US Pat. No. 9,357,931

MEDICAL SYSTEMS AND METHODS

Carl Zeiss Meditec AG, J...

1. A method, comprising:
recording a first plurality of images of a plurality of points of at least one blood vessel, each of the plurality of images
comprising fluorescent light intensity information at each of the plurality of points of the at least one blood vessel;

for each of the plurality of points of the at least one blood vessel, analyzing the first plurality of recorded images to
determine a maximum fluorescent light intensity at the point of the at least one blood vessel; and

for each of the plurality of points of the at least one blood vessel, displaying a first image that represents the maximum
fluorescent light intensity at the point of the at least one blood vessel.

US Pat. No. 9,274,303

ADJUSTING DEVICE FOR AN OPTICAL SYSTEM

Carl Zeiss Meditec AG, J...

1. An adjusting device for an optical system, the adjusting device comprising:
a first slider for a first optical element and said first slider being arranged so as to be displaceable along an axial direction;
a second slider for a second optical element and said second slider being arranged so as to be displaceable along said axial
direction;

a control element defining a control cam contour and being fixedly mounted relative to said axial direction;
a coupler configured as a single part and being arranged between said first slider, said second slider and said control cam
contour;

a force element applying a force between said first and said second sliders so as to cause said coupler to be in contact with
said first slider at a first point and with said second slider at a second point and with said control cam contour at a third
point;

said coupler including a first lever arm formed between said first point and said third point and a second lever arm formed
between said second point and said third point; and,

said device being so configured that, with a movement of said coupler, at least one of said first and second lever arms is
changeable with respect to the length thereof.

US Pat. No. 9,084,667

TREATMENT DEVICE FOR OPERATIVELY CORRECTING DEFECTIVE VISION OF AN EYE, METHOD FOR PRODUCING CONTROL DATA THEREFOR AND METHOD FOR OPERATIVELY CORRECTING DEFECTIVE VISION OF AN EYE

Carl Zeiss Meditec AG, J...

1. A treatment apparatus for operatively correcting refractive error in an eye, the treatment apparatus comprising:
a laser device which is controlled by a control device;
the laser device separating corneal tissue by applying laser radiation and including a laser and scanners, the scanners each
comprising mirrors, optics or a combination of mirrors and optics;

the control device being programmed with an algorithm that activates the laser device including the laser and the scanners,
to emit the laser radiation into the cornea at a focus positioned by operation of the scanners wherein a lenticular volume
is isolated in the cornea, removal of the lenticular volume from the cornea effecting a desired refractive correction;

wherein the control device and algorithm predefine the lenticular volume during activation of the laser device to have a minimum
thickness portion that has a minimum thickness (dM) in a range of between 5 ?m and 50 ?m, the minimum thickness portion being
at an edge of the lenticular volume in correction of myopia and in a region of an axis of vision in correction of hyperopia.

US Pat. No. 9,510,754

ILLUMINATION ARRANGEMENT AND SURGICAL MICROSCOPE INCORPORATING THE SAME

Carl Zeiss Meditec AG, J...

1. An illumination arrangement for an optical instrument defining a viewing beam path, the illumination arrangement comprising:
an illumination optic defining an optical axis;
a light source for generating an illumination beam path for illuminating an object field at a specific illumination angle
with said viewing beam path;

a mirror arranged in said illumination beam path and being configured to deflect the light of said light source;
said mirror having a longitudinal extent along said optical axis;
said light source having a light-emitting surface region variable perpendicularly to said optical axis without movable parts;
and,

said illumination optic being configured to image an illumination pupil within said longitudinal extent of said mirror.

US Pat. No. 9,498,120

METHOD AND SYSTEM FOR OPTICAL COHERENCE ELASTOGRAPHY OF POSTERIOR PARTS OF THE EYE

Carl Zeiss Meditec AG, J...

1. A method for optical coherence elastography of a tissue of an eye, the method comprising:
introducing at least a portion of a probe into a vitreous humor of the eye, the portion of the probe comprising a vibration
element;

generating time resolved images of the tissue of the eye, the tissue being located more posterior than the vibration element
of the probe, wherein the time resolved images of the tissue are generated by optical coherence tomography;

exciting the vibration element to ultrasonic vibrations making the tissue vibrate or oscillate;
measuring a displacement of the tissue in the time resolved images; and
calculating elasticity values of the tissue from the displacement.

US Pat. No. 9,320,438

MEDICAL SYSTEMS AND METHODS

Carl Zeiss Meditec AG, J...

1. A method of treating an aneurysm, the method comprising:
exposing an aneurysm at a surgical site;
injecting a fluorescent dye into a blood vessel that includes the aneurysm;
capturing a first set of images of the surgical site with a camera;
analyzing the first set of images captured by the camera in a signal processing and analysis unit;
applying a clip to the aneurysm to clamp off the aneurysm;
after applying the clip to the aneurysm, capturing a second set of images of the surgical site with the camera;
analyzing the second set of images captured by the camera in a signal processing and analysis unit; and
comparing the first set of images with the second set of images to determine the effectiveness of the clip to clamp of the
aneurysm.

US Pat. No. 9,517,126

OPHTHALMOLOGIC IMPLANT

Carl Zeiss Meditec AG, J...

1. An ophthalmologic implant including at least one mark comprising a fluorescent dye with an emission maximum outside of
the light spectrum visible to a human,
wherein the fluorescent dye does not substantially influence light transmission of the implant in the visual spectral range
and is from at least one structural class selected from the group consisting of cyanines, merocyanines, phthalocyanines, rhodamines,
porphyrines, chlorophylls, triarylmethanes, xanthenes, oxazines, thiazines, safranines, heterocyclic pyrylium and thiapyrylium
salts, perrylenes, terrylenes, quaterrylenes, quaterneles, azo dyes, metal complexes, and chinones, and

the at least one mark designating posture or position of the implant when illuminated with white light or with light of a
spectral range that effects corresponding fluorescence of the dye outside of the light spectrum visible to the human.

US Pat. No. 9,463,115

APPARATUS FOR INDIVIDUAL THERAPY PLANNING AND POSITIONALLY ACCURATE MODIFICATION OF AN OPTICAL ELEMENT

CARL ZEISS MEDITEC AG, J...

1. A navigation apparatus for optically analyzing an inner structure of an optical element and for processing the optical
element, the apparatus comprising:
a detection device having an aperture smaller than 0.25; and
a processing device configured to process the inner structure and adapted to be guided along or in a fixed relationship to
the inner structure of the optical element.

US Pat. No. 9,351,635

ASSEMBLY AND METHOD FOR THE AUTOMATIC ROUGH POSITIONING OF OPHTHALMOLOGICAL EQUIPMENT

Carl Zeiss Meditec AG, J...

1. An assembly for automatic rough positioning of ophthalmological devices, comprising:
a positioning aid; and
a control unit operably coupled to the positioning aid that automatically aligns the visual axis of the eye with the optical
axis of the ophthalmological device;

wherein the positioning aid that automatically aligns the visual axis of the eye with the optical axis of the ophthalmological
device includes a chin rest and a forehead support operably coupled to appropriate controllable actuating devices; and

further comprising an additional measuring device that is operably connected to the control unit of the ophthalmological device
and wherein the additional measuring device includes a three dimensional camera that captures three dimensional image data
of a face of a patient;

wherein the control unit calculates anatomically-to-scale three-dimensional geometry of the face of a patient from the three
dimensional image data including dimensions of the face in a first plane and in a second plane orthogonal to the first plane.

US Pat. No. 9,480,399

ILLUMINATION DEVICE FOR AN OPTICAL VIEWING APPARATUS

Carl Zeiss Meditec AG, J...

1. An illumination device for an optical viewing apparatus, the illumination device defining an illumination beam path and
comprising:
an illumination light source having mutually independently controllable individual light sources arranged in a two-dimensional
array in a first plane;

illumination optics defining an optical axis;
said illumination optics forming a second plane conjugated with respect to said first plane;
a diaphragm unit arranged in said second plane;
said diaphragm unit having a plurality of apertures; and,
said apertures being assigned to corresponding ones of said individual light sources;
said apertures have a size and shape adapted to respective images of said individual light sources in said second plane;
said illumination optics define a first main plane (H) and a second main plane (H?);
said first main plane (H) and said first plane define a first distance (s) therebetween;
said second main plane (H?) and said second plane define a second distance (s?) therebetween;
wherein the following relationship is satisfied for a magnification scale:
1?|s'/s|?4.

US Pat. No. 9,129,366

MEDICAL SYSTEMS AND METHODS

Carl Zeiss Meditec AG, J...

1. A method, comprising:
recording a first plurality of images of a region of a blood vessel;
analyzing the first plurality of recorded images to determine a time at which a predetermined fluorescent light intensity
was reached for each of multiple points on each of the first plurality of recorded images; and

displaying a first image that represents a relative amount of time for each point of the first plurality of recorded images
to reach the predetermined fluorescent light intensity.

US Pat. No. 9,046,688

SURGICAL MICROSCOPE WITH ENLARGED WORKING DISTANCE

CARL ZEISS MEDITEC AG, J...

1. A surgical microscope, comprising:
an imaging system that provides a magnified multidimensional image of an object disposable in a focal plane of the imaging
system along at least one optical imaging path, the imaging system comprising an objective, the objective comprising at least
two lens groups through which the at least one optical imaging path passes one after another, and which define the focal plane
of the imaging system,

wherein at least one lens group of the objective is moveable along its optical axis relative to the at least one other lens
group of the objective,

wherein the objective's first lens group which is located directly adjacent to the focal plane along the at least one optical
imaging path consists of at least three optical lenses and has altogether a negative optical power, and

wherein the absolute value of the focal length of the first lens group of the objective does altogether not exceed 35% of
the absolute value of a minimum focal length of the objective.

US Pat. No. 9,084,564

SYSTEM FOR DETERMINING THE TOPOGRAPHY OF THE CORNEA OF AN EYE

Carl Zeiss Meditec AG, J...

1. A system for determining the topography of the cornea of an eye, comprising:
an element having a fresnel structure for generating rings similar to a Placido disk that are reflected from the cornea;
an illuminating unit arranged in an illuminating beam path;
an image capturing unit arranged in a detecting beam path;
a control and analysis unit;
wherein the element for generating rings similar to a Placido disk comprises a fresneled axicon including annular structures
of different radii that image light of the illuminating unit at different angles at the cornea of the eye, the fresneled axicon
having at least one conical refractive surface; and

further comprising a first optical element that illuminates an entire surface of the fresneled axicon with annular plane waves;
a second optical element that separates illuminating and detecting beam paths, the first optical element and the second optical
element being arranged between the illuminating unit and at least one surface of the fresneled axicon; and

the image capturing unit, comprising an imaging system and an image sensor being structured for telecentric, distance-independent
image detection.

US Pat. No. 9,462,938

METHOD FOR DETERMINING THE POWER OF AN INTRAOCULAR LENS

Carl Zeiss Meditec AG, J...

1. A method for calculating a power of an intraocular lens comprising:
determining a first location of a crystalline lens equator based on a combination of anterior chamber depth, crystalline lens
thickness and anterior radius of curvature of the crystalline lens;

using the determined first location of the crystalline lens equator to predict a second location of an intraocular lens equator;
and

using the second location of the intraocular lens equator that is predicted in a calculation to determine the power of the
intraocular lens.

US Pat. No. 9,370,445

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Carl Zeiss Meditec AG, J...

1. A treatment apparatus for surgical correction of defective eyesight in an eye of a patient, comprising a laser device which
separates corneal tissue by irradiation of pulsed laser radiation to a focal point located within the corneal tissue, the
laser device being controlled by a controller, wherein the controller controls the laser device such that said laser radiation
is focused on and applied to target points arranged in a pattern in the cornea, and the controller provides control data to
the laser device, wherein the control data specifies the target points to be points spaced apart on a path curve over which
a focus of the laser radiation is shifted, wherein the control data causes the laser device to shift the focused laser radiation
along the path curve via the target points of the pattern and to emit pulses of the pulsed laser radiation into the cornea
at the target points and also to emit pulses of the pulsed laser radiation at additional intermediate points of laser application
located between the target points on said path wherein the additional intermediate points of laser application are not specified
target points of the control data.

US Pat. No. 9,044,142

SURGICAL OPTICAL SYSTEMS FOR DETECTING BRAIN TUMORS

Carl Zeiss Meditec AG, J...

1. A microscopy system, comprising:
a surgical microscope having a first field of view configured to acquire images of a sample within the first field of view
when the sample is exposed to infrared radiation;

a confocal endomicroscope having a second field of view configured to acquire images of the sample within the second field
of view;

a navigation sub-system configured to monitor a location of the second microscope; and
a display sub-system in communication with the first microscope, the second microscope and the navigation sub-system,
wherein:
the surgical microscope has a field of view having an area of 1 cm2 or more;

the area of the field of view of the confocal endomicroscope is 1 mm2 or less; and

during operation of the microscopy system the display sub-system displays information about a relative location of one or
more images acquired using the confocal microscope relative to the field of view of the surgical microscope based on information
from the navigation sub-system.

US Pat. No. 9,254,222

MATERIAL MACHINING DEVICE AND METHOD

Carl Zeiss Meditec AG, J...

1. A machining device which machines a material by non-linear interaction of machining laser radiation with the material to
be machined, comprising:
a laser radiation source emitting said machining laser radiation, said laser radiation being configured for non-linear interaction
with the material to be machined, in a beam having a cross section and at least two regions within the cross section, including
a first region and a second region;

optics focusing the machining laser radiation at a focus for non-linear interaction between the machining laser radiation
and the material to be machined into or onto the material; and

a polarization modulator which causes the machining laser radiation to be linearly polarized, with a polarization direction
being different in the first region as compared to the second region and thus varies across the beam cross-section;

wherein, as a result of the effect of the polarization modulator on the machining laser radiation, a focus size is reduced
and laser power density and thus photon density are concentrated centrally in the beam in proximity of the focus whereby multiphoton
absorption and consequent nonlinear interaction are increased.

US Pat. No. 9,510,730

IMAGING METHOD AND APPARATUS

Optiscan Pty Ltd., Victo...

1. An imaging apparatus, comprising:
a probe, comprising:
a manually manipulable proximal portion;
a straight distal portion coupled to a distal tip, wherein the distal tip locates and defines an observational field of a
sample to be imaged confocally;

a curved portion between the proximal portion and the straight distal portion;
wherein the straight distal portion has a length of between 75 mm to 205 mm, and the curved portion provides an angle between
the proximal portion and the straight distal portion of between 120° and 150; and

a scanning mechanism that performs a raster scan on the observation field;
an optical coupler that receives light from a light source and separates the received light into a first light and a second
light;

a first connection to send the first light from the optical coupler to the probe;
a second connection to send the second light from the optical coupler to a power monitor, wherein an amount of power output
to the sample is calculated based on a ratio between power coupled by the optical coupler into the first connection and power
coupled by the optical coupler into the second connection; and

a detection unit that receives a portion of light returned confocally by the sample and collected by the probe,
wherein an image of the sample is constructed based at least in part on the portion of light detected by the detection unit
and the raster scan of the observational field.

US Pat. No. 9,498,844

DEVICE FOR MACHINING AN OBJECT BY MEANS OF LASER RADIATION

Carl Zeiss Meditec AG, J...

1. Device for treating an eye using laser radiation, comprising:
an observation device having a first objective lens that images the eye, the first objective lens being configured to image
the eye along a first optical path;

a treatment laser source that emits the laser radiation;
a laser scan device having a second objective lens that images the eye and through which the laser radiation is guided scanning
through a sector within the eye that is intended to be treated; the second objective lens being configured to image the eye
along a second optical path;

wherein
the first objective lens and the second objective lens are different from each other in a size of a segment presented for
observation in the images and/or in terms of their focal intercept, and the eye being supported to be shiftable between a
first operating mode wherein the eye is imaged through the first objective lens and a second operating mode, wherein the eye
is imaged through the second objective lens;

the device further comprising a positioning device that shifts a position of the eye relative to the first objective lens
and the second objective lens; wherein

during the first operating mode, the eye is in focus via the first objective lens, and
during the second operating mode, the eye is in focus via the second objective lens.

US Pat. No. 9,462,944

SURGICAL MICROSCOPY SYSTEM AND METHOD FOR PERFORMING EYE SURGERY

CARL ZEISS MEDITEC AG, J...

1. A method associated with introducing an intraocular lens into a lens capsule of an eye such that the intraocular lens will
have a correct orientation relative to a centre of a pupil of the eye, the method comprising:
generating a microscopic image of at least one of a portion of an iris and a portion of a limbus of the eye, using a microscopy
optics;

generating a first partial pattern superimposed with the microscopic image, such that the first partial pattern can be recognized
in the microscopic image as a straight line, and

inserting the intraocular lens into the eye and orienting the intraocular lens relative to the first partial pattern superimposed
with the microscopic image;

wherein the first partial pattern is generated such that the first partial pattern superimposed with the microscopic image
has an adjustable orientation relative to the microscopic image.

US Pat. No. 9,492,077

OPTIMIZED DEVICE FOR SWEPT SOURCE OPTICAL COHERENCE DOMAIN REFLECTOMETRY AND TOMOGRAPHY

Carl Zeiss Meditec AG, J...

1. An optimized device for swept source optical coherence domain reflectometry and tomography of structures including a human
eye, comprising:
at least one tunable light source, matched to the sought-after measurement region ZOCT, with a resonator length LR;

an interferometric measurement arrangement;
a data capturing unit for capturing light portions scattered back from a sample and a data processing unit;wherein the resonator length LR of the tunable light source is matched not only to the sought-after measurement region ZOCT, but also to the entire interferometric measurement arrangement such that disturbance points present in the interferometric
measurement arrangement cannot create disturbance signals in the sought-after measurement region ZOCT;
wherein the resonator length LR of the tunable light source is selected such that the following condition is satisfied for at least one disturbance point
m in the interfermetric measurement arrangement:

?L1,m?L2,m|?n*LR|>2*ZOCT   (2)

wherein L1 represents a path length 1,

L2 represents a path length 2,

LR represents the resonator length,

ZOCT represents the sought after measurement region,

m represents a number of all possible disturbance points, and
n represents an integer variable >0.

US Pat. No. 9,089,283

OPHTHALMOLOGIC VISUALIZATION SYSTEM

Carl Zeiss Meditec AG, J...

1. A method for determining the position and/or radius of the limbus and/or the position and/or radius of the pupil of a patient
eye, the method comprising the steps of:
obtaining an image of the patient eye;
providing a plurality of different ring-shaped comparison objects having respective radii and respective centers;
correlating said image with said plurality of said comparison objects by determining a two-dimensional brightness distribution
of respective filter responses of said comparison objects to yield an at least local maximum between said image and said comparison
objects when there is a coincidence of one of said ring-shaped comparison objects and a ring-shaped jump in brightness in
said image having the same radius and the same center;

determining said comparison objects having a local best match with said image; and,
selecting the position of the center of the comparison object having a local best match with said image as the position of
the center of the limbus and/or the position of the center of the pupil.

US Pat. No. 9,155,462

SHORT COHERENCE INTERFEROMETRY FOR MEASURING DISTANCES

Carl Zeiss Meditec AG, J...

8. A Short-coherence interferometer apparatus for measuring two axially spaced regions of a sample or an eye, comprising:
a radiation source providing measurement radiation;
a measurement beam path through which the measurement radiation falls onto the sample or the eye and which collects sample
radiation formed by measurement radiation scattered or reflected back from the sample or the eye;

a reference beam path at the end of which is arranged a reference object that reflects or scatters back radiation conducted
into reference beam path;

a coupling element, wherein the coupling element is arranged downstream of the radiation source, conducts the measurement
radiation into the measurement beam path and receives the collected sample radiation, wherein the coupling element is formed
by a polarization splitter and splits off a part of the measurement radiation coming from the radiation source as reference
radiation to provide for a time-resolved wavelength referencing, the reference radiation having a polarization state different
from the measurement radiation, and conducts the reference radiation into the reference beam path and receives the reference
radiation returning from the reference radiation beam path, wherein the coupling element further superimposes the received
sample radiation with the received reference radiation;

a tuning interferometer that receives the sample radiation and reference radiation and splits the superimposed sample radiation
and reference radiation into two beam parts, delays the two beam parts axially relatively by a path length and superimposes
the delayed two beam parts;

wherein the tuning interferometer provides for the path length of the axial relative delay to be such that the two superimposed
beam parts interfere for the axially spaced regions of the sample or the eye, and wherein,

the tuning interferometer forms single beams during the superimposition which represent quadrature components of the interfering
beam parts,

a detector device that detects the single beams and measures an interference signal with the sample radiation and the reference
radiation not interfering with each other; and

a control device for the interferometer apparatus, wherein the control device determines the quadrature components from the
single beams and deduces axial spacing between the regions from the path length and the determined quadrature components.

US Pat. No. 9,526,428

ATTACHMENT FOR A CONTACT LENS AND PRODUCTION METHOD FOR A CONTACT LENS SYSTEM

CARL ZEISS MEDITEC AG, J...

1. An attachment for a contact lens, the attachment comprising:
a first part provided to be held in position against an eye; and
a second part connected to the first part, the second part for fixing the attachment to a contact lens;
wherein the first part corresponds to a distal side of the contact lens and forms at least one of a sterile or a disinfected
bearing surface for the eye, and wherein the second part is configured to connect the attachment to the contact lens and to
bring the first part to rest against a distal side of a surface of a lens element of the contact lens, and

wherein the first part is formed to abut the contact lens with a pretensioning transferred from the second part to the first
part or with a negative pressure.

US Pat. No. 9,303,975

METHOD FOR DETERMINING THE REGISTRATION OF A STRUCTURE ON A PHOTOMASK AND APPARATUS TO PERFORM THE METHOD

Carl Zeiss SMT GmbH, Obe...

1. A method for determining a registration error of a feature on a mask, the registration error indicating a deviation of
a nominal position of the feature from its actual position on the mask the method comprising:
providing a first aerial image that was captured by a position measuring device and includes at least said feature, said feature
comprising a registration pattern or marker,

simulating, from pattern specifications of the mask, a second aerial image that includes at least said feature, taking into
account at least one effect that causes distortion of said first aerial image, and

determining the registration error of said feature as the distance of the position of said feature in said first aerial image
from the position of said feature in said second aerial image;

wherein said second aerial image is simulated, on the basis of the pattern specifications of the mask, as a transmission function
that has, at least in part, a higher resolution than said first aerial image.

US Pat. No. 9,144,375

METHOD FOR DETERMINING THE POWER OF AN INTRAOCULAR LENS

Carl Zeiss Meditec AG, J...

1. A method of determining the power of an intraocular lens implant comprising:
measuring at least one of a crystalline lens radius of curvature or crystalline lens radii of curvature with one of an optical
coherence tomography (OCT) system, a slit projection system and an Ultrasound system; and

determining the power of the intraocular lens implant based on measurements made and additional measurements including one
or more of the axial eye length, anterior cornea radius, posterior corneal radius, anterior chamber depth (ACD) and lens thickness.

US Pat. No. 9,144,517

OPHTHALMIC SURGICAL SYSTEM AND A CONTROL APPARATUS THEREFOR

Carl Zeiss Meditec AG, J...

