing
includes one or more teeth in an upper portion of the first wing above the body and one or more teeth in a lower portion of
the first wing below the body,

wherein the second wing translates from a first position to a second position along the body and is freely rotatable about
a longitudinal axis of the body in the first position and not freely rotatable in the second position

wherein a portion of an outer surface of the body is positioned within the through hole of the second wing
wherein the body comprises a rod disposed through the through hole in the second wing
wherein the rod is configured to spread to increase a diameter of the rod.

US Pat. No. 9,119,730

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. An intervertebral implant comprising:
a first endplate having an upper side and a lower side;
a second endplate having an upper side and a lower side, wherein at least one of the first endplate and the second endplate
includes a pair of ramps extending from a surface thereof,

wherein the pair of ramps comprises a first ramp and a second ramp extending along a longitudinal length of at least one of
the first endplate and the second endplate, wherein the first ramp is positioned closer to a proximal end of at least one
of the first endplate and the second endplate than the second ramp, and the second ramp is positioned closer to a distal end
of at least one of the first endplate and the second endplate than the first ramp;

a body portion having a first end, a second end, a first side portion connecting the first end and the second end, and a second
side portion connecting the first end and the second end;

a translation member having a first end and a second end configured to push directly in contact against the pair of ramps,
thereby causing expansion of the first endplate relative to the second endplate, wherein the translation member comprises
a first angled surface and a second angled surface separated by a bridge portion, the first angled surface and the second
angled surface each being in contact with the first and second ramps respectively, wherein the first angled surface is positioned
closer to a proximal end of the translation member than the second angled surface, and the second angled surface is positioned
closer to a distal end of the translation member than the first angled surface;

an actuation member engageable with the translation member, wherein rotation of the actuation member causes translational
movement of the translation member

wherein the actuation member comprises a first end and a second end and threading extending along at least a portion of the
actuation member from the first end to the second end,

wherein the first angled surface is a portion of a first expansion portion and the second angled surface is a portion of a
second expansion portion, the first expansion portion including a opening for receiving the actuation member, the actuation
member configured to not extend beyond the second expansion portion,

wherein the actuation member is threadedly retained in the body and
wherein when the actuation member is rotated, the first and second expansion portions move in the same direction from a first
end of the first and second endplates towards a second end of the first and second endplates causing the first and second
endplates to move.

US Pat. No. 9,084,640

INTERSPINOUS INTERNAL FIXATION/DISTRACTION DEVICE

GLOBUS MEDICAL INC., Aud...

1. A surgical method comprising:
exposing a pair of spinous processes having an interspinous space therebetween;
inserting a device into the interspinous space, wherein the device comprises a proximal wing and a distal wing operably coupled
by an elongated shaft; and

rotating the device within the interspinous space such that the proximal wing is along one side of the pair of spinous processes
and the distal wing is along the opposite side of the pair of spinous processes

wherein the elongated shaft comprises a central core member extending between the proximal wing and the distal wing, the central
core member comprising a bore for receiving a bolt therethrough;

wherein the proximal wing is fixed to one end of the bolt;
wherein the bolt is configured to extend through the bore of the central core member and through the distal wing;
wherein a nut is positioned on the bolt after passing the bolt through the distal wing to secure the distal wing to the central
core member;

wherein the distal wing is rotatable with respect to the bolt; and
wherein a pilot hole is configured in a central shaft of the bolt and wherein the pilot hole extends throughout the bolt and
the nut for receiving a lever device for rotating the wings from a first position to a second position.

US Pat. No. 9,308,369

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC., Au...

1. An implantable pulse generator comprising:
a casing having an epoxy header;
a circuit board housed in the casing comprising:
a microcontroller;
a single application specific integrated circuit (ASIC) in communication with the microcontroller, the single ASIC having
a combined analog and digital sections, wherein the analog section further comprises at least one pair of digital to analog
convertors (DAC) wherein one of the pair is a positive current DAC and the other of the pair is a negative current DAC, and
wherein the ASIC generates stimulation signals;

a plurality of output capacitors;
a power management chip in electrical communication with the microcontroller; and
support circuitry;
an implantable grade lithium ion rechargeable battery housed in the casing and in electrical communication with the circuit
board;

a charging coil in electrical communication with the rechargeable battery;
a RF antenna housed in the epoxy header; and
a wireless interface.

US Pat. No. 9,204,900

INTERSPINOUS LIGAMENT TRANSVERSE CONNECTOR

GLOBUS MEDICAL, INC., Au...

12. A system for stabilizing the spine comprising:
a first and second elongate rod;
a third elongate rod connecting the first and second elongated rod in a cross connection assembly comprising:
a one-piece connecting body comprising a first elongated portion having first and second ends, a second elongated portion
having first and second ends, the second end of the first elongated portion and the first end of the second elongated portion
are integrally formed with each other to form an L-shaped body, wherein the first end of the first elongated portion comprises
a receptacle facing outwards towards the first rod and away from the second rod, and the second end of the second elongated
portion comprises a clamp, the clamp comprising an upper clamp portion and a lower clamp portion and an opening therebetween;
and

a set screw selectively positioned to securely hold the connecting body to the first rod;
wherein the connecting body is disposed substantially between the first and second elongate rods;
wherein the clamp allows the connecting body to slidingly engage with the third rod;
wherein a fastener causes the clamp to be clamped around the third rod, thereby locking the third rod relative to the connecting
body, wherein the fastener is located at the second end of the second elongated potion and the set screw is located at the
first end of the first elongated portion such that from a top view of the one-piece body, the set screw is offset both vertically
and horizontally from the fastener;

wherein the third rod is configured and designed with frusto-conical tips.

US Pat. No. 9,724,204

METHOD FOR INSERTING AND POSITIONING AN ARTIFICIAL DISC

Globus Medical, Inc., Au...

1. An intervertebral prosthetic disc comprising:
a first endplate having a plurality of protrusions for attaching to a first adjacent vertebrae and an extension portion extending
towards a second adjacent vertebrae, the extension portion being spaced apart from a base of the first endplate when assembled;

a second endplate having a plurality of protrusions for attaching to the second adjacent vertebrae and an extension portion
extending towards the first adjacent vertebrae, the extension portion being spaced apart from a base of the second endplate
when assembled;

a resilient member having an upper portion and a lower portion;
a slider plate having an upper and lower surface positioned and enclosed within a first cavity in the upper portion of the
resilient member, wherein the upper surface of the slider plate is configured to contact a lower surface of the extension
portion of the first endplate; and,

wherein the extension portion of the first endplate is adapted to fit within the first cavity in the upper portion of the
resilient member and the extension portion of the second endplate is adapted to fit within a second cavity in the lower portion
of the resilient member,

wherein the extension portion of the first endplate engages with the upper surface of the slider plate to allow translation
or rotation of the extension portion relative to the slider plate,

wherein a length of extension portion of the first endplate is smaller than a length of the slider plate.
US Pat. No. 9,486,483

BONE GRAFTS INCLUDING OSTEOGENIC STEM CELLS, AND METHODS RELATING TO THE SAME

Globus Medical, Inc., Au...

1. A bone graft having viable cells, the bone graft comprising:
a mixture of non-demineralized cortico-cancellous chips and demineralized cortical bone which form a scaffold without an additional
natural or synthetic material, the cortico-cancellous chips obtained from condyles and the demineralized cortical bone obtained
from cortical shafts of long bones; and

osteogenic stem cells seeded on the scaffold to form the bone graft having viable cells capable of bone regeneration, wherein
the osteogenic stem cells are obtained from cells cultured from a mixture of bone marrow and cells from cancellous bone treated
with collagenase.

US Pat. No. 9,414,874

LOW PROFILE FASTENING ASSEMBLY

GLOBUS MEDICAL, INC., Au...

1. A surgical method comprising: inserting a bone plate into a patient, wherein the bone plate comprises an opening extending
from an upper surface of the bone plate to a lower surface of the bone plate, wherein the bone plate comprises one or more
grooves in communication with the opening; inserting a fastener assembly into the bone plate, wherein the fastener assembly
comprises a locking head comprising an extension; and rotating the fastener assembly such that the extension is received in
the one or more grooves of the bone plate to thereby prevent backout of the fastener assembly from the bone plate, wherein
the locking head extending from most upper surface of the bone plate to most lower surface of the bone plate, and wherein
the fastener assembly comprises a fastener including a head portion, a neck portion and a shank portion, wherein the head
portion is received in an opening formed in the locking head.

US Pat. No. 9,119,675

TRANSVERSE FIXATION DEVICE FOR SPINAL FIXATION SYSTEMS

GLOBUS MEDICAL, INC., Au...

1. An implantable system comprising:
a first connecting body having a one-piece body comprising a first collar and a first receptacle;
a second connecting body comprising a second collar and a second receptacle;
a first elongate body received in the first receptacle;
a second elongate body received in the second receptacle, wherein the first receptacle faces outwards towards the first elongate
body and away from the second elongate body;

a third elongate body received in the first collar and the second collar, wherein the third elongate body is laterally offset
from the first receptacle of the first connecting body for accommodating anatomical structural elements, and

a first c-ring received in the first collar, wherein the first c-ring receives the third elongate body, and wherein a screw
tightens the first collar around the first c-ring and the third elongate body,

wherein the first connecting body and the second connecting body are each capable of translating axially along the third elongate
body, and

wherein locking of the first elongate body in the first receptacle is independent from locking of the third elongate body
in the first collar of the first connecting body.

US Pat. No. 9,089,371

ORTHOPEDIC STABILIZATION DEVICES AND METHODS FOR INSTALLATION THEREOF

Globus Medical Inc., Aud...

13. A spinal stabilization system comprising:
a fastener member comprising a head, a threaded body extending longitudinally from the head, and a socket;
a torsion member comprising:
a distal section configured to be received within the socket,
a flexible body, and
a proximal section comprising an externally-threaded portion and a tool-receiving recess;
a relief member comprising a bore extending longitudinally therethrough, a body comprising external threading, and a proximal
end having a tool-receiving recess, wherein the bore comprises an internally-threaded portion configured to mate with the
externally-threaded portion of the torsion member; and

a compression member comprising a proximal end having a tool-receiving recess and a bore extending longitudinally therethrough,
wherein the bore comprises an internally-threaded portion configured to mate with the external threading of the relief member.

US Pat. No. 9,566,168

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. An intervertebral implant comprising:
an upper endplate comprising upper endplate pins, a first upper endplate portion and a second upper endplate portion;
a lower endplate comprising lower endplate pins, a first lower endplate portion and a second lower endplate portion;
an actuator assembly disposed between the upper endplate and the lower endplate, the actuator assembly being configured to
movingly engage front ends of the upper endplate and the lower endplate and also movingly engage rear ends of the upper endplate
and the lower endplate;

wherein the actuator assembly is configured to move the upper endplate and lower endplate relative to each other from a collapsed
configuration having a first width and a first height to a laterally expanded configuration having a second width and a vertically
expanded configuration having a second height,

wherein the actuator assembly comprises a front sloped actuator, a rear sloped actuator and a linear actuator, wherein the
linear actuator is configured to move the front sloped actuator and the rear sloped actuator together or away from each other
to move the upper and lower endplates,

wherein the upper and lower endplates comprise a front ramped surface and a rear ramped surface, the front and rear ramped
surfaces of the upper and lower endplates configured to be coupled to the front sloped actuator and the rear sloped actuator,
respectively,

wherein the upper endplate includes slots for receiving the upper endplate pins,
wherein the lower endplate includes slots for receiving the lower endplate pins,
wherein the endplate pins extend transversely to the linear actuator.

US Pat. No. 9,492,283

EXPANDABLE SPACER AND METHOD OF USE THEREOF

GLOBUS MEDICAL, INC., Au...

1. A method for facilitating fusion of two adjacent joint surfaces in a patient comprising the steps of:
accessing a site in the patient's body having two adjacent joint surfaces to be fused;
providing an expandable implant having a first, collapsed height;
preparing a space between the two adjacent joint surfaces for insertion of the implant;
inserting the implant into the prepared space;
wherein the expandable implant comprises:
a first and a second threaded shaft;
a first gear and a second gear;
a base plate, the first and second gears are rotatably and non-translatable coupled to the base plate; and
the first and second gears operably coupled with the first and second threaded shafts, said first and second gear having interior
surfaces including threads matably engaged with said first and second threaded shafts, whereby rotation of said first and
second gears initiates displacement of said first and second threaded shafts, whereby said first and second threaded shafts
are extendable in a direction away from said base plate;

wherein the first and second shafts are coupled to a top plate,
wherein the first and second gears are positioned substantially perpendicular to the base plate and adjacent to one another,
wherein the first and second gears engage with each other,
expanding the expandable implant; and
closing the site in the patient's body.

US Pat. No. 9,364,272

BONE FIXATION PLATE

GLOBUS MEDICAL, INC., Au...

