US Pat. No. 9,320,447

DYNAMIC CANCELLATION OF MRI SEQUENCING NOISE APPEARING IN AN ECG SIGNAL

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:
while imaging a patient using an initial magnetic resonance imaging (MRI) sequence, receiving an initial set of electrocardiograph
(ECG) signals from the patient;

identifying initial noise in the initial set of ECG signals arising from the initial MRI sequence;
characterizing the initial noise in terms of frequency components thereof;
generating a relation between parameters defining the initial MRI sequence and the frequency components;
computing a filter by applying the relation to the parameters of a subsequent MRI sequence; and
applying the computed filter to reduce noise in a further set of ECG signals, received from the patient, while imaging the
patient using the subsequent MRI sequence.

US Pat. No. 9,226,710

WIRELESS CATHETER WITH BASE WIRELESS TRANSCEIVER

BIOSENSE WEBSTER (ISRAEL)...

1. A medical probe, comprising:
a flexible insertion tube having a distal end for insertion into a body cavity and comprising one or more sensors mounted
in the distal end;

a handle coupled to a proximal end of the insertion tube;
a cable having a proximal end and a distal end, which is coupled to the handle so as to receive signals conveyed through the
insertion tube from the one or more magnetic field sensors; and

a base unit coupled to the proximal end of the cable, and containing:
a power source;
a probe wireless transceiver coupled to receive the signals from the cable and to communicate over a wireless connection with
a control console; and

a spherical orb configured to house the base unit, and a socket configured to retain and allow a rotation of the spherical
orb, wherein the power source is selected from a list comprising a battery, a power outlet and a wireless energy transfer
system.

US Pat. No. 9,433,464

CATHETER WITH NEEDLES FOR ABLATING TISSUE LAYERS IN VESSEL

Biosense Webster (Israel)...

1. A catheter comprising:
a catheter body;
a distal tip section having:
a tubing with a lumen, the tubing having at least one opening;
at least one needle in the lumen configured to assume a deployed position and a retracted position;
an elongated support member extending through at least the lumen of the distal tip section;
an actuator extending through at least the lumen of the distal tip section and configured for longitudinal movement on and
relative to the elongated support member,

a control handle having a member adapted to control longitudinal movement of the actuator relative to the elongated support
member; and

a wire adapted for longitudinal movement relative to at least the catheter body for moving the actuator relative to the elongated
support member;

wherein the at least one needle is supported by the elongated support member while in the retracted position and the at least
one needle is pushed outwardly in a radial direction by the actuator while in the deployed position.

US Pat. No. 9,050,011

REMOVAL OF ARTIFACTS FROM MAP DATA

Biosense Webster (Israel)...

1. A method for mapping, comprising:
receiving an initial set of measured values of a physiological parameter, which were measured at respective locations in a
body organ comprising a heart, wherein the physiological parameter comprises a local activation time of the heart;

receiving a three-dimensional (3D) map of the heart comprising an array of spatial map elements, the spatial map elements
comprising planar polygons comprising triangles having vertices corresponding to positions on a wall of the heart;

forming a correspondence between the respective locations at which the measured values were measured and a sub-group of the
map elements, wherein the sub-group comprises respective nearest triangles to the respective locations;

in response to the correspondence, associating respective element values of the physiological parameter with map elements
other than the sub-group, the map elements other than the sub-group comprising one or more adjacent triangles having a common
side with each of the respective nearest triangles, and the one or more adjacent triangles being in response to a slowness
vector associated with each of the respective nearest triangles;

adjusting the respective element values so that contiguous sets of the map elements form a geodesic; and
displaying a map of the heart showing the adjusted element values.

US Pat. No. 9,480,416

SIGNAL TRANSMISSION USING CATHETER BRAID WIRES

BIOSENSE WEBSTER (ISRAEL)...

8. A method for fabricating a probe, the method comprising:
mounting a magnetic field sensor and a dummy load adjacent to one another in an insertion tube;
adjacent to one another in an insertion tube;
placing along the insertion tube a braid comprising multiple braid wire so as to traverse a length of the insertion tube;
connecting a first pair of the braid wires across the magnetic field sensor, and connecting a second pair of the braid wires
across the dummy load; and

providing circuitry that cancels interference in a first signal transferred over the first pair of braid wires using a second
signal transferred over the second pair of braid wires.

US Pat. No. 9,414,770

RESPIRATORY EFFECT REDUCTION IN CATHETER POSITION SENSING

Biosense Webster (Israel)...

1. Apparatus for determining position and orientation coordinates of a probe within a body of a patient while compensating
for respiration of the patient, the apparatus comprising:
(i) a plurality of body-electrodes adapted for positioning in galvanic contact with a body of a patient;
(ii) a probe having at least one conductive electrode and adapted for positioning in the body of the patient; and
(iii) a control unit comprising:
(a) an alternating current driver for measuring current between the at least one conductive electrode and the plurality of
body-electrodes;

(b) a voltage driver for measuring impedance between the at least one conductive electrode and the plurality of body-electrodes;
(c) a processor, which is configured to:
(i) track position and orientation coordinates of the probe during respiration of the patient using the at least one conductive
electrode and the plurality of body-electrodes,

(ii) determine respiration indications related to impedance measured between the body-electrodes during the respiration,
(iii) calculate a function relating the tracked position and orientation coordinates of the probe to the respiration indications,
(iv) apply the function to identify end-expirium points of the respiration of the patient based on subsequent indications
related to the impedance and evaluating that the function is less than a predetermined threshold; and

(v) determine respiratory compensated position and orientation coordinates of the probe using an estimate of respiratory movement
of the probe based on the end-expirium points.

US Pat. No. 9,320,474

SYNCHRONIZING BETWEEN IMAGE SEQUENCES OF THE HEART ACQUIRED AT DIFFERENT HEARTBEAT RATES

Biosense Webster (Israel)...

1. A method for performing a medical procedure, comprising:
holding a non-linear dependence between a duration of a given phase within a cardiac cycle and a respective heartbeat rate;
receiving first and second image sequences of a dynamic activity of a heart of a patient, acquired at respective different
first and second heartbeat rates of the heart;

synchronizing between the first and second image sequences based on the non-linear dependence, on the first and second heartbeat
rates, and on a given common heartbeat rate; and

playing the first and second image sequences in synchronization with the common heartbeat rate.

US Pat. No. 9,204,820

CATHETER WITH COMBINED POSITION AND PRESSURE SENSING STRUCTURES

Biosense Webster (Israel)...

1. A catheter for use with a catheterization system having a plurality of magnetic field generators, each generating a position-data
magnetic field, the catheter comprising:
a flexible tubing; and
a distal section adapted for engagement with patient tissue, the distal section having:
a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;
a distal section magnetic field generator positioned in one of the proximal or distal portions, the distal section magnetic
field generator adapted to generate a pressure-data magnetic field;

a plurality of sensing coils positioned in the other of the proximal and distal portions;
wherein at least one sensing coil of the plurality of sensing coils is configured to sense each position-data magnetic field
and each pressure-data magnetic field and generate signals representative of data relating to a position of the distal section
and data relating to pressure exerted on the distal section when engaged with the patient tissue; and

wherein the at least one sensing coil of the plurality of sensing coils has a respective lead connected thereto configured
to transmit signals for signal processing.

US Pat. No. 9,044,156

CATHETER WITH IMPROVED SAFETY LINE FOR DISTAL TIP AND RELATED METHOD

Biosense Webster (Israel)...

1. A catheter, comprising:
an elongated catheter body;
a tip electrode distal to the catheter body, the tip electrode comprising:
a support member having a passage portion defining a rounded distal surface; and
an electrically conductive shell mounted on the support member; and
a safety tensile member having a tensile portion positioned in the passage portion to pass around the rounded distal surface.

US Pat. No. 9,433,751

STEERABLE CATHETER WITH DISTAL TIP ORIENTATION SHEATHS

Biosense Webster (Israel)...

1. A steerable catheter for contacting tissue comprising:
an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending there through;
a tip section at the distal end of the catheter body, the tip section comprising a flexible plastic tubing having first and
second pairs of diametrically-opposed lumens extending there through, wherein the first pair of diametrically-opposed lumens
is in a plane generally perpendicular to the plane containing the second pair of diametrically-opposed lumens, and a tip electrode;

a control handle at the proximal end of the catheter body;
first and second puller wires, each extending through one of the lumens of the first pair of diametrically-opposed lumens
and through the lumen of the catheter body, each having a proximal end anchored to the control handle and a distal end anchored
to the tip section, whereby the first puller wire is longitudinally moveable relative to the catheter body to cause deflection
of the tip section in a plane in a first direction and the second puller wire is longitudinally moveable relative to the catheter
body to cause deflection of the tip section in the plane in a second direction opposite the first direction;

and first and second tubular orientation sheath members each having proximal and distal ends, each comprised of a thin walled
polymide tube, each extending through one of the lumens of the second pair of diametrically opposed lumens, each having an
outer diameter substantially the same as the inner diameter of the lumen through which it extends and wherein each tubular
orientation sheath member is bonded along a substantial portion of the tubular orientation sheath member to the wall of one
of the lumens and wherein the tubular orientation sheath members are located and configured to reduce bending of the tip section
in a direction other than across the plane in which the tubular orientation sheaths are contained, thereby providing greater
contact force of the tip electrode against the tissue.

US Pat. No. 9,364,285

SEALED TWO-WAY MAGNETIC MANIFOLD

BIOSENSE WEBSTER (ISRAEL)...

1. A system, comprising:
a probe comprising a handle, the probe further comprising an insertion tube having a distal end and an insulating sheath:
an inlet tube configured to receive an irrigation fluid from a pressurized fluid source;
at least first and second outlet tubes configured to deliver the irrigation fluid to respective outlets of the device;
a manifold located within the handle containing a chamber coupled between the inlet tube and at least the first and second
outlet tubes;

a ball comprising a magnetic material contained inside the chamber; and
a magnetic field generator disposed outside the chamber and configured to generate a variable magnetic field within the chamber
so as to move the ball between at least a first position in which the first outlet tube is blocked, a second position in which
the second outlet tube is blocked, and a third position, in which neither of the outlet tubes is blocked,

a plurality of ablation electrodes, the electrodes comprising thin metal layers formed over the insulating sheath of the insertion
tube,

wherein the respective outlets are connected to respective apertures of the ablation electrodes.

US Pat. No. 9,326,818

DOUBLE LOOP LASSO WITH SINGLE PULLER WIRE FOR BI-DIRECTIONAL ACTUATION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:
an elongated tubular catheter body with at least one lumen extending there through;
a deflectable intermediate section having proximal and distal ends and at least two off-axis lumens extending there through,
the proximal end of the deflectable intermediate section being attached to a distal end of the catheter body; and

a distal assembly distal of the deflectable intermediate section, the distal assembly comprising:
a tubular structure having a generally straight proximal region attached to the intermediate section, a generally circular
main region generally transverse and distal to the proximal region;

an elongated support member extending through the generally circular main region of the distal assembly, the elongated support
member having shape memory;

a non-conductive cover over at least the main region of the distal assembly; and
at least one electrode carried on the generally circular main region of the distal assembly;
at least first and second washers at the distal end of the deflectable intermediate section, each of the first and second
washers having at least two off-axis lumens, each axially aligned with a respective off-axis lumen of the deflectable intermediate
section;

a puller wire having two proximal portions and a mid-portion transverse to the two proximal portions, each proximal portion
extending through a respective off-axis lumen of the deflectable intermediate section and a respective off-axis lumen of each
of the first and second washers, the mid-portion being distal of the first and second washers and extending between the two
off-axis lumens of the first and second washers; and

a control handle comprising a deflection mechanism adapted to act on at least one proximal portion of the puller wire anchored
in the control handle to deflect the deflectable intermediate section.

US Pat. No. 9,326,700

CATHETER DISPLAY SHOWING TIP ANGLE AND PRESSURE

Biosense Webster (Israel)...

1. A method for displaying information, comprising:
receiving a measurement with respect to an invasive probe comprising an insertion tube inside a body of a subject of at least
one probe parameter, selected from a group of parameters consisting of a bend angle of the probe and a pressure on the probe,
wherein the probe further comprises a resilient joint at a distal end of the insertion tube and a distal tip, wherein the
resilient joint comprises a spring-loaded joint configured to permit axial displacement and angular deflection of the distal
tip, and wherein the distal tip is configured to bend at the spring-loaded joint, and a magnetic position sensing assembly
located within the probe comprising coils on opposite sides of the spring-loaded joint and wherein receiving the measurement
comprises measuring the axial displacement and angular deflection of the distal tip due to engagement of tissue in the body
by the distal tip by using the magnetic position sensing assembly to sense the position of the distal tip relative to the
distal end of the insertion tube; and

responsively to the measurement, displaying an icon on a display screen representing the at least one probe parameter for
viewing by an operator of the probe, wherein displaying the icon shows both the bend angle and the pressure, the pressure
being an indication and in proportion of both the axial displacement and angular deflection of the distal tip, and wherein
the icon is articulated to show the bend angle and is colored to represent whether the pressure is within a pre-determined
pressure range.

US Pat. No. 9,131,981

CATHETER WITH HELICAL ELECTRODE

Biosense Webster (Israel)...

1. A method for producing a medical device, comprising:
creating a plurality of perforations through an outer surface of a distal portion of an insertion tube containing a lumen
and having an outer diameter, so as to provide fluid communication between the lumen and an outer surface of the insertion
tube;

cutting a metal tube into a spiral pattern to form at least one helical electrode, the helical electrode having an inner diameter
slightly smaller than the outer diameter of the insertion tube; and

after cutting the metal tube to form the at least one helical electrode, sliding said formed at least one helical electrode
over the distal portion of the insertion tube; and

affixing the at least one helical electrode to the outer surface of the distal portion of the insertion tube.

US Pat. No. 9,421,061

VENTRICULAR FAR FIELD REDUCTION

Biosense Webster (Israel)...

1. A method of far field reduction, comprising the steps of detecting peaks of a QRS complex of a cardiac electrogram;
extracting unipolar beats of an intracardiac electrogram that occur within a predetermined time interval that includes respective
detected peaks;

constructing a first mean unipolar beat by averaging the extracted unipolar beats;
cross correlating the extracted unipolar beats with the first mean unipolar beat by determining respective time-lags therebetween;
accepting ones of the extracted unipolar beats wherein a cross correlation thereof exceeds a predetermined correlation threshold;
constructing a second mean unipolar beat from the accepted unipolar beats;
determining a ventricular far field component by subtracting the second mean unipolar beat from the extracted unipolar beats;
subtracting the ventricular far field component from the intracardiac electrogram to distinguish a local component of the
intracardiac electrogram; and

controlling a medical procedure responsively to the local component.

US Pat. No. 9,402,556

COMPENSATION FOR HEART MOVEMENT IN A BODY COORDINATE SYSTEM

Biosense Webster (Israel)...

1. A method for tracking a distal end of a probe in a beating heart, the method comprising the steps of:
inserting a flexible probe into a living subject;
positioning a distal end of the probe in a beating heart of the subject at a reference site, the distal end comprising a position
sensor configured to generate position signals indicative of a position of the distal end at the reference site, and an electrode
configured to be positioned at respective sites on the beating heart to convey electrical signals from the beating heart;

establishing a valid tracking state for the flexible probe by ensuring there is no change in the position signals over a preset
number of heart beats by verifying there is substantially no change in a position of the distal end of the probe over the
preset number of heart beats;

establishing a mean position by recording position signals from the position sensor and electrical signals from the electrode
provided there is an established valid tracking state;

formulating, in response to the position signals, a first indication of a change in the mean position of the beating heart
at the reference site within the living subject;

deriving a second indication of a change in the electrical signals; and
determining, in response to the first and second indications, a new mean position of the beating heart at the reference site
and establishing a new valid tracking state.

US Pat. No. 9,380,953

HYBRID BIPOLAR/UNIPOLAR DETECTION OF ACTIVATION WAVEFRONT

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus, comprising:
electrical circuitry for recording signal data from electrodes of a probe when the probe is at a location in a heart of a
living subject, the signal data comprising a bipolar electrogram and a unipolar electrogram;

a memory for storing the signal data;
a display; and
a processor connected to the memory and operative for performing the steps of:
defining a time interval comprising a window-of-interest;
differentiating the bipolar electrogram and the unipolar electrogram with respect to time to define a differentiated bipolar
electrogram and a differentiated unipolar electrogram, respectively;

identifying peaks within the window-of-interest in the differentiated bipolar electrogram;
establishing a bipolar activity window about respective peaks, the bipolar activity window having activity bounds and comprising
a time interval of activity about the peaks in the bipolar electrogram; and

identifying an extreme negative value (?dV/dt) in the differentiated unipolar electrogram within the activity bounds, and
reporting a time corresponding to the value as a unipolar activation onset on the display;

wherein identifying an extreme negative value comprises:
defining a slope window in the unipolar electrogram that contains downward sloping intervals;
fitting respective regression lines to the downward sloping intervals;
determining a trend in the slope window, the trend having a slope;
identifying a longest monotonic downward sloping interval contained in each slope window;
making a determination that the longest monotonic downward sloping interval occupies less than 50% of its containing slope
window; and

responsive to the determination, subtracting the slope of the trend from a slope of the regression line of the longest monotonic
downward sloping interval.

US Pat. No. 9,307,927

CATHETER ENTANGLEMENT INDICATION

Biosense Webster (Israel)...

1. A method for assisting an operator of a probe in correcting, reducing or preventing over-rotation and entanglement of the
probe, comprising:
using an elongated probe having a body and a distal end and a proximal end, and a position sensor, which is coupled to the
body of the elongated probe and is configured to generate signals used for determining location and orientation coordinates
of the probe that are indicative of the rotation applied to the proximal end of the probe by an operator;

manipulating the proximal end of the probe so as to move the distal end within a body of a patient, automatically measuring
a cumulative angle of rotation that is applied by the operator to the proximal end based on the location and orientation coordinates
of the probe; and

presenting an indication of the cumulative angle of rotation of the probe on a display to the operator in order to assist
the operator in correcting, reducing or preventing over-rotation of the probe.

US Pat. No. 9,241,632

SYNCHRONIZATION OF WIRELESS CATHETERS

Biosense Webster (Israel)...

1. A system, comprising:
multiple medical probes, each of which probes is configured to acquire physiological data from a living body with which the
probe is in contact, to send the data from the probe by transmitting over a wireless channel a sequence of data packets that
are marked with respective packet numbers, to receive a synchronization signal that is broadcast to the multiple probes, and,
in response to receiving the synchronization signal, to reset the packet numbers that are assigned in the probe to subsequent
data packets in the sequence, wherein the synchronization signal does not reset an internal clock of the probes; and

a central control unit, which is configured to transmit the synchronization signal, to receive multiple respective sequences
of the data packets from the multiple probes, to time-synchronize the data transmitted in the data packets and to output the
time-synchronized data for synchronizing the subsequent data packets.

US Pat. No. 9,204,841

CATHETER WITH SERIALLY CONNECTED SENSING STRUCTURES AND METHODS OF CALIBRATION AND DETECTION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter for use with a catheterization system having a plurality of external magnetic field generators, each generating
a position-data magnetic field, the catheter comprising:
a flexible tubing; and
a distal section adapted for engagement with patient tissue, the distal section having:
a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;
an internal magnetic field generator positioned in one of the proximal or distal portions, the internal magnetic field generator
generating a pressure-data magnetic field;

a first plurality of pressure sensing coils and to second plurality of position sensing coils positioned in the other of the
proximal and distal portions, the first plurality of pressure sensing coils adapted to sense the pressure-data magnetic field
and generate signals representative of data relating to pressure exerted on the distal section when engaged with tissue, the
second plurality of position sensing coils adapted to sense each of the position-data magnetic fields and generate signals
representative of data relating to a position of the distal section;

a first lead aerially connecting at least one pair of one of the first plurality of pressure sensing coils and one of the
second plurality of position sensing coils; and

a second lead transmitting signals from the at least one pair for signal process.

US Pat. No. 9,050,105

CATHETER WITH MULTIPLE IRRIGATED ELECTRODES AND A FORCE SENSOR

Biosense Webster (Israel)...

1. A probe, comprising:
an insertion tube;
an electrode mounted on a distal end of the insertion tube, the electrode comprising a plurality of separate electrodes having
respective sets of apertures;

a force sensor mounted in the distal end, the force sensor having a central opening and being configured to measure a force
on the distal end;

tubing, passing through the central opening, and configured to supply irrigation fluid through apertures in the electrode;
respective irrigation tubes, connected to the tubing, which feed the respective sets of apertures; and
respective valves connected to the respective irrigation tubes, wherein the respective valves are able to set respective flow
rates of the irrigation fluid to the respective sets of apertures.

US Pat. No. 9,050,056

REDUCED X-RAY EXPOSURE BY SIMULATING IMAGES

Biosense Webster (Israel)...

1. A method of medical imaging, comprising the steps of:
transmitting X-ray emissions originating from a first source through a subject;
generating a first set of temporally separated images of an area of interest in the subject from the transmitted X-ray emissions;
generating a second set of temporally separated images from the area of interest in a second source;
combining the first set and the second set to produce combined images of the area of interest;
blocking the X-ray emissions from reaching the subject;
updating the second set;
combining the first set with the updated second set to produce updated combined images of the area of interest;
displaying the updated combined images; and
when a predetermined condition is satisfied, iterating the steps of updating the second set, combining the first set with
the updated second set and displaying the updated combined images, and when the predetermined condition is not satisfied discontinuing
blocking the X-ray emissions from reaching the subject, and again performing the step of generating a first set to produce
a new first set, and thereafter iterating the steps of blocking the X-ray emissions, updating, combining the first set with
the updated second set using the new first set as the first set.

US Pat. No. 9,460,563

DIFFERENTIAL MAPPING OF A BODY ORGAN

BIOSENSE WEBSTER (ISRAEL)...

1. A method for mapping a body organ, comprising:
receiving a selection of a three-dimensional (3D) map of the body organ to be displayed;
receiving a selection of a multiplicity of map elements to be incorporated into the 3D map, each map element having a graphic
attribute indicative of a local property of the body organ;

delineating a selected region of the map, so that the map is divided into the selected region and a non-selected region; and
displaying the 3D map incorporating the selection of the multiplicity of map elements while altering the graphic attribute
of the map elements specifically within the selected region.

US Pat. No. 9,314,208

BASKET CATHETER WITH MICROELECTRODE ARRAY DISTAL TIP

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
a basket electrode assembly at the distal end of the catheter body, the basket electrode assembly having proximal and distal
ends and comprising a plurality of spines, the plurality of spines comprising a plurality of electrodes, the distal end of
the basket electrode assembly comprising a substrate body and a plurality of recessed microelectrodes, the substrate body
has an outer surface and outer surfaces of the plurality of recessed microelectrodes are flush with the outer surface of the
substrate body.