1. A control apparatus for an ophthalmic surgical system including a handpiece for phacoemulsification of an eye lens, an
energy source configured to output ultrasound energy to the handpiece, an aspiration line configured to conduct a fluid flow
therethrough, said aspiration line being coupled to said handpiece and having a suction opening, the control apparatus comprising:
a flow determination device configured to determine an actual value of a reduced fluid flow in said aspiration line;
an occlusion determination device configured to determine whether an occlusion is present at said suction opening;
an evaluation unit configured to determine said actual value of the reduced fluid flow in said aspiration line when said occlusion
determination device has determined that an occlusion is present;

said evaluation unit being further configured to determine a first value of the ultrasound energy to be outputted to said
handpiece via said energy source in dependence upon said actual value of the reduced fluid flow; and,

a control unit configured to control said energy source to output said first value of the ultrasound energy during the occlusion,
wherein the fluid flow in said aspiration line has a nominal value when no occlusion is present; and, said evaluation unit
is configured to determine a quotient of said actual value of the reduced fluid flow divided by said nominal value of the
fluid flow in the aspiration line; and,

wherein said evaluation unit is configured to determine an integral of said quotient as a function of time over a predetermined
time duration.

US Pat. No. 9,182,540

DEVICE FOR HOMOGENIZING A LASER-BEAM PROFILE

CARL ZEISS MEDITEC AG, J...

1. A device for homogenizing a laser-beam profile and for focussing a laser spot on a target plane, the device comprising:
an optical waveguide including a fiber core,
wherein an edge of a cross-section of the fiber core comprises a straight section, the cross-section being disposed at an
end of the optical waveguide such that the laser spot comprises a corresponding straight section on the target plane.

US Pat. No. 9,296,069

APPARATUS AND METHOD FOR MATERIAL PROCESSING USING A TRANSPARENT CONTACT ELEMENT

Carl Zeiss Meditec AG, J...

1. A method of preparing an apparatus for material processing by producing optical breakthroughs in or on an object, said
apparatus comprising a variable three-dimensionally acting focus adjustment device for focusing pulsed processing laser radiation
on different locations in or on the object, wherein
the variable three-dimensionally acting focus adjustment device focuses the pulsed processing laser radiation on the different
locations in or on the object based on a first coordinate system relating to the position of the apparatus,

a contact element, which is transparent for the processing laser radiation and is to be placed on the object, is mounted to
the apparatus, said contact element having, on its side to be placed on the object, a contact surface and, located opposite
and in known geometrical relation to the contact surface, an entry surface for the processing laser radiation, the contact
surface having a known shape and being provided to deform at least a front surface of the object into the known shape, wherein
the known shape is defined in a second coordinate system relating to the contact element and wherein the first coordinate
system and the second coordinate system differ by at least an offset;

prior to processing the object, the offset is determined
by detecting the position of the contact or entry surface which constitutes a detected surface by focusing measurement laser
radiation near or on the detected surface by the variable focus adjustment device, an energy density of the focused measurement
laser radiation being too low to produce an optical breakthrough, and

determining the offset between the first coordinate system and the second coordinate system from the position of the apparatus
and the position of the detected surface.

US Pat. No. 9,195,022

STAND FOR A MEDICAL DEVICE

Carl Zeiss Meditec AG, J...

1. A stand for a medical device, the stand comprising:
a first support arm;
a second support arm configured to accommodate the medical device thereon;
a first joint connection configured to connect said second support arm to said first support arm with a first degree of freedom
of motion;

said first joint connection having a first switching device configured to be transferable into a first switching state wherein
said first degree of freedom of motion is disabled and into a second switching state wherein said first degree of freedom
of motion is enabled;

said first joint connection being configured to have a second degree of freedom of motion; and,
said second degree of freedom of motion being enabled in said first switching state of said first switching device and said
second degree of freedom of motion being disabled in said second switching state of said first switching device.

US Pat. No. 9,107,731

METHOD FOR INCREASING OCULAR DEPTH OF FIELD

CARL ZEISS MEDITEC AG, J...

1. A method of for performing a corneal ablation procedure on the eyes of a patient, the method comprising:
determining a first refractive correction for a first eye;
determining a first parameter corresponding to at least one of the first refractive correction and a condition of the patient;
selecting a first ablation profile for the first eye including a first refractive correction component and a first pre-compensating
component, the first pre-compensating component being selected based on the first parameter, the first ablation profile being
configured so as to promote a controlled induction of a higher order aberration, wherein the first pre-compensating component
limits the induction of the higher order aberration to be within a first predefined range;

determining a second refractive correction for a second eye, the second refractive correction being different than the first
refractive correction;

determining a second parameter corresponding to at least one of the second refractive correction and a condition of the patient;
selecting a second ablation profile for the second eye including a second refractive correction component and a second pre-compensating
component, the second pre-compensating component being selected based on the second parameter, the second ablation profile
being configured so as to promote a controlled induction of a higher order aberration, wherein the second pre-compensating
component limits the induction of the higher order aberration to be within a predefined range; and

ablating the cornea of the eyes with an excimer laser unit using the selected first and second ablation profiles so as to
carve a ring paracentrally in a stroma layer of the cornea;

wherein the ablation of at least one of the first and second eyes results in an epithelial lenticule forming by filling in
the carved ring in the stroma layer, the epithelial lenticule having sub-surface multi-focal properties as a result of the
pre-compensating component of the respective ablation profile; and

wherein the forming of the epithelial lenticule renders a front corneal surface to be regular and without multi-focal properties.

US Pat. No. 9,279,970

OPTICAL IMAGING SYSTEM

Carl Zeiss Meditec AG, J...

1. An optical imaging system for generating an image of an object plane, the optical imaging system defining an optical axis
and comprising:
a lens system including a main objective and a reduction optical unit arranged between said main objective and said object
plane;

said lens system being aligned along said optical axis;
said reduction optical unit including a first lens having a positive refractive power and a second lens having a negative
refractive power;

said lens system defining an object-side first main plane (H) and an image-side second main plane (H?);
said optical imaging system defining an observation beam path which is guided through said lens system so as to cause said
observation beam path to be at a distance B from the optical axis of the lens system in each of said first main plane (H)
and said second main plane (H?);

said first lens being made from a first material having a first Abbe number;
said second lens being made from a second material having a second Abbe number;
said first Abbe number being greater than said second Abbe number; and,
said lens system being configured so as to cause the following relation to be satisfied for a wavelength range ? of 480 nm???660
nm and for a main wavelength e=546 nm:

wherein:
fe =object-side focal length for the main wavelength (e) with respect to said first main plane (H);

f?=object-side focal length for the wavelength ? with respect to said first main plane (H); and,

fe?=image-side focal length for the main wavelength (e) with respect to said second main plane (H?).

US Pat. No. 9,173,559

FIXATION CONTROL DEVICE AND METHOD FOR CONTROLLING THE FIXATION OF AN EYE

Carl Zeiss Meditec AG, J...

1. A fixation monitoring device for an ophthalmological instrument, comprising:
a fixation light source configured to emit visible light;
optics configured to image the fixating light source on a fundus; and
a detector unit configured to implement spectroscopic detection of a fixation of an eye, the spectroscopic detection being
based on difference in spectral reflectivity between a fovea of the eye and a surrounding retina of the eye.

US Pat. No. 9,050,172

DEVICE AND METHOD FOR PRODUCING CONTROL DATA FOR THE SURGICAL CORRECTION OF DEFECTIVE EYE VISION

CARL ZEISS MEDITEC AG, J...

1. A device for generating control data that control a laser system for surgical correction of defective vision of an eye
of a patient, wherein:
the laser system comprises a laser for emitting laser radiation, optics for focusing the laser radiation to a focus and a
scanner for shifting a position of the focus;

the device generates the control data to be adapted to control the laser, the optics and the scanner to cut a cornea by focusing
the laser radiation into the cornea of the eye and by shifting the position of the focus within the cornea;

wherein the control data includes data to control the scanner to shift the position of the focus within the cornea;
wherein the device the control data such that the laser, the optics and the scanner, during operation under the control data,
emit and focus the laser radiation such that a volume in the cornea is isolated, the removal of which volume from the cornea
effects a desired correction of the defective vision; and

to determine the control data, the device is configured to calculate a radius of curvature RCV* of the cornea reduced by the volume;

wherein the radius of curvature RCV* is locally varying and satisfies the following equation:

RCV*(r,?)=1/((1/RCV(r,?)+BCOR(r,?)/(nc?1))+F,
wherein RCV(r,?) is the local radius of curvature of the cornea before the volume is removed, nc is the refractive index of the material
of the cornea, F is a coefficient, and BCOR(r,?) is the local change in optical refraction power in a plane lying in the vertex of the cornea and required for the desired
correction of the defective vision; and

wherein there are at least two radii, r1 and r2, for which BCOR(r=r1,?)?BCOR(r=r2,?) holds true.

US Pat. No. 9,377,293

IMAGING SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A system comprising an OCT system, the OCT system comprising:
an interferometer providing a measuring arm extending towards an object to be measured, a reference arm, and including an
OCT measuring light source, at least one beam splitter and a detection system configured to detect OCT measuring light returned
from the measuring arm and superimposed with OCT measuring light returned from the reference arm,

wherein the OCT system is switchable to a first operation mode and a second operation mode;
wherein in the first operation mode, a spectral width of the OCT measuring light, emitted from the OCT measuring light source,
is smaller or at least two times smaller than in the second operation mode; and

wherein in the second operation mode, a lateral width of a beam waist of a beam of the OCT measuring light is smaller or at
least two times smaller than in the first operation mode.

US Pat. No. 9,216,301

BALLOON CATHETER AND APPLICATOR WITH BALLOON CATHETER

CARL ZEISS MEDITEC AG, J...

1. A method of controlling a balloon catheter with respect to its shape and position in a tissue to be treated prior to an
irradiation, the method comprising the steps of:
placing a balloon catheter in a folded configuration in the tissue to be treated, wherein the balloon catheter is part of
an applicator, said balloon catheter comprising a catheter shaft for introducing a probe, a first, outer balloon formed of
a flexible, non-extendible material, a second, inner balloon, disposed inside the outer balloon, said inner balloon being
formed of a flexible, extendible material, said inner balloon having an inner space, the inner space connecting with a channel
for connection to a medium inlet, and an intermediate space between the outer balloon and the inner balloon, said intermediate
space connecting via a channel for connection to a medium storage unit, whereby the intermediate space, the connection channel
and the medium storage unit form a closed system wherein no medium is introduced to the closed system from outside the closed
system and no medium is withdrawn from the closed system and whereby at least temporarily a defined medium volume, by which
the position of the balloon catheter can be examined precisely, is disposed in the intermediate space;

subsequently, filling the inner balloon via the connection channel from the medium inlet up to a standard state, wherein,
in the standard state, the inner balloon has a filling volume V2, which is smaller than a filling volume V1 of the outer balloon and displacing medium, which is found in the intermediate space by the filling of the inner balloon
to the standard state such that a distance between the outer balloon and the inner balloon is maintained in the standard state;

examining the position and shape of the balloon catheter by use of imaging methods; and
correcting the position and shape of the balloon catheter if necessary.

US Pat. No. 9,108,046

METHOD OF GENERATING AND/OR PROVIDING DATA FOR TISSUE TREATMENT

CARL ZEISS MEDITEC AG, J...

1. Method for generating or providing data for a tissue treatment by means of a low-energy irradiation device, wherein the
low-energy irradiation device has an irradiation source for generating soft radiation, preferably of a radiation with a spectrum
of 0 to a maximal ray energy of 100 keV, in particular a radiation with a spectrum of 0 to a maximal radiation energy of 50
keV and an emitting device for emitting the irradiation to a tissue which is to be irradiated, characterized by the following
steps:
physical data of the irradiation source is determined directly upon leaving the emitting device;
constitutional data of the tissue is determined;
physical property data of the determined tissue is determined in connection with the irradiation of the irradiation source;
data for the tissue treatment is generated from the determined data or the determined data is provided for generating data
for the tissue treatment.

US Pat. No. 9,352,415

METHOD FOR GENERATING AN ABLATION PROGRAM, METHOD FOR ABLATING A BODY AND MEANS FOR CARRYING OUT SAID METHOD

Carl Zeiss Meditec AG, J...

1. A computer implemented method of generating an ablation control program to control emission of a pulsed laser energy beam
from a laser to accomplish ablation of material from a surface of a body by application of the pulsed laser energy, comprising:
predetermining a predetermined desired ablation profile which indicates ablation depth as a function of a location on the
surface of the body or which indicates ablation depth as a function of a direction of the laser beam with respect to the body;

modifying the predetermined desired ablation profile as a function of a beam profile of the laser beam, the beam profile being
a course of intensity or of surface area related energy or fluence of a pulse of laser energy over a beam cross section near
the surface of the body, and also as a function of an inclination of the surface of the body to be ablated to create a pre-compensated
desired ablation profile that is based on the energy distribution across the beam profile and the inclination of the surface
at a respective target location on the surface; and

then, generating the ablation control program based on the pre-compensated desired ablation profile following the modification
of the predetermined desired ablation profile;

wherein the ablation control program comprises at least one of a series of target locations related to the surface of the
body or target directions onto or into which the pulsed laser energy beam is to be applied.

US Pat. No. 9,232,983

METHOD AND APPARATUS FOR DETERMINING THE ILLUMINATION BEAM DOSE IN SURGICAL FIELD ILLUMINATION

Carl Zeiss Meditec AG, J...

1. A method for determining a simulation-based illumination beam dose of light that will be emitted onto a surgical region
by a light emitting illumination apparatus during a course of a surgery, comprising the following steps:
registering setting parameter values including characteristics of the illumination apparatus and at least one of: a presence
or absence of a filter apparatus, a presence or absence of a stop, ambient light conditions and characteristics of a surgical
site;

selecting, from a storage, dose simulation characteristics assigned to each of the registered setting parameters;
calculating dose simulation values (300) taking into account the registered setting parameters and the assigned dose simulation characteristics selected from the
storage for each of the registered setting parameters; and
calculating the simulation-based illumination beam dose taking into account the calculated dose simulation values, wherein
the simulation-based illumination beam dose of light is emitted onto an eye by the light emitting illumination apparatus.

US Pat. No. 9,179,839

METHOD FOR DETERMINING AT LEAST ONE DIAGNOSIS OR RISK ASSESSMENT PARAMETER RELATED TO AMD

Carl Zeiss Meditec AG, J...

1. A method for determining at least one parameter for diagnosing or assessing the risk of a disease, including the risk of
developing the disease of Aging related Macular Degeneration (AMD), the method comprising:
determining a distribution of the macular pigment MP of an eye;
determining at least one area whose bordering line corresponds to a constant optical density MPD and/or concentration MPC
of the macular pigment by an analysis unit from the distribution of the macular pigment MP; and

subjecting the at least one area to a quantitative shape description by determining a fractal dimension FD of the bordering
line as a standardized value FDnorm, wherein the fractal dimensions FD or FDnorm are indicative of a disease-related change
when a predetermined limit value is exceeded; and

deriving at least one parameter DP which is suitable for diagnosing a disease and/or the risk of developing the disease of
AMD and/or monitoring its treatment from the quantitative shape description of the bordering line of the area.

US Pat. No. 9,044,164

DEVICE FOR SWEPT SOURCE OPTICAL COHERENCE DOMAIN REFLECTOMETRY

Carl Zeiss Meditec AG, J...

1. A device for swept source optical coherence domain reflectometry (SS OCDR) on a movable sample, for the purpose of obtaining
A-scans, comprising:
a tunable laser light source;
at least one receiver for light backscattered from the sample, wherein the sample is illuminated on the sample surface with
a measurement beam of diameter D;

wherein the light source has a line width of ?k<168 m?1; and

further wherein tuning of the light source is performed in a time ? about a centroid wave number k0 and wherein a photon flux of 3*108 to 3*1013 is directed onto the eye during tuning of the time ? of the light source.

US Pat. No. 9,271,829

METHOD FOR THE PRE-OPERATIVE SELECTION OF AN INTRAOCULAR LENS TO BE IMPLANTED IN AN EYE

Carl Zeiss Meditec AG, J...

1. A method for pre-operative selection of an intraocular lens (IOL) to be implanted in an eye, based on an eye model having
the individual biometric parameters of the eye, comprising:
selecting potentially suitable IOLs using optical parameters thereof selected from a group consisting of optical power, asphericity,
and toricity, and calculating a residual refraction by application of ray tracing for the potentially suitable IOLs,

using one of various metrics for calculating the residual refraction and
for improving the selection, including in the calculation at least one additional parameter that takes into account pre-operative
features of the eye, post-operative effects of the selected IOL or surgical technique used.

US Pat. No. 9,456,746

SYSTEMS AND METHODS FOR BROAD LINE FUNDUS IMAGING

CARL ZEISS MEDITEC, INC.,...

1. A method for collecting reduced artifact images of the fundus of the eye with a broad line fundus imaging (BLFI) system,
said method comprising;
scanning a beam of radiation over a range of transverse locations on the fundus of the eye, wherein the beam of radiation
illuminates with a defined width on a region of the sample;

collecting light returning from the eye in response to the illumination, wherein the region on the sample from which light
is collected corresponds to the illumination area and has a defined collection width, wherein the width of the illumination
light and/or the width of the collection area is adjusted during the scanning steps;

generating an image from the collected light; and
displaying or storing the image.

US Pat. No. 9,084,666

TREATMENT DEVICE FOR SURGICALLY CORRECTING AMETROPIA OF AN EYE AND METHOD FOR CREATING CONTROL DATA THEREFORE

Carl Zeiss Meditec AG, J...

1. A treatment apparatus for surgical correction of hyperopia in an eye, the treatment apparatus comprising:
a laser device including a laser and scanners, the scanners each comprising mirrors, optics or a combination of mirrors and
optics, which is controlled by a control device and which separates corneal tissue by applying laser radiation;

the control device being programmed with an algorithm that controls the laser device including the laser and the scanners
to emit the laser radiation into the cornea at a focus positioned by operation of the laser and the scanners wherein a lenticular
volume is isolated in the cornea, the lenticular volume being structured such that removal of the lenticular volume effects
a desired correction of hyperopia;

the control device being programmed with an algorithm that controls the laser and the scanners to define the lenticular volume
to have a posterior face and an anterior face and edges that are connected via an annular edge face, the edge face having,
in projection along an optical axis of the eye, a first ring width that is greater than a second ring width that would be
created in the projection along the optical axis of the eye by a straight line extending perpendicularly from an edge of the
posterior or the anterior face to the other of the posterior or the anterior face or to an imaginary continuation of the posterior
face or the anterior face.

US Pat. No. 9,351,644

MEDICAL SYSTEMS AND METHODS

Carl Zeiss Meditec AG, J...

1. A method, comprising:
recording a first plurality of images of a plurality of points of at least one blood vessel, each of the first plurality of
images comprising fluorescent light intensity information at each of the plurality of points of the at least one blood vessel;

for each of the plurality of points of the at least one blood vessel, analyzing the first plurality of recorded images to
determine a fluorescent light intensity at the point over a first period of time; and

for each of the plurality of points of the at least one blood vessel, displaying a first image that represents the fluorescent
light intensity at the point over the first period of time.

US Pat. No. 9,504,607

METHOD AND DEVICE FOR STABILIZING THE CORNEA

Carl Zeiss Meditec AG, J...

1. A method for stabilizing a cornea of an eye, comprising:
irradiating the cornea by laser light in order to crosslink collagen fibers of the cornea;
wherein the cornea is locally irradiated successively at different sites in such a way that the collagen fibers are crosslinked
at the irradiated sites, and

wherein the collagen fibers are ionized in each instance through photoabsorption of a plurality of photons each having an
energy below the ionizing energy of a respective molecule, whereupon a direct covalent bond is formed between the collagen
fibers.

US Pat. No. 9,452,299

FLEXIBLE APPLICATOR FOR RADIATION THERAPY

Carl Zeiss Meditec AG, J...

1. An applicator, comprising:
a substantially cylindrical main body configured to hold a radiation source, an interior of the main body having a cavity
which extends along a main axis of the main body;

a substantially cylindrical absorption body movably connected to the main body; and
a pivot joint configured to enable an axis of rotation of the absorption body, wherein:
the absorption body is configured so that, when the main body is holding the radiation source and the radiation source is
emitting radiation, the absorption body influences the radiation to define a preferred radiation direction;

the main body and the absorption body are arranged in succession in a longitudinal direction;
in a plane, an end of the cylindrical main body abuts against an end of the absorption body;
the plane is angled relative to the main axis of the main body;
the absorption body is rotatably connected to the main body;
the axis of rotation of the absorption body is angled with respect to the main axis of the main body so that the preferred
radiation direction is tiltable into a plurality of different positions relative to the main axis of the main body.

US Pat. No. 9,320,436

METHOD AND DEVICE FOR DETECTING DEPOSITS IN THE EYE

Carl Zeiss Meditec AG, J...

1. A method for detecting ?-amyloid deposits in a living retina of an eye, comprising:
imaging the living retina at a local resolution; and
selecting the local resolution such that it is better than 10 ?m;
evaluating images from the imaging to discern the location of the deposits within the retina to distinguish Alzheimer's disease
from aging related macular degeneration; and

basing differentiation of Alzheimer's disease from aging related macular degeneration on distinguishing an occurrence of ?-amyloid
in a retinal nerve fiber layer or a ganglion cell layer of the living retina from the occurrence of ?-amyloid in drusen, wherein
?-amyloid located in the retinal nerve fiber layer or the ganglion cell layer of the living retina is considered indicative
of Alzheimer's disease and wherein ?-amyloid located in the drusen is considered indicative of aging related macular degeneration.

US Pat. No. 9,078,732

OPHTHALMOLOGIC LASER SYSTEM

Carl Zeiss Meditec AG, J...

1. An ophthalmological laser system for photodisruptive irradiation of ocular tissue, the ocular tissues including a crystalline
lens or a cornea, the ophthalmological laser system comprising:
an ultra-short pulse laser, the ultra-short pulse laser emitting radiation which is focusable as illumination light via an
illumination beam path in an examination region including at least one of the crystalline lens and the cornea, the illumination
beam path including a scanner unit and focusing optics;

a control unit programmed to execute the following:
determining irradiation control data for photodisruptions at a plurality of irradiation points in an interior of the ocular
tissue to create at least one predetermined target incision in such a way that the irradiation points are distributed three-dimensionally
and non-equidistantly; and

irradiating the ocular tissue according to the determined irradiation control data;
wherein the control unit is further programmed to execute the following to determine the irradiation control data:
a) determining preliminary irradiation control data in accordance with the at least one target incision;
b) predicting an interference pattern resulting from the preliminary irradiation control data with transmitted light;
c) determining an intensity of diffraction light of the first or higher order of the predicted interference pattern;
d) comparing the determined intensity with a predetermined intensity threshold; and
e) repetition of a) to d) if the determined intensity is greater than the intensity threshold, wherein in step a) the preliminary
irradiation control data are modified or other preliminary irradiation control data are determined.

US Pat. No. 9,265,658

CONTACT ELEMENT FOR LASER MACHINING

Carl Zeiss Meditec AG, J...

1. An optical contact element for coupling a laser processing device to an object to be processed, wherein
the laser processing device focuses a scanned laser beam through a surface of the object into a certain region of the object
and

the contact element comprises a plano-concave base body a concave surface of which provides an exit side and a planar surface
of which provides an entrance side, and a diffractive optical element being formed on or at a surface of the entrance side,
the exit side imparting a defined surface curvature to the surface of the object upon contact therewith, wherein

the entrance side cross section is larger than a cross section of the scanned laser beam which is scanned over the entrance
side, and

the diffractive optical element being configured to reduce the angle of incidence of the laser radiation on an interface between
the surface of the object and the exit side of the contact element peripheral to an optical axis, the angle of incidence being
measured from a normal to the defined surface curvature on the surface of the object across the exit side that imparts the
defined surface curvature to the surface of the object.

US Pat. No. 9,351,878

SAFETY MECHANISM FOR LASER TREATMENT APPARATUS

Carl Zeiss Meditec AG, J...

