US Pat. No. 9,296,159

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens, comprising:
a polymeric lens body that is the reaction product of a polymerizable composition, said polymerizable composition comprising
(a) at least one siloxane monomer; and
(b) ethylene glycol methyl ether methacrylate (EGMA) in an amount of from 1 to 20 unit parts by weight;
wherein the polymerizable composition further comprises methyl methacrylate (MMA), and a ratio of unit parts by weight of
MMA to unit parts by weight of EGMA present in the polymerizable composition is from about 6:1 to about 1:1.

US Pat. No. 9,296,160

METHOD FOR MOVING WET OPHTHALMIC LENSES DURING THEIR MANUFACTURE

CooperVision Internationa...

1. A method of manufacturing an ophthalmic lens, comprising:
providing an ophthalmic lens in a volume of liquid in a well of a lens carrier so that the ophthalmic lens is understood to
be a wet lens;

removing the wet lens from the well using a wet lens pick up head comprising an outer periphery sized and convexly shaped
to form a fit with a posterior concave surface of the wet lens;

moving the wet lens pick up head with the posterior surface of the wet lens fixed to the outer periphery of the wet lens pick
up head toward a blister package having a cavity to receive the wet lens; and

releasing the wet lens from the wet lens pick up head into the cavity of the blister package,
wherein, during the moving, the wet lens is fixed to a first set of holes in the outer periphery of the wet lens pick up head
and is retained by vacuum, and excess liquid is removed from the wet lens by a second set of holes recessed from the periphery
of the wet lens pick up head that do not come in contact with the wet lens surface.

US Pat. No. 9,140,908

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens comprising:
a polymeric lens body that is a reaction product of a polymerizable composition comprising
a) at least one hydrophilic vinyl amide-containing monomer;
b) at least one acrylate-containing siloxane monomer; and
c) at least one vinyl ether-containing monomer, with the proviso that the at least one acrylate-containing siloxane monomer
does not comprise a siloxane monomer represented by formula (III),

where n is an integer from about 10 to 15.
US Pat. No. 9,248,928

METHODS OF MANUFACTURING CONTACT LENSES FOR DELIVERY OF BENEFICIAL AGENTS

CooperVision Internationa...

1. A method of manufacturing a contact lens, said method comprising:
a) polymerizing a monomer mixture comprising at least one carboxylic-acid containing monomer to form a lens-shaped polymerization
product comprising carboxylic acid groups;

b) placing the lens-shaped polymerization product in a package containing a packaging solution comprising a buffer and a beneficial
cationic agent, wherein said packaging solution has an osmolality of about 200 to about 400 mOsm/kg, and wherein said packaging
solution i) has an ionic strength of less than about 0.1, or ii) is temperature-sensitive, or iii) has an ionic strength of
less than about 0.1 and is temperature-sensitive; and

c) sealing and autoclaving the package to provide a sterile packaged contact lens, wherein the beneficial cationic agent ionically
binds to the carboxylic acid groups and releases from the contact lens in an in vitro release assay;

wherein at least 50% more of the cationic agent is taken up by the lens compared to an identical contact lens packaged in
PBS.

US Pat. No. 9,261,712

CONTACT LENSES, APPARATUS AND METHODS

COOPERVISION INTERNATIONA...

1. A method useful in manufacturing a contact lens, the method comprising:
dispensing a sufficient amount of a liquid composition onto a contact lens mold section having a lens defining surface and
a flange region to provide a coating of the liquid composition on at least a substantial portion of the lens defining surface
of the contact lens mold section;

wherein the dispensing employs a pneumatically operated valve to dispense the sufficient amount of the liquid composition
as a plurality of separate portions of the liquid composition onto the lens defining surface of the contact lens mold section
while reducing the amount of the liquid composition dispensed onto the flange region of the contact lens mold section, and
each of the separate portions of the liquid composition has a volume which is less than about 1000 nanoliters and which differs
by less than 5% from an average volume of the plurality of separate portions of the liquid composition.

US Pat. No. 9,217,813

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens comprising:
a polymeric lens body that is a reaction product of a polymerizable composition comprising
a) at least one acrylate-containing siloxane monomer represented by formula (I):

where m is an integer from 3 to 10, n is an integer from 0 to 10, R1 is an alkyl group having 1 to 4 carbon atoms, R2 is hydrogen or a methyl group, and R3 is hydrogen or a methyl group;

b) at least one hydrophilic vinyl-containing monomer; and
c) at least one vinyl-containing cross-linking agent,
wherein the contact lens has an ionoflux of less than 10×10?3 mm2/min; and

wherein the polymerizable composition has a molar ratio of total amount of hydrophilic vinyl-containing monomer to total amount
of acrylate-containing siloxane monomer of from 5:1 to 30:1, respectively.

US Pat. No. 9,164,298

WETTABLE SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens comprising:
a polymeric lens body that is the reaction product of a polymerizable composition comprising:
a) at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 1000;
b) at least one bi-functional acrylate-containing siloxane monomer represented by formula (II),

 wherein R1 of formula (II) is selected from either hydrogen or a methyl group, R2 of formula (II) is selected from either hydrogen or a C1-4 hydrocarbon group, m of formula (II) represents an integer of from 0 to 10; n of formula (II) represents an integer of from
4 to 100, and a and b represent integers of 1 or more;

c) at least one hydrophilic vinyl-containing monomer; and
d) at least one vinyl-containing cross-linking agent,
wherein the polymerizable composition has a molar ratio of total amount of hydrophilic vinyl-containing monomer to total amount
of acrylate-containing siloxane monomer of from 5:1 to 30:1, respectively and

wherein the polymerizable composition has a molar ratio of total amount of polymerizable vinyl groups from the total amount
of hydrophilic vinyl-containing monomer to total amount of polymerizable vinyl groups from the total amount of vinyl-containing
cross-linking agents of from 100:1 to 1000:1, respectively.

US Pat. No. 9,161,598

OPHTHALMIC DEVICES FOR DELIVERY OF BENEFICIAL AGENTS

CooperVision Internationa...

1. An unworn contact lens immersed in a packaging solution and sealed in a package, said contact lens comprising:
(a) a hydrogel comprising integral phosphorylcholine groups; and
(b) a releasable ionic agent electrostatically bound to the phosphorylcholine groups, wherein the ionic agent is polyionic
or comprises at least one guanidinium group or is both polyionic and comprises at least one guanidinium group.

US Pat. No. 9,156,214

POLAR THERMOPLASTIC OPHTHALMIC LENS MOLDS, OPHTHALMIC LENSES MOLDED THEREIN, AND RELATED METHODS

CooperVision Internationa...

1. A method of manufacturing a silicone hydrogel contact lens body, comprising:
providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured
to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to
mold a posterior surface of a contact lens, the molding surface of at least one of the first mold member and the second mold
member comprising at least one polar thermoplastic polymer with an average polarity of from 1% to 7%, the first mold member
and the second mold member being configured to form a lens-shaped cavity therebetween when combined as a mold assembly;

placing a polymerizable composition comprising a) at least one silicone monomer, silicone macromer, silicone prepolymer, or
combination thereof, and b) at least one hydrophilic monomer in the first mold member;

assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped
cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly;

curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the lens-shaped
cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body;

wherein the lens body has ophthalmically acceptably wettable anterior and posterior surfaces without application of a surface
treatment to the lens body, or without the presence of an interpenetrating network (IPN) of a polymeric wetting agent in the
lens body.