US Pat. No. 9,265,574

MONITORING TISSUE TEMPERATURE WHILE USING AN IRRIGATED CATHETER

Biosense Webster (Israel)...

1. Apparatus, comprising:
a probe having a longitudinal axis, configured to be inserted into a body cavity;
an electrode connected to the probe, the electrode having a cup shape with a flat base with an outer surface and an inner
surface;

a temperature sensor fixedly connected to and protruding from the outer surface of the electrode, the temperature sensor being
thermally and electrically isolated from the electrode and configured to measure a temperature of the body cavity; and

a micro-electrode assembly, protruding from the outer surface of the electrode, the micro-electrode assembly being insulated
from the electrode, wherein the temperature sensor and micro-electrode are distributed in spaced apart relation about the
longitudinal axis.

US Pat. No. 9,204,929

BASKET CATHETER WITH DEFLECTABLE SPINE

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
an electrode assembly at the distal end of the catheter body, the electrode assembly having proximal and distal ends and comprising
a plurality of spines, the spines comprising a plurality of electrodes, each spine comprising a bowed portion carrying the
plurality of electrodes and a generally straight distal portion, the bowed portion extending at an angle of about 30 degrees
to about 80 degrees from the generally straight distal portion;

an expander having proximal and distal ends, the expander forming a longitudinal axis of the electrode assembly, the spines
being attached at their proximal ends to the distal end of the catheter body and at their distal ends to the expander;

at least one puller wire that extends through the expander, the puller wire having a distal end anchored in the expander at
a location distal of the distal end of the catheter body and proximal of the distal end of the electrode assembly; and

a control handle proximal of the catheter body, the control handle having an actuator adapted to move the at least one puller
wire,

wherein the electrode assembly has an expanded arrangement when the expander is moved proximally along the longitudinal axis
relative to the catheter body and the electrode assembly has a collapsed arrangement when the expander is moved distally along
the longitudinal axis relative to the catheter body, and

wherein the expander is adapted to deflect in at least one direction when the at least one puller wire is moved by the actuator.

US Pat. No. 9,144,460

CATHETER WITH DIRECT COOLING ON NONABLATING ELEMENT

Biosense Webster (Israel)...

1. A catheter, comprising:
an elongated catheter body;
a tip electrode distal to the catheter body, the tip electrode comprising:
a shell having a proximal neck portion and a distal chamber;
a support member having a proximal portion and a distal portion, the proximal portion of the support member being inserted
in the neck portion of the shell, and the distal portion of the support member extending into the chamber of the shell, the
proximal portion of the support member having a fluid through-hole extending through an interior of the proximal portion of
the support member; and

a fluid channel provided between the neck portion of the shell and the distal portion of the support member, the fluid channel
being on an outer surface of the distal portion of the support member and in fluid communication with the through-hole in
the interior of the proximal portion of the support member, the fluid channel and through-hole defining a fluid flow path
from the interior of the proximal portion of the support member to the fluid channel on the outer surface of the distal portion
of the support member and to the distal chamber.

US Pat. No. 9,101,333

INTEGRATIVE ATRIAL FIBRILLATION ABLATION

BIOSENSE WEBSTER (ISRAEL)...

1. A method of ablation, comprising the steps of:
defining first regions containing first locations comprising ganglionated plexi in a heart of a living subject;
inserting a probe into the heart, the probe having electrodes on a distal portion thereof;
detecting electrical activity in the heart via the electrodes;
defining second regions having second locations wherein the electrical activity exhibits a dominant frequency that is higher
than a predefined threshold;

defining third regions having third locations wherein the electrical activity exhibits complex fractionated atrial electrograms;
constructing an electroanatomical map of the heart that defines intersections of the first regions and at least one of the
second regions and the third regions;

selecting ablation sites within the intersections; and
ablating cardiac tissue at the ablation sites.

US Pat. No. 9,050,010

DOUBLE LOOP LASSO WITH SINGLE PULLER WIRE FOR BI-DIRECTIONAL ACTUATION

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated tubular catheter body with at least one lumen extending there through;
a deflectable intermediate section having proximal and distal ends and at least two off- axis lumens extending there through,
the proximal end of the deflectable intermediate section being attached to a distal end of the catheter body; and

a distal assembly distal of the deflectable intermediate section, the distal assembly comprising:
a tubular structure having a generally straight proximal region attached to the intermediate section, a generally circular
main region generally transverse and distal to the proximal region;

an elongated support member extending through the generally circular main region of the distal assembly, the elongated support
member having shape memory;

a non-conductive cover over at least the main region of the distal assembly; and
at least one electrode carried on the generally circular main region of the distal assembly;
at least one washer at the distal end of the deflectable intermediate section, the washer having at least two off-axis lumens,
each axially aligned with a respective off-axis lumen of the deflectable intermediate section;

a puller wire having two proximal portions and a mid-portion transverse to the two proximal portions, each proximal portion
extending through a respective off-axis lumen of the deflectable intermediate section and a respective off-axis lumen of the
washer, the mid-portion being distal of the washer and extending between the two off-axis lumens of the washer; and

a control handle comprising a deflection mechanism adapted to act on at least one proximal portion of the puller wire anchored
in the control handle to deflect the deflectable intermediate section.

US Pat. No. 9,247,985

TEST JIG FOR ABLATOR

Biosense Webster (Israel)...

1. An apparatus for testing and/or calibrating an ablator, comprising:
a tissue probe emulator connectable to a tissue ablator being tested, the emulator comprising:
a temperature sensor;
a thermoelectric circuit connected to the temperature sensor and operative to vary an output temperature of the thermoelectric
circuit sensed by the temperature sensor;

an electrical load configured to be adjustable in response to control signals;
electrical control circuitry connected to the thermoelectric unit and the electrical load and operative to independently apply
control signals to adjust the electrical load and the output of the thermoelectric circuit; and

an adapter, connectable to a receptacle of the ablator and coupled to convey signals emitted by the temperature sensor to
the tissue ablator and to convey an ablation energy output of the tissue ablator to the electrical load.

US Pat. No. 9,199,061

MEDICAL DEVICE CONTROL HANDLE

Biosense Webster (Israel)...

1. A control handle for a medical device having an elongated body, a distal assembly distal the elongated body, the distal
assembly having an adjustable configuration, the medical device further comprising a puller member extending through the elongated
body and the distal assembly, the control handle comprising:
a housing having an outer surface formed with a channel;
an actuator assembly comprising:
a user interface rotational dial;
a spool having a shaft body inserted through a through-hole in the housing, the spool having a drum on which the puller member
is wound;

a detent washer mounted on the shaft body, the detent washer being rotationally coupled to the user interface rotational dial
to transmit rotational movement from the user interface rotational dial to the shaft body, the detent washer having a tab
that rides in the channel to guide movement of the detent washer;

at least one friction-inducing washer mounted on the shaft body; and
a fastener mounted on the shaft body adapted to generate a compression load on the friction-inducing washer.

US Pat. No. 9,101,396

PRESSURE SENSING FOR A MULTI-ARM CATHETER

Biosense Webster (Israel)...

1. A method for operating a medical probe having a central shaft, comprising:
pressing one or more of a plurality of arms, each arm having a proximal end directly attached to the central shaft and an
unsupported distal end that extends outward from the central shaft in a cantilevered manner, with each arm having a position
transducer coupled thereto, against an intra-body surface, so as to cause the arms to exert pressure on the surface and bend
with respect to the central shaft in response to the pressure;

measuring positions of the respective position transducers coupled to the arms; and
estimating the pressure exerted by each arm on the intra-body surface in response to the measured positions, wherein estimating
the pressure comprises calculating at least one distance between at least one respective pair of the position transducers,
and estimating the pressure responsively to the distance.

US Pat. No. 9,445,725

IRRIGATED CATHETER TIP WITH TEMPERATURE SENSOR ARRAY

BIOSENSE WEBSTER (ISRAEL)...

1. A medical probe, comprising:
an insertion tube having a distal end configured for insertion into a body of a patient and containing a lumen for conveying
an irrigation fluid and an electrical conductor for conveying electrical energy;

a conductive cap attached to the distal end of the insertion tube and coupled electrically to the electrical conductor, wherein
the conductive cap has an outer surface perforated by multiple apertures and defines an inner cavity in fluid communication
with the lumen of the insertion tube so as to permit the irrigation fluid from the lumen to flow out of the cap through the
apertures and a plurality of ribs integrally constructed into an inner surface of the conductive cap; and

a plurality of temperature sensors, wherein a temperature sensor is mounted within each rib integrally formed into the inner
surface of the conductive cap in thermal communication with the outer surface and are thermally insulated from the irrigation
fluid in the inner cavity.

US Pat. No. 9,326,693

PLACEMENT OF ELECTRODES IN PROXIMITY TO THE HEART

Biosense Webster (Israel)...

1. A method, comprising:
receiving respective electrocardiograph (ECG) signals from body-surface electrodes at respective locations in proximity to
a heart of a subject;

processing the ECG signals to generate respective signal parameters thereof characteristic of positions of the body-surface
electrodes with respect to the heart by finding baselines for the signals;

generating the respective signal parameters by determining whether differences between maximum deviations from the baselines
are positive or negative;

enumerating as a first number the body-surface electrodes having a positive difference, and enumerating as a second number
the body-surface electrodes having a negative difference, wherein achieving the specified geometrical relationship comprises
the first and the second numbers differing by no more than a preset number; and

adjusting the respective locations so as to achieve a specified geometrical relationship between the body-surface electrodes
and the heart in response to the respective signal parameters.

US Pat. No. 9,248,255

CATHETER WITH IMPROVED TORQUE TRANSMISSION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter, comprising:
an elongated catheter body comprising a first tubular structure having a first central lumen, a distal end and a proximal
end; the first tubular structure having a layer of thermoplastic material,

a deflectable section having a second tubular structure having a second central lumen, and a proximal end that is distal of
the proximal end of the catheter body; the second tubular structure having a layer of thermoplastic material;

a joint between the distal end of the first tubular structure and the proximal end of the second tubular structure, the joint
including a first bracket with two first edges and a second bracket with two second edges, each bracket having at least one
receiving formation;

a beam having a generally rectangular cross-section with first and second opposing surfaces, at least a portion of the beam
extending through the joint; and

a puller wire having first and second main sections and a U-bend section between the first and second main sections, the first
and second main sections both having an end anchored in a control handle at the proximal end of the catheter body, and the
U-bend section being anchored to a distal end of the beam;

wherein the two first edges are affixed to the first surface of the beam and the two second edges are affixed to the second
surface of the beam such that the first and second brackets form a hollow body surrounding the portion of the beam, a distal
portion of the hollow body being covered by the layer of thermoplastic material of the second tubular structure, a proximal
portion of the hollow body being covered by the layer of thermoplastic material of the first tubular structure, the layers
of thermoplastic materials of the first and second tubular structures each having at least one node extending into the receiving
formation.

US Pat. No. 9,241,756

REAL-TIME PREDICTION OF STEAM-POP EVENTS DURING ABLATION

BIOSENSE WEBSTER (ISRAEL)...

1. A method for performing a medical procedure, comprising:
coupling a probe to tissue in an organ of a patient;
applying ablation energy to the tissue using the probe;
estimating a model of an evolution of steam pressure in the tissue, caused by the ablation energy, as a function of time;
predicting, based on the model, an occurrence time of a steam pop event caused by the steam pressure; and
indicating the predicted occurrence time of the steam pop event to an operator, wherein estimating the model comprises estimating
a penetration depth of the probe into the tissue, and calculating the model based on the penetration depth and the ablation
energy.

US Pat. No. 9,216,056

CATHETER FOR TREATMENT OF ATRIAL FLUTTER HAVING SINGLE ACTION DUAL DEFLECTION MECHANISM

Biosense Webster (Israel)...

1. A deflectable catheter comprising:
an elongated catheter body having an outer wall, proximal and distal ends, and at least one lumen extending therethrough;
a distal tip section comprising a flexible tubing having a proximal end and a distal end and a plurality of lumens extending
therethrough, the proximal end of the tip section being fixedly attached to the distal end of the catheter body, the distal
tip section further comprising a nitinol tube having slots formed therein; and

first and second puller wires extending through the elongated catheter body and distal tip section,
wherein the nitinol tube and the first and second puller wires are configured such that a single longitudinal movement of
either of the first and second puller wires effects both a proximal deflection in the elongated catheter body and a distal
deflection in the distal tip section.

US Pat. No. 9,091,603

TEMPERATURE SIMULATOR FOR THERMOCOUPLE-BASED RF ABLATION SYSTEM

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus for testing a tissue ablation system, comprising:
emulation circuitry connectable to an ablator module being tested, the ablator module having an adjustable radiofrequency
(RF) power output and a monitor display, the emulation circuitry comprising:

a first arm comprising a first thermocouple metallic material linked to the power output of the ablator module;
a second arm comprising a second thermocouple metallic material connected to the monitor display;
a return pathway extending from the first arm to the ablator module, the return pathway permitting passage of RF current and
blocking direct current (DC);

an adjustable voltage source producing a DC potential and connected via an output circuit across the first arm and the second
arm, the output circuit having a greater resistance to RF current than to direct current.

US Pat. No. 9,492,639

CATHETER WITH SERIALLY CONNECTED SENSING STRUCTURES AND METHODS OF CALIBRATION AND DETECTION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter for use with a catheterization system having a plurality of external magnetic field generators, each generating
a position-data magnetic field, the catheter comprising:
a flexible tubing; and
a distal section adapted for engagement with patient tissue, the distal section having:
a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;
an internal magnetic field generator positioned in one of the proximal and distal portions, the internal magnetic field generator
generating a pressure-data magnetic field;

a first plurality of pressure sensing coils and a second plurality of position sensing coils positioned in the other of the
proximal and distal portions, the first plurality of pressure sensing coils adapted to sense the pressure-data magnetic field
and generate signals representative of data relating to pressure exerted on the distal section when engaged with tissue, the
second plurality of position sensing coils adapted to sense each of the position-data magnetic fields and generate signals
representative of data relating to a position of the distal section;

a first lead serially connecting at least one pair of one of the first plurality of pressure sensing coils and one of the
second plurality of position sensing coils;

a second lead configured to transmit signals from the at least one pair to a signal processor of the catheterization system
for signal processing; and

one or more third leads connected at one end to another one of the first plurality of pressure sensing coils and/or another
one of the first plurality of position sensing coils and configured to be connected at a second end to the signal processor
of the catheterization system, wherein a sum of the second lead and the one or more third leads is less than a sum of the
first plurality of position sensing coils and the second plurality of pressure sensing coils.

US Pat. No. 9,375,269

CATHETER WITH INTEGRATED FLOW SENSOR

BIOSENSE WEBSTER (ISRAEL)...

1. An ablation apparatus, comprising:
a flexible catheter adapted for insertion into a heart of a living subject and having a distal segment and an ablation electrode
disposed at the distal segment to be brought into contact with a target tissue in the heart, the flexible catheter having
a lumen for passage of irrigation fluid therethrough to an exit from the flexible catheter at the distal segment for cooling
of the target tissue;

an ablator, operative to apply a dosage of energy to the target tissue to ablate the target tissue;
a flow processor for adjusting a flow of the irrigation fluid through the lumen;
a sensor unit, disposed in a non-contacting relationship with the irrigation fluid, comprising a heat source that delivers
heat energy to the irrigation fluid flowing in the lumen and a thermocouple disposed downstream from the heat source in a
direction of flow of the irrigation fluid for measuring a temperature of the irrigation fluid; and

a controller operative for:
energizing the heat source of the sensor unit for a predetermined time interval to create a heated pod of irrigation fluid
that propagates downstream from the heat source;

recording a departure time of the heated pod from a first location;
detecting a temperature signal from the thermocouple indicative of a change in the temperature of the irrigation fluid;
determining an arrival time of the heated pod at a second location responsively to the temperature signal;
determining a transit time of the heated pod from the first location to the second location measured by the departure time
and the arrival time; and

commanding the flow processor to adjust the flow of the irrigation fluid responsively to the transit time.

US Pat. No. 9,351,657

CARDIAC ACTIVITY VISUALIZATION WITH FREQUENCY DISCRIMINATION

Biosense Webster (Israel)...

1. A method, comprising:
measuring electrical activity at multiple points on a surface of a heart of a patient using one or more sensors attached to
a body of the patient positioned near the heart for receiving electro-cardiac signals from the heart;

percutaneously inserting a catheter into a chamber of the heart and measuring local electrical activity at multiple points
on the surface of the heart with the catheter;

tracking a position of the catheter in the heart at each of the multiple points on the surface of the heart and recording
the local electrical activity at each of the multiple points on the surface of the heart using a mapping and navigation system
operatively connected to the catheter;

receiving heart image data as well as the measured local electrical activity and the position of the catheter recorded at
each of the multiple points on the surface of the heart and user input indicative of a spectral slice selected from a frequency
band of the electro-cardiac signals from the heart by the one or more sensors attached to the body of the patient;

calculating respective levels of the electrical activity within the selected spectral slice; and
displaying the calculated levels of the electrical activity within the selected spectral slice on a 3-D map of the heart on
a display.

US Pat. No. 9,492,104

CATHETER WITH COMBINED POSITION AND PRESSURE SENSING STRUCTURES

Biosense Webster (Israel)...

1. A catheter for use with a catheterization system having a plurality of magnetic field generators, each generating a position-data
magnetic field, the catheter comprising:
a flexible tubing; and
a distal section adapted for engagement with patient tissue, the distal section having:
a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;
a distal section magnetic field generator positioned in one of the proximal and distal portions, the distal section magnetic
field generator adapted to generate a pressure-data magnetic field;

a plurality of sensing coils positioned in the other of the proximal and distal portions, at least one sensing coil of the
plurality of sensing coils being configured as a position sensing, and a least one other of the sensing coils of the plurality
of sensing coils being configured as a pressure sensor;

wherein at least one sensing coil of the plurality of sensing coils is configured to sense each position-data magnetic field
and each pressure-data magnetic field, and to generate signals representative of data relating to a position of the distal
section and data relating to a pressure exerted on the distal section when engaged with the patient tissue; and

wherein the at least one sensing coil of the plurality of sensing coils has a respective lead connected thereto configured
to transmit signals for signal processing.

US Pat. No. 9,439,722

ABLATION TARGETING NERVES IN OR NEAR THE INFERIOR VENA CAVA AND/OR ABDOMINAL AORTA FOR TREATMENT OF HYPERTENSION

Biosense Webster (Israel)...

1. An apparatus for the ablation of tissue at the target location in the abdominal aorta, inferior vena cava and/or left renal
vein comprising:
an elongated tubular body having a distal tip with a plurality of cantilevered spines disposed thereon, wherein the plurality
of spines can move from a retracted state to a free state, the spines being configured such that in the free state each spine
has a free unsupported distal end that can move independently of the elongate tubular body, and wherein in the free state
the distal end of each spine is not directly attached to the distal end of any one of the other spines; and,

an ablation element disposed on the free distal end of each spine.

US Pat. No. 9,241,633

SYNCHRONIZATION OF WIRELESS CATHETERS

Biosense Webster (Israel)...

1. A method, comprising:
disposing multiple medical probes comprising a plurality of catheters, each catheter comprising multiple electrodes to acquire
physiological data concurrently from a living body in accordance with a respective internal clock signal;

sending the data from each catheter by transmitting over wireless channels respective sequences of data packets that are marked
with respective packet numbers, the data in each data packet beginning at a predefined electrode of each catheter and continue
cycling over the multiple electrodes of each catheter according to a predefined multiplexing order;

receiving in the probes a synchronization signal that is broadcast to each catheter; and
in response to receiving the synchronization signal, resetting the packet numbers that are to be assigned in each catheter
to subsequent data packets in the respective sequences, wherein the respective internal clock signal of each probe is free-running
irrespective of the synchronization signal.

US Pat. No. 9,168,004

MACHINE LEARNING IN DETERMINING CATHETER ELECTRODE CONTACT

Biosense Webster (Israel)...

1. A method of cardiac catheterization, comprising the steps of:
inserting a probe into a heart of a living subject, the probe having an electrode;
memorizing a designation of a contact state between the electrode and a wall of the heart as one of an in-contact state and
an out-of-contact state;

while the electrode is at the wall, passing an electrical current between the electrode of the probe and another electrode;
making at least three determinations of an impedance phase angle of the electrical current;
identifying a maximum phase angle and a minimum phase angle among the determinations;
defining a binary classifier as a value that is intermediate the minimum phase angle and the maximum phase angle;
when the designation of the contact state is the in-contact state, changing the designation to the out-of-contact state when
an other of the determinations is less than the binary classifier by at least a first hysteresis factor;

when the designation of the contact state is the out-of-contact state, changing the designation to the in-contact state when
the other of the determinations is greater than the binary classifier by at least a second hysteresis factor; and

reporting the changed designation.

US Pat. No. 9,339,333

TORSION REDUCTION SYSTEM

Biosense Webster (Israel)...

1. An apparatus, comprising:
a flexible insertion tube comprising a proximal tube end and a distal tube end for insertion into a body cavity;
an electrode mounted at the distal tube end;
a first irrigation line, comprising proximal and distal irrigation line ends, contained within the flexible insertion tube,
and configured to supply irrigation fluid from the distal irrigation line end through one or more apertures in the distal
tube end;

a first electrical line contained within the flexible insertion tube and comprising a proximal electrical line end and a distal
electric line end, which is coupled to the electrode;

a slip ring unit comprising:
a stator connected to a second electrical line for connection to a console;
a rotor connected to the proximal electrical line end; and
a hollow channel extending through respective centers of the stator and the rotor along a longitudinal axis of the slip ring
unit;

a rotary joint in fluid communication with the proximal irrigation line end, and in fluid communication with the console via
a second irrigation line;

an angle sensor configured to detect torsion of the proximal irrigation line end and the proximal electrical line end; and
a drive mechanism coupled to the rotor and configured to rotate the rotor responsively based upon the torsion detected by
the angle sensor so as to reduce the torsion of the proximal irrigation line end and the proximal electrical line end.

US Pat. No. 9,308,041

LASSO CATHETER WITH ROTATING ULTRASOUND TRANSDUCER

Biosense Webster (Israel)...

1. A medical device, comprising:
an insertion shaft, having a longitudinal axis and having a distal end terminating in a distal tip adapted for insertion into
a body of a patient;

a resilient end section fixed to and extending from the distal tip of the insertion shaft, the resilient end section defining
an arc residing in a plane, the plane oriented obliquely relative to the longitudinal axis, the arc having a center of curvature
coincident with the longitudinal axis and a radius of curvature about the longitudinal axis, and which has one or more electrodes
disposed along the end section;

an ultrasound transducer, which is fixed to the distal end and is configured to image a vicinity of the arc using ultrasound
waves, the ultrasound transducer having a field of view that is inclined relative to the axis and coincides with the vicinity
of the arc when the insertion shaft is rotated about the axis; and

a rotation mechanism that is configured to rotate the ultrasound transducer about the axis independently of rotation of the
insertion shaft.