1. A fastener system for mounting an implant to bone comprising:
an elongate fastener having a longitudinal axis, a proximal end, and a distal end;
a shaft portion including a threaded portion disposed on the distal end of the fastener, wherein said threaded portion is
capable of screwing into bone;

a fastener head disposed on the proximal end of the fastener, wherein the fastener head comprises:
a partially spherical outer surface;
an interior surface defining a receptacle for receiving a locking fastener, wherein the interior surface is non-threaded;
and

at least one slit extending between the outer surface and interior surface of the fastener head to permit outward expansion
of the fastener head, the at least one slit extending exclusively along a length of the fastener head without entering the
shaft portion;

a locking fastener capable of being received in the receptacle of the fastener head,
wherein the locking fastener has a different configuration than the receptacle to create and apply a locking force; and
a plate having at least one aperture including an interference area integrally formed therein configured to prevent the elongate
fastener from backing out of the interference area,

wherein the at least one aperture has a spherical curvature extending at least partially through the thickness of the plate,
wherein insertion of the fastener head interferes with the interference area, and wherein the fastener head is capable of
engaging with and passing the interference area to communicate with the spherical curvature.

US Pat. No. 9,314,273

PERCUTANEOUS VERTEBRAL STABILIZATION SYSTEM

Globus Medical, Inc., Au...

1. A method for inserting a vertebral stabilization member percutaneously, comprising:
providing a stabilization member extending from a proximal end to a distal end along a first longitudinal axis;
providing a stabilization member insertion device releasably linked to the stabilization member;
providing a first sleeve and a second sleeve attachable to a first bone anchor and a second bone anchor,
attaching the stabilization member to the stabilization member insertion device;
inserting the stabilization member insertion device percutaneously into a patient; and
using the stabilization member insertion device positioning the stabilization member between the first and second bone anchor,
wherein the insertion device extends from a proximal end to a distal end along a second longitudinal axis, the insertion device
comprising a first member and a second member,

wherein the first member is linearly translatable with respect to the second member along the second longitudinal axis,
wherein the stabilization member is linkingly engaged to the first member at a first axial location along the stabilization
member and rotatably engaged to the second member at a second axial location along the stabilization member that is axially
offset from the first axial location such that, when the first member is translated with respect to the second member along
the second longitudinal axis the stabilization member rotates about the second member; and

wherein the stabilization member is actuatable by the insertion device from a first orientation substantially parallel to
the second longitudinal axis to a second orientation substantially perpendicular to the second longitudinal axis

wherein at least one of the first and second sleeves includes one or more resilient tabs integral with a sidewall of at least
one of the first and second sleeves, wherein one or more of the resilient tabs includes a ramp portion and lip portion.

US Pat. No. 9,233,009

EXPANDABLE INTERVERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. An expandable implant comprising:
an upper endplate;
a lower endplate, wherein at least one of the upper endplate and the lower endplate include a bore hole for receiving a bone
fastener therethrough;

an actuator positioned between the upper endplate and the lower endplate; and
an actuator screw for actuating the actuator, wherein rotation of the actuator screw causes movement of the actuator, thereby
causing expansion or contraction of the implant

wherein the actuator includes a frame rotatably supporting the actuator screw and a translation member,
wherein as the actuator screw rotates within the frame, the translation member moves within the frame from a first position
to a second position by cooperation between threads upon the actuator screw and mating threads of the translation member,

wherein the translation member is supported within the frame by at least two support screws engaged with the translation member
and passable through respective channels formed in the frame,

wherein the actuation screw extends from a proximal end of the translation member through a distal end of the translation
member and contacts an inner surface of the frame.

US Pat. No. 9,211,142

FLEXIBLE ELEMENT FOR SPINE STABILIZATION SYSTEM

Globus Medical, Inc., Au...

1. A flexible connection element for connecting a first vertebra with respect to a second vertebra, comprising:
an elongate body extending from a first end portion to a second end portion along a longitudinal axis, the first and second
end portions connected by and fixed to a cord member, the cord member made from a nonmetal material,

the elongate body comprising first and second attachment portions disposed coaxial with the cord member, the attachment portions
made from a rigid material and configured and dimensioned to attach to bone fasteners to connect the elongate body between
first and second vertebrae,

the elongate body further comprising first and second resilient members disposed coaxial with the cord member, the first resilient
member positioned between the first end portion and the first attachment portion, and the second resilient member positioned
between the first attachment portion and the second attachment portion,

wherein the first and second attachment portions compress the second resilient member therebetween when the first and second
attachment portions move towards each other, and

wherein the first end and first attachment portions compress the first resilient member therebetween when the first and second
attachment portions move away from each other; and

wherein the first and second end portions define an annular cannula for receiving at least a portion of the cord member therein,
wherein at least one of the first and second attachment portions comprises an upper clamp body and a lower clamp body, wherein
the upper clamp body has a pair of arms and a piercing element positioned between the pair of arms, wherein each of the pair
of arms is configured with a first and second opening for receiving first and second protrusion from the lower clamp body,
wherein each of the arms of the upper clamp body overlie an outer surface of the lower clamp body.

US Pat. No. 9,119,679

ANGLED WASHER POLYAXIAL CONNECTION FOR DYNAMIC SPINE PROSTHESIS

GLOBUS MEDICAL, INC., Au...

1. A method for stabilizing a spine comprising the steps of:
accessing posterior portions of the spine;
providing a dynamic spine prosthesis comprising:
a fixation element having an elongated bone entry portion defining a longitudinal axis;
a dynamic spine prosthesis component connected to the fixation element at a connection location by an adjustable connection,
the adjustable connection comprising first and second washers each rotatably supported by the fixation element and each having
an angled contact surface in a plane not perpendicular to the longitudinal axis of the fixation element, the connection location
being between the bone entry portion and the first and second washers, wherein the angled contact surfaces of the first and
second washers are in contact with each other; and

a third washer between the dynamic spine prosthesis and the bone entry portion of the fixation element, and
positioning the dynamic spine prosthesis on the spine.

US Pat. No. 9,101,768

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC., Au...

1. An implantable pulse generator comprising:
a casing having an epoxy header;
a circuit board housed in the casing comprising:
a microcontroller;
a single application specific integrated circuit (ASIC) in communication with the microcontroller, the single ASIC having
a combined analog and digital sections, wherein the analog section further comprises at least one pair of digital to analog
converters (DAC) wherein one of the pair is a positive current DAC and the other of the pair is a negative current DAC, and
wherein the ASIC generates stimulation signals;

a plurality of output capacitors;
a power management chip in electrical communication with the microcontroller; and
support circuitry;
an implantable grade lithium ion rechargeable battery housed in the casing and in electrical communication with the circuit
board;

a charging coil in electrical communication with the rechargeable battery;
a RF antenna housed in the epoxy header;
a lead contact system housed in the epoxy header wherein the lead contact system provides connection for up to thirty-two
leads;

a feedthrough having a plurality of pins that interface on one side with the circuit board and interface on the other side
with the lead contact system and the RF antenna;

a wireless interface
wherein the wireless interface is configured to operate in the 402 MHz to 405 MHz range utilizing up to 10 channels for telemetry
enabling interoperability.

US Pat. No. 9,510,957

INSERTION TOOL ASSEMBLY

Globus Medical, Inc., Au...

1. A surgical system comprising:
an insertion tool assembly for delivering an implant to a surgical site, wherein the insertion tool assembly comprises:
a handle assembly;
a sleeve assembly extending from the handle assembly; and
a gripping tip operably connected to the sleeve assembly, wherein the gripping tip comprises a proximal portion, a body and
a distal portion, wherein the distal portion comprises a first jaw portion and a second jaw portion; and

an implant for delivery to the surgical site, wherein the implant comprises a spacer having a body formed of a top surface,
a bottom surface and an opening that extends through the top surface and the bottom surface, wherein a first portion of the
spacer is received within the first recess in the first jaw portion and a second portion of the spacer is received within
the second recess in the second jaw portion when the spacer is attached to the insertion tool assembly

wherein the gripping tip further includes a first drill guide and a second drill guide, wherein the first drill guide is angled
upwardly while the second drill guide is angled downwardly.

US Pat. No. 9,498,257

CONNECTION ASSEMBLY

Globus Medical, Inc., Au...

1. A method for stabilizing a spine comprising the steps of:
providing an orthopedic connection assembly comprising:
a housing member including a first aperture for receiving a securing member and a second aperture for receiving a spinal implant;
a plate member insertable into the housing member through a third aperture;
an interference member capable of engagement by the plate member;
a receiving member for receiving the interference member therein, the receiving member including a receiving aperture for
receiving an anchor member therethrough; and

a cap member receivable over the receiving member and mateable with the housing member,
wherein the assembly is configured to allow for a number of variable angles between the spinal implant and the anchor member;
implanting the anchor member into a vertebral body of the spine;
securing the spinal implant at one of the variable angles relative to the anchor member.

US Pat. No. 9,456,903

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

Globus Medical Inc., Aud...

1. An intervertebral implant comprising:
a body portion having a central opening;
a first endplate comprising an upper side, a lower side, a first ramped portion and a second ramped portion, the first and
second ramped portions extending from the lower side into the central opening;

a second endplate comprising an upper side, a lower side, a third ramped portion, and a fourth ramped portion, the third and
fourth ramped portions extending from the lower side into the central opening; and

a translation member received within the central opening, the translation member comprising a first angled surface, a second
angled surface, the first angled surface engages the first ramped portion, and the second angled surface engages the second
ramped portion;

wherein movement of the translation member in a first direction causes the first and second endplates to move in a direction
away from the body portion and the movement of the translation member in a second direction causes the first and second endplates
to move in a direction towards the body portion, and

wherein the first and second angled surface are at a first distance from each other when the first endplate is in an unexpanded
position and at a second distance at an expanded position, wherein the first and second distances are equal.

US Pat. No. 9,421,037

DISPENSING FASTENERS

GLOBUS MEDICAL, INC., Au...

1. A device for dispensing a series of fasteners to be implanted within a patient, the device comprising:
a magazine defining a longitudinal axis and having a distal opening, said magazine sized and dimensioned to hold the series
of fasteners, the series of fasteners insertable through said distal opening, said magazine comprising a proximal end and
a distal end;

a support having a splined guide bore aligned with said longitudinal axis of said magazine, said support connected to said
magazine to be rotatable radially with respect to said longitudinal axis;

a shaft slideably disposed within said support;
a biasing element connected between said support and said shaft, said biasing element configured to urge said shaft along
said longitudinal axis in a direction towards said distal end relative to a location of said support; and

a ratchet connected to said shaft and engageable with said magazine to permit sliding of said shaft in a first direction towards
said distal end, to prevent sliding of said shaft in a second direction away from said distal end in a first position, and
to enable sliding of said shaft in said second direction in a second position, said ratchet movable from said first position
to said second position when said support is rotated radially with respect to said longitudinal axis, said ratchet including
one or more ratchet pawls, said ratchet pawls engageable with said magazine, said ratchet pawls movable in a direction transverse
to said longitudinal axis;

wherein once a first of the series of fasteners is dispensed, the biasing element urges the shaft towards the proximal end
to thereby position a second of the series of fasteners for dispensing,

wherein the biasing element is a spring,
wherein one or more projections extend inwardly at the distal end of the magazine, wherein the one or more projections are
sized and shaped to engage one or more tool flanges of each of the fasteners such that tilting of the device causes portions
of the one or more tool flanges to pass the one or more projections thereby allowing for dispensation of the fasteners.

US Pat. No. 9,402,738

DEVICES AND METHODS FOR CORRECTING VERTEBRAL MISALIGNMENT

Globus Medical, Inc., Au...

11. A vertebral implant, comprising:
a frame assembly including a left lateral portion, a central portion, and a right lateral portion, wherein the left and right
lateral portions define enlarged heads configured to receive fasteners therein for securing the frame assembly to a first
vertebral body, and wherein the central portion includes a longitudinal member extending from a posterior end to an anterior
end of the frame, the longitudinal member having a lumen therethrough;

a reducing member configured to be slidably received over the longitudinal member, wherein the reducing member includes an
anterior portion and a plurality of extensions extending posteriorly therefrom, wherein the plurality of extensions define
a channel therebetween, wherein the channel is configured to receive a portion of the frame;

an actuator configured to extend from an anterior surface of the reducing member into the lumen of the longitudinal member
of the frame assembly, the actuator configured to control a position of the reducing member relative to the frame assembly;
and

a plurality of fastener restricting mechanisms for retaining the fasteners within the enlarged heads.

US Pat. No. 9,393,052

MINIMALLY INVASIVE SPINE RESTORATION SYSTEMS, DEVICES, METHODS AND KITS

GLOBUS MEDICAL, INC, Aud...