US Pat. No. 9,360,594

HIGH WATER CONTENT SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens, comprising:
a polymeric lens body that is the reaction product of a polymerizable composition free of organic diluent, said polymerizable
composition comprising

(a) a first siloxane monomer represented by formula (1):

wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group;

(b) a second siloxane monomer having a number average molecular weight of at least 7,000 daltons; and
(c) at least one vinyl-containing cross-linking agent;
wherein the contact lens has an equilibrium water content (EWC) from about 30% to about 70% when fully hydrated,
wherein the second siloxane monomer having a number average molecular weight of at least 7,000 daltons is a second siloxane
monomer represented by formula (2):


wherein each R1 of formula (2) is independently selected from either a hydrogen atom or a methyl group; R2 of formula (2) is selected from either of a hydrogen atom or a hydrocarbon group having 1 to 4 carbon atoms; m of formula
(2) represents an integer of from 0 to 10; n of formula (2) represents an integer of from 4 to 100; a and b represent integers
of 1 or more; a+b is equal to 20-500; b/(a+b) is equal to 0.01-0.22; and the configuration of siloxane units includes a random
configuration.

US Pat. No. 9,322,959

CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS

CooperVision Internationa...

1. An optically clear silicone hydrogel contact lens comprising:
a polymeric lens body that is the reaction product of a polymerizable composition comprising:
a) at least 25 wt. % of at least one hydroxyalkyl methacrylate; and
b) at least 20 wt. % of at least one HEMA-compatible bifunctional polysiloxane comprising at least 6 siloxane groups,
wherein the HEMA-compatible bifunctional polysiloxane has an HLB value of at least 7,
wherein the wt. % of the hydroxyalkyl methacrylate and the HEMA-compatible bifunctional polysiloxane is based on the total
weight of polymerizable monomers in the composition.

US Pat. No. 9,625,616

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A method of manufacturing a silicone hydrogel contact lens comprising:
curing a polymerizable composition comprising a siloxane monomer and a hydrophilic monomer to form a cured silicone hydrogel
contact lens;

hydrating the cured silicone hydrogel contact lens;
extracting the hydrated silicone hydrogel contact lens with an extraction liquid comprising an aqueous solution of a single
organic solvent selected from ethyl lactate, or ethylene carbonate, or propylene carbonate, or propylene glycol, or butanediol,
to make an extracted silicone hydrogel contact lens;

removing organic solvent from the extracted silicone hydrogel contact lens to make an ophthalmically-acceptable lens; and
packaging the ophthalmically-acceptable lens,
wherein:
the extraction liquid and any other liquid used for processing the cured or hydrated silicone hydrogel contact lens has a
flash point of at least 50° C.; and

the hydrated silicone hydrogel contact lens has surface distortions that are reduced after the extraction and/or removing
step.

US Pat. No. 9,272,473

WETTABLE SILICONE HYDROGEL CONTACT LENSES AND RELATED COMPOSITIONS AND METHODS

CooperVision Internationa...

1. A method for producing a silicone hydrogel contact lens, comprising:
providing a polymerizable silicone hydrogel lens precursor composition in a contact lens shaped cavity of a non-polar resin
contact lens mold, the polymerizable silicone hydrogel precursor composition comprising a silicone-containing component and
a non-silicone containing component, the non-silicone containing component being present in an amount between about 10% to
about 60% (w/w) based upon the weight of all reactive components of the precursor composition and said non-silicone containing
component comprising an N-vinyl pyrrolidone (NVP) monomer and a N,N-dimethylacrylamide (DMA) monomer, and the contact lens
mold comprising a first contact lens mold member and a second contact lens mold member;

polymerizing the polymerizable silicone hydrogel lens precursor composition in the non-polar resin contact lens mold using
heat or ultraviolet light to form a pre-extracted polymerized silicone hydrogel contact lens product having a dry weight,
the pre-extracted silicone hydrogel contact lens product having a removable monomeric component in an amount of at least 10%
(w/w) based on the dry weight of the pre-extracted polymerized silicone hydrogel contact lens product;

extracting and hydrating the pre-extracted polymerized silicone hydrogel contact lens product by contacting the pre-extracted
polymerized silicone hydrogel contact lens product with an extraction media to produce a silicone hydrogel contact lens having
a dry weight no greater than 90% of the dry weight of the pre-extracted polymerized silicone hydrogel contact lens product;
and

packaging the silicone hydrogel contact lens in a contact lens package,
wherein the silicone hydrogel contact lens has an advancing contact angle less than about 120 degrees, a tensile modulus less
than about 1.6 MPa, an oxygen permeability of at least about 70 barrers, and a water content of at least about 30% by weight.

US Pat. No. 9,492,951

OPHTHALMIC DEVICE MOLDS FORMED FROM WATER-SOLUBLE VINYL ALCOHOL COPOLYMER, OPHTHALMIC DEVICES MOLDED THEREIN, AND RELATED METHODS

CooperVision Internationa...

1. A method of manufacturing an ophthalmic device, comprising:
(a) providing at least one unmodified water-soluble vinyl alcohol copolymer and wherein the at least one unmodified water-soluble
vinyl alcohol copolymer is a vinyl alcohol copolymer essentially free of ethylene units;

(b) using the at least one unmodified water-soluble vinyl alcohol copolymer to form at least one of a first mold member and
a second mold member, the first mold member comprising a molding surface configured to mold an anterior surface of the ophthalmic
device and the second mold member comprising a molding surface configured to mold a posterior surface of an ophthalmic device,
the first mold member and the second mold member configured to form an ophthalmic device-shaped cavity therebetween when combined
as a mold assembly;

(c) placing a polymerizable composition comprising at least one hydrophilic monomer in the first mold member or the second
mold member;

(d) assembling the mold assembly by contacting the first mold member and the second mold member so as to form the ophthalmic
device-shaped cavity therebetween with the polymerizable composition contained in the ophthalmic device-shaped cavity of the
mold assembly; and

(e) curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the ophthalmic
device-shaped cavity of the mold assembly, the polymerized reaction product comprising a polymeric ophthalmic device body.

US Pat. No. 9,370,906

METHODS, DEVICES, AND SYSTEMS FOR INJECTION MOLDING CONTACT LENSES

CooperVision Internationa...

1. A method of manufacturing a contact lens, comprising:
providing a first mold insert comprising a body section; said first mold insert comprising a lens forming surface including
a raised non-uniform region having an opening formed through the lens forming surface in the location of the raised non-uniform
region, and a fluid channel passing through the body section and in fluid communication with the opening;

placing the first mold insert into a mold block so that the lens forming surface of the first mold insert and the raised non-uniform
region form part of a lens-shaped cavity;

providing a lens forming composition through the fluid channel and the opening so that an amount of the lens forming composition
is deposited in the lens-shaped cavity;

allowing the lens forming composition to form a contact lens body retaining the shape of the lens-shaped cavity;
removing the contact lens body from the mold block and the mold insert;
washing the contact lens body;
inspecting the contact lens body;
placing the contact lens body in a package with a packaging solution;
sealing the package containing the contact lens body and the packaging solution; and
sterilizing the package containing the contact lens body and the packaging solution to produce a finished contact lens.