US Pat. No. 9,265,434

DYNAMIC FEATURE RICH ANATOMICAL RECONSTRUCTION FROM A POINT CLOUD

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising the steps of:
inserting a probe into a heart of a living subject, the probe having a mapping electrode;
urging the mapping electrode into contacting relationships with a tissue in plurality of regions of interest of the heart;
acquiring electrical data from respective locations in the regions of interest;
representing the locations of the electrical data as a point cloud;
reconstructing a model of the heart from the point cloud;
applying a set of filters to the model to produce a filtered volume, wherein the steps of reconstructing the model and applying
the set of filters are performed iteratively using portions of the point cloud until a stop condition is met;

segmenting the filtered volume to define components of the heart; and
reporting the segmented filtered volume, wherein at least one of the above steps is implemented in computer hardware or computer
software embodied in a non-transitory computer-readable storage medium.

US Pat. No. 9,375,163

LOCATION SENSING USING A LOCAL COORDINATE SYSTEM

Biosense Webster (Israel)...

1. An invasive medical probe for performing a medical procedure on a body of a patient, the probe comprising:
an insertion tube, having a proximal end and a distal end configured for insertion into a body of a patient; and
multiple arms extending distally from the distal end of the insertion tube, each arm having a distal tip and comprising:
a magnetic transducer; and
an adhesive element, which is configured to removably attach the distal tip to a tissue surface of a moveable organ within
the body, the adhesive element being configured to create a temporary adhesive pad for temporarily fixing the distal tip of
each arm to the tissue surface of the moveable organ for permitting the medical probe to be used to perform the medical procedure,
wherein the temporary adhesive pad is configured to allow the multiple arms and the insertion tube of the medical probe to
be removed from the moveable organ and from the body of the patient upon completion of the medical procedure.

US Pat. No. 9,333,033

DETECTION OF ABLATION ELECTRODE CONTACT WITH TISSUE

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:
delivering a Radio Frequency (RF) signal having a time-varying power from an intra-body probe to tissue in a vicinity of the
probe in order to ablate the tissue;

measuring a temperature in the vicinity of the probe; and
deciding whether the probe is in contact with the tissue by comparing the measured temperature to a temperature threshold
that varies in time depending on the time-varying power of the RF signal by setting the temperature threshold depending on
a fourth root of the power of the RF signal and setting a proportion coefficient between the measured temperature and the
fourth root of the power of the RF signal, based on a first coefficient that links the measured temperature and the fourth
root of the power when the probe is in contact with the tissue, and a second coefficient that links the measured temperature
and the fourth root of the power when the probe is not in contact with the tissue.

US Pat. No. 9,314,299

FLOWER CATHETER FOR MAPPING AND ABLATING VEINOUS AND OTHER TUBULAR LOCATIONS

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter adapted for use in a tubular structure at or near a heart, comprising:
an elongated catheter body having a proximal end, a distal end and at least one lumen extending longitudinally therethrough;
a distal assembly distal of the catheter body and comprising at least two spines, each spine having a free distal end and
a proximal end that is affixed to the catheter body, wherein each spine comprises a distal tip electrode, at least one ring
electrode and a dedicated irrigation pathway, at least one of the distal tip electrode and the at least one ring electrode
being adapted for irrigation;

a main irrigation pathway extending through the catheter body and being adapted to introduce irrigation fluid to outside the
catheter in a region between the spines; and

wherein each spine has a support arm adapted to support the spine in a generally L-shaped configuration such that the free
distal end of each spine is positioned radially outwardly from the proximal end when the spine is in a neutral state, and
in a generally U-shaped configuration such that the tip electrode and the at least one ring electrode of each spine are simultaneously
in contact with tissue of the tubular structure upon exertion of a contact force on the distal assembly by the tubular structure,
wherein in the U-shaped configuration the distal tip electrode of each spine defines an angle with the proximal end of the
corresponding spine of about 90 degrees to about 135 degrees.

US Pat. No. 10,034,707

CATHETER WITH IRRIGATED TIP ELECTRODE WITH POROUS SUBSTRATE AND HIGH DENSITY SURFACE MICRO-ELECTRODES

Biosense Webster (Israel)...

1. A catheter comprising:an elongated catheter body;
a distal electrode member distal of the catheter body and having a porous substrate and a plurality of surface electrodes on portions of an outer surface of the porous substrate, the porous substrate having an interior chamber adapted to receive conductive fluid;
a plurality of electrode lead wires, each having a distal end connected on an outer surface of the porous substrate to a respective one of the surface electrodes and a proximal end extending through the catheter body, at least one of the plurality of electrode lead wires having its distal end connected to a first one of the plurality of surface electrodes and a portion extending underneath and insulated from a second one of the plurality of surface electrodes; and
a chamber lead wire having a distal portion extending into the interior chamber, the chamber lead wire adapted to electrify the conductive fluid in the interior chamber,
wherein the porous substrate is adapted to pass the conductive fluid from the interior chamber to the outer surface of the porous substrate.

US Pat. No. 9,468,407

CATHETER WITH DISTAL SECTION HAVING SIDE-BY-SIDE LOOPS

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body;
a distal section distal of the elongated catheter body, the distal section having a flexible elongated member with shape memory,
the member being configured to assume a 2D configuration resembling an infinity symbol and terminating in a free distal end;
and

at least one electrode mounted on the member.

US Pat. No. 9,174,023

UNIDIRECTIONAL CATHETER CONTROL HANDLE WITH TENSIONING CONTROL

Biosense Webster (Israel)...

15. A catheter, comprising:
an elongated catheter body;
an intermediate deflectable section; and
a control handle proximal of the catheter body, the control handle having:
a housing and a piston, the piston having a thumb control, the housing and the piston configured for longitudinal movement
relative to each other by a user via the thumb control for deflecting the intermediate section;

an adjustment assembly including:
a set screw configured for a frictional engagement with the piston;
a knob mounted on the housing and rotatably coupled to the set screw, the knob being rotatable in one direction to increase
the frictional engagement and rotatable in an opposite direction to decrease the frictional engagement; and

at least one rotational guide provided on the housing, the knob having at least one pin engaging the at least one rotational
guide, the at least one rotational guide being configured to limit rotation of the knob,

wherein the housing has a bore receiving a distal portion of the set screw and the at least one rotational guide extends partially
around the bore,

wherein increasing the frictional engagement locks the piston and the housing in a desired position and decreasing the frictional
engagement unlocks the piston and the housing and allows repositioning of the piston and the housing relative to each other.


US Pat. No. 9,539,056

CATHETER WITH MULTIPLE IRRIGATED ELECTRODES AND A FORCE SENSOR

Biosense Webster (Israel)...

1. A probe, comprising:
an insertion tube;
a distal electrode mounted on a distal end of the insertion tube;
a force sensor mounted in the distal end, the force sensor having a joint and a central opening and being configured to measure
a force on the distal end;

a proximal electrode mounted proximal to the joint of the force sensor;
first tubing, running from a proximal end of the insertion tube to the distal end, passing through the central opening, and
configured to supply irrigation fluid through apertures in the distal electrode; and

second tubing, running from a proximal end of the insertion tube, entering the central opening, and configured to supply irrigation
fluid through apertures in the proximal electrode.

US Pat. No. 9,486,272

FORCE FEEDBACK DEVICE AND METHOD FOR CATHETERS

Biosense Webster (Israel)...

1. An ablation apparatus, comprising:
a flexible probe adapted for insertion into a heart of a living subject and having a distally disposed ablation electrode
to be brought into contact with a target tissue in the heart, wherein the probe is operative for making a measurement of a
contact force between the probe and the target tissue;

a power source, controlled by an operator, and operative to apply a dosage of energy via the ablation electrode to the target
tissue to ablate the target tissue;

a transmitter, operative to transmit an indication of the measurement of the contact force; and
a wearable device having a receiver for receiving signals from the transmitter and an actuator operatively connected to the
receiver and operative to haptically stimulate the operator responsively to the signals such that the degree of the haptic
stimulation experienced by the operator correlates to the amount of the contact force, wherein the haptic stimulation is a
vibration with a periodicity, and the period correlates with the contact force.

US Pat. No. 9,358,061

IRRIGATED CATHETER WITH FLUID EVACUATION

BIOSENSE WEBSTER (ISRAEL)...

1. An ablation catheter for use with a suction source comprising:
an elongated catheter body;
a distal section distal the catheter body, the distal section comprising:
a tip electrode adapted for ablation and irrigation;
a multi-lumened member extending between the catheter body and the tip electrode, the multi-lumened member having a first
lumen and a second lumen;

at least one dedicated evacuation port in the tip electrode or in a sidewall of the multi-lumened member, the at least one
evacuation port being in suction communication with the first lumen; and

at least one dedicated irrigation port in the tip electrode in fluid communication with the second lumen; and
a fluid evacuation path extending at least through the catheter body and the first lumen, the fluid evacuation path configured
to provide suction communication between the suction source and the at least one dedicated evacuation port.

US Pat. No. 9,352,134

SEGMENTED BALLOON CATHETER

BIOSENSE WEBSTER (ISRAEL)...

1. A medical apparatus, comprising:
a catheter having an elongated shaft and a distal portion, the distal portion comprising an inflatable assembly,
wherein the inflatable assembly comprises a containment chamber having an outer wall, an outer surface, an axial core and
a plurality of longitudinally oriented partitions extending from the axial core to the outer wall to divide the containment
chamber into at least four inflatable sectors, the sectors being externally delimited by respective bounding portions of the
outer surface, the outer surface having perforations formed therethrough;

hydraulic valves connected to respective sectors to enable selective inflation of diametrically opposed sectors by a fluid
when the valves are connected to a source of the fluid;

at least one surface electrode mounted on each of the bounding portions, the at least one surface electrode being deformable,
the at least one surface electrode being adapted to receive an electric current and ablate a portion of a heart chamber wall;
and

a tip electrode disposed on the catheter distal to the inflatable assembly, the tip electrode adapted to provide measurements
and further adapted to ablate a portion of a heart chamber wall, and

a control processor operative to control the valves,
wherein the apparatus is adapted to provide verification of electrical contact between the heart chamber wall and electrodes
of diametrically opposed sectors.

US Pat. No. 9,278,187

METHOD FOR MAKING A LOW OHMIC PRESSURE-CONTACT ELECTRICAL CONNECTION BETWEEN SPLIT RING ELECTRODE AND LEAD WIRE

BIOSENSE WEBSTER (ISRAEL)...

1. A method for attaching a split ring electrode to a tubing of a catheter, comprising:
providing a tubing with at least one lumen, a side wall and at least one opening in the side wall providing communication
between the at least one lumen and outside the tubing;

passing an electrode lead wire through the at least one lumen and out of the at least one opening to expose a distal portion
of the electrode lead wire;

positioning the distal portion of the electrode lead wire on an outer surface of the tubing;
mounting a split ring electrode on the outer surface of the tubing covering the opening and the distal portion of electrode
lead wire; and

providing a dry film of an electrically-conductive adhesive between the ring electrode and the outer surface of the tubing;
and

heating the dry film of the electrically-conductive adhesive to reflow.

US Pat. No. 9,433,752

CATHETER WITH FLAT BEAM DEFLECTION IN TIP

Biosense Webster (Israel)...

1. A catheter, comprising:
an elongated catheter body comprising a first tubular structure having a first central lumen, a distal end and a proximal
end;

a deflectable section having a second tubular structure having a second central lumen, a distal end, and a proximal end that
is distal of the proximal end of the catheter body;

a flat beam having first and second opposing surfaces, a distal end and a proximal end;
the flat beam extending through at least the second central lumen of the deflectable section, the flat beam defining a first
sub-lumen and a second sub-lumen;

a puller wire configured with first and second puller wire segments and a U-bend puller wire segment therebetween, the U-bend
puller wire segment being anchored to the distal end of the flat beam, the first puller wire segment extending through the
first sub-lumen and through the first central lumen of the catheter body, the second puller wire segment extending through
the second sub-lumen and through the first central lumen of the catheter body;

a first compression coil surrounding a portion of the first puller wire segment extending through the catheter body, a second
compression coil surrounding a portion of the second puller wire segment extending through the catheter body;

a pair of first and second half-cylindrical brackets, the first half-cylindrical bracket comprising a first inwardly-extending
flange mounted on the first opposing surface of the beam, the second half-cylindrical bracket comprising a second inwardly-extending
flange mounted on the second opposing surface of the beam, the first and second half-cylindrical brackets forming a hollow
body generally surrounding the beam at or near a junction between the catheter body and the deflectable section, wherein the
distal end of the first tubular structure covers a proximal portion of the hollow body and the proximal end of the second
tubular structure covers a distal portion of the hollow body, and wherein the first and second inwardly-extending flanges
extend into a lumen generally defined by the pair of first and second half-cylindrical brackets.

US Pat. No. 9,498,147

ENHANCED ECG CHART PRESENTATION

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:
receiving first data samples of electrical potentials produced by a heart at a sequence of sampling times, wherein the first
data samples are collected from body surface electrodes;

receiving second data samples of ancillary data with respect to the heart at the sampling times, wherein the second data samples
are collected by one or more sensors contained within a distal end of a flexible probe inserted into the heart; and

generating, based on the first and second data samples, a trace of the electrical potentials collected at the sampling times,
the trace having a pseudo-three-dimensional (pseudo-3D) characteristic that varies responsively to the ancillary data collected
at each of the sampling times, the trace comprising a ribbon chart having a ribbon including a first line and a second line
following a contour of the first line, the first and second lines defining a depth along a pseudo-depth ancillary data axis
of the ribbon chart.

US Pat. No. 9,474,850

LASSO CATHETER WITH GUIDE WIRE

BIOSENSE WEBSTER (ISRAEL)...

1. Medical apparatus, comprising:
a flexible insertion shaft, having a proximal end and a distal end, which is adapted for insertion into a body of a patient;
a resilient end section, which is fixed to the distal end of the insertion shaft and is formed so as to assume, when unconstrained,
an arcuate shape;

one or more electrodes, which are disposed at respective locations along the end section and have perforations therein;
a first lumen, which runs from the insertion shaft through the end section so as to convey an irrigation fluid from the proximal
end of the insertion shaft to exit the end section through the perforations of the electrodes;

a second lumen, which runs through the insertion shaft to a distal opening at the distal end of the insertion shaft, and is
configured to permit a guide wire to pass through the second lumen from the proximal end of the insertion shaft to exit distally
through the distal opening, while conveying the irrigation fluid from the proximal end through the distal opening together
with the guide wire; and a manifold, which is coupled to supply the irrigation fluid from a single fluid source to both of
the first and second lumens.

US Pat. No. 9,439,727

PRE-FORMED CURVED ABLATION CATHETER

Biosense Webster (Israel)...

1. Medical apparatus, comprising:
a magnetic field generator configured to generate a magnetic field within a body of the patient;
a sheath, which has a longitudinal axis and a distal opening and is adapted for insertion through a body passage into a cavity
within the body of the patient, the cavity being defined by a wall;

a catheter, which is configured for insertion through the sheath into the cavity, the catheter being without use of any active
steering mechanism therein, the catheter comprising a resilient distal end having a resilient member, the resilient distal
end being pre-formed in a curved shape and terminating in a distal tip, the curved shape consisting of a single arcuate segment
and being contained only within the distal end of the catheter and formed so that, when unconstrained, the distal end bends
away from the longitudinal axis in the curved shape having a known bend angle, and when subjected to a force caused by the
distal tip against the wall, the distal end straightens toward the longitudinal axis reducing the bend angle, the catheter
further comprising a first and a second magnetic position transducer, wherein the first magnetic position transducer is positioned
proximal the resilient distal member and the second magnetic position transducer is positioned distal the resilient distal
member and near the distal tip of the resilient distal end, and wherein the first and the second magnetic position transducer
are each configured to sense the magnetic field and generate signals in response thereto; and

a console configured to receive and process the signals and determine the location and orientation of the first and the second
magnetic position transducers, respectfully, wherein the difference between the location and orientation of the first magnetic
position transducer and the second magnetic position transducer indicates the bend angle of the distal end of the catheter,
and wherein the reduction of the bend angle when the catheter is unconstrained is indicative of the radial force exerted on
the resilient distal tip against the wall of the body cavity, the console being further configured to provide an indication
of the bend angle to an operator of the medical apparatus so that the operator can control the radial force exerted by the
resilient distal tip against the wall of the body cavity.

US Pat. No. 9,474,466

LOW-PROFILE LOCATION PAD FOR MAGNETIC-BASED INTRA-BODY PROBE TRACKING SYSTEM

BIOSENSE WEBSTER (ISRAEL)...

1. A location pad arrangement:
the location pad arrangement comprising a location pad, a body probe, and a control console:
wherein the location pad comprises a housing, the housing comprising at least one flat surface;
the location pad further comprising at least five field generators fixed to the housing, the at least five field generators
being configured to generate respective magnetic fields having respective axes that are perpendicular to the flat surface
of the location pad;

wherein a plurality of the at least five field generators are each individually surrounded by a respective concave trench,
and wherein the trench is at least partially filled with elastic material, the elastic material therefore surrounding respective
field generators, and being adapted to dampen frequency resonances;

wherein the at least five field generators are spaced in two different dimensions with respect to the flat surface of the
location pad such that the at least five field generators are not all arranged in a straight line;

wherein the location pad comprises a plurality of substantially rigid, planar, parallel rows;
wherein the at least five field generators are distributed among the plurality of rows, with at least some of the plurality
of rows each holding a plurality of field generators;

wherein the rows are capable of pivoting with respect to other adjacent rows such that the plurality of rows of the location
pad can collectively form a concave surface;

wherein the body probe is a tool for inserting into a patient, and comprises a position sensor, the position sensor being
capable of generating electrical signals in response to magnetic fields generated by the at least five field generators; and

wherein the control console is operatively linkable to the location pad and to the body probe, and is adapted to determine
a position of the position sensor based on electrical signals received from the position sensor.

US Pat. No. 9,703,317

DONGLE WITH SHAPE MEMORY

Biosense Webster (Israel)...

1. A dongle for coupling an electrophysiologic catheter and a navigational system, including a patient interface unit (PIU),
the dongle comprising:
a body with a first electrical interface unit configured for connection to a proximal end of a control handle at a proximal
end of the catheter; and

a support portion with a second electrical interface unit configured for connection to the patient interface unit, the support
portion having an outer flexible tubular member with shape memory and first and second ends, the outer flexible tubular member
terminating at its first end in the second electrical interface unit and terminating at its second end in the body, the outer
flexible tubular member configured to simultaneously bend in multiple directions; and

a printed circuit board housed in the body and hardwired to the first electrical interface unit and the second electrical
interface unit, the printed circuit board configured to process electrical signals received from the catheter via the first
electrical interface unit.

US Pat. No. 9,629,570

TRACKING OF CATHETER FROM INSERTION POINT TO HEART USING IMPEDANCE MEASUREMENTS

Biosense Webster (Israel)...

1. A method of catheterization, comprising the steps of:
creating a subject-specific skeletal model of a body of a subject;
in the model defining an intended path of a probe within the body that leads from a point of insertion of the probe to a target;
inserting the probe into the body, wherein the probe comprises at least one electrode;
passing electrical currents through the body between the at least one electrode and respective electroconductive location
pads that are disposed at a plurality of locations on a surface of the body, wherein the plurality of locations are distributed
along the intended path of the probe, the location pads having operating volumes, the location pads being deliberately arranged
so that the operating volumes of immediately neighboring pads overlap;

measuring respective characteristics of the currents passing through the plurality of locations; and
while inserting the probe iteratively determining position coordinates of the probe responsively to the measured characteristics;
in the model tracking an actual path of the probe using the iteratively determined position coordinates; and
determining whether the actual path corresponds to the intended path,
wherein creating a subject-specific skeletal model comprises:
applying a hand-held probe to respective landmarks on the body, the hand-held probe comprising a magnetic sensor;
applying a magnetic field to the magnetic sensor;
receiving signals from the magnetic sensor responsively to the magnetic field;
computing respective positions of the landmarks responsively to the signals; and
including the positions of the landmarks as reference locations in the model,
wherein at least one of the conductive pads is a multi-location pad having a plurality of location pad units,
wherein all the location pads are connected to an enhanced active current location (ACL) system,
wherein a respective set of calibration currents is generated between the at least one electrode and the catheter at different
positions in a region of interest,

wherein a respective relation is derived for each position between the respective set of the calibration currents and the
different positions, and is used in determining the location of the probe in response to the different respective relations
and probe currents

wherein, during insertion of the probe, the ACL subsystem processes data derived from selected location pad units, wherein
said selected location pad units are those whose operating volumes include or are proximate the current location of the distal
end of the probe and wherein distant pad units are ignored,

wherein accuracy of the ACL subsystem is enhanced by correlating impedance measurements taken from the multi-location pad
with location information provided by the magnetic sensor, and

wherein the ACL subsystem is calibrated to conform to the position as computed from data supplied by the magnetic sensor.

US Pat. No. 9,576,107

MODEL BASED RECONSTRUCTION OF THE HEART FROM SPARSE SAMPLES

BIOSENSE WEBSTER (ISRAEL)...

20. A method, comprising the steps of:
defining, by a computer processor, a parametric model representing a shape of a portion of a heart;
constructing, by the computer processor, a statistical prior of the shape from a dataset of other instances of the portion,
wherein constructing the statistical prior comprises preparing segmented data meshes;

fitting, by the computer processor, the parametric model to the statistical prior by computing anatomic features from the
data meshes and computing correlation coefficients among different ones of the anatomic features, wherein computing correlation
coefficients comprises using a joint distribution model;

inserting a probe into a living subject, the probe having a mapping electrode;
urging the mapping electrode into contacting relationships with tissue in a plurality of locations in the portion of the heart
of the subject;

acquiring electrical data from the respective locations;
relating the electrical data to the fitted parametric model to produce an isosurface of the portion of the heart of the subject;
and

reconstructing the shape of the portion of the heart of the subject responsively to relating the electrical data.

US Pat. No. 9,486,282

BASKET CATHETER WITH DEFLECTABLE SPINE

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
an electrode assembly at the distal end of the catheter body, the electrode assembly having proximal and distal ends and comprising
a plurality of spines, the spines comprising a plurality of electrodes;

an expander having proximal and distal ends, the expander forming a longitudinal axis of the electrode assembly, the spines
being attached at their proximal ends to the distal end of the catheter body and at their distal ends to the expander;

at least one puller wire that extends through the expander, the puller wire having a distal end anchored in the expander at
a location distal of the distal end of the catheter body and proximal of the distal end of the electrode assembly; and

a control handle proximal of the catheter body, the control handle having an actuator adapted to move the at least one puller
wire,

wherein the electrode assembly has an expanded arrangement when the expander is moved proximally along the longitudinal axis
relative to the catheter body and the electrode assembly has a collapsed arrangement when the expander is moved distally along
the longitudinal axis relative to the catheter body, and

wherein the expander is adapted to deflect in at least one direction when the at least one puller wire is moved by the actuator.