1. A laser treatment apparatus for ophthalmic surgery, comprising:
a headrest for a patient;
a housing;
a contact glass, which can be placed onto an eye of the patient and through which a treatment laser beam is incident; and
a safety mechanism which, when actuated, moves the headrest and the contact glass apart, the safety mechanism being configured
such that actuation occurs when a force applied by the eye to the contact glass exceeding a predefined limit value of force
is directed onto the contact glass in a direction counter to the direction of incidence of the laser beam;

wherein the safety mechanism is further configured to actuate separating movement only when the force applied by the eye exceeds
the limit value of force and wherein the safety mechanism fixes the headrest and the contact glass relative to each other
if said force applied by the eye is below the limit value of force and further wherein the safety mechanism comprises a stop
of the housing and a holding element to which the contact glass is mounted, wherein the holding element is pressed against
the stop of the housing by a force defining the limit value of force.

US Pat. No. 9,364,144

METHOD AND DEVICE FOR RECORDING AND DISPLAYING AN OCT WHOLE-EYE SCAN

Carl Zeiss Meditec AG, J...

1. A method for recording and displaying an OCT whole-eye scan based on swept source optical coherence reflectometry (SS OCDR),
comprising:
illuminating the eye with a laser beam of a tunable laser light source having a measurement range corresponding to an eye
length of an eye;

displacing a focus of the laser beam in the eye laterally and/or axially by an adjustment mechanism;
capturing the light fractions backscattered from the eye via an interferometer with a scan unit;
converting the light fractions to data by a data acquisition unit;
transferring the data to a data processing unit;
wherein the data processing unit combines an OCT whole-eye scan with at least one overlapping tomographic part-eye or whole-eye
scan using reference information to register the first whole-eye scan with further part-eye or whole-eye scans, and evaluates
and/or displays the combined whole-eye scan on a user interface.

US Pat. No. 9,261,697

SCANNING DEVICE

Carl Zeiss Meditec AG, J...

1. A surgical laser system including a scanning device for focusing a luminous beam into a selected range of an eye to be
treated, the surgical laser system comprising:
a femtosecond surgical laser source that produces the luminous beam, the femtosecond surgical laser source being structured
to produce photo disruptions within tissues of an eye to be treated upon focal application of the luminous beam to the tissues;

entrance optics following the femtosecond surgical laser source into which the luminous beam first enters comprising at least
a first optical element, the first optical element comprising a lens or non planar mirror;

focusing optics by which the luminous beam emitted from the entrance optics is focused on the eye to be treated;
a deflecting device arranged between the first optical element and the focusing optics to divert a focus position of the luminous
beam that leaves the first optical element in a lateral direction, the deflecting device comprising a first movable reflective
element movable about a first axis configured to deflect the luminous beam in an X direction and a second movable reflective
element movable about a second axis that is substantially orthogonal to the first axis configured to deflect the luminous
beam in a Y direction;

a beam splitter, located between the deflecting device and the focusing optics at a location where the luminous beam exhibits
substantially parallel light rays, that directs observation beams from points in the cornea in a direction of a tube with
an eye piece or an objective with a camera configured to permit monitoring of the cornea during application of the luminous
beam to the cornea directly along an axis of the luminous beam as the luminous beam is applied to the cornea; and

in which the entrance optics and focusing optics are chromatically corrected over a spectral range of selected femtosecond
pulses, so that the femtosecond pulses can be focused with dispersion induced temporal broadening of less than about thirty
percent.

US Pat. No. 9,161,687

DEVICE FOR INTERFEROMETRICALLY MEASURING THE EYE LENGTH AND THE ANTERIOR EYE SEGMENT

Carl Zeiss Meditec AG, J...

1. A device for interferometrically measuring the eye length and the anterior portion of the eye, comprising:
an illumination source producing illumination light;
two interferometric measuring systems, at least one of the two interferometric measuring systems comprising a delay line as
an external reference;

various optical imaging systems; and
a control and evaluation unit;
wherein the illumination source has high spatial coherence and low temporal coherence and an optical imaging system is situated
in front of the eye such that the illumination light strikes the eye as an approximately collimated beam,

wherein the two interferometric measuring systems comprise a first, diffraction-limited interferometric measuring system that
measures the eye length and a second, non-diffraction-limited interferometric measuring system that measures the anterior
portion of the eye, and a beam splitter that couples an illumination path and a detection beam and which is configured such
that light reflected from various areas of the eye is split into the two interferometric measuring systems.

US Pat. No. 9,291,760

COUPLING-IN APPARATUS FOR COUPLING LIGHT FROM A LIGHT-EMITTING DIODE INTO A FIBER ENTRY END AND LIGHT-SOURCE ARRANGEMENT FITTED THEREWITH

Carl Zeiss Meditec AG, J...

1. A coupling-in apparatus for coupling light from a light-emitting diode into a fiber entry end of at least one optical fiber,
wherein the coupling-in apparatus comprises:
at least one light-guide element including a rigid main body in the form of a rod, the at least one light-guide element configured
to couple light from the light-emitting diode into the fiber entry end of the at least one optical fiber, the at least one
light-guide element has a specific transmission property, has an entry end that faces the light-emitting diode, and an exit
end that faces the fiber entry end, and

a changing device on which the light-guide element is arranged, wherein the changing device is configured to be arranged and
moved into a first position with respect to the light-emitting diode and the fiber entry end such that the entry end of the
light-guide element lies opposite the light-emitting diode and the exit end of the light-guide element lies opposite the fiber
entry end.

US Pat. No. 9,149,652

METHOD FOR TRANSPORTING RADIATION, APPLICATOR AS WELL AS RADIATION THERAPY DEVICE

CARL ZEISS MEDITEC AG, J...

1. A method for transporting radiation to a body region, said method comprising:
forming a canal up to the body region, wherein said forming step comprises drilling or tissue punching the canal, the canal
having a canal diameter, the canal diameter being substantially uniform,

then, introducing an applicator which is fitted to the diameter of the canal into the canal in order to guide a probe tip
or a radiation source unit, said applicator being shaped for use with a radiation therapy device for producing a defined radiation
dose for irradiating the body region, wherein the applicator comprises a base body, the base body comprising a foot region
for uptake of at least one component of a radiation therapy device and a cylindrical guide region connected thereto for uptake
of a probe tip or a radiation source unit of a radiation therapy device, a distal end of the cylindrical guide region constituting
a head region, said head region being a free end of the cylindrical guide region, wherein the cylindrical guide region of
the applicator has an outer diameter which is fitted to the canal diameter, and

introducing the probe tip or the radiation source unit into the applicator.

US Pat. No. 9,285,576

STEREOSCOPIC MICROSCOPE

CARL ZEISS MEDITEC AG, J...

1. A stereoscopic microscope having a first pair of stereoscopic optical paths allocated to a co-observer, and a second pair
of stereoscopic optical paths allocated to a main observer, comprising:
an objective system commonly traversed by each optical path of the first and second pairs of stereoscopic optical paths;
a first focusing lens having a first optical refractive power and a second focusing lens having a second optical refractive
power, the first and second focusing lenses, respectively, being separate elements commonly traversed by only the first pair
of stereoscopic optical paths; and

at least one actuator, the actuator being adapted to shift at least one of the focusing lenses along the optical axes of the
first pair of stereoscopic optical paths for varying a working distance of the stereoscopic microscope;

wherein the first focusing lens is immediately neighboring the objective system along the optical axes of the first pair of
stereoscopic optical paths, and

wherein the first optical refractive power of the first focusing lens and the second optical refractive power of the second
focusing lens have different signs.

US Pat. No. 9,486,359

OPHTHALMIC SURGICAL SYSTEM AND CONTROL ARRANGEMENT THEREFOR

Carl Zeiss Meditec AG, J...

1. A control arrangement for an ophthalmic surgical system for phacoemulsification of an eye lens, the ophthalmic surgical
system including a phacoemulsification handpiece having a needle; and, an ultrasound energy source for supplying ultrasound
energy to said phacoemulsification handpiece; said control arrangement comprising:
an optical system for generating an image of an object region wherein at least a part of said eye lens and a part of said
needle are arranged;

an image evaluation unit configured to evaluate said image so as to determine at least one evaluation variable dependent upon
a characteristic of a particle of said eye lens generated by phacoemulsification or a relation of said particle to its surroundings;

a control unit operatively connected to said image evaluation unit for receiving said evaluation variable;
said control unit being configured to generate a control variable in dependence upon said evaluation variable and, with said
control variable, control an absolute value of said ultrasound energy for the phacoemulsification of said eye lens;

said evaluation variable being a geometric measurement variable of said particle of said eye lens to be emulsified; and,
said geometric measurement variable being the area or the circumference or the volume of the particle to be emulsified in
said image,

wherein said optical system includes a light microscope and/or an optical coherence tomography (OCT) system.

US Pat. No. 9,474,647

EYE SURGERY REFRACTION CORRECTION

CARL ZEISS MEDITEC AG, J...

1. A planning device for producing control data for a treatment device for eye surgery which produces at least one cutting
surface in a cornea of an eye using a laser device to produce a lenticule for removal from the eye, the planning device comprising:
a calculation module for establishing the at least one cutting surface defining the lenticule, the calculation module being
configured to:

establish the at least one cutting surface based on data of a desired refraction correction of the eye,
produce a control data set for actuating the laser device for the at least one cutting surface, and
determine the at least one cutting surface in such a way that it comprises a plurality of zones,
wherein the plurality of zones comprises:
a first correction zone having a first depth and a first curvature, the first curvature being selected to achieve a first
refraction correction over the first correction zone, and a second correction zone having a second depth and a second curvature,
the second curvature being selected to achieve a second refraction correction over the second correction zone,

wherein the first and second depths differ from each other, and
wherein the first and second refraction corrections are equal to each other and to the desired refraction correction of the
eye.

US Pat. No. 9,304,306

OPTICAL IMAGING SYSTEM

Carl Zeiss Meditec AG, J...

1. An optical imaging system for generating an image of an object plane, the optical imaging system defining an optical axis
and comprising:
a lens system including a main objective and a reduction optical unit arranged between said main objective and the object
plane;

said lens system being aligned along the optical axis;
said reduction optical unit including a first composite element having a positive refractive power and a second composite
element having a negative refractive power;

said first composite element being disposed between said main objective and the second composite element;
said first composite element includes a first lens and a second lens;
said second composite element includes a third lens and a fourth lens;
said lens system defining an object-side first main plane (H) and an image-side second main plane (H?);
the optical imaging system defining an observation beam path which is guided through the lens system so as to cause said observation
beam path to be at a distance B from the optical axis of the lens system in each of said first main plane (H) and said second
main plane (H?);

said first lens having a lower refractive power than said second lens and said third lens having a lower refractive power
than said fourth lens;

said first lens being manufactured from a first material having a first Abbe number; said second lens being manufactured from
a second material having a second Abbe number; said third lens being manufactured from a third material having a third Abbe
number; and, said fourth lens being manufactured from a fourth material having a fourth Abbe number;

said first Abbe number being less than said second Abbe number and said third Abbe number being less than said fourth Abbe
number; and,

said lens system being configured so as to cause the following relation to be satisfied for a wavelength range (?) of 480
nm???660 nm and for a main wavelength e=546 nm:

wherein:
fe=object-side focal length for the main wavelength (e) with respect to said first main plane (H);

f?=object-side focal length for the wavelength (?) with respect to said first main plane (H);

fe?=image-side focal length for the main wavelength (e) with respect to the second main plane (H?).

US Pat. No. 9,532,710

FLEXIBLE, MULTIMODAL RETINA IMAGE RECORDING SYSTEM AND MEASUREMENT SYSTEM

Carl Zeiss Meditec AG, J...

4. A method of focusing individual modalities of a multimodal retinal image recording system, comprising:
focusing a focusing marker and a focusing objective based on IR live recordings of the focusing marker;
storing an axial position of the focusing objective as reference position;
adjusting the axial position of the focusing objective by a fixedly predetermined offset in relation to the reference position
to focus for an OCT recording mode;

switching a mirror from IR live mode to OCT recording mode;
performing an OCT recording;
adjusting the axial position of the focusing objective by a further fixedly predetermined offset relative to the reference
position to focus for a 2D imaging mode;

switching the mirror from OCT mode to 2D imaging mode;
making a 2D imaging recording.

US Pat. No. 9,408,747

PLANNING SYSTEM AND PROCEDURE FOR EYE SURGERY

CARL ZEISS MEDITEC AG, J...

1. A planning system for generating control data for a treatment device for eye surgery that creates at least two incision
surfaces in the cornea using a laser apparatus, the planning system comprising:
a computation device configured to specify the cornea incision surfaces based on data of a refractive correction, the cornea
incision surfaces including an access incision for removing a lenticule and a cap incision, the access incision having a smaller
diameter than the cap incision and being positioned within a periphery of the cap incision, and to generate a control data
record for the cornea incision surfaces for purposes of controlling the laser apparatus.

US Pat. No. 9,351,634

METHOD FOR AUTOMATIC OPTIMIZATION OF THE CALCULATION OF AN INTRAOCULAR LENS TO BE IMPLANTED

Carl Zeiss Meditec AG, J...

1. A method for automatically optimizing the calculation of an IOL to be implanted, comprising:
a) determining pre-surgically at least corneal topography, eye length, and anterior chamber depth;
b) calculating by application of ray tracing of the IOL to be implanted;
c) post-surgically determining, after the cataract surgery has been performed, at least the corneal topography, the eye length,
the anterior chamber depth, and an objective, wave front-based residual refraction;

d) utilizing the pre-surgically and post-surgically determined measured values in two additional method steps:
e) automatically optimizing the surgically induced astigmatism, and,
f) automatically optimizing the anatomical, post-surgical lens position.

US Pat. No. 9,526,410

EYE SURGERY SYSTEM AND METHOD OF INSERTING AN INTRAOCULAR LENS

CARL ZEISS MEDITEC AG, J...

1. An eye surgery system, comprising:
a user interface;
a measuring system including one or more measuring devices, the measuring system configured to determine at least preoperative
values and intraoperative values of an eye;

one or more computers configured to execute a first computing module configured to determine a first value based on preoperative
values, wherein the first value represents a property of an intraocular lens;

the one or more computers configured to execute a second computing module configured to determine a second value based on
a simulation performed on an eye model, wherein the second value represents a postoperative visual defect of an eye, and wherein
the eye model includes plural parameters; and

a controller configured
to trigger the measuring system to determine preoperative values including a value representing a curvature of a cornea of
the eye,

to trigger the first computing module to determine the first value representing the property of the intraocular lens, based
on the preoperative values,

to trigger the user interface to display the first value representing the property of the intraocular lens,
to trigger the measuring system to determine intraoperative values,
to trigger the second computing module to determine the second value representing the postoperative visual defect of the eye,
wherein the preoperative values of the eye are assigned to a first subset of the plural parameters and wherein the intraoperative
values of the eye are assigned to a second subset of the plural parameters of the eye model, and

to trigger the user interface to display the second value representing the postoperative visual defect of the eye.

US Pat. No. 9,504,381

SYSTEM AND METHOD FOR THE NON-CONTACTING MEASUREMENTS OF THE EYE

Carl Zeiss Meditec AG, J...

1. An apparatus for non-contacting measurement of axial length and anterior chamber depth of an eye, the apparatus comprising:
an interferometer device for measuring the axial length of the eye, wherein the interferometer device comprises at least one
adjustable element for adjusting a path length difference and a detector for detecting interfering radiation,

a light path having a source of slit-shaped illumination radiated on the eye at a non-zero angle to an observation axis measured
at the eye, and the light path comprising slit imaging optics and at least one light source;

a receiver separate from the detector which detects scatter images coming from structures of the eye and which is located
substantially on the observation axis, the receiver, the slit shaped illumination and the imaging optics being angularly fixed
relative to each other; and

a signal processing device which controls the interferometer device, receives signals from the detector and calculates the
axial length and which receives signals from the receiver and processes the signals to determine distances between portions
of the scatter images that represent the structures of the eye and calculates anterior chamber depth from the distances.

US Pat. No. 9,237,965

RE-TREATMENT FOR OPHTHALMIC CORRECTION OF REFRACTION

Carl Zeiss Meditec AG, J...

1. A method of refraction-correcting ophthalmic surgery, said method comprising:
accessing corneal data including information on pre-operative cuts generated in a previous ophthalmic operation;
defining a corneal cut surface to thereby confine a corneal volume to be removed for refractive correction on the basis of
the corneal data;

generating a control dataset for the corneal cut surface;
transmitting the control data to a treatment apparatus that comprises a laser device; and
generating the cut surface by controlling the laser device using the control dataset.

US Pat. No. 9,223,148

MULTIFOCAL LENS

Carl Zeiss Meditec AG, J...

1. A multifocal lens having a number n>2 of principal powers and comprising:
a maximum of n?1 lens portions including a first lens portion having at least one first annular zone and a second lens portion
having at least one second annular zone;

said annular zones having respective main sub-zones exhibiting refractive powers and respective phase sub-zones exhibiting
refractive powers and providing phase shifts;

a combination of said main sub-zones forming a diffractive lens portion providing at least one diffractive power, said diffractive
power being one of the principle powers of said multifocal lens;

said lens portions differing in at least one optical parameter from each other and being combined to form said n principal
powers; and,

an averaged refractive power of said first annular zone of the first lens portion being equal to an averaged refractive power
of said second annular zone of the second lens portion.

US Pat. No. 9,095,255

METHOD AND DEVICE FOR LOCATING FUNCTION-SUPPORTING TISSUE AREAS IN A TISSUE REGION

Carl Zeiss Meditec AG, (...

1. A method for locating functional tissue areas in a tissue region, the method comprising the steps of:
illuminating the tissue region by providing a measurement illumination with at least one wavelength at which a stimulation
of the functional tissue areas leads to a change in at least one optical property of a reflected measurement illumination
as compared to the measurement illumination;

recording at least one image of the tissue region without stimulation while the tissue region is illuminated with the measurement
illumination;

recording at least one image of the tissue region without stimulation while the tissue region is not illuminated with the
measurement illumination;

forming a comparison image of the tissue region from the difference of the at least one image of the tissue region recorded
without stimulation while the tissue region is illuminated with the measurement illumination and the at least one image of
the tissue region recorded without stimulation while the tissue region is not illuminated with the measurement illumination,
thereby eliminating or reducing influences of surroundings from the comparison image;

recording at least one image of the tissue region during stimulation while the tissue region is illuminated with the measurement
illumination;

recording at least one image of the tissue region during stimulation while the tissue region is not illuminated with the measurement
illumination;

forming a stimulation image of the tissue region from a difference between
a) the at least one image of the tissue region recorded during stimulation while the tissue region is illuminated with the
measurement illumination, and

b) the at least one image of the tissue region recorded during stimulation while the tissue region is not illuminated with
measurement illumination, thereby eliminating or reducing influences of the surroundings from the stimulation image; and

locating the functional tissue areas in the tissue region on the basis of the change in the at least one optical property
of the reflected measurement illumination as compared to the original measurement illumination by determining a difference
between the stimulation image of the tissue region and the comparison image of the tissue region.

US Pat. No. 9,427,822

LASER TREATMENT DEVICE

Carl Zeiss Meditec AG, J...

1. An adapter for coupling an eye to be treated in ophthalmic surgery with a laser treatment device comprising a scanning
device for scanning a laser beam, the adapter comprising:
an adapter input side, being fixable relative to the laser treatment device via a locking mechanism;
an adapter beam path,
a scanned region being part of the adapter input side, wherein the laser beam having been supplied to the scanned region is
transmitted along the adapter beam path to the eye, wherein the adapter beam path starts at the scanned region and the laser
beam passes through the scanned region and along the adapter beam path when being scanned during laser treatment; and

a reference structure, the reference structure being located in the adapter beam path such that the reference structure can
be illuminated by laser radiation being scanned over the scanned region, wherein the reference structure is adapted to absorb
or reflect the laser radiation to make the reference structure optically detectable;

wherein the reference structure is located in a known position relative to the adapter and scanning of the reference structure
by the scanned laser beam allows the laser treatment device to detect the position of the adapter.

US Pat. No. 9,180,052

METHOD AND DEVICE FOR NON-INVASIVE TEMPERATURE DETERMINATION IN BIOLOGICAL TISSUE TREATED WITH TREATMENT RADIATION

Carl Zeiss Meditec AG, J...

1. A method for a non-invasive temperature determination on an ocular fundus, that is treated with a treatment radiation,
the method comprising;
providing a radiation source that selectively emits measuring radiation pulses and treatment radiation pulses;
providing a detector;
applying the measuring radiation pulses generated by the radiation source to the ocular fundus to produce a reaction that
depends on treatment temperature

recording the reaction by use of the detector; and
applying the measuring radiation pulses and the treatment radiation pulses sequentially to the ocular fundus to be treated
from the radiation source.

US Pat. No. 9,174,069

BALLOON CATHETER AND APPLICATOR WITH BALLOON CATHETER

CARL ZEISS MEDITEC AG, J...

1. An applicator comprising a balloon catheter, said balloon catheter comprising a catheter shaft for introducing a probe,
said balloon catheter having an outer balloon made of a flexible, non-extendible material, an inner balloon disposed inside
the outer balloon, said inner balloon being made of a flexible, extendible material, said inner balloon having an inner space,
the inner space connecting with a channel for connection to a medium inlet, said applicator having a medium storage unit,
wherein an intermediate space between the outer balloon and the inner balloon is provided, said intermediate space connecting
to a channel for connection to said medium storage unit, wherein the intermediate space between the outer balloon and the
inner balloon, the connection channel and the medium storage unit form a closed system wherein no medium is introduced into
the closed system from outside the closed system and no medium is withdrawn from the closed system, wherein a defined media
volume, by means of which the position of the balloon catheter can be examined precisely, is provided in the closed system,
wherein said defined media volume is provided in the intermediate space, at least temporarily, and wherein a fluid of said
defined media volume is displaced to the medium storage unit by filling of the inner balloon to a standard state such that
a distance between the outer balloon and the inner balloon is maintained in the standard state, said defined media volume
being a liquid or gaseous contrast agent.

US Pat. No. 9,360,683

ANTI MYOPIA LENS

Carl Zeiss Meditec AG, J...

1. A method of providing contact lenses for preventing or treating myopia in a patient, comprising:
providing instructions to a prescribing professional to perform the following:
determine a working distance for near viewing;
determine an accommodative requirement commensurate with the working distance;
determine a convergence requirement commensurate with the working distance;
prescribe a pair of multifocal contact lenses having a compensatory near add power located in a near add portion that, when
used, reduces the accommodation required while viewing at the working distance to be substantially zero;

prescribe the multifocal contact lens to further have a convergence support prescription associated with the near add portion
that reduces the convergence required while viewing at the working distance to be substantially reduced to zero;

providing the contact lenses by receiving an order for prescribed contact lenses;
manufacturing or selecting the prescribed contact lenses to include compensatory near add structures to meet the near add
power prescribed and to have convergence support structures to meet the convergence support prescription prescribed; and

delivering the prescribed contact lenses to the prescribing professional or to the patient.

US Pat. No. 9,320,650

METHOD AND APPARATUS FOR PRECISION WORKING OF AN EYE

Carl Zeiss Meditec AG, J...

1. A method for precise working of eye tissue comprising:
a step of providing laser pulses with a pulse length between 50 fs and 1 ps and with a pulse repetition rate of greater than
125 kHz and with a wavelength between 600 and 2000 nm for acting on the eye tissue to be worked.