US Pat. No. 9,193,118

OPHTHALMIC LENS MOLDS, OPHTHALMIC LENSES MOLDED THEREIN, AND RELATED METHODS

CooperVision Internationa...

1. A method of manufacturing a silicone hydrogel contact lens body, comprising:
providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured
to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to
mold a posterior surface of a contact lens, the first mold member and the second mold member being configured to form a lens-shaped
cavity therebetween when combined as a mold assembly, the molding surface of at least one of the first mold member and the
second mold member comprising a thermoplastic polymer, the molding surface having a percent polarity from 3% to 20% and a
surface energy from about 25 mN/m to about 40 mN/m;

placing a polymerizable composition comprising a) at least one silicon-containing monomer and b) at least one hydrophilic
monomer in the first mold member, the polymerizable composition having a surface tension from about 20 mN/m to about 25 mN/m,
and a surface energy differential of the surface tension of the polymerizable composition less the surface energy of the molding
surface is less than or equal to zero (0);

assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped
cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; and

curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the lens-shaped
cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body.

US Pat. No. 9,322,958

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens comprising:
a polymeric lens body that is free of a polyvinylpyrrolidone-containing interpenetrating network, said contact lens having
a water content of at least 30% by weight, an oxygen permeability of at least 120 barrers, a contact angle hysteresis of less
than 15° , and a modulus of less than about 0.8 MPa, wherein the contact angle hysteresis is the difference between an advancing
contact angle of the silicone hydrogel contact lens and a receding contact angle of the silicone hydrogel contact lens.

US Pat. No. 9,102,110

SYSTEMS AND METHODS FOR REMOVING LENSES FROM LENS MOLDS

CooperVision Internationa...

1. A method of producing a silicone hydrogel contact lens, comprising:
providing a contact lens mold assembly comprising a first mold section fused to a second mold section, wherein said first
and second mold sections comprise an ethylene vinyl alcohol resin, and a polymerized silicone hydrogel lens shaped article
disposed between the first mold section and the second mold section;

immersing the contact lens mold assembly in an immersion liquid having a temperature of between about 20° C. to about 95°
C. for a period of time sufficient to initiate separation of the mold sections;

removing the contact lens mold assembly comprising the first mold section fused to the second mold section from the immersion
liquid;

separating the fused first and second mold sections after the immersing step using one or more wedge-shaped elements to pry
apart and separate the fused first and second mold sections so that the lens shaped article is adhered to a lens defining
surface of one of the separated mold sections; thereafter

contacting the mold section and the polymerized silicone hydrogel lens shaped article adhered thereto with a heated soaking
liquid to release the lens shaped article from the lens defining surface of the mold section; and

removing the released lens shaped article from the mold section, wherein the contact lens mold assembly is immersed in the
immersion liquid for about 1 second to about 10 seconds.

US Pat. No. 9,457,522

METHODS AND APPARATUS USEFUL IN MANUFACTURING LENSES

COOPERVISION INTERNATIONA...

1. A method of manufacturing a contact lens comprising:
providing a polymerized contact lens product on a single mold section, the single mold section comprising a mandrel engagement
surface;

placing the single mold section in contact with an adjustable mandrel, the adjustable mandrel comprising a plurality of pivotable
clutches and a mold section engagement member;

adjusting the positions of the plurality of pivotable clutches, thereby adjusting the diameter of the mold section engagement
member of the mandrel such that the mandrel engagement surface of the single mold section and the mold section engagement
member of the adjustable mandrel interact to fixedly retain the single mold section on the adjustable mandrel; and

delensing the contact lens product from the single mold section to separate the contact lens product from the single mold
section.

US Pat. No. 9,278,489

OPHTHALMIC DEVICE MOLDS AND RELATED METHODS

CooperVision Internationa...

1. A method of manufacturing an ophthalmic device, comprising:
(a) placing a polymerizable composition comprising at least one hydrophilic monomer in direct contact with an entire molding
surface configured to cast mold an anterior or posterior surface of an ophthalmic device; and

(b) curing the polymerizable composition in direct contact with the entire molding surface to form a polymerized reaction
product comprising a polymeric ophthalmic device body,
wherein a first polymer is used to form a first portion of said molding surface configured to mold the entire anterior or
posterior surface of an ophthalmic device, a second polymer is used to form a distinct second portion of said molding surface
configured to mold the entire anterior or posterior surface of an ophthalmic device and, when combined, the distinct first
and second portions form the entire said molding surface configured to mold the entire anterior or posterior surface of an
ophthalmic device; wherein the first polymer comprises at least one vinyl alcohol copolymer which is not an ethylene-vinyl
alcohol copolymer and wherein the second polymer comprises polypropylene.

US Pat. No. 9,839,271

CONTACT LENS CASE AND RELATED METHODS AND KITS

CooperVision Internationa...

1. A case for holding one or more contact lenses, the case configured to receive an inner pod, wherein
the case comprises an upper part and a lower part, the upper part structured to move relative to the lower part from an open
configuration wherein the upper and lower parts are at least partially separated to a closed configuration wherein the upper
and lower parts are together, and

the upper part structured to move relative to the lower part from a disengaged position to an engaged position wherein, in
the disengaged position, the case is movable between the open and closed configurations and in the engaged position, the case
is locked in the closed configuration wherein the upper part comprises a cover mounted on a compression member, the cover
mounted for movement such that the cover rotates with respect to the compression member, and the upper part includes an annulus,
the annulus positioned between the cover and the compression member, arranged to apply pressure to the compression member
when the case is in the engaged position.

US Pat. No. 9,664,925

OPHTHALMIC DEVICE MOLDS FORMED FROM HIGHLY AMORPHOUS VINYL ALCOHOL POLYMER, OPHTHALMIC DEVICES MOLDED THEREIN, AND RELATED METHODS

Coopervision Internationa...

1. A method of manufacturing an ophthalmic device, comprising:
(a) providing at least one highly amorphous vinyl alcohol polymer having an average level of crystallinity of less than 25%;
(b) using the at least one vinyl alcohol polymer to form at least one of a first mold member and a second mold member, the
first mold member comprising a molding surface configured to mold an anterior surface of an ophthalmic device and the second
mold member comprising a molding surface configured to mold a posterior surface of an ophthalmic device, the first mold member
and the second mold member configured to form an ophthalmic device-shaped cavity therebetween when combined as a mold assembly;

(c) placing a polymerizable composition comprising at least one hydrophilic monomer in the first mold member or the second
mold member;

(d) assembling the mold assembly by contacting the first mold member and the second mold member so as to form the ophthalmic
device-shaped cavity therebetween with the polymerizable composition contained in the ophthalmic device-shaped cavity of the
mold assembly; and

(e) curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the ophthalmic
device-shaped cavity of the mold assembly, the polymerized reaction product comprising a polymeric ophthalmic device body.

US Pat. No. 9,498,035

SILICONE HYDROGEL CONTACT LENSES FOR SUSTAINED RELEASE OF BENEFICIAL POLYMERS

CooperVision Internationa...