US Pat. No. 9,592,091

ABLATION CATHETER FOR VEIN ANATOMIES

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated body;
a distal section having an electrode assembly, the electrode assembly including:
an electrode structure biased into a predetermined generally T-shape in an undeformed state that includes:
a generally linear distal portion having a first predetermined length sufficient to span an ostium of a pulmonary vein, the
generally linear distal portion being generally perpendicular to a longitudinal axis of the elongated body;

a generally linear proximal portion having a second predetermined length lesser than the first predetermined length and being
generally perpendicular to the longitudinal axis of the elongated body;

a U-shaped portion between the generally linear distal portion and the generally linear proximal portion;
an elbow connecting portion proximal of the generally linear proximal portion, wherein the generally linear distal and proximal
portions, the U-shaped portion, and the elbow connecting portion generally lie within a single common plane; and

at least two ring electrodes on the generally linear distal portion; and
a control handle proximal of the elongated body.

US Pat. No. 9,848,794

CATHETER WITH IMPROVED SAFETY LINE FOR DISTAL TIP AND RELATED METHOD

Biosense Webster (Israel)...

1. A catheter, comprising:
an elongated catheter body;
a tip electrode distal to the catheter body, the tip electrode comprising:
a support member having a passage portion defining a rounded distal surface; and
an electrically conductive shell having a proximal opening, the support member comprising a plug portion situated in the proximal
opening of the shell, a hollow proximal portion proximal the plug portion and extending into the catheter body, and a distal
portion distal the plug portion and extending into the proximal opening of the shell; and

a safety tensile member having a tensile portion positioned in the passage portion to pass around the rounded distal surface.

US Pat. No. 9,668,704

METHOD AND DEVICE FOR VISUALLY ASSISTING AN ELECTROPHYSIOLOGICAL USE OF A CATHETER IN THE HEART

BIOSENSE WEBSTER (ISRAEL)...

1. A method for visually supporting an electrophysiology catheter application in a heart of a patient by correlating a 3D
surface profile created using 3D image data recorded before the electrophysiology catheter application, with 3D mapping data
from a catheter, comprising:
(1) before initiating the electrophysiology catheter application, recording 3D image data for a body region comprising at
least part of the heart, the 3D image data being collected using one of computerized tomography (CT) and magnetic resonance
tomography (MR);

(2) extracting at least a portion of the heart from said 3D image data, the extracting process comprising segmentation of
the 3D image data, and deriving a 3D surface profile comprising at least an area of the heart to be treated from the 3D image
data;

(3) after recording the 3D image data, initiating the electrophysiology catheter application with a catheter being inserted
into the heart, and a tip of the catheter being moved into contact with a series of different points on surfaces inside the
heart including surfaces in the area of the heart to be treated;

wherein the electrophysiology catheter application comprises collecting 3D mapping data using the catheter, the 3D mapping
data comprising 3D coordinates of said series of different points on surfaces inside the heart contacted by the tip of the
catheter;

wherein ECG gating is used during said collecting of 3D mapping data to ensure that the 3D image data and the 3D mapping data
are recorded during a same heart phase;

wherein a plurality of magnetic fields are created outside of the patient, wherein an electromagnetic sensor in the catheter
detects said plurality of magnetic fields, and wherein a series of positions of the catheter are determined based on said
detection of magnetic fields by the electromagnetic sensor in the catheter;

(4) performing a registration process after the extraction step and while the catheter application is ongoing, the registration
process correlating the 3D surface profile created in the extraction step with 3D mapping data, the registration process comprising
a first stage and a later in time second stage;

said first stage of the registration process comprising matching anatomical point markers between the 3D surface profile and
the 3D mapping data;

wherein fluoroscope imaging is used for imaging the catheter and the heart during the first stage, and wherein fluoroscope
imaging is ended when said first stage of the registration process is completed;

said second stage of the registration process comprising surface matching between the 3D surface profile and the 3D mapping
data, the surface matching being point-to-surface matching between (i) 3D coordinates of said series of different points inside
the heart of the 3D mapping data, and (ii) the 3D surface profile;

wherein more 3D mapping data is available and used in the second stage of the registrations process than in the first stage,
with the second stage having greater accuracy than the first stage;

(5) displaying the 3D surface profile and 3D mapping data which has been correlated by the registration process;
wherein a position and orientation of the catheter is also displayed overlaid on said 3D surface profile and said 3D mapping
data; and

wherein the correlated 3D surface profile and 3D mapping data are linked during display such that rotation, movement, and
scaling of one is simultaneously applied to the other.

US Pat. No. 9,572,535

DYNAMIC MAPPING POINT FILTERING USING A PRE-ACQUIRED IMAGE

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:
acquiring, from an imaging system, an image of a body cavity;
receiving first and second sets of mapping points from a probe having a location sensor and inserted into the body cavity;
performing, by a processor, a first registration between the mapping points in the first set and the image, each of the mapping
points in the first set having a respective first point error value, the first registration having a first cumulative error
value indicating a quality of the first registration;

generating, using the first registration, a three-dimensional (3D) anatomical map comprising the mapping points in the first
set whose respective first point error values are less than a point error threshold;

performing a second registration between the mapping points in the first and the second sets and the image, each of the mapping
points in the first and the second sets having a respective second point error value, the second registration having a second
cumulative error value lower than the first cumulative error value; and

generating an updated 3D anatomical map comprising the mapping points in the first and the second sets whose respective second
point error values are less than the point error threshold.

US Pat. No. 10,211,559

PREVENTING UNWANTED CONTACT BETWEEN TERMINALS

BIOSENSE WEBSTER (ISRAEL)...

1. An electrical connector, comprising:a male-connector body comprising,
an expandable mating surface,
a hollow core defining a longitudinal axis, the hollow core having a first shape with a first minimum width perpendicular to the longitudinal axis, and
a plurality of electrically-conductive male-connector terminals coupled to the expandable mating surface; and
an insert having a second shape complementary to the first shape, the second shape having a second minimum width perpendicular to the longitudinal axis and greater than the first minimum width, such that upon disposition of the insert in the hollow core, the male-connector terminals move radially outward.

US Pat. No. 9,775,578

UNMAPPED REGION VISUALIZATION

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:
capturing a three dimensional image of at least part of a body cavity;
constructing a simulated surface of at least part of said body cavity using said three dimensional image, and showing the
simulated surface on a display;

after constructing said simulated surface, inserting a probe having a location sensor into said body cavity;
with the probe inserted inside said body cavity, mapping at least a portion of said body cavity corresponding to said simulated
surface, the mapping process comprising:

1. moving a tip of the probe to a position in the body cavity where the tip is positioned against a body cavity tissue, and
determining that the tip is positioned against the body cavity tissue;

2. determining a position of the tip of the probe while it is against the body cavity tissue using the location sensor in
the probe;

3. mapping said position of the tip of the probe while it is against the body cavity tissue with respect to the simulated
surface, and visually marking said position of the tip of the probe as a mapped region of the simulated surface on the display
by overlaying one of a plurality of different mapped visual designs on a corresponding area of the simulated surface,

3a. wherein mapped regions remain marked with one of said plurality of mapped visual designs at least until completion of
the mapping process;

3b. wherein areas of the simulated surface which remain unmapped are visually indicated as unmapped by overlaying a first
visual design on corresponding areas of the simulated surface unless and until the unmapped areas are mapped; and

3c. wherein said mapping and visual marking takes place without intervention from an operator;
4. moving the tip of the probe to a different position in the body cavity where the tip is positioned against body cavity
tissue; and

5. repeating steps 1-4 a plurality of times;
wherein at least some regions of the simulated surface which have been visually marked as being mapped on the display during
said mapping process are further modified during the course of the mapping process to visually indicate changing mapping resolution;

wherein mapping resolution corresponds to a number of different positions in a region of the simulated surface which have
been mapped by the mapping process;

wherein said plurality of mapped visual designs comprise a plurality of visually distinguishable mapping patterns each corresponding
to different respective mapping resolutions; and

wherein the display is modified during the course of the mapping process to reflect changes in mapping resolution in regions
of the simulated surface as additional tip positions are mapped;

the method further comprising presenting a legend on the display, the legend comprising the first visual design and the plurality
of mapped visual designs, the plurality of mapped visual designs comprising a range of mapping patterns corresponding to different
mapping resolutions.

US Pat. No. 9,833,161

BASKET CATHETER WITH FAR-FIELD ELECTRODE

Biosense Webster (Israel)...

1. A method, comprising the steps of:
inserting a catheter into a heart of a subject, the catheter having an elongated catheter body, the catheter body having an
interior, proximal end, a distal end and at least one lumen therethrough and having a basket-shaped assembly at the distal
end of the catheter body, the basket-shaped assembly having a longitudinal axis, a proximal extremity and a distal extremity
and comprising a plurality of splines connected at the proximal extremity and the distal extremity, the splines comprising
a plurality of spline electrodes, the basket-shaped assembly configurable in an expanded arrangement wherein the splines bow
radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis
of the catheter body, the catheter having a far-field electrode disposed in the interior of the expanded basket-shaped assembly;

expanding the basket-shaped assembly to contact at least one of the spline electrodes with a surface of the heart;
thereafter receiving an intracardiac electrogram with the at least one of the spline electrodes and receiving a far-field
electrogram with the far-field electrode, the intracardiac electrogram having a near-field component and a far-field component;

removing the far-field component from the intracardiac electrogram while retaining the near-field component by applying the
far-field electrogram to the intracardiac electrogram to generate a modified intracardiac electrogram; and

reporting the modified intracardiac electrogram.

US Pat. No. 9,638,820

CALIBRATION JIG FOR A FLAT LOCATION PAD

Biosense Webster (ISRAEL)...

1. An apparatus, comprising:
a detector assembly, comprising an array of multiple magnetic field detectors;
a positioning unit, which is configured to fix the detector assembly at one or more known positions relative to a location
pad, which generates magnetic fields for performing position measurements on an intra-body magnetic field detector using a
positioning system; and

interface circuitry, which is configured to output electrical signals that are produced by the magnetic field detectors of
the detector assembly when the detector assembly is fixed at the known positions, so as to calibrate the position measurements
performed by the positioning system;

wherein the positioning unit comprises at least one of:
multiple slots, which are configured to accept the detector assembly so as to fix the detector assembly at the respective
known positions relative to the location pad; or

an adapter conforming to a shape of the location pad; or
one or more turn screws, which are configured to be rotated so as to set the known positions of the detector assembly relative
to the location pad.

US Pat. No. 9,554,847

REAL TIME ASSESSMENT OF ABLATION FROM ELECTROCARDIOGRAM SIGNALS

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus, comprising:
an intra-body probe comprising an electrode, which is configured to contact tissue in a heart, wherein the electrode is configured
to receive ECG signals and apply a radio frequency ablation signal; and

a processor, which is configured to receive an electrical signal from the electrode, the electrical signal comprising a local
component and a remote-field contribution, to distinguish the local component, due to the tissue with which the electrode
is in contact, in the electrical signal from the remote-field contribution to the signal, and to control a therapeutic procedure
applied to the tissue responsively to the distinguished local component.

US Pat. No. 9,662,169

CATHETER WITH FLOW BALANCING VALVE

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated body;
a distal section having at least a first electrode and a second electrode, each electrode adapted for irrigation;
a control handle proximal the elongated body;
a coaxial irrigation tubing having at least an inner lumen and an outer lumen, the inner lumen dedicated to transporting fluid
to the first electrode, and the outer lumen dedicated to transporting fluid to the second electrode; and

a common valve comprising a moveable member, an inlet opening and an outlet opening, the outlet opening being fluidly connected
to both the inner lumen and the outer lumen of the coaxial irrigation tubing, the common valve having first and second separate
fluid flow pathways between the inlet opening and the outlet opening, the second fluid flow pathway extending around an exterior
surface of the moveable member and into the outer lumen, the first fluid pathway extending through the moveable member and
in the inner lumen, and the moveable member being configured to automatically move in response to a threshold fluid force
to thereby enlarge or expand the second fluid flow pathway.

US Pat. No. 10,004,417

METHOD FOR MAKING A LOW OHMIC PRESSURE-CONTACT ELECTRICAL CONNECTION BETWEEN SPLIT RING ELECTRODE AND LEAD WIRE

Biosense Webster (Israel)...

1. A method for attaching a split ring electrode to a tubing of a catheter, comprising:providing a tubing with at least one lumen, a side wall and at least one opening in the side wall providing communication between the at least one lumen and outside the tubing;
passing an electrode lead wire through the at least one lumen and out of the at least one opening to expose a distal portion of the electrode lead wire;
positioning the distal portion of the electrode lead wire on an outer surface of the tubing;
dispensing an electrically conductive adhesive on the outer surface of the tubing from a dispenser housing the electrically conductive adhesive by rotating the tubing underneath the dispenser while the dispenser dispenses the electrically conductive adhesive; and
mounting a split ring electrode on the outer surface of the tubing covering the opening, the distal portion of the electrode lead wire and the electrically conductive adhesive; and
heating the electrically-conductive adhesive to reflow.

US Pat. No. 9,724,154

IRRIGATED ABLATION CATHETER WITH MULTIPLE SENSORS

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter, comprising:
an elongated body;
an electrode mounted at a distal end of the elongated body, wherein the electrode is configured as a shell defining an interior
space;

a plurality of irrigation apertures formed in the shell and communicating with the interior space;
an insert disposed within the interior space having a plurality of protrusions configured to mate with a corresponding plurality
of orifices in the shell of the electrode, wherein each protrusion extends at least flush with an exterior surface of the
electrode and has a port communicating with at least one interior lumen in the insert;

a plurality of sensors, wherein each sensor is disposed within one of the ports of the protrusions; and
a support which forms a flight tight seal with a proximal-most end of the electrode and engages a proximal end of the insert
to stabilize the insert against rotational motion.

US Pat. No. 9,662,033

SYSTEM AND METHOD FOR VISUALIZING ELECTROPHYSIOLOGY DATA

Biosense Webster (Israel)...

1. A method for visualization of electrophysiology information sensed by electrodes on a catheter, comprising:
recording times of electrode signal acquisitions;
identifying the electrodes with signal acquisition;
designating a reference electrode signal acquisition;
assigning a relative time to each recorded time of electrode signal acquisition relative to the reference electrode signal
acquisition;

correlating assigned relative times to identified electrodes to generate a sequence of electrode signal acquisitions; and
generating a visual representation on a display with a plurality of separate images shown in series to represent a progression
of the sequence of electrode signal acquisitions, each of the plurality of separate images including a graphical image of
the electrodes, wherein individual electrodes are visually marked to represent the sequence of electrode signal acquisitions.

US Pat. No. 9,510,894

IRRIGATED ABLATION CATHETER HAVING IRRIGATION PORTS WITH REDUCED HYDRAULIC RESISTANCE

BIOSENSE WEBSTER (ISRAEL)...

1. An irrigated ablation catheter, comprising:
an elongated catheter body;
a deflectable section distal to the catheter body;
a tip electrode distal to the deflectable section, the tip electrode comprising:
an outer shell defining a cavity, the shell having a predetermined plurality of fluid ports, each fluid port contributing
to a total fluid output area of the tip electrode;

an internal member including a fluid inlet into the tip electrode, the fluid inlet having a fluid input area;
wherein each fluid port is tapered, and has a fluid port aspect ratio of a thickness of the outer shell to a diameter of the
fluid port of less than 3.25.

US Pat. No. 9,504,522

ELECTROCARDIOGRAM NOISE REDUCTION

Biosense Webster (Israel)...

1. A catheterization system, comprising:
a flexible catheter adapted for insertion into a heart of a living subject, having a distal portion and a lumen for passing
an electrolyte-containing fluid therethrough to exit the catheter at the distal portion, the lumen connectable to an irrigation
pump to form a fluid communication therewith;

a fluid reservoir connected to the irrigation pump for supplying the electrolyte-containing fluid to the catheter;
electrocardiogram circuitry connectable to the subject for monitoring electrical activity in the heart, the electrocardiogram
circuitry having an input; and

an electrically conductive cable linking the electrolyte-containing fluid with the input of the electrocardiogram circuitry
through an isolated ground.

US Pat. No. 9,980,652

MAPPING FORCE AND TEMPERATURE FOR A CATHETER

BIOSENSE WEBSTER (ISRAEL)...

1. Apparatus for displaying information, comprising:a probe comprising a proximal end and a distal end, the distal end of the probe configured to be inserted into a body of a subject and comprising:
a force sensor arranged at the distal end of the probe, the force sensor configured to sense a force signal indicative of a force exerted by the distal end of the probe on tissue of the subject, the force signal comprising a first indication of a magnitude of the force and a second indication of a force-direction of the force; and
temperature sensors arranged at the distal end of the probe, the temperature sensors configured to sense temperature signals of temperatures in a vicinity of the distal end of the probe;
a display screen; and
a processor configured to receive the force signal and the temperature signals, to display on the display screen in a single map a graphical representation showing a distribution of the temperatures with a vector representation of the force superimposed on the distribution of the temperatures;
wherein the vector representation comprises the first indication of a magnitude of the force and the second indication of a force-direction of the force.

US Pat. No. 9,970,813

UV DETECTION OF STERILANT CONCENTRATION AND DISSIPATION IN A VOLUME OF A CHAMBER

Biosense Webster (Israel)...

1. A method for UV detection of sterilant concentration and dissipation in a volume, comprising:focusing cameras on at least one point of an object in the volume;
transmitting UV light and sterilant into the volume;
scanning, using the cameras, the at least one point of the object and determining an amount of absorbance at the at least one point;
calculating, from said determined amount of absorbance, a concentration of the sterilant for each of the at least one point; and, when the concentration is greater than a threshold, removing the sterilant from the volume.

US Pat. No. 9,848,799

REAL-TIME GENERATION OF MRI SLICES

Biosense Webster (ISRAEL)...

1. A method, comprising:
displaying a position of a distal end of a medical probe that is being navigated in an organ of a patient on a three-dimensional
(3D) map of the organ; and

in response to an event, selecting a plane of interest comprising the distal end, acquiring a real-time Magnetic Resonance
Imaging (MRI) slice of the organ at the selected plane, and displaying the MRI slice overlaid on the 3D map;

wherein the 3D map of the organ is created by a 3D magnetic position tracking system.

US Pat. No. 9,788,895

BASKET CATHETER WITH DEFLECTABLE SPINE

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
an electrode assembly at the distal end of the catheter body, the electrode assembly having proximal and distal ends and comprising
a plurality of spines, the spines comprising a plurality of electrodes;

an expander having proximal and distal ends, the expander forming a longitudinal axis of the assembly, the spines attached
at their proximal ends to the catheter body and at their distal ends to the expander;

at least one puller wire that extends through the expander, the puller wire having a distal end anchored in the expander at
a location distal of the distal end of the catheter body and proximal of the distal end of the assembly;

at least one proximal location sensor and at least one distal location sensor; and
a control handle proximal of the catheter body, the control handle having an actuator adapted to move the at least one puller
wire,

wherein the electrode assembly has an expanded arrangement when the expander is moved proximally along the longitudinal axis
relative to the catheter body and the electrode assembly has a collapsed arrangement when the expander is moved distally along
the longitudinal axis relative to the catheter body, and

wherein the expander is adapted to deflect in at least one direction when the at least one puller wire is moved by the actuator.

US Pat. No. 9,743,991

REAL-TIME ESTIMATION OF TISSUE PERFORATION RISK DURING MINIMALLY INVASIVE MEDICAL PROCEDURE

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus for performing a medical procedure, comprising:
an invasive probe comprising a probe tip, which is configured to be coupled to tissue in an organ of a patient; and
an electrode proximal to a distal end of the invasive probe;
a magnetic field sensor within the distal end of the invasive probe, the magnetic field sensor configured to generate electrical
position signals; and

a processor, which is coupled to the invasive probe and is configured to
measure a mechanical force exerted by the probe tip on the tissue and a displacement of the probe tip created by the mechanical
force,

to calculate a dependence of the mechanical force on the displacement, and
to estimate, based on the calculated dependence, a risk level of perforation of the tissue due to the mechanical force of
the probe tip on the tissue,

wherein the electrode is configured to measure local electrical potential at a plurality of locations in the organ of the
patient to obtain a plurality of local electrical potential measurements,

wherein the processor is configured to correlate the local electrical potential measurements, derived from the electrical
position signals of the magnetic field sensor, with the local electrical potential measurements to determine a plurality of
map points,

wherein each of the map points comprises a coordinate on an inner surface of the organ and a respective local electrical potential
measurement at the coordinate,

wherein the processor is configured to employ the coordinates of the map points to construct a simulation of the inner surface
of the organ, and

wherein the processor is configured to combine the local electrical potential measurements of the map points with the simulation
of the inner surface of the organ to produce a map of electrical potentials overlaid on the simulation of the inner surface
of the organ,

wherein the processor is configured to perform the steps of:
setting a measurement index,
receiving a first force measurement and first displacement measurement pair, incrementing the measurement index and
saving the first force measurement and first displacement measurement in a memory,
upon receiving a second force measurement and second displacement measurement pair, calculating an instantaneous gradient
value (Si), based on the change in force (AFi) and a change in displacement (ADi), and saving the instantaneous gradient value
(Si) in the memory, wherein when either the change in force (AFi) or the change in displacement, (ADi) are below a predefined
threshold, a previously-calculated instantaneous gradient value (Si) is saved in the memory, and

checking the instantaneous gradient value (Si), wherein when the instantaneous gradient value (Si) is negative, issuing an
alert that perforation has occurred and when the instantaneous gradient value (Si) is not negative, proceeding to a slope
comparison step, the slope comparison step comprising the step of determining whether the instantaneous gradient value (Si)
is greater than a gradient value threshold (TH), wherein when the instantaneous gradient value (Si) is greater than a gradient
value threshold (TH), the processor issues an alert indicating a perforation risk,

wherein the processor automatically issues instructions to reduce a supply of RF energy to the invasive probe when the instantaneous
gradient value (Si) is negative, and

wherein the processor automatically issues instructions to reduce the supply of RF energy to the invasive probe when the instantaneous
gradient value (Si) is greater than a gradient value threshold (TH).