1. A surgical system comprising:
first and second upper anchors, wherein the first upper anchor supports a first upper bearing surface and the second upper
anchor supports a second upper bearing surface, wherein the first upper anchor is operably connected to a first housing, wherein
the second upper anchor is connected to a second housing, and wherein a first crossbar is downwardly deposited such that a
first portion of the first crossbar is received in a first anchor body of the first housing and a second portion of the first
crossbar is received in a second anchor body of the second housing; and

first and second lower anchors, wherein the first lower anchor supports a first lower bearing surface and the second lower
anchor supports a second lower bearing surface, wherein the first upper bearing surface is positioned directly against the
first lower bearing surface and the second upper bearing surface is positioned directly against the second lower bearing surface;
and

wherein the first and second lower bearing surfaces are modular such that they are capable of removable attachment from the
system

wherein a first fastener is positioned to fit into an opening of the first anchor body thereby bearing down and locking the
first portion of the first crossbar to the anchor body and a second fastener is positioned to fit into an opening of the second
anchor body to thereby bearing down and locking the second portion of the first crossbar to the second anchor body,

wherein the first and second lower bearing surfaces are attached to the first and second lower anchors via dovetail surfaces.

US Pat. No. 9,320,556

BIOMATERIAL DISPENSING DEVICE

GLOBUS MEDICAL, INC., Au...

1. A device for dispensing biomaterial, the device comprising:
a handle configured to receive a syringe, the syringe comprising a plunger;
an engagement pin retained within the handle and moveable between a first position and a second position, the engagement pin
configured to engage the plunger in the first position, wherein the engagement pin further is configured to disengage from
the plunger in the second position;

a lid pin located in a side of the lid and configured to fit into a corresponding hole in the handle; and
a lid spring configured to press the lid in a direction substantially parallel to the lid pin axis, the spring further configured
to retain the lid pin in its corresponding hole until released by a user of the device.

US Pat. No. 9,295,509

METHODS AND APPARATUS FOR TREATING VERTEBRAL FRACTURES

GLOBUS MEDICAL, INC., Au...

1. A method for treating a bone comprising:
creating a cavity in the bone, wherein the cavity has a proximal end and a distal end;
inserting a containment jacket into the cavity through the proximal end of the cavity;
inserting a balloon into the containment jacket, wherein the balloon has a proximal end closer to the proximal end of the
cavity and a distal end closer to the distal end of the cavity, wherein an enclosure is disposed over the balloon, the enclosure
having a proximal end closer to the proximal end of the balloon and a distal end closer to the distal end of the balloon,
wherein the distal end of the balloon extends past the distal end of the enclosure;

inflating the balloon, wherein the enclosure remains generally unstressed and completely intact when the balloon is in a fully
inflated working state; and

introducing a filler material into the containment jacket while the balloon remains inflated within the containment jacket,
wherein the filler material is introduced into a space in the containment jacket that is more distal than a distal most end
of the balloon; and

permanently positioning the containment jacket in the bone,
wherein the containment jacket allows for interdigitation of the filler material with cancellous bone.

US Pat. No. 9,179,937

POLYAXIAL SCREW

Globus Medical, Inc., Au...

1. A spinal implant comprising:
a screw member, the screw member comprising a head member and a shaft, wherein at least a portion of the shaft is threaded,
and wherein at least a portion of the shaft is tapered;

an elongate rod member;
a cylindrical coupling body including a longitudinal axis, wherein the cylindrical coupling body is configured to receive
the screw member and the elongate rod member, the coupling body comprising a U-shaped member formed by a first upwardly extending
arm and a second upwardly extending arm, wherein the first upwardly extending arm includes a first inner wall and a first
outer wall and the second upwardly extending arm includes a second inner wall and a second outer wall, wherein the first inner
wall of the first extending arm includes a first channel and a first groove disposed above the first channel, wherein the
second inner wall of the second extending arm includes a second channel and a second groove disposed above the second channel;
and

a non-threaded locking cap insertable into the coupling body over the screw member and the elongate rod member, the non-threaded
locking cap comprising a first protrusion and a second protrusion, the non-threaded locking cap further comprising a first
upper rim portion disposed above the first protrusion and a second upper rim portion disposed above the second protrusion,

wherein upon rotation of the locking cap within the coupling body, the first protrusion is configured to be received in the
first channel and the second protrusion is configured to be received in the second channel, and the first rim portion is configured
to be received in the first groove and the second rim portion is configured to be received in the second groove,

wherein a width of the first upwardly extending arm and a width of the second upwardly extending arm varies along the longitudinal
axis of the cylindrical coupling body such that a greatest diameter between the first outer wall and the second outer wall
along the longitudinal length of the cylindrical coupling body is found adjacent the first channel and the second channel.

US Pat. No. 9,808,349

EXPANDABLE VERTEBRAL IMPLANT

Globus Medical Inc, Audu...

1. An expandable prosthetic implant for engagement between vertebrae, comprising:
an inner member having a hollow interior portion and an external portion and including a first end portion, the inner member
being centered along a first longitudinal axis, the first end portion comprising a first screw hole and a second screw hole;

a first screw configured and dimensioned to be received in the first screw hole and a second screw configured and dimensioned
to be received in the second screw hole, the first and second screws capable of engaging a first vertebral body;

a first blocking member having a second longitudinal axis positioned transverse to the first longitudinal axis, the first
blocking member being rotatable about the second longitudinal axis from a first position to a second position,

an outer member having a hollow interior portion configured to coaxially receive the inner member therein and including a
second end portion, the second end portion comprising a third screw hole and a fourth screw hole;

a third screw configured and dimensioned to be received in the third screw hole and a fourth screw configured and dimensioned
to be received in the fourth screw hole, the third and fourth screws capable of engaging a second vertebral body;

a gear member positioned coaxial to the inner member and outer member and axially fixed to the outer member, the gear member
includes a helical thread along at least part of an inner wall and an array of gear teeth along a portion of an exterior wall,
the gear teeth extending from a proximal end of the gear member to a distal end of the gear member; and

a locking member configured to restrict relative movement between the inner member and the outer member, wherein the locking
member is configured to be received in the outer member, wherein the locking member includes an engagement member that engages
the gear member to prevent rotation of the gear member, and wherein said engagement member is an upwardly protruding engagement
member configured to be received in a cutout in the gear member;

wherein the inner and outer members are moveable relative to each other along the first longitudinal axis,
wherein the locking member includes a through hole for receiving a tool to move the locking member relative to the gear member
in a direction parallel to the first longitudinal axis.

US Pat. No. 9,603,645

CEMENT-DIRECTING ORTHOPEDIC IMPLANTS

Globus Medical, Inc., Au...

1. A device for use in treating orthopedic defects in a procedure comprising inserting the device into a pre-formed cavity
within a bony member and injecting bone cement or other orthopedic filler material into an interior region of the device,
said device comprising: a collapsible, self-expanding mesh structure configured to have a first, collapsed configuration and
a second, expanded configuration, wherein said mesh structure is a co-braided structure and has regions of different permeability
or flow resistance, wherein said mesh structure comprises primary members and secondary members occupying interstices between
said primary members, and wherein said mesh structure includes a coating on at least a portion of the mesh structure configured
to control the direction of the bone cement or other orthopedic filler material through the mesh structure.

US Pat. No. 9,561,054

ORTHOPEDIC FIXATION DEVICES AND METHODS OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. An assembly comprising:
a male hook component configured to be inserted onto a bone member, wherein the male hook component comprises a rod member;
a female hook component operably connected to the male hook component, the female hook component slidably engages the rod
member of the male hook component, wherein the female hook component comprises a head member, wherein the female hook component
is configured to be tightened onto the male hook component to secure the female hook component to the male hook component;
and

a modular tulip assembly configured to be positioned on top of the head member of the female hook component.

US Pat. No. 9,486,325

EXPANDABLE INTERVERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. An implant comprising:
a frame;
an actuator;
an upper endplate positioned above the frame, wherein the upper endplate includes at least one upper socket for receiving
a bone screw therethrough; and

a lower endplate positioned below the frame, wherein the lower endplate includes at least one lower socket for receiving a
bone screw therethrough,

wherein a blocking element is associated with each socket for preventing the respective bone screws from backing out,
wherein rotation of the actuator causes the implant to move from an unexpanded configuration to an expanded configuration,
wherein in the unexpanded configuration the upper endplate including the at least one upper socket is positioned a first distance
away from the lower endplate including the at least one lower socket, wherein in the expanded configuration the upper endplate
including the at least one upper socket is positioned a second distance away from the lower endplate including the at least
one lower socket, wherein the second distance is greater than the first distance.

US Pat. No. 9,358,127

INTERVERTEBRAL FUSION IMPLANT

Globus Medical, Inc., Au...

1. An intervertebral implant for implantation in a treated area of an intervertebral space between vertebral bodies of a spine,
wherein said implant comprises:
a spacer portion having an inferior and a superior surface, an anterior surface, posterior surface, and first and second sides,
wherein the inferior and superior surfaces each have a contact area capable of engaging with anatomy in the treated area,
and the inferior and superior surfaces define a through-hole extending through the spacer portion;

at least a first hole extending from the anterior surface to the superior surface of the spacer portion and at least a second
hole extending from the anterior surface to the inferior surface of the spacer portion;

a plate portion rigidly coupled to the spacer portion through a coupling mechanism, wherein the plate portion contains at
least first and second holes extending from an anterior surface of the plate to a posterior surface of the plate, the at least
first and second holes configured for receiving fasteners; and

wherein a fastener back out prevention mechanism is adapted on the plate portion and prevents the back out of the fasteners
from the first and second holes,

wherein the spacer portion length from the anterior surface to the posterior surface is greater than a distance from a first
side to a second side of the plate portion,

wherein a width of the spacer portion from the first side to the second side is greater than the width of the plate portion,
wherein the spacer portion and the plate portion are configured to be positioned laterally
wherein the through-hole extending through the spacer portion from the inferior surface to the superior surface is configured
with a length extending from the anterior surface of the spacer portion towards the posterior surface of the spacer portion,
wherein the length of the through-hole is greater than the width of the plate portion

wherein the plate portion is configured with no more than the first and second holes,
wherein the plate portion further includes extensions with no openings and
wherein the extensions are generally flush with the anterior surface of the plate.

US Pat. No. 9,339,297

FLEXIBLE SPINE STABILIZATION SYSTEM

Globus Medical, Inc., Au...

1. A spine stabilization system, the system comprising:
an elongate connection element extending from a first end portion to a second end portion along a longitudinal axis, the first
and second end portions interconnected by a flexible coupling member,

the elongate connection element comprising a first attachment portion, a second attachment portion, a first resilient member
positioned between the first end portion and the first attachment portion, and a second resilient member positioned between
the first attachment portion and the second attachment portion,

wherein the elongate connection element permits motion of the first attachment portion relative to the second attachment portion,
wherein the first and second attachment portions compress the second resilient member when the first and second attachment
portions move towards each other, and

wherein the first end and first attachment portions compress the first resilient member when the first and second attachment
portions extend away from each other;

a first fixation member operably connected to the first attachment portion, wherein the first fixation member comprises a
first head having a first channel, wherein the first attachment portion is received in the first channel; and

a second fixation member operably connected to the second attachment portion, wherein the first end portion is a free end,
wherein the second fixation member comprises a second head having a second channel, wherein the second attachment portion
is received in the second channel.

US Pat. No. 9,278,008

EXPANDABLE INTERBODY SPACER

GLOBUS MEDICAL, INC., Au...

1. A system for treating a vertebral condition, the system comprising:
an interbody implant configured to transition between a first configuration and a second configuration, wherein the interbody
implant comprises:

a first arm including a first end and a second end, wherein the first arm is defined by a plurality of links coupled to one
another;

a second arm including a first end and a second end, wherein the second arm is defined by a plurality of links coupled to
one another;

a proximal component coupled to the first ends of the first and second arms, wherein the proximal component includes a lumen
with threads;

a distal component coupled to the second ends of the first and second arms; and
a locking feature received in the lumen, wherein the locking feature includes threads that engage the threads of the lumen;
an insertion tool for positioning the implant within a patient, the insertion tool comprising:
an elongate member defining a distal end and a lumen extending therethrough, wherein the elongate member is configured to
releaseably engage the proximal component of the interbody implant; and

a shaft member disposed within the lumen of the elongate member and configured to releasably engage the distal component,
wherein actuation of the insertion tool moves the elongate member relative to shaft member to transition the implant between
first configuration and the second configuration.

US Pat. No. 9,198,770

ARTIFICIAL DISC DEVICES AND RELATED METHODS OF USE

Globus Medical, Inc., Au...

1. A method of installing an artificial disc within a patient, the artificial disc including a superior endplate having a
bi-convex superior surface and a concave inferior surface, an inferior endplate having a bi-convex inferior surface, and a
core assembly secured to the superior endplate and the inferior endplate, wherein the superior endplate and inferior endplate
articulate with respect to each other only by the elasticity of the core assembly, the method including:
forming an opening in a vertebral disc annulus;
removing damaged vertebral disc material through the opening;
inserting the artificial disc between through the opening between a pair of adjacent vertebral bodies; and
securing the artificial disc between the vertebral bodies
wherein securing the artificial disc between the vertebral bodies includes securing a cover plate to at least one of the vertebral
disc annulus and the inner circumference of one of the vertebral bodies to cover the opening.