US Pat. No. 9,962,076

IMAGING SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A method of inspecting an eye, the method comprising:operating an imaging system in one of a first mode of operation and a second mode of operation;
wherein the imaging system comprises a microscope system and an OCT system;
wherein the microscope system is configured to image an object plane onto an image plane and wherein the OCT system is configured to generate an OCT measuring beam of OCT measuring light;
wherein the object plane of the objective lens is located in a region of an anterior portion of the eye in the first mode of operation, and the object plane or an image of the object plane is located in a region of a retina of the eye in the second mode of operation;
wherein an axial field of view of the OCT system in the first mode of operation is greater than the axial field of view of the OCT system in the second mode of operation.

US Pat. No. 9,943,441

APPARATUS AND METHOD FOR GENERATING CUT SURFACES IN THE CORNEA OF AN EYE FOR CORRECTION OF AMETROPIA

Carl Zeiss Meditec AG, J...

1. A method for generating cut surfaces in a cornea of an eye to correct ametropia using an apparatus, said method comprising:providing the apparatus including a laser unit, which focuses pulsed laser radiation into the cornea at a focal point and moves said focal point within the cornea to generate cut surfaces within the cornea, and a control unit, which controls the laser unit for generating cut surfaces;
forming at least one cut surface as an opening cut by application of the pulsed laser radiation from the laser unit, the opening cut extending from an anterior corneal surface into the cornea;
forming at least one further cut surface as a relieving cut by application of the focused pulsed laser radiation from the laser unit, the relieving cut extending from the anterior corneal surface into the cornea and not extending to a cut surface of a lenticle formed in the cornea; and
selecting a position and a shape of the relieving cut such that the relieving cut contributes to the correction of the ametropia of the eye.

US Pat. No. 9,958,392

OPTICAL FILTER SYSTEM AND FLUORESCENCE OBSERVATION SYSTEM

CARL ZEISS MEDITEC AG, J...

1. An optical filter system for fluorescence observation, wherein the filter system comprises an illumination light filter and an observation light filter;wherein the observation light filter has the following transmission characteristics in a wavelength range from 380 nm to 725 nm:
at least two non-overlapping transmitting regions of the observation light filter, wherein each of the at least two transmitting regions of the observation light filter ranges from a first wavelength to a second wavelength being greater than the respective first wavelength, respectively, and has a mean transmittance greater than a first value within its range, respectively; and
plural blocking regions of the observation light filter,
wherein the plural blocking regions of the observation light filter include a first blocking region of the observation light filter, wherein the first blocking region of the observation light filter ranges from 380 nm to a smallest one of the first wavelengths of the at least two transmitting regions of the observation light filter and has a mean transmittance smaller than a second value within its range; and
wherein the plural blocking regions of the observation light filter include at least one second blocking region of the observation light filter, wherein each of the at least one second blocking regions of the observation light filter adjoins two different transmitting regions of the at least two non-overlapping transmitting regions of the observation light filter, respectively, and has a mean transmittance smaller than a third value within its range, respectively;
wherein the illumination light filter has the following transmission characteristics in the wavelength range from 380 nm to 725 nm:
plural transmitting regions of the illumination light filter,
wherein the plural transmitting regions of the illumination light filter include a first transmitting region of the illumination light filter, wherein the first transmitting region of the illumination light filter ranges from 380 nm to a wavelength smaller than the smallest one of the first wavelengths of the at least two transmitting regions of the observation light filter and has a mean transmittance greater than a fourth value within its range; and
wherein the plural transmitting regions of the illumination light filter further include at least one second transmitting region of the illumination light filter, wherein each of the at least one second transmitting regions of the illumination light filter is a wavelength range within one of the at least one second blocking regions of the observation light filter, respectively, and has a mean transmittance greater than a fifth value within its range, respectively; and
plural blocking regions of the illumination light filter,
wherein each of the plural blocking regions of the illumination light filter is a wavelength range comprising one of the plural transmitting regions of the observation light filter and has a mean transmittance smaller than a sixth value within its range, respectively;
wherein the first transmitting region of the illumination light filter contains a third transmitting region in a wavelength range between 440 nm and 560 nm having a width greater than 45 nm, wherein the third transmitting region has a mean transmittance less than 0.8; and
wherein the mean transmittance of the first transmitting region is greater than the mean transmittance of the third transmitting region.

US Pat. No. 9,895,058

HEADS-UP VISION ANALYZER

CARL ZEISS MEDITEC AG, J...

1. A method for determining a prescription of visual aids for first and second eyes of an individual, the method comprising:
providing first and second targets respectively corresponding to the first and second eyes of the individual;
illuminating the first and second targets using at least one illumination device;
disposing a first beam splitter in front of the first eye so as to reflect visible light from the first target into the first
eye and to transmit visible light from space behind the beam splitter into the first eye so that a virtual image of the first
target appears to the individual as a heads-up display floating in the space behind the beam splitter in a line of sight of
the first eye;

disposing a second beam splitter in front of the second eye so as to reflect visible light from the second target into the
second eye and to transmit visible light from space behind the beam splitter into the first eye so that a virtual image of
the second target appears to the individual as a heads-up display floating in the space behind the beam splitter in a line
of sight of the second eye;

selecting a spherical correction for each of the first and second eyes using respective first and second spherical correction
devices;

selecting a cylindrical correction for each of the first and second eyes using respective first and second cylindrical correction
devices; and

determining the prescription of visual aids for the first and second eyes based respectively on the selected spherical correction
and cylindrical correction for the first and second eyes.

US Pat. No. 9,649,027

DEVICE FOR RELIABLY DETERMINING BIOMETRIC MEASUREMENT VARIABLES OF THE WHOLE EYE

Carl Zeiss Meditec AG, J...

1. A device for measuring biometric variables of eyes for calculating intraocular lenses, comprising:
a multi-point keratometer; and
an OCT arrangement:
wherein the multi-point keratometer comprises keratometer measurement points and wherein the keratometer measurement points
are illuminated telecentrically and detected telecentrically;

wherein the OCT arrangement comprises a laterally scanning swept-source system with a detection region detecting a whole eye
over a whole axial length of the eye; and

wherein a scanning direction of the OCT arrangement is aligned such that at least one B-scan of the OCT runs through at least
one of the keratometer measurement points.

US Pat. No. 10,113,864

METHOD FOR DETERMINING THE REGISTRATION OF A STRUCTURE ON A PHOTOMASK AND APPARATUS TO PERFORM THE METHOD

Carl Zeiss SMT GmbH, Obe...

1. A computer-implemented method comprising:simulating, using a processor, a second aerial image from pattern specifications of a mask, including determining said second aerial image as a matrix composed of pixels having intensity values, taking as a basis the pattern specifications of the mask in the form of a transmission function that has, at least in part, a higher resolution than a first aerial image of the mask that was captured by a position measuring device, the first aerial image having a feature, the second aerial images also having the feature; and
determining, using the processor, a registration error of the feature on the mask based on a comparison of the simulated second aerial image and the first aerial image, the registration error indicating a deviation of a nominal position of the feature from its actual position on the mask.

US Pat. No. 9,541,748

SURGICAL MICROSCOPE OBJECTIVE HAVING AN ADJUSTABLE FOCAL INTERCEPT

Carl Zeiss Meditec AG, J...

1. A surgical microscope objective through which an object can be viewed, the surgical microscope objective defining an optical
axis and having an adjustable focal intercept, the surgical microscope objective comprising:
an objective body;
a negative member fixedly mounted in said objective body so as to be immovable with respect thereto;
said negative member facing toward the object and having a lateral edge;
a positive member mounted in said objective body so as to be displaceable therein;
a frame for accommodating said positive member therein;
a first guide section configured on said objective body;
said frame having a first guide part guided on said first guide section to movably guide said frame with said positive member
in the direction of said optical axis;

a second guide section configured on said objective body;
said frame having a second guide part disposed in spaced relationship to said first guide part and said second guide part
being guided on said second guide section and said second guide part being movable between said lateral edge of said negative
member and said objective body;

said second guide part being arranged offset concentrically to said first guide part in the direction of said optical axis
toward said negative member; and,

said first guide part and said first guide section conjointly defining a first contact interface and said second guide part
and said second guide section conjointly defining a second contact interface in spaced relationship to said first interface
so as to counteract tilting of said positive member accommodated in said frame as said frame is moved along said optical axis
relative to said objective body.

US Pat. No. 10,028,861

CONTROL ARRANGEMENT FOR AN OPHTHALMIC SURGICAL SYSTEM

Carl Zeiss Meditec AG, J...

1. A control arrangement for an ophthalmic surgical system for phacoemulsifying an eye lens, the system including:an aspiration line for drawing off fluid and shattered lens particles of the eye lens;
a phaco handpiece having a needle;
said aspiration line running within said needle and being configured to impart ultrasonic energy to said phaco handpiece for shattering said eye lens via a longitudinal vibration of said needle; and,
said control arrangement comprising:
a transmitter configured to irradiate electromagnetic radiation;
a coupling unit having a distal end and being configured to conduct at least one part of said irradiated electromagnetic radiation to said distal end;
said distal end being disposed outside of said aspiration line so as to cause said at least one part of said electromagnetic radiation to be coupled into said aspiration line;
a receiver configured to receive at least a part of said electromagnetic radiation;
a control unit configured to control an absolute value of a parameter of said ophthalmic surgical system in dependence upon the amount of the received electromagnetic radiation; and,
said electromagnetic radiation being a pulsed infrared radiation having an irradiance of a maximum of 0.1 W/cm2 and said electromagnetic radiation having a wavelength greater than 750 nanometers.

US Pat. No. 9,615,740

EYE SURGERY MICROSCOPE HAVING AN ENTITY FOR MEASURING AN AMETROPIA

CARL ZEISS MEDITEC AG, J...

1. A microscope for usage in eye surgery, wherein the microscope provides an imaging beam path for imaging a portion of an
eye of a patient and a measurement beam path for measuring an ametropia of the eye of the patient, and wherein the microscope
comprises:
an objective lens traversed by the imaging beam path and having an object plane in which the eye of the patient is disposable;
at least one of at least one ocular disposed in the imaging beam path behind the objective lens for generating an image of
the object plane and a camera disposed in the imaging beam path behind the objective lens for detecting an image of the object
plane,

a measurement light source for generating a measurement light beam;
a measurement module disposed in the measurement beam path and having at least one light detector detecting measurement light;
optics traversed by the measurement beam path for directing the measurement light beam onto a retina of the eye of the patient
and for providing measurement light reflected at the retina to the measurement module; and

a controller;
wherein the measurement module and the controller are configured to determine a position of an image of the retina along the
measurement beam path, wherein the image of the retina is generated by the optics, and to output a measurement value representing
the ametropia of the eye of the patient.

US Pat. No. 9,733,463

SURGERY SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A surgery system comprising:
a camera and optics, wherein the optics are configured to image a field of view onto the camera, wherein the camera is configured
to obtain two-dimensional camera images of the field of view and to generate camera image data representing the camera images;

an OCT system configured to perform depth scans at selectable locations contained in the field of view and to generate depth
scans data representing the depth scans;

a data memory storing geometry data of at least one surgical tool;
a controller configured to:
identify a first portion of the at least one surgical tool in the camera images by object recognition using the geometry data
of the at least one surgical tool;

determine first locations and second locations in the field of view, wherein the at least one surgical tool is located at
the first locations and wherein the second locations are located aside of the at least one surgical tool;

trigger the OCT system to perform first depth scans at the determined first and second locations;
identify a second portion of the at least one surgical tool in the first depth scans by object recognition using the geometry
data of the at least one surgical tool;

generate a first image representing at least one third portion of the at least one surgical tool, wherein a shape of a representation
of the at least one third portion of the at least one surgical tool is extracted from the geometry data and wherein a position
of the representation of the at least one third portion of the at least one surgical tool in the generated first image is
based on the identified second portion of the at least one surgical tool.

US Pat. No. 9,554,943

OPHTHALMOLOGICAL DEVICE

Carl Zeiss Meditec AG, J...

1. An ophthalmic instrument for the application of laser radiation in an eye, for the examination and/or surgical laser treatment
of the cornea and the lens of the eye, comprising:
a femtosecond laser as a radiation source for laser radiation,
a contact glass with a concave contact surface that is applied onto the cornea to suppress eye movement,
an optical entrance system having a refractive power ratio that is variable;
an objective from which a beam emerges that is focused in the direction of the eye,
optical assemblies which are arranged in front of the objective as seen in the beam direction, and which in operative connection
with the objective selectively vary the focus position in the coordinate direction X,Y and Z either within the region of the
cornea or within the region of the lens of the eye,

the objective being movable relative to the eye or having at least one lens group the position of which relative to the eye
is variable,

the variation of the position of the lens group or of the entire objective shifting the focus position from the region of
the cornea to the region of the lens of the eye and vice versa;

the optical entrance system including at least one optical element that is shiftable between a first position and a second
position such that shifting of the at least one optical element varies an aperture angle ? on a side proximate the eye by
variation of the refractive power ratio of the optical entrance system and, thereby, a diameter of the beam emerging from
the optical entrance system is also variable, the aperture angle ? being smaller when the focus position is in the region
of the lens of the eye than when the focus position is in the region of the cornea.

US Pat. No. 9,795,452

TREATMENT APPARATUS FOR A SUBRETINAL INJECTION AND METHOD FOR ASSISTING IN A SUBRETINAL INJECTION

Carl Zeiss Meditec AG, J...

1. A treatment apparatus for a subretinal injection into an eye, the treatment apparatus comprising:
a three-dimensional imaging device configured to generate a three-dimensional image of a retina and a choroid of the eye;
a planning device configured for inputting at least one set position (S1, S2) for an injection instrument that is to be used for injection;

said at least one set position (S1, S2) being a location indication in said three-dimensional image;

a two-dimensional imaging device configured to generate a surface image of the retina;
said two-dimensional imaging device being further configured to ascertain in said surface image at least one location which
in said surface image corresponds to said at least one set position (S1, S2) indicated in said three-dimensional image;

said two-dimensional imaging device being further configured to insert into said surface image at least one mark corresponding
to said at least one location ascertained so as to form a supplemented surface image; and,

a display device configured to display said supplemented surface image.

US Pat. No. 9,662,010

OPTICAL SYSTEM, COMPRISING A MICROSCOPY SYSTEM AND AN OCT SYSTEM

CARL ZEISS MEDITEC AG, J...

1. An optical system for inspecting an eye comprising:
a microscopy system for generating an image of an object region in an image plane;
wherein the microscopy system comprises a zoom system for varying an imaging magnification of the generation of the image
through a variation of a zoom magnification of the zoom system;

an OCT system, which is configured to generate a measurement beam, which is incident on the object region in a converging
manner to form a measurement focus which comprises a beam waist;

wherein the optical system comprises a controller for controlling a beam waist diameter of the beam waist and for controlling
the zoom magnification;

wherein the controller is configured for a coupled control of the beam waist diameter and the zoom magnification according
to a predefined dependency between the beam waist diameter and the zoom magnification; and

wherein the controller is configured for selectively activating and deactivating the coupled control of the beam waist diameter
and the zoom magnification.

US Pat. No. 10,139,614

MICROSCOPE SYSTEM AND MICROSCOPY METHOD USING DIGITAL MARKERS

CARL ZEISS MEDITEC AG, J...

1. A microscope system comprising:a microscope for generating a microscopic image of an area of observation to be studied;
a camera for recording image-based information on the area of observation to be studied and for generating a digital image of the area of observation to be studied;
a storage and evaluation unit connected to the microscope and the camera for detecting parameter settings of the microscope associated with image information,
a display for rendering visible the digital image of the area of observation to be studied, and
an input device connected to the storage and evaluation unit and to the display, the input device configured to embed digital markers for marking observed objects in the digital image when the digital image is displayed on the display,
wherein the storage and evaluation unit is designed to select and store information on each digital marker to associate the digital marker with a position of the observed object in the area of observation and in the digital image of the area of observation at a later point in time, the digital marker is embedded at a location in the digital image characterized by the image information, and
wherein the storage and evaluation unit is configured to evaluate the area of observation periodically by image processing algorithms and synchronize the position of the digital markers to the position of the observed object in an event of changes in the observed object in the area of observation or in an event of movement of the microscope,
wherein the storage and evaluation unit is configured to analyze the image information contained in the digital image in the vicinity of a respective marker describe the image information with respect to characteristic features, associate the characteristic features with the respective marker and store the association such that it is retrievable;
wherein the storage and evaluation unit is designed to detect the parameter settings of zoom and focus of the microscope, and
the storage and evaluation unit is embodied such that the position of the marker in the area of observation can be associated again at a later point in time with the position of the originally marked observed object in the area of observation and the position of the marker and hence of the marked observed object in the area of observation can be followed over time, and
the storage and evaluation unit is designed to analyze image information in the vicinity of the respective digital marker with the aid of feature descriptors and describe it on the basis of characteristic features.

US Pat. No. 9,919,081

LIQUIDS AND GELS FOR THE OPHTHALMOLOGY AND MICROSCOPY SYSTEM FOR OBSERVING THE SAME

CARL ZEISS MEDITEC AG, J...

1. An ophthalmology microscopy-system for application in a cataract-surgery, wherein the ophthalmology microscopy-system is
an optical reflected light microscope and includes:
an imaging system providing two imaging beam paths imaging an object disposable in a focal plane of the imaging system in
a magnifying way to a multidimensional image of the object, wherein the imaging beam paths intersect in the focal plane enclosing
an angle between 0.5° and 10° ;

at least one photo detector configured to detect an intensity of radiation guided in at least one of the two imaging beam
paths of the imaging system and to output an electric signal depending on the detected intensity of the radiation;

a suction apparatus having a suction pump connectable to a suction head, wherein the suction head is introducible into an
eye of a patient; and

a controller configured to control a suction rate of the suction pump of the suction apparatus depending on the electric signal
output by the at least one photo detector,

wherein the at least one photo detector is configured to detect an intensity of a radiation emitted by a substitute material
disposed in the eye of the patient and to output the electric signal depending on the detected intensity of the radiation
emitted by the substitute material disposed in the eye of the patient.

US Pat. No. 9,543,107

METHOD AND APPARATUS FOR GENERATING X-RAY RADIATION

CARL ZEISS MEDITEC AG, J...

1. Method for generating a specific radiation dose rate curve for an X-ray radiation for irradiation of a substrate, wherein
the specific radiation dose rate curve represents a radiation dose rate as a function of distance, characterized in that the
specific radiation dose rate curve is generated by selecting at least two predetermined radiation dose rate curves which are
different from the specific radiation dose rate curve which is to be generated, and each of which represents a radiation dose
rate as a function of distance, and by composing the specific radiation dose rate curve proportionally from the at least two
predetermined radiation dose rate curves.

US Pat. No. 9,918,874

OPHTHALMOLOGICAL LASER SYSTEM

Carl Zeiss Meditec AG, J...

1. A method for photodisruptive laser treatment by application of laser energy to ocular tissue, the ocular tissue including
a crystalline lens or a cornea, the method comprising:
determining irradiation control data for photodisruptions at a plurality of irradiation points in the interior of the ocular
tissue to create at least one predetermined target incision, wherein the irradiation points are arranged regularly and in
such a way that a compensation of a refractive deficit results through constructive interference in the light passing through
the ocular tissue; and

controlling a laser to irradiate the ocular tissue according to the determined irradiation control data.

US Pat. No. 9,727,962

SYSTEM FOR VISUALIZING TISSUE IN A SURGICAL REGION

Carl Zeiss Meditec AG, J...

1. A system for visualizing characteristic tissue in a surgical region to determine an edge region of tumor tissue in a human
brain, the system comprising:
a detection unit including at least one sensor and configured to detect light from an object point (x, y) in said surgical
region;

a computer unit connected to said detection unit and having a computer processor;
a visualization unit having a display and being driven by said computer unit and configured to display unevaluated information
defined by an image of an area within said surgical region;

said computer unit including a non-transitory computer readable storage medium having program code stored therein;
said computer processor being configured to run said program code;
said computer unit being configured to determine a color coordinate having a position in a color region as to said light from
said object point (x, y);

said computer unit being further configured to compute, in dependence upon said position of the determined color coordinate
in said color region, a two state digital color coordinate information (“0”, “1”) for controlling said visualization unit
by comparing information as to said determined color coordinate to a characteristic reference color coordinate (xc, yc) typical for said edge region of said tumor tissue in said color region in accordance with said program code wherein said
two state digital color coordinate information (“0”, “1”) can have a first state (“0”) or a second state (“1”) and wherein
said color coordinate information (“0”, “1”) is obtained by determining whether a distance norm ?E=?(x, y);(xc,yc)? between the color of said object point (x, y) and the color of said reference color coordinate (xc, yc) exceeds a threshold As with the first state (“0”) of said two state digital color coordinate information (“0”, “1”) being then associated with said
object point (x, y); whereas, if said distance norm ?E is less than said threshold As, then the second state (“1”) of said two state digital color coordinate information (“0”, “1”) is assigned to a pixel; and,

said visualization unit being further configured to display evaluated information defined by said two state digital color
coordinate information (“0”, “1”) in said image of said area within said surgical region so as to distinguish the edge region
of tumor tissue in the human brain from remaining tissue.

US Pat. No. 9,538,914

MICROSCOPY SYSTEM FOR OBSERVING FLUORESCENCE IN OPHTHALMOLOGY

CARL ZEISS MEDITEC AG, J...

1. An ophthalmology microscopy system for observing fluorescence, comprising:
an imaging system providing at least one optical imaging path producing a magnified multi-dimensional image of an object disposable
in a focal plane of the imaging system, with the imaging system comprising at least on optical observation filter; and

a first illumination system providing a first illumination beam path intersecting the focal plane of the imaging system at
a variable angle of less than 90°, or less than 80°, or less than 75°;

wherein the microscopy system comprises first and second operating states;
wherein radiation passing through the first illumination beam path in the first operating state has at least in a section
along the illumination beam path a spectrum being free of a pass band of the observation filter; and

wherein radiation passing through the first illumination beam path in the second operating state has a spectrum with a bandwidth
of at least 200 nm, or at least 250 nm, and being in a range from 380 nm to 780 nm,

wherein the first illumination system comprises a handle piece comprising a rigid light guide,
wherein the rigid light guide is configured for being disposed in at least one of a visceral cavity, hollow organ and vitreous
body of an eye ball.

US Pat. No. 9,814,382

METHOD FOR DETERMINING THE POWER OF AN INTRAOCULAR LENS

Carl Zeiss Meditec AG, J...

1. A method for calculating a power of an intraocular lens comprising the steps of:
measuring an axial separation (ACD') between a front surface of a cornea and a plane of an iris root; and
determining the power of the intraocular lens using the measured axial separation together with other measured parameters
and empirically determined lens constants.

US Pat. No. 9,572,716

APPARATUS AND METHOD FOR GENERATING CUT SURFACES IN THE CORNEA OF AN EYE FOR CORRECTION OF AMETROPIA

Carl Zeiss Meditec AG, J...

1. A method for generating cut surfaces in a cornea of an eye in order to correct ametropia using an apparatus, said method
comprising:
providing the apparatus including a laser unit, which focuses pulsed laser radiation into the cornea and moves said focused
pulsed radiation therein in order to generate cut surfaces within the cornea, and a control unit, which controls the laser
unit for generating cut surfaces;

forming at least one cut surface as an opening cut by application of the pulsed laser radiation from the laser unit, the opening
cut extending from an anterior corneal surface into the cornea;

forming a further cut surface having several relieving cuts by application of the focused pulsed laser radiation from the
laser, the several relieving cuts extending from the anterior corneal surface into the cornea; and selecting a position and
a shape of the several relieving cuts such that the several relieving cuts contribute to the correction of the ametropia of
the eye.