US Pat. No. 9,713,435

CARDIAC MAPPING USING NON-GATED MRI

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus, comprising:
a Magnetic Resonance Imaging (MRI) scanner, which is configured to acquire a plurality of non-gated MRI data points of a cardiac
chamber, acquired over multiple phases of at least one cardiac cycle;

an intra-cardiac probe comprising a position sensor configured to generate position signals used to determine position coordinates
of a distal end of the intra-cardiac probe, the intra-cardiac probe configured to acquire parameter measurements of a parameter
acquired at respective points on a surface of the cardiac chamber;

a display;
a control console which performs the steps of:
receiving the position signals from the position sensor,
determining position coordinates of the distal end of the intra-cardiac probe based on the position signals,
receiving the parameter measurements of the parameter acquired at respective points on the surface of the cardiac chamber
by the intra-cardiac probe,

collecting the non-gated MRI data points of the cardiac chamber from the MRI scanner, and
transmitting the non-gated MRI data points; and
a processor operatively connected to the control console, the processor comprising a computer having tangible non-transitory
computer-readable medium, in which program instructions are stored, which instructions, when read by the computer, cause the
computer to:

(1) accept the non-gated MRI data points transmitted by the MRI module,
(2) identify a volume of the cardiac chamber containing the accepted non-gated MRI data points,
(3) construct a simulated surface of the volume and display on the display the simulated surface comprising a wall of the
cardiac chamber,

(4) accept from the control console parameter measurements of a parameter acquired at respective points on the surface of
the cardiac chamber by the intra-cardiac probe and position coordinates obtained by magnetic position sensors, where the position
coordinates correspond to the parameters, and associating each parameter measurement with a respective point on the simulated
surface based on the position coordinates of each respective point,

(5) producing an electrical map of electrical potential measurements of the surface of the cardiac chamber by overlaying the
associated parameter measurements on the simulated surface of the volume,

(6) update the simulated surface on the cardiac chamber in real time based on the acquired MRI data points and displaying
on the display.

US Pat. No. 9,700,373

SEGMENTED BALLOON CATHETER

BIOSENSE WEBSTER (ISRAEL)...

1. A method of catheterization, comprising the steps of:
introducing into a heart chamber of a subject a catheter having an elongated shaft and a distal portion, the distal portion
comprising an inflatable assembly, the heart chamber having walls, wherein the inflatable assembly comprises:

a containment chamber having an outer wall, an outer surface, an axial core and a plurality of longitudinally oriented partitions
extending from the axial core to the outer wall to divide the containment chamber into at least four inflatable sectors, the
sectors being externally delimited by respective bounding portions of the outer surface, the outer surface having perforations
formed therethrough, the sectors being arranged such that pairs of the sectors oppose one another across the axial core;

hydraulic valves connected to respective sectors to enable selective inflation of diametrically opposed sectors by a fluid
when the valves are connected to a source of the fluid;

at least one surface electrode mounted on each of the bounding portions, the at least one surface electrode being deformable,
the at least one surface electrode being adapted to receive an electric current and ablate a portion of a heart chamber wall;
and

a tip electrode disposed on the catheter distal to the inflatable assembly, the tip electrode adapted to provide measurements
and further adapted to ablate a portion of a heart chamber wall, and

a control processor operative to control the valves to admit the fluid into a selected pair of diametrically opposed sectors
and to exclude the fluid from sectors other than the selected pair of diametrically opposed sectors, the control processor
adapted to cool at least one surface electrode of the selected pair of diametrically opposed sectors by egress of the fluid
from the containment chamber via the perforations,

wherein the assembly is adapted to provide verification of electrical contact between the heart chamber wall and electrodes
of diametrically opposed sectors;

and inflating a selected one of the pairs of diametrically opposed sectors sufficiently to stably press the outer surface
of the pairs of the inflated diametrically opposed sectors against the walls of the heart chamber while avoiding inflation
of others of the sectors wherein the at least one surface electrode of each sector of the selected diametrically opposed pair
contacts the walls of the heart chamber.

US Pat. No. 9,696,131

ADAPTIVE FLUOROSCOPE LOCATION FOR THE APPLICATION OF FIELD COMPENSATION

Biosense Webster (ISRAEL)...

1. A method, comprising the steps of:
in a calibration phase performing the steps of:
generating a magnetic field in a region using a plurality of magnetic field generators;
placing a field-perturbing element in known positions within the region; and
creating a reaction field model by calculating respective reaction magnetic fields while the field-perturbing element is in
the known positions; and

in an operational phase performing the steps of:
placing the field-perturbing element in a new position within the region;
disposing a magnetic field location sensor between the field-perturbing element and the magnetic field generators;
introducing a distal segment of a probe into the region, a probe magnetic field sensor being disposed on the distal segment;
regenerating a perturbed magnetic field with the magnetic field generators;
obtaining first measurements of the perturbed magnetic field from the probe magnetic field sensor;
obtaining second measurements of the perturbed magnetic field from the location sensor;
reconstructing the new position of the field-perturbing element from the second measurements;
obtaining a predicted reaction magnetic field for the reconstructed new position from the reaction field model;
obtaining a compensated measurement by subtracting the predicted reaction magnetic field from the second measurements;
adjusting the first measurements according to the compensated measurement; and
calculating a position of the probe magnetic field sensor using the adjusted first measurements;
wherein obtaining a compensated measurement comprises:
defining a cost function based on a difference between the second measurements and the predicted reaction magnetic field;
minimizing the cost function by finding optimum values of parameters of the perturbed magnetic field obtained in the second
measurements; and

defining an optimized reaction field having the optimum values of the parameters; and
wherein the optimum values of parameters comprises fluoroscopic parameters representing three rotation angles; x- and y-offsets
of fluoroscope center of rotation; z-offset of detector, and z-offset of the collimator and six location sensor parameters
representing three rotation angles and x-, y- and z-offsets.

US Pat. No. 9,682,214

CONTROL HANDLE WITH ROTATIONAL CAM MECHANISM FOR CONTRACTION/DEFLECTION OF MEDICAL DEVICE

Biosense Webster (Israel)...

1. A medical device comprising:
an elongated body;
a deflectable section distal the elongated body;
a member distal the deflectable section, the member having a configuration;
a control handle proximal the elongated body, the control handle having a longitudinal axis;
a deflection assembly comprising a deflection arm rotatable about a deflection axis generally transverse to the longitudinal
axis of the control handle;

a control assembly comprising a rotational cam, a shaft, and a pulley, the rotational cam being in a circumferential relationship
with a portion of the control handle and adapted for rotation about the longitudinal axis, the rotational cam having an inner
surface with two opposing helical tracks, the portion of the control handle having two opposing linear guide slots extending
in parallel with the longitudinal axis, the shaft extending along a diameter of the portion of the control handle generally
perpendicular to the longitudinal axis, the shaft having two opposing ends, each of which extends through a respective guide
slot and is received in a respective helical track, the pulley being mounted on the shaft;

first and second puller members responsive to rotation of the deflection assembly such that rotation of the deflection arm
results in deflection of the deflectable section, and

a third puller member wrapped about the pulley,
wherein rotation of the rotational cam about the longitudinal axis by a user actuates movement of the shaft relative to the
control handle along the longitudinal axis, thereby acting on the third puller member via the pulley to change the configuration
of the member.

US Pat. No. 9,603,669

PRESSURE SENSING FOR A MULTI-ARM CATHETER

Biosense Webster (Israel)...

11. A medical apparatus comprising: a central shaft having a distal end; a plurality of arms each having a distal end that
extends outward from the central shaft with each arm having a position transducer coupled thereto, the arms configured to
press against an intra-body surface, so as to cause the arms to exert pressure on the surface and bend with respect to the
central shaft in response to the pressure; a processor configured to measure positions of the respective position transducers
coupled to the arms and estimate the pressure exerted by at least one arm on the intra-body surface by calculating at least
one angle between the central shaft and the at least one arm, and to estimate the pressure exerted by the at least one arm
on the intra-body surface responsively to the at least one angle.

US Pat. No. 9,526,866

CATHETER ENTANGLEMENT INDICATION

Biosense Webster (Israel)...

1. Apparatus, comprising:
an elongated probe having proximal and distal ends;
a sensor coupled to the elongated probe and configured to generate signals used for determining location and orientation coordinates
of the elongated probe;

a processor operatively connected to the sensor, the processor being configured to receive signals from the sensor indicative
of the location and orientation coordinates of the elongated probe and subsequently determine a cumulative angle of rotation
that is applied by an operator to the proximal end of the probe while the operator manipulates the proximal end so as to move
the distal end within a body of a patient based on the signals; and

an output device operatively connected to the processor, the output device being configured to present an indication of the
cumulative angle of rotation to the operator.

US Pat. No. 9,956,035

TEMPERATURE MEASUREMENT IN CATHETER

Biosense Webster (Israel)...

1. An apparatus, comprising:a probe having an ablation electrode and a plurality of microelectrodes, wherein the microelectrodes are distributed circumferentially in a radially spaced apart relation on an external surface of the probe, or in perforations in the external surface of the probe;
first electrical circuitry linked to the microelectrodes for determining impedances of the microelectrodes, wherein the first electrical circuitry is configured to operatively identify a pair of the microelectrodes having a highest and a second highest impedance for determining a bipolar impedance between the pair of the microelectrodes;
second electrical circuitry configured for determining a tissue temperature responsively to the bipolar impedance; and
a power generator linked to the ablation electrode.

US Pat. No. 9,788,894

CATHETER WITH DISTAL SECTION HAVING SIDE-BY-SIDE LOOPS

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body;
a distal section distal the catheter body and having a flexible elongated member with shape memory, the member being configured
to assume a 2D configuration comprising a first loop in a first direction and a second loop in a second direction opposite
the first direction, the 2D configuration terminating in a free distal end of the member; and

at least one electrode mounted on the member.

US Pat. No. 9,782,099

BASKET CATHETER WITH IMPROVED SPINE FLEXIBILITY

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
a basket-shaped electrode assembly at the distal end of the catheter body, the basket-shaped electrode assembly having proximal
and distal ends and comprising a plurality of spines, at least one spine having an equatorial region of greater flexibility
and proximal and distal regions of lesser flexibility, the basket-shaped electrode assembly being movable between a collapsed
configuration, an expanded configuration in which the spines bow radially outward relative to the catheter body to form a
first expanded shape, and a hyper-expanded configuration in which the spines bend at the equatorial region of greater flexibility
to thereby deform the first expanded shape, shorten a length of the basket-shaped electrode assembly and assume a V shape
with an acute bend in the equatorial region of greater flexibility.

US Pat. No. 9,717,554

CATHETER WITH COMPOSITE CONSTRUCTION

Biosense Webster (Israel)...

1. A catheter adapted to carry a position sensor, comprising:
an elongated catheter body;
a distal section distal the catheter body, the distal section having a longitudinal axis and a composite construction comprising:
a tip electrode;
an irrigation tubing extending along the longitudinal axis;
at least one deflectable member extending along a first segment of the longitudinal axis proximal of the tip electrode and
mounted in surrounding relation on the irrigation tubing;

at least one support member extending along a second segment of the longitudinal axis proximal of the tip electrode, the at
least one support member being separate from and less flexible than the at least one deflectable member, and the at least
one support member being mounted in surrounding relation on the irrigation tubing, and carrying a respective ring electrode
that is separate from the tip electrode;

the irrigation tubing defining a distal irrigation fluid path along the longitudinal axis through the at least one deflectable
member and the at least one support member to deliver irrigation fluid to the respective ring electrode and the tip electrode.

US Pat. No. 9,649,158

CATHETER FOR TREATMENT OF ATRIAL FLUTTER HAVING SINGLE ACTION DUAL DEFLECTION MECHANISM

Biosense Webster (Israel)...

1. A deflectable catheter comprising:
an elongated catheter body having an outer wall, proximal and distal ends, and at least one lumen extending therethrough;
a distal tip section comprising a flexible tubing having a proximal end and a distal end and a plurality of lumens extending
therethrough, the proximal end of the tip section being fixedly attached to the distal end of the catheter body, the distal
tip section further comprising a nitinol tube having slots formed therein; and

a puller wire extending through the elongated catheter body and distal tip section,
wherein the nitinol tube and the puller wire are configured such that a single longitudinal movement of the puller wire effects
both a proximal deflection in the elongated catheter body and a distal deflection in the distal tip section.

US Pat. No. 9,577,656

NARROWBAND ANALOG NOISE CANCELLATION

Biosense Webster (Israel)...

1. A method for cancelling noise in a medical system, the method comprising the steps of:
providing a medical system comprising (i) an analog-to-digital (A/D) converter which is coupled to receive an input analog
signal containing noise at a specific noise frequency, (ii) a signal analyzer, (iii) an analog signal generator which is configured
to generate an analog correction signal, and (iv) a summation block which sums the input analog signal with the analog correction
signal to generate an output analog signal;

receiving an input analog signal containing noise at a specific noise frequency at the analog-to-digital (A/D) converter;
digitizing the input analog signal with the analog-to-digital (A/D) converter to form a digitized signal;
recovering a first amplitude and a first phase of the noise from the digitized signal with the signal analyzer;
generating an analog correction signal at the specific noise frequency having a second amplitude equal to the first amplitude
and a second phase opposite to the first phase with the analog signal generator; and

summing the input analog signal with the analog correction signal with the summation block to generate an output analog signal.

US Pat. No. 9,510,786

OPTICAL PRESSURE MEASUREMENT

Biosense Webster (Israel)...

1. Sensing apparatus, comprising:
a tubular catheter probe having a tubing wall, a proximal end and a distal end terminating in a distal tip, the distal tip
being cylindrically shaped with an open distal end, and having an axis of symmetry,

a sensor mounted within the distal tip, the sensor comprising a transparent, solid medium having a proximal surface and an
elastic, distal outer surface, the elastic, distal outer surface being configured to contact a tissue within a living body
and to deform in response to a force exerted by the body tissue on the distal outer surface;

a radiation source contained within the tubing wall and coupled to the proximal surface of the transparent solid medium, the
radiation source being configured to direct radiation through the transparent solid medium toward the distal outer surface;

a radiation detector contained within the tubing wall and coupled to the proximal surface of the transparent solid medium,
the radiation detector being configured to sense the radiation that is reflected from the distal outer surface and to output
a signal indicative of an amplitude of the reflected radiation; and

a processor, which is operatively coupled to the radiation source and the radiation detector and configured to measure a change
in the signal due to deformation of the surface and, responsively to the change, to output an indication of the force.

US Pat. No. 10,039,494

BASKET CATHETER WITH MICROELECTRODE ARRAY DISTAL TIP

Biosense Webster (Israel)...

1. A catheter comprising:an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
a tip assembly at the distal end of the catheter body, the tip assembly comprising:
a substrate body having proximal and distal ends and a generally solid and unitary construction,
a plurality of recessed microelectrodes embedded in an outer surface of the substrate body so that the recessed microelectrodes are flush with the outer surface of the substrate body,
a plurality of microelectrode lead wires, each of the microelectrode lead wires corresponding to one of the plurality of recessed microelectrodes, and
at least first and second isolated through holes in the solid construction of the substrate body, at least one of the plurality of microelectrode lead wires extending from the respective microelectrode through the first isolated through hole to the proximal end of the substrate body, and at least one other of the plurality of microelectrode lead wires extending from its respective microelectrode through the second isolated through hole to the proximal end of the substrate body.

US Pat. No. 9,974,608

DETERMINING ABSENCE OF CONTACT FOR A CATHETER

Biosense Webster (Israel)...

1. A method for measuring force while compensating for drift, comprising:injecting a current between an electrode of a catheter and tissue in proximity to the catheter, the catheter comprising a force sensor configured to measure a force between the catheter and the tissue;
measuring in succession, a plurality of phase shifts of the current relative to a fixed reference;
populating one or more bins of a histogram of the phase shifts;
determining a condition for zeroing by verifying that a cardinality of the measured phase shifts in a particular bin falling below a predetermined threshold increases over a predetermined time period; and
compensating for drift during the condition for zeroing by calibrating a zero-force point for the force sensor according to the force measured by the force sensor during the predetermined time period.

US Pat. No. 9,833,165

CHECKING FOR PERFORATION OF THE EPICARDIUM USING MAGNETIC RESONANCE IMAGING

Biosense Webster (ISRAEL)...

1. A computer implemented method for a medical apparatus comprising a probe adapted for insertion into a heart having a pericardium
thereabout, the pericardium having a visceral layer and a parietal layer, a memory having the computer implemented method
stored therein, a display and a processor linked to the display and a MRI apparatus and being coupled to access the memory
to execute the computer implemented method, the computer implemented method comprising the steps of:
acquiring a first set of magnetic resonance imaging (MRI) data from the MRI apparatus that includes the pericardium and subsequently
acquiring a second set of MRI data from the MRI apparatus that includes the pericardium;

measuring the pericardium by analyzing the first and second sets of MRI;
making a determination that a measurement of the pericardium in the second set of MRI data differs from the measurement of
the pericardium in the first set of MRI data; and

responsively to the determination reporting a change in configuration of the pericardium,
wherein the steps of acquiring, measuring, making a determination, and reporting are performed while a medical procedure is
being performed;

wherein measuring comprises detecting a separation of the visceral layer from the parietal layer of the pericardium and making
a determination comprises detecting a change in a distance between the visceral layer and the parietal layer that exceeds
a predetermined value.

US Pat. No. 9,820,664

CATHETER WITH HIGH DENSITY ELECTRODE SPINE ARRAY

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body; and
a distal electrode assembly, the distal electrode assembly comprising at least three spines extending in a common plane, each
spine having at least one electrode, a proximal spine portion, a distal spine portion, and a free distal end,

wherein the catheter body defines a longitudinal axis, and each proximal spine portion is configured to extend at an angle
from the longitudinal axis of the catheter body and each distal spine portion is configured to extend generally parallel to
the longitudinal axis of the catheter body and generally parallel to each other distal spine Portion.

US Pat. No. 9,737,353

SYSTEM FOR CONTROLLING TISSUE ABLATION USING TEMPERATURE SENSORS

Biosense Webster (Israel)...

1. A method of body tissue ablation, comprising the steps of:
inserting a probe into a body of a living subject;
urging the probe into contact with a tissue in the body;
generating ablative energy at a power output level at a level of current;
transmitting the generated energy into the tissue via the probe;
determining a measured temperature of the tissue and a measured power level of the generated energy during the step of transmitting
the generated energy into tissue via the probe, via a temperature sensor and a power sensor;

determining a power deviation by comparing a difference between the measured power level and a predetermined target power
level;

determining a temperature deviation by comparing a difference between the measured temperature of the tissue and a predetermined
target temperature;

calculating a target current value from a control function; and
via a controller, controlling the power output level responsively to the calculated target current value by incrementally
adjusting the level of current to the target current value gradually over time to generate energy at a new power output level
until the measured temperature of the tissue and the measured power level each reach the predetermined target power level
and the predetermined target temperature respectively, wherein the control function is:

or
wherein:
Ii+1 is the target current value;

Ii is the target current value of a previous iteration;

Pmeas is the measured power level;

Ptarg is the target power level;

Tmeas is the measured temperature;

Ttarg is the target temperature;

k is a damping constant; and
C is a constant having a value of ?1 if both Pmeas is greater than Ptarg and Tmeas is greater than Ttarg, and +1 otherwise.

US Pat. No. 9,754,372

MARKING OF FLUOROSCOPE FIELD-OF-VIEW

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising;
registering a first coordinate system of a fluoroscopic imaging system and a second coordinate system of a magnetic position
tracking system;

displaying a three-dimensional (3D) magnetic position tracking map of an organ of a patient, which is produced by the magnetic
position tracking system;

calculating, based on aligned coordinates of the registered first and second coordinate systems, a 3D volume that would be
irradiated by the fluoroscopic imaging system according to a direction in which the fluoroscopic imaging system is pointing;
and

marking the calculated 3D volume on the 3D magnetic position tracking map.

US Pat. No. 9,721,379

REAL-TIME SIMULATION OF FLUOROSCOPIC IMAGES

Biosense Webster (Israel)...

1. A method, comprising:
registering a first coordinate system of a fluoroscopic imaging system and a second coordinate system of a magnetic position
tracking system;

computing a three-dimensional (3D) map of an organ of a patient using the magnetic position tracking system;
using the registered first and second coordinate systems, calculating a field-of-view (FOV) of the fluoroscopic imaging system
in the second coordinate system;

creating from the 3D map a two-dimensional (2D) image that simulates a fluoroscopic image that would be generated by the fluoroscopic
imaging system if radiation was applied to a subject by the fluoroscopic imaging system at the calculated FOV; and

displaying the 2D image that simulates the fluoroscopic image.

US Pat. No. 9,642,674

METHOD FOR MAPPING VENTRICULAR/ATRIAL PREMATURE BEATS DURING SINUS RHYTHM

BIOSENSE WEBSTER (ISRAEL)...

1. A medical apparatus, comprising:
a probe, adapted for insertion into a heart, the probe comprising an elongated body, and a mapping electrode disposed on a
distal portion of the body;

a memory having programs stored therein;
a display; and
a processor linked to the display and being coupled to access the memory to execute the programs, the processor being connectable
to receive an input provided by the mapping electrode, wherein the programs cause the processor to perform the steps of:

obtaining electrocardiographic signals from a target in the heart via the mapping electrode;
holding a series of the electrocardiographic signals in a beat buffer;
freezing the beat buffer to prevent replacement by new beats;
identifying a beat in the beat buffer indicating a PVC (premature ventricular contraction), said beat being a PVC beat,
acquiring a PVC point based on the PVC beat, said PVC point only being acquired if the cycle length of the PVC beat falls
within a predetermined range;

identifying an SR (sinus rhythm) beat from the beat buffer, said SR beat representing normal sinus rhythm;
acquiring an SR point based on said SR beat;
displaying the PVC point and the SR point on a single electroanatomic map;
associating the local activation time (LAT) of the PVC point with the SR point in a single representative display, said association
being accomplished by assigning the LAT of the PVC to the SR point; and

generating a further electroanatomic map, said further electroanatomic map being an SR-PVC map, said SP-PVC map reflecting
the assignment of the LAT of the PVC to the SR point, said SR-PVC map reflecting a geometry of the heart during sinus rhythm,
while reflecting activation time of the heart while experiencing PVC,

whereby ablation may be performed at data-adjusted SR points with an ablation catheter displayed in SR locations, wherein
navigation of an ablation electrode may be guided by the SR-PVC map.

US Pat. No. 9,672,607

IDENTIFICATION AND REGISTRATION OF MULTI-MARKER JIG

Biosense Webster (Israel)...

1. A method for registering coordinate systems, comprising the steps of:
positioning a calibration jig having markers that are opaque to an imaging modality in an imaged area, wherein the markers
comprise at least two collinear marker quadruples having respective marker cross ratios;

producing with the imaging modality an image of the markers;
detecting the markers on the image;
on the image identifying collinear image quadruples of the detected markers;
computing respective image cross ratios of the collinear image quadruples;
defining candidate lines by associating at least one collinear marker quadruple and at least one collinear image quadruple
that have matching marker cross ratios and image cross ratios according to predefined criteria;

performing respective registrations of the calibration jig with the image using pairs of the candidate lines;
determining residuals of the registrations; and
selecting one of the registrations wherein the pair of the candidate lines thereof is associated with a qualifying residual
that is smaller than a predetermined value.