US Pat. No. 9,198,694

ORTHOPEDIC FIXATION DEVICES AND METHODS OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. A method of stabilizing a spine comprising:
inserting an orthopedic fixation device into a bone, the fixation device including a proximal portion and a distal portion;
attaching a first tulip assembly over the proximal portion of the fixation device, wherein the first tulip assembly is configured
to receive a rod member therein;

removing the first tulip assembly from the proximal portion of the fixation device while the fixation device remains in bone;
and

replacing the first tulip assembly with a second tulip assembly over the proximal portion of the fixation device while the
fixation device remains in bone, wherein the second tulip assembly is configured to receive a rod member therein,

wherein the first tulip assembly or the second tulip assembly is converted from a polyaxial tulip assembly into a uniplanar
tulip assembly by adding a ring element.

US Pat. No. 9,186,258

EXPANDABLE INTERVERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. An implant comprising:
a first endplate including first and second portions hingedly connected together, the first endplate configured to engage
a first bone of the joint and having at least one ramped surface on a side opposite a bone engaging side of the first hinged
portion;

a second endplate including first and second portions hingedly connected together, the second endplate configured to engage
a second bone of the joint and having at least one ramped surface on a side opposite a bone engaging side of the first hinged
portion;

a frame slideably connected to the first hinged portion of the first and second endplates to enable the first hinged portion
of the first and second endplates to move relative to each other at an angle with respect to the longitudinal axis, in connection
with the frame, and the second hinged portions of the first and second endplates to hinge with respect to the respective first
hinged portion to which they are hingedly connected;

an actuator screw rotatably connected to the frame; and
a carriage threadably connected to the actuator screw, whereby rotation of the actuator screw moves the carriage with respect
to the frame and the first and second endplates; and

wherein the carriage comprises a plurality of ramps each mateable with at least one of the at least one ramped surfaces of
the first and second endplates, wherein when the carriage is moved by rotation of the actuator screw, at least one of the
at least one ramped surface of the first endplate and at least one of the at least one ramped surface of the second endplate
each translate along at least one of the plurality of ramps of the carriage to cause the endplates to move relative to each
other in connection with the frame.

US Pat. No. 9,179,953

LOW PROFILE FASTENING ASSEMBLY

GLOBUS MEDICAL, INC., Au...

14. A fastener assembly for fastening an orthopedic device to bone tissue, comprising:
a fastener comprising a head portion and a shank portion for engaging the bone tissue;
a locking head having a cavity for receiving the head portion and at least one protrusion; and
an orthopedic device having an upper surface, a lower surface, and an opening for receiving the locking head and fastener,
the opening having at least one extension, and a radial groove extending from the extension,

wherein the locking head is in a locked position when the at least one protrusion of the locking head is located in the radial
groove of the opening,

wherein the fastener is capable of rotating and polyaxially moving in the locking head after the locking head is received
in the orthopedic device in the locked position,

wherein the locking head extends from the upper surface of the orthopedic device to the lower surface of the orthopedic device.


US Pat. No. 9,125,751

TRANSFORAMINAL PROSTHETIC SPINAL DISC REPLACEMENT AND METHODS THEREOF

GLOBUS MEDICAL, INC., Au...

1. A surgical kit comprising:
a trial; and
a prosthetic disc assembly, the prosthetic disc assembly comprising an upper endplate with an extension portion and a lower
endplate having first and second side rails along and above the length of the lower endplate and defining a first and second
window on opposing sides of the lower endplate

wherein the extension portion of the upper endplate substantially contacts an upper surface of the lower endplate and wherein
the first and second side rails are curved to match a curvature of the upper surface of the lower endplate, thereby creating
the first and second windows having an upper border that is defined by first and second side rails and a lower border that
is defined by a curvature of the lower endplate.

US Pat. No. 9,044,342

EXPANDABLE INTERBODY SPACER

GLOBUS MEDICAL, INC., Au...

1. An expandable interbody spacer comprising:
a first jointed arm comprising a plurality of links pivotally coupled end to end, wherein at least one of the links of the
first jointed arm comprises a first sidewall and a second sidewall, wherein the first sidewall and the second sidewall are
opposed to one another, wherein the first sidewall is on an exterior surface of the first jointed arm, wherein the first sidewall
is straight and transitions into a first rounded portion; and

a second jointed arm comprising a plurality of links pivotally coupled end to end, wherein at least one of the links of the
second jointed arm comprises a third sidewall and a fourth sidewall, wherein the third sidewall and the fourth sidewall are
opposed to one another, wherein the third sidewall is on an exterior surface of the second jointed arm, wherein the third
sidewall is straight and transitions into a second rounded portion, wherein the second jointed arm comprises an opening that
extends through the second rounded portion, wherein the opening of the second jointed arm faces inward into the interbody
spacer and does not extend all the way through the second jointed arm;

a screw having a head and an elongate body extending axially through the expandable interbody spacer from a proximal end to
a distal end, wherein the elongate body of the screw extends into the opening of the second jointed arm, and

wherein the first jointed arm and the second jointed arm are interconnected at a proximal end of the expandable interbody
spacer, wherein the first jointed arm and the second jointed arm are interconnected at a distal end of the expandable interbody
spacer.

US Pat. No. 9,561,113

VERTEBRAL IMPLANTS AND METHODS FOR INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. A polyaxial endplate assembly, comprising:
an articulable plate member comprising a plate portion extending from a rounded compressible body portion, the body portion
defining a cavity therein;

a clamp assembly comprising first and second clamp members each comprising a central receptacle and an interior surface configured
to engage the plate member, wherein the first and second clamp members form a ring, and a securing element configured to be
received within the receptacles of the first and second clamp members, wherein the securing element extends across a greatest
inner diameter of the ring formed by the first and second clamp members; and

a receiving member comprising a convex exterior surface configured to be received within the cavity of the body portion, wherein
the receiving member further comprises at least one inner ledge that is configured to be received within a vertebral implant
body.

US Pat. No. 9,517,343

IMPLANTABLE PULSE GENERATOR THAT GENERATES SPINAL CORD STIMULATION SIGNALS FOR A HUMAN BODY

GLOBUS MEDICAL. INC., Au...

1. An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body, comprising:
a programmable signal generator having a plurality of control registers for storing stimulation signal parameters for a plurality
of channels with each channel capable of being associated with at least two electrodes among a plurality of electrodes, each
channel representing a stimulation signal pattern of the associated electrodes, wherein each electrode among the plurality
of electrodes can be associated with two or more channels;

a processor having a memory;
a treatment control module stored in the memory and executable by the processor, the treatment control module adapted to transmit
the stimulation signal parameters to the programmable signal generator for storage in the plurality of control registers,
wherein the programmable signal generator generates the stimulation signals to drive the plurality of electrodes according
to the stored signal parameters independently from the processor while the processor is in a standby mode;

a timing generator adapted to generate timing signals representing stimulation signals for the plurality of channels according
to the stored stimulation signal parameters; and

an arbitrator that continuously receives the generated timing signals and selects one channel among the plurality of channels
as an active treatment channel.

US Pat. No. 9,517,347

IMPLANTABLE PULSE GENERATOR THAT GENERATES SPINAL CORD STIMULATION SIGNALS FOR A HUMAN BODY

GLOBUS MEDICAL, INC., Au...

1. An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body, comprising:
a signal generator for generating the stimulation signals, said signal generator comprising:
an arbitrator;
a high frequency generator;
control registers storing stimulation signal parameters for a plurality of channels with each channel capable of being associated
with at least two electrodes among a plurality of electrodes, each channel representing a stimulation signal pattern of the
associated electrodes;

a timing generator adapted to generate timing signals representing stimulation signals for the plurality of channels according
to the stored signal parameters;

an electrode driver for each electrode, and adapted to adjust an amplitude of the timing signals from the timing generator
according to the stored signal parameters and output an output current corresponding to the adjusted signals for transmission
to the associated electrode so as to enable independent control of the amplitude of the stimulation signal for each said channel,

wherein a register bus is configured to allow electronic communication between the arbitrator, the high frequency generator,
the timing generator, and the electrode driver for each electrode; and

a treatment control module configured to instruct the signal generator to generate the stimulation signals while a microcontroller
electrically connected to the signal generator is in standby mode.

US Pat. No. 9,510,843

DISCECTOMY INSTRUMENT

Globus Medical, Inc., Au...

1. A discectomy instrument for removing a portion of an intervertebral disc, comprising:
a scraper;
a drive shaft operably attached to the scraper;
a ball joint coupled to the scraper at one end and to the drive shaft at the other end, wherein the scraper is connected to
the ball joint; and

a barrel, wherein the drive shaft is removably connected to the barrel and capable of transmitting torque, and
wherein the scraper is configured to pivot as well as rotate with the drive shaft.

US Pat. No. 9,511,227

IMPLANTABLE PULSE GENERATOR THAT GENERATES SPINAL CORD STIMULATION SIGNALS FOR A HUMAN BODY

GLOBUS MEDICAL, INC., Au...

1. An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body, comprising:
a programmable signal generator having a plurality of control registers for storing stimulation signal parameters and adapted
to generate the stimulation signals based on the stored signal parameters;

a processor having a memory; and
a treatment control module stored in the memory and executable by the processor, the treatment control module adapted to transmit
the stimulation signal parameters to the programmable signal generator for storage in the plurality of registers and to place
the processor in a standby mode,

wherein the programmable signal generator generates the stimulation signals to drive a plurality of electrodes according to
the stored signal parameters independently from the processor while the processor is in the standby mode.

US Pat. No. 9,498,558

BIODEGRADEABLE PUTTY COMPOSITIONS AND IMPLANT DEVICES, METHODS, AND KITS RELATING TO THE SAME

Globus Medical, Inc., Au...

1. A method of preparing a carrier composition comprising:
combining at least one polymer component and at least one phospholipid component to form a carrier composition;
combining the carrier composition with one or more active ingredients selected from the group consisting of ceramic beads,
particulates, granules, calcium phosphate particles, hydroxyapatite particles, silicated hydroxyapatite particles, bioactive
glass particles, cancellous chips, cortical bone chips, and demineralized bone matrix chips; and

mixing the carrier composition with blood or bone marrow aspirate.

US Pat. No. 9,486,326

INTERVERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. An intervertebral spacer for therapeutic treatment of a patient, comprising:
a link sized and dimensioned to fit within an intervertebral space in the patient and configured to maintain a separation
of two adjacent vertebrae for a period of time;

a rigid guiding object insertable into the patient, the rigid guiding object and the link sized to be insertable into the
patient using a minimally invasive surgical (MIS) approach;

a pivot pin rotatably retained within a mating chamber formed within the link, wherein the pivot pin is reversibly mateable
with the guiding object so that the link may be inserted into the patient, and the pivot pin is rotatable such that an orientation
of the link may be changed during or after insertion; and

a radiused nut retained within a mating radiused chamber formed within the pivot pin,
wherein the radiused nut moves with the pivot pin.

US Pat. No. 9,370,432

SPINE STABILIZATION DEVICE AND METHODS

GLOBUS MEDICAL, INC., Au...

1. A surgical method comprising:
inserting an implant between adjacent vertebrae, wherein the implant comprises:
a first support component having a first side adapted to engage a first vertebra of a patient, and a second side opposite
the first side;

a core having a third side having a smooth surface in engagement with the second side, said core further including a fourth
side opposite the third side;

a second support component having a fifth side adapted to engage the fourth side, and a sixth side opposite fifth side adapted
to engage a second vertebra of the patient;

wherein when said first support component is engaged to the first vertebra and said second support component is engaged to
the second vertebra, and said core is positioned between said first and second support components, the first and second adjacent
bones are stabilized, and said core may move to enable a kinematic movement of the two adjacent bones similar to a natural
kinematic movement of the bones,

wherein a portion of the fifth side of the second support is generally planar and a portion of the fourth side of the core
is generally planar,

wherein a portion of the second side of the first support has a curved portion and a portion of the third side of the core
has a curved portion, and

wherein a pin extends through the second support component and the core to attach the second support component to the core.

US Pat. No. 9,302,108

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC., Au...

1. The spinal cord stimulation device comprising:
an implantable pulse generator;
a plurality of implantable stimulation electrodes;
an external charger having a primary charging coil;
a clinician programmer application provided on a computing device; and
a communication device allowing communication between the computing device and an optional mobile device and the implantable
pulse generator and an optional trial implantable pulse generator,

the implantable pulse generator comprising:
a circuit board comprising a plurality of output capacitors, an application specific integrated circuit and a microcontroller,
the microcontroller in communication with the communication device and with the application specific integrated circuit;

a rechargeable battery;
an antenna; and
a secondary charging coil
a plurality of locking housings each locking housing defining an aperture, the aperture configured to accept a silicone tube
and the silicone tube configured to accept the lead, and wherein the locking housing further defines a second aperture configured
to accept a compression lead lock mechanism; and

a plurality of lead contacts, each lead contact separated from an adjacent lead contact by a silicone seal, wherein the lead
contacts are configured in stacks of up to 8 lead contacts and each stack is connected at one end to one locking housing and
wherein the lead contacts connect to the feedthrough.