US Pat. No. 10,130,248

METHOD FOR REALIZING OCULAR FUNDUS PHOTOGRAPHS THAT ARE CORRECTED FOR SCATTERED LIGHT

Carl Zeiss Meditec AG, J...

1. A method for realizing ocular fundus images that are corrected for scattered light using a digital fundus camera, the method comprising:a) illuminating the ocular fundus by application of an illumination source located within the digital fundus camera and directed through optics of the digital fundus camera into an eve and onto the ocular fundus, and
b) capturing a digital image of the ocular fundus through the optics of the digital fundus camera in which an imaged surface area of the ocular fundus is larger than an illuminated surface area of the ocular fundus,
wherein in the digital image of the ocular fundus realized in b) a scattered light intensity is determined and is used for a correction, the method further comprising
c) defining, by application of the digital fundus camera, measurement points or a measurement area, the measurement points or the measurement area for determining the scattered light intensity being located in a non-illuminated area of the ocular fundus adjacent to or surrounding the illuminated area of the ocular fundus;
d) in the case of measurement points in the non-illuminated area of the ocular fundus, eliminating outliers and after the outliers have been eliminated, averaging values of scattered light intensity determined at said measurement points to determine an averaged scattered light intensity by application of the digital fundus camera; and
e) using the average scattered light intensity thus determined to correct said image of the ocular fundus realized in method step b) or to define the severity of a cataract by application of the digital fundus camera.

US Pat. No. 9,766,443

VARIOSCOPE OPTICAL UNIT AND MICROSCOPE HAVING A VARIOSCOPE OPTICAL UNIT

CARL ZEISS MEDITEC AG, J...

1. A microscope comprising: a varioscope optical unit having a positive member that is formed from a lens or lens group and
has a positive refractive power, and a negative member that is formed from a lens or lens group and has a negative refractive
power, the positive member and the negative member being arranged along an optical axis, the microscope further comprising
an illumination optical unit with a light source that directs light along an illumination beam path through the varioscope
optical unit at an angle to the optical axis of the varioscope optical unit and to an observation object, wherein
the illumination beam path is asymmetrically coupled into the varioscope optical unit such that the illumination beam path
runs asymmetrically through the positive member and the negative member where the positive member is displaceable relative
to the negative member other along the optical axis;

the positive member and the negative member are arranged along the optical axis such that the negative member is arranged
in a fixed manner between the positive member and the observation object when viewed in an observation direction,

at least one of the positive member and the negative member is displaceable along the optical axis, wherein a depth of field
can be varied by displacing the positive member or the negative member,

the positive member has a first termination lens surface that terminates the positive member counter to the observation direction,
and a second termination lens surface that terminates the positive member in the observation direction,

the negative member has a first termination lens surface that terminates the negative member counter to the observation direction,
and a second termination lens surface that terminates the negative member in the observation direction,

the second termination lens surface of the positive member and the first termination lens surface of the negative member are
concave when viewed in the observation direction, and the second termination lens surface of the negative member is convex
when viewed in the observation direction, the second termination lens surface of the positive member and the first termination
lens surface of the negative member each have a radius of curvature with an absolute value of at most 500 mm, and the second
termination lens surface of the negative member has a radius of curvature with an absolute value of at most 70 mm, and

the first termination lens surface of the negative member is formed in a first lens element, the first lens element being
composed of a material with a refractive index of at most 1.6.

US Pat. No. 10,048,484

IMAGING SYSTEM AND IMAGING METHOD

Carl Zeiss AG, Oberkoche...

1. An imaging system, comprising:an imaging lens system for generating an image of an object in an image plane, including
an optical component having an alterable refractive power and a rotation-symmetrical optical effect; and
an illumination unit which illuminates the object with a pulsed illumination effect,
wherein the optical component comprises two refractive elements, each having at least one free-form surface, and
wherein the two refractive elements are displaceable relative to each other such that an entirety of the first of the two refractive elements is shifted with respect to the second of the two refractive elements, the displacement being in a direction transverse to an optical axis of the imaging lens system to alter the refractive power.

US Pat. No. 9,962,292

AFTER-TREATMENT OF REFRACTION CORRECTION BY OPHTHALMIC SURGERY

Carl Zeiss Meditec AG, J...

1. A planning device for generating control data for a treatment apparatus for ophthalmic surgery, which cuts at least one incision surface in a cornea, using a laser device, the planning device including:a calculation device comprising a computer configured to receive data of a previously-introduced cornea incision surface having an existing flap incision and an existing opening incision extending from an exterior surface of the cornea to the existing flap incision so as to form at least a partial existing corneal flap, and to establish a new cornea incision surface, based on the data of the previously-introduced cornea incision surface and to generate a control data set for controlling the laser device for the new cornea incision surface,
wherein the computer of the calculation device is further configured to determine the new cornea incision surface having a new flap incision that is ring-shaped and located posterior to the existing flap incision, a new opening incision located lateral to the existing flap incision and extending from the exterior surface of the cornea to the new flap incision, and a connecting mantle incision connecting the new flap incision to the existing flap incision in such a manner that the existing flap incision of the previously-introduced cornea incision surface is intersected by at least a part of the connecting mantle incision of the new cornea incision surface at an angle between 60° and 120°, such that a new hinged corneal flap is formed, the new hinged corneal flap including portions of the at least partial existing corneal flap.

US Pat. No. 9,820,820

MODULE FOR A VISUALIZATION APPARATUS FOR VIEWING AN OBJECT

Carl Zeiss Meditec AG, J...

1. A module for a visualization apparatus for viewing an object, the visualization apparatus having a base body and an imaging
optic defining an optical viewing beam path and being accommodated in said base body; said imaging optic being configured
for generating a viewing image of a region of the object with said optical viewing beam path; the module comprising:
a display unit having a display and being configured for visualizing an image superposed on said viewing image of said object
region;

said superposed image having orientation information in said optical viewing beam path;
an optical channel for said optical viewing beam path;
an image acquisition unit having an image sensor for detecting an image of the region of the object;
an in-coupling beam splitter arranged in said optical channel;
said display and said image sensor conjointly defining an optical beam path running from said display to said image sensor
and passing through said beam splitter;

a switching unit for selectively passing and blocking said optical beam path;
said in-coupling beam splitter being configured to deflect said optical beam path from said display into said optical channel
so as to be superposed on said optical viewing beam path;

said switching unit having a first switching state wherein an image of a geometric structure shown on said display is made
available on said image sensor via said optical beam path and having a second switching state, which is different from said
first switching state, wherein said optical beam path is blocked to prevent said geometric structure shown on said display
from reaching said image sensor;

an out-coupling beam splitter arranged in said optical channel for said optical viewing beam path;
said out-coupling beam splitter being configured to conduct said viewing image of said object region to said image acquisition
unit;

said switching unit including a beam deflection system configured to deflect said optical beam path coming from said display
and passing through said in-coupling beam splitter and then being conducted to said image sensor via said out-coupling beam
splitter;

said in-coupling beam splitter having a side facing away from said display and said out-coupling beam splitter having a side
facing away from said image acquisition unit;

said beam deflection system including a first mirror surface and a second mirror surface; and,
said beam deflection system being configured to guide said optical beam path coming from said display at said side of said
in-coupling beam splitter via reflection onto said first mirror surface and then to said second mirror surface which, in turn,
reflects said optical beam path to said side of said out-coupling beam splitter.

US Pat. No. 9,649,024

METHOD FOR THE MODEL-BASED DETERMINATION OF THE BIOMETRY OF EYES

Carl Zeiss Meditec AG, J...

1. A method of model-based determination of the biometry of eyes, based on optical coherence tomography (OCT), comprising
illuminating the eye by a light source via a scanning unit, wherein a focus of a measuring light beam in the eye is movable
or switchable laterally and/or axially by application of an adjusting device;

detecting light components back-scattered from boundary surfaces and from tissue of the eye by a sensor via an interferometer;
relaying information from the sensor to a control and evaluation unit;
performing one or more scans having same or different scan patterns, same or different focus settings or a combination of
the foregoing by application of the scanning unit, and receiving the scans by the sensor via the interferometer and relaying
the one or more scans to the control and evaluation unit, which adapts a parametric eye model to create an adapted parametric
eye model, which includes at least two boundary surfaces present in the eye;

deriving biometric measured values from the adapted parametric eye model; and
representing individual scans, all scans, the adapted parametric eye model or a combination thereof via a user interface.

US Pat. No. 10,302,932

MICROSCOPE SYSTEM AND MICROSCOPY METHOD USING DIGITAL MARKERS

CARL ZEISS MEDITEC AG, J...

1. A microscope system comprising:a microscope for generating a microscopic image of an area of observation to be studied;
a camera for recording image-based information on the area of observation to be studied and for generating a digital image of the area of observation to be studied;
a storage and evaluation unit connected to the microscope and the camera for detecting parameter settings of the microscope associated with image information,
a display for rendering visible the digital image of the area of observation to be studied, and
an input device connected to the storage and evaluation unit and to the display, the input device configured to embed digital markers for marking observed objects in the digital image when the digital image is displayed on the display,
wherein the storage and evaluation unit is designed to select and store information on each digital marker to associate the digital marker with a position of the observed object in the area of observation and in the digital image of the area of observation at a later point in time, the digital marker is embedded at a location in the digital image characterized by the image information, and
wherein the storage and evaluation unit is configured to evaluate the area of observation periodically by image processing algorithms and synchronize the position of the digital markers to the position of the observed object in an event of changes in the observed object in the area of observation or in an event of movement of the microscope,
wherein the storage and evaluation unit is configured to analyze the image information contained in the digital image in the vicinity of a respective marker describe the image information with respect to characteristic features, associate the characteristic features with the respective marker and store the association such that it is retrievable;
wherein the storage and evaluation unit is configured to perform at least one of the following:
detect at least one of: parameter settings of zoom and a focus of the microscope;
associate, again at a later point in time, the position of the digital marker in the area of observation with at least one of the position of the originally marked observed object in the area of observation and the position of the marker and hence of the marked observed object in the area of observation can be followed over time; and
analyze image information in the vicinity of the respective digital marker with the aid of feature descriptors and describe it on the basis of characteristic features.

US Pat. No. 9,579,019

EYE SURGERY SYSTEM AND METHOD OF OPERATING AN EYE SURGERY SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A method of operating an eye surgery system, wherein the eye surgery system comprises:
a microscope;
a stand carrying the microscope and comprising plural components which are displaceable relative to each other, and plural
actuators for positioning the components relative to each other; and

an apparatus for measuring a refraction of an eye which is commonly carried with the microscope on the stand; and
wherein the method comprises:
operating the actuators such that the apparatus for measuring the refraction of the eye is located in a measurement position
relative to the eye;

measuring at least one condition of the eye and determining at least one condition value representing the at least one measured
condition of the eye;

measuring the refraction of the eye using the apparatus for measuring the refraction of an eye and determining at least one
refraction value presenting the measured refraction of the eye, wherein a time distance between the measuring of the at least
one condition of the eye and the measuring of the refraction of the eye is smaller than a predetermined duration; and

outputting the at least one refraction value representing the measured refraction of the eye only when the at least one condition
value representing the at least one measured condition of the eye is within a predetermined range of values.

US Pat. No. 9,560,958

METHOD AND APPARATUS FOR SELECTING AN INTRAOCULAR LENS (IOL) AND/OR SURGICAL PARAMETERS WITHIN THE FRAMEWORK OF IOL IMPLANTATIONS

Carl Zeiss Meditec AG, J...

1. A computer implemented method to select an intraocular lens (IOL) and/or surgical parameters in a context of IOL implantation
procedure for a subject, comprising:
receiving input at a central control and evaluation unit via an interface from one or more data source ophthalmological measuring
devices that are operably coupled to the central control and evaluation unit;

varying at least two input parameters selected from a list consisting of: a measured biometric data parameter, an IOL-specific
parameter, a surgical procedure parameter, a post-surgical result parameter, and a diagnostic device parameter from the one
or more data source ophthalmological measuring devices by application of the central control and evaluation unit; and

providing a decision aid output signal from the central control and evaluation unit related to an IOL for a given patient
based on a corresponding output parameter, by rendering to an operator a distribution function based on at least one of said
at least two input parameters,

wherein the corresponding output parameter is determined from at least one of the at least two input parameters, said input
parameters being configured as one of: a predetermined value input parameter, an estimated value input parameter, and a measured
value input parameter, or a mean value thereof.

US Pat. No. 9,610,154

INJECTOR TIP FOR AN OCULAR LENS INJECTOR DEVICE, DEVICE WITH AN INJECTOR TIP AND AN OCULAR LENS, AS WELL AS OCULAR LENS INJECTOR DEVICE

Carl Zeiss Meditec AG, J...

1. An injector tip for an ocular lens injector device,
the injector tip comprising a tapered injection duct having a front end and a rear end and being bounded by an inner wall,
wherein at the inner wall an inwardly extending step is formed, and the step is formed only along part of an entire length
between the front and the rear end of the injection duct and ends at a distance from the front end of the injection duct,
wherein the step in a circulation direction about a central longitudinal axis of the injection duct has a steep step flank
and a flat step flank, which converge at a crown line; and wherein the crown line has a gradually rising first crown line
section and a gradually falling second crown line section; and wherein the crown line has a crown line section formed between
the first and the second crown line sections and extending a constant distance from the central longitudinal axis.

US Pat. No. 9,888,840

METHOD FOR THE OPTIMIZED PREDICTION OF THE POSTOPERATIVE ANATOMICAL POSITION OF AN INTRAOCULAR LENS IMPLANTED IN A PSEUDOPHAKIC EYE

Carl Zeiss Meditec AG, J...

1. A method for optimized prediction of postoperative lens position (LP post) of an intraocular lens to be implanted in a
pseudophakic eye, comprising:
using known measurement values, including comeal thickness (HHD), anterior chamber depth (VKT), eye length (AL) as well as
the distance of the capsular bag equator (KSA) or lens haptic (LH) to the anterior surface of the lens (LV) for calculation;
and
including in the calculation an anatomical, postoperative position (LP an-post) of the intraocular lens (L) to be implanted,
a diameter of the capsular bag and a diameter of a capsulorhexis.

US Pat. No. 9,877,870

DEVICE AND METHOD FOR CONTROLLING A LASER SYSTEM

Carl Zeiss Meditec AG, J...

1. A device for controlling a laser system for treating a crystalline lens using laser-induced disruptions, wherein the laser
system comprises a femtosecond laser and a three dimensional scanner that guides a laser beam produced by the femtosecond
laser, comprising:
an optical detection device that determines a characteristic variable that is characteristic for the occurrence of disruptions;
and

an electronic control device;
wherein the optical detection device is operably connected to the control device and the electronic control device determines
a pulse energy, a number of laser pulses applied to one spot position, a laser spot overlap, a laser spot distance or a combination
of the foregoing for the laser system from the characteristic variable and controls the laser accordingly.

US Pat. No. 9,801,549

APPARATUS FOR FINDING A FUNCTIONAL TISSUE AREA IN A TISSUE REGION

Carl Zeiss Meditec AG, J...

1. An apparatus for finding a functional tissue area in a tissue region, the apparatus comprising:
a measurement illuminating device configured to emit a measurement illumination on to the tissue region;
a camera for capturing light reflected from the tissue region;
said camera being configured to have at least one of a green channel and a blue channel wherein there is a change in at least
one optical property of the light reflected by the tissue region during stimulation of the tissue region undertaken at least
intermittently;

said camera being further configured to emit a camera signal exclusively of at least one of said green channel and said blue
channel;

an evaluation unit for detecting the change in the at least one optical property only via said camera signal and supplying
an output signal; and,

a display unit for displaying said output signal of said evaluation unit for the functional tissue area of the tissue region.

US Pat. No. 9,715,097

STEREOMICROSCOPE HAVING A MAIN OBSERVER BEAM PATH AND A CO-OBSERVER BEAM PATH

Carl Zeiss Meditec AG, J...

1. A stereomicroscope comprising:
a stereoscopic main observer beam path having a main observer zoom system;
a stereoscopic co-observer beam path having a co-observer zoom system and being configured to have a first stereoscopic co-observer
partial beam and a second stereoscopic co-observer partial beam pass therealong;

a main objective common to said main observer beam path and said co-observer beam path;
a geometrical beam splitter arranged between the main objective and the main observer zoom system;
said co-observer beam path being coupled out from the main observer beam path via said geometrical beam splitter;
said co-observer zoom system being disposed in said co-observer beam path downstream of said geometrical beam splitter; and,
said co-observer zoom system including a plurality of lenses having dimensions configured so as to cause both said first and
said second stereoscopic co-observer partial beams to pass through each of said lenses.

US Pat. No. 9,913,752

SURGICAL DEVICE AND SURGICAL METHOD

CARL ZEISS MEDITEC AG, J...

1. A surgical instrument system for ophthalmic surgery in an interior of an eye, comprising:
an OCT apparatus including an interferometer;
an optical fiber coupled to the OCT apparatus and extending a probe arm of the interferometer, the optical fiber having a
tip end;

a hand tool comprising:
a hand piece,
a tube extending away from the hand piece and comprising a distal end portion having a longitudinal axis and a tip end, wherein
a distal portion of the optical fiber is received within the tube;

a beam emitter coupled to the tip end of the optical fiber and configured to emit an OCT measuring beam into an emission direction
of the beam emitter; and

an actuator configured to change the emission direction of the OCT measuring beam relative to the tip end of the distal end
portion;

wherein a first tangent to the longitudinal axis at a proximal end of the distal end portion and a second tangent to the longitudinal
axis at the tip end of the distal end portion form a bending angle of the distal end portion of between 60 and 100 degrees;
and

wherein a first distance between an intersection point of the first tangent with the second tangent and the proximal end is
between 4.5 mm and 8 mm; and

wherein a second distance between the intersection point and the tip end of the distal end portion is between 3 mm and 9 mm.

US Pat. No. 9,885,858

SURGICAL MICROSCOPY SYSTEM AND METHOD FOR OPERATING THE SAME

Carl Zeiss Meditec AG, J...

1. A surgical microscopy system comprising:
a surgical microscope defining an observation beam path and having a control unit and focusable imaging optics for observing
an operation field during a surgical procedure;

a stand having a base;
said surgical microscope being arranged on said stand;
said stand further having at least one of linear drives and rotary joints configured to enable said surgical microscope to
be displaceable along three direction axes (x, y, z) and rotatable about three axes of rotation (?, ?, ?) relative to said
base;

each of said at least one of the linear drives and the rotary joints having at least one of position sensors and rotary angle
sensors assigned thereto for each of said three direction axes (x, y, z);

each of said at least one of the linear drives and the rotary joints having at least one of position sensors and rotary angle
sensors assigned thereto for each of said three axes of rotation (?, ?, ?);

a focusing sensor for a focus point assigned to said focusable imaging optics; and,
a storage device configured to store a position and alignment of said surgical microscope relative to said base as well as
to store said focus point of said focusable imaging optics at said position and alignment so as to permit said surgical microscope
to return to the stored position and alignment and the stored focus point after being displaced therefrom during the course
of the surgical procedure.

US Pat. No. 9,603,701

FLEXIBLE ARTIFICIAL LENS ACCOMMODATED BY MEANS OF PRESSURE OR ELECTRICAL CONDICTIVITY

CARL ZEISS MEDITEC AG, J...

1. An artificial lens for an eye, said artificial lens being a lens implant that is inserted into an eye in place of the natural
lens of the eye, said artificial lens being characterized in that it has a lens comprising of two or more media that are flexible
in shape that come into direct contact with one another, in that the at least two media are disposed in a lens body, in that
the media that are flexible in shape contact on at least one interface and are disposed so that they can be displaced relative
to one another, in that the media that are flexible in shape are each formed as a liquid, in that it has means for changing
at least one of the size and shape of the at least one interface between the media, in that the media are applied to at least
one bearing surface, at least in regions, said bearing surface being an intermediate layer inside said lens body, said intermediate
layer having an opening which is made concentric around an optical axis of said artificial lens, said opening corresponding
to the maximum pupil diameter of the eye for which the artificial lens is specified, and in that one of the media that are
flexible in shape is made in the form of a drop, said medium being fixed in the region of said opening.

US Pat. No. 10,105,262

PRODUCING CUT SURFACES IN A TRANSPARENT MATERIAL BY MEANS OF OPTICAL RADIATION

CARL ZEISS MEDITEC AG, J...

1. A method for producing a cut in a transparent material comprising eye tissue, the method comprisingfocussing optical radiation into the transparent material by using optics which define an optical axis and have in the material an image field of an image field size, and
generating the cut by shifting a focus within the material along an oscillating path which is located in the cut,
wherein generating the cut by shifting the focus within the material along the oscillating path comprises moving a position of the focus in a direction transverse to the optical axis, and during such transverse movement, moving the position of the focus along the oscillating path between an upper axial focus position and a lower axial focus position, wherein the oscillating path comprises upward sections in which the position of the focus moves along the oscillating path against a direction of incidence of the optical radiation with the material, and from the lower axial focus position to the upper axial focus position and downward sections in which the position of the focus moves along the oscillating path with the direction of incidence of the optical radiation with the material, and from the upper axial focus position to the lower axial focus position,
wherein each of the upward sections is asymmetrical to a subsequent and adjacent downward section with respect to an axis which is parallel to the optical axis and runs through a turning point connecting the upward section and the subsequent and adjacent downward section, and
wherein each of the downward sections is asymmetrical to a subsequent and adjacent upward section with respect to an axis which is parallel to the optical axis and runs through a turning point connecting the downward section and the subsequent and adjacent upward section.

US Pat. No. 10,054,775

OPTICAL SYSTEM FOR FLUORESCENCE OBSERVATION

CARL ZEISS MEDITEC AG, J...

1. An optical system for fluorescence observation, comprising:optics including an ocular, a camera, a display, a light source, a first illumination light filter, a first observation light filter, and a controller;
wherein the optics provides a first beam path from the light source to an object region for illuminating the object region,
wherein the optics provides a second beam path from the object region to the ocular for imaging the object region via the ocular,
wherein the optics provides a third beam path from the object region to the camera for imaging the object region onto the camera, and
wherein the optics provides a fourth beam path from the display to the ocular for imaging an image, displayed by the display, via the ocular;
wherein the optical system has a first mode of operation, in which the first illumination light filter is arranged in the first beam path and the first observation light filter is arranged in the third beam path;
wherein the first observation light filter has, in a wavelength range from 380 nm to 725 nm, a transmission characteristics as follows:at least two non-overlapping transmitting regions of the first observation light filter, each of the transmitting regions having, between a first wavelength and a second wavelength, a mean transmittance greater than a first value; andplural blocking regions of the first observation light filter, the plural blocking regions including: a first blocking region of the first observation light filter having, between 380 nm and a smallest one of the first wavelengths of the at least two transmitting regions of the first observation light filter, a mean transmittance smaller than a second value, and at least one further blocking region of the first observation light filter, each of the further blocking regions having, between the second wavelength of one of the at least two transmitting regions of the observation light filter and the first wavelength of a further one of the at least two transmitting regions of the first observation light filter, a mean transmittance smaller than a third value;
wherein the first illumination light filter has, in a wavelength range from 380 nm to 725 nm, a transmission characteristics as follows:
plural transmitting regions of the first illumination light filter, the plural transmitting regions including:
a first transmitting region of the first illumination light filter having, between 380 nm and a wavelength smaller than the smallest one of the first wavelengths of the at least two transmitting regions of the first observation light filter, a mean transmittance greater than a fourth value, and
further transmitting regions of the first illumination light filter, each of the further transmitting regions having, between a wavelength greater than the second wavelength of a transmitting region of the first observation light filter and a wavelength smaller than the first wavelength of a further transmitting region of the observation light filter, a mean transmittance greater than a fifth value; and
plural blocking regions of the first illumination light filter, each of the blocking regions of the first illumination light filter having, between the wavelength smaller than the first wavelength of one of the transmitting regions of the first observation light filter and the wavelength greater than the second wavelength of this transmitting region of the first observation light filter, a mean transmittance smaller than a sixth value;
wherein the controller is configured to process a fluorescent light image obtained by the camera in the first mode of operation by identifying a contiguous fluorescent region in the fluorescent light image obtained in the first mode of operation based on at least one decision parameter, generating a representation of a boundary of the contiguous fluorescent region, generating an image including the representation of the boundary of the contiguous fluorescent region, and supplying the generated image to the display.
US Pat. No. 9,855,170

RE-TREATMENT FOR OPHTHALMIC CORRECTION OF REFRACTION

Carl Zeiss Meditec AG, J...