1. An unworn silicone hydrogel contact lens immersed in a packaging solution and sealed in a package, said contact lens comprising:
a) a hydrated polymerization product of a monomer mixture comprising at least one silicone monomer and at least one anionic
monomer in an amount to provide the polymerization product with an ionic content of about 0.6% to about 2.2%; and

b) a cationic polymer having a molecular weight of about 1,500 to 30,000 electrostatically attached to the hydrated polymerization
product, wherein the contact lens sustains release of the cationic polymer for at least 6 hours.

US Pat. No. 10,029,432

METHODS FOR MAKING OPHTHALMIC LENSES WITH AN AXIS POSITIONING SYSTEM

COOPERVISION INTERNATIONA...

1. A method for producing an ophthalmic lens, comprising:providing a plastic mold section having a lens button with a posterior surface comprising a toric zone with a major axis;
mounting the plastic mold section onto a mandrel, said mandrel having a flywheel, a base unit, and a projection having a rotational axis that is offset from a rotational axis of a lathe assembly;
fixing the flywheel to a first reference point with an aligner so that the first reference point is at a first radian position;
rotating the base unit relative to the flywheel so that a second reference point is at a second radian position; and
using vacuum to fix the flywheel and the base unit from rotating relative to one another.

US Pat. No. 9,616,626

OPHTHALMIC DEVICE MOLDS FORMED FROM VINYL ALCOHOL COPOLYMER, OPHTHALMIC DEVICES MOLDED THEREIN, AND RELATED METHODS

CooperVision Internationa...

1. A method of manufacturing an ophthalmic device, comprising:
(a) providing at least one vinyl alcohol copolymer,
(b) using the at least one vinyl alcohol copolymer to form at least one of a first mold member and a second mold member, the
at least one of the first mold member and the second mold member comprising a device-forming molding surface having a static
sessile drop contact angle less than 50 degrees and which is free of a plasma treatment, wherein the first mold member comprises
a molding surface configured to mold an anterior surface of an ophthalmic device and the second mold member comprises a molding
surface configured to mold a posterior surface of an ophthalmic device, and the first mold member and the second mold member
are configured to form an ophthalmic device-shaped cavity therebetween when combined as a mold assembly;

(c) placing a polymerizable composition comprising at least one hydrophilic monomer in the first mold member or the second
mold member;

(d) assembling the mold assembly by contacting the first mold member and the second mold member so as to form the ophthalmic
device-shaped cavity therebetween with the polymerizable composition contained in the ophthalmic device-shaped cavity of the
mold assembly; and

(e) curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the ophthalmic
device-shaped cavity of the mold assembly, the polymerized reaction product comprising a polymeric ophthalmic device body.

US Pat. No. 9,574,038

CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS

CooperVision Internationa...

1. An optically clear silicone hydrogel contact lens comprising:
a hydrated polymeric lens body that is the reaction product of a polymerizable composition comprising:
a) at least 25 wt. % of at least one hydroxyalkyl methacrylate; and
b) at least 20 wt. % of at least one HEMA-compatible polysiloxane represented by Formula (I):

wherein R1 and R2 are independently selected from either hydrogen or a methyl group, X is CH2CH2O or CH2CH(OH)CH2O, k is an integer of 0 or 1, Z is a C2-C10 alkylene, m is an integer of 0 to 160, n is an integer of 1 to 75, p is an integer of 0 to 40, q is an integer of 0 to 20,
h is an integer of 1 to 75, j is an integer of 0 or 1, A is 0 or CH2, i is an integer of 0 or 1, D is a C2-C6 alkylene optionally substituted with one or more groups selected from hydroxyl, methoxy, methyl, and ethyl, L is either methyl
or a side chain that is the same as an opposite side chain on the same silicon atom as L, Q is either methyl or a side chain
that is the same as an opposite side chain on the same silicon atom as Q, where the sum of m, n, and h is at least 5,

wherein the HEMA-compatible polysiloxane has an HLB value of at least 5, or has a hydroxyl group content of at least 1 wt.
% based on the average molecular weight of the polysiloxane, or has both an HLB value of at least 5 and has a hydroxyl group
content of at least 1 wt. %,

wherein the wt. % of the hydroxyalkyl methacrylate and the HEMA-compatible polysiloxane is based on the total weight of polymerizable
monomers in the composition, and

wherein when Z is a C3 alkylene, and when i and j are 0, then R1 is methyl and/or the at least one of p and q is at least 1, and when j is 1 and A is 0, then i is 1 and R1 is methyl and/or p and q are both 0 or at least 1 or at least one of p and q is at least 2 and/or D is C3-C6 alkylene optionally substituted with one or more groups selected from hydroxyl, methoxy, methyl and ethyl.

US Pat. No. 9,453,110

CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS

CooperVision Internationa...

1. A HEMA-compatible polysiloxane having the structure of Formula 4:

wherein R1 is hydrogen, R2 is either hydrogen or a methyl group, k is an integer of 0 or 1, m is an integer of 0 to 60, n is an integer of 1 to 75, p
is an integer of 0 to 40, and q is an integer of 0 to 20,

wherein the HEMA-compatible bifunctional polysiloxane has an HLB value of at least 5, or has a hydroxyl group content of at
least 1 wt. % based on the average molecular weight of the polysiloxane, or has both an HLB value of at least 5 and has a
hydroxyl group content of at least 1 wt. %, and

wherein the HEMA-compatible bifunctional polysiloxane has a purity of at least 75%.

US Pat. No. 9,057,822

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens, comprising:
a polymeric lens body that is the reaction product of a polymerizable composition, said polymerizable composition comprising
(a) a first siloxane monomer represented by formula (3):

wherein m of formula (3) represents one integer from 3 to 10, n of formula (3) represents one integer from 1 to 10, R1 of formula (3) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (3) is independently either a hydrogen atom or a methyl group;

(b) at least one vinyl ether-containing cross-linking agent wherein the at least one vinyl ether-containing cross-linking
agent comprises a vinyl-ether containing cross-linking agent having at least one ethylene glycol unit present in its molecular
structure;

(c) at least one methacrylate-containing cross-linking agent; and
(d) at least one hydrophilic amide monomer having one N-vinyl group, wherein a ratio of total unit parts by weight of hydrophilic
amide monomers present in the polymerizable composition to a total unit parts by weight of vinyl ether-containing cross-linking
agents present in the polymerizable composition is a ratio of at least 200:1.

US Pat. No. 9,429,684

PRIMARY AMINE-CONTAINING SILICONE HYDROGEL CONTACT LENSES AND RELATED COMPOSITIONS AND METHODS

CooperVision Internationa...

16. A method of manufacturing a silicone hydrogel contact lens, comprising:
providing a miscible polymerizable composition, said polymerizable composition comprising
(a) at least one siloxane monomer in an amount of from 20 to 80 weight percent;
(b) at least one hydrophilic monomer in an amount of from 20 to 80 weight percent;
(c) at least one cross-linking agent;
(d) at least one polymerization initiator; and
(e) at least one primary amine-containing methacrylate monomer or at least one primary amine-containing methacrylamide monomer;
polymerizing the polymerizable composition in a contact lens mold assembly to form a polymeric lens body having, when hydrated,
an equilibrium water content of at least 30%, an oxygen permeability of at least 30 barrers, and a modulus of 0.3 to 1.2 MPa;
the polymeric lens body comprising a plurality of primary amine functional groups provided by polymerized units of the at
least one primary amine-containing methacrylate monomer or the at least one primary amine-containing methacrylamide monomer;

separating the polymeric lens body from the mold assembly;
contacting the separated polymeric lens body with an aqueous solution comprising an agent having an attached one or more complementary
functional groups, forming covalent bonds between the one or more complementary functional groups of the agent and the plurality
of primary amine functional groups of the polymeric lens body, thereby attaching the agent to the contacted polymeric lens
body; and

packaging the contacted polymeric lens body in a contact lens packaging solution in a contact lens package to form a finished
contact lens.