US Pat. No. 9,554,718

DOUBLE BIPOLAR CONFIGURATION FOR ATRIAL FIBRILLATION ANNOTATION

Biosense Webster (Israel)...

1. A method, comprising the steps of:
inserting a probe into a heart of a living subject, the probe having a plurality of unipolar electrodes;
for a plurality of pairs of unipolar electrodes, recording a bipolar electrogram from electrical signals received from a pair
of unipolar electrodes at a location in the heart and a unipolar electrogram from one of the electrodes of the pair of electrodes;

defining a time interval comprising a window of interest wherein a rate of change in a potential of the bipolar electrogram
exceeds a predetermined value;

establishing an annotation in the unipolar electrogram, wherein the annotation denotes a maximum rate of change in a potential
of the unipolar electrogram within the window of interest;

assigning a quality value to the annotation; and
generating a 3-dimensional map of a portion of the heart wherein the map includes the annotation and the quality value thereof.

US Pat. No. 10,004,416

CATHETER HAVING CLOSED LOOP ARRAY WITH IN-PLANE LINEAR ELECTRODE PORTION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:an elongated catheter body having a distal end; and
a distal electrode array mounted on the distal end of the catheter body, the distal electrode array comprising a plurality of offset spine loops, each spine loop having at least a pair of electrode-carrying portions and a distal portion connecting the pair of electrode-carrying portions, wherein the electrode-carrying portions of the plurality of offset spine loops lie in a single common plane, and the distal portions of the plurality of offset spine loops are angled out of the single common plane.

US Pat. No. 9,993,285

SYSTEM FOR CONTROLLING TISSUE ABLATION USING TEMPERATURE SENSORS

Biosense Webster (Israel)...

1. A method of body tissue ablation, comprising:inserting a probe into a body of a living subject;
urging the probe into contact with a tissue in the body;
generating ablative energy at a power output level at a level of current;
transmitting the generated ablative energy into the tissue via the probe;
determining a measured temperature of the tissue and a measured power level of the generated ablative energy during the transmitting of the generated ablative energy into the tissue;
determining a power deviation by comparing a difference between the measured power level and a predetermined target power level;
determining a temperature deviation by comparing a difference between the measured temperature of the tissue and a predetermined target temperature;
calculating a target current value from a control function, wherein the control function is:

in which:
Inew is the target current value;
Ipresent is the target current value in a previous iteration;
Pmeas is the measured power level;
Ptarg is the target power level;
Tmeas is the measured temperature;
Ttarg is the target temperature;
k is a damping constant; and
C is a constant having a value of ?1 if both Pmeas is greater than Ptarg and Tmeas is greater than Ttarg, and +1 otherwise; and
controlling the power output level responsively to the calculated target current value by incrementally adjusting the level of current to the target current value gradually over time to generate the ablative energy at a new power output level until the measured temperature of the tissue reaches the predetermined target temperature and the measured power level reaches the predetermined target power level, the controlling the power output level further comprising restricting or terminating the generation of the ablative energy when a predetermined ablation condition is met.

US Pat. No. 9,949,656

CATHETER WITH STACKED SPINE ELECTRODE ASSEMBLY

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:an elongated catheter body;
an electrode array distal of the catheter body, the array comprising:
at least first and second spine supports, each spine support including a base having a planar configuration, and a plurality of spines extending from the base; and
one or more electrodes carried on the spines,
wherein the first base extends in a first plane and the second base extends in a second plane different from the first plane.

US Pat. No. 9,717,559

CATHETER WITH ADJUSTABLE ARCUATE DISTAL SECTION

BIOSENSE WEBSTER (ISRAEL)...

8. A catheter comprising:
an elongated body having a longitudinal axis;
a distal assembly distal the elongated body, the distal assembly having a hollow support member defining a first predetermined
form having a first curvature;

at least one electrode mounted on the distal assembly;
a control handle proximal the elongated body;
a contraction wire extending through the elongated body and the distal assembly, wherein longitudinal movement of the contraction
wire results in contraction of the first predetermined form; and

a mandrel defining a second predetermined form having a second curvature that is different from the first curvature of the
first predetermined form, the mandrel being adapted for insertion into the hollow support member.

US Pat. No. 9,681,818

DETECTION AND DISPLAY OF IRREGULAR PERIODIC WAVEFORMS

BIOSENSE WEBSTER (ISRAEL)...

1. A method for diagnosing atrial fibrillation in a subject, comprising:
acquiring an electrocardiogram (ECG) signal from a heart of the subject over multiple heart cycles;
partitioning the ECG signal into a succession of synchronized segments each having respective start times at a selected annotation
point in the respective heart cycles, wherein said synchronized segments each represent heart cycles occurring at different
time points;

providing a display screen having a display axis, the display axis representing a time period corresponding to one synchronized
segment;

simultaneously displaying graphical representations of a plurality of synchronized segments on the display axis, such that
synchronized segments corresponding to ECG signals from a plurality of different heart cycles occurring at different time
points are simultaneously overlaid on the display axis, and wherein said graphical representations of the plurality of synchronized
segments at least partially overlap on the display screen;

wherein additional synchronized segments are continuously created as the ECG signal is received from the heart of the subject,
wherein graphical representations of newly created synchronized signals are continuously added to the display axis on the
display screen, and wherein graphical representations of older synchronized signals are removed from the display axis after
a period of time;

wherein each synchronized segment is first presented on the display screen with an initial display intensity at a respective
display time corresponding to a respective start time of the synchronized segment;

gradually decreasing a display intensity of the graphical representation of each synchronized segment overlaid on the display
screen as a decaying function of a time elapsed since the respective display time until each synchronized segment is, in respective
turn, removed from the display axis; and

wherein graphical representations of synchronized segments having a plurality of different respective display intensities
are simultaneously presented on the display axis;

the method further comprising:
determining whether said plurality of graphical representations of the plurality of synchronized segments on the display axis
comprise both (i) one or more synchronized segments which each include an irregular but periodic wave form, and also (ii)
one or more synchronized segments which do not include said irregular but periodic wave form; and

diagnosing atrial fibrillation in the subject when condition (i) and (ii) are both satisfied.

US Pat. No. 9,640,198

CONTROLLING A SYSTEM USING VOICELESS ALARYNGEAL SPEECH

Biosense Webster (Israel)...

6. A method for eliminating muffled speech caused by a physician's mask used by an operator conducting a medical procedure,
comprising the steps of:
providing a probe configured to be inserted into a patient's body by the operator, the probe being configured to be used by
the operator for performing the medical procedure in the patient's body;

fixing a sensor to a neck of an operator of equipment, the sensor being configured for sensing a voiceless alaryngeal speech
vibration generated by the operator during operation of the equipment;

displaying one or more graphic user interfaces on a screen while the probe is being used by the operator in the patient's
body and providing feedback to the operator during the medical procedure;

receiving and processing a signal output by the sensor during mouthing of muffled speech through the physician mask by the
operator so as to measure the voiceless alaryngeal speech vibration and so as to generate a control signal indicative of a
particular action to be taken by the equipment using the probe responsively to the measured voiceless alaryngeal speech vibration
during the medical procedure; and

verifying the particular action to be taken with the probe in the patient's body by displaying a query on the screen for the
operator to confirm using the one or more graphic user interfaces.

US Pat. No. 9,625,993

TOUCH FREE OPERATION OF DEVICES BY USE OF DEPTH SENSORS

Biosense Webster (Israel)...

1. A system for touch free operation of a medical 3D mapping system comprising:
a depth sensor for detecting body motion movements;
a motion software module operable to receive the detected body motion movements from the depth sensor, the software module
being configured to:

track a series of body motion movements,
deduce a gesture based on the tracked series of body motion movements,
filter out invalid body motion movements from the tracked series of body motion movements, the invalid body motion movements
resulting from motions that are not performed by the proper user and/or not performed in accordance with predetermined conditions,

judge whether or not the gesture is authorized, including determining whether the gesture is by a specific user and judging
whether the gesture is performed at the same time that a hardware device is operated by an input from the specific user, and

accept an authorized and valid gesture; and
a client medical software module operable to receive the accepted gesture at a client computer, determine whether or not the
accepted gesture is a recognized gesture for performing a task in accordance with client logic and cause the client computer
to perform the task based on the recognized gesture, wherein the task relates to electroanatomical mapping.

US Pat. No. 9,940,747

MAPPING 3D TO 2D IMAGES

BIOSENSE WEBSTER (ISRAEL)...

1. A method for mapping and displaying a three-dimensional (3D) surface of a heart that contains a volume in a 3D space, the method comprising:providing a mapping arrangement, the mapping arrangement comprising:
a catheter having a distal tip;
a display screen; and
a processor, the processor being operatively connected to the display screen and the catheter;
inserting the catheter into the heart of a patient, moving the tip of the catheter to a plurality of different positions in the heart while tracking and recording said plurality of different positions, and thereby acquiring a set of 3D vertices representing the 3D surface of the heart using the catheter;
defining in the 3D space a first plane that cuts the volume and a second plane, parallel to the first plane, that is external to the volume, thereby partitioning the 3D vertices into a first set of the vertices that are not between the first and second planes and a second set of the vertices that are located between the first and the second planes in the 3D space;
defining a point B on the second plane, and a vertical line through point B which is orthogonal to the second plane;
generating first projected points by: projecting the vertices in the first set along a direction orthogonal to the first plane onto the first plane;
generating second projected points by:
translating the vertices in the second set by respective distances and in respective horizontal directions parallel to the second plane;
wherein the horizontal translation distances of respective vertices in the second set are directly proportional to both (i) their respective distances from the first plane and (ii) to a scaling factor S, the scaling factor S being identical for all vertices in the second set;
wherein the horizontal directions traveled by respective vertices in the second set are directly away from said vertical line through point B; and
further translating the vertices in the second set vertically and orthogonally onto the first plane; and
displaying the first and second projected points together on the display screen as a two-dimensional (2D) representation of the 3D surface of the heart, the displaying of the 2D representation comprising displaying the first projected points overlapping a center area of the 2D representation, and displaying the second projected points positioned radially outward from the center area of the 2D representation and at least partially surrounding the first projected points.

US Pat. No. 9,918,791

DOUBLE LOOP LASSO WITH SINGLE PULLER WIRE FOR BI-DIRECTIONAL ACTUATION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:
an elongated tubular catheter body with at least one lumen extending there through;
a deflectable intermediate section having proximal and distal ends and at least two off-axis lumens extending there through,
the proximal end of the deflectable intermediate section being attached to a distal end of the catheter body;

a distal section distal of the deflectable intermediate section, the distal section comprising:
a tubular structure having a generally straight proximal region attached to the intermediate section, a generally circular
main region generally transverse and distal to the proximal region, and

an elongated support member extending through the distal section, the elongated support member having shape memory, and
at least one electrode carried on the generally circular main region of the distal section;
at least one washer at the distal end of the deflectable intermediate section, the washer having at least two off-axis lumens,
each axially aligned with a respective off axis lumen of the deflectable intermediate section;

a puller wire having two proximal portions and a mid-portion transverse to the two proximal portions, each proximal portion
extending through a respective off-axis lumen of the deflectable intermediate section and a respective off-axis lumen of the
washer, the mid-portion being distal of the washer and extending between the two off-axis lumens of the washer; and

a control handle comprising a deflection mechanism adapted to act on at least one proximal portion of the puller wire anchored
in the control handle to deflect the deflectable intermediate section.

US Pat. No. 9,788,893

CATHETER WITH SOFT DISTAL TIP FOR MAPPING AND ABLATING TUBULAR REGION

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated body having a longitudinal axis;
a distal assembly distal the elongated body, the distal assembly having a helical form comprising a proximal loop and a distal
loop, and a shape-memory support member extending through at least the proximal loop, the proximal loop and the distal loop
being oriented obliquely at an angle relative to the longitudinal axis of the elongated body;

at least one irrigated ablation ring electrode mounted on the proximal loop;
a control handle proximal the elongated body; and
a contraction wire having a proximal end in the control handle and a distal end anchored in the proximal loop, the control
handle including a first control member configured to actuate the contraction wire to contract the proximal loop,

wherein the proximal loop has a first flexibility and the distal loop has a second flexibility, and the second flexibility
is greater than the first flexibility.

US Pat. No. 9,687,289

CONTACT ASSESSMENT BASED ON PHASE MEASUREMENT

Biosense Webster (Israel)...

1. A method of ablation using a body-surface electrode and a probe, comprising the steps of:
inserting the probe into a body of a living subject, the probe having a proximal end and a distal end terminating in a distal
tip, with an ablation electrode affixed to the distal tip, and a reference electrode affixed along the distal end proximal
to the ablation electrode;

passing a current at a known frequency between the reference electrode and the body-surface electrode and reading a reference
waveform having a reference phase from the reference electrode;

while the ablation electrode is in a non-contacting relationship to a target tissue, passing the current at the known frequency
between the ablation electrode and the body-surface electrode and reading a non-contact waveform having a non-contact phase
from the ablation electrode;

making a pre-contact determination by comparing the reference phase to the non-contact phase;
urging the ablation electrode into a contacting relationship with the target tissue;
while the ablation electrode is in the contacting relationship applying a dosage of energy via the ablation electrode to the
target tissue for ablation thereof;

while the ablation electrode is in the contacting relationship with target tissue, iteratively passing the current at the
known frequency between the ablation electrode and the body-surface electrode and intra-operatively reading a contact waveform
having a contact phase from the ablation electrode;

iteratively making intra-operative determinations by comparing the contact phase to the reference phase; and
establishing that one of the intra-operative determinations satisfies a termination criterion for completion of the ablation,
and responsively thereto, terminating the step of applying a dosage of energy.

US Pat. No. 9,955,920

DYNAMIC MAPPING POINT FILTERING USING A PRE-ACQUIRED IMAGE

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:acquiring, from an imaging system, an image of a body cavity;
receiving first and second sets of mapping points from a probe inserted into the body cavity;
performing, by a processor, a first registration between the mapping points in the first set and the image, each of the mapping points in the first set having a respective first point error value, the first registration having a first cumulative error value indicating a quality of the first registration;
generating, using the first registration, a three-dimensional (3D) anatomical map comprising the mapping points in the first set whose respective first point error values are less than a point error threshold;
performing a second registration between the mapping points in the first and the second sets and the image, each of the mapping points in the first and the second sets having a respective second point error value, the second registration having a second cumulative error value lower than the first cumulative error value; and
generating an updated 3D anatomical map comprising the mapping points in the first and the second sets whose respective second point error values are less than the point error threshold.

US Pat. No. 9,956,037

SEALED TWO-WAY MAGNETIC MANIFOLD

Biosense Webster (Israel)...

7. A computer software product, operated in conjunction with a probe that is configured for insertion into a body cavity of a patient, the probe comprising a handle, and an insertion tube having a distal end and an insulating sheath, the insertion tube comprising:an inlet tube configured to receive an irrigation fluid from a pressurized fluid source,
at least first and second outlet tubes configured to deliver the irrigation fluid to respective outlets of the probe,
a manifold containing a chamber coupled between the inlet tube and at least the first and second outlet tubes,
a ball comprising a magnetic material contained inside the chamber,
a plurality of ablation electrodes, the electrodes comprising thin metal layers formed over the insulating sheath of the insertion tube, wherein the respective outlets are connected to respective apertures of the ablation electrodes, and
a magnetic field generator disposed outside the chamber,the product comprising a non-transitory computer-readable medium, in which program instructions are stored, which instructions, when read by a computer, cause the magnetic field generator to generate a variable magnetic field within the chamber so as to move the ball between at least a first position in which the first outlet tube is blocked, a second position in which the second outlet tube is blocked, and a third position, in which neither of the outlet tubes is blocked.

US Pat. No. 9,883,918

METHOD FOR MAPPING VENTRICULAR/ATRIAL PREMATURE BEATS DURING SINUS RHYTHM

Biosense Webster (Israel)...

1. A method of mapping, comprising the steps of:
inserting a probe into a heart of a living subject, the probe having a mapping electrode;
urging the mapping electrode into a contacting relationship with a target tissue in a region of interest of the heart;
providing a memory having programs stored therein;
providing a display; and
providing a processor linked to the display and being coupled to access the memory to execute the programs, the processor
being connectable to receive an input provided by the mapping electrode, wherein the programs cause the processor to perform
the steps of:

obtaining electrocardiographic signals from a target in the heart via the mapping electrode;
holding a series of the electrocardiographic signals in a beat buffer;
freezing the beat buffer to prevent replacement by new beats;
identifying a beat in the beat buffer indicating a PVC (premature ventricular contraction), said beat being a PVC beat,
acquiring a PVC point based on the PVC beat, said PVC point only being acquired if the cycle length of the PVC beat falls
within a predetermined range;

identifying an SR (sinus rhythm) beat from the beat buffer, said SR beat representing normal sinus rhythm;
acquiring an SR point based on said SR beat;
displaying the PVC point and the SR point on a single electroanatomic map;
associating the local activation time (LAT) of the PVC point with the SR point in a single representative display, said association
being accomplished by assigning the LAT of the PVC to the SR point; and

generating a further electroanatomic map, said further electroanatomic map being an SR-PVC map, said SP-PVC map reflecting
the assignment of the LAT of the PVC to the SR point, said SR-PVC map reflecting a geometry of the heart during sinus rhythm,
while reflecting activation time of the heart while experiencing PVC,

whereby ablation may be performed at data-adjusted SR points with an ablation catheter displayed in SR locations, wherein
navigation of an ablation electrode may be guided by the SR-PVC map.

US Pat. No. 9,861,785

CATHETER WITH SERIALLY CONNECTED SENSING STRUCTURES AND METHODS OF CALIBRATION AND DETECTION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter for use with a catheterization system having a plurality of external magnetic field generators, each generating
a position-data magnetic field, comprising:
a flexible tubing; and
a distal section adapted for engagement with patient tissue, the distal section having:
a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;
an internal magnetic field generator positioned in one of the proximal and distal portions, the internal magnetic field generator
generating a pressure-data magnetic field;

three first sensing coils and two second sensing coils positioned in the other of the proximal and distal portions, one of
the first and second sensing coils adapted to sense the pressure-data magnetic field and generate signals representative of
data relating to pressure exerted on the distal section when engaged with tissue, the other of the first and second sensing
coils adapted to sense each of the position-data magnetic fields and generate signals representative of data relating to position
of the distal section;

a first lead serially connecting one of the three first sensing coils and one of the two second sensing coils;
a second lead serially connecting a second one of the three first sensing coils and a second one of the two second sensing
coils; and

a third lead connected to a third one of the three first sensing coils.

US Pat. No. 9,848,833

DETECTION AND DISPLAY OF IRREGULAR PERIODIC WAVE FORMS

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus, comprising:
a display screen;
a processor; and
a catheter comprising an electrocardiogram (ECG) electrode, the ECG electrode being adapted to detect an ECG signal from a
heart of a subject during a cardiac procedure;

wherein the processor is configured to:
receive the ECG signal from the ECG electrode when the catheter is inserted into the heart over multiple heart cycles;
partition the ECG signal into a succession of synchronized segments each having respective start times at a selected annotation
point in the respective heart cycles, wherein said synchronized segments each represent ECG signals from heart cycles occurring
at different time points;

provide a display axis on the display screen, the display axis representing a time period corresponding to one synchronized
segment;

using the display screen, simultaneously display graphical representations of a plurality of synchronized segments on the
display axis, such that synchronized segments corresponding to ECG signals from a plurality of different heart cycles occurring
at different time points are simultaneously overlaid on the display axis, and wherein said graphical representations of the
plurality of synchronized segments at least partially overlap on the display screen;

continuously create additional synchronized segments as the ECG signal is received from the heart of the subject, wherein
graphical representations of newly created synchronized signals are continuously added to the display axis on the display
screen, and wherein graphical representations of older synchronized signals are removed from the display axis after a period
of time;

said processor being further configured to:
determine whether said plurality of graphical representations of the plurality of synchronized segments on the display axis
comprise both (i) one or more synchronized segments which each include an irregular but periodic wave form, and also (ii)
one or more synchronized segments which do not include said irregular but periodic wave form; and

to indicate atrial fibrillation in the subject when condition (i) and (ii) are both satisfied.

US Pat. No. 9,848,943

ABLATION CATHETER WITH DEDICATED FLUID PATHS AND NEEDLE CENTERING INSERT

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body;
a distal tip section having a tip electrode with a distal end, the tip electrode including a needle centering insert;
a needle electrode assembly extending through at least the elongated catheter body and the tip electrode, the needle electrode
assembly being longitudinally movable relative to the catheter body and distal tip section into an extended position and a
retracted position, the needle electrode assembly including a needle electrode;

an injection control handle proximal of the catheter body configured to move the needle electrode assembly into the extended
position and the retracted position;

a fluid path B extending through at least the catheter body and having a distal exit at the distal end of the tip electrode;
and

a fluid path A extending through at least the catheter body and having a distal exit at a distal end of the needle electrode
assembly,

wherein the fluid path B and the fluid path A are isolated from each other,
wherein the tip electrode has a longitudinal passage and the needle centering insert is situated in the longitudinal passage,
and

wherein the fluid path B has a proximal portion that extends through the needle electrode assembly, a distal portion that
extends between the needle electrode assembly and a guide tube surrounding the needle electrode assembly, and a mid-portion
that connects the proximal portion and the distal portion and traverses a side wall of the needle electrode assembly.

US Pat. No. 9,706,937

VENTRICULAR ELECTRICAL ACTIVITY INDICATOR

BIOSENSE WEBSTER (ISRAEL)...

1. A method of guiding a catheter medical procedure, comprising:
providing a catheter, a plurality of body surface electrodes, and a display, wherein the catheter comprises a plurality of
sensing electrodes, the sensing electrodes each being adapted to measure electrical activity;

inserting the catheter into an atrium of a heart of a subject, and positioning said plurality of sensing electrodes at a plurality
of respective positions in the atrium;

detecting electrical activity in the atrium using the sensing electrodes over a time period, said detecting electrical activity
comprising detecting local activation times (LAT) at a plurality of locations in the atrium;

displaying a 4-dimensional LAT map on the display using electrical activity detected by said sensing electrodes in the atrium,
the 4-dimensional LAT map comprising a 3-dimensional electroanatomic map which changes over the time period, the 4-dimensional
LAT map being color-coded based on a color scale with different colors on the 4-dimensional LAT map indicating electrical
activation at different respective times, and same colors on the 4-dimensional LAT map indicating concurrent electrical activation;

attaching the plurality of body surface electrodes to the patient;
detecting ventricular activity in the heart of the patient using the body surface electrodes during said time period, said
ventricular activity comprising ventricular depolarization, the ventricular depolarization being identified by detecting at
least one of a QRS complex and an R wave;

displaying an icon on the display simultaneous to said displaying of the 4-dimensional LAT map, with the icon changing over
the time period, with the icon displayed in an icon color according to said color scale during at least part of the time period,
wherein the icon color when present is displayed in response to ventricular depolarization and corresponds to a ventricular
depolarization time according to said color scale; and

detecting both (i) ventricular depolarization and (ii) first electrical activity in the atrium at a first time point which
is during said time period, and in response to said detecting of (i) ventricular depolarization and (ii) first electrical
activity at the first time point simultaneously displaying both the icon and at least part of the 4-dimensional LAT map in
a first color according to the color scale;

wherein said simultaneous displaying of both the icon and at least part of the 4-dimensional LAT map in the first color indicates
that said first electrical activity detected in the atrium potentially comprises a far-field signal from the ventricle.