US Pat. No. 9,192,481

EXPANDABLE VERTEBRAL PROSTHESIS

Globus Medical, Inc., Au...

1. An expandable prosthetic implant device for engagement between vertebrae, comprising:
an inner member having a hollow interior portion, the hollow interior portion including a plurality of teeth, and including
a first end portion configured to engage a first vertebral body;

an outer member having a hollow interior portion configured to coaxially receive a portion of the inner member therein and
including a second end portion configured to engage a second vertebral body, wherein the inner and outer members are moveable
relative to each other along a longitudinal axis;

a gear member positioned between the inner member and outer members and capable of rotating along an axis that is perpendicular
to the longitudinal axis,

wherein the hollow interior portion of the outer member includes a plurality of teeth,
wherein the gear member engages the teeth of the inner member and the teeth of the outer member, and
wherein rotation of the gear member causes the outer member to move relative to the inner member along the longitudinal axis.

US Pat. No. 9,050,145

SYSTEM AND METHOD FOR FACET JOINT REPLACEMENT

Globus Medical, Inc., Au...

1. An implantation system comprising:
a left fixation member implantable in a first vertebra;
a right fixation member implantable in the first vertebra;
a crosslink operably connected to the left fixation member and the right fixation member, wherein the crosslink comprises
a half-pipe body;

a left inferior implant operably connected to the crosslink, the left inferior implant comprising a left inferior articular
surface; and

a right inferior implant operably connected to the crosslink, the right inferior implant comprising a right inferior articular
surface,

wherein the left inferior implant comprises an inferior strut securable to the left fixation member and the crosslink, wherein
the left inferior implant further comprises an attachment mechanism comprising a saddle to permit insertion of the crosslink
into the saddle.

US Pat. No. 10,070,899

LATERAL SPINOUS PROCESS SPACER WITH DEPLOYABLE WINGS

Globus Medical Inc, Audu...

1. An implant for positioning between adjacent spinous processes comprising:an elongate body having a longitudinal axis, the elongate body including a leading end portion, a trailing end portion, and a central support portion disposed between the leading and trailing end portions, wherein the trailing end portion includes a flange defining a sidewall configured and dimensioned to contact at least one of the adjacent spinous processes;
one or more tabs attached to the leading end portion; and
a gear barrel insert extending through the trailing end portion and the central support portion,
wherein the one or more tabs are actuatable by the rotatable gear barrel insert such that when the gear barrel insert is rotated, the tabs extend outwardly from the leading end portion, and
wherein the leading end portion extends from a proximal portion to a distal portion, and the one or more tabs are rotatably attached to the proximal portion of the leading end portion.

US Pat. No. 9,526,527

PEDICLE SCREW HAVING A REMOVABLE ROD COUPLING

Globus Medical, Inc., Au...

1. A pedicle screw for spinal fixation comprising:
a bone fastener portion, wherein the bone fastener portion is at least partially threaded;
a permanent rod coupling comprising:
a bottom surface connected to the bone fastener portion, a middle section positioned between the bottom surface and a top
surface, a lateral rod opening in a portion of the middle section adapted to receive a permanent rod, a threaded bore that
extends from the top surface into the lateral rod opening, a permanent rod fastener mated to fit the threaded bore to extend
into the lateral rod opening, wherein the permanent rod fastener can engage a permanent rod positioned in the lateral rod
opening, and a transition region on a portion of the top surface;

a breakaway portion in the transition region;
a temporary rod coupling connected to the transition region, wherein the temporary rod coupling comprises a temporary rod
channel adapted to receive a temporary rod, an upper threaded opening that extends into the temporary rod channel, and an
upper rod fastener mated to the upper threaded opening, wherein the upper rod fastener can engage the temporary rod positioned
in the temporary rod channel;

wherein the permanent rod is positioned in the lateral rod opening and secured by the permanent rod fastener, wherein the
permanent rod can be inserted into the lateral rod opening along a direction which is transverse to a longitudinal axis of
the permanent rod and transverse to a longitudinal axis of the bone fastener portion, and the temporary rod is temporarily
positioned in the temporary rod channel and secured by the upper rod fastener and when the temporary rod is not needed the
temporary rod coupling can be removed at the transition region by separation at the breakaway portion to leave the top surface.

US Pat. No. 9,492,289

EXPANDABLE INTERVERTEBRAL IMPLANT

GLOBUS MEDICAL, INC., Au...

1. An implant for placement between bones, the implant defining a longitudinal axis extending between distal and proximal
ends, the implant comprising:
a first endplate configured to engage a first bone, and having an opening through the endplate, and at least one ramped surface
on a side opposite a bone engaging side;

a second endplate configured to engage a second bone, and having an opening through the endplate, and at least one ramped
surface on a side opposite a bone engaging side;

a frame at least partially surrounding at least a portion of the first endplate;
a carriage having an open area at least partially aligned with the openings in the first and second endplates;
an actuator screw engaging the carriage; and
a blocking mechanism configured to prevent backing out of a fastener passed through at least one of the first and second endplates
and into one of the first or second bones, the blocking mechanism including a blocking member moveably retained within a channel
between an unblocking position and a blocking position in which a portion of the blocking member overlaps a portion of the
fastener,

whereby rotation of the actuator screw moves the carriage with respect to the frame and the first and second endplates; and
wherein the carriage comprises a plurality of ramps each engageable with at least one of the at least one ramped surfaces
of the first and second endplates, wherein when the carriage is moved by rotation of the actuator screw, at least one of the
at least one ramped surface of the first endplate and at least one of the at least one ramped surface of the second endplate
each move along at least one of the plurality of ramps of the carriage to cause the endplates to move relative to each other
in connection with the frame,

wherein the implant has a length extending from the distal end to the proximal end of the implant and a width extending perpendicular
to the length, the width of the implant is greater than the length of the implant.

US Pat. No. 9,451,990

FACET JOINT REPLACEMENT INSTRUMENTS AND METHODS

GLOBUS MEDICAL, INC., Au...

1. A method of positioning an inferior facet joint replacement component, the method comprising:
implanting a superior facet joint replacement implant to replace a natural superior articular facet on a first vertebra of
a spine;

coupling the inferior facet joint replacement component to an inserter tool; and
engaging a first coupling portion of the inferior component with a complementary first coupling portion of the superior implant
to couple the inferior component to the superior implant in a predetermined orientation, wherein the first coupling portion
of the inferior component comprises a clip having a pair of pins separated from a pair of prongs,

wherein the pair of pins are shaped to engage the superior facet joint replacement implant and the pair of prongs are shaped
to engage the inferior facet joint replacement component, and

wherein the pair of pins are cylindrical and have a constant diameter over their entire length and the pair of prongs are
configured as flanges, correspond to a gripping feature on the inferior facet joint implant, and are separated by a slot substantially
centered between the pair of prongs to enable the pair of prongs to independently move with respect to each other.

US Pat. No. 9,427,262

METHOD FOR STABILIZING THE SPINE

Globus Medical, Inc., Au...

1. A surgical method comprising:
inserting a first anchor into a first pedicle adjacent to one spinal segment;
inserting a second anchor into a second pedicle adjacent to the one spinal segment;
inserting a third anchor into a third pedicle adjacent to the one spinal segment;
inserting a fourth anchor into a fourth pedicle adjacent to the one spinal segment; and
attaching a stabilization member into each of the first, second, third and fourth anchors, wherein the stabilization member
comprises:

a first elongate member;
a second elongate member; and
a connector portion between the first elongate member and the second elongate member, wherein the connector portion comprises
a first end having a first opening for receiving the first elongate member and a second end having a second opening for receiving
the second elongate member, and wherein the first end of the connector portion has a first width profile adjacent to the first
elongate member that is smaller than a second width profile that is further removed from the first elongate member.

US Pat. No. 9,358,046

ROD COUPLING SYSTEM AND DEVICES AND METHODS OF MAKING AND USING THE SAME

Globus Medical, Inc., Au...

1. A rod coupler system comprising:
a coupling body having a bone fastener disposed therethrough,
a first saddle detachably attached to a locking cap, the first saddle having a concave portion configured to abut an elongate
rod along at least two lines of contact between said first saddle and said elongate rod, and

a second saddle having a first side abutting said bone fastener within said coupling body, and a second side of said saddle
opposite said first side, said second side having a concave portion configured to abut the elongate rod along at least two
lines of contact between said second saddle and said elongate rod,

wherein in a first assembled position, the first saddle is attached to the locking cap and in a second assembled position,
the first saddle is not attached to the locking cap.

US Pat. No. 9,204,972

ARTICULATING EXPANDABLE INTERVERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. A spacer for separating bones of a joint, the spacer comprising:
a frame;
a carriage slideably moveable in relation to the frame, and having at least one ramped surface;
an actuating screw connected to the carriage and supported by the frame, the actuating screw configured to cause the carriage
to slideably move in relation to the frame when the actuating screw is rotated;

a first endplate configured to engage a first bone of the joint, and having at least one ramped surface mateable with the
at least one carriage ramped surface, whereby when the carriage is slideably moved by rotation of the actuating screw, the
at least one endplate ramped surface slides against the at least one carriage ramped surface to cause the first endplate to
move along an axis transverse to a longitudinal axis, to increase a height of the spacer; and

a second endplate configured to engage a second bone of the joint,
a screw support connected to the frame and configured to retain the actuating screw
wherein the screw support is configured to change an angular orientation between the actuating screw and the frame.

US Pat. No. 9,173,747

EXPANDABLE VERTEBRAL PROSTHESIS

Globus Medical, Inc., Au...

1. A method for stabilizing spinal elements comprising the steps of:
providing an expandable prosthetic implant, the expandable prosthetic implant comprising:
an inner member having a hollow interior portion and a threaded external portion and including a first end portion configured
to engage a first vertebral body;

an outer member having a hollow interior portion configured to coaxially receive the inner member therein and including a
second end portion configured to engage a second vertebral body, a second member including a second end portion configured
to engage a second vertebral body, wherein the inner and outer members are moveable relative to each other along a longitudinal
axis;

a gear member positioned coaxial to the inner member and outer member and axially fixed to the outer member and freely rotatable
with respect to the outer member, the gear member configured with a plurality of notches,

a locking assembly having a flexible member positioned between the inner member and the outer member and movable between a
first position and a second position, and wherein in the first position one end of the flexible member engages with one of
a plurality of notches configured on an inner surface of the gear member to block movement of the gear member, and in the
second position the flexible member is disengaged from one of the plurality of notches and allows movement of the gear member
which allows relative movement between the inner member and the outer member,

accessing the first and second vertebral bodies; and
positioning the expandable prosthetic implant between the first and second vertebral bodies.

US Pat. No. 9,131,962

BONE SCREW ASSEMBLY

GLOBUS MEDICAL, INC., Au...

1. A bone stabilization system comprising:
a coupling member, wherein the coupling member comprises an upper surface and a lower surface;
a screw member configured to be received in the coupling member, wherein the screw member is downwardly delivered into the
coupling member such that it passes the upper surface the coupling member and moves in a direction from the upper surface
to the lower surface of the coupling member;

a wedge member configured to be received in the coupling member, wherein the wedge member includes a bottom surface and a
top surface that is non-parallel to the bottom surface;

a rod implant configured to be received in the coupling member; and a locking assembly configured to secure the rod implant
within the coupling member; and

a coupling body component having one or more slits to assist in securing the screw member to the coupling member, wherein
the coupling body component is independent from the coupling member, wherein the coupling body component is downwardly delivered
into the coupling member such that it passes the upper surface of the coupling member and moves in a direction from the upper
surface to the lower surface of the coupling member.

US Pat. No. 9,044,275

CERVICAL SPINE STABILIZATION SYSTEM WITH EXTENDABLE PLATES

GLOBUS MEDICAL, INC., Au...

1. A spine stabilization system comprising:
a base plate having a plurality of screw holes and a plurality of corresponding screw locking mechanisms, wherein the base
plate screw holes extend from atop surface of the base plate to a bottom surface of the base plate;

an extension plate having a plurality of screw holes and corresponding screw locking mechanisms, wherein the extension plate
screw holes extend from a top surface of the extension plate to a bottom surface of the extension plate,

wherein the extension plate is dimensioned and configured with an extension portion, the extension portion having a screw
hole and a screw locking mechanism and a finger portion having a connection element to couple with the base plate, wherein
the finger portion comprises a hook element having downwardlv curved surface that creates a recess for the base plate, wherein
an upper surface of the hook element is in contact with a lower surface of the base plate when the base plate is received
in the recess of the hook element,

wherein the base plate is provided with graft windows having edges, wherein one of the edges is configured to receive and
couple with the connection element,

wherein the extension plate is positioned over the base plate such that a bottom surface of the extension plate is in contact
with a top surface of the base plate when the extension plate is joined to the base plate.