US Pat. No. 10,029,402

METHOD AND APPARATUS FOR MANUFACTURING CONTACT LENSES

CooperVision Internationa...

1. An apparatus for forming a contact lens mold half for use in manufacturing a contact lens, the apparatus comprising:an injection-molding unit including a first plate for carrying a plurality of first tool halves, and a second plate for carrying a plurality of second tool halves, at least one of the first plate and the second plate being arranged to reciprocate between (i) an open configuration in which the first plate and the second plate are spaced apart from one another, and (ii) a closed configuration in which the first plate and the second plate are in such close proximity to one another that the first and second tool halves, when carried by the first plate and the second plate, contact one another and together each pair of tool halves define an injection molding cavity for forming a contact lens mold half; and
a contact lens mold half removal unit including a rail, a gripper plate mounted on the rail, and a linear motor arranged to propel the gripper plate from (i) a receive position between the first plate and the second plate when the first plate and the second plate are in the open configuration, toward (ii) a deliver position; the gripper plate including a plurality of mold-removing elements for receiving mold halves from tool halves in the first plate or second plate when the gripper plate is in the receive position,
wherein the first plate and the second plate are arranged to begin to close from the open configuration to the closed configuration before the gripper plate has been fully removed from between the first plate and the second plate.

US Pat. No. 10,029,430

TRAY FOR USE IN MANUFACTURING CONTACT LENSES

CooperVision Internationa...

1. A tray for holding contact lens mold assemblies during thermal curing of a contact lens precursor material in an oven to form contact lenses, wherein the tray comprises:(a) a plurality of plates; and
(b) a frame supporting the plates, the frame being configured to co-operate with identical frames so that a plurality of the trays can be stacked vertically to form a tray stack;wherein each plate comprises:(i) a plurality of support structures each arranged to support one contact lens mold assembly during curing; and
(ii) a plurality of channels connecting the support structures, to allow fluid communication between the support structures in the tray stack during curing;and wherein each plate is a carbon-fiber reinforced polymer plate.

US Pat. No. 9,855,712

METHODS OF MANUFACTURING AND APPARATUS USEFUL IN MANUFACTURING TORIC CONTACT LENSES

COOPERVISION INTERNATIONA...

1. A method of manufacturing a toric contact lens comprising:
providing a toric contact lens insert without an orientation mark to be used in forming a toric contact lens mold section,
the toric contact lens insert including a bottom and a groove across the bottom;

placing the toric contact lens insert without an orientation mark in an orientation mark fixture comprising a single piece
fixture housing structured to hold a toric contact lens insert at an angle specified for an orientation mark, and a pin, the
fixture housing having intersecting surfaces which form a generally V-shaped region on which the toric contact lens insert
is located, the generally V-shaped region contacting the toric contact lens insert at two different contact points, lines
or areas;

orienting the toric contact lens insert without an orientation mark in the orientation mark fixture, the orienting the toric
contact lens insert comprises placing the pin into both the fixture and the groove of the toric contact lens insert, thereby
orienting the toric contact lens insert in the fixture with respect to the location of the groove on the bottom of the toric
contact lens insert;

fixing the toric contact lens insert without an orientation mark to the orientation mark fixture;
forming an orientation mark on the toric contact lens insert fixed to the orientation mark fixture;
removing the toric contact lens insert with the orientation mark from the orientation mark fixture;
using the toric contact lens insert with the orientation mark to form a toric contact lens mold section; and
using the toric contact lens mold section to form a toric contact lens.

US Pat. No. 9,764,501

CONTACT LENS MOLD PARTS, CONTACT LENS MOLD ASSEMBLIES, AND METHODS OF MAKING CONTACT LENSES

CooperVision Internationa...

22. A contact lens mold part comprising:
a lens-forming surface having a central axis and a circumferential edge;
a planar stop surface extending radially outwardly from the circumferential edge of the lens-forming surface in a plane perpendicular
to the central axis of the lens-forming surface;

an intermediate region extending from the planar stop surface;
an annular recessed section extending radially outwardly of and intersecting with the planar stop surface, the annular recessed
section comprising an annular ridge therein having a planar surface that lies in the plane of the planar stop surface; and

an alignment surface extending from the intermediate region in a direction parallel to the central axis of the lens-forming
surface.

US Pat. No. 9,498,924

OPHTHALMIC LENS MOLDS WITH LOW LEVELS OF UV LIGHT TRANSMITTANCE, OPHTHALMIC LENSES MOLDED THEREIN, AND RELATED METHODS

CooperVision Internationa...

1. A method of manufacturing a silicone hydrogel contact lens body, comprising:
providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured
to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to
mold a posterior surface of a contact lens, the molding surface of at least one of the first mold member and the second mold
member comprising at least one thermoplastic polymer having a level of UV transmittance of from 0.01% to 3.00%, the first
mold member and the second mold member being configured to form a lens-shaped cavity therebetween when combined as a mold
assembly;

placing a polymerizable composition comprising a) at least one silicon-containing monomer, silicon-containing macromer, silicon-containing
prepolymer, or any combination thereof, and b) at least one hydrophilic monomer in the first mold member;

assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped
cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; and

directing UV light through the mold assembly into the lens-shaped cavity to cure the polymerizable composition in the mold
assembly, forming a cast-molded polymerized reaction product in the lens-shaped cavity of the mold assembly, the polymerized
reaction product comprising a silicone hydrogel contact lens body,

wherein the level of UV transmittance of the at least one thermoplastic polymer is determined at 370 nm using a sample of
the thermoplastic polymer having a thickness of from 0.6 mm to 0.7 mm, and the at least one thermoplastic polymer has a high
level of UV light diffusivity, and is effective to reduce variation in UV light intensity between an exterior surface of the
mold assembly and the lens-shaped cavity by at least 5% during the step of directing UV light.

US Pat. No. 9,864,103

PHOSPHINE-CONTAINING HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A method of manufacturing a hydrogel contact lens, comprising:
providing a polymerizable composition comprising
(a) at least one hydrophilic monomer, and
(b) at least one phosphine-containing compound, wherein the at least one phosphine-containing compound is present in an unoxidized
form at the time it is combined with the at least one hydrophilic monomer in the polymerizable composition, and

(c) at least one thermal initiator, wherein (b) and (c) are different from each other; and
(d) thermally curing the polymerizable composition to form a polymeric lens body.

US Pat. No. 9,804,417

WETTABLE SILICONE HYDROGEL CONTACT LENSES AND RELATED COMPOSITIONS AND METHODS

CooperVision Internationa...