US Pat. No. 10,034,653

TISSUE DEPTH ESTIMATION USING GATED ULTRASOUND AND FORCE MEASUREMENTS

BIOSENSE WEBSTER (ISRAEL)...

1. A method for estimating a thickness of heart wall tissue, the method comprising:providing a catheter having a distal tip, the catheter comprising:
an ultrasonic transducer, the ultrasonic transducer adapted to produce ultrasound waves which traverse the heart wall tissue,
and a contact force sensor proximate the distal tip;
providing a mechanical actuator associated with the catheter;
driving the catheter in a reciprocating motion in a direction of the heart wall tissue using the mechanical actuator, wherein the reciprocating motion of the catheter periodically compresses the heart wall tissue in a region of the heart wall tissue in proximity to the distal tip;
receiving a plurality of measurements corresponding to the periodic compression, each measurement indicating (i) a respective mechanical pressure applied to the heart wall tissue, and (ii) one or more round-trip propagation times of an ultrasound wave traversing the heart wall tissue in the presence of the respective mechanical pressure;
selecting a set of the measurements, having mechanical pressures that fall in at least one specified partial sub-range of mechanical-pressure values;
and estimating the thickness of the heart wall tissue based on the round-trip propagation times of the selected set of the measurements,
wherein selecting the set comprises determining one or more time periods in which the mechanical-pressure values fall within the at least one selected partial sub-range, and selecting the measurements that were acquired during the one or more time periods, and
wherein estimating the thickness comprises analyzing repeatability of the round- trip propagation times of the selected measurements among the one or more time periods.

US Pat. No. 9,801,585

ELECTROCARDIOGRAM NOISE REDUCTION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheterization system, comprising:
a catheter having a flexible catheter shaft with a distal portion adapted for insertion into a heart of a subject, the catheter
shaft having a lumen for passing an electrically conductive fluid therethrough to exit the catheter at the distal portion;

a control handle at a proximal end of the catheter, the control handle providing an isolated ground of the system;
an electrical connection having first and second ends, the electrical connection linking the electrically conductive fluid
and the isolated ground provided by the control handle, the first end of the electrical connection being in contact with the
isolated ground provided by the control handle, and the second end of the electrical connection being in contact with the
electrically conductive fluid at a location proximal to the distal portion of the catheter shaft.

US Pat. No. 9,693,822

CATHETER WITH COOLING ON NONABLATING ELEMENT

Biosense Webster (Israel)...

1. A catheter, comprising:
an elongated catheter body;
a tip electrode distal to the catheter body, the tip electrode comprising:
a shell having a proximal neck portion and a distal chamber;
a support member having a proximal portion and a distal portion, the proximal portion of the support member being inserted
in the neck portion of the shell and the distal portion of the support member extending into the distal chamber of the shell,
the proximal portion of the support member having a fluid through-hole extending through an interior of the proximal portion
of the support member; and

a fluid channel provided between the neck portion of the shell and the support member, the fluid channel being on an outer
surface of the distal portion of the support member and in fluid communication with the through-hole in the interior of the
proximal portion of the support member, the fluid channel having at least one axial branch and at least one radial branch,
the fluid channel and through-hole defining a fluid flow path from the interior of the proximal portion of the support member
to the fluid channel on the outer surface of the distal portion of the support member and to the distal chamber.

US Pat. No. 9,693,733

BASKET CATHETER WITH MICROELECTRODE ARRAY DISTAL TIP

Biosense Webster (Israel)...

1. A catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
a basket electrode assembly at the distal end of the catheter body, the basket electrode assembly having proximal and distal
ends and comprising a plurality of spines, the plurality of spines comprising a plurality of electrodes, the distal end of
the basket electrode assembly comprising a substrate body and a plurality of recessed microelectrodes, the substrate body
having an outer surface, and outer surfaces of the plurality of recessed microelectrodes are flush with the outer surface
of the substrate body; and

an irrigation tubing having a distal end at the proximal end of the basket electrode assembly.

US Pat. No. 9,977,096

CONNECTOR WITH ACTIVE SHIELDING

BIOSENSE WEBSTER (ISRAEL)...

1. An electrical connector, comprising:a connector housing;
one or more connector terminals fitted within the connector housing, which are connected to wiring extending from the connector housing and are coupled to interconnect with corresponding connector terminals in a mating connector; and
an active shielding circuit, mounted adjacent to the one or more connector terminals within the connector housing and is configured to sense a first magnetic field in a vicinity of the electrical connector and to generate, based on the sensed magnetic field, a second magnetic field that reduces interference induced in the wiring and the one or more connector terminals by the first magnetic field, the active shielding circuit comprising:
at least one sense coil for sensing the first magnetic field;
at least one generator coil for generating the second magnetic field; and
a drive circuit comprising:
an operational amplifier receiving a first input from a terminal of the at least one sense coil and a second input from a terminal of the at least one generator coil, the operational amplifier capable of amplifying a difference between the first input and the second input;
an integrator receiving an amplified signal from the operational amplifier, the integrator capable of integrating the amplified signal;
a low-pass filter receiving the integrated signal from the integrator, the low-pass filter capable of filtering the integrated signal;
a voltage-to-current (V/I) converter receiving the filtered signal from the low-pass filter, the V/I converter capable of converting a voltage of the filtered signal to a current signal; and
a current source receiving the current signal from V/I converter, the current source driving the at least one generator coil.

US Pat. No. 9,949,658

COMPUTER-AIDED LOCALIZATION OF SITE OF ORIGIN OF CARDIAC ACTIVATION WITH DISCRIMINATOR LEADS

DALHOUSIE UNIVERSITY, Ha...

1. A method for localizing an activation site of origin to an area of the heart comprising:generating a plurality of patient-specific coefficient parameters relating a location of an activation site to integrals of ECG signals during an ablation procedure by
i) for several pacing sites, the number of pacing sites being more than the number of patient-specific coefficient parameters, obtaining a plurality of simultaneously recorded ECG signals from a plurality of leads, from a patient;
ii) calculating an integral of the signal recorded from each of a subset of the plurality of leads;
iii) obtaining the three-dimensional location of the activation site from an electroanatomical system; and
iv) applying a linear regression with intercept to the integrals and to the three-dimensional location of the collected pacing sites to obtain the plurality of patient-specific coefficient parameters;
obtaining a plurality of simultaneously recorded ECG signals of interest from a plurality of leads, corresponding to those used to derive the patient-specific coefficient parameters, from the patient;
calculating an integral of the ECG signal recorded from each of a subset of the plurality of leads for the ECG signals of interest;
applying the patient-specific coefficient parameters to the integrals for the ECG signals of interest to obtain an estimated activation site; and
displaying the estimated activation site as a point on a model of a heart.

US Pat. No. 9,947,091

LOCALLY APPLIED TRANSPARENCY FOR A CT IMAGE

Biosense Webster (Israel)...

1. A method, comprising,receiving three-dimensional tomographic data with respect to a body of a living subject;
using the data to generate a representation of an external surface of the body and displaying the representation on a screen;
inserting an invasive instrument into a region of the body and identifying a position of the instrument in the body;
rendering an area of the external surface surrounding the identified position of the instrument locally transparent in the displayed representation, so as to make visible on the screen an internal structure of the body in a vicinity of the identified position; and
defining a bounding plane with respect to the identified position of the instrument, wherein the area of the external surface is on a first side of the bounding plane, and wherein the internal-structure-made-visible is on a second side, opposite the first side, of the bounding plane.

US Pat. No. 9,848,948

CATHETER ADAPTED FOR USE WITH GUIDE WIRE FOR ACCESSING VESSELS

BIOSENSE WEBSTER (ISRAEL)...

1. An ablation catheter adapted for use with a removable guide wire, the removable guide wire being independent of the catheter,
and the catheter comprising:
an elongated tubular member having a proximal portion, a distal tip end portion, and an intermediate portion with a 3-D shape
between the proximal portion and the distal tip end portion, the elongated tubular member having a plurality of lumens extending
through at least the intermediate portion;

an elongated support member with shape memory extending through a first lumen of at least the intermediate portion of the
tubular member to impart the 3-D shape to the intermediate portion;

at least one ring electrode mounted on the intermediate portion; and
a distal tip end exit port configured to allow the removable guide wire to exit the catheter at the distal tip end of the
distal tip end portion,

wherein:
the proximal portion is configured to extend in longitudinal alignment with the guide wire and comprises a proximal portion
exit port configured to allow the removable guide wire to exit the proximal portion of the tubular member,

the intermediate portion is configured to extend around a portion of the removable guide wire that extends out the proximal
portion exit port to outside the tubular member, and

the distal tip end portion comprises a distal tip end portion entrance port configured to allow the removable guide wire to
enter the distal tip end portion from outside of the tubular member.

US Pat. No. 9,833,157

CARDIAC ACTIVATION TIME DETECTION

Biosense Webster (Israel)...

1. A method for characterizing an electrocardiogram, comprising:
receiving a first unipolar signal from a first location of a heart and a second unipolar signal from a second location of
the heart;

generating a bipolar signal from the first and second unipolar signals;
analyzing the bipolar signal to delineate a time period during which the first and second locations generate a bipolar complex
and rectifying data of the bipolar signal and differentiating the rectified data of the bipolar signal, so as to generate
differentiated data, wherein delineating the time period comprises feeding the differentiated data into a four-state state
machine so as to determine bounds of the time period; and

analyzing the first unipolar signal within the time period to determine an activation time of the first location.

US Pat. No. 9,740,821

REAL-TIME COMMUNICATION BETWEEN MEDICAL DEVICES OVER A DICOM NETWORK

Biosense Webster (Israel)...

1. A method, comprising:
sending over a network from a first medical device to a second medical device a request for data using a non-real-time communication
protocol that comprises messages for conveying medical measurement results; and

in response to the request, producing in the second medical device at least one message that comprises the requested data
and a dummy payload instead of the medical measurement results, and sending over the network the at least one message from
the second medical device to the first medical device using the communication protocol;

wherein at least one network association between the first and second medical devices is opened when the first medical device
sends the request to the second medical device and is closed when the network association is terminated by the first medical
device;

wherein sending the at least one message comprises sending the data in multiple messages in response to the request while
the at least one association is open; and

wherein the medical measurement results comprise an image, and wherein the dummy data comprises a dummy image.

US Pat. No. 10,119,837

MAGNETIC-FIELD GENERATING CIRCUIT FOR A TRACKING SYSTEM

BIOSENSE WEBSTER (ISRAEL)...

1. An apparatus, comprising:a signal generator, configured to supply a signal having both a first dominant frequency and a second dominant frequency; and
an electric circuit, comprising a reactive component, configured to generate, upon the signal being supplied to the electric circuit, a magnetic field having both the first dominant frequency and the second dominant frequency, by virtue of the reactive component simultaneously resonating at both the first dominant frequency and the second dominant frequency,
wherein the reactive component is a first inductor, and wherein the electric circuit further comprises:
a first capacitor, connected in series with the first inductor;
a second inductor, connected in parallel with the first inductor; and
a second capacitor, connected in parallel with the first inductor and in series with the second inductor,
wherein the first capacitor and the first inductor are configured to resonate, collectively, at the first dominant frequency, and
wherein the second capacitor, the first inductor, and the second inductor are configured to resonate, collectively, at the second dominant frequency, and
wherein the first capacitor is configured to have an impedance having a magnitude of less than 20 Ohm at the second dominant frequency, and the second capacitor is configured to have an impedance having a magnitude of greater than 1000 Ohm at the first dominant frequency.

US Pat. No. 10,039,898

CATHETER SHEATH INTRODUCER WITH DIRECTIONAL RETENTION DAMPER

Biosense Webster (Israel)...

1. A catheter sheath introducer adapted for use with a medical device, comprising:a hub;
an elongated sheath comprising a tubular structure with a distal end and a proximal end, the tubular structure having at least one layer with an inner circumferential surface defining a lumen, the hub connected to the proximal end of the sheath, the elongated sheath being flexible such that the elongated sheath is insertable into and bendable within a patient's vasculature; and
a plurality of damper sets, each of the plurality of damper sets being located distal of a distal end of the hub and comprising four circumferentially aligned dampers aligned along a same circumference of the inner circumferential surface and arranged in two diametrically opposing pairs, the circumferentially aligned dampers extending inwardly from the inner circumferential surface, each of the circumferentially aligned dampers comprising a base in contact with the inner circumferential surface of the elongated sheath and a free distal end, the bases of the circumferentially aligned dampers of each of the plurality of damper sets being spaced from each other along the same circumference of the inner circumferential surface and the free distal ends of at least two of the circumferentially aligned dampers of each of the plurality of damper sets being in contact with each other when the circumferentially aligned dampers are in a neutral position,
wherein the distal end of one of the circumferentially aligned dampers of one of the diametrically opposing pairs is in contact with the distal end of another of the circumferentially aligned dampers of the same diametrically opposing pair when the circumferentially aligned dampers are in the neutral position, the circumferentially aligned dampers each having a unidirectional configuration and being biased toward the neutral position;
wherein the plurality of damper sets is configured to contact and apply a retention force on the medical device received in the lumen of the elongated sheath, the retention force being applied to hold the medical device in a selected position relative to the sheath and to resist unintentional rotational and longitudinal movement from the selected position, the circumferentially aligned dampers being configured to deform upon contacting the medical device, and the circumferentially aligned dampers defining an open passage when the circumferentially aligned dampers are in the neutral position.

US Pat. No. 9,980,772

MONITORING TISSUE TEMPERATURE WHILE USING AN IRRIGATED CATHETER

Biosense Webster (Israel)...

1. A method of performing an ablation procedure on tissue in a body, the ablation procedure having a non-ablation stage where no ablation is being performed and an ablation stage where the tissue is being ablated, comprising:inserting a probe having at least one electrode and at least one sensor into the body in proximity to the body tissue;
creating a mathematical model of physical parameters representative of a probe in proximity to body tissue during the ablation procedure performed by the probe by generating calculated non-ablative values of a subgroup for the non-ablation stage and generating calculated ablative values of the subgroup for the ablation stage;
measuring a subgroup of the physical parameters during the non-ablation stage of the ablation procedure so as to generate measured non-ablative values of the subgroup;
ablating the body tissue with the probe during a first ablation stage;
measuring the subgroup of the physical parameters during the ablation stage of the ablation procedure so as to generate measured ablative values of the subgroup; and
comparing the measured non-ablative values with the calculated non-ablative values, and comparing the measured ablative values with the calculated ablative values, so as generate optimal values of the physical parameters to evaluate the ablation of the tissue.

US Pat. No. 9,974,460

BASKET-SHAPED CATHETER WITH IMPROVED DISTAL HUB

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter comprising:an elongated catheter body extending along a longitudinal axis, the elongated catheter body having a proximal end and a distal end;
a flexible wire assembly positioned at the distal end of the elongated catheter body formed from a single piece of shape memory material, the flexible wire assembly having a plurality of flexible wires, each flexible wire having a proximal end and a distal end, the flexible wire assembly further having a distal hub extending from the distal ends of at least a portion of the plurality of flexible wires, the distal hub configured to be generally parallel to the longitudinal axis of the elongated catheter body when the catheter is in a first operational state and generally perpendicular to the longitudinal axis of the elongated catheter body when the catheter is in a second operational state;
a plurality of spines formed from the plurality of flexible wires; and
a plurality of electrodes and cabling attached to each spine, the plurality of electrodes and cabling having a corresponding plurality of wires coiled on a core and covered by a sheath such that each electrode is attached through the sheath to one of the plurality of wires, such that spines bow radially outwardly in the second operational state and are arranged generally along the longitudinal axis of the catheter body in the first operational state.

US Pat. No. 9,907,480

CATHETER SPINE ASSEMBLY WITH CLOSELY-SPACED BIPOLE MICROELECTRODES

Biosense Webster (Israel)...

1. An electrophysiological catheter comprising:
an elongated body;
a distal electrode assembly comprising:
a plurality of spines, each of the spines having a free distal end and a proximal end extending from a distal end of the elongated
body; and

a flexible panel on at least one of the spines, the flexible panel having a substrate conforming to a surface of its respective
spine, at least one pair of microelectrodes, a trace for each of the microelectrodes, and a soldering pad for each of the
microelectrodes, wherein each trace electrically couples a respective one of the microelectrodes and a respective one of the
soldering pads.

US Pat. No. 9,875,578

VOXELIZATION OF A MESH

Biosense Webster (Israel)...

1. A method for three-dimensional (3D) rendering, comprising:
receiving a group of 3D triangles defining a triangular mesh of a surface, each 3D triangle in the group having three 3D vertices
with respective 3D coordinates;

transforming each 3D triangle into a corresponding two-dimensional (2D) triangle having three 2D vertices corresponding respectively
to the 3D vertices, each 2D vertex having respective 2D pixel coordinates and a triplet of pixel attributes corresponding
to the 3D coordinates of a corresponding 3D vertex;

passing each 2D triangle to a graphics processor, which treats the triplet of pixel attributes of each 2D vertex as interpolatable
values;

in the graphics processor, computing respective triplets of interpolated pixel attributes for pixels within each 2D triangle
by interpolation between the pixel attributes of the 2D vertices of the 2D triangle; and

rendering a 3D image of the surface by converting the interpolated pixel attributes computed by the graphics processor into
voxel coordinates in the 3D image.

US Pat. No. 10,085,808

ADJUSTABLE TRACKING SENSOR SUITABLE FOR DIFFERENT RIGID TOOLS

Biosense Webster (Israel)...

1. An apparatus, comprising:a rigid gripper configured to fasten around a cylindrical object;
a pair of conductors attached to the gripper so as to make contact with one another, while the gripper is fastened around the cylindrical object, at a location along a length of the conductors that varies responsively to a diameter of the cylindrical object; and
a sensing circuit configured to measure an impedance of a current passing through the pair of conductors and to generate an indication of the diameter responsively to the impedance,
wherein the rigid gripper comprises a pair of jaws rotating about a common hinge so as to fasten around the cylindrical object, and wherein each of the conductors is attached to a respective jaw.

US Pat. No. 9,993,611

MULTISHAPE CATHETER

BIOSENSE WEBSTER (ISRAEL)...

1. A method for forming a probe, comprising:configuring a flexible insertion tube for insertion into a body of a subject via a body lumen;
introducing a sequence of tubular modules into the insertion tube, each module comprising a rigid tube segment having a respective preset shape and containing internal grooves on an interior surface of the tube segment;
threading a flexible expander tube through the sequence of the tubular modules, the flexible expander tube having external grooves configured to engage the internal grooves within the tube segment of each of the tubular modules when the expander tube is expanded, so as to hold the tubular modules in mutual alignment, wherein the tubular modules are able to move out of the mutual alignment when the expander tube is unexpanded; and
inserting an expansion element into the flexible expander tube so as to expand the expander tube.

US Pat. No. 9,974,927

CATHETER WITH FLAT BEAM DEFLECTION IN TIP

BIOSENSE WEBSTER (ISRAEL)...

1. A method of manufacturing a catheter, the catheter comprising:an elongated catheter body comprising a first tubular structure having first central lumen, a distal end and a proximal end;
a deflectable section having a second tubular structure having a second central lumen, and a proximal end that is distal of the proximal end of the catheter body;
a flat beam having first and second opposing surfaces, the flat beam extending through at least the second central lumen of the deflectable section, the flat beam defining a first sub-lumen and a second sub-lumen;
a puller wire configured with first and second segments and a U-bend segment therebetween, the U-bend segment anchored to the distal end of the flat beam, the first segment extending through the first sub-lumen and through the first central lumen of the catheter body, the second segment extending through the second sub-lumen and through the first central lumen of the catheter body;
a first compression coil surrounding a portion of the first segment extending through the catheter body, a second compression coil surrounding a portion of the second segment extending through the catheter body;
a pair of first and second half-cylindrical brackets, the first half-cylindrical bracket being mounted on a first surface of the beam, the second half-cylindrical bracket being mounted on a second surface of the beam, the first and second half-cylindrical brackets forming a hollow body generally surrounding the beam at or near a junction between the catheter body and the deflectable section, wherein the distal end of the first tubular structure covers a proximal portion of the hollow body and a proximal end of the second tubular structure covers a distal portion of the hollow body, wherein each bracket has at least two holes, and each of the first and second tubular structures has an inner layer with at least one interlocking node extending into a respective hole in each bracket,
the method comprising:
wrapping the junction between the first and second tubular structures in one or more heat shrink tubings to form a tube assembly;
heating the one or more heat shrink tubings to recover around the junction between the first and second tubular structures; and
heating the tube assembly to reflow inner layers of the first and second tubular structures to form the interlocking nodes within the brackets.

US Pat. No. 9,962,217

ESTIMATION AND MAPPING OF ABLATION VOLUME

Biosense Webster (Israel)...

1. A method of ablation, comprising the steps of: inserting a probe into a body of a living subject; urging the probe into contact with a tissue in the body; determining a mechanical force that is exerted by the probe against the tissue; calculating a rate of ablation as a function of a power level and the mechanical force; applying a specified dosage of energy for an application time and at the power level to the tissue for ablation thereof, wherein at least one of the application time of the dosage and the power level depend on the mechanical force; and controlling the rate of ablation by varying at least one of the power level and the mechanical force.

US Pat. No. 9,907,610

SPRING-LOADED BALLOON

Biosense Webster (Israel)...

1. An ablation apparatus comprising:
a probe having a hollow shaft, a longitudinal axis and a distally disposed balloon assembly, the balloon assembly comprising:
a spring having a resting axially elongated configuration and a torsed, axially shortened configuration;
an inflatable balloon mechanically linked to the spring and enclosing the spring, the balloon having a wall; and
a flexible sheath disposed about the spring within the balloon, the sheath and the wall of the balloon defining a chamber
to contain a fluid flowing therein and thereout for inflation and deflation of the balloon, wherein inflation urges the spring
into the torsed, axially shortened configuration and deflation permits the spring to return to the resting axially elongated
configuration.