US Pat. No. 9,770,340

MULTI-PIECE INTERVERTEBRAL IMPLANTS

GLOBUS MEDICAL, INC., Au...

1. An intervertebral implant for implantation in an intervertebral space comprising:
a first layer of cortical bone having a superior surface for contacting a first vertebral body;
a second layer of cortical bone having an inferior surface for contacting a second vertebral body, wherein the second layer
is operably attached to the first layer; and

a bore hole that extends through at least a portion of the first layer and the second layer, wherein the bore hole has a first
end that opens at one of either the superior surface of the first layer or the inferior surface of the second layer and a
second end that is completely blocked by one of either the first layer or the second layer,

wherein the superior surface is separated from the inferior surface by a plurality of sidewalls each formed of cortical bone,
wherein the first layer of cortical bone is in direct contact with the second layer of cortical bone, and
wherein the cortical bone of the second layer and the cortical bone of the first layer contact each other at an interface.

US Pat. No. 9,585,760

FACET ARTHOPLASTY DEVICES AND METHODS

Globus Medical, Inc., Au...

1. A prosthetic system comprising:
a bar member comprising a left side region and a right side region, wherein the bar member comprises a track;
a first fixation area on the left side region;
a second fixation area on the right side region;
a first fixation element received in the first fixation area;
a second fixation element received in the second fixation area;
a first facet joint structure element positioned nearer to the first fixation area than the second fixation area; and
a second facet joint structure element positioned nearer to the second fixation area than the first fixation area, wherein
the first facet joint structure and the second facet joint structure are each received within the track.

US Pat. No. 9,549,763

ORTHOPEDIC FIXATION DEVICES AND METHODS OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. A method of installing an orthopedic fixation device comprising:
inserting a locking clamp assembly into a bore in a coupling element, wherein the locking clamp assembly comprises a wedge
element and a clamp element secured to the wedge element;

moving the locking clamp assembly through the bore in the coupling element until a recessed surface on the wedge element engages
a protuberance on an interior surface of the coupling element to secure the locking clamp assembly in the coupling element;

inserting a head of a bone fastener into the clamp element such that the clamp element engages the head; and
moving the wedge element downward past the protuberance on the interior surface of the coupling element such that exterior
surfaces of the clamp element engage the interior surface of the coupling element forcing the clamp element to clamp onto
the head of the bone fastener to secure the bone fastener in the coupling element,

wherein the wedge element comprises downwardly extending tabs configured to be received in corresponding slots in the head
of the bone fastener.

US Pat. No. 9,550,062

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC, Aud...

1. A spinal cord stimulation device comprising:
an implantable pulse generator comprising:
a circuit assembly housed in a casing, the circuit assembly including a plurality of output capacitors positioned within the
implantable pulse generator, only one application specific integrated circuit (ASIC) and a microcontroller, wherein the circuit
assembly further comprises a plurality of timing generators and an arbitrator that is designed to suppress activity from one
or more of the timing generators when one or more of the timing generators are active;

at least one rechargeable implantable battery housed in the casing and operably connected with the circuit assembly;
an external charger comprising:
a primary charging coil;
at least one battery; and
a circuit board operably connected with the primary coil and the at least one rechargeable battery,
wherein the at least one rechargeable battery in the implantable pulse generator is recharged using transcutaneous power transmissions
between the primary charging coil and the secondary charging coil,

wherein the only one application specific integrated circuit comprises an analog and a digital circuit, and
wherein the only one application specific integrated circuit comprises circuitry configured to generate a high speed burst
pulse that is combined with a stimulation pulse to generate a bursted bi-phasic pulse train.

US Pat. No. 9,504,506

DEVICES AND METHODS FOR VERTEBROSTENTING

GLOBUS MEDICAL, INC., Au...

1. An apparatus for treating a vertebral body comprising:
a handle;
a flexible shaft assembly extending from a distal end of the handle, wherein the flexible shaft assembly comprises a compression
spring and a band retention element; and

a lever and cam sub assembly for varying a force used to apply a curvature to a distal end of the flexible shaft assembly,
wherein the lever has a first position that is against the handle and a second position that is away from the handle, wherein
the lever and cam sub assembly comprises a cam and a cam pusher assembly having a proximal-most end and a distal end, wherein
the cam is egg-shaped having an outer surface wall with a small radius side and a large radius side, wherein the cam pusher
assembly is in contact with an outer most surface of the cam, and the band retention element is positioned outside of the
cam, wherein in the first position, the small radius side of the cam contacts the proximal-most end of the cam pusher assembly,
and when the lever is moved from the first position to the second position, the large radius side of the cam contacts the
proximal-most end of the cam pusher assembly to linearly translate the cam pusher assembly along a length of the apparatus.

US Pat. No. 9,492,665

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC., Au...

1. A spinal cord stimulation device comprising:
an implantable pulse generator comprising:
a circuit board comprising a plurality of output capacitors, an application specific integrated circuit, and a microcontroller,
wherein the microcontroller is operably connected with the output capacitors and the application specific integrated circuit;

a positive digital to analog convertor;
a negative digital to analog convertor wherein the positive digital to analog convertor and the negative digital to analog
convertor are configured not to be active concurrently;

a secondary charging coil; and
a voltage doubler full wave rectifier configured to convert a full wave of an induced AC voltage into a usable DC voltage;
and

a rechargeable implantable grade lithium ion battery configured to be inductively charged by a Constant Current, Constant
Voltage type of regulation of the usable DC voltage;

a plurality of implantable stimulation electrodes, each operably connected to at least one of a plurality of implantable leads
which are configured to be electrically connected to the implantable pulse generator;

an external charger having a primary charging coil configured to provide the induced AC voltage to the secondary charging
coil;

a wireless communication device configured to provide communication with the implantable pulse generator via the RF antenna;
and

an alignment sensor for aligning the external charger to the implantable pulse generator by measuring a reflected impedance.

US Pat. No. 9,408,651

CEMENT-DIRECTING ORTHOPEDIC IMPLANTS

GLOBUS MEDICAL, INC., Au...

13. A surgical method comprising:
inserting a device into a cavity of a patient, the device being in a compressed shape;
expanding the device to an expanded shape, wherein the device comprises a compressible, shape-restoring hollow mesh structure,
wherein said mesh structure has regions of different permeability, and wherein said mesh structure is a co-braided structure
comprising primary members and secondary members occupying interstices between said primary members, and wherein the device
further comprises one or more windows; and

inserting bone cement into the device, wherein the mesh structure creates added flow resistance to the bone cement inserted
into the device, and the windows direct the flow of bone cement placed in the device toward preferred directions.

US Pat. No. 9,357,988

SPINAL SURGERY DISTRACTION WITH AN INTEGRATED RETRACTOR

Globus Medical, Inc., Au...

1. A method of assembling a distractor retractor assembly, the method comprising:
securing a distractor rod to a proximal end of a distractor head, wherein a distal end of the distractor head has a tapered
profile between the distal end and the proximal end constructed and arranged for insertion between adjacent vertebral bodies,
the distal head includes a plurality of side faces positioned between the distal end and the proximal end, and a keyed shaped
projection is secured to one of the side faces; and

engaging the distractor head on a distal tip of a retractor, the distal tip being constructed and arranged for insertion between
adjacent vertebral bodies, the distal tip of the retractor including a keyway having a beveled shape and the keyed shaped
projection of the distractor head has a profile which is constructed and arranged to engage and cooperate with the keyway
to operatively connect the distractor head to the retractor.

US Pat. No. 9,320,547

ADJACENT LEVEL FACET ARTHROPLASTY DEVICES, SPINE STABILIZATION SYSTEMS, AND METHODS

GLOBUS MEDICAL, INC, Aud...

1. An implantable spinal device comprising:
a spinal fixation member configured to extend along a first vertebra and a second vertebra of a spine, the spinal fixation
member comprising first and second attachment mechanisms adapted to attach the spinal fixation member to the first and second
vertebrae, respectively;

a facet replacement member coupled to the spinal fixation member and to a third vertebrae, wherein the facet replacement member
is coupled to the spinal fixation member between the first and second attachment mechanisms of the spinal fixation member,
the facet replacement member configured to provide movement between the first or second vertebrae and the third vertebra,
the facet replacement member comprising an anchoring mechanism adapted to attach at least a portion of the facet replacement
member to the third vertebra,

wherein the spinal fixation member is a fusion member configured to promote fusion between the first and second vertebrae,
wherein the facet replacement member comprises a crossbar having first and second ends and the facet replacement member further
comprises first and second bearing elements, and when implanted, the first end of the crossbar is seated in the first bearing
element, the second end of the crossbar is seated in the second bearing element, and the crossbar is able to move in the bearing
elements,

wherein the facet replacement member anchoring mechanism comprises first and second bone engaging elements connected to the
crossbar,

wherein first and second arms extend between the first and second bone engaging elements and the crossbar, and wherein
the first and second arms are connected to the crossbar between the first and second ends of the crossbar, and the distance
between the first and second arms along the crossbar is adjustable.

US Pat. No. 9,216,095

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. An intervertebral implantation system comprising:
a fusion device having a longitudinal axis, the fusion device capable of expansion and contraction, wherein the fusion device
comprises:

a first endplate;
a second endplate; and
a one piece translation member positioned between the first endplate and second endplate, wherein the translation member includes
first and second surfaces for engaging the first endplate and third and fourth surfaces for engaging the second endplate;
and

an actuation member received in the translation member, wherein rotation of the actuation member causes translation of the
translation member such that first and second surfaces of the translation member engage the first endplate and the third and
fourth surfaces of the translation member engage the second endplate to cause a change in a distance of separation between
the first endplate and second endplate resulting in an expansion or contraction of the fusion device,

wherein the first and second surfaces of the translation member are separated by a bridge portion,
wherein the bridge portion defines a through opening extending along a second axis that is transverse to the longitudinal
axis.

US Pat. No. 9,138,271

SECURING FASTENERS

Globus Medical, Inc., Au...

1. A fastener insertable within an implant in a body, the implant having an aperture through which the fastener may be inserted,
the aperture defining a larger dimension and a smaller dimension, the fastener comprising:
an elongated body;
a head connected to said body, said head further including a circumferential groove disposable proximate the larger dimension
of the implant when said head is mated with said implant; and

a locking member sized to be positionable partly within said circumferential groove to extend from said circumferential groove
to thereby increase a widest dimension of said head, said locking member formed with a resilient material, said locking member
resiliently expandable from a first compressed configuration having a first dimension to a second relaxed configuration having
a second dimension, said second dimension larger than said first dimension,

said head passable into the aperture when said locking member is assembled into said groove and said locking member is in
said first compressed configuration, and said head not passable out of the aperture when said locking member is resiliently
expanded to said second configuration, due to said locking member interfering in said second configuration with the smaller
dimension of the curved inner profile;

said locking member further including a first end and a second end, said first end fixed within said circumferential groove,
and said second end moveable to change a shape of said locking member from said first compressed configuration to said second
relaxed configuration, said second end including a notch releasably engageable to maintain said locking member in said first
compressed configuration.

US Pat. No. 9,138,325

LAMINA IMPLANT AND METHOD

GLOBUS MEDICAL, INC., Au...

1. A method for lamina replacement and restoration, comprising:
a. performing a laminectomy to remove a portion of a lamina of a spine;
b. converting the lamina into autologous bone;
c. filling an implant having a hollow interior with the autologous bone, the implant having a first arm, a second arm and
a hinge, the first arm and the second arm movably engaged to each other through the hinge;

d. adjusting the hinge so that one or more ends of the implant may be positioned before being secured to a spine;
e. locking the hinge to lock the orientation of the first arm relative to the second arm; and
f. securing the implant to a spine at a site of the laminectomy
wherein the hollow interior of the implant extends from the hinge to a distal end of the first arm and distal end of the second
arm.

US Pat. No. 10,058,394

ROBOT ARM AND METHODS OF USE

GLOBUS MEDICAL, INC., Au...

11. A method of moving a robot arm comprising:depressing a primary button on an activation assembly;
applying force to the activation assembly;
sensing the force with a load cell;
communicating force to a computer processor; activating motors within robot arm using the computer processor; and
moving the robot arm with the motors in the direction of the applied force,
wherein the primary button comprises a ridge encircling an end effector coupled to the robot arm, the end effector holding a surgical tool.

US Pat. No. 9,808,293

ORTHOPEDIC CLAMP AND EXTENSION ROD

GLOBUS MEDICAL, INC., Au...

1. A system for extending a pre-existing spinal implant, the system comprising:
an existing elongated rod connected to a bone anchor,
an extension clamp including a monolithic yoke having a first end and a second end, the yoke comprising first and second rod
engaging portions and a channel between the first and second rod engaging portions, the second end being spaced apart from
the first end, and an extension rod extending from the second end of the yoke,

wherein the yoke receives the bone anchor such that the bone anchor is positioned in the channel between the first and second
rod engaging portions,

wherein the extension clamp is connected to the existing elongated rod by engaging the first and second rod engaging portions
of the yoke with the existing elongated rod and securing first and second set screws extending through the first and second
rod engaging portions, respectively, to the existing elongated rod.