1. A method for producing a silicone hydrogel contact lens, comprising:
providing a polymerizable silicone hydrogel lens precursor composition in a contact lens shaped cavity of a non-polar resin
contact lens mold, the polymerizable silicone hydrogel precursor composition comprising a silicone-containing component and
a non-silicone containing component, the non-silicone containing component being present in an amount between about 10% to
about 60% (w/w) based upon the weight of all reactive components of the precursor composition and said non-silicone containing
component comprising an N-vinyl pyrrolidone (NVP) monomer and a N,N-dimethylacrylamide (DMA) monomer, and the contact lens
mold comprising a first contact lens mold member and a second contact lens mold member assembled together;

polymerizing the polymerizable silicone hydrogel lens precursor composition in the non-polar resin contact lens mold using
heat or ultraviolet light to form a pre-extracted polymerized silicone hydrogel contact lens product having a dry weight,
the pre-extracted silicone hydrogel contact lens product having a removable monomeric component in an amount of at least 10%
(w/w) based on the dry weight of the pre-extracted polymerized silicone hydrogel contact lens product;

extracting and hydrating the pre-extracted polymerized silicone hydrogel contact lens product by contacting the pre-extracted
polymerized silicone hydrogel contact lens product with an extraction media to produce a silicone hydrogel contact lens having
a dry weight no greater than 90% of the dry weight of the pre-extracted polymerized silicone hydrogel contact lens product;
and

packaging the silicone hydrogel contact lens in a contact lens package,
wherein the silicone hydrogel contact lens has an advancing contact angle less than 90 degrees, a tensile modulus less than
1.0 MPa, an oxygen permeability from about 110 barrers to about 120 barrers, and a water content from about 45% to about 55%
by weight.

US Pat. No. 10,042,183

OPHTHALMIC DEVICE MOLDS FORMED FROM WATER-SOLUBLE VINYL ALCOHOL COPOLYMER, OPHTHALMIC DEVICES MOLDED THEREIN, AND RELATED METHODS

CooperVision Internationa...

1. A mold for cast molding an ophthalmic device, comprising:a mold comprising a molding surface and a non-molding region, wherein at least the molding surface of the mold member comprises at least one unmodified water-soluble vinyl alcohol copolymer;
wherein the at least one unmodified water-soluble vinyl alcohol copolymer is a vinyl alcohol copolymer essentially free of ethylene units.

US Pat. No. 9,322,960

METHOD OF MAKING A CONTACT LENS

CooperVision Internationa...

1. A contact lens comprising a reaction product of a polymerisable formulation comprising:
(i) from 20 to 35 weight percent of at least one fluorine-containing silicone monomer having the formula:

wherein n is from 1 to 10;
(ii) from 15 to 35 weight percent of at least one non-fluorine containing silicone monomer;
(iii) from 25 to 60 weight percent N-vinyl pyrrolidone or N-methyl-N-vinyl acetamide;
(iv) from 2 to 10 weight percent 2-hydroxyethyl methacrylate,
wherein the total amount of components (i) and (ii) is less than 50 weight percent.

US Pat. No. 9,121,998

SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A silicone hydrogel contact lens, comprising:
an ophthalmically acceptably clear polymeric lens body, the polymeric lens body being the reaction product of a miscible polymerizable
composition comprising

(a) at least one hydrophilic amide monomer having one N-vinyl group present in an amount of from 30 to 60 unit parts by weight;
(b) 2-hydroxyethyl methacrylate (HEMA) present in an amount of from 10 to 50 unit parts by weight; and
(c) a first siloxane monomer component, wherein a total amount of siloxane monomer(s) present in the polymerizable composition
is an amount of from 15 to 40 unit parts by weight, the first siloxane monomer component comprising at least one siloxane
monomer selected from a siloxane monomer of formula (1), a siloxane monomer of formula (2), a siloxane monomer of formula
(3), or any combination thereof, wherein the siloxane monomer of formula (1) is a siloxane monomer represented by formula
(1):


wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the siloxane of formula (2) is a siloxane monomer
represented by formula (2):


wherein R1 of formula (2) is selected from either hydrogen or a methyl group; R2 of formula (2) is selected from either of hydrogen or a C 1-4 hydrocarbon group; m of formula (2) represents an integer of from 0 to 10; n of formula (2) represents an integer of from
4 to 100; a and b of formula (2) represent integers of 1 or more; a+b of formula (2) is equal to 20-500; b/(a+b) is equal
to 0.01-0.22, and the configuration of siloxane units includes a random configuration; the siloxane monomer of formula (3)
is a siloxane monomer represented by formula (3):


wherein n of formula (3) is an integer from 0-30.

US Pat. No. 10,139,522

SILICONE ELASTOMER-SILICONE HYDROGEL HYBRID CONTACT LENSES

CooperVision Internationa...

1. A silicone elastomer-silicone hydrogel hybrid contact lens comprising:a) a silicone elastomer layer comprising an anterior side and a posterior side; and
b) a silicone hydrogel layer adhered to the posterior side of the silicone elastomer layer; wherein a delamination-resistant bond is present between the silicone elastomer layer and the silicone hydrogel layer, and wherein the silicone hydrogel layer has a percent swell of from about ?5% to less than 10%.
US Pat. No. 9,789,058

OPHTHALMIC COMPOSITION FOR THE TREATMENT OF OCULAR INFECTION

CooperVision Internationa...

1. An ophthalmic composition for use in the treatment of an ocular infection when the ophthalmic composition is administered
to an eye of a patient, or the prophylaxis of an ocular infection when the ophthalmic composition is administered to an eye
of a patient before or after the introduction of an inoculum of an ocular pathogen, said composition consisting essentially
of a pharmaceutically-acceptable carrier, an amount of ?-polylysine (?PL) effective for said treatment, and optionally at
least one non-active agent, wherein the ophthalmic composition is provided as a liquid in an eye-drop dispensing bottle or
vial, or as a unit dose ocular insert for placement in a cul de sac of the patient's eye, wherein the composition comprises
no preservative agent in addition to the ?-polylysine (?PL).
US Pat. No. 9,789,654

METHOD OF MANUFACTURING WETTABLE SILICONE HYDROGEL CONTACT LENSES

CooperVision Internationa...

1. A method of manufacturing a silicone hydrogel contact lens, said method comprising:
a. curing a polymerizable composition comprising at least one siloxane monomer and at least one hydrophilic vinyl-containing
monomer in a contact lens mold to form a polymeric lens body; and

b. washing and packaging the polymeric lens body to provide a silicone hydrogel contact lens having a first contact angle;
wherein said contact lens mold comprises a molding surface coated with a hydrophilic coating comprising at least one hydrophilic
polymer,

wherein the hydrophilic coating is not solubilized by the polymerizable composition during the curing step, and
the silicone hydrogel contact lens is substantially free of the hydrophilic polymer from the hydrophilic coating, and
the first contact angle is lower than a second contact angle of a control silicone hydrogel contact lens cured in an uncoated,
but otherwise identical, contact lens mold and manufactured using a method that is identical to the method of manufacturing
the silicone hydrogel contact lens, and wherein the hydrophilic polymer is free of primary amine groups and has an average
molecular weight of about 10,000 daltons to about 200,000 daltons.

US Pat. No. 9,867,533

SYSTEMS AND METHODS FOR DETERMINING AN ANGLE OF REPOSE OF AN ASYMMETRIC LENS

COOPERVISION INTERNATIONA...