1. A method of laser-based ophthalmic surgery, wherein a treatment apparatus comprising a laser device is used to generate
at least one cut surface in tissue of an eye by deflecting a laser beam in the eye, said method comprising:
generating corneal data by using an OCT;
defining the cut surface on the basis of the corneal data;
generating a control dataset for the cut surface;
transmitting the control dataset to the treatment apparatus; and
generating the cut surface by controlling the laser device using the control dataset,
wherein the laser device used comprises a laser source emitting the laser beam as a pulsed laser beam having a pulse duration
in the range of between 1 fs and 10 ps generating optical breakthroughs within the eye tissue.

US Pat. No. 9,844,464

METHOD AND APPARATUS FOR PRECISION WORKING OF MATERIAL

Carl Zeiss Meditec AG, J...

1. A method for precision machining of an organic tissue, the method comprising:
providing a radiation source that generates a pulsed laser beam having a plurality of laser pulses;
wherein the pulsed laser beam has a pulse length between 50 fs and 1 ps, a pulse frequency greater than 50 kHz, and an energy
of an individual laser pulse between 100 nJ and 10 ?J; and

providing a beam device that directs the pulsed laser beam to the organic tissue such that a plurality of cuts in the organic
tissue are generated by photodisruption,

wherein the plurality of the cuts divide a portion of the organic tissue into fragments capable of being extracted by a suction
device.

US Pat. No. 9,925,041

EYE LENS HAVING A TORIC REFRACTIVE SURFACE PROFILE AND A SURFACE STRUCTURE THAT IS STEPPED IN A RADIAL DIRECTION

Carl Zeiss Meditec AG, J...

1. An eye lens comprising:an optical part defining a main optical axis (A) and a radial direction;
said optical part, viewed in the direction of said main optical axis (A), having a first optical side and a second optical side disposed opposite to said first optical side;
a toric refractive surface profile formed on at least one of said first optical side and said second optical side;
a surface structure in addition to said toric refractive surface profile;
said surface structure being configured as a stepped surface structure stepped in said radial direction and formed on at least one of said first optical side and said second optical side;
said stepped surface structure including a plurality of steps each having a step tip;
said stepped surface structure having a radial contour course of an envelope connecting said step tips of said steps constituting said stepped surface structure formed on one of said first and said second optical sides; and,
said radial contour course corresponding at least in sections to a second contour course of the other one of said first and second optical sides mirrored on a plane of symmetry (E) of the eye lens perpendicular on said main optical axis (A).

US Pat. No. 9,912,917

VISUALIZATION APPARATUS FOR A SURGICAL SITE

Carl Zeiss Meditec AG, J...

1. A visualization apparatus for a surgical site, comprising:
an image recording unit defining a focal plane and being configured to record an image of an object arranged in said focal
plane of said image recording unit;

said image recording unit including a lens having an optical axis that intersects said focal plane at a point P;
an electronic image representation unit having an image representation surface for reproducing the image recorded by said
image recording unit, wherein said point P is reproduced at an image point P? of said image representation surface of said
image representation unit;

a first mirror unit having a first mirror surface arranged relative to said image representation surface in such a manner
that the image reproduced by said image representation surface is reflected by said first mirror surface;

said first mirror surface having a first center point S; and,
said focal plane, said image representation surface and said first mirror surface being arranged relative to one another in
such a manner that a first observation point B results for which the following applies:

?2 D wherein:
?1=?1/d1
?2=?1/d2
d1=distance PB
d2=distance P?S+distance SB.

US Pat. No. 9,795,474

HYDROPHILIC IOL PACKAGING SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A method of maintaining a hydrophilic intraocular lens in a foldable state without immersing the intraocular lens in liquid,
the method comprising the step of storing the foldable intraocular lens within a substantially air tight container containing
free water, the lens being stored within the container at a location wherein the lens is not immersed in liquid.

US Pat. No. 9,622,659

METHOD FOR DETERMINING THE TOTAL REFRACTIVE POWER OF THE CORNEA OF AN EYE

Carl Zeiss Meditec AG, J...

1. A method for determining total refractive power of a cornea of an eye from measured values of a keratometric or topographical
measurement as well as measured values obtained from depth scans or sectional images, comprising:
a) measuring a radius Ra of an anterior cornea side keratometrically with a first modality comprising a keratometer or topographically with a topographer
to acquire a measurement, and from the measurement, determining a refractive power Ka of the anterior cornea side as follows:


b) determining a radius Rp of a posterior cornea side at least partially with a second modality performing depth scans or sectional images, and from
this determination, a refractive power Kp of the posterior cornea side as follows:


c) determining a central thickness d of the cornea from depth scans or sectional images, and afterward, determining a total
refractive power K of the cornea as follows:

in which K defines the total refractive power of the cornea,
Ka defines the refractive power of the anterior cornea side,

Kp defines the refractive power of the posterior cornea side,

Ra defines the radius of the anterior cornea side,

Rp defines the radius of the posterior cornea side,

n0 defines an index of refraction of air,

n1 defines an index of refraction of the cornea,

n2 defines an index of refraction of aqueous fluid, and

d defines the central thickness of the cornea,wherein the radii Ra, Rp and the thickness d are indicated in meters, and the refractive powers K, Ka, and Kp are indicated in diopters.

US Pat. No. 10,092,448

SCANNING DEVICE

Carl Zeiss Meditec AG, J...

1. A surgical laser system including a scanning device for focusing a luminous beam into a selected range of an eye to be treated, the surgical laser system comprising:a femtosecond surgical laser source that produces the luminous beam, the femtosecond surgical laser source being structured to produce photodisruptions within tissues of the eye to be treated upon focal application of the luminous beam to the tissues;
entrance optics following the femtosecond surgical laser source into which the luminous beam first enters comprising at least a first optical element;
focusing optics by which the luminous beam emitted from the entrance optics is focused on or into the eye to be treated;
a deflecting device arranged between the first optical element and the focusing optics that diverts a focus position of the luminous beam;
the deflecting device comprising a first movable reflective element movable about a first axis configured to deflect the luminous beam in an X direction and a second movable reflective element movable about a second axis that is substantially orthogonal to the first axis configured to deflect the luminous beam in a Y direction;
a beam splitter, located between the deflecting device and the focusing optics; and
in which the entrance optics and focusing optics are chromatically corrected over a spectral range of selected femtosecond pulses such that the selected femtosecond pulses are focused with a dispersion induced temporal broadening of less than 30%.

US Pat. No. 10,080,493

MEASUREMENT SYSTEM AND METHOD FOR ESTABLISHING THE REFRACTION OF AN EYE, THE RADIUS OF CURVATURE OF THE CORNEA OR THE INTERNAL PRESSURE OF AN EYE

CARL ZEISS MEDITEC AG, J...

1. A method for establishing refraction of an eye by means of a refractometer, comprising:establishing an orientation of a visual axis of the eye before establishing the refraction while a patient having the eye is under general anesthesia or the eye is anesthetized in a retrobulbar fashion;
aligning the refractometer with respect to the visual axis of the eye by matching an orientation of the refractometer with the orientation of the visual axis so that a refraction measurement takes place on the visual axis of the eye; and
establishing the refraction after the alignment,
wherein the orientation of the visual axis of the eye is established based on a position of a Purkinje image of at least one light source used to illuminate the eye and a relationship between the position of the Purkinje image and the orientation of the visual axis, and
wherein the relationship between the orientation of the visual axis and the position of the Purkinje image on the eye is established during a reference measurement, the reference measurement includes determining a set of positions for a plurality of Purkinje images for a plurality of viewing directions.

US Pat. No. 9,883,804

METHOD AND DEVICE FOR EXAMINING A BIOLOGICAL TISSUE BY ANALYSING FLUORESCENCE RESPONSE TO ILLUMINATION AND FOR TREATING THE TISSUE

CARL ZEISS MEDITEC AG, J...

1. A method for examining biological tissue, wherein the method comprises:
illuminating the biological tissue to be examined by illumination radiation emitted by a light source along an illumination
optical path to cause the biological tissue to emit fluorescence radiation;

filtering the emitted fluorescence radiation by a filter positioned in an observation optical path to generate an image of
the biological tissue based on the filtered fluorescence radiation, which image is capable of at least one of (i) being observed
and (ii) being recorded and optically displayed;

the filter being a double bandpass filter comprising a combination of a longpass filter and a notch filter and having a first
passband within a wavelength range of from 460 nm to 560 nm and a second passband within a wavelength range of from 600 nm
to 685 nm, the first passband and the second passband being apart from one another by at least 60 nm.

US Pat. No. 9,855,169

METHOD FOR MARKING OF COAGULATION SITES ON A RETINA AS WELL AS A SYSTEM FOR COAGULATING THE RETINA

Carl Zeiss Meditec AG, J...

1. A system for coagulating the retina; comprising:
an imaging diagnostic unit;
a therapy beam source generating a therapy beam that coagulates coagulation sites;
a pilot beam source generating a pilot beam that marks the coagulation sites by a spot sequence;
a beam deflecting unit that generates a spot sequence and that positions the therapy beam;
a device for temperature determination that determines a temperature at the coagulation sites;
an electronic control unit that is operably coupled to and controls the imaging diagnostic unit, the therapy beam source,
the pilot beam source and the beam deflecting unit; and a software interface operably coupled to the electronic control unit;

an interactive interface operably coupled to the electronic control unit; and
an interrupter that, when activated, prevents at least one specific wavelength range of the therapy beam from impinging on
the coagulation site;

wherein the device for temperature determination determines the temperature at a selected coagulation site while the therapy
beam is directed at said selected coagulation site; and

wherein the device for temperature determination is connected to the interrupter indirectly via the control unit and the control
unit controls the interrupter such that the interrupter interrupts the therapy beam if the temperature determined at a selected
coagulation site exceeds a predetermined value, the predetermined value being selected to be wherein the retinal pigment epithelium
is coagulated without damaging the overlying photoreceptors thereby sparing the photoreceptors and at least partially preserving
light sensitivity at the selected coagulation site.

US Pat. No. 9,849,031

LASER INSTRUMENT FOR EYE THERAPY

Carl Zeiss Meditec AG, J...

1. A laser therapy instrument:
wherein the laser therapy instrument is structured for surgery on a cornea, a sclera, a vitreous body or a crystalline lens,
and is usable alternately with other instruments for eye diagnosis or eye therapy, in a common treatment area in which a patient
or a patient's eye is positioned, the common treatment area being accessible to the laser therapy instrument and the other
instruments in succession,

the laser therapy instrument comprising:
a beam conducting device including an exit lens system that conducts a therapeutic laser beam to the common treatment area,
and

a device operably coupled to the beam conducting device that moves at least a part of the beam conducting device that includes
the exit lens system, into the common treatment area prior to use of the laser therapy instrument and out of the treatment
area after the use of the laser therapy instrument, such that

the treatment area, after at least the part of the beam conducting device including the exit lens system has been moved out
of the treatment area, is freely accessible for using the other instruments;

the beam conducting device that can be moved in and out comprising a laser arm, wherein the exit lens system included in the
laser arm, proceeding from its working position at the eye, is either swiveled out of the treatment area by an angle of approximately
90 degrees along a circular arc path or moved out of the treatment area along a straight line and a circular arc path;

wherein the laser arm, when swivelled out of the treatment area, is located within an outer contour of the laser therapy instrument;
and

wherein the laser arm is adjustable in all three spatial directions X, Y and Z.

US Pat. No. 9,618,326

IMAGING SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A method of inspecting an eye, the method comprising:
operating an imaging system in one of a first mode of operation and a second mode of operation;
wherein the imaging system comprises a microscope system and an OCT system;
wherein the microscope system is configured to image an object plane onto an image plane and wherein the OCT system is configured
to generate an OCT measuring beam of OCT measuring light;

wherein the object plane is located in a region of an anterior portion of the eye in the first mode of operation, and the
object plane or an image of the object plane is located in a region of a retina of the eye in the second mode of operation;

wherein a lateral width of the OCT measuring beam at the object plane in the first mode of operation is greater than the lateral
width of the OCT measuring beam at the object plane or the image of the object plane, respectively, in the second mode of
operation.

US Pat. No. 9,568,722

ILLUMINATION DEVICE FOR AN OPTICAL VIEWING APPARATUS

Carl Zeiss Meditec AG, J...

1. A surgical microscope for viewing an eye of a patient, the surgical microscope comprising:
an observation optical unit and a main objective defining an object plane;
said observation optical unit and said main objective conjointly defining a viewing beam path;
an illumination device having a light source for generating illuminating light and illumination optics configured for imaging
said illuminating light at infinity;

said light source defining a light source plane and having a first individual light source and a second individual light source;
a deflection element arranged downstream of said illumination optic for coupling said illumination light into said viewing
beam path and toward said eye via said main objective as a beam of parallel rays so as to permit focusing of said parallel
rays beyond said object plane and within said eye;

said first and said second individual light sources being arranged in said light source plane;
said first individual light source having a first midpoint (M1);

said second individual light source having a second midpoint (M2);

said second midpoint (M2) and said first midpoint (M1) defining a vector from said second midpoint (M2) to said first midpoint (M1);

said vector defining a first axial direction (A1);

said illumination optics defining an optical axis (Z) arranged perpendicular to said light source plane and intersecting said
light source plane at an intersection point;

said first individual light source having a first extent (L1) along said first axial direction (A1);

said first midpoint (M1) being offset by an amount (?) in a positive direction along said axial direction (A1) with respect to said intersection point so as to bring said second individual light source closer to said optical axis causing
said first and second individual light sources to effect illuminations at respectively different angles with respect to said
optical axis thereby providing two types of illumination of the ocular fundus of the eye when said first and second light
sources are switched on separately; and

wherein the following relationship for said offset is satisfied: 0.1*L1???1*L1.

US Pat. No. 9,554,701

ARTICLE FOR USE IN AN OCT-METHOD AND INTRAOCULAR LENS

CARL ZEISS MEDITEC AG, J...

1. An article for use in an OCT method, the article comprising:
a solid substrate, having at least one light transmissive portion, which is light transmissive at least along a transmission
direction,

nanoparticles, which are, in the light transmissive portion, dispersed in and/or on the substrate;
wherein the nanoparticles are configured and dispersed such that the nanoparticles result in an increased extinction of the
light transmissive portion, compared to the substrate free of the nanoparticles, when measured along the transmission direction;

wherein the extinction of the light transmissive portion, measured along the transmission direction, is less than 6,
wherein the extinction is defined as a negative decadic logarithm of a ratio of an intensity of light which is transmitted
through the light transmissive portion to an intensity of light which is incident on the light transmissive portion, and

wherein the light is in a visible and/or in a near infrared wavelength range.

US Pat. No. 10,085,638

OPTICAL COHERENCE TOMOGRAPHY SYSTEM

CARL ZEISS MEDITEC, INC.,...

1. An OCT system, comprising an OCT scan module for retinal scanning, having an OCT scan beam, said system further comprising an anterior segment scan module which is attached externally to the OCT scan module for retinal scanning so as to switch between retinal scanning function and anterior segment scanning function of the OCT system;the anterior segment scan module comprising:
at least one anterior segment scan lens to focus the OCT scan beam in the anterior segment of an eye under investigation; and
a fixation target to maintain the viewing direction of the eye during anterior segment scanning.

US Pat. No. 10,004,641

OPHTHALMOLOGICAL DEVICE

Carl Zeiss Meditec AG, J...

1. An ophthalmic instrument for the application of laser radiation in an eye, including for examination and/or surgical laser treatment of a cornea and a lens of the eye, the ophthalmic instrument comprising:a femtosecond laser as a radiation source for laser radiation;
an optical entrance system;
an objective from which a beam emerges that is focused in a direction of the eye;
optical assemblies which are arranged in front of the objective as seen in a beam direction and which, in operative connection with the objective, selectively vary a focus position in a coordinate direction X,Y and Z either within a region of the cornea or within a region of the lens of the eye;
an aperture angle ? on a side of the objective facing the eye being variable by variation of a refractive power ratio within the optical entrance system and, thus, variation of a diameter of a beam emerging from the optical entrance system is also variable, the aperture angle ? being smaller when the focus is positioned in a region of the lens than when the focus is positioned in a region of the cornea.

US Pat. No. 9,757,205

WEIGHT MODULE FOR A STAND BASE FOR A SURGICAL MICROSCOPE

Carl Zeiss Meditec AG, J...

1. A weight module for a stand base for a surgical microscope, the stand base being for setting up on a floor configured as
a planar surface and the stand base including: a base body defining an underside and being configured to accommodate the weight
module; a support arrangement connected to the base body and being configured to support the stand base with at least three
support points in contact engagement with the floor to permit setting up the stand base; the support points conjointly defining
a support plane whereat the support points are in contact engagement with the floor; the underside of the base body facing
toward the support plane; an ancillary body; the base body having a receiving arrangement configured in the underside for
releasably accommodating the ancillary body; and, the underside of the base body and the support plane conjointly defining
a smallest spacing therebetween which is greater than 10 cm; the weight module comprising:
a weight module body having an upper side and an underside;
said weight module body defining a first through-hole between said upper side and said underside;
said weight module body further having a first threaded bore in said underside;
said first threaded bore extending parallel to said first through-hole;
said first through-hole defining a first through-hole central axis and a first through-hole diameter;
said first threaded bore defining a first threaded bore central axis;
said first threaded bore central axis and said first through-hole central axis defining an imaginary connecting line therebetween;
said weight module body further having a middle axis disposed on said imaginary connecting line such that a first distance
between said first through-hole central axis and said middle axis has the same value as a second distance between said middle
axis and said first threaded bore central axis; and,

said first threaded bore is configured such that said first threaded bore has an outer diameter which is smaller than said
first through-hole diameter.

US Pat. No. 9,933,606

SURGICAL MICROSCOPE

CARL ZEISS MEDITEC AG, J...

1. A surgical microscope comprising:microscopy optics;
a camera;
a display system; and
a controller;
wherein the microscopy optics are configured to image a field of view onto the camera;
wherein the camera is configured to obtain two-dimensional camera images of the field of view and to generate image data representing the camera images;
wherein the microscopy optics are variable optics configured to change an imaging scale of the imaging of the field of view onto the camera;
wherein the controller comprises a data memory storing object data of each member of a group of plural different surgical tools;
wherein the controller is configured to:
receive the image data from the camera and to process the camera images represented by the image data;
determine an expected size of a surgical tool in the camera images based on the object data of the members of the group of plural different surgical tools and the imaging scale; and
use the determined expected size of the surgical tool to identify the surgical tool in the camera images by object recognition, the object recognition including:
limiting a search space of the object recognition by using the determined expected size of the surgical tool in the camera images;
using the object data of the members of the group of plural different surgical tools and the imaging scale; and
within the limited search space, selecting, from the members of the group of plural different surgical tools, a member corresponding to the surgical tool in the camera images.

US Pat. No. 9,883,796

OPHTHALMOLOGIC SYSTEM AND METHOD OF OPERATING THE SAME

CARL ZEISS MEDITEC AG, J...

1. A method of operating an ophthalmologic system comprising an eye tracker and an OCT system, wherein the method comprises:
providing data representing a placement of a first B-scan performed on an eye relative to the eye;
performing a measurement on the eye using the eye tracker;
determining a placement of the eye relative to the ophthalmologic system based on the measurement using the eye tracker;
placing the eye relative to a reference placement of the OCT system based on the provided data and the determined placement;
performing A-scans on the eye at at least three A-scan positions, wherein the at least three A-scan positions are not arranged
on one straight line;

determining a placement of a second B-scan relative to the OCT system based on at least one of the at least three A-scans
and the provided data such that the second B-scan and the first B-scan have a substantially same placement relative to the
eye; and

generating a representation of the second B-scan,
wherein the generating of the representation of the second B-Scan comprises displaying of scattering intensities at a plurality
of locations, wherein the representation of the scattering intensity at each given location of the plurality of locations
is based on a subset of measured scattering intensities obtained by the plurality of A-scans, wherein the scattering intensities
of the subset are measured at locations having a distance from the given location smaller than a predetermined distance.

US Pat. No. 9,872,617

FLEXIBLE, MULTIMODAL RETINA IMAGE RECORDING SYSTEM AND MEASUREMENT SYSTEM

Carl Zeiss Meditec AG, J...

1. A user-interface for a device for recording multimodal retinal recordings or measurements, the user interface comprising:
a recording region and a image observation region/analysis region, wherein switching between the two regions is achieved by
a single user action;

the recording region comprising a measuring instrument control region and at least one image display region including a first
image display region;

a measuring instrument control region comprising two or more measurement recording modes each identified by a tab, in which
all measurement parameters to be specified by the user for setting each mode prior to recording, are listed;

wherein the first image display region displays images which can be used for setting a measurement mode;
wherein control elements to be operated by the user during recording or adjustment are assigned to the first image display
region; and

wherein the image observation/analysis region enables looking at an image, analyzing the image and/or comparing several images
or segments of images including fundus images or OCT images.

US Pat. No. 9,629,710

INTRAOCULAR LENS HAVING AN OPTICAL AND A HAPTIC PART, METHOD FOR MAKING AN INTRAOCULAR LENS AND METHOD FOR IMPLANTING AN INTRAOCULAR LENS INTO AN EYE

Carl Zeiss Meditec AG, J...

1. A method for implanting an intraocular lens into an eye, the intraocular lens including an optical part and a haptic, the
method comprising the steps of:
inserting the intraocular lens into a capsular bag of the eye through an opening in the capsular bag;
fastening the intraocular lens in the capsular bag via the haptic;
connecting the intraocular lens to the capsular bag via at least one fixation element while fixing the position of the intraocular
lens in the capsular bag with said fixation element; and,

fusing the capsular bag with the intraocular lens in a coagulating manner via a laser to form a fused connection after the
intraocular lens has been inserted into the capsular bag.

US Pat. No. 9,622,830

STAND BASE FOR A SURGICAL MICROSCOPE

Carl Zeiss Meditec AG, J...

1. A stand base for a surgical microscope, the stand base being for setting up on a floor configured as a planar surface and
the stand base comprising:
at least a first weight module;
a base body having an underside and a cavity that is open on the underside of said base body;
said cavity being configured to accommodate said first weight module;
a support arrangement connected to said base body and being configured to support said stand base with at least three support
points in contact engagement with said floor to permit setting up said stand base;

said support points conjointly defining a support plane whereat said support points are in contact engagement with said floor;
said underside of said base body facing toward said support plane;
an ancillary body;
said base body having a receiving arrangement configured in said underside for releasably connecting said ancillary body to
the base body outside the cavity;

said underside of said base body and said support plane conjointly defining a smallest spacing therebetween which is greater
than 10 cm; and,

said ancillary body having a hollow space configured to releasably accommodate a second weight module therein.