US Pat. No. 9,566,094

OCCIPITAL PLATE SYSTEMS

Globus Medical, Inc., Au...

1. An occipital plate system comprising:
an occipital plate, the occipital plate having an upper portion and a lower portion;
an articulating joint member comprising a housing having a first end and a second end;
an extension member operably attached to the lower portion of the occipital plate at a first end and to the articulating joint
member at a second end; and

a first clamping arm extending from the first end of the housing of the articulating joint member and configured to articulate
and a second clamping arm extending from the second end of the housing of the articulating joint member and configured to
articulate,

wherein the first and second clamping arms are configured to move toward one another to lock the first and second clamping
arms into position,

wherein the first and second clamping arms comprise a plurality of teeth that extend along an inner surface of the first and
second clamping arms to grip on to vertebral bone as the first and second clamping arms are moved medially inward, and

wherein the articulating joint member includes a set screw operably attached to a locking wedge, wherein a portion of the
locking wedge includes tapers configured to engage a taper portion formed in each of the first and second clamping arms, such
that rotation of the set screw causes the tapers on the locking wedge to engage the tapered portions of the first and second
clamping arms moving the first and second clamping arms toward one another and locking the first and second clamping arms
into position.

US Pat. No. 9,526,538

METHODS AND APPARATUS FOR TREATING VERTEBRAL FRACTURES

GLOBUS MEDICAL, INC., Au...

1. A method for treating bone, comprising:
creating a first cavity in the bone;
creating a second cavity in the bone;
introducing an inflated first balloon into the second cavity;
introducing a first containment jacket into the first cavity while the first balloon remains inflated in the second cavity
to prevent loss of vertebral height, wherein the first containment jacket is introduced via a tubular member having a tubular
hub, wherein the first containment jacket includes a neck placed over a tip of a distal end of the tubular member, wherein
a mandrel assembly is disposed within the tubular member, wherein the mandrel assembly comprises a stem and a mandrel hub,
wherein the mandrel hub is proximal and extends around the tubular hub, and the stem has an enlarged portion extending through
the tubular member, a narrowed portion extending through the first containment jacket, and an enlarged blunt nose positioned
at a distal end of the first containment jacket;

introducing filler material into the first containment jacket in the first cavity while the first balloon remains inflated
in the second cavity;

deflating and removing the first balloon from the second cavity;
introducing a second containment jacket into the second cavity; and
introducing filler material into the second containment jacket.

US Pat. No. 9,492,206

INTERSPINOUS LIGAMENT TRANSVERSE CONNECTOR

Globus Medical, Inc., Au...

1. A cross connector system for stabilizing the spine comprising:
a first elongate rod and a second elongate rod;
a third elongate rod connecting the first and second elongate rods;
a one-piece connecting body comprising a first elongated portion having first and second ends, a second elongated portion
having first and second ends, wherein the first end of the first elongated portion comprises a receptacle facing outwards
towards the first rod and away from the second rod and the second end of the second elongated portion comprises a clamp, the
clamp comprising an upper clamp portion and a lower clamp portion and an opening therebetween;

a first set screw selectively positioned to securely hold the connecting body to the first rod; and
a second set screw selectively positioned to securely hold the connecting body to the third rod,
wherein the second set screw is located at the second end of the second elongated portion and the first set screw is located
at the first end of the first elongated portion,

wherein when the first and second set screws are secured to the connecting body, the second set screw and first set screw
are offset both vertically and horizontally along a plane that is perpendicular to a central longitudinal axis of one of the
first set screw and second set screw,

wherein the clamp allows the connecting body to slidingly engage with the third rod;
wherein the second set screw causes the clamp to be clamped around the third rod, thereby locking the third rod relative to
the connecting body, and

wherein the third rod is configured and designed with frusto-conical tips configured for puncturing an interspinous ligament.

US Pat. No. 9,474,560

LOAD DISTRIBUTION CROWN

GLOBUS MEDICAL, INC, Aud...

1. A surgical method comprising: providing a fastener having a head member and a shaft member; providing a crown, wherein
the crown comprises an upper surface, a bottom surface and an opening formed between the upper and bottom surfaces, wherein
the crown further comprises a slit formed in the crown, wherein the slit extends from the upper surface to the bottom surface,
wherein the slit extends from an outer most surface of the crown to the opening in the crown; and inserting the fastener through
the opening of the crown and into a bone member, wherein the head member of the fastener applies a pressure to the surface
of the crown to cause deformation of the crown, thereby causing free ends of the crown to move toward a common plane, wherein
the first free end or the second free end comprise one or more protrusions configured and dimensioned to interfere with a
portion of the opposing free end to provide tactile or audible feedback to a user, wherein as the fastener is inserted into
bone, the deformation of the crown allows for increasing load distribution by the crown on the surface of the bone.

US Pat. No. 9,468,537

METHOD AND IMPLANT DEVICE FOR GRAFTING ADJACENT VERTEBRAL BODIES

Globus Medical, Inc., Au...

1. An implant device for grafting together adjacent bony structures of a body comprising:
an endplate having an inner disc portion and outer ring portion spaced from the inner disc portion by a connecting wall disposed
there between, wherein an upper surface of the endplate includes a retaining structure adapted for securing the endplate to
one of the bony structures, and the endplate inner disc portion has an integrally formed socket, half-socket, or poly-axial
head,

a one-piece ball joint rod having a longitudinally extending body and a first end and a second end, wherein at least a portion
of the ball joint rod first end and second end is curvilinear in shape, and the curvilinear ball joint rod first end and second
end are rotatably disposed in the endplate socket, half-socket, or poly-axial head to fixedly interconnect the bony structures;
and

a fusion shaft member disposed on the ball joint rod body, wherein the fusion shaft member includes a body having a c-shape.

US Pat. No. 9,358,050

ORTHOPEDIC ANCHOR ASSEMBLY

GloBus Medical, Inc., Au...

1. An orthopedic assembly comprising:
a plate member having an aperture;
an anchor insertable through the aperture of the plate member, the anchor having a plurality of arms separated by grooves;
and

a locking mechanism including a plurality of fingers corresponding to each of the arms,
wherein each of the arms of the anchor includes a slot formed on an inner surface of the arm, wherein each of the slots is
formed through an upper surface of its respective arm and extends in a direction downwardly toward a bottom of the anchor,
and

wherein each of the slots slidably receives one of the plurality of fingers during downward insertion of the locking mechanism
through the anchor causing the plurality of arms to splay outwardly to thereby secure the anchor to the plate member,

wherein the plurality of fingers are capable of linearly and non-rotatably sliding in the slot during downward insertion of
the locking mechanism.

US Pat. No. 9,271,768

ORTHOPEDIC FIXATION DEVICES AND INSTRUMENTS FOR INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

1. A spinal system comprising:
a cannulated body comprising a proximal end and a distal end, the distal end comprising two tips extending therefrom and separated
by a longitudinal channel;

a rod reduction collar comprising an inner diameter configured to receive at least a portion of the cannulated body; and
a reducer configured to fit around at least a portion of the cannulated body, proximal to the rod reduction collar
wherein the reducer comprises first and second halves connected by a hinge mechanism
wherein a proximal portion of the reducer comprises first and second longitudinally extending members extending from each
of the first and second halves, and a distal portion of the reducer comprises first and second sleeve members extending from
each of the first and second halves; wherein the reducer engages with the cannulated body proximal to the rod reduction collar.

US Pat. No. 9,623,246

SPINAL CORD STIMULATOR SYSTEM

GLOBUS MEDICAL, INC., Au...

1. A spinal cord stimulation device comprising:
an implantable pulse generator;
a plurality of implantable stimulation electrodes;
a clinician programmer application provided on a computing device;
the implantable pulse generator comprising:
a circuit board comprising a plurality of output capacitors, an application specific integrated circuit and a microcontroller,
the microcontroller in communication with a communication device and with the application specific integrated circuit;

a rechargeable battery;
an antenna; and
wherein the application specific integrated circuit comprising a digital section and an analog section, wherein the digital
section comprises digital elements, timing generators, a plurality of comparators, arbitration control, pulse burst conditioner,
and electrode logic, and wherein the analog section comprises field effect transistors and a plurality of digital-to-analog
convertors,

wherein the arbitration control analyzes the timing generator envelope signals and permits only one signal to be active at
a time.

US Pat. No. 9,510,954

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

Globus Medical, Inc., Au...

1. A method of installing intervertebral implants, the method comprising:
positioning more than one intervertebral implant between adjacent vertebrae, each intervertebral implant having a body portion
with a first end and a second end, the first end being inserted first into the disc space followed by the second end;

rotating an actuation member of at least one of the implants in a first direction to expand the intervertebral implant such
that the implant is implanted at a different height, the rotation of the actuation member causing a translation member of
the implant to move in a first direction, the translation member having at least one expansion portion having two ramped surfaces,
the ramped surfaces abutting and pushing against ramped surfaces on upper and lower endplates of the implant causing the upper
and lower endplates to move in a direction away from the body portion into an expanded position, and

rotating the actuation member of at least one of the implants in a second direction, the rotation of the actuation member
causing the translation member of the implant to move in a second direction, the expansion portion of the translation member
having a pin, a portion of which is located within at least one slot located on one of the first and second endplates, the
movement of the translation member in the second direction causing the pin to ride along the at least one slot thereby moving
the first and second endplates toward the body portion into an unexpanded position.

US Pat. No. 9,452,063

EXPANDABLE FUSION DEVICE AND METHOD OF INSTALLATION THEREOF

GLOBUS MEDICAL, INC., Au...

8. An intervertebral implant comprising:
a first endplate having an upper side and a lower side;
a second endplate having an upper side and a lower side;
a body portion positioned between the first endplate and the second endplate, the body portion having a first end, a second
end, a first side portion connecting the first end and the second end, and a second side portion connecting the first end
and the second end, wherein the first end, second end, first side portion and second side portion define a central opening;

a translation member positioned in the body;
an actuation member received in the body portion, wherein the actuation member includes a distal surface configured to engage
and move the translation member, wherein rotation of the actuation member in a first direction causes movement of the translational
member such that a first planar ramped surface pushes the first endplate to expand the first endplate relative to the second
endplate,

wherein the actuation member comprises a threaded portion and a non-threaded portion, the threaded portion is engaged to the
body portion and the non-threaded portion is engaged to the translation member

wherein the translation member includes a second planar ramped surface, and the first planar ramped surface and the second
planar ramped surface are longitudinally spaced apart on an upper portion of the translation member

wherein the translation member is a single unitary body and includes a central opening that extends from the first endplate
to the second endplate.

US Pat. No. 9,427,260

CLOSED-HEAD POLYAXIAL AND MONAXIAL SCREWS

GLOBUS MEDICAL, INC., Au...

1. A closed-head polyaxial screw comprising:
a set screw;
a bone screw having a head;
a closed head comprising an upper aperture configured to receive the set screw, a lower aperture configured to receive the
bone screw, and an aperture for receiving a rod, wherein the set screw comprises a retaining lip positioned near a bottom
portion of the set screw that prevents the set screw from being removed from the upper aperture as the set screw is moved
upwardly through the closed head;

a first clamp surrounding at least a portion of the head of the bone screw to retain the bone screw in the lower aperture
of the closed head and a second clamp surrounding at least a portion of the head of the bone screw, wherein the first clamp
and the second clamp are configured to be inserted upwardly into the closed head such that the first clamp and the second
clamp come to a stop when the first clamp comes into contact with the second clamp; and

a wedge configured to be seated onto the first clamp and the second clamp, wherein the wedge is spaced from and capable of
moving with respect to the bone screw.

US Pat. No. 9,271,842

EXPANDABLE TRIAL ASSEMBLY FOR EXPANDABLE VERTEBRAL IMPLANT

Globus Medical, Inc., Au...

1. A system for inserting an implant comprising:
a trial assembly configured for insertion between vertebrae in a patient and removal therefrom, wherein the trial assembly
comprises:

a handle portion;
a cylindrical base portion coupled to the handle portion, wherein the cylindrical base portion comprises:
an outer cylinder;
a drive shaft configured to be coaxially received in the outer cylinder, wherein the drive shaft includes a gear at its distal
end, wherein the drive shaft is configured to rotate about a longitudinal axis of the cylindrical base portion; and

a scale configured to threadingly receive the drive shaft within the scale; and
a tip assembly configured to expand, wherein the tip assembly comprises:
an outer member;
an upper gear member configured to engage the gear on the drive shaft and engage the outer member;
an inner member configured to be coaxially received within the outer member; and
a lower gear member configured to engage the gear on the drive shaft and engage the inner member,
wherein the scale is configured to measure expansion of the tip assembly and
wherein the upper gear member and the lower gear member are capable of moving with respect to each other;
an expandable implant configured for insertion into a patient's spine, the expandable implant having a longitudinal axis and
comprising a gear member configured to expand the expandable implant; and

the expandable implant configured to be inserted between the vertebrae in the patient and expanded, wherein the scale on the
trial assembly provides a measurement of expansion of the tip assembly to give a measurement for a height of expansion of
the expandable implant; and

an inserter tool comprising: an inserter tip assembly having a base portion and a central shaft disposed in a through-bore
in the base portion, wherein the central shaft is configured to engage the expandable implant, arms for engaging slots of
the expandable implant and an implant engagement gear for engaging the gear member of the expandable implant,

a primary gear mechanism configured to transfer rotation of a primary drive shaft to the expandable implant to cause expansion
of the expandable implant; and

a secondary gear mechanism configured to transfer rotation of a secondary drive shaft to the central shaft,
wherein the inserter tool is configured to cause the tip assembly of the inserter tool to angulate.