1. A method for operating a device or devices to determine an angle of repose of a contact lens on an eye, the device or devices
including a display, a camera with a camera lens, an orientation sensor, a data processor, and a user input device, comprising:
displaying a view finder image from the camera on the display prior to capturing the image;
displaying an orientation graphic on the display using the orientation sensor while displaying the view finder image, the
orientation graphic to indicate orientation of the camera lens around a line of sight axis normal to the camera lens around
a horizontal axis and around a vertical axis;

capturing and storing an image using the camera;
executing a graphical user interface using the display, the graphical user interface including a frame or frames including
the captured image, and graphical constructs prompting input identifying a set of locations on the captured image usable to
define a location of the contact lens in the image, and a location usable to define an angle of repose of the contact lens
in the image; and

accepting input data responsive to the graphical constructs that identifies the set of locations to define the location of
the contact lens in the captured image and the location to define the angle of response of the contact lens in the captured
image.

US Pat. No. 10,139,521

SILICONE ELASTOMER-HYDROGEL HYBRID CONTACT LENSES

CooperVision Internationa...

1. A silicone elastomer-hydrogel hybrid contact lens comprising:a) a silicone elastomer layer comprising an anterior side and a posterior side; and
b) a hydrogel layer adhered to the posterior side of the silicone elastomer layer, wherein the hydrogel layer is formed by curing a polymerizable composition comprising an elastomer-swellable monomer having an HLB value of less than 4 or a molecular weight of up to 1,200 daltons or both; and
c) a delamination-resistant bond between the silicone elastomer layer and the hydrogel layer, wherein the delamination-resistant bond is formed by the elastomer-swellable monomer.

US Pat. No. 9,938,034

METHOD AND APPARATUS RELATING TO MANUFACTURE OF MOLDS FOR FORMING CONTACT LENSES

CooperVision Internationa...

1. An apparatus for manufacturing mold halves for use in the manufacture of contact lenses, the apparatus comprising:an injection-molding apparatus including a plate, a removable collet in the plate, and a clamp configured to hold the removable collet in the plate, wherein the removable collet comprises a frustoconical rear portion and a circumferential groove upon which the clamp acts;
a tool half mounted in the removable collet;
a collet store for storing at least one removable collet configured to be inserted into the plate, wherein the collet store comprises a housing for receiving a plurality of removable collets, and a turntable on which the housing is mounted; and
a collet-exchange robot comprising at least one collet extraction head, wherein the collet-exchange robot is configured to grip a removable collet from the plate, move the removable collet to the collet store, insert the removable collet into the collet store, grip a replacement collet from the collet store, move the replacement collet to the plate, and insert the replacement collet into the plate,wherein the turntable being rotatable from a first position wherein a removable collet is manually loadable into the housing, to a second position wherein the removable collet is removeable from the collet store by the collet-exchange robot.

US Pat. No. 9,937,640

APPARATUS AND METHOD FOR CLOSURE OF OPHTHALMIC LENS MOLDS

CooperVision Internationa...

1. A method of manufacturing an ophthalmic lens, the method comprising:providing a male mold half having a convex mold surface, and a complementary female mold half having a concave mold surface, wherein the female mold half retains a polymerizable composition for forming an ophthalmic lens between the convex mold surface and the concave mold surface;
moving one of the mold halves toward the other mold half until the convex mold surface of the male mold half contacts the polymerizable composition retained in the female mold half;
contacting a surface of the female mold half with a surface of the male mold half by applying a force to bring the male mold half and the female mold half together, wherein a velocity at which the male mold half is moved toward the female mold half during the contacting is predetermined based on a previously measured force applied to contact a different pair of mold halves with one another;
measuring the force applied during the contacting; and
determining that the mold halves have formed a closed mold assembly when the force is greater than or equal to a predetermined threshold force.

US Pat. No. 10,137,612

METHODS AND APPARATUS FOR MANUFACTURE OF OPHTHALMIC LENSES

CooperVision Internationa...

1. A method of removing a contact lens from a lens mold portion carrying a contact lens, the method comprising reciprocally displacing a region of the mold portion to thereby cause an edge portion of the contact lens to become detached from the mold portion, wherein the reciprocal displacement comprises a plurality of cycles, each cycle comprising motion in a first direction, followed by motion in a second, opposite direction.

US Pat. No. 10,363,711

METHOD OF MAKING CONTACT LENSES

CooperVision Internationa...

1. A method of making a contact lens, the method comprising:(i) providing a first master mould for producing a first mould half and a second master mould for producing a second mould half;
(ii) producing at least one precursor mould comprising the first mould half and the second mould half, wherein the first mould half is for providing a first lens surface having at least one optical feature and the second mould half is for providing a second lens surface which requires lathing to provide at least one added optical feature;
(iii) producing a moulded precursor contact lens in each of the at least one precursor mould, wherein the step of producing the lens results in at least one identifiable undesirable attribute;
(iv) identifying the at least one undesirable attribute on the moulded precursor contact lens;
(v) determining the extent of the at least one undesirable attribute;
(vi) providing at least one lens producing mould formed from the first master mould and second master mould, each lens producing mould having a first mould half and a second mould half, wherein the first mould half is for providing a first lens surface having at least one optical feature and the second mould half is for providing a second lens surface which requires lathing to provide at least one added optical feature;
(vii) producing the contact lens in at least one lens producing mould;
(viii) removing the second mould half, whereby the contact lens remains positioned on the first mould half; and
(ix) lathing the second lens surface using a lathe tool, wherein the path of the lathe tool is controlled by a computer programme, and wherein the computer programme adjusts the path to compensate for the undesirable attribute of the moulded precursor contact lens identified in step (iv),
wherein the at least one undesirable attribute comprises an eccentricity of the precursor test contact lens from the centre of the of the mould half, and the eccentricity is characterized by defining an angle and magnitude of offset.

US Pat. No. 10,390,593

CONTACT LENS BLISTER PACKAGES

CooperVision Internationa...

1. A contact lens blister package comprising:a thermoplastic base member comprising a proximal end region having a grip portion, a distal end region, a first side region extending from the proximal end region to the distal end region, a second side region opposing the first side region, and a cavity configured to contain a packaging solution and a contact lens when placed inside the cavity, the cavity being located between the proximal end region and the distal end region and between the first side region and the second side region; wherein
the cavity comprises a bottom wall having a bottom wall perimeter and a sidewall extending upwardly from the bottom wall perimeter to an upper cavity edge defining a cavity perimeter and including a substantially linear upwardly extending sidewall portion;
the cavity perimeter comprises a substantially linear portion and a non-linear portion opposing the substantially linear portion; and
a plane formed at the intersection of the bottom wall perimeter with the sidewall slopes away from the substantially linear portion of the cavity perimeter.

US Pat. No. 10,364,082

CONTACT LENS PACKAGING AND METHODS OF MANUFACTURING PACKAGED CONTACT LENSES

CooperVision Internationa...