US Pat. No. 9,579,153

DEVICE AND METHOD FOR VITREOUS HUMOR SURGERY

Carl Zeiss Meditec AG, J...

1. A method of vitreous humor surgery using a laser system, wherein the laser system comprises a femtosecond laser and a deflection
unit for guiding the laser beam, the method comprising:
determining geometric variables of a posterior eye segment;
determining a desired incision geometry for the laser system from the geometric variables; and controlling the laser and the
deflection unit correspondingly; and

imaging a scanner mirror of the deflection unit that laterally shifts a focal position of the femtosecond laser beam with
an optical beam guidance system such that the image of the scanner mirror lies in a conjugate plane to the scanner mirror;

locating the conjugate plane at a pupil of the eye that is to be treated;
emitting femtosecond laser radiation from the femtosecond laser via the scanner mirror and the optical beam guidance system;
and

treating the eye with the femtosecond laser radiation.

US Pat. No. 9,560,965

METHOD FOR DETERMINING THE AZIMUTHAL ORIENTATION OF A PATIENT EYE AND EYE SURGICAL APPARATUS THEREFOR

Carl Zeiss Meditec AG, J...

1. An eye surgical apparatus comprising:
imaging optics for generating observation images of a patient eye; and,
a device for determining and displaying an azimuthal orientation of the patient eye with respect to a reference fixed with
respect to the patient eye;

said device including:
a visual display unit configured to simultaneously display:
a section, composed of pixels, of a captured observation image of the patient eye captured by said imaging optics;
said section containing at least one segment of a sclera and being displayed as a first rectangular image strip representing,
in polar coordinates, a first annular image segment of the captured observation image;

a reference image, composed of pixels, of the patient eye and containing said at least one segment of the sclera being displayed
as a second rectangular image strip representing, in said polar coordinates, a second annular image segment of the reference
image; and,

said first and second image strips being displayed mutually parallel to one another in a mutually adjoining manner;
an input interface configured to permit an observer to effect a linear movement of the first rectangular image strip representing
the first annular image segment of the captured observation image of the patient eye relative to the second rectangular image
strip representing the second annular image segment of the reference image whereby an azimuthal orientation of said captured
observation image relative to said reference image changes during said linear movement;

a measuring system configured to determine a change of azimuthal orientation of the captured observation image relative to
said reference image because of said linear movement;

a computer unit having a computer program for computing the center of a first circular structure of a limbus and/or of an
iris of said captured observation image and for computing the center of a second circular structure of the limbus and/or of
the iris of said reference image; and,

said visual display unit being further configured to display said pixels of said captured observation image with polar coordinates
having a center coincident with the computed center of said first circular structure and to display said pixels of said reference
image with polar coordinates in a polar coordinate system having a center coincident with the computed center of said second
circular structure.

US Pat. No. 10,194,797

METHOD FOR SELECTING AN INTRAOCULAR LENS TO BE IMPLANTED INTO AN EYE

Carl Zeiss Meditec AG, J...

1. A method for selecting an intraocular lens to be implanted into an eye with the aid of a ray tracing method, based on a simplified, centered optical system, wherein preoperatively measured biometric values, effective or actual lens position of the eye, and data is used for the ray tracing method that contain sets of input and output beams as follows:{hi:tan(?i)}m{hi:tan(?i?)}m
where hi refers to the height (distance) of the beams from an optical axis,
tan(?i) refers to the angle between the beams and the optical axis,
I refers to a number of beams on a semi-meridian, and
m refers to a number of image distances from a reference plane,
the data being based on a (known) standardized refractive index nV for a vitreous body of the eye and on an assumption that the reference plane of an equatorial plane of the intraocular lens or of an insertion plane corresponds to haptics of the intraocular lens, calculated for a standardized distance behind the equatorial plane of the intraocular lens.

US Pat. No. 10,092,179

SYSTEM FOR OPTICAL COHERENCE TOMOGRAPHY, COMPRISING A ZOOMABLE KEPLER SYSTEM

CARL ZEISS MEDITEC AG, J...

1. An optical system for examining an eye, wherein the optical system comprises:an OCT system configured to produce a measurement beam which is incident on the eye;
wherein the OCT system comprises an objective and a variable optical assembly, wherein the variable optical assembly is disposed upstream of the objective when seen relative to a light path of the measurement beam directed toward the object;
wherein the variable optical assembly has a first optical component having an optically effective entry surface, through which the measurement beam, in the light path directed toward the object, enters into the variable optical assembly and wherein the first optical component further comprises a focal plane of a principal plane of an object-side beam output of the first optical component;
wherein the variable optical assembly has a second optical component comprising an optically effective exit surface of the variable optical component, through which the measurement beam, in the light path directed toward the object, leaves the variable optical component;
wherein the variable optical assembly is configurable into a first configuration in a controllable manner, in which a focal plane position of the first optical component is situated within the variable optical assembly;
wherein the variable optical assembly is configurable into a second configuration in a controllable manner, in which the focal plane position of the first optical component is situated outside of the variable optical assembly; and
wherein the variable optical assembly is re-configurable between the first configuration and the second configuration by displacing at least one movable optical unit along the light path directed toward the object.

US Pat. No. 9,779,909

APPARATUS AND METHOD FOR GENERATING X-RAY RADIATION

CARL ZEISS MEDITEC AG, J...

1. Apparatus for generating an X-ray radiation field, comprising an electron beam source for generation of an electron beam
as well as one target for generating the X-ray radiation field by electrons of the electron beam impinging on said target
and being emitted from said target as X-ray radiation, said X-ray radiation field being formed by the entirety of the emitted
X-ray radiation from said target, characterized in that, the apparatus is designed for generating an adjustable and/or changeable
X-ray radiation field, and in that the apparatus has a variation appliance for varying at least one parameter of the electron
beam source and/or the electron beam for spatially influencing the X-ray radiation field, said variation appliance being designed
for varying parameters of the electron beam source and/or of the electron beam while the electron beam is impinging on the
target during a loop of the electron beam on said target.

US Pat. No. 10,098,784

TREATMENT APPARATUS FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT, METHOD OF GENERATING CONTROL DATA THEREFORE, AND METHOD FOR SURGICAL CORRECTION OF DEFECTIVE EYESIGHT

Carl Zeiss Meditec AG, J...

1. A system, comprising:a planning device for determining control data for a treatment apparatus for surgical correction of defective eyesight in an eye of a patient and a measurement device connected to the planning device, wherein
the measurement device generates measurement data of parameters of the eye and defective-eyesight data of the defective eyesight of the eye and supplies the data to the planning device,
the planning device generates the control data for the treatment apparatus which separates eye tissue by focusing pulsed laser radiation to target points within the eye,
wherein the planning device defines a boundary surface within eye tissue by using the measurement data and the defective-eyesight data, and
generates for said boundary surface control data to control the treatment apparatus, which the control data defines as a three-dimensional pattern of the target points in the eye, which are located in the boundary surface and are arranged such that the boundary surface is obtained as a cut surface when the pulsed laser radiation is irradiated according to the control data;
wherein the planning device and the measurement device are combined in one system; and
wherein the control data specify target points to which pulses of the pulsed laser radiation shall be emitted and wherein the treatment apparatus shifts a focus of the laser radiation along a path extending over the target points and emits pulses of the pulsed laser radiation along the path to the target points and also to intermediate points at locations which are located between the target points wherein the target points represent a subset of all points to which the pulses of the pulsed laser radiation are applied, wherein the intermediate points of a laser application are not specified target points of the control data.

US Pat. No. 9,788,718

SURGICAL MICROSCOPE

Carl Zeiss Meditec AG, J...

1. A surgical microscope for imaging structures of an eye, the surgical microscope comprising:
a front optical unit;
an adjustable camera optical unit;
the surgical microscope defining an illumination beam path extending through said front optical unit and an imaging beam path
extending through said front optical unit and said adjustable camera optical unit;

an illumination device having an illumination-radiation-emitting illumination source and being configured to illuminate the
retina of the eye with an illumination spot via said illumination beam path;

a camera;
said adjustable camera optical unit being disposed upstream of said camera with respect to said imaging beam path;
a control device configured to control said adjustable camera optical unit and set said adjustable camera optical unit so
as to cause the retina of the eye to be imaged on said camera in the region of said illumination spot;

said control device being further configured to vary a focusing state of said adjustable camera optical unit and to record
a plurality of images of the retina of the eye in the region of the illumination spot via said camera, said images being focused
in different depth planes; and,

said control device being further configured to establish a refractive value of the eye from said images.

US Pat. No. 10,213,099

METHOD FOR PRODUCING OCT IMAGES AND OTHER IMAGES OF AN EYE INCLUDING REDUCING THE INTENSITY OF REFLECTED LIGHT

Carl Zeiss Meditec AG, J...

1. A method for producing OCT images and other images of an eye, comprising:in preparation for intraocular lens implant surgery recording the OCT images and the other images of the eye simultaneously to create OCT image recordings and other image recordings captured while the eye is in a similar position;
recording the other images of anatomical structures of the eye or relating to biometric, keratometric or topographic measurements of the anatomical structures;
measuring an intensity of the other image recordings; and
lowering an intensity of reflected light reflected from the eye generated during the OCT image recordings at least by a factor of 2, as compared to the measured intensity of the other image recordings by adjustment of an illumination source or adjustment of image capture optical elements.

US Pat. No. 10,145,738

OPTICAL FILTER SYSTEM AND FLUORESCENCE DETECTION SYSTEM

Carl Zeiss Meditec AG, J...

1. An optical filter system for observing fluorescence, comprising:an illumination filter; and
a detection filter;
wherein a transmission spectrum of the illumination filter, in a wavelength range from 350 nm to 1000 nm, has
a first stopband (BS1) from 350 nm to B?1 with a mean transmittance of BTS1,
a first passband (BD1) from B?1 to B?2 with a mean transmittance of BTD1,
a second stopband (BS2) from B?2 to B?3 with a mean transmittance of BTS2,
a second passband (BD2) from B?3 to B?4 with a mean transmittance of BTD2, and
a third stopband (BS3) from B?4 to BAS with a mean transmittance of BTS3;
wherein 350 nm?B?1 wherein BTS1BTS2; BTS2BTS3;
wherein a transmission spectrum of the detection filter, in the wavelength range from 350 nm to 1000 nm, has
a first stopband (DS1) from 350 nm to D?1 with a mean transmittance of DTS1,
a first passband (DD1) from D?1 to D?2 with a mean transmittance of DTD1,
a second stopband (DS2) from D?2 to D?3 with a mean transmittance of DTS2,
a second passband (DD2) from D?3 to D?4 with a mean transmittance of DTD2, and
a third stopband (DS3) from D?4 to D?5 with a mean transmittance of DTS3;
wherein 350 nm?D?1 wherein DTS1DTS2; DTS2DTS3; and
wherein 380 nm?B?1?400 nm; 410 nm?B?2?420 nm;
425 nm?B?3?435 nm; 465 nm?B?4?485 nm; and
850 nm?B?5?1000 nm.

US Pat. No. 9,829,692

OPTICAL OBSERVATION UNIT AND METHOD FOR ENSURING AN UNCHANGING ILLUMINATION INTENSITY WHEN CHANGING THE COLOR TEMPERATURE OF THE ILLUMINATION

CARL ZEISS MEDITEC AG, J...

1. An optical observation unit comprising:
an illumination apparatus for illuminating an observation object along an illumination beam path, the illumination apparatus
having a light source emitting illumination light at a first constant intensity level with a first color temperature, and
a spectral filter apparatus that is selectively insertable into the illumination beam path, with the spectral filter apparatus
having a spectral filter with a filter characteristic so that the spectral filter converts the illumination light with the
first color temperature into illumination light at the observation object with a second color temperature that is different
from the first color temperature and so that an intensity of the light at the observation object is reduced from the first
constant intensity level to a second constant intensity level, at least one attenuator apparatus with an attenuator element
that can be inserted in the illumination beam path in place of the spectral filter apparatus, the attenuator element having
a transmission characteristic that leads to an intensity reduction of the illumination light at the observation object, wherein

the optical observation unit is configured to simultaneously insert the attenuator apparatus in the illumination beam path
when the spectral filter apparatus is taken out of the illumination beam path,

the illumination intensity reduction at the observation object caused by the spectral filter is equal to the illumination
intensity reduction at the observation object caused by the attenuator element, so that the illumination intensity at the
observation object remains constant, at the second constant intensity level, when one of the spectral filter and the attenuator
apparatus is replaced by the other of the spectral filter and the attenuator apparatus, and

one of the spectral filter and the attenuator apparatus is replaced by the other of the spectral filter and the attenuator
apparatus based on intensity level and color temperature of the light source.

US Pat. No. 9,629,537

SYSTEM FOR EYE EXAMINATION BY MEANS OF STRESS-DEPENDENT PARAMETERS

Carl Zeiss Meditec AG, J...

1. A System for examining an eye, comprising:
a microscopy system for generating an image plane image of an object region;
an OCT system, which is configured to acquire OCT data from the object region which reproduce the object region in different
stress states; and

a data processing unit which is configured to determine at least one value of a stress-dependent parameter, depending on the
OCT data;

wherein the system is configured to generate an output image, depending on the image plane image and furthermore depending
on the stress-dependent parameter,

wherein the data processing unit is furthermore configured:
to determine a tissue structure image region, depending on the OCT data, wherein the tissue structure image region represents
at least one part of a tissue structure; and

to determine the value of the stress-dependent parameter depending on the tissue structure image region determined.

US Pat. No. 10,213,103

TOPOGRAPHY MODULE FOR OPHTHALMOLOGICAL DEVICES WITH A DISTANCE-INDEPENDENT KERATOMETER AND METHOD FOR THE USE THEREOF

Carl Zeiss Meditec AG, J...

1. A topography module for ophthalmological devices that have a distance-independent keratometry measurement device having a detection beam path including including elements for distance independent keratometry measurement, elements for illumination and detection, as well as elements for control and evaluation, wherein:the topography module generates a luminous pattern, and
the topography module is disposed, in a stationary or moveable manner, in a beam path between the ophthalmological device and the eye,
wherein the topography module transmits a keratometry beam, and
includes devices that facilitate placement of the topography module at a definite position in the beam path between the ophthalmological device and the eye,
wherein an existing control unit of the ophthalmological device is adapted for controlling the topography module appropriately for generating light patterns,
wherein an existing evaluation unit is suitable for evaluating the reflected images of an eye recorded and transmitted by the detection unit in both a keratometric as well as topographic manner; and
wherein the topography module is transparent, and for generation of the light pattern necessary for topography measurements, has local light decoupling inhomogeneities in a volume thereof or structures on its surface, or an opto-electronic coating.

US Pat. No. 10,123,906

FEMTOSESCOND LASER SYSTEM FOR THE EXACT MANIPULATION OF MATERIAL AND TISSUES

CARL ZEISS MEDITEC AG, J...

1. A device for precise machining of a material, comprising:a pulsed laser system including:
a beam source having a cavity-dumped fs oscillator configured to emit a pulsed laser beam;
a beam focusing apparatus configured to focus the pulsed laser beam to a laser focus spot within the material; and
a beam deflection apparatus configured to deflect the pulsed laser beam so as to move the laser focus spot to different points within the material;
wherein the pulsed laser beam emitted by the cavity-dumped fs oscillator includes a plurality of laser pulses,
wherein the plurality of laser pulses of the pulsed laser beam emitted by the cavity-dumped fs oscillator are configured to destroy the cohesion of the material at the laser focus spot, and
wherein the beam deflection apparatus and the beam focusing apparatus are configured to move, according to a scan algorithm, the laser focus spot relatively more quickly in a first of three scan dimensions than in the other two of the three scan dimensions by rotating optical elements in the deflection apparatus.

US Pat. No. 10,330,927

OPTICAL SYSTEM AND SURGICAL MICROSCOPE

Carl Zeiss Meditec AG, J...

1. A surgical microscope comprising:an image acquisition system defining an image plane;
an optical system defining an optical beam path and being configured for imaging an object region into said image plane via said optical beam path;
said optical system including a first optical assembly mounted in said optical beam path so as to permit said optical beam path to pass therethrough;
said first optical assembly having an end facing away from said object region;
said optical system further including a second optical assembly mounted in said optical beam path at said end of said first optical assembly;
said second optical assembly being configured as a compensation system to at least partially compensate for longitudinal chromatic aberrations of said first optical assembly occurring in a wavelength range of light of 625 nm???850 nm;
said first optical assembly being configured as an achromatic system corrected for the light of a first wavelength and a second wavelength;
said first wavelength being preferably ??486 nm and said second wavelength being preferably ??656 nm;
said achromatic system including lenses made exclusively of normal or standard glasses to provide achromatization with said normal or standard glasses having chromatic aberrations for light in the near infrared and infrared which are approximately five times larger than chromatic aberrations in the visible spectral range;
the chromatic aberrations in the near infrared and infrared having a sign opposite to the sign of the chromatic aberrations in the visible spectral range; and,
said second optical assembly being an apochromat or semi-apochromat corrected for the light of said first wavelength, which is preferably ??486 nm, and for the light of said second wavelength, which is preferably ??656 nm, as well as the light of a third wavelength which is preferably ??588 nm to reduce the chromatic aberration in the near infrared and infrared of the image of the object region supplied to said image acquisition system.

US Pat. No. 10,278,809

MULTIFOCAL EYE LENS HAVING OPTICAL ZONES WHICH AT LEAST PARTLY ENCIRCLE A MAIN OPTICAL AXIS

Carl Zeiss Meditec AG, J...

1. A multifocal eye lens defining a main optical axis, the multifocal eye lens comprising:an optical part, viewed in the direction of said main optical axis (A), having a first optical side and a second optical side disposed opposite to said first optical side;
a plurality of annular optical zones formed on at least one of said first and said second optical sides;
said annular optical zones at least partially encircling said main optical axis (A);
at least a portion of said annular optical zones each including at least one main sub-zone;
a helix winding formed on at least one of said first and said second optical side and configured, in addition to said annular optical zones, as a surface structure of said optical part;
said helix winding running in an encircling direction about said main optical axis (A);
the lens having a refractive power varying in value imparted thereto via said helix winding running in said circumferential direction;
said portion of said annular optical zones each further including a phase sub-zone;
the lens having an overall refractive power; and,
further including at least one of (a) and (b):
(a) each of said main sub-zones of said portion of said annular optical zones has a main sub-zone refractive power contributing to said overall refractive power of the lens varying at least once in azimuthal direction around said main optical axis (A); and,
(b) each of said phase sub-zones of said portion of said annular optical zones has a sub-zone refractive power contributing to said overall refractive power of the lens varying at least once in azimuthal direction around said main optical axis (A).

US Pat. No. 10,151,909

SURGICAL MICROSCOPE AND METHOD FOR HIGHLIGHTING EYE LENS PIECES

CARL ZEISS MEDITEC AG, J...

1. A method for a highlighted representation of eye lens pieces in an image obtained from an eye by means of a surgical microscope, wherein the surgical microscope comprises at least one observation beam path for generating an optical image from the eye an illumination device for illuminating the eye, at least one digital camera for recording the optical image from the eye, and an image processing unit, whereinthe eye is illuminated with illumination light that contrasts the eye lens pieces with the aid of the illumination device, in order to generate an optical contrast image that contrasts the eye lens pieces as optical image from the eye by means of the observation beam path, wherein the illumination light that contrasts the eye lens pieces is light reflected from the retina and wherein the illumination light is projected at 6° or less along the optical axis of the at least one observation beam path or along the optical axis of the main objective of the microscope in order to generate an illumination of the eye lens, in which the retina is illuminated with illumination light that is then reflected from the retina in the red spectral range and thus illuminates the eye lens from the fundus of the eye with light with a wavelength of between 620 and 750 nm,
the optical contrast image is recorded by means of the at least one digital camera and converted into a digital contrast image,
locations of increased contrast are found in the digital contrast image with the aid of the image processing unit, wherein an algorithm is employed in the image processing unit, which algorithm is used to find locations of increased contrast by finding edges in the digital contrast image,
the image processing unit generates a superimposition image which represents the locations of increased contrast and which is adapted in its size at least to the optical contrast image or the digital contrast image,
the superimposition image is superimposed on at least the optical contrast image or the digital contrast image, and
at least the optical contrast image superimposed with the superimposition image or the digital contrast image superimposed with the superimposition image is output as the image obtained from the eye by means of the surgical microscope.

US Pat. No. 10,098,538

IMAGING SYSTEM

CARL ZEISS MEDITEC AG, J...

1. A system comprising an OCT system and a lens system;wherein the OCT system comprises:
an interferometer providing a measuring arm and a reference arm,
an OCT measuring beam emitter for emitting a beam of OCT measuring light,
OCT beam shaping optics disposed in a beam path of the measuring arm between the OCT measuring beam emitter and the lens system,
an OCT scanner disposed in the beam path of the measuring arm between the beam shaping optics and the lens system;
wherein the OCT beam shaping optics is configured such that the beam of OCT measuring light is focused at a beam focus, and
wherein the OCT beam shaping optics is configured to change a lateral width of a beam waist of the beam of OCT measuring light at the beam focus;
wherein the OCT beam shaping optics is configured such that before and after the changing of the lateral width, the beam of OCT measuring light is focused at a same distance from the lens system and/or at a focal plane of the lens system.

US Pat. No. 10,016,300

HANDPIECE FOR THE PHACOEMULSIFICATION OF AN EYE LENS

Carl Zeiss Meditec AG, J...

1. A handpiece for effecting a phacoemulsification of an eye lens, the handpiece comprising:a needle;
an aspiration line configured to transfer an aspiration fluid;
said aspiration line being arranged within said needle;
at least one drive element configured to vibrate and generate kinetic energy as a longitudinal wave; and,
said at least one drive element being arranged so as to cause said longitudinal wave to be coupled directly into said aspiration fluid to impart a fluid pressure thereto to effect the phacoemulsification of the eye lens via said fluid pressure.

US Pat. No. 10,189,493

CARRYING ARRANGEMENT FOR CARRYING A MEDICAL APPARATUS

Carl Zeiss Meditec AG, J...

1. A carrying arrangement for carrying an apparatus, the carrying arrangement comprising:a base carrier;
at least three roller elements arranged on said base carrier so as to enable the carrying arrangement to move with respect to a floor surface;
said at least three roller elements each being configured to be rotatable about respective axes of rotation (D);
at least one of said at least three roller elements being configured to be pivotable about a pivot axis (S) with respect to said base carrier;
said axes of rotation (D) and said pivot axis (S) extending in different directions;
at least one supporting element arranged at least indirectly on said base carrier;
the carrying arrangement defining a first position and a second position with respect to the floor surface;
said supporting element being configured to not contact the floor surface in said first position of the carrying arrangement;
said supporting element being configured to contact the floor surface in said second position of the carrying arrangement;
said second position being pivoted with respect to said first position;
the carrying arrangement being configured to have medical apparatuses fixed in position thereto;
said supporting element having an outer surface; and,
said outer surface extending in an inclined manner so as to enable at least one of a cable and a tube to be pushed upwards by said outer surface.

US Pat. No. 9,798,127

TUBE FOR A SURGICAL MICROSCOPE

Carl Zeiss Meditec AG, J...

1. A tube for a surgical microscope comprising:
a base part;
an intermediate part pivotable on said base part about a first rotational axis;
an ocular part pivotable on said intermediate part about a second rotational axis;
said base part, said intermediate part and said ocular part conjointly defining an imaging beam path passing therethrough;
said base part having a base part housing and said intermediate part having an intermediate part housing;
said intermediate part housing having a convex-shaped housing section at said second rotational axis;
said intermediate part being pivotably movable on said base part between a folded position and an unfolded position; and,
said base part housing including a housing section having a concave outer contour accommodating said convex-shaped housing
section of said intermediate part housing therein when said intermediate part is in said folded position causing said intermediate
part housing to be pivoted tightly against said base part housing.