US Pat. No. 9,757,182

IDENTIFICATION AND VISUALIZATION OF GAPS BETWEEN CARDIAC ABLATION SITES

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising:
receiving locations of multiple ablation sites formed on a surface of a heart;
measuring distances among at least some of the ablation sites based on the locations;
based on the distances, determining a second ablation site that is a closest neighbor to a first ablation site;
identifying a gap between the first and second ablation sites and;
determining whether the gap that meets an alerting criterion; and
indicating the identified gap to an operator;
wherein when the gap is determined to meet the alerting criterion, the step of indicating comprises highlighting to the operator
that the identified gap is a gap that has been determined to meet the alerting criterion.

US Pat. No. 9,757,195

IRRIGATED CATHETER WITH FLUID EVACUATION

Biosense Webster (Israel)...

1. An ablation catheter for use with a suction source:
an elongated catheter body;
a distal section distal the catheter body, the distal section comprising:
a tip electrode adapted for ablation and irrigation;
a tubular member extending between the catheter body and the tip electrode, the tubular member having at least first and second
lumens;

at least two ring electrodes proximal of the tip electrode, the at least two ring electrodes comprising at least a distal-most
ring electrode and an adjacent ring electrode;

at least one dedicated evacuation port in a sidewall of the tubular member between the distal-most ring electrode and the
adjacent ring electrode, the at least one dedicated evacuation port being in suction communication with the first lumen;

at least one dedicated irrigation port in the tip electrode in fluid communication with the second lumen;
a fluid evacuation path extending at least through the catheter body and the first lumen, the fluid evacuation path configured
to provide suction communication between the suction source and the at least one dedicated evacuation port.

US Pat. No. 9,649,046

LINE OF BLOCK DETECTION

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising the steps of:
inserting a probe into a heart of a living subject, the probe having a plurality of electrodes;
recording electrograms from the electrodes at respective locations in the heart;
determining slopes and annotations in the electrograms within time windows;
establishing relationships among the slopes and annotations from different ones of the electrograms; and
determining from the relationships lines of conduction block in the heart;
wherein determining slopes and annotations comprises the steps of:
determining bipolar windows in the electrograms;
annotating local activation times within the bipolar windows;
determining from readings of a set of electrodes that a block point exists in a region of the set of electrodes;
repositioning the local activation times responsively to the block point; and
determining revised windows that include respective local activation times; and
wherein establishing relationships among the slopes and annotations comprises:
identifying primary slopes and secondary slopes in the electrograms;
determining whether the electrodes are in contact with the heart; and
determining whether the primary slopes and the secondary slopes are coupled to one another.

US Pat. No. 9,615,764

REAL-TIME COLORING OF ELECTROPHYSIOLOGICAL MAP

BIOSENSE WEBSTER (ISRAEL)...

1. A method of catheterization, comprising the steps of:
inserting a probe into a heart of a living subject, the probe having a plurality of electrodes and sensors;
displaying an electroanatomical map of the heart on a monitor; and
during a time interval that does not exceed a duration of a cardiac cycle of the heart, performing the further steps of:
reading data from at least one of the electrodes and sensors;
invoking a processor to perform an algorithm on the data, the algorithm having a plurality of inputs and a result, wherein
the data comprises one of the plurality of inputs and the result comprises a transformation of the data; and

rendering the result on the monitor to modify the electroanatomical map; and
wherein the algorithm comprises the steps of:
selecting first electrodes from the electrodes wherein the first electrodes are in contact with tissue of the heart;
identifying relative motion of the first electrodes with the tissue;
selecting second electrodes from the first electrodes, wherein the second electrodes exhibit a predetermined amount of the
relative motion;

selecting third electrodes from the second electrodes, wherein respective locations of the third electrodes in successive
beats have a correlation score below a predetermined threshold; and

generating the result from data obtained from the third electrodes.

US Pat. No. 10,136,836

IMMUNITY FROM MAGNETIC DISTURBANCE FOR A MAGNETIC LOCATION TRACKER

BIOSENSE WEBSTER (ISRAEL)...

1. A magnetic tracking system for positioning of instruments during a medical procedure on the head of a patient comprisinga ferromagnetic sheet;
a frame having an opening for surrounding a patient's head;
said frame mounted in proximity to the ferromagnetic sheet and having at least one radiator mounted therein
said at least one radiator having at least one coil for producing an alternating magnetic field which induces a respective magnetic image of the coil in the ferromagnetic sheet and wherein the magnetic image acts as a magnetic field radiator; and
a solid sheet of thermal insulation, mounted between the ferromagnetic sheet and the at least one radiator so as to prevent transfer of thermal energy from the at least one radiator to the ferromagnetic sheet.

US Pat. No. 10,080,608

CATHETER FOR TREATMENT OF ATRIAL FLUTTER HAVING SINGLE ACTION DUAL DEFLECTION MECHANISM

Biosense Webster (Israel)...

1. A method of accessing tissue in a patient, the method comprising:inserting into the patient a distal end of a deflectable catheter comprising:
an elongated catheter body having an outer wall, proximal and distal ends, and at least one lumen extending therethrough,
a distal tip section comprising a flexible tubing having a proximal end and a distal end and a plurality of lumens extending therethrough, the proximal end of the tip section being fixedly attached to the distal end of the catheter body, the distal tip section further comprising a nitinol tube having slots formed therein,
a puller wire extending through the elongated catheter body and distal tip section, and
a control handle at the proximal end of the elongated catheter body; and
contacting the distal tip section with the tissue by manipulating the control handle to thereby deflect the elongated catheter body and the distal tip section, the deflection comprising a first pulling of the puller wire with a first force sufficient to cause a distal deflection in the distal tip section and a second pulling of the puller wire with a second force sufficient to cause a proximal deflection in the elongated catheter body.

US Pat. No. 10,016,233

TREATMENT OF ATRIAL FIBRILLATION USING HIGH-FREQUENCY PACING AND ABLATION OF RENAL NERVES

BIOSENSE WEBSTER (ISRAEL)...

1. A method for the treatment of a patient having a blood pressure comprising the steps of:inserting an ablation catheter having an electrode mounted thereon into a renal artery of a patient wherein the renal artery has a wall defining a lumen;
stimulating a portion of the wall of the lumen of the renal artery using high-frequency pulses;
monitoring the blood pressure of the patient at least before and during, or at least before and after, stimulating a portion of the wall;
identifying a location on the wall of the lumen of the renal artery where the stimulation causes a decrease in the blood pressure of the patient thereby indicating the presence of a renal nerve near the location; and,
ablating the renal nerve near the identified location.

US Pat. No. 9,955,889

REGISTRATION MAPS USING INTRA-CARDIAC SIGNALS

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising of steps of:using a first system to generate a first electroanatomic map of a heart of a living subject;
using a second system that is different to the first system to generate a second electroanatomic map of the heart;
identifying areas with common electrical events in the first and second electroanatomic maps and finding in those areas at least three points in each of the first and second electroanatomic maps where the local activation times of points in the first and second electroanatomic maps do not differ by more than a first threshold value and where the respective distances between the points on each electroanatomic map do not exceed a second threshold value;
using the at least three points to designate common spatial locations that correspond to first electrical events on the first electroanatomic map and second electrical events on the second electroanatomic map;
aligning the common spatial locations of the first electroanatomic map and the second electroanatomic map to establish a set of aligned maps; and
using the set of aligned maps to guide a probe to a point of interest.

US Pat. No. 9,949,657

DISPLAYING MULTIPLE-ACTIVATION AREAS ON AN ELECTROANATOMICAL MAP

Biosense Webster (Israel)...

1. A method, comprising:contacting a distal end of a catheter along a surface of a heart, the distal end of the catheter having one or more electrodes configured to sense intracardiac ECG signals,
receiving the ECG signals in a processor operatively connected to the electrodes by an interface;
analyzing the ECG signals in the processor to identify at least one multiple-activation area of the surface of the heart, wherein the at least one multiple-activation area of the surface of the heart occurs where at least two different local activations of the same area are received during a single cardiac cycle of the heart;
generating an electroanatomical map of the surface of the heart in the processor and displaying the electroanatomical map of the surface of the heart on a display device; and
displaying, on the electroanatomical map of the surface of the heart, the multiple-activation area in a manner that indicates a time difference between respective times of the two local activations.

US Pat. No. 9,784,922

ELECTRO-OPTICAL CONNECTOR WITH HOT ELECTRICAL CONTACT PROTECTION

BIOSENSE WEBSTER (ISRAEL)...

1. A cable connector, comprising:
a housing comprising a base, a lip that surrounds the base and defines an aperture configured to receive a mating plug, and
a plurality of structures arranged in the aperture that protrude from the base;

a plurality of electrical contacts enclosed by the housing and configured to convey electrical signals, the electrical contacts
having respective first proximal and first distal ends, the first proximal ends being implanted in the base so that the first
distal ends are recessed within the aperture at a first distance from the base; and

one or more optical fiber terminals containing end portion of an optical fiber configured to convey optical signals;
wherein the plurality of structures protrude to a second distance from the base, which is greater than the first distance,
the plurality of structures comprising:

a central structure disposed centrally within the plurality of electrical contacts;
a plurality of structures regularly spaced around the central structure and arranged to partially surround the plurality of
electrical contacts;

at least one of the plurality of structures regularly spaced around the central structure containing the one or more optical
fiber terminal;

wherein the arrangement of the plurality of structures is such that when a finger enters the aperture it will press against
at least one of the plurality of structures and thereby be prevented from touching the plurality of electrical contacts.

US Pat. No. 10,136,945

ABLATION CATHETER WITH LIGHT-BASED CONTACT SENSORS

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter, comprising:an elongated body;
an expandable element at a distal end of the elongated body;
at least one electrode disposed on the expandable body;
at least one contact sensor disposed on the expandable element and adjacent to the at least one electrode;
at least one light emitting element electrically connected to the contact sensor; and
a light sensor, the light sensor configured to receive a light signal from the at least one light emitting element.

US Pat. No. 10,130,420

CATHETER WITH MEMBRANED SPINES FOR PULMONARY VEIN ISOLATION

Biosense Webster (Israel)...

1. A method of using a catheter that includesan elongated catheter shaft having at least one lumen therethrough, the catheter shaft defining a longitudinal axis; and
a distal electrode assembly having:
a plurality of spines situated around the longitudinal axis, each spine having a free distal end and a proximal end anchored in the catheter shaft, each spine having at least one ring electrode; and
a membrane member spanning over at least a portion of each spine, the membrane member having a first surface with at least one surface electrode,
wherein the membrane member defines a distal concavity when the distal electrode assembly is out of tissue contact and the membrane member defines a distal convexity when the distal electrode assembly is in tissue contact; the method comprising the steps of:
positioning the distal electrode assembly on an ostium with the distal concavity facing the ostium, the distal ends of the spines in contact with tissue generally surrounding the ostium, and the membrane member spanning across the ostium; and
advancing the distal electrode assembly into the ostium by pushing distally on the catheter shaft to flex the spines and invert the membrane member within the ostium, thereby placing the at least one surface electrode in contact with the ostium.

US Pat. No. 9,931,052

CATHETER WITH COMBINED POSITION AND PRESSURE SENSING STRUCTURES

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter for use with a catheterization system having a plurality of magnetic field generators, each generating a position-data magnetic field, comprising:a flexible tubing; and
a distal section adapted for engagement with patient tissue, the distal section having:
a proximal portion, a distal portion and a flexible joint between the proximal portion and the distal portion;
a distal section magnetic field generator positioned in one of the proximal and distal portions, the distal section magnetic field generator adapted to generate a pressure-data magnetic field;
at least two sensing coils positioned in the other of the proximal and distal portions;
wherein at least one of the at least two sensing coils is configured to sense each position-data magnetic field and the pressure-data magnetic field and generate signals representative of data relating to position of the distal section and data relating to pressure exerted on the distal section when engaged with the patient tissue; and
wherein the at least one of the at least two sensing coils has a respective lead connected thereto configured to transmit signals for signal processing.

US Pat. No. 9,895,073

DUAL BASKET CATHETER

Biosense Webster (Israel)...

1. A catheter comprising an elongated catheter body having proximal and distal ends and at least one lumen therethrough and
a basket-shaped electrode assembly at the distal end of the catheter body, the basket-shaped electrode assembly comprising
a plurality of spines made from a shape memory material, each spine having a preformed basket-shaped expanded configuration
and being connected at their proximal and distal ends, each spine comprising at least one electrode and configured to deflect
outwards into the preformed expanded configuration, wherein the basket-shaped electrode assembly has a proximal basket area
and a distal basket area each formed by the same plurality of spines, and each having different equatorial diameters when
the basket-shaped electrode assembly is in the expanded configuration.

US Pat. No. 10,052,147

TOUCH FREE OPERATION OF ABLATOR WORKSTATION BY USE OF DEPTH SENSORS

BIOSENSE WEBSTER (ISRAEL)...

1. A system for touch-free operation of an ablator workstation by an associated user, comprising: a depth sensor configured to detect an initial location and a subsequent location of a body part of the associated user; and a processor with a memory device, wherein the memory device is configured to store instructions that, when executed by the processor, cause the processor to: receive the detected initial location and the detected subsequent location of the body part, deduce a gesture based on the detected initial location and the detected subsequent location, validate the gesture based on a physical characteristic of the gesture, predict a location of a subsequent user movement location based on an initial user movement location, authorize the gesture as being from the associated user when the subsequent user movement location is within the predicted location, when the subsequent user movement location is outside the predicted location, authorize the gesture as being from the associated user based on facial recognition detected by the depth sensor, and cause the ablator workstation to perform an ablator task after the gesture is validated and authorized.

US Pat. No. 9,913,685

IRRIGATED ABLATION CATHETER HAVING IRRIGATION PORTS WITH REDUCED HYDRAULIC RESISTANCE

Biosense Webster (Israel)...

1. An irrigated ablation catheter, comprising:
an elongated catheter body;
a deflectable section distal to the catheter body;
a tip electrode distal to the deflectable section, the tip electrode comprising:
an outer shell defining a cavity, the shell having a predetermined plurality of fluid ports, each contributing to a total
fluid output area of the tip electrode;

an internal member including an off-axis noncircular fluid inlet into the tip electrode, the fluid inlet having a fluid input
area;

wherein each fluid port is tapered, and the tip electrode has a diffusion ratio of less than 2.0.

US Pat. No. 10,143,394

BASKET CATHETER WITH DEFLECTABLE SPINE

Biosense Webster (Israel)...

1. A method of mapping or ablating tissue in a cavernous region, the method comprising:introducing a catheter comprising:
an elongated catheter body having proximal and distal ends and at least one lumen therethrough;
an electrode assembly at the distal end of the catheter body, the electrode assembly having proximal and distal ends and comprising a plurality of spines, the spines comprising a plurality of electrodes;
an expander having proximal and distal ends, the expander forming a longitudinal axis of the electrode assembly, the spines being attached at their proximal ends to the catheter body and at their distal ends to the expander;
at least one puller wire that extends through the expander, the at least one puller wire having a distal end anchored in the expander at a location distal of the distal end of the catheter body and proximal of the distal end of the electrode assembly; and
a control handle proximal of the catheter body, the control handle having an actuator adapted to move the at least one puller wire,
wherein the electrode assembly has an expanded arrangement when the expander is moved proximally along the longitudinal axis of the electrode assembly relative to the catheter body and the electrode assembly has a collapsed arrangement when the expander is moved distally along the longitudinal axis relative to the catheter body, and
wherein the expander is adapted to deflect in at least one direction when the at least one puller wire is moved by the actuator;
contacting the tissue in the cavernous region with the electrode assembly; and
mapping or ablating the tissue in the cavernous region with the plurality of electrodes.

US Pat. No. 10,145,760

STATUS OF AN IRRIGATION PUMP

Biosense Webster (Israel)...

1. A pump mechanism, comprising:two compartments formed by first and second walls with a paddle located between the first and second walls configured to receive in each of the two compartments,
first and second flexible containers, each flexible container holding a fluid an having an outlet, the paddle having first and second paddle sides;
a motor coupled to the paddle to drive the paddle towards one of the first and second walls together so as to force the fluid out of the container through the outlet;
first and second electrodes fixed respectively to the first and second walls;
third and fourth electrodes fixed respectively to the first and second paddle sides; and
a processor coupled to the first, second, third and fourth electrodes to measure a capacitance between a pair of the first and third electrodes or second and fourth electrodes and to estimate, responsively to the capacitance, a volume of the fluid remaining in the respective flexible containers.

US Pat. No. 10,128,594

CONNECTORS HAVING THREE-DIMENSIONAL SURFACES

Biosense Webster (Israel)...

1. Apparatus, comprising:a connector body comprising at least one mating surface having a first longitudinal end, and a second longitudinal end that is narrower than the first longitudinal end;
a plurality of electrically-conductive terminals coupled to the mating surface of the connector body;
wherein the mating surface is an inner surface of the connector body, such that the connector body is a female-connector body; and
wherein the female-connector body is shaped to define at least one protrusion that protrudes from the second longitudinal end of the female-connector body toward the first longitudinal end of the female-connector body, the protrusion not being at a transverse center of the female-connector body.

US Pat. No. 10,105,516

CATHETER WITH IMPROVED TORQUE TRANSMISSION

BIOSENSE WEBSTER (ISRAEL)...

1. A catheter, comprising:an elongated catheter body comprising a first tubular structure having first central lumen, a distal end and a proximal end, the first tubular structure having a layer of thermoplastic material;
a deflectable section having a second tubular structure having a second central lumen, and a proximal end that is distal of the proximal end of the catheter body, the second tubular structure having a layer of thermoplastic material;
a joint between the distal end of the first tubular structure and the proximal end of the second tubular structure, the joint including a first half cylindrical bracket with two first edges and a second half cylindrical bracket with two second edges, each bracket having at least one receiving formation;
a beam having a generally rectangular cross-section with first and second opposing surfaces, at least a portion of the beam extending through the joint; and
wherein the two first edges are affixed to the first surface of the beam and the two second edges are affixed to the second surface of the beam such that the first and second brackets form a hollow body surrounding the portion of the beam, a distal portion of the hollow body being covered by the layer of thermoplastic material of the second tubular structure, a proximal portion of the hollow body being covered by the layer of thermoplastic material of the first tubular structure, the layers of thermoplastic materials of the first and second tubular structures each having at least one node extending into the receiving formation.

US Pat. No. 10,105,117

COMPENSATION FOR HEART MOVEMENT USING CORONARY SINUS CATHETER IMAGES

BIOSENSE WEBSTER (ISRAEL)...

1. A method, comprising the steps of:introducing a catheter into a coronary sinus of a heart of a living subject;
while the catheter is in the coronary sinus acquiring a first set of frames at first and second primary angles, the first set of frames comprising 2-dimensional images of the catheter using an imaging device;
thereafter acquiring a second set of frames at first and second primary angles, the second set of frames comprising 2-dimensional images of the catheter using the imaging device;
establishing respective 2-dimensional models of the catheter in frames of the first set and the second set, the 2-dimensional models comprising respective tracked 2-dimensional paths of the catheter;
synchronizing the first set with the second set by identifying a first pair of frames from the first set and the second set taken at the first primary angle and a second pair of frames from the first set and the second set taken at the second primary angle that are in respective phases of a cardiorespiratory cycle;
constructing first and second 3-dimensional models of the catheter from the synchronized frames using the respective 2-dimensional models;
geometrically transforming the first and second 3-dimensional models to minimize a distance function there between; and
displaying the transformed 3-dimensional models;
wherein the subject has a sagittal plane and wherein the steps of acquiring the first set and acquiring the second set each comprise acquiring frames at a first primary angle and at a second primary angle with the sagittal plane; and
wherein the difference between first and second primary angles varies by up to 120°.

US Pat. No. 10,045,707

BASKET CATHETER WITH FAR-FIELD ELECTRODE

Biosense Webster (Israel)...

1. An apparatus comprising:a catheter having an elongated catheter body, the catheter body having an interior, proximal end, a distal end and at least one lumen therethrough;
a basket-shaped assembly at the distal end of the catheter body, the basket-shaped assembly having a longitudinal axis, a proximal extremity and a distal extremity and comprising a plurality of splines connected at the proximal extremity and the distal extremity, the splines comprising a plurality of spline electrodes, the basket-shaped assembly configurable in an expanded arrangement wherein the splines bow radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis of the catheter body;
a contraction wire attached to the distal extremity of the basket assembly and slideably engaged within the elongated body, the contraction wire being configured to retract and or expand the basket-shaped assembly; and
a far-field electrode disposed on the contraction wire and located in the interior of the expanded basket-shaped assembly, the far-field electrode being configured to detect far-field electrical activity that interferes with cardiac signal acquisition.

US Pat. No. 10,044,447

LINEAR ISOLATION AMPLIFIER WITH OUTPUT DC VOLTAGE CANCELLATION

BIOSENSE WEBSTER (ISRAEL)...

1. An electronic circuit, comprising:an isolation amplifier, having a first input terminal coupled to receive an input AC-signal and a linear opto-isolator, which has a first output terminal and is coupled to provide at the first output terminal a unipolar signal, having an AC-component proportional to the input AC signal; and
a transimpedance receiver, comprising:
a first operational amplifier, having a second output terminal and a first differential input terminal and a second differential input terminal, with the first differential input terminal coupled to receive and amplify the unipolar signal output from the first output terminal so as to provide an output signal from the first operational amplifier circuit at the second output terminal; and
a second operational amplifier, which is configured as an integrator, and which has a third output terminal coupled to the second differential input terminal and has a third differential input terminal and a fourth differential input terminal, with the third differential input terminal coupled to receive the output signal from the second output terminal and the fourth differential input terminal connected to a ground.

US Pat. No. 9,905,956

PREVENTING UNWANTED CONTACT BETWEEN TERMINALS

BIOSENSE WEBSTER (ISRAEL)...

1. A method for establishing an electrical connection between a male connector and a female connector, comprising:
providing a male connector comprising a male connector body having a male mating surface comprising a plurality of electrically-conductive
male-connector terminals and defining a hollow male connector core;

providing a longitudinal insert configured for inserting into the hollow male connector core;
providing a female connector configured to matingly receive the male-connector body and having a female mating surface comprising
a plurality of electrically-conductive female-connector terminals defining a recess;

inserting the longitudinal insert at least partially into the male connector core;
second inserting the male connector body into the female connector, wherein each male-connector terminal is not in contact
with a respective female-connector terminal; and

bringing each male-connector terminal into contact with a respective female-connector terminal.

US Pat. No. 9,895,079

ELECTROPOTENTIAL MAPPING

Biosense Webster (Israel)...

1. A method for forming an electropotential map, comprising:
measuring locations of points on a surface of a body organ;
measuring electrical potentials of a subset of the points;
assigning respective resistances to line segments joining the points so as to define a resistor mesh; and
generating an electropotential map of the surface by applying an harmonic function to the resistor mesh responsive to the
measured electrical potentials.