US Pat. No. 9,226,785

LOCKING BONE SCREWS AND METHODS OF USE THEREOF

Globus Medical, Inc., Au...

1. A bone plate and screw system comprising:
a screw head and a thread shaft, the screw head having a plurality of fingers separated by grooves, the fingers forming an
inner bore;

a bone plate having at least one hole for receiving the screw head; and
a locking insert received in the inner bore of the screw head, the locking insert capable of rotating in the inner bore of
the screw head,

wherein the screw head is substantially spherical and the finger elements are capable of deflecting in and out,
wherein the hole is spherical and substantially approximates the screw head in shape such that the screw can be placed into
a bone plate to provide screw angulation; and

wherein the locking insert comprises a shaft having an upper end and lower end, the upper end comprises a plurality of radially
extending arms that in a first position are located in the grooves and in a second position mate with the finger elements.

US Pat. No. 9,687,255

DEVICE AND METHODS FOR FRACTURE REDUCTION

GLOBUS MEDICAL, INC., Au...

1. A method of forming a curvilinear void in bony structure, the method comprising the steps of:
accessing a bony structure with a cannula;
inserting a distal portion of a curvilinear drilling device through the cannula and into the bony structure, wherein the drilling
device comprises a flexible drill shaft assembly including a sharp cutting tip, a flexible rotatable drive shaft coupled to
the tip, and a flexible, moveable and non-rotatable housing;

manipulating the distal portion of the curvilinear drilling device to create a curvilinear void in the bony structure;
enlarging the void by expansion of an expandable element mounted on the distal portion of the curvilinear drilling device;
and

collapsing the expandable element and removing the drilling device from the cannula.

US Pat. No. 9,585,765

DEVICES AND METHODS FOR CORRECTING VERTEBRAL MISALIGNMENT

GLOBUS MEDICAL, INC, Aud...

1. A method of correcting vertebral misalignment, the method comprising:
positioning an implant within a space between two adjacent vertebral bodies, wherein the implant comprises:
a frame assembly include a left lateral portion, a central portion, and a right lateral portion, wherein the left and right
lateral portions define enlarged heads configured to receive fasteners therein for securing the frame assembly to a first
vertebral body, and wherein the central portion defines a lumen therethrough;

a reducing member configured to be slidably received in the lumen of the central portion, wherein the reducing member includes
an anterior portion and a plurality of extensions extending posteriorly therefrom, wherein the plurality of extensions define
a channel therebetween, wherein the channel is configured to receive a portion of the central portion; and

an actuator positioned within the reducing member and extending into an actuator receiving portion of the frame assembly,
and configured to control a position of the reducing member relative to the frame assembly;

securing the frame assembly to a first vertebral body of the two adjacent vertebral bodies;
securing the reducing member to a second vertebral body of the two adjacent vertebral bodies, wherein the second vertebral
body is disposed superiorly of the first vertebral body;

rotating the actuator to move the second vertebral body relative to the first vertebral body; and
securing the reducing member relative to the frame assembly.
US Pat. No. 9,463,264

BONE GRAFTS AND METHODS OF MAKING AND USING BONE GRAFTS

Globus Medical, Inc., Au...

1. A method of making a bone graft, the method comprising:
mixing 20% to 95% by weight collagen type I with at least one mineral to form a mixture;
refrigerating the mixture for 30 minutes to 5 hours to form a cooled mixture;
neutralizing the cooled mixture to a pH between 6.5 and 8.5 to form a neutralized mixture;
refrigerating the neutralized mixture for 1 hour to 24 hours to form a cooled, neutralized mixture;
blast chilling the cooled, neutralized mixture at a temperature below ?20° C. for 1 hour up to 24 hours to form a blast chilled
mixture;

freeze drying the blast chilled mixture for 24 to 72 hours to form a dried pad mixture;
physically or chemically cross-linking the dried pad mixture to form a cross-linked mixture; and
freeze drying the cross-linked mixture to obtain the bone graft,
the bone graft comprising 20% to 95% by weight with respect to total weight of the bone graft, of the collagen type I, and
20% to 95% by weight with respect to the total weight of the bone graft, of the at least one mineral, wherein the at least
one mineral has two or more different dissolution rates, thereby allowing the bone graft to enhance bone healing in both early
and late phases of the bone healing.

US Pat. No. 9,452,060

SIX DEGREE SPINE STABILIZATION DEVICES AND METHODS

Globus Medical, Inc., Au...

1. An implant for stabilizing first and second adjacent bones in a patient, comprising:
a first support component having a first side adapted to be affixed to the first bone of the patient, and a second side opposite
the first side having a smooth surface;

a resilient core having a third side having a smooth surface and positionable in mating slidable engagement with the second
side, said resilient core further including a fourth side opposite the third side;

a second support component having a fifth side mateable with the fourth side, and a sixth side opposite the fifth side adapted
to be affixed to the second bone of the patient;

whereby an axis of the implant is defined as extending through said implant from the first adjacent bone to the second adjacent
bone;

wherein said core is positionable between said first and second support components to thereby be positionable between the
first and second adjacent bones;

wherein said core separates at least a portion of each of said first and second supports at a relative first distance along
said axis, said core being resiliently deformable under pressure to separate said at least a portion each of said first and
second supports at a second, lesser relative distance along said axis;

wherein said core may slide upon said third side, in engagement with said second side, in a radial direction with respect
to said axis;

wherein said core includes an inflection region having a narrower width than adjacent flanking segments to accommodate flexion
of the core;

wherein said core has a central horizontal axis and includes a hollow interior that is asymmetric about said horizontal axis;
wherein at least one projection extends from the second side of the first support component and into the hollow interior of
the core to limit an extent of movement of the first support component with respect to the core; and

wherein at least one pin is positioned substantially transverse to the axis of the implant to connect the second support component
to the core,

wherein when said first support component is affixed to the first adjacent bone, and said second support component is affixed
to the second adjacent bone, and said core is positioned between said first and second support components, the first and second
adjacent bones are stabilized, and said core may both resiliently deform and slide separately or simultaneously, to enable
a kinematic movement of the two adjacent bones similar to a natural kinematic movement of the bones, and

wherein the first side is configured with a first aperture and the sixth side is configured with a second aperture, the first
and second apertures are configured to receive fasteners to secure the implant to the first and second adjacent bone.

US Pat. No. 9,393,062

DEVICES FOR DELIVERING BONE FILLER MATERIAL AND ASSOCIATED METHODS OF USE

Globus Medical, Inc., Au...

1. A device for delivering a bone filler material comprising:
a housing including a body having a throughbore and an upper chamber that intersects the throughbore;
a plunger comprising a shaft having external threads, wherein the plunger is configured for advancement through the throughbore
of the housing;

a receiving member disposed in the upper chamber and configured to releasably engage the plunger; and
an actuator rod assembly including an actuator rod and an actuator spring, the actuator rod extending from the upper chamber
and the actuator spring disposed over the actuator rod which is configured to engage the receiving member,

wherein the receiving member is configured to translate within the upper chamber from an engaged position where the receiving
member engages the plunger to a disengaged position where the receiving member is not engaged with the plunger.

US Pat. No. 9,237,957

LOW PROFILE PLATE

GLOBUS MEDICAL, INC., Au...

1. A spinal system comprising:
a spacer for inserting into an intervertebral space, the spacer including:
an upper surface,
a lower surface,
an opening that extends between the upper surface to the lower surface, wherein the spacer is formed of a first member operably
coupled to a second member,

a first arm, and
a second arm, wherein an upper chamfer is formed on a distal most end of the first arm and a lower chamfer is formed on a
distal most end of the second arm; and

a plate for abutting the spacer, the plate including:
a plate body,
a first opening formed in the plate body for receiving a first bone screw, wherein the first opening is angled in an upward
direction;

a second opening formed in the plate body for receiving a second bone screw, wherein the second opening is angled in a downward
direction;

a set screw for preventing back-out of both the first and the second bone screws, wherein the set screw has a first position
whereby the first and second bone screws can be inserted past the set screw and into the first and second openings and a second
position following rotation of the set screw whereby the first and second bone screws are prevented from backing out by the
set screw, and

a pair of extensions that extend from the plate body, wherein the extensions are configured to extend around and engage outer
sidewalls of the first and second arms, wherein a first extension of the pair of extensions includes a first enclosed window
and a second extension of the pair of extensions includes a second enclosed window, wherein the first enclosed window receives
a first notch that extends laterally outward from the outer sidewall of the first arm and the second enclosed window receives
a second notch that extends laterally outward from the outer sidewall of the second arm.

US Pat. No. 9,687,279

FACET JOINT REPLACEMENT INSTRUMENTS AND METHODS

Globus Medical, Inc., Au...

1. A facet joint replacement device, said device comprising:
a superior facet joint replacement component configured to replace a natural superior articular facet on a first vertebra
of a spine;

an inferior facet joint replacement component, said inferior facet joint replacement component comprising a first coupling
portion configured to engage a complementary first coupling portion of the superior component to couple the inferior component
to the superior component in a predetermined orientation, wherein the first coupling portion of the inferior component comprises
a clip having a pair of pins separated from a pair of prongs,

wherein the pair of pins are shaped to engage the superior facet joint replacement component and the pair of prongs are shaped
to engage the inferior facet joint replacement component, and

wherein the pair of pins are cylindrical and have a constant diameter over their entire length and the pair of prongs are
configured as flanges, correspond to a gripping feature on the inferior facet joint replacement component, and are separated
by a slot substantially centered between the pair of prongs to enable the pair of prongs to independently move with respect
to each other.

US Pat. No. 9,539,029

EXTERNAL FIXATOR ASSEMBLY

GLOBUS MEDICAL, INC., Au...

1. An external fixator assembly comprising:
a first shaft having a first coupling end and a first free end;
a second shaft having a second coupling end and a second free end;
a coupling pivotally retaining the first coupling end and the second coupling end;
a first clamp assembly disposed on the first shaft between the coupling and the first free end, the first clamp assembly comprising:
a first inner clamp member disposed proximate to the coupling, the first inner clamp member having a first inner slot;
a first outer clamp member disposed proximate to the first free end, the first outer clamp member having a first outer slot;
and

a first biasing member disposed in the first inner slot and the first outer slot such that first biasing member biases the
first inner clamp member toward the first outer clamp member; and

a second clamp assembly disposed on the second shaft between the coupling and the second free end, the second clamp assembly
comprising:

a second inner clamp member disposed proximate to the coupling, the second in the clamp member having a second inner slot;
a second outer clamp disposed proximate to the second free end, the second outer clamp member having a second outer slot;
and

a second biasing member disposed in the second inner slot and the second outer slot such that the second biasing member biases
the second inner clamp member toward the second outer clamp member.

US Pat. No. 9,480,573

EXPANDABLE INTERBODY SPACER

Globus Medical, Inc., Au...

1. A surgical method comprising:
inserting in a disc space an expandable spacer, wherein the expandable spacer has a first unexpanded configuration and a second
expanded configuration that is larger than the first unexpanded configuration, wherein the expandable spacer comprises:

an upper endplate and a lower endplate, wherein the upper endplate comprises a first endplate portion and a second endplate
portion;

a translation member and an actuation member, wherein the actuation member is operably coupled to the translation member;
and

at least one side slot, wherein the at least one side slot extends a majority of the length of the translation member; and
rotating the actuation member in a first direction to cause lateral translation of the translation member in the first direction
to thereby cause sliding engagement between ramps of the translation member and ramps of inner sidewalls of the upper and
lower endplates thereby causing outward expansion of the upper and lower endplates,

wherein an installation instrument engages with the at least one side slot,
wherein in the first unexpanded configuration, the first endplate portion and the second endplate portion align with one another
such that no opening extends through a midline of the expandable spacer and the first endplate portion and second endplate
portion are in contact with the actuation member, and in the second expanded configuration, the first endplate portion and
the second endplate portion spread away from one another such that an opening extends through the midline of the expandable
spacer and the first endplate portion and second endplate portion are no longer in contact with the actuation member, and

wherein the upper endplate and the lower endplate are hinged in the first unexpanded configuration and the second expanded
configuration.