US Pat. No. 10,426,662

LASER INSTRUMENT FOR EYE THERAPY

Carl Zeiss Meditec AG, J...

1. A laser therapy instrument:wherein the laser therapy instrument is structured for surgery on a cornea, a sclera, a vitreous body or a crystalline lines, and is used alternately with other instruments for eye diagnosis or eye therapy, in a common treatment area in which a patient or a patient's eye is positioned, the common treatment area being accessible to the laser therapy instrument and the other instruments in succession;
the laser therapy instrument comprising:
a beam conducting device including an exit lens system that conducts a therapeutic laser beam to the common treatment area; and
a device operably coupled to the beam conducting device that moves at least a part of the beam conducting device that includes the exit lens system, into the common treatment area prior to use of the laser therapy instrument and out of the treatment area after the use of the laser therapy instrument, such that the treatment area, after at least the part of the beam conducting device including the exit lens system has been moved out of the treatment area, is freely accessible for using the other instruments;
wherein the beam conducting device that can be moved into and out of the common treatment area comprises a laser arm, wherein the exit lens system included in the laser arm, proceeding from its working position at the eye, is either swiveled out of the treatment area by an angle of approximately 90 degrees along a circular arc path by a swiveling mechanism or moved out of the treatment area along a straight line and a circular arc path;
the swiveling mechanism being actuatable by a motor and being provided with a force limiting device.

US Pat. No. 10,265,541

FOR SIMPLIFIED REMOVAL OF A BALLOON APPLICATOR

CARL ZEISS MEDITEC AG, J...

1. A system comprising:a balloon applicator for irradiation of a cavity within living tissue, comprising an at least double-lumen shaft with a first lumen for introduction of a medium for filling a balloon connected to the shaft at a proximal and a distal position thereof, and with a second lumen for insertion of a radiation source, wherein
the shaft, between the proximal and the distal position, has a proximally arranged first portion and a distally arranged second portion which, in a first working state of the balloon applicator, are connected to each other and, in a second working state of the balloon applicator, are separated from each other; and
a tool comprising an outer tube and an inner core mounted movably in the outer tube, wherein the tube is configured to apply a force to a first part of the shaft and/or second part of the shaft of the balloon applicator,
wherein the tool is configured to apply a longitudinal force and/or a torsional moment in order to break a predetermined breaking point of the shaft.

US Pat. No. 10,182,719

METHOD FOR DETERMINING CORNEAL ASTIGMATISM USING OPTICAL COHERENCE TOMOGRAPHY

Carl Zeiss Meditec AG, J...

1. A method of determining refractive errors in the eye related to a sub-optimal surface shape of the anterior and/or posterior surface of the cornea, comprising:performing an OCT volume scan, one or more line scans or a combination of the OCT volume scan and the one or more line scans of an anterior segment of an eye;
detecting the anterior and posterior surfaces of the cornea from measured values through edge detection;
determining topographies of the anterior and posterior surfaces of the cornea; and determining the refractive errors from the topographies;
in astigmatic eyes, performing an OCT ring scan of the anterior segment of the eye and detecting extreme values of a curvature of the cornea from the measured values of the folded ring scan through edge detection;
detecting the extreme values as minima and maxima and determining the minima and the maxima of the OCT ring scan either manually or automatically; and
for determining the cylinder refractive powers, fitting circles onto the corneal curvatures to detect maximal and minimal refractive power of the cornea; or
for determining axes of astigmatism from the determined minima and maxima of the OCT ring scan.

US Pat. No. 10,709,326

METHOD FOR THE OPTIMIZED PREDICTION OF THE POSTOPERATIVE ANATOMICAL POSITION OF AN INTRAOCULAR LENS IMPLANTED IN A PSEUDOPHAKIC EYE

Carl Zeiss Meditec AG, J...

1. A method for optimized prediction of actual postoperative lens position (LP post) of an intraocular lens to be implanted in a pseudophakic eye, comprising:using known measurement values including corneal thickness (HHD), anterior chamber depth (VKT), eye length (AL) as well as a distance of a capsular bag equator (KSA) or lens haptic (LH) to an anterior surface of the lens (LV) for calculation; andincluding in the calculation at least one of an anatomical, postoperative position (LP an-post) of the intraocular lens (L) to be implanted, a diameter of the capsular bag or a diameter of a capsulorhexis.

US Pat. No. 10,299,674

VISUAL FIELD MEASURING DEVICE AND SYSTEM

Carl Zeiss Meditec AG, J...

1. A system, comprising:a mobile computer device comprising a display, a processor, and a memory with a program code stored therein, wherein the program code when executed on the processor, causes the processor to control the display to show light stimuli to perform a measurement of a visual field; and
an optical attachment operably connected to the display of the mobile computer device, wherein the optical attachment is configured to transfer an image with defined angle ratios shown on the display of the mobile computer device to at least one virtual hemisphere having a finite radius or in a visual field for an eye of a user as at least one virtual hemisphere having a finite radius.

US Pat. No. 10,166,073

CONTROL DATA GENERATION FOR THE EYE-SURGICAL TREATMENT OF DEFECTIVE VISION

Carl Zeiss Meditec AG, J...

1. A method for generating control data, which are adapted to control a laser device emitting laser radiation for surgically correcting defective vision of an eye by surgically altering a shape of an optical component of the eye, the method comprising:specifying a cutting surface, which is curved, has a vertex and a border and which is to be produced in the eye by application of the laser radiation from the laser device to the optical component of the eye for correcting a defective vision;
defining at least one path curve for the control data, along which a focus of the laser radiation is to be shifted by controlling the laser device according to the control data;
selecting the at least one path curve such that at least one path curve lies in the cutting surface or within a tolerance zone around the cutting surface;
further comprising, for the selection of the at least one path curve:
defining a reference plane which is at a predetermined angle to a direction of incidence of the laser radiation and defining various shifting positions between the vertex and the border of the cutting surface for the reference plane;
defining, for each shifting position several axes or semi-axes, which lie in the reference plane, are not parallel to each other and which, when viewed in a projection along a direction of incidence, in the case of axes, intersect and in the case of semi-axes, have at least one common point;
determining, for each shifting position of the reference plane, intersection points of the axes or semi-axes with the cutting surface; and
wherein the at least one path curve is fixed in that the intersection points are connected.

US Pat. No. 10,123,687

METHOD FOR OPTIMIZING THE SELECTION OF THE IOL TO BE IMPLANTED IN AN EYE

Carl Zeiss Meditec AG, J...

1. A method for optimizing selection of the IOL to be implanted in an eye, comprising:a) determining required biometric parameters of the eye;
b) using said parameters for a corresponding eye model;
c) calculating data of an IOL to be implanted, by ray tracing;
d) selecting an IOL to be implanted, on the basis of the data; and
e) repeating method steps c) and d) for further suitable IOLs;
further comprising, to optimize the method,
in method step a), optionally using different measuring methods as a function of respective biometric parameters to be determined;
in method step b), determining a corresponding patient-specific eye model using the parameters, and
in method step d), when selecting the IOL to be implanted, taking into consideration additional retinal image metrics along with the data determined;
wherein in method step a), measuring the anterior cornea surface takes place by application of directed reflection, wherein the measurement takes place by collimated projection of a discrete number of light points and a telecentric observation wherein the discrete number of points is selected from a group consisting of at least 6, 19 and more than 19.

US Pat. No. 10,653,557

OPHTHALMOLOGICAL LASER THERAPY DEVICE FOR PRODUCING CORNEAL ACCESS INCISIONS

Carl Zeiss Meditec AG, J...

1. An ophthalmological laser therapy device, comprising:a laser system that generates a pulsed laser beam;
a positioning system that spatially displaces a focal volume of the laser beam into a target region;
a control system that controls working parameters of the positioning system, working parameters of the laser system or both the working parameters of the positioning system and the working parameters of the laser system;
wherein the control system is programmed to generate a corneal access incision in corneal tissue of an eye through photodisruption, to modify the working parameters of the laser system, the working parameters of the positioning system or both the working parameters of the positioning system and the working parameters of the laser system as a function of a spatial position of the focal volume of the laser beam in the corneal tissue, such that the access incision varies in terms of width in the corneal tissue or the access incision both varies in terms of the width in the corneal tissue and is interrupted,
wherein the corneal access incision is formed as a passage or tunnel through the cornea from an outer boundary surface of the cornea to an inner boundary surface of the cornea without resection of tissue and through which a small diameter instrument may be inserted.

US Pat. No. 10,571,243

SYSTEMS AND METHODS FOR IMPROVED OCT MEASUREMENTS

CARL ZEISS MEDITEC, INC.,...

1. An optical coherence tomography (OCT) system comprising:a light source for generating a light beam to illuminate a sample;
a beam divider for separating the light beam into reference and sample arms, wherein the sample arm contains the sample to be imaged;
sample arm optics for sequentially illuminating a location in the sample with the light beam from different angles;
a detector for receiving light returning from the reference arm and the sample illuminated at each angle and generating signals in response thereto;
a processor for coherently combining the signals from the different angles to generate an image of the sample, said image having a transverse resolution that is higher than the transverse resolution achieved from the signal generated from a single angle and wherein the coherently combining involves averaging or adding complex OCT data from the different angles.

US Pat. No. 10,631,909

OPHTHALMIC SURGICAL CONTROL APPARATUS

Carl Zeiss Meditec AG, J...

1. An ophthalmic surgical control apparatus configured to be connectable to an ophthalmic surgical piezo handpiece for emulsifying an eye lens, the ophthalmic surgical piezo handpiece having a hollow needle defining a longitudinal axis and having an ultrasonic resonant frequency, the ophthalmic surgical control apparatus comprising: a frequency generator having a first and a second frequency module; said first frequency module being configured to generate a first oscillation signal having a first frequency f1 and said first oscillation signal being a sinusoidal vibration in accordance with equation y1=sin(2?f1×t); said first frequency being lower than the ultrasonic resonant frequency of the ophthalmic surgical piezo handpiece; said second frequency module being configured to generate a second oscillation signal having a second frequency f2 and said second oscillation signal being a sinusoidal vibration in accordance with equation y2=sin(2?f2×t); said second frequency being greater than the ultrasonic resonant frequency of the ophthalmic surgical piezo handpiece; a frequency generator control module configured to control said first and said second frequency modules; a superposition module configured to additively superpose said first oscillation signal and said second oscillation signal in accordance with equation yu=y1+y2 so as to generate a superposition oscillation signal having a superposition oscillation frequency; said superposition module being further configured to provide said superposition oscillation signal for operation of the ophthalmic surgical piezo handpiece; and, said ophthalmic surgical piezo handpiece containing a plurality of piezo stacks connected mechanically in series so as to permit an oscillation of said hollow needle only along said longitudinal axis.

US Pat. No. 10,548,771

DEVICE AND PROCEDURE TO TREAT PRESBYOPIA

CARL ZEISS MEDITEC AG, J...

10. A method for surgical correction of presbyopia in an eye of a patient, the method comprising:generating control data for placing, by a treatment apparatus, laser treatment spots into planned positions within peripheral lens tissue of the eye;
defining a lens volume reduction using measurement data on parameters of the eye for surgical correction of presbyopia, wherein the lens volume reduction defines an amount of shrinkage of a peripheral circle diameter of a lens of the eye sufficient to achieve a desired correction of presbyopia; and
treating the lens using at least one laser device by irradiating the eye with femtosecond pulses of laser radiation and longer pulses of laser radiation directed at the laser treatment spots, wherein the femtosecond pulses of laser radiation are configured to cause photodisruption in the peripheral lens tissue of the eye, wherein the longer pulses of laser radiation are configured to cause thermally induced tissue shrinkage in the peripheral lens tissue of the eye, and wherein the longer pulses of laser radiation have pulse lengths from the picosecond to millisecond range,
wherein the planned positions within the peripheral lens tissue are selected so as to bring about the lens volume reduction through the photodisruption and the thermally induced tissue shrinkage,
wherein the planned positions within the peripheral lens tissue include planned positions for laser treatment spots of a first treatment session and planned positions for laser treatment spots of at least one subsequent treatment session, and
wherein the planned positions for laser treatment spots of the at least one subsequent treatment session are determined based on an imaging of the eye performed after the first treatment session.

US Pat. No. 10,251,785

METHOD FOR EYE SURGERY

CARL ZEISS MEDITEC AG, J...

1. A system for producing control data for controlling a laser so as to produce at least one cutting surface in a cornea of an eye of a patient, the system comprising:a non-transitory computer readable medium having stored thereon instructions for:
establishing a cornea cutting surface based on data of a refraction correction, and
producing a control data set for actuating the laser to produce the cornea cutting surface,
wherein the cornea cutting surface is determined in such a way that it defines a lenticule,
wherein the lenticule has a geometry such that its removal from the eye of the patient will induce the refraction correction,
wherein the cornea cutting surface is also determined in such a way that it specifics cuts in the lenticule to be made prior to removal of the lenticule from the eye of the patient that facilitate dissection of the lenticule into at least (i) a transplant to be implanted into another eye of another patient and (ii) a waste component to be discarded,
wherein the transplant to be implanted into the another eye of the another patient is a partial volume of the lenticule, and
wherein the transplant has a geometry such that its implantation into the another eye of the another patient will induce a second refractive correction.

US Pat. No. 10,039,634

INTRAOCULAR LENS PROVIDED FOR IMPLANTATION INTO AN EYE AND DEVICE FOR CHANGING THE OPTICAL EFFECT OF AN IMPLANTED INTRAOCULAR LENS

Carl Zeiss Meditec AG, J...

1. An intraocular lens for implantation into an eye, comprising:a lens body having a central region, haptics for holding the intraocular lens in place within the eye after implantation, and activatable zones located outside the central region;
wherein the haptics comprise the activatable zones and each haptic comprises a root portion connecting the haptic to the lens body and the activatable zones, the root portions extending outwardly away from the lens body and a remainder of the haptic extending beyond the root portion away from the lens body;
wherein several of the activatable zones are arranged within the root portion of each haptic;
wherein the lens body comprises an optical axis;
wherein, the root portion and the activatable zones are configured such that after implantation of the intraocular lens into the eye at least one of position along the optical axis, rotation and tilt of the central region of the intraocular lens within the eye is changeable upon irradiating only at least some of the activatable zones with laser radiation; and
wherein at least some of the activatable zones comprise hygroscopic material encapsulated by a hydrophobic layer which can be perforated by the laser radiation.

US Pat. No. 10,531,985

DEVICE FOR MACHINING AN OBJECT BY APPLICATION OF LASER RADIATION

Carl Zeiss Meditec AG, J...

1. A device for treating an eye using laser radiation, comprising:an observation device having a first objective lens that images the eye, the first objective lens being configured to image the eye along a first optical path;
a treatment laser source that emits the laser radiation in femtosecond laser pulses that create photodisruption in tissues of the eye;
a laser scan device including a second objective lens that images the eye and through which the laser radiation is guided so as to scan through a sector within the eye that is intended to be treated; the second objective lens being configured to image the eye along a second optical path;
wherein the first objective lens and the second objective lens are different from each other in a size of a segment presented for observation in the images and/or in terms of their focal intercept;
further wherein, either, the patient and eye are supported by a portion of the device to be shiftable between a first eye position in which the eye is imaged along the first optical path and a second eye position wherein the eye is imaged along the second optical path or the first objective lens and the second objective lens are shiftable between a first operating position wherein the eye is imaged along the first optical path and a second operating position wherein the eye is imaged along the second optical path; and
further wherein during a first operating mode, the eye is imaged along the first optical path and in focus via the first objective lens, and during a second operating mode, the eye is imaged along the second optical path and in focus via the second objective lens.

US Pat. No. 10,440,256

SURGICAL MICROSCOPE AND METHOD IMPLEMENTED WITH THE SURGICAL MICROSCOPE

Carl Zeiss Meditec AG, J...

1. A surgical microscope comprising:a microscope imaging optical unit configured to image an object to be examined in an image plane along an optical imaging beam path passing through the microscope imaging optical unit;
a camera configured to capture an image of the object in the image plane;
an optical wavefront encoding element that is positioned or positionable in the optical imaging beam path, wherein the optical wavefront encoding element is configured to influence an imaging light wavefront in the optical imaging beam path, wherein the microscope imaging optical unit images the object to be examined in the image plane with a depth of field when the optical wavefront encoding element is not positioned in the optical imaging beam path, and wherein the microscope imaging optical unit images the object to be examined in the image plane with a reduced depth of field when the optical wavefront encoding element is positioned in the optical imaging beam path;
a computer unit configured to calculate an image with the reduced depth of field for further processing from an image of the object with the reduced depth of field captured by the camera; and
an autofocus system configured to receive data from the computer unit to automatically focus the image of the object with the reduced depth of field.

US Pat. No. 9,867,535

METHOD FOR THE RELIABLE DETERMINATION OF THE AXIAL LENGTH OF AN EYE

Carl Zeiss Meditec AG, J...

1. A method for reliable determination of an axial length of an eye by application of optical coherence tomography (OCT),
wherein the eye is aligned with a fixation mark so that the main measuring axis of the measuring instrument coincides at least
approximately with the visual axis of the eye;
the method comprising:
a) performing B-scans;
b) segmenting retinal tissue structure detected from the B-scans using one or different criteria; and
c) when possible, determining the axial lengths from the B-scans;
wherein segmentation of the retinal tissue structures carried out in method step b) using one or different criteria is used
for detection of a position of a fovea to monitor alignment of an optical axis of the measuring instrument with the visual
axis of the eye;

d) in an event that the position of the fovea lies on the optical axis of the measuring instrument, aggregating the axial
lengths categorized as correct dependent upon a determined position of the fovea or the lateral distance of the fovea from
the optical axis of the measuring instrument and ending the method and outputting a resulting axial length,

e) in an event that the position of the fovea has been determined but the position does not lie on the optical axis of the
measuring instrument, determining the lateral distance between the fovea and the optical axis of the measuring instrument,
in the case of a lateral distance within a measurement threshold measured from a visual axis of the eye, aggregating the axial
length of the A-scans at the determined position categorized as correct dependent upon the determined position of the fovea
or the lateral distance of the fovea from the optical axis of the measuring instrument, and outputting the axial length, or
if the lateral distance exceeds the measurement threshold ending the method; and

f) in an event that the position of the fovea could not be determined, presenting a corresponding warning message pointing
out the restricted reliability of the axial length measurement and possible pathological changes of tissues of the eye including
changes to the retina, lens or cornea.

US Pat. No. 10,659,752

SYSTEM FOR THE STEREOSCOPIC VISUALIZATION OF AN OBJECT REGION

CARL ZEISS MEDITEC AG, J...

10. A system for visualizing an object region, comprising:an electronic image capturing device having:
a first sensor area or a plurality of first sensor areas, and
a second sensor area or a plurality of second sensor areas,
an optical assembly having
a first optical channel configured for a first imaging beam path imaging the object region on the first sensor area or the plurality of first sensor areas of the image capturing device, and
a second optical channel configured for a second imaging beam path imaging the object region on ft the second sensor area or the plurality of second sensor areas of the image capturing device, a spectral transmission of the second optical channel differing from a spectral transmission of the first optical channel and
a microscope main objective system through which the first imaging beam path and the second imaging beam path pass,
a first image producing device configured to provide a first image of the object region, captured on the first sensor area of the plurality of first sensors areas, and a second image of the object region, captured on the second sensor area of the plurality of second sensor areas to first observer for visualization of the object region,
a second image producing device configured to visualize the object region for a second observer,
a computer unit with an image superposition stage configured to superpose the first image and the second image to form a monoscopic superposition image of the object region,
an orientation determining apparatus configured to determine an orientation of a perpendicular projection of a connecting line of eyes of a second observer into a plane perpendicular to an optical axis of the microscope main objective system, and
an image rotating stage configured to digitally rotate and window the monoscopic superposition image, and to provide an image which has been digitally rotated and windowed in relation to the superposition image to the second image producing device as an image of the object region for a monoscopic visualization of the object region, said digitally rotated and windowed image having an image edge parallel to the perpendicular projection of the connecting line of the eyes of the second observer into the object region.

US Pat. No. 10,213,339

METHOD AND DEVICE FOR PRODUCING CURVED CUTS IN A TRANSPARENT MATERIAL

Carl Zeiss Meditec AG, J...

12. An apparatus for isolating a volume of material within a cornea of an eye by producing curved cuts in the cornea, said apparatus comprising:a laser radiation source which focuses laser radiation into the cornea at a focal point and causes optical breakthroughs therein;
a scanning unit which three-dimensionally shifts the focal point, wherein the scanning unit comprises adjustable optics for shifting the focal point in one spatial direction which is parallel to a direction in which the laser radiation is applied;
a control unit which controls the scanning unit, to form the cut surface by sequential arrangement of the optical breakthroughs in the cornea; and
wherein the control unit controls the scanning unit such that the focal point is guided in two other spatial directions on contour lines of the cut, the contour lines being located in planes that are perpendicular to the first spatial direction.

US Pat. No. 10,179,069

DEVICE AND METHOD FOR PRODUCING CONTROL DATA FOR THE SURGICAL CORRECTION OF DEFECTIVE EYE VISION

Carl Zeiss Meditec AG, J...

1. A method for generating control data that control a laser for surgical correction of defective vision of an eye of a patient, wherein, prior to application of the laser to a cornea, the cornea is brought from an undeformed state to a deformed state by pressing a front surface of the cornea against a contact surface; the method comprising:a) predetermining a correction surface by application of a control unit, which correction surface relates to the cornea in the undeformed state and is to be produced for correction of defective vision as a cut surface in the cornea;
b) selecting several points lying in the correction surface or in an approximation surface derived therefrom by application of the control unit, the several points being a subset of points lying in the correction surface or the approximation surface derived therefrom;
c) generating transformed points by transforming by application of the control unit, coordinates of the selected points into coordinates of the same points for the cornea in the deformed state to compensate for the deformed state of the cornea during operation of the laser;
d) generating an interpolation surface by interpolating between the transformed points by application of the control unit; and
e) selecting target points lying on the interpolation surface by application of the control unit; and
f) using the target points for generating the control data.

US Pat. No. 10,729,586

PLANNING DEVICE FOR AN OPHTHALMIC LASER THERAPY DEVICE

Carl Zeiss Meditec AG, J...

1. A planning device for planning a scanning pattern of a closed structure to be created by control of an ophthalmic laser treatment apparatus that when operated produces the closed structure in a tissue of a patient's eye in a single-pass method, the planning device comprising:a controller processor;
memory operably coupled to the controller processor in which is encoded a selection table of scanning patterns, an algorithm for creating a scanning pattern of the closed structure or both of the foregoing;
the memory storing executable instructions that when executed cause the planning device to define a change over time in a position of a focus of a laser beam of the ophthalmic laser treatment apparatus in the tissue of the patient's eye by the scanning pattern with reference to the three spatial axes x, y, and z;
wherein the scanning pattern comprises a macroscopic scanning pattern of the closed structure to be created by control of the ophthalmic laser apparatus;
wherein the z-direction runs parallel to an optical axis of the ophthalmic laser treatment device;
wherein a starting point of the macroscopic scanning pattern of the closed structure in the tissue of the patient's eye is fixed in a region of a minimum change in the macroscopic scanning pattern in the z-direction per unit of time, or in a region in which a direction of progress of the macroscopic scanning pattern runs parallel to a direction of a maximum offset in an x-y plane by movements of the patient's eye relative to the ophthalmic laser treatment device during an ophthalmic laser treatment.