1. A contact lens package, comprising:a plurality of sealed contact lens packages arranged in an array and having perforations in the sealing member at a location corresponding to adjacent base members, wherein each sealed contact lens package includes a base member, and a sealing member coupled to the base member to provide a sealed cavity, and an unworn contact lens is provided in a contact lens packaging solution within the sealed cavity;
a wrap comprising at least one panel that comprises a printing surface that comprises a unique device identifier in both a human readable form including numbers or letters, or combinations thereof, and a machine readable form including a barcode; and
the base member is a thermoplastic material comprising a cavity and a substantially planar surface surrounding the cavity, said substantially planar surface providing a sealing surface for the sealing member; and the wrap includes an adhesive adhering the wrap to the sealing member; and
wherein the wrap includes a plurality of first panels corresponding to the number of sealed contact lens packages, each first panel including a printed surface with the unique device identifier in both human readable form and machine readable form.

US Pat. No. 10,239,266

METHOD AND APPARATUS FOR MANUFACTURING CONTACT LENSES

CooperVision Internationa...

1. A method of forming a contact lens, the method comprising:providing a polymerizable contact lens precursor material in a cavity defined by at least one cavity-defining portion of at least one mold member, the at least one cavity-defining portion comprising a material that is soluble in a solvent in which the contact lens is not soluble;
polymerizing the polymerizable contact lens precursor material to form an unhydrated contact lens in the cavity; and
holding a support portion of the at least one mold member whilst immersing the at least one cavity-defining portion in the solvent to dissolve at least part of the material that is soluble of the at least one cavity-defining portion, so that the contact lens is released from the cavity;
wherein more of the polymerizable contact lens precursor material is provided to the cavity than is required to fill the cavity, so that there is an excess of the polymerizable contact lens precursor material;
wherein,
the excess of the polymerizable contact lens precursor material passes into a channel defined by at least one cavity-defining portion of at least one mold member; and
a portion of the excess of the polymerizable contact lens precursor material passes from said channel into a channel defined by the support portion of the at least one mold member, so that, after the polymerizable contact lens precursor material is polymerized and the material that is soluble of the at least one cavity-defining portion is dissolved, the excess polymerizable contact lens precursor material forms a solid that is retained by the support portion.
US Pat. No. 10,422,927

METHOD OF MANUFACTURING SILICONE HYDROGEL CONTACT LENSES HAVING REDUCED RATES OF EVAPORATION

CooperVision Internationa...

1. A method of manufacturing a silicone hydrogel contact lens comprising:a) providing a contact lens mold comprising a first lens-forming surface to mold one side of said hydrogel contact lens and a second lens-forming surface to mold opposite side of said hydrogel contact lens, wherein the first lens-forming surface has a higher polarity than the second lens-forming surface;
b) curing a polymerizable composition comprising at least one siloxane monomer and at least one hydrophilic monomer in the contact lens mold to form a polymeric lens body;
c) hydrating the polymeric lens body to provide a silicone hydrogel contact lens having a first surface formed by the first lens-forming surface of the contact lens mold and a second surface formed by the second lens-forming surface of the contact lens mold; and
d) sealing the silicone hydrogel contact lens in a package,wherein the silicone hydrogel contact lens has a lower ionoflux and/or a lower evaporation rate than a control contact lens manufactured by an identical method except that the second lens-forming surface has the same polarity as the first lens-forming surface, and wherein after the curing step the polymeric lens body is subjected to a surface modification treatment to increase wettability of the second surface of the silicone hydrogel contact lens, and the surface modification treatment is selected from air plasma, or UV-ozone, or corona discharge.

US Pat. No. 10,406,768

METHOD AND APPARATUS FOR MANUFACTURING CONTACT LENS MOULDS

CooperVision Internationa...

1. A collet for holding a contact lens mold half during machining of a surface of the mold half, the collet comprising a disc having a face and defining:a central structure, at the center of the face, for receiving a head portion of the mold half, and
a recess, in the face, for receiving a tail portion of the mold half, the recess extending from the central structure along a radius of the disc;
wherein the recess is elongate and shaped and sized to receive substantially the entire length of the tail portion of the mold half.

US Pat. No. 10,383,417

CONTACT LENS CASE AND RELATED METHODS AND KITS

CooperVision Internationa...

1. A method of treating a contact lens including the following steps:providing a case for holding one or more contact lenses, the case comprising an upper part and a lower part wherein the upper part comprises a cover mounted on a compression member, the cover mounted for movement such that the cover rotates with respect to the compression member;
providing an inner pod comprising a base portion defining one or more compartments and a re-sealable lid;
partially removing the lid of the inner pod;
placing a contact lens in a compartment of the inner pod;
replacing the lid of the inner pod;
placing the inner pod on the lower part of the case;
closing the case so that the inner pod is enclosed in the case;
moving the upper part relative to the lower part by rotating the cover with respect to the compression member so that the inner pod is compressed between the upper and lower parts and the lid seals the one or more compartments to form a water-tight seal between the lid and the base portion.

US Pat. No. 10,336,022

MANUFACTURE OF OPHTHALMIC LENSES

CooperVision Internationa...

1. A method of manufacturing an ophthalmic lens using a first mold portion and a puck assembly, said puck assembly comprising a carrier puck, wherein the puck assembly supports at least one of the first mold portion and the ophthalmic lens during at least two of the following ophthalmic lens manufacturing steps:a. assembling the first mold portion and a second mold portion into a mold assembly including a lens-defining cavity containing a lens precursor material;
b. curing the lens precursor material in the mold assembly to form a lens;
c. separating the mold assembly such that the lens remains attached to the first mold portion;
d. detaching the lens from the first mold portion;
e. extracting unwanted material from the lens;
f. hydrating the lens;
g. inspecting the lens;
h. packaging the lens; andcharacterised in that the carrier puck is arranged and configured to interface with a plurality of different step-specific puck elements and the method includes:i. providing a first step-specific puck element;
ii. combining the first step-specific puck element with the carrier puck and carrying out a first ophthalmic lens manufacturing step on the first mold portion and/or the lens carried by the carrier puck; and then
iii. providing a second step-specific puck element;
iv. combining the second step-specific puck element with the carrier puck and carrying out a second ophthalmic lens manufacturing step on the first mold portion and/or the lens carried by the carrier puck,wherein the puck assembly supports at least one of the first mold portion and the lens during the majority of the ophthalmic lens manufacturing steps a. to h.

US Pat. No. 10,249,388

METHODS AND SYSTEMS FOR REPLENISHING SUPPLIES IN A PRODUCT ARRAY

CooperVision Internationa...

1. A method comprising:displaying a digital image of an array of storage spaces on a client device having a screen to display the digital image of the array of storage spaces, wherein each storage space of the digital image of the array of storage spaces represents a contact lens prescription for a contact lens;
placing at least a three by three array of the digital image of the array of storage spaces displayed on the client device in a same general space as a three by three array of physical storage spaces so that the digital image of the array of storage spaces and the array of physical storage spaces may be viewed by a user, wherein each physical storage space is sized and shaped to store at least one contact lens package having a contact lens prescription and wherein the contact lens prescription of each storage space of the digital image of the array of storage spaces corresponds to the contact lens prescription of a contact lens for each corresponding storage space in the three by three array of physical storage spaces;
receiving, in the client device, a selection of a chosen storage space within the three by three array of the digital image of the array of storage spaces that corresponds to an empty storage space within the three by three array of the physical array of storage spaces, said selecting of the empty storage space defining a first order selection;
receiving, in the client device, an input of a number that corresponds to a quantity of contact lens packages to order for the first order selection; and
confirming an order in a shopping cart using the client device.